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JumpStart

JumpStart Inc. is a non-profit organization transforming the economic impact of entrepreneurial ventures and the ecosystems supporting their growth. JumpStart’s primary service is intensive entrepreneurial development assistance delivered to Northeast Ohio entrepreneurs leading high potential, early-stage companies. JumpStart also supports the growth and strengthening of Northeast Ohio’s innovation and entrepreneurial ecosystem by securing a continuous stream of resources for entrepreneurs. In doing this work, JumpStart focuses on economic inclusion and activities that increase the success of minority and women entrepreneurs in growing high impact companies. As Northeast Ohio’s entrepreneurial landscape continues to transform, JumpStart collaborates with community and regional leaders nationally to support the startup and development of high growth businesses that have a significant and sustainable impact on the economy.

Ashley Alber

PRINCIPAL, INVESTING

KB

Kevin Berner

Venture Partner

JB

Josh Borstein

Investment Associate

Joshua Borstein

INVESTMENT ASSOCIATE

GC

Greg Carlin

Lead Venture Partner

Hardik Desai

SENIOR PARTNER, INVESTING

Jerry Frantz

CHIEF INVESTMENT and SERVICES OFFICER

JL

Jonathon L. Grimm

Senior Venture Partner

JG

Jon Grimm

CFO IN RESIDENCE

RH

Rem Harris

Senior Partner, Investing

DJ

Duke Jankura

SENIOR PARTNER, FINANCE

DK

Dean Koch

Venture Partner

Ray Leach

CEO

Kevin Mendelsohn

Venture Partner, Investment Associate

Lorne Novick

SENIOR PARTNER, SERVICES and DEAL FLOW MANAGEMENT

Lee Poseidon

Senior Partner, Entrepreneurial Services and Investing

Gloria Ware

Principal

153 past transactions

Max Endoscopy

Seed Round in 2010
MAX Endoscopy designs and manufactures innovative endoscopic accessory devices that fill unmet needs in the field of Gastrointestinal (GI) endoscopy. We develop devices and instruments that are novel and yet practical and cost effective, providing opportunities for physicians in gastroenterology and related medical specialties to provide better treatment.

Wiretap

Series A in 2017
Aware is a cloud intelligence platform that adopts the latest advancements in cognitive computing, artificial intelligence, and behavioral analytics to amplify enterprise value by monitoring the social graph. They harness the power of their platform’s insights into human behavior and interactivity to create great value for the enterprise. They have only built a fraction of what they imagined and now they are looking for incredibly talented people to help us achieve their aspirational vision.

ReadySet Surgical

Series A in 2020
Readyset Surgical LLC develops cloud-based dashboard software solution that coordinates surgical vendor inventory. It also offers RS Analyze, a solution to help hospitals grade vendor performance and identify off-contract implant purchases with real-time data allowing them to take corrective actions; and delivers 24/7 technology support services. The company serves hospital staff and vendor representatives. Readyset Surgical LLC was incorporated in 2014 and is based in Cincinnati, Ohio.

S4 Medical

Series A in 2021
Sotera is a medical device company focused on innovative solutions for cardiac procedures. The company’s initial product is a solution for reducing complications to the esophagus during catheter ablation treatment for atrial fibrillation.It is commercializing a novel medical device designed to protect the esophagus during catheter ablation procedures.

Movable

Seed Round in 2013
Movable offers a wrist-worn activity monitor that measures all movement. Its product MOVband is a simple and fun wrist-worn activity monitor that measures all movement, not just steps. The company’s primary targets are corporate and school-based wellness programs.

MAR Systems

Seed Round in 2007
MAR Systems was founded in 2006 to develop a patented, proprietary process to remove mercury, selenium, arsenic, and other metal contaminants from water. Headquartered in Cleveland, Ohio, MAR Systems’ Sorbster media technology assists companies in achieving the most strict EPA standards by chemisorbing contaminants and creating a non-hazardous disposal option. MAR Systems’ process has been co-developed with the EPA and is quickly becoming an industry standard. The company was founded in 2006 and is based in Cleveland, Ohio.

Segmint

Venture Round in 2011
Segmint empowers financial institutions and financial technology providers to easily understand and leverage data, interact with customers, and measure results. Derived from billions of transactions, Segmint provides the fastest and most accurate customer insights through advanced data tagging, categorization, and contextualization. Our insights enable all functions of an organization to inform strategies including competitive analysis, risk, marketing, customer experience, and product innovation.

OnShift

Seed Round in 2009
OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare. Our suite of products for hiring, scheduling and employee engagement drives quality care, lower costs and higher performance by empowering providers to staff consistently and efficiently. Intuitive design, predictive analytics and customer success management are why thousands of post-acute care and senior living organizations rely on OnShift.

ENDOTRONIX

Seed Round in 2010
Endotronix is a developer of hemodynamic monitoring technologies to help detect worsening heart failure earlier than ever before. The company's platform includes a cloud-based disease management data system and outpatient hemodynamic management with a breakthrough implantable wireless pulmonary artery sensor for early detection of worsening heart failure. It was founded in 2007 and is based in Lisle, Illinois.

Aria Analytics

Series B in 2007
Aria Analytics, Inc. develops and commercializes analytical technology to characterize liquids for healthcare and industrial applications. The company’s Aria technology is used for testing of raw materials, manufacturing process, contaminated products, counterfeit drugs and finished goods. Aria Analytics also offers subassembly systems and software for automated analytical diagnostics. It serves specialty chemical, healthcare, pharmaceuticals, and counterfeit product markets. The company was founded in 2003 and is based in Cleveland, Ohio. Aria Analytics, Inc. is a former subsidiary of 5iTech, LLC.

orthobrain

Series A in 2022

Wiretap

Series B in 2020
Aware is a cloud intelligence platform that adopts the latest advancements in cognitive computing, artificial intelligence, and behavioral analytics to amplify enterprise value by monitoring the social graph. They harness the power of their platform’s insights into human behavior and interactivity to create great value for the enterprise. They have only built a fraction of what they imagined and now they are looking for incredibly talented people to help us achieve their aspirational vision.

Signal Cortex

Seed Round in 2022
TonDone is the amazingly simple building and facility service software. Frontline employees can manage their assigned work with a single click. Managers get immediate and accurate insights into their complete business operations.
Intelligent Mobile Support provides innovative technology solutions to help you support your sales reps and technicians in the field.

SHARE

Series A in 2022
SHARE Mobility helps professional transportation operators use mobility-as-a-service to reach new customers, automate dispatching, and increase fleet efficiency. Organizations use SHARE Mobility to create mobility-as-a-service programs that connect private and public transit services and makes it easy to schedule and use mobility. We are delivering on mobility-as-a-service's promise to create equitable access to jobs, education, and healthcare. We give organizations the tools to make it possible

Catacel

Seed Round in 2010
Catacel maintains industry-leading expertise in foil-supported reaction materials, including: * Catalysts and sorbents for a wide range of reactions: fuel reforming, hydrogen syngas production, tail gas combustion, catalytic partial oxidation, gas separation * High-temperature, heat exchanging materials for endothermic and exothermic reactions * Foil substrate design, manufacturing, and coating Our unique strengths in those competencies include: * Synthesis and evaluation of high-performance catalytic materials * World-class technology for durable bonding of catalyst and sorbent materials to complex metal foil surfaces * Design and manufacturing of metal foil structures that operate in hostile conditions while providing high-performance heat transfer and heat management * Development of custom prototypes and demonstration systems, to high-volume manufacturing and global supply

OnStation

Seed Round in 2021
OnStation builds an app that provides instant jobsite location, access to plans and design, and a team communication tool. It features an automatic station finder that empowers the user with the quickest and easiest way to know their location on the job. Their Station Finder feature can be converted to operate from the user's statewide milepost network. This allows OnStation to provide value on the numerous smaller jobs where survey data and project documents might be limited.

Stanton Advanced Ceramics

Seed Round in 2004
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.

Theravasc

Series A in 2010
TheraVasc, Inc., a biotechnology company, develops repurposed drugs for vascular disease markets. It offers TV1001, an oral formulation of sodium nitrite that targets patient populations with poor blood flow to the extremities, such as those with diabetic leg and foot problems, and peripheral artery disease. The company was incorporated in 2009 and is based in Cleveland, Ohio.

Unify Labs

Seed Round in 2022

Inspherion

Seed Round in 2007
Inspherion builds confidence and conviction in critical return on investment (ROI) decisions. Inspherion has helped birth vibrant new offering strategies and hundreds of millions of dollars of new revenue for clients, and helped avoid investments that would have lost more than a billion dollars over time. Inspherion has been helping Fortune 500 companies win and make better technology investments and resource allocation decisions for over a decade. For these companies, Inspherion’s analyses have been worth the investment. Money spent has been returned to profit within weeks in terms of time saved. The analyses continue to return money to the bottom because of the longevity of the reports. This is what gives Inspherion its incredible repeat customer rate.

iGuiders

Seed Round in 2009
iGuiders patent-pending online decision technology helps simplify online product searches & turns web visitors into qualified leads and closed sales. "Half of potential Web sales are lost because visitors simply can't find what they want." (Informationweek.com) The "thinking" help people need to make decisions isn't provided online. Buyers & sellers both lose out. Online search is an independent activity, yet people still want expertise along the way to facilitate quick decision-making. Guiders help online visitors quickly identify what they want, leads them to the exact information they need, and helps them make decisions faster. The Guider technology enables companies to create a series of questions on their product or service which then leads different customers to the specific solution that matches their needs. Qualified leads and metrics are collected from users guided sessions and provided to Guider owners. Guiders complete the search process by picking up where search engines leave off. They take generalized searches and make them personalized and specific. See our demo @ www.iGuiders.com/explore
Embrace Pet Insurance Agency LLC provides pet insurance services in the United States. It offers insurance products for pets, such as puppies, dogs, kittens, and cats for unexpected accidents or illnesses. The company develops Embrace360, a software application that enables veterinary hospitals to integrate pet insurance into their practice. Embrace Pet Insurance Agency LLC was formerly known as Embrace Pet Insurance, LLC and changed its name to Embrace Pet Insurance Agency LLC in December 2006. The company was founded in 2003 and is based in Cleveland, Ohio. As of April 1, 2019, Embrace Pet Insurance Agency LLC operates as a subsidiary of Cleverland Holdings, LLC.

Vitalxchange

Pre Seed Round in 2019
Vitalxchange is a community and marketplace platform to empower patients to take charge of their health by providing them direct access to fast and actionable information from peer experts and professionals. Our community currently serves special needs families. Key areas served: pediatric therapy, Behavior therapy, Occupational therapy, Speech therapy, developmental delays, Special education, Advocacy, Ask an expert, developmental disability, autism, special needs.

SoLo Funds Inc.

Seed Round in 2019
Solo is the community bank redefined where users borrow on their own terms and lend to reap the benefits. SoLo provides the science. SoLo Funds is the leading alternative financial solution providing the fastest loan option to borrowers and option for lenders to obtain significant value. SoLo launched as a unique & proprietary lending marketplace and has since grown to a multifaceted advanced community banking solution powered by individual capital and enabled by insurance, banking products, and dynamic A.I. underwriting.

LifeMedix

Seed Round in 2012
LifeMedix, LLC is developing a hand-held, ultra-portable medical infusion pump. Generating its own electricity in conjunction with a piezoelectric component and battery, the device requires no external electrical power source or battery recharging.

Wizest

Pre Seed Round in 2021

Renalis

Pre Seed Round in 2021
Renalis is a digital health company that develop platforms to improve experiences and outcomes for people with pelvic health conditions. Designed to tackle the challenges in pelvic health management, Renalis platforms increase patient engagement, improve adherence, decrease out-migration, saving providers valuable time and effort.

Wiretap

Series C in 2021
Aware is a cloud intelligence platform that adopts the latest advancements in cognitive computing, artificial intelligence, and behavioral analytics to amplify enterprise value by monitoring the social graph. They harness the power of their platform’s insights into human behavior and interactivity to create great value for the enterprise. They have only built a fraction of what they imagined and now they are looking for incredibly talented people to help us achieve their aspirational vision.

Checkpoint Surgical

Series A in 2009
Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures. The company's flagship product, the Checkpoint Stimulator/Locator is a single-use, hand-held stimulator with a broad range of stimulation parameters that are fully controllable by the surgeon with one hand and capable of eliciting a muscle contraction from stimulating the nerve directly or the tissue surrounding the nerve. The Checkpoint Surgical team continues to develop new and innovative first in class devices to help surgeons achieve better patient outcomes.

EmployStream

Series B in 2020
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

Mezu

Venture Round in 2018
Mezu is a mobile payment app that gives you a private and secure way to give and get money without sharing your personal information. Just like cash, with Mezu, you can conveniently pay, tip, earn and donate safely and for free. Because Mezu believes that what you do with your money is your business. Mezu is now available on iOS and Android in the United States. Sign up and learn more: https://www.mezu.com.

MedCity News

Seed Round in 2012
MedCity News creates content for people who care about health care. It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience. Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand. It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it. Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.

Thermalin Diabetes

Venture Round in 2010
Thermalin hopes to disrupt the $30B insulin/insulin delivery market with a disposable, postage-stamp-sized glucose management system enabled by our first-in-class stabilized, highly concentrated, and ultra-rapid acting insulin. This same new insulin molecule in "ordinary" (U-100) concentration will enable the factory-filling of reservoirs for existing insulin pumps. In addition to this lead program, Thermalin is developing partnerships on no-cold-chain basal and mix insulins and on glucose-responsive insulins.

StreamLink Software

Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.

ReadySet Surgical

Series A in 2020
Readyset Surgical LLC develops cloud-based dashboard software solution that coordinates surgical vendor inventory. It also offers RS Analyze, a solution to help hospitals grade vendor performance and identify off-contract implant purchases with real-time data allowing them to take corrective actions; and delivers 24/7 technology support services. The company serves hospital staff and vendor representatives. Readyset Surgical LLC was incorporated in 2014 and is based in Cincinnati, Ohio.

SPR Therapeutics, LLC

Seed Round in 2011
SPRA Therapeutics is a medical device company that is commercializing pain treatments utilizing its proprietary peripheral nerve stimulation (PNS) products. They are developing a pipeline of neurostimulation pain therapies that will exploit the same physiologic mechanism of action, proprietary technology, and clinical approach. The first product to be commercialized is the SMARTPATCHâ„¢ PNS System, which is a short-term, minimally invasive system that is simple to deliver and can be used for up to 30 days to stimulate electrically a peripheral nerve to relieve pain.

PreEmptive Solutions

Funding Round in 2006
PreEmptive Protection is the #1 choice to harden and shield your apps making them more resistant to data and ip theft, hacking and tampering. Dotfuscator for .NET/Xamarin, DashO for Java/Android and JSDefender for JavaScript provide quick to implement, premium, multilayered in-app protection. They instill passive and active defending capabilities to help protect trade secrets (IP), reduce piracy/counterfeiting, and prevent inspection/tampering of code and sensitive data.

CompanionLabs

Seed Round in 2017
CompanionLabs Systems, Inc. develops an application to analyze, optimize, and automate user’s ad performance. It serves advertisers using Facebook and other social media platforms. The company was incorporated in 2016 and is based in Akron, Ohio.

Anderson Aerospace

Seed Round in 2011
Anderson Aerospace, a Kent, Ohio-based company that designs and manufactures advanced technology satellite antenna systems for aircraft.Anderson Aerospace, LLC was founded to pursue new opportunities in aerospace, advanced manufacturing and satellite communications. Their world class team has 140 years of experience in aerospace with 82 years of experience designing, manufacturing and selling aircraft satellite antenna systems.

Intelligent Mobile Support

Seed Round in 2011
Intelligent Mobile Support provides innovative technology solutions to help you support your sales reps and technicians in the field.

Revenue Conduit

Seed Round in 2016
Revenue Conduit is the leading marketing system for small online retailers, designed to help you automatically convert more visitors into customers and more customers into customers for life.

Wisr Inc.

Seed Round in 2017
Wisr Inc. operates an online platform that enables alumni to guide current students through automated matching, scheduling, and follow up communications. Its platform strengthens the work of career services and alumni relations offices for better career outcomes. The company was founded in 2016 and is based in Rocky River, Ohio.

Axuall

Series A in 2021
Axuall, Inc. provides digital network for verifying identity, credentials, and authenticity to healthcare, insurance, financial services, government, philanthropy, manufacturing, logistics, transportation, security, aviation, and construction sectors. The company was incorporated in 2018 and is headquartered in Cleveland, Ohio.

GenomOncology, LLC

Seed Round in 2012
A venture backed and Cleveland, OH based healthcare technology company, GenomOncology is enabling precision medicine by transforming data into actionable information. We offer the GO Precision Medicine Portfolio - a suite of solutions that addresses the full range of needs for Healthcare Institutions. The portfolio supports technical assay validation and testing, clinical decision support, collaborative decision support for Molecular Tumor Board workflows and analytics for monitoring and discovery – to enable cancer precision medicine.

O2 Regen Tech

Pre Seed Round in 2015
O2 RegenTech LLC is commercializing cost-effective, easy-to-use wound care solutions. Our proprietary, patented technology is used in our initial product offering, OXAID™, as an oxygenating, moist, and antimicrobial dressing to promote and accelerate chronic wound healing.

Enosix, Inc.

Series B in 2018
Enosix, Inc. designs and develops integration solutions between front end platforms and systems applications and products (SAP) system to unlock data and surface business process. The company offers solutions, such as Enosix Connect, integrate SAP/ERP system with cloud based application; Enosix Engage; Enosix Surface, provides real time access to SAP ERP data in sales force without middleware; Enosix Sales, read, create, and modify SAP data from sales cloud; Enosix Sales CPQ, leverage SAP data for pricing and quotes in Salesforce CPQ; and Enosix Sales VC, integrate SAP variant configuration with Salesforce in real time. Enosix, Inc. was incorporated in 2014 and is based in Cincinnati, Ohio.

InSeT Systems

Venture Round in 2008
InSeT Systems LLC is the developer of the patented (Patent #7,400,246) Inertial Sensor Tracking system that dramatically aids rescue efforts in mines. The InSeT System uses miniature inertial sensors, proprietary software, and a wireless mesh radio network to display and record the real-time location of miners working underground. The InSeT System provides unprecedented tracking accuracy – tracking miners within a matter of a few feet – thereby enabling rapid, highly targeted rescue efforts when mining disasters occur.

AMVONET

Seed Round in 2012
AMVONET is a comprehensive e-learning management, collaboration and authoring software suite. AMVONET allows you to create and manage content, assessments, and certificates. You can manage students, their grades, and generate progress reports.

ExpenseBot

Seed Round in 2016
ExpenseBot is a developer of an expense management platform used to make business expense reporting easier. The company's software automates the process of filling out expense reports by pulling in information from calendar apps, e-mail, credit card purchase reports, and even a phone’s GPS software. It’s powered by artificial intelligence software that can remind users to file expense actions like meals or a commute. ExpenseBot was founded in 2013 and is headquartered in Cleveland, Ohio.

Komae, Inc.

Angel Round in 2017
Komae is a communal service sharing platform that exchanges points for favors. Their first version targets the child care market and is live in the app stores with over 12,500 accounts created. Parents create a personalized, trusted social network of friends and the app makes it easy to exchange free time, schedule play dates, and grow a network to swap free child care. Their market expansion strategy includes adding pet sitting, carpooling, elder care...anything people care for. Their brand is built on the principle that it takes a village, in fact Kṓmē (ko'-may) means Village in Greek.

Cryothermic Systems, Inc.

Seed Round in 2012
Cryothermic Systems (formerly Life Core Technologies) is an American medical device firm that develops a series of products to improve patient outcomes by preventing brain damage. Its product Excel Cryo is a device that lowers the temperature of the brain, which can be applied immediately at the onset of neurologic injury. Cryothermic Systems was founded in 2008 and is based in Cleveland, Ohio.

STACK Media

Series A in 2008
STACK exists to inspire and empower the next generation of athletes. Their mission is to bridge the information gap between professional and amateur athletes. They attempt to level the playing field and democratize sport. They believe that every athlete should have the information and tools they need to reach their potential. They are the athlete's partner in achieving their athletic destiny—whether it is to make the team, become a starter, earn a scholarship or go pro. They provide authentic training, nutrition, motivation, skills and gear advice from the best pro athletes and performance experts.

Neuros Medical

Series B in 2012
Neuros Medical, Inc., a neuromodulation company, develops proprietary neurostimulation therapies for unmet needs to patients worldwide. It offers Electrical Nerve Block, a technology for the elimination of chronic pain in various applications, including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine. The company also provides Neuros Altius System, a product that consists of an implantable generator with an integrated rechargeable battery, cuff electrode, and external devices. Neuros Medical, Inc. was incorporated in 2008 and is based in Willoughby Hills, Ohio.

Vlipsy, Inc.

Seed Round in 2017
Vlipsy is a startup that offers users short, conversational video clips from their favorite internet videos to share in their online communication—similar to the way sites like GIPHY provide looping images known as GIFs. However, Vlipsy's clips also feature sound, unlike GIFs, which are silent. Founded in 2017 by Nickless, Co-founder Matt Tew and a team of consumer startup veterans, Vlipsy has quickly gained momentum with users. Meanwhile, the platform's API for developers also makes third-party integration easy for partners including Slack, Skype, Viber, Telegram, Kik and more
Embrace Pet Insurance Agency LLC provides pet insurance services in the United States. It offers insurance products for pets, such as puppies, dogs, kittens, and cats for unexpected accidents or illnesses. The company develops Embrace360, a software application that enables veterinary hospitals to integrate pet insurance into their practice. Embrace Pet Insurance Agency LLC was formerly known as Embrace Pet Insurance, LLC and changed its name to Embrace Pet Insurance Agency LLC in December 2006. The company was founded in 2003 and is based in Cleveland, Ohio. As of April 1, 2019, Embrace Pet Insurance Agency LLC operates as a subsidiary of Cleverland Holdings, LLC.

MedPilot

Seed Round in 2019
MedPilot is a tool designed to make healthcare billings & collections departments more effective and efficient. Our software uses data science and behavioral targeting to recommend patient engagement methods, personalize communications and resolve outstanding balances. MedPilot’s analytics reporting can also increase the productivity of in-house & third party call centers. A Techstars Company

Ayalogic

Series A in 2006
Ayalogic was founded in 2002 and is backed by Draper Triangle Ventures, Early Stage Partners, and JumpStart, Inc. imVOX was created by Ayalogic to revolutionize communication in gaming. Ayalogic also runs the Green-Ear network, and has been providing integrated voice services to indie game developers since 2008.

Delta Plant Technologies

Seed Round in 2006
Delta Plant Technologies produces develops agronomics and processing technologies for the production of natural rubber and fuel ethanol feedstock. Delta Plant Technologies was founded in 2003 and is based in Akron, Ohio, United States.

Synapse Biomedical

Seed Round in 2006
Synapse Biomedical Inc (SBI) was founded in September 2002 to commercialize the NeuRx Diaphragm Pacing System (DPS)® that has been developed over a twenty-year period at Case Western Reserve University and the University Hospitals of Cleveland. The innovative research performed at these institutions has led to significant advances in the state of the art of electrical stimulation for the treatment of chronic respiratory insufficiency.

Banyan Technology

Series A in 2006
Banyan's solution creates and maintains direct and instantaneous connections between clients and their freight carriers. Our focus is to enable collaborative relationships that will make both our customers and carriers operations more efficient and more profitable. Banyan is a completely carrier neutral solution. We focus on moving information between business systems and people. We empower over 27,000 manufacturers, distributors and third party logistics companies to increase profits by making better faster decisions on their freight operations.

Guided Interventions

Seed Round in 2013
Guided Interventions is a Cleveland-based medical device startup Led by CEO Dr. Matthew Pollman, Guided Interventions develops a a fractional flow reserve (FFR) guidewire that is designed to provide an effective way to obtain FFR measurements during coronary catheterization procedures. It is optimized for improved maneuverability and handling.

Banyan Technology

Series B in 2007
Banyan's solution creates and maintains direct and instantaneous connections between clients and their freight carriers. Our focus is to enable collaborative relationships that will make both our customers and carriers operations more efficient and more profitable. Banyan is a completely carrier neutral solution. We focus on moving information between business systems and people. We empower over 27,000 manufacturers, distributors and third party logistics companies to increase profits by making better faster decisions on their freight operations.

Cervilenz

Venture Round in 2011
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Enforcer eCoaching

Seed Round in 2012
Enforcer eCoaching is an email-based health coaching company offering a series of interactive, personalized, high-value wellness programs. These programs produce enduring behavioral and environmental changes, resulting in disease reversal and greatly improved quality and vitality of life for participants.

Nine Iron Innovations

Seed Round in 2006
Nine Iron Innovations provides automated mobile video monitoring systems for golf course contests and events. The company’s product portfolio includes VerishotMobile, a golf shot video monitoring, contest, and marketing program for golf courses, event managers, golf management organizations, and independent representatives; and Sharegolf.com, a social networking site that connects golf courses and golfers, and allows them to view and share videos of their swings with other members. Nine Iron Innovations was founded in 2004 and is based in Ohio, United States.

Talmetrix

Venture Round in 2017
Talmetrix humanizes employee and organizational data to elevate performance and productivity. Through its’ technology, solutions, and services, Talmetrix enables organizations to listen for and respond to the factors influencing the employee experience and organizational performance. Talmetrix captures, connects, and transforms disparate data into relevant insights to improve business decision-making and outcomes.

Logos Energy

Series A in 2007
Logos Energy, Inc. develops alternative energy products using fuel cells and alternative liquid fuels. It also offers novel direct carbon fuel cell technology for the creation, storage, and delivery of electrical power. The company was incorporated in 2004 and is based in Highland Heights, Ohio. It has a facility in Ohio, as well as a research laboratory in St. Louis.

MesoCoat

Seed Round in 2009
MesoCoat, Inc. is a new start-up company that is currently involved in the development of coatings for applications ranging from high-end aerospace applications to coatings for infrastructure such as roads and bridges.
CardioInsight Technologies Inc., a medical device company, develops a non-invasive cardiac mapping system to map electrical disorders of the heart. The company offers ECVUE, a non-invasive mapping system that is based on electrocardiographic mapping platform that combines body surface electrical data with heart-torso anatomical data to provide simultaneous multi-chamber three dimensional (3D) maps of the heart’s electrical activity. Its system uses a single-use disposable multi-sensor vest to capture electrical signals from the body surface; and software to compute and visualize epicardial 3D electroanatomic maps and virtual electrograms from the heart. The company was founded in 2006 and is based in Cleveland, Ohio. As of June 18, 2015, CardioInsight Technologies Inc. operates as a subsidiary of Medtronic plc.

Ayalogic

Venture Round in 2010
Ayalogic was founded in 2002 and is backed by Draper Triangle Ventures, Early Stage Partners, and JumpStart, Inc. imVOX was created by Ayalogic to revolutionize communication in gaming. Ayalogic also runs the Green-Ear network, and has been providing integrated voice services to indie game developers since 2008.

Electron Database

Seed Round in 2009
Electron Database Company (EDC) is a Cleveland, Ohio-based company building advanced software technology designed to dramatically improve the performance of enterprise applications, data warehouses and cloud computing infrastructures. EDC's patented technology is expected to deliver over 40 times faster performance on existing disk-based hardware versus existing database software and over 400 times faster performance on advanced, solid-state based hardware currently in development. Once released, EDC's technology will be the only database that fully leverages multi-core technology, 64-Bit computing, and solid-state memory drives that are expected to transform the hardware market and deliver material gains in energy efficiency.

HF Food Technologies, Ltd.

Seed Round in 2007
HF Food Technologies provides food technologies to enhance food flavor while minimizing fat content. The company’s product portfolio includes Nutrigras, a product that enables the one-to-one replacement of fat in beef, pork, and other related food products. This is addition to the seasonings, coatings, sauces and other food specialties they offer. HF Food Technologies operates retail stores in Chicago, Alabama, Georgia, South Carolina, and Tennessee, as well as an online store. The company was founded in 1981 and is headquartered in Cleveland, Ohio, Unites States.

Checkpoint Surgical

Series A in 2010
Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures. The company's flagship product, the Checkpoint Stimulator/Locator is a single-use, hand-held stimulator with a broad range of stimulation parameters that are fully controllable by the surgeon with one hand and capable of eliciting a muscle contraction from stimulating the nerve directly or the tissue surrounding the nerve. The Checkpoint Surgical team continues to develop new and innovative first in class devices to help surgeons achieve better patient outcomes.

Let's Gift It

Seed Round in 2013
Lets Gift It is an easy, fun and affordable way for friends, family, and coworkers to contribute towards the purchase of a gift for someone special. If you have ever organized or contributed towards a group gift, you know that collecting money, feeling obligated to give, and dealing with long email threads can be a pain. We experienced this pain and set out to build a better way to give as a group. Gift giving is about making someone's day special. Gift giving is not about how much you are able to spend. These two principals helped shape the product vision for Lets Gift It. We focused our efforts on creating a product that was easy to use, while making it affordable and fun for a folks who all have a connection to the recipient to give as a group. Lets Gift It is built on cutting edge technology to bring together people from a social graph, who for many different reasons, may not have otherwise been compelled to give a gift to a friend. Imagine its your birthday, and you opened the mail to find a new Callaway Driver generously gifted by the contributions of folks who may not know each other, but all know you. The collective buying power of the group can accomplish a lot of gifting.

VasoLux MicroSystems, LLC

Seed Round in 2009
VasoLux MicroSystems, LLC develops optically based diagnostic devices for surgical and diagnostic procedures. Its diagnostic imaging system helps surgeons to identify later-stage osteoarthritis patients. The company was incorporated in 2005 and is based in Elyria, Ohio.

OnShift

Series A in 2010
OnShift delivers cloud-based human capital management software and proactive services to solve everyday workforce challenges in healthcare. Our suite of products for hiring, scheduling and employee engagement drives quality care, lower costs and higher performance by empowering providers to staff consistently and efficiently. Intuitive design, predictive analytics and customer success management are why thousands of post-acute care and senior living organizations rely on OnShift.

Stanton Advanced Ceramics

Angel Round in 2007
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.

Theravasc

Seed Round in 2010
TheraVasc, Inc., a biotechnology company, develops repurposed drugs for vascular disease markets. It offers TV1001, an oral formulation of sodium nitrite that targets patient populations with poor blood flow to the extremities, such as those with diabetic leg and foot problems, and peripheral artery disease. The company was incorporated in 2009 and is based in Cleveland, Ohio.

Cureo

Pre Seed Round in 2011
Cureo is a web-based collaboration platform purpose-built for nonprofit organizations. The platform allows internal team members to curate and orchestrate collaborations and communications internally AND with all of their external board members, committee members, donors, volunteers, clients, and community partners. This is ideal for teams struggling to get organized and more efficient in this world of app overload and email purgatory. What's unique about Cureo is that its architecture reflects the reality of collaboration in the nonprofit sector and in civic community interactions such as multi-entity task forces working to improve lives and solve critical social problems. The reality is that the vast majority of collaborators are not captive employees of the organizations they contribute to as board members, donors, volunteers, etc. and must interact via multiple channels including email without ever having to log into portal software. Used by some of the most recognized global non-profit entities, Cureo is secure, super easy to use, mobile-friendly and accessible from anywhere.

Freedom Meditech

Series A in 2008
Freedom Meditech is a private, growth-stage medical device company focused on the development and commercialization of first-to-market, non-invasive, ophthalmic medical devices for both chronic disease detection (ClearPath DS-120) and the management of diabetes (I-SugarX). The hallmark of their product portfolio is to provide “free and healthy” alternatives to existing diagnostic tools on the market for the detection, monitoring and management of chronic diseases.

ABSMaterials

Series A in 2010
ABS Materials designs, develops, and delivers solutions for ground, surface, and municipal water contamination. Its solutions include VoC-Eater system, which destroys pharmaceuticals, chlorinated solvents, herbicides, endocrine disruptors, PCBs, dyes, and phenols to outflow clean water; Osorb, a solution to destroy persistent organic pollutants in the groundwater; and Iron-Osorb, an inert sand-like glass used on TCE/PCE/DCE/PCBs. The company’s solutions are used to clean solvents, pesticides, and other persistent organic pollutants from the water, soil, and air. It offers its systems on a rental and long term lease basis. The company was founded in 2008 and is based in Wooster, Ohio with an additional office in Houston, Texas.

Point2 Property Manager

Venture Round in 2008
Point2 Property Manager is the ongoing vision of a group of dedicated real estate software professionals. They spent years leading one of the largest and most successful property management software companies in the country, serving many of the nation's largest apartment owners, managers and real estate institutions.
Prevacept Infection Control is a clinical-stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters.

SoLo Funds Inc.

Convertible Note in 2017
Solo is the community bank redefined where users borrow on their own terms and lend to reap the benefits. SoLo provides the science. SoLo Funds is the leading alternative financial solution providing the fastest loan option to borrowers and option for lenders to obtain significant value. SoLo launched as a unique & proprietary lending marketplace and has since grown to a multifaceted advanced community banking solution powered by individual capital and enabled by insurance, banking products, and dynamic A.I. underwriting.

CoverMyMeds

Seed Round in 2010
CoverMyMeds is a free website and suite of integrated workflow tools that helps physicians and pharmacists complete prior authorization (PA) and other insurance coverage determination forms for any drug and almost all drug plans. PA is the process used by insurance companies to approve or reject prescriptions based on plan formulary. CoverMyMeds makes money by partnering with pharmaceutical manufacturers to improve patient access to branded medications.

StreamLink Software

Venture Round in 2016
StreamLink Software-is a Software-as-a-Service company that develops grant management software for nonprofits and the public sector. Ther grants management solution, AmpliFund, is designed for managing every stage of the grant lifecycle and is at the forefront of automating grant compliance and data standardization in the public sector. It was founded in 2008 and is headquartered in Cleveland, Ohio.

Checkpoint Surgical

Series C in 2015
Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures. The company's flagship product, the Checkpoint Stimulator/Locator is a single-use, hand-held stimulator with a broad range of stimulation parameters that are fully controllable by the surgeon with one hand and capable of eliciting a muscle contraction from stimulating the nerve directly or the tissue surrounding the nerve. The Checkpoint Surgical team continues to develop new and innovative first in class devices to help surgeons achieve better patient outcomes.

SironRX Therapeutics

Venture Round in 2011
SironRX is developing novel therapies exclusively licensed from Juventas Therapeutics and Cleveland Clinic that promote dermal wound repair and reduce scarring. Our lead product is a clinically tested biopharmaceutical that encodes Stromal cell-Derived Factor-1 (SDF-1). SDF-1 is key molecule responsible for activating natural repair processes after tissue injury through prevention of cell death and recruitment of stem cells to the damaged organ. Studies from several laboratories suggest the therapeutic potential of SDF-1 for treatment of a range of wounds such as post-surgical incisions, chronic diabetic ulcers and burns. Development of a cost-effective interactive wound therapy that can be topically administered at the site-of-injury or in chronic wound care settings with the potential to significantly improve function of the damaged tissue will have a major impact on the multi-billion dollar advanced wound management market.

MedCity News

Seed Round in 2010
MedCity News creates content for people who care about health care. It is a solution for media companies and organizations that need content, stakeholders who need actionable information about the medical industry, and advertisers who want to speak to this valuable niche audience. Founded by veteran journalists with both health care reporting and online editorial experience, MedCity News is poised to build an innovative new-media enterprise capable of taking advantage of these converging forces while building a profitable national business and brand. It operates the MedCity News Service, a type of niche wire service focused on the innovation economies in major "medical cities" and states (it has offices in Minnesota and Ohio, but also covers dealflow in the Midwest and Pittsburgh). It also operates MedCityNews.com and a custom content service that creates made-to-order content for anyone that wants it. Its news content is syndicated throughthe Ohio News Network, Akron Beacon Journal, The Kindle, WKYC, the Boston online journal MassDevice and the Zemanta blog aggregator, among others.

Heureka Software

Seed Round in 2017
Heureka provides organizations with tools to help them solve challenges related to managing unstructured data. Its platform makes it fast and easy to search and manage your data across your entire enterprise. It gives you real-time access to unstructured data on network file systems, servers, VM’s, laptops and desktops in order to respond to eDiscovery requests, comply with GDPR & privacy regulations and to automate information governance policies.

Juventas Therapeutics

Seed Round in 2008
Juventas Therapeutics, Inc., a clinical stage biotechnology company, develops non-viral gene therapies that activate natural processes to repair the body. The company focuses on treatment of non-healing wounds in patients with advanced peripheral artery disease. It offers JVS-100, a non-viral gene therapy that expresses stromal cell-derived factor-1 or SDF-1, a naturally occurring signaling protein that has been shown to recruit the body’s own stem cells and promote tissue repair in a range of disease states. Juventas Therapeutics, Inc. was formerly known as AcelleRX Therapeutics, Inc. and changed its name to Juventas Therapeutics, Inc. in April 2009. The company was founded in 2007 and is based in Cleveland, Ohio.

Freedom Meditech

Series A in 2009
Freedom Meditech is a private, growth-stage medical device company focused on the development and commercialization of first-to-market, non-invasive, ophthalmic medical devices for both chronic disease detection (ClearPath DS-120) and the management of diabetes (I-SugarX). The hallmark of their product portfolio is to provide “free and healthy” alternatives to existing diagnostic tools on the market for the detection, monitoring and management of chronic diseases.

S4 Medical

Venture Round in 2020
Sotera is a medical device company focused on innovative solutions for cardiac procedures. The company’s initial product is a solution for reducing complications to the esophagus during catheter ablation treatment for atrial fibrillation.It is commercializing a novel medical device designed to protect the esophagus during catheter ablation procedures.

Cervilenz

Seed Round in 2008
CerviLenz is a new, disposable device that measure vaginal cervical length during a speculum exam. Cervical length is a powerful predictor of preterm birth risk and influences patient management decisions. CerviLenz gives clinicians an immediate, reliable method for measuring the cervix at the point of care. CerviLenz is manufactured and distributed by Cervilenz Inc. headquartered in Chagrin Falls, Ohio.

Laguna Pharmaceuticals

Seed Round in 2010
Laguna Pharmaceuticals Inc. develops and markets drugs and small molecule pharmaceuticals vanoxerine, a therapeutic drug candidate for the treatment of atrial fibrillation (AF) and atrial flutter (AFL). The company was formerly known as ChanRx Corp. and changed its name to Laguna Pharmaceuticals Inc. in February, 2015. Laguna Pharmaceuticals Inc. was founded in 2006 and is based in La Jolla, California.

Monarch Teaching Technologies

Venture Round in 2017
Monarch Teaching Technologies, Inc. develops and markets proprietary software for the treatment of children with Autism and other communication disorders.

Inspiron Logistics LLC

Seed Round in 2009
Inspiron Logistics LLC develops and sells wireless emergency notification systems. Its product wireless emergency notification systems (WENS) is based on text messaging protocols, enables officials to manage and send emergency alerts and information instantly to any user with a profile on their system. The company’s wireless emergency notification systems use text-messaging as the basis for communication during emergency situations. It serves local governments, schools, colleges, companies, and municipalities. The company was founded in 2003 and is based in Akron, Ohio.

Myers Motors

Seed Round in 2009
Myers Motors exists to help you get what you want. What you, and millions like you, want is to change the world for the better by shedding their dependence on oil and putting on a more energy efficient future with electric vehicles that everyone can afford to buy.

Echogen Power Systems

Seed Round in 2007
Echogen Power Systems, LLC develops heat-to-power generation systems. The company’s product captures heat energy and converts into usable power. It offers heat recovery systems for bottom cycling in gas turbines, industrial waste heat recovery, solar thermal, geothermal, and hybrid alternatives to the internal combustion engines. The company also offers heat recovery engines for various power outputs. It serves companies that generate heat as a byproduct of their processes, and others. The company was founded in 2007 and is based in Akron, Ohio. Echogen Power Systems, LLC is a former subsidiary of Cognitek Management Systems Inc.

Wisr Inc.

Seed Round in 2017
Wisr Inc. operates an online platform that enables alumni to guide current students through automated matching, scheduling, and follow up communications. Its platform strengthens the work of career services and alumni relations offices for better career outcomes. The company was founded in 2016 and is based in Rocky River, Ohio.

Telerad Express

Seed Round in 2007
Telerad Express provides remote daytime radiology interpretations in multiple modalities to imaging centers, hospitals, and medical practices. Telerad Express was founded in 2006 and is based in Beachwood, Ohio, United States.

Stanton Advanced Ceramics

Seed Round in 2005
Stanton Advanced Ceramics manufactures industrial ceramics that are used in heating and cooling applications such as in glass or steel making. The company offers proprietary thermally shock resistant, high temperature ceramic matrix composite (CMC) technologies. Stanton Advanced Ceramics was founded in 2001 and is based in Cleveland, Ohio.

Wireless Environment

Seed Round in 2009
Wireless Environment is an innovator of LED lighting technology that optimizes the performance of light-emitting diode (LED) lighting in off-grid lighting applications. Their products and technologies offer unique solutions to shift lighting off-grid and to manage lighting once off the grid.
OrthoHelix Surgical Designs is a medical device company developing a comprehensive line of implants and instruments for use in small bone reconstructive surgery. OrthoHelix is dedicated to being the most responsive device maker in the orthopedic industry. We provide state of the art extremity fixation products that are reliable and easy to use. We enhance surgical outcomes of patients. Our vision is to be an orthopedic company that succeeds by listening to surgeons, giving them what they want and need for safer, faster, easier surgical procedures and improved patient outcomes. We take pride in upholding values of Integrity, Compliance, Dedication, Focus and Speed. Surgeons Speak.

Intellirod Spine, Inc.

Seed Round in 2013
Formerly Known as OrthoData. Intellirod Spine's innovative diagnostic system will allow spine surgeons to accurately assess the success of spinal fusion and eliminate the need for unnecessary exploratory surgery while accelerating patients’ return to work after surgery.
Advanced Materials Technology International LLC (AMTI) is developing and commercializing a line of high-tech, energy-curable, nanoparticle dispersions and coatings. AMTI’s method of producing smaller particles (nanoparticles) and evenly suspending them in liquid medium results in improved color quality, easier application, and improved durability. AMTI produces a solvent-free and energy curable product, which significantly reduces ink and coating drying time and the space requirements needed for air drying large pieces. This unique process addresses environmental concerns, provides superior durability, and can be applied more effectively than standard application methods.

July Systems

Series B in 2004
July Systems is a cloud-based mobile experience and location services platform that connects to a building’s WiFi system. Its purpose is to understand the customer who just walked in the door, how many times they have shopped at this retailer, their loyalty point score, and so forth. This gives the vendor the same kind of understanding about that customer offline as they are used to getting online. It aims to digitize physical spaces and is one of the largest location cloud engines powering global enterprises. Founded in 2001, July Systems is headquartered in Burlingame, California. It was acquired by Cisco in 2018.

Casentric, LLC

Convertible Note in 2013
Casentric, LLC offers CaseXpert, a claims software solution that builds adjuster expertise and optimizes settlement timing and costs. Its solution enables users to create a proprietary approach to investigation, evaluation, and negotiation to identify and attack opportunities at various levels of organization by integrating liability, injury, and medical evaluation components. The company delivers its solution to claims adjusters through the Web using a Software-as-a-Service model or by installing in user’s environment. Casentric, LLC was incorporated in 2009 and is based in Shaker Heights, Ohio.

InSeT Systems

Seed Round in 2010
InSeT Systems LLC is the developer of the patented (Patent #7,400,246) Inertial Sensor Tracking system that dramatically aids rescue efforts in mines. The InSeT System uses miniature inertial sensors, proprietary software, and a wireless mesh radio network to display and record the real-time location of miners working underground. The InSeT System provides unprecedented tracking accuracy – tracking miners within a matter of a few feet – thereby enabling rapid, highly targeted rescue efforts when mining disasters occur.

eFuneral

Seed Round in 2013
eFuneral Solutions, LLC provides online funeral planning services. It enables individuals to compare local funeral homes based on location, price, service options, and service quality; and arranges a burial or cremation funeral service. The company serves customers in Atlanta, Georgia; and Canton, Cleveland, Columbus, and Dayton, Ohio. The company was founded in 2011 and is based in Cleveland, Ohio. eFuneral Solutions, LLC operates as a subsidiary of HLC Ventures, LLC

7SIGNAL

Series B in 2017
7SIGNAL® is a leader in enterprise wireless experience monitoring. 7SIGNAL provides a cloud-based platform that continuously monitors wireless networks and identifies elusive performance issues impacting application performance. By taking the “outside-in” approach to monitoring 7SIGNAL has visibility into the edge of any enterprise or home Wi-Fi network where complex device interaction exists, and user experience matters most. The platform maximizes employee productivity, operational efficiency and network ROI. Designed for the world’s most innovative organizations, educational institutions, healthcare systems and government agencies, the platform is currently deployed at Fortune 500 companies, hospitals and large venues globally. Learn more at www.7signal.com.

Tursiop Technologies

Seed Round in 2009
Tursiop Technologies is developing revolutionary MRI coil devices utilizing proprietary nanotechnology, which will produce higher image quality and faster scan times resulting in a significant boost of the functional capabilities of any installed MRI system. Tursiop-generated imaging enhancements will apply across the entire range of MRI system field strengths, from low-field to high-field systems. Increased diagnostic competency will lead to improved patient outcomes and open the doors to new therapeutic opportunities within the areas of interventional, intra-operative and functional MRI and molecular imaging.

7SIGNAL

Series A in 2015
7SIGNAL® is a leader in enterprise wireless experience monitoring. 7SIGNAL provides a cloud-based platform that continuously monitors wireless networks and identifies elusive performance issues impacting application performance. By taking the “outside-in” approach to monitoring 7SIGNAL has visibility into the edge of any enterprise or home Wi-Fi network where complex device interaction exists, and user experience matters most. The platform maximizes employee productivity, operational efficiency and network ROI. Designed for the world’s most innovative organizations, educational institutions, healthcare systems and government agencies, the platform is currently deployed at Fortune 500 companies, hospitals and large venues globally. Learn more at www.7signal.com.

SpearFysh, Inc.

Pre Seed Round in 2011
SpearFysh, Inc. provides sales force automation tools. It offers SpearFysh, a Web-based application that allows executives, sales managers, and salespeople to manage, share, coach, and search conversations, which have been machine analyzed. The company offers a tablet device that captures field sales interactions real-time; and enables organizations to share, search, and analyze interactions with customers and prospects. SpearFysh, Inc. was incorporated in 2011 and is based in Twinsburg, Ohio.

SironRX Therapeutics

Series A in 2011
SironRX is developing novel therapies exclusively licensed from Juventas Therapeutics and Cleveland Clinic that promote dermal wound repair and reduce scarring. Our lead product is a clinically tested biopharmaceutical that encodes Stromal cell-Derived Factor-1 (SDF-1). SDF-1 is key molecule responsible for activating natural repair processes after tissue injury through prevention of cell death and recruitment of stem cells to the damaged organ. Studies from several laboratories suggest the therapeutic potential of SDF-1 for treatment of a range of wounds such as post-surgical incisions, chronic diabetic ulcers and burns. Development of a cost-effective interactive wound therapy that can be topically administered at the site-of-injury or in chronic wound care settings with the potential to significantly improve function of the damaged tissue will have a major impact on the multi-billion dollar advanced wound management market.

iGuiders

Venture Round in 2010
iGuiders patent-pending online decision technology helps simplify online product searches & turns web visitors into qualified leads and closed sales. "Half of potential Web sales are lost because visitors simply can't find what they want." (Informationweek.com) The "thinking" help people need to make decisions isn't provided online. Buyers & sellers both lose out. Online search is an independent activity, yet people still want expertise along the way to facilitate quick decision-making. Guiders help online visitors quickly identify what they want, leads them to the exact information they need, and helps them make decisions faster. The Guider technology enables companies to create a series of questions on their product or service which then leads different customers to the specific solution that matches their needs. Qualified leads and metrics are collected from users guided sessions and provided to Guider owners. Guiders complete the search process by picking up where search engines leave off. They take generalized searches and make them personalized and specific. See our demo @ www.iGuiders.com/explore

Tursiop Technologies

Seed Round in 2010
Tursiop Technologies is developing revolutionary MRI coil devices utilizing proprietary nanotechnology, which will produce higher image quality and faster scan times resulting in a significant boost of the functional capabilities of any installed MRI system. Tursiop-generated imaging enhancements will apply across the entire range of MRI system field strengths, from low-field to high-field systems. Increased diagnostic competency will lead to improved patient outcomes and open the doors to new therapeutic opportunities within the areas of interventional, intra-operative and functional MRI and molecular imaging.

EmployStream

Series A in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

EmployStream

Seed Round in 2017
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

RSP Tooling

Seed Round in 2008
RSP Tooling is a new technology in the tool and mold making industry that sprays molten steel onto a ceramic negative in order to create production quality molds in less time and with less cost than traditional tool making methods. This process, called the Rapid Solidification Process (RSP) was developed at the Idaho National Engineering and Environmental Laboratory (INEEL) under grants from the U.S. Department of Energy. The RSP Tooling technology is based on six patents with application dates ranging from 1999 to 2004. Currently, the company is producing production and prototype tooling for forging, die casting and plastic injection applications

Milo Biotechnology LLC

Venture Round in 2016
Milo Biotechnology LLC develops therapies to increase muscle strength and prevent muscle atrophy. It develops AAV1-FS344, an adeno-associated virus delivered follistatin protein transgene for multiple muscular dystrophies that is delivered via an adeno-associated virus to achieve long lasting and potent expression in muscle. The company was founded in 2011 and is based in Cleveland Heights, Ohio.

FLX Micro

Venture Round in 2006
FLX Micro manufactures silicon carbide-based microsensors. The company develops its products through silicon carbide deposition and microfabrication technology platform. Its products are used in various applications, such as automotive, energy, environmental, and manufacturing. The company was formerly known as Fiberlead, Inc. FLX Micro, Inc. was founded in 2000 and is headquartered in Cleveland, Ohio.

BoxCast

Seed Round in 2013
BoxCast is a complete video streaming solution that fits in the palm of your hand. Anyone with a video camera can broadcast live video through their website, email, or social media. Viewers tune-in using any Internet connected computer, tablet, or modern smartphone.

Melody Management

Seed Round in 2010
Melody Management LLC provides technology services to manage music careers. The company offers a central music management console, including Melody Music Desk and Melody Card, a pay system for distributed music business. Its professional music management tools helps artists to create consistent Web presence and load music, photos, video, and news that keep their fans informed. The company is based in Columbus, Ohio.

Echogen Power Systems

Series A in 2010
Echogen Power Systems, LLC develops heat-to-power generation systems. The company’s product captures heat energy and converts into usable power. It offers heat recovery systems for bottom cycling in gas turbines, industrial waste heat recovery, solar thermal, geothermal, and hybrid alternatives to the internal combustion engines. The company also offers heat recovery engines for various power outputs. It serves companies that generate heat as a byproduct of their processes, and others. The company was founded in 2007 and is based in Akron, Ohio. Echogen Power Systems, LLC is a former subsidiary of Cognitek Management Systems Inc.

Analiza

Seed Round in 2008
ANALIZA, Inc. is a privately held corporation dedicated to discovering, developing, and commercializing new technologies for the life sciences. ANALIZA provides integrated solutions to key applications in the pharmaceutical, biotechnology and diagnostics industries.

CoverMyMeds

Seed Round in 2011
CoverMyMeds is a free website and suite of integrated workflow tools that helps physicians and pharmacists complete prior authorization (PA) and other insurance coverage determination forms for any drug and almost all drug plans. PA is the process used by insurance companies to approve or reject prescriptions based on plan formulary. CoverMyMeds makes money by partnering with pharmaceutical manufacturers to improve patient access to branded medications.

Prevacept Infection Control

Seed Round in 2007
Prevacept Infection Control is a clinical-stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters.

iGuiders

Seed Round in 2009
iGuiders patent-pending online decision technology helps simplify online product searches & turns web visitors into qualified leads and closed sales. "Half of potential Web sales are lost because visitors simply can't find what they want." (Informationweek.com) The "thinking" help people need to make decisions isn't provided online. Buyers & sellers both lose out. Online search is an independent activity, yet people still want expertise along the way to facilitate quick decision-making. Guiders help online visitors quickly identify what they want, leads them to the exact information they need, and helps them make decisions faster. The Guider technology enables companies to create a series of questions on their product or service which then leads different customers to the specific solution that matches their needs. Qualified leads and metrics are collected from users guided sessions and provided to Guider owners. Guiders complete the search process by picking up where search engines leave off. They take generalized searches and make them personalized and specific. See our demo @ www.iGuiders.com/explore

Caralon Global

Seed Round in 2011
Caralon Global is developing and commercializing an ultra-thin, highly efficient insulation product. The patent-pending technology used to create its Nanotheca® insulation is a uniquely-manufactured vacuum insulated panel that reduces heat transfer better than traditional fiberglass or polyurethane products.

Securus Medical Group

Series A in 2011
Securus Medical Group engages in the development of clinical tools to improve the safety and efficacy of ablation therapy by providing real-time, non-contact, high-resolution tissue temperature monitoring, and mapping products. The company engages in developing real-time, noncontact, thermal mapping systems to determine intrabody tissue temperatures.

Wiretap

Series A in 2018
Aware is a cloud intelligence platform that adopts the latest advancements in cognitive computing, artificial intelligence, and behavioral analytics to amplify enterprise value by monitoring the social graph. They harness the power of their platform’s insights into human behavior and interactivity to create great value for the enterprise. They have only built a fraction of what they imagined and now they are looking for incredibly talented people to help us achieve their aspirational vision.
Embrace Pet Insurance Agency LLC provides pet insurance services in the United States. It offers insurance products for pets, such as puppies, dogs, kittens, and cats for unexpected accidents or illnesses. The company develops Embrace360, a software application that enables veterinary hospitals to integrate pet insurance into their practice. Embrace Pet Insurance Agency LLC was formerly known as Embrace Pet Insurance, LLC and changed its name to Embrace Pet Insurance Agency LLC in December 2006. The company was founded in 2003 and is based in Cleveland, Ohio. As of April 1, 2019, Embrace Pet Insurance Agency LLC operates as a subsidiary of Cleverland Holdings, LLC.

Knotice

Venture Round in 2006
Knotice is a direct digital marketing services and software company headquartered in Akron, Ohio that uses direct digital marketing to provide relevant marketing communications to consumers. Knotice maximizes the ROI of direct digital marketing through process automation, increased relevance, and improved performance. The company pioneered the concept of direct digital marketing – relevant digital communications that are addressed to individual recipients through an email address, Web browser cookie, or a mobile phone number, from a unified marketing database. Knotice’s on-demand software platform, Concentri®, offers simple, powerful ways to create and manage highly targeted, multi-stage communications across mobile, Web, and email. Concentri® is the only software that unifies the vital direct digital marketing channels of mobile, Web, and email. Concentri® provides onsite targeting, testing and optimization, email marketing, mobile marketing, landing page management, and universal profile management all from a unified environment.

Inspiron Logistics LLC

Venture Round in 2008
Inspiron Logistics LLC develops and sells wireless emergency notification systems. Its product wireless emergency notification systems (WENS) is based on text messaging protocols, enables officials to manage and send emergency alerts and information instantly to any user with a profile on their system. The company’s wireless emergency notification systems use text-messaging as the basis for communication during emergency situations. It serves local governments, schools, colleges, companies, and municipalities. The company was founded in 2003 and is based in Akron, Ohio.

EmployStream

Series A in 2019
EmployStream is a hiring workflow automation software platform for staffing companies and other high-volume employers. It also creates high-quality, user-friendly for high-volume employers that automates the hiring and onboarding process for employers. The platform eliminates costly mistakes and delays allowing companies to hire up to 90% faster and at half the cost. The company provides an online hiring platform which offers different features such as paper onboarding, real-time alerting, online application, background checks, applicant pre & interview screening, and verification. EmployStream was founded in 2014 and is headquartered in Cleveland Ohio, USA.

SPR Therapeutics, LLC

Seed Round in 2011
SPRA Therapeutics is a medical device company that is commercializing pain treatments utilizing its proprietary peripheral nerve stimulation (PNS) products. They are developing a pipeline of neurostimulation pain therapies that will exploit the same physiologic mechanism of action, proprietary technology, and clinical approach. The first product to be commercialized is the SMARTPATCHâ„¢ PNS System, which is a short-term, minimally invasive system that is simple to deliver and can be used for up to 30 days to stimulate electrically a peripheral nerve to relieve pain.
CardioInsight Technologies Inc., a medical device company, develops a non-invasive cardiac mapping system to map electrical disorders of the heart. The company offers ECVUE, a non-invasive mapping system that is based on electrocardiographic mapping platform that combines body surface electrical data with heart-torso anatomical data to provide simultaneous multi-chamber three dimensional (3D) maps of the heart’s electrical activity. Its system uses a single-use disposable multi-sensor vest to capture electrical signals from the body surface; and software to compute and visualize epicardial 3D electroanatomic maps and virtual electrograms from the heart. The company was founded in 2006 and is based in Cleveland, Ohio. As of June 18, 2015, CardioInsight Technologies Inc. operates as a subsidiary of Medtronic plc.

Zuga Medical

Seed Round in 2013
Zuga Medical Inc. designs, manufactures, and markets dental implant systems. The company offers implant and abutment products, such as bone level dental implants, implant/abutment fits, platform switching products, and margin rings; implant toolkits; bone grafts; implant motor and hand pieces. It also provides training services. The company sells its products directly and online in the United States, as well as through distributor partners in China. Zuga Medical Inc. was incorporated in 2009 and is based in Beachwood, Ohio with a satellite office in Beijing, China.

HF Food Technologies, Ltd.

Seed Round in 2006
HF Food Technologies provides food technologies to enhance food flavor while minimizing fat content. The company’s product portfolio includes Nutrigras, a product that enables the one-to-one replacement of fat in beef, pork, and other related food products. This is addition to the seasonings, coatings, sauces and other food specialties they offer. HF Food Technologies operates retail stores in Chicago, Alabama, Georgia, South Carolina, and Tennessee, as well as an online store. The company was founded in 1981 and is headquartered in Cleveland, Ohio, Unites States.

Milo Biotechnology LLC

Pre Seed Round in 2012
Milo Biotechnology LLC develops therapies to increase muscle strength and prevent muscle atrophy. It develops AAV1-FS344, an adeno-associated virus delivered follistatin protein transgene for multiple muscular dystrophies that is delivered via an adeno-associated virus to achieve long lasting and potent expression in muscle. The company was founded in 2011 and is based in Cleveland Heights, Ohio.

Thermalin Diabetes

Series A in 2011
Thermalin hopes to disrupt the $30B insulin/insulin delivery market with a disposable, postage-stamp-sized glucose management system enabled by our first-in-class stabilized, highly concentrated, and ultra-rapid acting insulin. This same new insulin molecule in "ordinary" (U-100) concentration will enable the factory-filling of reservoirs for existing insulin pumps. In addition to this lead program, Thermalin is developing partnerships on no-cold-chain basal and mix insulins and on glucose-responsive insulins.

MAR Systems

Seed Round in 2008
MAR Systems was founded in 2006 to develop a patented, proprietary process to remove mercury, selenium, arsenic, and other metal contaminants from water. Headquartered in Cleveland, Ohio, MAR Systems’ Sorbster media technology assists companies in achieving the most strict EPA standards by chemisorbing contaminants and creating a non-hazardous disposal option. MAR Systems’ process has been co-developed with the EPA and is quickly becoming an industry standard. The company was founded in 2006 and is based in Cleveland, Ohio.

7SIGNAL

Series C in 2018
7SIGNAL® is a leader in enterprise wireless experience monitoring. 7SIGNAL provides a cloud-based platform that continuously monitors wireless networks and identifies elusive performance issues impacting application performance. By taking the “outside-in” approach to monitoring 7SIGNAL has visibility into the edge of any enterprise or home Wi-Fi network where complex device interaction exists, and user experience matters most. The platform maximizes employee productivity, operational efficiency and network ROI. Designed for the world’s most innovative organizations, educational institutions, healthcare systems and government agencies, the platform is currently deployed at Fortune 500 companies, hospitals and large venues globally. Learn more at www.7signal.com.

Max Endoscopy

Seed Round in 2010
MAX Endoscopy designs and manufactures innovative endoscopic accessory devices that fill unmet needs in the field of Gastrointestinal (GI) endoscopy. We develop devices and instruments that are novel and yet practical and cost effective, providing opportunities for physicians in gastroenterology and related medical specialties to provide better treatment.

Bezlio

Venture Round in 2018
Bezlio is a SaaS product that allows your mobile workforce to visualize your data and analytics from anywhere, on any device!

Coupad

Seed Round in 2005
CoupAd offers in-store merchandising services and programs for urban consumers and retailers. These enable manufacturers to generate incremental sales within the "price-sensitive urban shopper" segment.

Neuros Medical

Series A in 2017
Neuros Medical, Inc., a neuromodulation company, develops proprietary neurostimulation therapies for unmet needs to patients worldwide. It offers Electrical Nerve Block, a technology for the elimination of chronic pain in various applications, including neuroma/residual limb pain, chronic post-surgical pain, and chronic migraine. The company also provides Neuros Altius System, a product that consists of an implantable generator with an integrated rechargeable battery, cuff electrode, and external devices. Neuros Medical, Inc. was incorporated in 2008 and is based in Willoughby Hills, Ohio.

S4 Medical

Seed Round in 2018
Sotera is a medical device company focused on innovative solutions for cardiac procedures. The company’s initial product is a solution for reducing complications to the esophagus during catheter ablation treatment for atrial fibrillation.It is commercializing a novel medical device designed to protect the esophagus during catheter ablation procedures.

Analiza

Seed Round in 2007
ANALIZA, Inc. is a privately held corporation dedicated to discovering, developing, and commercializing new technologies for the life sciences. ANALIZA provides integrated solutions to key applications in the pharmaceutical, biotechnology and diagnostics industries.

ComSense Technology

Seed Round in 2005
ComSense Technology manufactures high temperature pressure sensors that enable the precision control of diesel, gasoline, and turbine engines. This results in improved fuel efficiency and reduced emissions. ComSense Technology is based in Cleveland, Ohio, United States.

Ayalogic

Seed Round in 2004
Ayalogic was founded in 2002 and is backed by Draper Triangle Ventures, Early Stage Partners, and JumpStart, Inc. imVOX was created by Ayalogic to revolutionize communication in gaming. Ayalogic also runs the Green-Ear network, and has been providing integrated voice services to indie game developers since 2008.