WRF Capital

WRF Capital, founded in 1981 and based in Seattle, Washington, is a venture capital firm that focuses on supporting innovative research and early-stage companies in the life sciences, information technology, and physical sciences sectors. As the venture investment arm of the Washington Research Foundation, WRF Capital collaborates with entrepreneurs, research institutions, other investors, and industry partners to transform promising ideas into successful businesses within Washington. The firm is dedicated to fostering advancements in enabling technologies and driving economic growth through strategic investments in groundbreaking research and development.

Tom Cable

Co-Founder, Private Investor and Board Member

William Canestaro

Managing Director

Past deals in Seattle, WA

AdaptX

Series A in 2021
AdaptX operates a healthcare data analytics platform that focuses on delivering automated analytics to frontline clinical staff. Founded in 2016 and based in Seattle, the company emerged from Seattle Children's Hospital and serves hospitals and surgery centers. Through its innovative solutions, AdaptX empowers medical leaders and clinicians to access and analyze data effectively, enabling them to enhance clinical and workflow outcomes. This approach not only improves patient care but also helps reduce costs, thereby transforming clinical operations within the healthcare sector.

Outpace Bio

Series A in 2021
Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety. It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacy and safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.

ThruWave

Seed Round in 2020
ThruWave specializes in millimeter wave imaging technology, catering to various commercial and industrial sectors such as robotics, construction, and quality control. Founded in 2017 and based in Seattle, Washington, the company offers low-cost sensors that leverage patent-pending radar signal processing and GPU-accelerated image reconstruction techniques. ThruWave's technology enhances operational efficiency by allowing construction professionals to visualize the internal structures of walls, ceilings, and floors, thereby reducing risks and expediting workflows. Additionally, its solutions support inventory verification, shipment confirmations, and detection of packaging issues, enabling clients to automate processes such as counting contents and identifying damaged or missing items.

WiBotic

Series A in 2020
WiBotic Inc. specializes in wireless charging and power optimization solutions primarily for robotic systems, including aerial, mobile, and underwater vehicles. Founded in 2014 and based in Seattle, the company offers a range of products such as wireless charging systems, onboard chargers, transmitters, antenna coils, and integrated options. Additionally, WiBotic provides battery intelligence and fleet management software designed to enhance the operational efficiency of robotic fleets, maximizing battery life and reducing charging and maintenance costs. Its technology enables automatic detection of robots or drones, facilitating seamless charging as they approach the wireless platform. WiBotic's solutions are characterized by their safety, reliability, scalability, and ease of implementation, making them suitable for various industrial applications.

Membrion

Series A in 2020
Membrion, Inc. is a company based in Seattle, Washington, that specializes in the manufacture and commercialization of advanced membranes for filtering molecules. Founded in 2016 as a spin-out from the University of Washington, Membrion's technology is designed to operate under various challenging conditions, including extreme temperatures and pH levels, as well as in vacuum and biologically sensitive environments. The membranes are primarily utilized in applications such as flow batteries, water purification systems, fuel cells, and pharmaceuticals. The company has received financial support from numerous organizations, including the Murdock Charitable Trust and the National Science Foundation, which has facilitated its transition from research to commercial product. Membrion's innovative approach focuses on providing clients with durable and cost-effective membranes made from silica gel, contributing to improved efficiency in industrial wastewater treatment and other applications.

AnswerDash

Seed Round in 2015
AnswerDash, Inc. provides Website contextual answer services. It enables companies to provide selection-based, self-service, point-and-click contextual answers on their Websites, Web applications, and mobile experiences to their customers where they need them, whether on desktop or mobile platforms. AnswerDash, Inc. was formerly known as Qazzow, Inc. and changed its name to AnswerDash, Inc. in May 2014. The company was founded in 2012 and is based in Seattle, Washington. As of June 23, 2020, AnswerDash, Inc. operates as a subsidiary of CloudEngage, Inc.

FlexMinder

Series A in 2014
FlexMinder, Inc. develops enterprise software solutions aimed at private health exchanges, health carriers, and third-party administrators. The company focuses on automating the healthcare reimbursement process, streamlining the management of medical spending and flexible spending account claims. By aggregating healthcare information from multiple sources, FlexMinder offers online tools that simplify the reimbursement process for users. Founded in 2011 and based in Seattle, Washington, FlexMinder gained recognition by participating in the TechStars incubator program and secured $1.4 million in Series AA financing in 2013 to support its growth. As of January 2017, FlexMinder operates as a subsidiary of Jelleyvision Lab Inc.

Mirador Biomedical

Series B in 2011
Mirador Biomedical is a company focused on developing and manufacturing innovative physiological pressure measurement devices. By collaborating with experienced medical professionals and scientists, the company aims to create cost-effective solutions that enhance the safety and accuracy of various medical procedures. Their product offerings include devices designed for compass vascular access, lumbar puncture, compartment pressure measurement, thoracentesis, and vascular access lock applications. Through these advancements, Mirador Biomedical seeks to provide vital physiological feedback, helping to reduce doubt and uncertainty during common medical interventions.

Omeros

Series E in 2007
Omeros Corporation is a Seattle-based biopharmaceutical company engaged in the discovery, development, and commercialization of small-molecule and protein therapeutics. The company focuses on large-market and orphan indications, particularly targeting inflammation, complement-mediated diseases, and disorders of the central nervous system. Omeros offers OMIDRIA, a product used during cataract surgery in the United States. Its clinical pipeline includes narsoplimab, a monoclonal antibody in Phase III trials for various conditions, including hematopoietic stem-cell transplant-associated thrombotic microangiopathy and immunoglobulin A nephropathy. Other clinical programs involve treatments for opioid and nicotine addiction, as well as compulsive disorders. Preclinical efforts include developing therapies for paroxysmal nocturnal hemoglobinuria and exploring a range of G protein-coupled receptors for various disorders. Founded in 1994, Omeros is committed to addressing significant unmet medical needs through its innovative therapeutic approaches.

Farecast

Series C in 2007
Farecast is a fare-prediction service founded in 2003 that helps travelers decide when to purchase airline tickets. The company utilizes a sophisticated analytical engine that examines 175 billion points of historical airfare data to predict future price movements, claiming a success rate of 70-75% for its predictions. This allows users to determine whether to buy a ticket now or wait for potential fare drops. In addition to airfare predictions, Farecast has expanded its offerings to include hotel deals, displaying results from various travel search sites on a map with pricing information. The platform highlights overpriced hotels in blue and those with attractive pricing in red, helping users identify the best deals. Farecast distinguishes itself in a competitive market by focusing on predictive analytics, asserting that it is the only company capable of forecasting future airfare prices.

VLST Corporation

Series B in 2006
VLST Corporation is a privately held biotechnology company that has developed a novel and streamlined approach to speed the development of effective therapeutics for the treatment of inflammatory and autoimmune diseases. The VLST platform uses novel bioinformatics and state-of-the-art proteomics, to identify viral genes whose protein products function as immunomodulatory agents. The resulting product candidates will be either human homologues to these virulence factors or monoclonal antibodies that mimic the function of the virulence gene products. This approach allows for the efficient identification of high quality, pre-validated drug targets for the treatment of autoimmune and inflammatory disorders. The Company's technology has identified potential product candidates for the treatment of disorders such as multiple sclerosis, lupus, psoriasis, rheumatoid arthritis and diabetes.

Uptake Medical

Series A in 2006
Uptake Medical specializes in developing innovative medical technologies aimed at treating lung diseases. The company's flagship product, InterVapor™, is an endoscopic lung volume reduction therapy designed specifically for individuals with severe emphysema. This unique approach leverages the body’s natural healing processes and does not introduce any foreign materials into the lungs. Clinical studies have shown that InterVapor™ can lead to significant improvements in patients' breathing function, exercise capacity, and overall quality of life.

Amnis Corporation

Venture Round in 2001
Amnis Corporation engages in the development, manufacture, and marketing of cell analysis systems for the imaging and analysis of cells in flow. It provides ImageStream, an instrument that combines the functionalities of microscopy and flow cytometry in a single platform for various applications in drug discovery, basic biomedical research, and diagnostics. The company also offers upgrades for ImageStream system to add additional functionality, including violet and red lasers, and an extended depth of field technology (EDF) option. In addition, it provides IDEAS, a cell image analysis software that is used for the quantitative analysis of cell images, as well as for the evaluation of image-based data in various cell populations. Further, the company provides a calibration reagent for the operation of ImageStream system that allows the instrument to track flow rate and core position; and a sheath solution for the functioning of ImageStream system. Its systems are used in apoptosis, immune synapse analysis, nuclear translocation, leukocyte classification, cell cycle analysis, cell morphology analysis, intracellular molecular trafficking, surface markers co-localization, and gene expression quantitation applications. The company offers its products to academic, biotechnology, and pharmaceutical customers. Amnis Corporation was founded in 1998 and is headquartered in Seattle, Washington.
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