Acelyrin is a late-stage clinical biopharmaceutical company dedicated to delivering innovative treatment options to patients. The company specializes in identifying, acquiring, and accelerating the development and commercialization of promising drug candidates. By leveraging its expertise, Acelyrin aims to advance transformative medicines that can significantly improve patient outcomes.
ArsenalBio is a programmable cell therapy company focused on creating effective and accessible immune cell therapies, particularly for cancer patients. Established in 2019, the company integrates advanced technologies, including CRISPR-based genome engineering, synthetic biology, and machine learning, to revolutionize the discovery and development of immune cell therapies. ArsenalBio employs a comprehensive research and development approach to produce multifunctional T-cell therapies, utilizing the precise insertion of large synthetic DNA sequences. The company's mission is to enhance the efficacy and safety of immune cell therapies while reducing costs for providers and expanding access for patients. Through its innovative framework, ArsenalBio aims to significantly improve treatment outcomes for a broader patient population.
Sinogen Biopharma is a biotechnology company dedicated to connecting China's innovative drug development with the pharmaceutical market in the United States. The company specializes in the licensing and development of bacterial carrier-based biological anti-tumor drugs aimed at treating malignant tumors, particularly in the area of metastatic tumors and rare diseases. By focusing on the creation of innovative anti-cancer therapies, Sinogen Biopharma seeks to address the needs of both domestic and international pharmaceutical markets.
Neuron23, Inc. develops and manufactures medicines for genetic disorders using advanced artificial intelligence technology and genetics. Founded in 2018 and headquartered in South San Francisco, California, with an additional office in Munich, Germany, the company focuses on creating therapeutics for neurological diseases, including Parkinson's and Alzheimer's, as well as immunological disorders. By leveraging recent advancements in human genetics alongside its AI-enabled drug discovery and biomarker platforms, Neuron23 aims to provide innovative treatments for patients suffering from these debilitating conditions, enhancing their quality of life through targeted and effective therapies.
Electra Therapeutics is a clinical-stage biotechnology company focused on developing therapies that target signal regulatory proteins (SIRP) for treating immunological diseases and cancer. The company has one program in clinical development and two additional preclinical programs. Its lead product candidate, ELA026, is a monoclonal antibody designed to target SIRP on the surface of myeloid and T cells, effectively depleting pathological immune cells. ELA026 is currently being investigated for secondary hemophagocytic lymphohistiocytosis (sHLH), a severe hyperinflammatory condition for which no approved treatment exists.
Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Berkeley, California, specializing in the development of cell therapies for serious autoimmune diseases. Founded in 2018, Kyverna employs advanced T cell engineering and synthetic biology technologies to target and eliminate autoreactive immune cells, addressing the root causes of inflammatory diseases. The company is advancing its therapeutic platform with product candidates such as KYV-101, an autologous CD19 CAR T-cell therapy, and KYV-201, an allogeneic version utilizing the same chimeric antigen receptor. Through these innovative approaches, Kyverna aims to provide effective treatments and potential cures for patients suffering from autoimmune conditions.
Acelyrin is a late-stage clinical biopharmaceutical company dedicated to delivering innovative treatment options to patients. The company specializes in identifying, acquiring, and accelerating the development and commercialization of promising drug candidates. By leveraging its expertise, Acelyrin aims to advance transformative medicines that can significantly improve patient outcomes.
Recludix pharma is a developing platform to discover potent and selective inhibitors of challenging protein targets. The platform approach integrates custom generated DNA-encoded libraries, massively parallel determination of structure-activity relationships, and a proprietary screening tool to ensure selectivity.
Expansion Therapeutics is a drug discovery and development company pursuing the vast potential of small molecule medicines for RNA-mediated diseases.
3T Biosciences, Inc. is an immunotherapy company established in 2017 and based in Menlo Park, California. The company focuses on developing innovative treatments for cancer and other T-cell-mediated diseases by utilizing synthetic biology and machine learning technologies. Its approach involves discovering novel targets for drug development, which aims to enhance the effectiveness of cancer therapies. Through its research and development efforts, 3T Biosciences is committed to providing healthcare professionals with advanced treatment options for patients facing cancer-related illnesses.
Capsida is a biotechnology company focused on developing targeted gene therapies for monogenic and sporadic disorders affecting both the central nervous system and other areas of the body. The company utilizes a proprietary adeno-associated virus (AAV) engineering platform, which creates capsids specifically designed to target particular tissues and cells within affected organs. This advanced approach not only aims to enhance the efficacy of the therapies by ensuring they reach the intended sites of action, but also minimizes the impact on non-target tissues, thereby improving patient health outcomes in the treatment of life-threatening genetic disorders.
Dantari is a biotechnology company focused on developing innovative medicines for the treatment of serious diseases, including cancer and conditions affecting the central nervous system. The company utilizes a pharmaceutical platform that emphasizes the research and development of both small and large molecule therapeutics capable of crossing the blood-brain barrier. Dantari's advanced technology features a higher drug-to-antibody ratio than traditional antibody-drug conjugates (ADCs), allowing for tunable release of therapeutic payloads and the delivery of larger payloads. This approach aims to enhance efficacy and expand the therapeutic potential of its treatments, ultimately improving patient health and providing meaningful medical advancements.
Neuron23, Inc. develops and manufactures medicines for genetic disorders using advanced artificial intelligence technology and genetics. Founded in 2018 and headquartered in South San Francisco, California, with an additional office in Munich, Germany, the company focuses on creating therapeutics for neurological diseases, including Parkinson's and Alzheimer's, as well as immunological disorders. By leveraging recent advancements in human genetics alongside its AI-enabled drug discovery and biomarker platforms, Neuron23 aims to provide innovative treatments for patients suffering from these debilitating conditions, enhancing their quality of life through targeted and effective therapies.
Neuron23, Inc. develops and manufactures medicines for genetic disorders using advanced artificial intelligence technology and genetics. Founded in 2018 and headquartered in South San Francisco, California, with an additional office in Munich, Germany, the company focuses on creating therapeutics for neurological diseases, including Parkinson's and Alzheimer's, as well as immunological disorders. By leveraging recent advancements in human genetics alongside its AI-enabled drug discovery and biomarker platforms, Neuron23 aims to provide innovative treatments for patients suffering from these debilitating conditions, enhancing their quality of life through targeted and effective therapies.
Acelyrin is a late-stage clinical biopharmaceutical company dedicated to delivering innovative treatment options to patients. The company specializes in identifying, acquiring, and accelerating the development and commercialization of promising drug candidates. By leveraging its expertise, Acelyrin aims to advance transformative medicines that can significantly improve patient outcomes.
Kyverna Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Berkeley, California, specializing in the development of cell therapies for serious autoimmune diseases. Founded in 2018, Kyverna employs advanced T cell engineering and synthetic biology technologies to target and eliminate autoreactive immune cells, addressing the root causes of inflammatory diseases. The company is advancing its therapeutic platform with product candidates such as KYV-101, an autologous CD19 CAR T-cell therapy, and KYV-201, an allogeneic version utilizing the same chimeric antigen receptor. Through these innovative approaches, Kyverna aims to provide effective treatments and potential cures for patients suffering from autoimmune conditions.
Tmunity Therapeutics, based in Philadelphia and incorporated in 2015, is a bio-therapeutics company focused on developing innovative immunotherapies for cancer, infectious diseases, and autoimmune disorders. The company specializes in engineering T cells, utilizing novel T Cell Receptor (TCR) technologies, regulatory T cells (Treg), and universal engineered T cell platforms to enhance the activation and direction of T cells in vivo. Tmunity's proprietary methodologies allow for the activation, expansion, and genetic engineering of T cells derived from peripheral blood, cord blood, and tumors. The founding team comprises experts in T-cell biology, manufacturing, regulatory affairs, and clinical development, boasting a strong track record in conducting safe and effective cell and gene therapy trials. Additionally, Tmunity's manufacturing capabilities support multi-center clinical studies across various therapeutic areas, positioning the company to deliver next-generation personalized immunotherapies.
ArsenalBio is a programmable cell therapy company focused on creating effective and accessible immune cell therapies, particularly for cancer patients. Established in 2019, the company integrates advanced technologies, including CRISPR-based genome engineering, synthetic biology, and machine learning, to revolutionize the discovery and development of immune cell therapies. ArsenalBio employs a comprehensive research and development approach to produce multifunctional T-cell therapies, utilizing the precise insertion of large synthetic DNA sequences. The company's mission is to enhance the efficacy and safety of immune cell therapies while reducing costs for providers and expanding access for patients. Through its innovative framework, ArsenalBio aims to significantly improve treatment outcomes for a broader patient population.
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