Castle Creek Biosciences

Castle Creek Biosciences, Inc. is a gene therapy company based in Exton, Pennsylvania, that specializes in developing and commercializing personalized gene therapies for rare and serious diseases, particularly those affecting the skin and connective tissue. Founded in 2015, the company utilizes a unique fibroblast technology platform that extracts fibroblast cells from a patient's own skin to create tailored therapies. This approach aims to provide localized treatments that align with the individual biology of each patient, addressing the underlying causes of their conditions. By focusing on diseases with high unmet medical needs, Castle Creek Biosciences seeks to improve the lives of patients suffering from these underserved disorders.

Jeff Aronin

Founder and Chairman

1 past transactions

Fibrocell Science

Acquisition in 2019
Fibrocell Science, Inc., is an autologous cell therapy company focused on the development of innovative products for aesthetic, medical and scientific applications. The fibroblast cell plays a key role in the production of collagen and growth factors which support the skin and other soft tissues; therefore, these cells could play a key role in treating many medical conditions. They have a robust pipeline and clinical programs based on the autologous fibroblast cell. They believe their aesthetic indication is a beachhead for higher value indications. They have a strong base of knowledge and expertise in cell based product development, manufacturing and seeking regulatory approvals. Their focus is to enter clinical programs to treat medical conditions that have an unmet need, helping patients and creating more value per cell.
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