MitoRx Therapeutics is a biotechnology company focused on developing innovative therapeutics aimed at reversing mitochondrial dysfunction. The company targets a range of conditions, including neuromuscular disorders, metabolic diseases, and dementia. By specializing in mitochondrial-protective therapies, MitoRx seeks to address the progression of challenging diseases, particularly rare indications, while also engaging in partnerships for broader applications. Their work enables healthcare professionals to potentially halt the decline associated with dystrophy and neurodegeneration.
At XENO we believe biology speaks biology best. Many foundational problems in diagnostics and bioengineering are solvable if biology could just do more of the work. But current biotech isn’t smart enough. We are interested in changing the status quo by systematizing biologic units and constructing modular composition rules. We are a team of engineers and biologists with specialized expertise and common system goals.
AI is transforming healthcare but it’s potential to revolutionize brain health care is what will be transformative. BrainKey is an AI + neuroscience company started by two Stanford PhDs that is developing a platform to help older adults manage their brain health so that they can identify problems early, track how their brain is changing over time and get access to the right and best care for their needs quickly and easily. On the surface, BrainKey is a simple “patient-facing” web-interface designed specifically for patients to understand their brain health. Internally, the platform is powered by “Rollerblade” an advanced cloud infrastructure and AI, designed in-house to process and deploy brain MRI and biomedical data at scale so that both patients and their physicians have the information they need. Brain health problems such as Alzheimer’s disease are devastating for the patient and their families. 1 in 3 people will suffer a brain health issue at some point during their lifetime and the chances only increase with age. BrainKey envisions a future where brain health is tracked across a patient’s lifetime so that problems are identified early and treated before symptoms are ever able to take hold and wreak havoc.
Collaborate Healthcare is a technology startup focused on enhancing clinical outcomes for pediatricians and general practitioners through innovative IT solutions. The company has developed a healthcare platform that includes patient relationship management (CRM) and collaboration tools, designed to transform medical care delivery into a technology-driven, patient-centered, team-based approach. By facilitating communication among medical practitioners, the platform allows for second opinions and helps to minimize diagnostic errors. It also supports seamless patient follow-up, ensuring that healthcare providers can deliver comprehensive care experiences.
Cleara Biotech B.V. develops compounds for selectively eliminating senescent and senescent like cancer cells. The company develops FOXO4 based anti senescence drugs for countering chemotoxicity and therapy resistant cancer cells. Cleara Biotech B.V. is based in Utrecht, the Netherlands.
At XENO we believe biology speaks biology best. Many foundational problems in diagnostics and bioengineering are solvable if biology could just do more of the work. But current biotech isn’t smart enough. We are interested in changing the status quo by systematizing biologic units and constructing modular composition rules. We are a team of engineers and biologists with specialized expertise and common system goals.
SiPhox Inc. is a company based in Cambridge, Massachusetts, specializing in the design and manufacture of disposable testing kits for COVID-19 and other diseases. Founded in 2020, SiPhox offers a handheld testing device that utilizes advanced technology to perform RNA, DNA, and protein testing. The company's testing kits incorporate multiplexing of RNA, antibody, and antigen tests on a single silicon photonic chip, enhanced by plasmon resonance and silicon photonic resonator readout. This innovative approach allows users to safely conduct tests for various diseases in both point-of-care and at-home settings, using disposable SiPhox Biosensor cartridges and the SiPhox PROBE.
Rejuvenation Technologies Inc. develops nucleoside-modified telomerase reverse transcriptase messenger ribonucleic acid to extend telomeres for human health extension. It offers cell therapies, which includes tissue engineering, tissue and cell transplants, skin grafts, immunotherapy, and regeneration medicine. The company was incorporated in 2016 and is based in Mountain View, California.
Zoe Biosciences is developing a platform for longevity therapeutics with a focus on the apelin axis to allow for the targeting of aging directly, enabling healthcare providers to prevent or delay most chronic diseases.
Juvena Therapeutics, Inc., a biopharmaceutical company, develops protein-based tissue rejuvenation therapeutics for elderly people. Its products are used for treatment of sarcopenia, wound healing, and neural regeneration. Juvena Therapeutics, Inc. was founded in 2017 and is headquartered in San Mateo, California.
NOVOS is a brand focused on longevity supplements aimed at promoting longer and healthier lives. The company develops science-based products that are designed to slow the aging process and enhance overall well-being. Its offerings include a range of healthcare drink supplements enriched with anti-aging and longevity properties, featuring ingredients such as nicotinamide riboside, magnesium, fisetin, and pterostilbene. These products are formulated with antioxidants and other functional components that support DNA repair and mitigate DNA damage. By addressing these critical health aspects, NOVOS aims to help consumers improve their mental health, wellness, and overall lifespan.
Intervene Immune specializes in developing innovative immunotherapies and diagnostics aimed at regenerating the thymus and addressing age-related decline in the immune system. The company focuses on techniques that reverse thymic involution and epigenetic aging, thereby enhancing the body's ability to produce T cells from bone marrow-derived cells. These T cells play a critical role in the immune response against foreign invaders such as bacteria and viruses, as well as in attacking tumors. By providing methods for immune system regeneration, Intervene Immune aims to improve the health and resilience of older individuals' immune systems.
Operator of a drug platform company intended to create biomimetic therapeutics and synthetic compounds that mimic and improve upon biomolecules. The company's platform effectively destroys viruses, bacteria, fungi, and some cancers, while avoiding healthy cells in human tissues and animal studies, where compounds imitate key components of the immune system, enabling healthcare professionals to treat formerly untreatable conditions.
Equity Crowdfunding in 2021
Occuity Ltd is a company based in Reading, United Kingdom, that focuses on the research, design, and manufacture of non-contact optical instruments used in healthcare diagnostics and monitoring. Established in 2019, Occuity develops a range of handheld devices, including pachymeters, pupillometers, and keratometers, which facilitate precise measurements of the eye. These instruments operate by directing light into the eye and analyzing the reflected signals, enabling optometrists and ophthalmologists to obtain critical eye measurements. Additionally, Occuity's technology can assist in monitoring general health conditions, such as diabetes and Alzheimer's disease, through eye assessments.
Provider of personal prevention care services intended to cater to older adults with heart failure and other chronic conditions. The company offers a range of services including local nurse practitioners, pharmacy services, monitoring, and recording vitals, providing older adults with preventive care, and helping them to change their habits and take meaningful preventive actions to maintain independence, reduce hospitalizations, and extend safe aging in place.
VasoDynamics is a developer of cancer-preventative therapies aimed at improving the standard of cancer care. The company focuses on radioprotection programs that are supported by international patents and grounded in innovative research. By utilizing cost-effective medications, VasoDynamics enables patients and healthcare professionals to mitigate the common side effects associated with cancer treatments. This approach enhances treatment outcomes and significantly improves the quality of life for patients undergoing therapy.
We aspire to be a leading applied research organization in the field of advanced integrated and personalized therapies. With clinics in Europe and US, we work closely with research organizations to execute clinical trials and formulate advanced clinical programs.
Healthy Longevity Guide is an educational platform for medical learning. They offer education, webinars, patient handouts, a marketplace, a catalog of medicine, courses, and certification.
HealthyLongevity.cafe is an innovative health-focused café that provides personalized wellness strategies and recipes tailored to individual nutritional needs. Utilizing advanced AI technology, the café offers insights based on behavioral assessments and medical tests, enabling customers to understand their energy levels, sleep quality, and daily demands. The café's offerings include delicious superfoods infused with essential supplements, meticulously designed by healthcare professionals, including physicians and nutritionists, to address specific health requirements. By examining factors such as blood biochemistry, genetics, food intolerances, and microbiome health, HealthyLongevity.cafe ensures that each customer receives a unique wellness plan that promotes longevity. This integrated approach makes healthy eating accessible to everyone, regardless of their location, positioning HealthyLongevity.cafe at the forefront of personalized health and nutrition.
The speed of research and product development is dramatically increasing. Most of that advancement is done by small, new companies - startups. These companies have no capacity to build worldwide distribution channels and the availability of their products is local and very limited. It is not even feasible for health professionals like physicians, clinics or specialized shops to buy directly, often oversee these emerging products. Diagnostic products mostly require sample collection or specialized laboratory preprocessing before shipping. We provide standardized or bespoke solutions for full selling life cycle of longevity products: - Market Research and Recommendations - Local Compliance - Local Brand Creation - Pre-contracted Local Distribution Channels or Direct Customers - Complete Logistics Solution - Sample Collection and Laboratory Processing
Senisca is a senotherapeutics company established in 2020, focused on developing anti-aging oligonucleotide therapeutics. The company aims to provide innovative pharmaceutical treatments for age-related chronic diseases by creating a new generation of oligonucleotide-based interventions. These therapeutics target the underlying mechanisms of aging, restoring the ability of cells to regulate gene expression effectively. By rejuvenating aged cells, Senisca seeks to improve healthspan and address both the diseases and aesthetic manifestations of aging, ultimately enabling individuals to live healthier for longer periods.
Genflow Biosciences PLC is a preclinical biotechnology company focused on developing innovative biological interventions aimed at tackling the effects of aging, potentially slowing or halting the aging process and reducing the incidence of age-related diseases and thereby increasing life span. The company is also focused on longevity and the development of therapies to counteract the effects of aging and diseases associated with age.
Provider of a health and wellness services intended to bring a uniquely balanced, scientific, and personalized approach to weight loss. The company's program offers an AI-driven mobile application with programs based on individual goals, unique biology, specific lifestyle considerations, customized support, digital coaching, and resources, helping users change their metabolic state and ultimately change their lifestyles to enable sustained weight loss and long-term wellness.
Vesttoo Ltd is a company based in Tel Aviv, Israel, that specializes in artificial intelligence-driven financial risk management solutions. Founded in 2018, it offers a comprehensive platform designed for insurers, reinsurers, and pension funds, focusing on the transfer of various risks, including general insurance, mortality, and longevity risks, to capital markets. Vesttoo employs advanced proprietary algorithms to create precise risk models and forecasts, facilitating the structuring and placement of deals. By integrating technology into risk transfer processes, the company provides clients with affordable and strategic options for managing their risk exposure, while offering investors opportunities for high-yield investments with low correlation to traditional market risks. This innovative approach aims to enhance liquidity and streamline the interaction between insurance and capital markets, creating a more accessible and efficient risk management landscape.
Operator of a drug discovery biotech company intended to address complex diseases of aging. The company's technology is focused on the clinical development of small molecule drugs targeting mitochondrial ion channels addressing a constellation of complex disease states, and preclinical assets based upon selected and lead compounds for rare and high prevalence kidney diseases as well as various cancers, enabling researchers to get improved drugs for a broad range of diseases as well as other disorders associated with metabolic dysfunction.
Operator of a preclinical research company in mitochondrial transfusion intended to prevent and stop Alzheimer's, Parkinson's, and other age-related diseases. The company leverages technology to provide mitochondrial therapy to accelerate healing and reduce frailty for the aged, speed the healing of wounded soldiers, or combat aging itself, enabling patients to better combat aging-related diseases.
Repair Biotechnologies, Inc. is a biotechnology company based in Syracuse, New York, established in 2018. The company focuses on developing innovative gene and protein therapies aimed at reversing age-related conditions such as immunosenescence and atherosclerosis. It addresses critical issues like thymic atrophy and the associated decline in immune function, which are prevalent in aging populations. By targeting the root causes of age-related diseases, Repair Biotechnologies aims to enhance the health span of individuals and improve overall well-being. The company employs a cholesterol-degrading platform to tackle localized accumulations of excess cholesterol, promoting safe and effective treatments for related medical conditions.
Yolife’s mission is to help 1 million people add 15 healthy years to their lives. This science-based app is designed to make life-extending easy and accessible. Therefore, Yolife creates an AI-driven personalized health program based on each user's specific areas of improvement: nutrition, exercise, sleep, stress and social life. The app’s lifestyle suggestions are fueled by more than 300 scientific studies and constantly updated.
iamYiam is an award-winning personalised preventive health partner. On the backdrop of a $8 trillion global health care cost, $6.1 trillion is purely linked to preventable lifestyle diseases. Combining big health data, Ai, genetics and academic research (covering >2.5 million clinical trial subjects), iamYiam delivers the world’s first personalised health plan that is to be executed through the platform’s curated products & services. With a team of scientists, mathematicians, engineers and clinicians, iamYiam and its Foundation are focused on Science-backed preventive health and customised care that fast tracks one’s progress towards optimal health – from childhood to retirement. Its mission is to enhance the health & quality of life of 1 billion people by 2025. iamYiam has already been acknowledged as a leader in health & technology and was awarded the Seal of Excellence for Research and Innovation by the European Commission, selected by the UK government to represent UK healthcare innovation globally, selected by NHS Digital as innovation partner, appointed affiliate of Cornell University’s Healthy Futures Institute, named strategic partner for M&C Saatchi, selected as innovation partner for Deloitte and strategic partner for illumina, recently partnered with Oxford University for Ai Research and with Warwick University for Healthcare Research, invited as member of the Global Alliance for Genomics & Health and member of the Prince’s Trust Business in the Community. iamYiam’s clients include users in 32 countries and a range of global organizations including private equity firms, brokers, insurers, biotech firms, law firms, consulting firms, tech companies, start-ups, charities and schools. iamYiam was shortlisted for the upcoming UK Angel Investment Awards 2018 and appeared in many publications such as the FT, The Times, Forbes, Marie Claire, etc.
Animal Biosciences, Inc. is a biopharmaceutical company dedicated to enhancing the health and longevity of companion animals. The company focuses on developing innovative compounds and treatments specifically designed for veterinary application, aiming to alleviate the effects of aging and improve overall well-being. By leveraging advanced technologies to monitor the physical activity and behavior of pets, Animal Biosciences seeks to create proven solutions that can prolong youth and extend the lifespan of animals. This approach not only benefits pet owners but also addresses the growing need for effective animal healthcare solutions.
Developer of a healthy longevity platform combining single-cell genomics and transcriptomics for aging diagnostics and therapeutics. The platform generates diagnostics reports for clinics and provides insights into drug repurposing candidates, enabling advancements in aging therapeutics and cell therapy quality control.