Fractyl Health Inc. is a medical device company specializing in innovative therapies for metabolic diseases, particularly type 2 diabetes and obesity. The company's flagship product, Revita DMR, is a minimally invasive procedure that utilizes hydrothermal ablation to rejuvenate the lining of the duodenum, effectively addressing the underlying causes of these conditions. By focusing on transforming the treatment of metabolic diseases from merely managing symptoms to providing durable, disease-modifying solutions, Fractyl Health aims to significantly improve patient health outcomes. Founded in 2010 and based in Lexington, Massachusetts, the company is committed to developing curative therapies that lessen the burden on patients, healthcare providers, and payers.
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in the development of surgical instruments designed for weight loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products is the Standard Clamp, which assists surgeons in standardizing their techniques to minimize variation, enhance efficiency, and reduce waste during procedures. Additionally, the company's disposable surgical tools complement general-use endoscopic staplers, allowing surgeons to decrease the number of cartridges used in surgeries and ultimately lowering costs. Through these innovations, Standard Bariatrics aims to improve surgical outcomes and streamline the weight loss surgery process.
Fractyl Health Inc. is a medical device company specializing in innovative therapies for metabolic diseases, particularly type 2 diabetes and obesity. The company's flagship product, Revita DMR, is a minimally invasive procedure that utilizes hydrothermal ablation to rejuvenate the lining of the duodenum, effectively addressing the underlying causes of these conditions. By focusing on transforming the treatment of metabolic diseases from merely managing symptoms to providing durable, disease-modifying solutions, Fractyl Health aims to significantly improve patient health outcomes. Founded in 2010 and based in Lexington, Massachusetts, the company is committed to developing curative therapies that lessen the burden on patients, healthcare providers, and payers.
Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.
EBR Systems, Inc. is focused on developing innovative implantable devices for cardiac rhythm management, specifically aimed at treating patients with heart failure and cardiac arrhythmias. The company's flagship product, the Wireless Cardiac Stimulation of the Left Ventricle System, utilizes proprietary wireless technology to provide endocardial pacing for cardiac resynchronization therapy. This approach enhances the heart's pumping efficiency by synchronizing the contractions of the left and right ventricles. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems is committed to advancing therapeutic options for patients suffering from cardiac rhythm diseases through its novel technologies.
Standard Bariatrics is a medical device company based in Cincinnati, Ohio, founded in 2014. The company specializes in the development of surgical instruments designed for weight loss surgeries, particularly laparoscopic sleeve gastrectomy. One of its key products is the Standard Clamp, which assists surgeons in standardizing their techniques to minimize variation, enhance efficiency, and reduce waste during procedures. Additionally, the company's disposable surgical tools complement general-use endoscopic staplers, allowing surgeons to decrease the number of cartridges used in surgeries and ultimately lowering costs. Through these innovations, Standard Bariatrics aims to improve surgical outcomes and streamline the weight loss surgery process.
Fractyl Health Inc. is a medical device company specializing in innovative therapies for metabolic diseases, particularly type 2 diabetes and obesity. The company's flagship product, Revita DMR, is a minimally invasive procedure that utilizes hydrothermal ablation to rejuvenate the lining of the duodenum, effectively addressing the underlying causes of these conditions. By focusing on transforming the treatment of metabolic diseases from merely managing symptoms to providing durable, disease-modifying solutions, Fractyl Health aims to significantly improve patient health outcomes. Founded in 2010 and based in Lexington, Massachusetts, the company is committed to developing curative therapies that lessen the burden on patients, healthcare providers, and payers.
Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.
Shape Memory Medical is a medical device company based in Santa Clara, California, established in 2009. The company specializes in the commercialization of innovative medical devices that utilize shape memory polymer (SMP) materials, originally developed at Texas A&M University and Lawrence Livermore National Laboratory. Shape Memory Medical targets the peripheral vascular, cardiovascular, and neurovascular markets, focusing on minimally invasive endovascular applications. The company has introduced the first FDA-cleared medical device in the vascular sector that employs SMP technology, enhancing the ability of physicians to deliver improved patient care. With a team experienced in SMP foam technology and medical device commercialization, Shape Memory Medical aims to provide advanced therapeutic solutions in its field.
ReThink Medical, Inc. manufactures wrist-worn devices that measure, detect, and notify indicators of worsening heart failures. It detects and notifies worsening conditions of heart and heart failure weeks in advance that allows proper treatment preventing hospitalization. The company was founded in 2010 and is based in San Francisco, California. As of August 11, 2020, ReThink Medical, Inc. operates as a subsidiary of Terumo Corporation.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
Chrono Therapeutics Inc., a digital transdermal drug delivery company, develops SmartStop, a digital nicotine replacement therapy. Its wearable solution tailors the timing and dose sizes of drugs, preempts predictable peak disease, and addiction symptoms with a device. The company was incorporated in 2003 and is based in Hayward, California.
Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.
Arterys Inc. is a technology company specializing in medical imaging analytics, aiming to enhance patient care through innovative solutions. Founded in 2007 and headquartered in San Francisco, California, with additional offices in Calgary and Paris, Arterys offers a cloud-based, AI-powered platform that enables radiologists to visualize and quantify blood flow in the body. Its product lineup includes Cardio AI for cardiac imaging, Lung AI for lung analysis, Liver AI for liver diagnostics, and Chest/MSK AI for detecting various thoracic and musculoskeletal conditions. The platform is fully web-based and FDA-cleared, providing clinicians with tools for automatic and interactive reporting. Additionally, the Arterys PHI Service allows physicians to access patient data remotely, further supporting efficient medical practices.
Twelve manufactures medical devices. It was formerly known as Foundry Newco XII, Inc. The company was incorporated in 2009 and is based in Menlo Park, California.
EBR Systems, Inc. is focused on developing innovative implantable devices for cardiac rhythm management, specifically aimed at treating patients with heart failure and cardiac arrhythmias. The company's flagship product, the Wireless Cardiac Stimulation of the Left Ventricle System, utilizes proprietary wireless technology to provide endocardial pacing for cardiac resynchronization therapy. This approach enhances the heart's pumping efficiency by synchronizing the contractions of the left and right ventricles. Founded in 2003 and headquartered in Sunnyvale, California, EBR Systems is committed to advancing therapeutic options for patients suffering from cardiac rhythm diseases through its novel technologies.
Focal Therapeutics, Inc. is a medical device company based in Aliso Viejo, California, established in 2007 to enhance surgical precision and patient care. The company specializes in the development and marketing of the BioZorb tissue marker, an implantable bioabsorbable device designed to provide three-dimensional radiographic marking of surgical sites, particularly useful in breast cancer surgeries. The BioZorb device is placed by surgeons during tissue removal and aids in imaging, treatment planning, patient positioning, and long-term follow-up. Focal Therapeutics primarily serves surgeons, radiation oncologists, and other healthcare professionals involved in breast cancer treatment. The company operates as a subsidiary of Hologic, Inc. as of October 2018.
SinuSys Corporation designs and develops sinus dilation systems to improve the sinus health of patients. Its product includes Vent-Os, a sinus dilation system, which is intended to provide a means to access the sinus space and to dilate the maxillary sinus ostia and associated spaces in adults for diagnostic and therapeutic procedures. The company’s product pipeline includes Restora, a steroid-eluting spacer that provides mechanical support to healing tissues while eluting an anti-inflammatory steroid. SinuSys Corporation was founded in 2010 and is based in Palo Alto, California.
NanoStim is an early-stage medical device company focused on developing a miniaturized, leadless cardiac pacemaker aimed at reducing complications associated with traditional pacemakers, which affect over 100,000 individuals annually. The company has assembled a highly skilled team of medical device engineers to advance this innovative technology, which is designed for direct implantation in a cardiac chamber without the need for leads. By offering a leadless pacing solution, NanoStim seeks to improve patient outcomes and enhance the safety and effectiveness of cardiac interventions.
NanoStim is an early-stage medical device company focused on developing a miniaturized, leadless cardiac pacemaker aimed at reducing complications associated with traditional pacemakers, which affect over 100,000 individuals annually. The company has assembled a highly skilled team of medical device engineers to advance this innovative technology, which is designed for direct implantation in a cardiac chamber without the need for leads. By offering a leadless pacing solution, NanoStim seeks to improve patient outcomes and enhance the safety and effectiveness of cardiac interventions.
Biomimedica is a medical device company that is pioneering new approaches to joint repair through its proprietary, synthetic cartilage technology. It was founded in 2007 and is based in South San Francisco, California, United States.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
CytoPherx (formerly Nephrion) clinical stage medical device company addressing inflammation-based diseases and conditions. The company’s products are custom configurations of a proprietary selective cytopheresis-based inflammation modulating system.
Crux Biomedical, Inc., established in August 2004 by physicians Tom Fogarty and Frank Arko, focuses on developing innovative medical devices to address the limitations of existing vena cava filters. The company's primary product, the Crux VCF System, serves as a preventive device for pulmonary embolisms, effectively stopping blood clots from reaching the lungs. This system is particularly beneficial for patients at risk of pulmonary embolism who are unable to tolerate blood thinners, providing a vital method for preventing potentially life-threatening clots.
Cianna Medical, Inc., a women’s health company, develops medical technologies for treating breast cancer. The company offers SAVI SCOUT, a wire-free radar localization solution for breast tumor localization; and SAVI Brachy, a solution to deliver a highly-precise dose of radiation only to the tissue where the cancer is likely to reoccur. It also offers BrachyBytes, an e-newsletter that features interviews with experts in breast brachytherapy. The company was incorporated in 2007 and is based in Aliso Viejo, California. As of November 13, 2018, Cianna Medical, Inc. operates as a subsidiary of Merit Medical Systems, Inc.
Sonoma Orthopedic Products specializes in the design, development, and delivery of proprietary orthopedic implants aimed at assisting physicians in the treatment of problematic fractures. The company's innovative WaviBody technology platform facilitates quick and minimally invasive surgical solutions, catering to the needs of active patients. By focusing on advanced orthopedic solutions, Sonoma Orthopedic Products aims to enhance patient recovery and overall quality of care.
Incline Therapeutics is a privately-held specialty pharmaceutical company that focuses on the development of IONSYS, a fentanyl iontophoretic transdermal system designed for adult inpatients needing opioid pain relief following surgery. The company is dedicated to creating a compact, disposable, needleless Patient-Controlled Analgesia system that facilitates the short-term management of postoperative pain. Incline Therapeutics is backed by prominent life science venture capital firms and is led by a management team with extensive experience in the pharmaceutical and medical device sectors.
Reverse Medical is a commercial-stage medical device company focused on revascularizing patients experiencing Acute Ischemic Stroke.
Intuity Medical develops blood glucose monitoring systems for diabetes management. Their POGO Automatic Blood Glucose Monitoring System is the world’s first FDA-cleared automatic, one-step blood glucose meter that combines lancing, blood collection, and analysis into a single 10-test cartridge. It provides a convenient and discreet solution for millions of patients who need to regularly test their blood glucose. The company was founded in 2002 and is headquartered in Fremont, California.
CyberHeart, Inc, a clinical development-stage company, engages in developing non-invasive robotic ablation treatment for cardiac arrhythmias. Its products include CyberHeart System, a proprietary technology and medical software. The company's product is used by radiation oncologists, medical physicists, electrophysiologists, and cardiac surgeons for the treatment of cardiac arrhythmias, such as atrial fibrillation or ventricular tachycardia. The company was founded in 2003 and is based in Mountain View, California. As of April 30, 2019, CyberHeart, Inc operates as a subsidiary of Varian Medical Systems, Inc.
Relievant Medsystems, Inc. is a medical device company focused on addressing chronic axial low back pain through a minimally invasive procedure known as Intracept. This innovative treatment specifically targets the basivertebral nerve, utilizing radio-frequency energy delivered through a small access tube into the vertebral body to ablate the nerve. The procedure is performed under real-time fluoroscopic guidance, ensuring precision and safety. Founded in 2004 and headquartered in Minneapolis, Minnesota, with an additional office in Sunnyvale, California, Relievant aims to provide low-risk therapeutic solutions that significantly improve the quality of life for patients suffering from vertebrogenic low back pain.
Biomimedica is a medical device company that is pioneering new approaches to joint repair through its proprietary, synthetic cartilage technology. It was founded in 2007 and is based in South San Francisco, California, United States.
CyberHeart, Inc, a clinical development-stage company, engages in developing non-invasive robotic ablation treatment for cardiac arrhythmias. Its products include CyberHeart System, a proprietary technology and medical software. The company's product is used by radiation oncologists, medical physicists, electrophysiologists, and cardiac surgeons for the treatment of cardiac arrhythmias, such as atrial fibrillation or ventricular tachycardia. The company was founded in 2003 and is based in Mountain View, California. As of April 30, 2019, CyberHeart, Inc operates as a subsidiary of Varian Medical Systems, Inc.
HeartFlow is a medical technology company that provides new methods of diagnosis and treatment of cardiovascular disease. It offers HeartFlow Analysis, a non-invasive solution available in the United States, Europe, and Japan that helps a physician evaluate whether a patient has significant coronary artery disease based on anatomy and physiology.
The company was started in 2007 and is based in Redwood City, California.