Three Leaf Ventures

Three Leaf Ventures is a venture capital firm based in Denver, Colorado, founded in 2014. It specializes in investing across various stages, from seed to late-stage startups, with a particular focus on healthcare sectors such as telemedicine, healthcare technology, genomics, and digital health. The firm typically invests between $0.5 million and $2 million per deal, although it is open to investing as little as $0.1 million in startups and up to $5 million in select opportunities. As a subsidiary of The Broe Companies, Inc., Three Leaf Ventures emphasizes long-term partnerships, providing entrepreneurs with not only financial support but also access to a robust network of resources and industry connections.

15 past transactions

Beddr

Series A in 2018
Beddr is a health technology company based in Mountain View, California, that focuses on improving sleep quality through an integrated digital approach. Founded in 2016 by experienced digital health entrepreneurs, Beddr combines clinical-grade sleep sensors with predictive analytics to deliver personalized insights and recommendations for users. By capturing and correlating various data points, the company aims to help individuals identify and address the underlying causes of their sleep issues. Supported by investors such as Three Leaf Ventures and the Stanford-StartX Fund, Beddr is dedicated to enhancing the quality of life for millions by providing innovative solutions to sleep-related challenges.

Gamelynx

Venture Round in 2018
Gamelynx Inc. is a Canadian company based in Waterloo that specializes in developing a digital gaming platform. This platform enables users to engage in board games and card games without the need for physical components. Additionally, Gamelynx focuses on creating team-based competitive mobile games and video games that aim to make eSports accessible across various platforms. Their offerings include cross-platform games that can be played on Windows, Mac, iOS, and Android, allowing gamers to connect and compete with others regardless of the device they are using.

Biolinq

Series A in 2017
Biolinq Inc. is a San Diego-based company that specializes in developing skin-applied electronic sensors designed to analyze body fluids for health monitoring. Founded in 2012 and originally known as Electrozyme LLC, Biolinq aims to enhance the experience of individuals with diabetes by providing a more affordable and pain-free alternative to conventional continuous glucose monitoring (CGM) systems. The company's platform features minimally invasive electrochemical biosensors capable of measuring multiple analytes, including glucose, ketones, and lactate. This innovative technology not only facilitates easier blood glucose monitoring but also delivers actionable insights into metabolic health, significantly improving the quality of life for patients managing diabetes.

CirrusMD

Series A in 2017
CirrusMD Inc. operates a healthcare communication platform that enhances patient access to medical care in the United States. Founded in 2012 and based in Denver, Colorado, the CirrusMD platform allows patients to securely message doctors, send images, schedule video consultations, and access their health information at any time. The service emphasizes a text-first approach, enabling seamless communication between patients and local physicians through HIPAA-compliant channels. By facilitating direct messaging and video chats, CirrusMD aims to revolutionize the way patients receive frontline medical services, making healthcare more accessible and convenient.

Cohero Health

Series A in 2016
Cohero Health, Inc. is a digital respiratory health company that focuses on improving the management of asthma and chronic obstructive pulmonary disease (COPD). Founded in 2012 and based in New York, the company offers a proprietary connected health platform that combines sensor-based technology with a mobile application. This platform includes the BreatheSmart app, which provides customized medication reminders, records inhaler usage, and tracks lung function, symptoms, and environmental conditions over time. Cohero Health's product suite features mSpirometer lung function sensors and HeroTracker, a Bluetooth-enabled inhaler tracker that monitors both control and rescue medications. Additionally, BreatheSmart Connect serves as a Software-as-a-Service solution for remote patient monitoring and communication, enhancing coordination between patients and healthcare providers. By utilizing these tools, Cohero Health aims to improve medication adherence and overall health outcomes for individuals with respiratory conditions.

Hint Health

Seed Round in 2016
Hint Health Inc. develops a membership management platform for direct care providers. Its platform comprises tools that streamline membership administration and billing for providers and their patient, employer, and health plan clients. The company's offers plans such as essentials, plus, pro, and enterprise. The company was incorporated in 2013 and is headquartered in San Francisco, California.

CirrusMD

Seed Round in 2016
CirrusMD Inc. operates a healthcare communication platform that enhances patient access to medical care in the United States. Founded in 2012 and based in Denver, Colorado, the CirrusMD platform allows patients to securely message doctors, send images, schedule video consultations, and access their health information at any time. The service emphasizes a text-first approach, enabling seamless communication between patients and local physicians through HIPAA-compliant channels. By facilitating direct messaging and video chats, CirrusMD aims to revolutionize the way patients receive frontline medical services, making healthcare more accessible and convenient.

Genomenon

Seed Round in 2016
Genomenon, Inc. is a software development company based in Ann Arbor, Michigan, that specializes in tools for genetic diagnosis and research. Founded in 2014, it provides a suite of diagnostic and discovery software that enables physicians, pharmaceutical companies, and researchers to quickly and accurately identify disease-causing variants from genomic-sequencing datasets. The flagship product, GENOMENON, automates the analysis of next-generation sequencing data, facilitating faster decision-making in cancer diagnosis and treatment, as well as in the study of inheritable diseases. By improving the efficiency of genomic interpretation, Genomenon aims to enhance patient outcomes and advance genetic research.

Cohero Health

Seed Round in 2015
Cohero Health, Inc. is a digital respiratory health company that focuses on improving the management of asthma and chronic obstructive pulmonary disease (COPD). Founded in 2012 and based in New York, the company offers a proprietary connected health platform that combines sensor-based technology with a mobile application. This platform includes the BreatheSmart app, which provides customized medication reminders, records inhaler usage, and tracks lung function, symptoms, and environmental conditions over time. Cohero Health's product suite features mSpirometer lung function sensors and HeroTracker, a Bluetooth-enabled inhaler tracker that monitors both control and rescue medications. Additionally, BreatheSmart Connect serves as a Software-as-a-Service solution for remote patient monitoring and communication, enhancing coordination between patients and healthcare providers. By utilizing these tools, Cohero Health aims to improve medication adherence and overall health outcomes for individuals with respiratory conditions.

Naked Labs

Seed Round in 2015
Naked Labs is a Silicon Valley-based startup focused on3D scanning, computer vision, and human-centered design. It uses infrared light to capture a 3D body model, which is visualized on the Naked app. The company was founded in 2015 and is headquartered in Redwood City, California.

inui

Series B in 2015
inui Health is a consumer medical diagnostics company located in Silicon Valley, focused on making medical-grade information accessible to individuals at any time and place. The company has developed a cloud-based diagnostic platform that operates in a mobile environment, allowing consumers to access their health information easily. Their products aim to assist users in detecting health complications early, monitoring their overall health, and sharing pertinent information with healthcare providers for timely interventions. The first product to be launched is the inui In-Home Urine Analysis test system, which offers immediate lab test results for patients and physicians. These innovations empower consumers to manage their health and monitor various conditions, including kidney function and urinary tract infections.

CirrusMD

Seed Round in 2015
CirrusMD Inc. operates a healthcare communication platform that enhances patient access to medical care in the United States. Founded in 2012 and based in Denver, Colorado, the CirrusMD platform allows patients to securely message doctors, send images, schedule video consultations, and access their health information at any time. The service emphasizes a text-first approach, enabling seamless communication between patients and local physicians through HIPAA-compliant channels. By facilitating direct messaging and video chats, CirrusMD aims to revolutionize the way patients receive frontline medical services, making healthcare more accessible and convenient.

Invitae

Series F in 2014
Invitae is a genetic information company focused on integrating genetic testing into routine medical practice to enhance healthcare quality worldwide. It specializes in genetic diagnostics for hereditary disorders, offering a comprehensive service that consolidates a wide array of genetic tests into one platform, ensuring faster turnaround times and lower costs compared to traditional single-gene tests. Invitae's test offerings cover various hereditary conditions, including cancers, neurological disorders, cardiovascular diseases, pediatric and metabolic disorders. The company aims to make genetic testing more affordable and accessible, develop a secure infrastructure for genome management, and foster a global community for sharing genetic information to advance scientific research and medical practices. By lowering the barriers to obtaining diagnostic genetic information, Invitae seeks to improve healthcare outcomes for millions of individuals.

Hint Health

Angel Round in 2014
Hint Health Inc. develops a membership management platform for direct care providers. Its platform comprises tools that streamline membership administration and billing for providers and their patient, employer, and health plan clients. The company's offers plans such as essentials, plus, pro, and enterprise. The company was incorporated in 2013 and is headquartered in San Francisco, California.

inui

Series A in 2013
inui Health is a consumer medical diagnostics company located in Silicon Valley, focused on making medical-grade information accessible to individuals at any time and place. The company has developed a cloud-based diagnostic platform that operates in a mobile environment, allowing consumers to access their health information easily. Their products aim to assist users in detecting health complications early, monitoring their overall health, and sharing pertinent information with healthcare providers for timely interventions. The first product to be launched is the inui In-Home Urine Analysis test system, which offers immediate lab test results for patients and physicians. These innovations empower consumers to manage their health and monitor various conditions, including kidney function and urinary tract infections.
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