Fidelity

Fidelity Investments is a privately owned investment manager based in Boston, Massachusetts, founded in 1946. The firm offers a wide range of financial services, including individual retirement accounts, 401(k) rollovers, annuities, discount brokerage, and wealth management. It serves a diverse clientele, including individual investors, businesses, financial advisors, and institutions. Fidelity manages equity, fixed income, and balanced mutual funds, investing in public equity and fixed income markets worldwide. The firm conducts in-house research to guide its investment decisions and supports over 32 million clients in achieving their financial goals. Additionally, Fidelity assists more than 22,000 businesses with employee benefit programs and collaborates with over 13,000 financial institutions to provide innovative investment and technology solutions.

Abigail Pierrepont Johnson

Chairman and Chief Executive Officer

Bruce Johnstone

Managing Director and Senior Marketing Investment Strategist

Gerard John McGraw

CFO and Director

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Past deals in Northeastern US

Wasabi

Series D in 2022
Wasabi Technologies, Inc. is a cloud storage provider that offers a fast and cost-effective platform for hybrid and multi-cloud media workflows. The company specializes in hot storage solutions compatible with Amazon S3, delivering average time-to-first-byte speeds of less than 15 milliseconds and ensuring data integrity with active checking. Wasabi's services support a variety of applications, including archiving, backup and recovery, content delivery, and data analytics, catering to sectors such as media and entertainment, education, healthcare, and law enforcement. The company provides a free trial capped at 1 TB of storage and offers flexible pricing options, ensuring that organizations can access secure and reliable data storage without complex pricing structures or unpredictable fees. Founded in 2016 and headquartered in Boston, Massachusetts, Wasabi was previously known as BlueArchive, Inc. before rebranding in 2017.

Castle Creek Biosciences

Venture Round in 2022
Castle Creek Biosciences, Inc. is a gene therapy company based in Exton, Pennsylvania, dedicated to developing and commercializing innovative, personalized gene therapies for rare and serious diseases, particularly those affecting the skin and connective tissue. Founded in 2015, the company aims to address significant unmet medical needs through its specialized pipeline of therapies targeted at these conditions.

Beta Technologies

Series B in 2022
Beta Technologies specializes in the design and development of electric aircraft including advanced flight control and electric propulsion systems, with a focus on clean aviation technology.

Dianthus Therapeutics

Series A in 2022
Dianthus Therapeutics is a biotech company operating in stealth mode. It was founded in 2019 and is based in Waltham, Massachusetts.

Circle

Private Equity Round in 2022
Circle is a financial technology company that leverages blockchain technology to facilitate the sending, receiving, and investing of cryptocurrency assets globally. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle offers a user-friendly online platform that simplifies money transfers and includes services such as Circle Pay for peer-to-peer payments. In addition, the company provides Circle Invest, allowing users to buy and sell cryptocurrencies, and Circle Trade, which operates a trading desk with a substantial liquidity pool for digital assets, averaging $2 billion in monthly trading volume. With significant backing from investors, including notable firms such as Goldman Sachs and Accel Partners, Circle has established a presence in major cities, including Boston, New York, San Francisco, Dublin, London, and Hong Kong. The company is dedicated to accelerating global crypto innovation and adoption through its various financial services.

Coin Metrics

Series C in 2022
Coin Metrics Inc. is an online publisher specializing in blockchain and cryptocurrency data, offering a range of market and network analytics to various industries. Founded in 2017 and based in Cambridge, Massachusetts, the company provides several key products, including the CM Network Data Pro, which delivers historical crypto network data in a detailed format for institutional clients. Additionally, Coin Metrics offers the CM Market Data Feed, a standardized solution for trade, candle, and order book data from multiple exchanges, and CM Reference Rates, which provides fixed pricing for various assets quoted in U.S. dollars. By focusing on transparent and actionable data, Coin Metrics enables stakeholders to better understand and utilize public crypto networks.

LifeMine Therapeutics

Series C in 2022
LifeMine Therapeutics, Inc., a biotechnology company, engages in the genomic discovery of new drug modalities from eukaryotic microbes. It utilizes an integrated genomically-enabled drug discovery platform to discover and develop a pipeline of new drugs from fungi. The company was incorporated in 2016 and is based in Cambridge, Massachusetts with an additional office in New York, New York.

Oddity

Venture Round in 2022
ODDITY is a consumer-tech company that builds and scales digital-first brands to disrupt the offline-dominated beauty and wellness industries. The company owns IL MAKIAGE and SpoiledChild.

SalioGen Therapeutics

Series B in 2022
SalioGen Therapeutics advances in curative genetic therapies using its Exact DNA Integration Technology (EDIT) platform, a mammal-derived genome engineering technology. It is focused on providing durable, safe, and affordable non-viral gene therapies to more patients with inherited diseases. Looking ahead, SalioGen will also explore the EDIT platform’s capabilities to streamline cell therapy, cell engineering, and biologics manufacturing to help an even broader population of patients in need.

EQRx

Post in 2021
EQRx operates as a biotechnology company, focused on re-engineering the process from drug discovery to patient delivery with the goal of offering a market-based solution for the rising cost of medicines. By bringing together stakeholders from across the healthcare system and utilizing the latest advances in science and technology, the company seeks to discover, develop and deliver high-quality, patent-protected medicines more efficiently and cost-effectively than ever before. The company was founded in 2019 and is based in Cambridge, Massachusetts, United States.

Innovid

Post in 2021
Innovid is the only independent omni-channel advertising and analytics platform built for television. Innovid empowers advertisers to personalize, deliver and measure the most innovative advertising experiences on any device and media outlet through a single platform.

Generate Biomedicines

Series B in 2021
Generate Biomedicines, Inc. develops a platform to invent novel antibodies, peptides, enzymes, receptors, and other therapeutic proteins. It offers Generative Biology, a machine learning based solution that learns from all known proteins in order to encode and apply the fundamental principles of how genetic sequences lead to protein structure and function for creating novel protein sequences with optimized therapeutic potential. Its Generative Biology is applied to all protein modalities and generate novel proteins with desired functions and solutions that interact potently and specifically with therapeutic targets. Generate Biomedicines, Inc. was formerly known as Generate Biologics, Inc. and changed its name to Generate Biomedicines, Inc. in March 2020. The company was incorporated in 2018 and is headquartered in Cambridge, Massachusetts.

WeWork

Post in 2021
WeWork, known as The We Company, is a commercial real estate firm that specializes in providing flexible workspaces and office services primarily for entrepreneurs and technology startups. Founded in 2010 and headquartered in New York, the company transforms buildings into dynamic environments that foster creativity, collaboration, and productivity. Its offerings include a variety of workplace solutions such as private offices, shared workspaces, and on-demand access to workstations, catering to diverse member needs. In addition to physical spaces, WeWork provides a range of services through partnerships, enabling members to work, live, and grow. The company also operates WeWork Labs, which supports early-stage startups by providing community and programming to aid their development. With a focus on inclusivity and community, WeWork aims to create an environment where members can thrive and innovate together.

Roivant Sciences

Post in 2021
Roivant’s mission is to reduce the time and cost of developing new medicines for patients and to share those savings with the healthcare system. Roivant does this by building Vants - nimble, entrepreneurial biotech and healthcare technology companies with a unique approach to sourcing talent, aligning incentives, and deploying technology. In addition to its biopharmaceutical subsidiaries, Roivant also builds technology-focused Vants focused on improving the process of developing and commercializing medicines.
Veterinary Emergency Group is the veterinary emergency care, that provides emergency and urgent care for pets, also it open nights, weekends, and holidays to help with all of your pet’s emergencies, provides animals and their families with timely medical care for acute problems at times when they need it.

Skyhawk Therapeutics

Venture Round in 2021
Skyhawk Therapeutics is a provvider of small molecule therapeutics designed to offer therapies that correct RNA expression.The company's therapeutics use proprietary technology that helps the rational design of small molecules that target specific binding pocket regions on RNA, using both sequence and structural specificity, at particular moments in the RNA splicing process, enabling physicians to target diseases driven by a type of RNA mis-splicing called exon skipping.

Cipher Mining

Post in 2021
Cipher Mining is an industrial-scale Bitcoin mining company dedicated to expanding and strengthening the Bitcoin network's critical infrastructure. Its goal is to be the leading Bitcoin mining company in the United States. Cipher Mining aims to leverage best-in-class technology, market-leading power purchase arrangements, and a seasoned, dedicated senior management team to become the market leader in Bitcoin mining.

Laronde

Series B in 2021
Laronde is pioneering a platform that offers a completely novel way of modulating human biology. Endless RNA™ (eRNA), is a uniquely engineered RNA that can be programmed to express diverse proteins inside the body. It is persistent, non-immunogenic, allows for repeat dosing, and offers flexibility in formulation and delivery. Laronde was founded in 2017 by Flagship Labs, the innovation foundry of Flagship Pioneering. The company is rapidly scaling to support the parallel development of multiple programs across many disease areas.

Tango Therapeutics

Post in 2021
Tango Therapeutics, Inc., a biotechnology company, develops cancer drugs based on synthetic lethality. The company uses the genetic principle of synthetic lethality to discover and develop therapies that take aim at driver genes in cancer. It focuses counteracting tumor suppressor gene loss; reversing the ability of cancer cells to evade the immune system; and identifying novel combinations that are more effective than single agent therapy. Tango Therapeutics, Inc. was formerly known as Cancer Combos NewCo, Inc. The company was incorporated in 2014 and is based in Cambridge, Massachusetts.

goPuff

Series H in 2021
goPuff is a Philadelphia-based startup that delivers products like over-the-counter medicine, baby food, and alcohol. goPuff was founded in 2013 by Yakir Gola and Rafael Ilishayev, two Drexel University students with a minivan and a vision to make everyday life a little easier. What started as a snack delivery service quickly grew into a national essential, and food delivery service, and later, in some markets, alcohol delivery. Today, goPuff is the fastest growing delivery service, operating 24/7 in most major markets. goPuff makes sure its customers have everything they need: from quick meals, over-the-counter meds, snacks and drinks to electronics, office supplies, baby and pet essentials, and in some markets, beer, wine, and spirits. Across America, goPuff is known for satiating late-night cravings for Ben and Jerry’s ice cream, Doritos, Red Bull, and, in select markets, White Claw and rescuing those in need of diapers, condoms, and cleaning products. goPuff allows users the joy of browsing the shelves without the hassle of going to the store. It takes seconds to navigate the app and minutes for goPuff’s Driver-Partners to deliver the customer’s needs and wants. goPuff’s strategically located facilities cut out the middleman allowing for a flat fee of $1.95. goPuff’s success has allowed the company to support important causes. In March 2020 goPuff committed to $1 million in orders to hospital workers fighting COVID-19. In May 2020 the company wrote a check for $1 million to match donations to Boys and Girls Clubs. In June 2020 goPuff committed to supporting underrepresented founders in Philadelphia.

GeneDx

Post in 2021
Sema4 is a patient-centered predictive health company dedicated to advancing the diagnosis, treatment, and prevention of disease. With their innovative Sema4 Health Intelligence Platform, they’re using advanced network analysis to build better models of human health and deliver personalized insights for patients.

Hyzon Motors

Post in 2021
HYZON Motors Inc manufactures hydrogen-powered trucks and buses. It offers city and coach buses, medium duty trucks, and heavy duty trucks. The company was founded in 2020 and is based in Honeoye Falls, New York.

Wheels Up

Post in 2021
Wheels Up is a membership-based private aviation company that focuses on reducing the upfront cost to fly privately, providing flexibility, service, and safety. Its mobile app enables members to book flights, manage their accounts, and participate in ride-share opportunities. Its members also have given access to the Wheels Down program. The company was founded in 2013 and headquartered in New York, United States.

Taboola

Post in 2021
Taboola is a content discovery platform that connects users with relevant online content they may not have encountered otherwise. The company serves over 360 billion recommendations to more than 1 billion unique visitors each month on prominent publisher sites, including USA TODAY and Business Insider. Headquartered in New York City, with research and development based in Israel, Taboola also maintains offices in Pasadena, London, and Bangkok. The platform uses an artificial intelligence-driven algorithm to deliver personalized recommendations for news stories, articles, videos, and advertisements across the Open Web. By partnering with various digital properties, Taboola helps publishers, marketers, and agencies enhance user engagement, monetize their traffic, and distribute content to attract high-quality audiences, primarily generating revenue from the United States while also serving markets in Europe and beyond.

Payoneer

Post in 2021
Payoneer Inc. operates a cross-border payments platform designed to facilitate global commerce by connecting businesses, professionals, countries, and currencies. Founded in 2005 and headquartered in New York, the company offers products such as the Global Payment Service, which provides users with local receiving accounts in the United States, European Union, and Japan, allowing for direct local bank transfers. Additionally, Payoneer enables users to receive payments from various integrated partners, including those in freelance, e-commerce, and online advertising sectors. The company also provides mass payout services that assist Indian companies in transferring funds internationally. Serving millions of users across over 200 countries, Payoneer is a trusted partner for numerous prominent corporations, making cross-border payments as straightforward as local transactions.

Perella Weinberg

Post in 2021
Perella Weinberg Partners is an independent, privately-owned financial services firm that provides corporate advisory and asset management services to clients around the world. The Firm has assembled a group of talented and experienced professionals recruited from a wide variety of leading global financial institutions. Launched in 2006, the company is divided into two business units: corporate advisory, which provides services to decision makers in business and government, and asset management, which consists of investment vehicles catering to institutional investors.

Latch

Post in 2021
Latch makes access easier for everyone at a modern building. The company specializes in manufacturing keyless entry security system giving property owners the ability to manage every door in a multi-family building. Moreover, residents can also give access to guests as well as service providers through time-limited access codes. Latch is headquartered in New York, New York, United States.

BarkBox

Post in 2021
BarkBox, created by Matt Meeker, Henrik Werdelin, and Carly Strife, is a subscription e-commerce service designed for dog owners, providing a monthly box filled with toys, treats, and other canine-related products. As the popularity of BarkBox grew, it evolved into Bark & Co, a company focused on enhancing the health and happiness of dogs. Bark & Co operates through several channels, including the subscription services BarkBox and Super Chewer, as well as an e-commerce platform on BarkShop.com. The company also offers wellness products such as BARK Bright and a personalized meal delivery service called BARK Eats. Its business model is primarily driven by the Direct to Consumer segment, which generates most of its revenue from the sale of toys, accessories, and consumables for dogs. Bark & Co aims to meet the diverse needs of dog owners nationwide while fostering a strong connection with their canine companions.

Circle

Private Equity Round in 2021
Circle is a financial technology company that leverages blockchain technology to facilitate the sending, receiving, and investing of cryptocurrency assets globally. Founded in 2013 by Jeremy Allaire and Sean Neville, Circle offers a user-friendly online platform that simplifies money transfers and includes services such as Circle Pay for peer-to-peer payments. In addition, the company provides Circle Invest, allowing users to buy and sell cryptocurrencies, and Circle Trade, which operates a trading desk with a substantial liquidity pool for digital assets, averaging $2 billion in monthly trading volume. With significant backing from investors, including notable firms such as Goldman Sachs and Accel Partners, Circle has established a presence in major cities, including Boston, New York, San Francisco, Dublin, London, and Hong Kong. The company is dedicated to accelerating global crypto innovation and adoption through its various financial services.

ASAPP

Series C in 2021
ASAPP, Inc. develops artificial intelligence-native products designed to address large-scale inefficiencies in customer care and sales processes. Its primary offering is an AI-native platform that empowers agents by providing real-time guidance on communication and actions during customer interactions, whether through phone calls or digital messages. The platform utilizes advanced machine learning models that continuously adapt and learn from each interaction, effectively enhancing agent performance without necessitating extensive training. ASAPP serves major industries, including telecom, financial services, and travel, and has established a global presence with offices in New York, San Francisco, Mountain View, London, Buenos Aires, Ithaca, and Raleigh. Founded in 2014, the company aims to transform the way organizations manage customer engagement through innovative technology solutions.

ASAPP

Series C in 2021
ASAPP, Inc. develops artificial intelligence-native products designed to address large-scale inefficiencies in customer care and sales processes. Its primary offering is an AI-native platform that empowers agents by providing real-time guidance on communication and actions during customer interactions, whether through phone calls or digital messages. The platform utilizes advanced machine learning models that continuously adapt and learn from each interaction, effectively enhancing agent performance without necessitating extensive training. ASAPP serves major industries, including telecom, financial services, and travel, and has established a global presence with offices in New York, San Francisco, Mountain View, London, Buenos Aires, Ithaca, and Raleigh. Founded in 2014, the company aims to transform the way organizations manage customer engagement through innovative technology solutions.

Beta Technologies

Series A in 2021
Beta Technologies specializes in the design and development of electric aircraft including advanced flight control and electric propulsion systems, with a focus on clean aviation technology.

Nuvalent

Series B in 2021
Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer. Leveraging deep expertise in structure-based design, Nuvalent develops innovative small molecules with exquisite target selectivity to overcome resistance, minimize adverse events, and drive more durable responses. It is advancing a robust pipeline with parallel lead programs in ROS1-positive and ALK-positive NSCLC, along with multiple discovery-stage research programs. It was founded in 2017 and is based in Cambridge, Massachusetts.

Wasabi

Series C in 2021
Wasabi Technologies, Inc. is a cloud storage provider that offers a fast and cost-effective platform for hybrid and multi-cloud media workflows. The company specializes in hot storage solutions compatible with Amazon S3, delivering average time-to-first-byte speeds of less than 15 milliseconds and ensuring data integrity with active checking. Wasabi's services support a variety of applications, including archiving, backup and recovery, content delivery, and data analytics, catering to sectors such as media and entertainment, education, healthcare, and law enforcement. The company provides a free trial capped at 1 TB of storage and offers flexible pricing options, ensuring that organizations can access secure and reliable data storage without complex pricing structures or unpredictable fees. Founded in 2016 and headquartered in Boston, Massachusetts, Wasabi was previously known as BlueArchive, Inc. before rebranding in 2017.

Omega Therapeutics

Series C in 2021
Omega Therapeutics, Inc. is a biotechnology company based in Cambridge, Massachusetts, that focuses on developing genomic medicines aimed at curing diseases. Founded in 2016, the company utilizes its proprietary epigenomic programming platform to create Omega Epigenomic Controllers. These innovative controllers are designed to selectively modulate the activity of the human genome, allowing for precise tuning of gene expression to achieve therapeutic effects. By targeting specific cell types, Omega Therapeutics aims to transform human medicine through the direct control of genomic functions, offering potential solutions for a variety of diseases.

goPuff

Series G in 2021
goPuff is a Philadelphia-based startup that delivers products like over-the-counter medicine, baby food, and alcohol. goPuff was founded in 2013 by Yakir Gola and Rafael Ilishayev, two Drexel University students with a minivan and a vision to make everyday life a little easier. What started as a snack delivery service quickly grew into a national essential, and food delivery service, and later, in some markets, alcohol delivery. Today, goPuff is the fastest growing delivery service, operating 24/7 in most major markets. goPuff makes sure its customers have everything they need: from quick meals, over-the-counter meds, snacks and drinks to electronics, office supplies, baby and pet essentials, and in some markets, beer, wine, and spirits. Across America, goPuff is known for satiating late-night cravings for Ben and Jerry’s ice cream, Doritos, Red Bull, and, in select markets, White Claw and rescuing those in need of diapers, condoms, and cleaning products. goPuff allows users the joy of browsing the shelves without the hassle of going to the store. It takes seconds to navigate the app and minutes for goPuff’s Driver-Partners to deliver the customer’s needs and wants. goPuff’s strategically located facilities cut out the middleman allowing for a flat fee of $1.95. goPuff’s success has allowed the company to support important causes. In March 2020 goPuff committed to $1 million in orders to hospital workers fighting COVID-19. In May 2020 the company wrote a check for $1 million to match donations to Boys and Girls Clubs. In June 2020 goPuff committed to supporting underrepresented founders in Philadelphia.

Squarespace

Venture Round in 2021
Squarespace is the all-in-one platform for websites, domains, online stores, marketing tools and scheduling, which entrepreneurs, creatives, and professionals use to build a beautiful presence and maintain their brands online.

ElevateBio

Series C in 2021
ElevateBio, LLC is a holding company based in Cambridge, Massachusetts, that focuses on developing cell and gene-based therapies. Founded in 2017, ElevateBio operates a portfolio of companies dedicated to creating, manufacturing, and commercializing innovative treatments for cancer and viral infections. The company collaborates with leading scientists and inventors to build its portfolio and has established a centralized facility designed to streamline the research and development process. This approach allows ElevateBio to translate scientific advancements in cell and gene therapy into viable medical products, ultimately aiming to provide effective treatments for patients with severe diseases.

Century Therapeutics

Series C in 2021
Century Therapeutics, Inc. is a biotechnology company focused on developing induced pluripotent stem cell (iPSC)-based therapies for cancer treatment. Founded in 2018 and headquartered in Philadelphia, Pennsylvania, the company aims to create allogeneic living drugs that specifically target both hematologic and solid tumors. By utilizing iPSCs, Century Therapeutics can engineer immune effector cells through multiple rounds of cellular modification, producing master cell banks that can be expanded and differentiated for therapeutic use. Their innovative approach incorporates advanced technologies such as CRISPR-mediated gene editing and proprietary chimeric antigen receptors, along with Allo-Evasion technology, which helps prevent rejection by the host immune system. These advancements position Century Therapeutics to enhance the effectiveness and accessibility of cancer treatments.

Butterfly Network

Post in 2021
Butterfly Network designs a medical imaging device that reduces the cost of real-time and three-dimensional imaging and treatment. Jonathan M. Rothberg, Nevada Sanchez, and Tyler S. Ralston founded it in 2011, with its headquarters in Guilford in Connecticut.

Gemini Therapeutics

Post in 2021
Gemini Therapeutics, Inc. is a precision medicine company established in 2015 and based in Cambridge, Massachusetts. The company specializes in developing therapies for patients with dry age-related macular degeneration (AMD) and related rare genetic diseases. Gemini's approach focuses on addressing genetically-defined conditions by creating therapeutic candidates that target specific molecular abnormalities prevalent in patients with significant clinical needs. Their diverse pipeline features a range of innovative treatment modalities, including monoclonal antibodies, recombinant proteins, and gene therapies. The company has secured funding from prominent life science investors and collaborates with academic institutions globally to advance its mission of delivering potentially first-in-class therapeutics.

Billtrust

Post in 2021
Billtrust develops a payment cycle management platform designed to automate every step in the invoice-to-cash process. Its platform accelerates cash flow by automating invoice delivery, invoice payment, and cash application for remarkable cost savings, ease-of-use, and improved customer satisfaction rates, enabling businesses and corporate clients to improve operational efficiency. The company was founded in 2001 and is headquartered in Lawrenceville, New Jersey.

Ikena Oncology

Series B in 2021
Ikena Oncology is dedicated to bringing next generation oncology therapies to patients suffering from cancer. Ikena Oncology are committed to leveraging our unique understanding of the complex biologic pathways that drive the formation and spread of cancers to discover and develop novel, patient-directed therapies. Selecting patients for treatment in clinical studies with biomarkers we develop is at the core of our strategy.
Rush Street Interactive offers online casino and sports betting in the U.S. RSI is the provider of an omnichannel platform for the Land-based Sportsbooks at Rivers Casino Pittsburgh, Rivers Casino Philadelphia, Rivers Casino Schenectady, Rivers Casino Des Plaines, and French Lick Casino (Indiana)

Yumanity Therapeutics

Venture Round in 2020
Yumanity Therapeutics is a biotechnology company dedicated to transforming drug discovery for neurodegenerative diseases linked to protein misfolding. Founded in December 2014 by protein folding expert Susan Lindquist and biotech leader Tony Coles, Yumanity aims to develop innovative, disease-modifying therapies to address critical unmet medical needs in conditions such as Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS). The company leverages proprietary platforms to identify potential therapeutic targets and has made progress in advancing a new chemical lead series specifically for Parkinson’s disease, while also exploring additional compounds for Alzheimer's disease and ALS.

Invivyd

Series B in 2020
Invivyd is a biotechnology company focused on developing advanced antibodies to neutralize SARS-CoV-2, SARS-CoV-1, and other potentially emerging coronaviruses. Founded in 2020 and headquartered in Waltham, Massachusetts, the company aims to create best-in-class therapeutic and prophylactic treatments that surpass the efficacy of existing antibody programs. Its innovative portfolio features multiple non-competing antibodies, each targeting distinct viral epitopes, which is designed to minimize the risk of viral escape. By leveraging cutting-edge antibody discovery technologies, Invivyd seeks to enhance the potency and durability of its antibody candidates, addressing a critical need in the ongoing fight against coronaviruses.

DoubleVerify

Private Equity Round in 2020
DoubleVerify provides online media verification and campaign effectiveness solutions for brand marketers, agencies, advertising networks, demand side platforms, exchanges and digital publishers looking to ensure quality advertising environments, campaign transparency and performance. DoubleVerify validates over 60 billion advertising impressions per month for hundreds of Fortune 500 brands, advertising networks and media platforms. Headquartered in New York City, DoubleVerify’s investors include JMI Equity, Institutional Venture Partners, Blumberg Capital, First Round Capital and Genacast Ventures.

Conformal Medical

Private Equity Round in 2020
Conformal Medical, Inc. is a medical device company focused on developing innovative solutions to prevent strokes in patients with atrial fibrillation (AFib), particularly those with non-valvular AFib. Founded in 2016 and headquartered in Nashua, New Hampshire, the company offers CLAAS Technology, which facilitates the sealing of the left atrial appendage (LAA) through its conformal left atrial appendage closure (LAAC) system. This proprietary technology is designed to adapt to the unique anatomy of each patient, enhancing the effectiveness of LAA closure procedures. By enabling healthcare professionals to treat patients at risk of stroke more effectively, Conformal Medical aims to improve clinical outcomes and save lives.
Cerevel (www.cerevel.com) is a biopharmaceutical company focused on developing drug candidates to treat disorders of the central nervous system (CNS). The company has a portfolio of pre-commercial neuroscience assets, which include three clinical-stage compounds and several pre-clinical compounds designed to target a broad range of CNS disorders including Parkinson’s, Alzheimer’s, epilepsy, schizophrenia and addiction. Headquartered in the Greater Boston area, Cerevel was formed in 2018 through a partnership between Bain Capital and Pfizer.

Wise

Secondary Market in 2020
Wise is a company that specializes in international money transfer services, facilitating easy and low-cost transactions for individuals and businesses. Founded in 2010 and headquartered in London, Wise offers a core money transfer product and a borderless account designed for expats, freelancers, and travelers, which currently holds over £2 billion in deposits. The company also provides a mobile application that allows users to track their transfers and initiate new transactions conveniently. With additional offices in Tallinn and New York, Wise aims to simplify the process of sending money abroad swiftly and affordably.

Invivyd

Series A in 2020
Invivyd is a biotechnology company focused on developing advanced antibodies to neutralize SARS-CoV-2, SARS-CoV-1, and other potentially emerging coronaviruses. Founded in 2020 and headquartered in Waltham, Massachusetts, the company aims to create best-in-class therapeutic and prophylactic treatments that surpass the efficacy of existing antibody programs. Its innovative portfolio features multiple non-competing antibodies, each targeting distinct viral epitopes, which is designed to minimize the risk of viral escape. By leveraging cutting-edge antibody discovery technologies, Invivyd seeks to enhance the potency and durability of its antibody candidates, addressing a critical need in the ongoing fight against coronaviruses.

Vor Biopharma

Series B in 2020
Vor Biopharma, Inc. develops engineered hematopoietic stem cell (eHSC) therapies for cancer patients. It offers VOR33, an eHSC product candidate that is in preclinical development to treat acute myeloid leukemia (AML). The company’s VOR33 eHSCs lacks CD33, a protein that is expressed by AML cancer cells. Vor Biopharma, Inc. was incorporated in 2015 and is based in Cambridge, Massachusetts.

Coin Metrics

Series A in 2020
Coin Metrics Inc. is an online publisher specializing in blockchain and cryptocurrency data, offering a range of market and network analytics to various industries. Founded in 2017 and based in Cambridge, Massachusetts, the company provides several key products, including the CM Network Data Pro, which delivers historical crypto network data in a detailed format for institutional clients. Additionally, Coin Metrics offers the CM Market Data Feed, a standardized solution for trade, candle, and order book data from multiple exchanges, and CM Reference Rates, which provides fixed pricing for various assets quoted in U.S. dollars. By focusing on transparent and actionable data, Coin Metrics enables stakeholders to better understand and utilize public crypto networks.

Castle Creek Biosciences

Venture Round in 2020
Castle Creek Biosciences, Inc. is a gene therapy company based in Exton, Pennsylvania, dedicated to developing and commercializing innovative, personalized gene therapies for rare and serious diseases, particularly those affecting the skin and connective tissue. Founded in 2015, the company aims to address significant unmet medical needs through its specialized pipeline of therapies targeted at these conditions.

Dragonfly Therapeutics

Venture Round in 2020
Dragonfly Therapeutics, Inc. develops drugs to stimulate immune responses against cancer using its platform TriNKET. Dragonfly Therapeutics, Inc. has strategic collaborations with Celgene Corporation and Merck. The company was founded in 2015 and is based in Waltham, Massachusetts.

Clover Health

Venture Round in 2020
Clover Health is a health insurance company that provides Medicare Advantage plans primarily for senior citizens in New Jersey, and it also serves members in several other states, including Arizona, Georgia, Pennsylvania, South Carolina, Tennessee, and Texas. Founded in 2014 and based in San Francisco, Clover Health operates a Preferred Provider Organization (PPO) platform aimed at enhancing the quality of life for its members. The company focuses on preventive care through patient-centered analytics and a dedicated care management team, which helps identify potential health risks and manage chronic diseases. By employing advanced analytics and custom software, Clover Health directs its clinical staff to address care gaps, ultimately aiming to reduce unnecessary healthcare costs while improving health outcomes for its members.

Generation Bio

Series C in 2020
Generation Bio is a genetic medicines company based in Cambridge, Massachusetts, that specializes in developing gene therapies aimed at treating both rare and prevalent diseases. Established in 2016, the company focuses on conditions affecting the liver, retina, skeletal muscle, central nervous system, and oncology. Generation Bio employs an innovative non-viral platform that includes a proprietary high-capacity DNA construct known as closed-ended DNA (ceDNA), a cell-targeted lipid nanoparticle delivery system (ctLNP), and a scalable, capsid-free manufacturing process. This approach allows for the targeted delivery of genetic materials, including large and multiple genes across various tissues, and enables redosable treatments tailored to individual patient needs. By enhancing access to therapies for rare diseases and addressing more common conditions, Generation Bio aims to provide durable and sustainable treatment options for patients throughout their lives.

ACV

Series E in 2019
ACV Auctions, Inc. is a wholesale automotive auction company that operates a mobile platform designed for used-car dealers. Founded in 2014 and headquartered in Buffalo, New York, ACV enables dealers to view, bid on, and purchase car inventory through online auctions. The platform facilitates dealer-to-dealer transactions by allowing users to select desired vehicles and receive alerts on their mobile devices when specific cars become available. Additionally, ACV provides a pricing application for franchise dealers and acts as a closing tool for wholesale buyers to bid on vehicles. This innovative marketplace streamlines the buying and selling process within the automotive industry.

Kitchen United

Series B in 2019
Kitchen United, Inc. is a company that provides food production facilities specifically designed for restaurants and food service providers. Founded in 2017 and headquartered in Pasadena, California, it offers shared commercial kitchen spaces along with business intelligence solutions to support entrepreneurial caterers, pop-ups, mobile food vendors, and start-ups. By providing a turnkey solution, Kitchen United helps restaurant brands expand their operations with minimal risk and investment. Its facilities enable these businesses to efficiently produce food for pick-up and delivery, facilitating their entry into the food delivery market. The company operates locations in major cities across the United States, including Austin, Chicago, Los Angeles, San Francisco, New York City, and Scottsdale.

Wheels Up

Series D in 2019
Wheels Up is a membership-based private aviation company that focuses on reducing the upfront cost to fly privately, providing flexibility, service, and safety. Its mobile app enables members to book flights, manage their accounts, and participate in ride-share opportunities. Its members also have given access to the Wheels Down program. The company was founded in 2013 and headquartered in New York, United States.

THE VOID

Venture Round in 2019
THE VOID, LLC is a company that designs and operates virtual entertainment centers focused on immersive experiences in virtual worlds. Established in 2015 and headquartered in Lindon, Utah, it offers "hyper-reality" experiences that blend virtual reality with interactive real-world environments. The company caters to individuals aged ten and older from diverse backgrounds, allowing them to explore new dimensions and create memorable moments with friends and family. In addition to its headquarters, THE VOID has locations in Anaheim, California; Orlando, Florida; New York City; Dubai, United Arab Emirates; and Toronto, Canada. The founders, Curtis Hickman, James Jensen, and Ken Bretschneider, have aimed to provide unique adventures that engage and entertain guests in a collaborative setting.

CollegeVine

Series B in 2019
CollegeVine provides mentorship, college applications guidance, college essay assistance, tutoring, and test preparation consulting services. The company was formerly known as Admissions Hero LLC and changed its name to CollegeVine in August 2016. CollegeVine was founded in 2013 and is based in Cambridge, Massachusetts.

Karuna Therapeutics

Series B in 2019
Karuna Pharmaceuticals, Inc. engages in development of drugs for the treatment of schizophrenia. The company was incorporated in 2009 and is based in Boston, Massachusetts.

Coin Metrics

Seed Round in 2019
Coin Metrics Inc. is an online publisher specializing in blockchain and cryptocurrency data, offering a range of market and network analytics to various industries. Founded in 2017 and based in Cambridge, Massachusetts, the company provides several key products, including the CM Network Data Pro, which delivers historical crypto network data in a detailed format for institutional clients. Additionally, Coin Metrics offers the CM Market Data Feed, a standardized solution for trade, candle, and order book data from multiple exchanges, and CM Reference Rates, which provides fixed pricing for various assets quoted in U.S. dollars. By focusing on transparent and actionable data, Coin Metrics enables stakeholders to better understand and utilize public crypto networks.

Sweetgreen

Series H in 2018
Sweetgreen, Inc. owns and operates a chain of restaurants in Virginia, Pennsylvania, New York, Maryland, Massachusetts, and District Of Columbia. It also sells gift cards, canvas totes, tees, tanks, beanies, snapbacks, hoodies, and posters online. Sweetgreen, Inc. has a strategic partnership with FoodCorps. The company was founded in 2007 and is based in Culver City, California.

Axcella

Series E in 2018
Axcella Health Inc. is a clinical-stage biotechnology company based in Cambridge, Massachusetts, specializing in the research and development of endogenous metabolic modulators (EMMs) to address complex diseases and enhance overall health. The company focuses on amino acid homeostasis and has identified over 2,000 diseases linked to amino acid imbalances. Axcella has developed a systems pharmacology approach to restore health at the cellular level, leading to a range of clinical-stage candidates targeting conditions such as hepatic encephalopathy, non-alcoholic steatohepatitis, muscle atrophy, and various biological pathways related to blood health. Founded in 2008 and previously known as Newco LS16, Inc., Axcella aims to pioneer innovative treatments that have the potential to significantly impact the therapeutic landscape.

Castle Creek Biosciences

Venture Round in 2018
Castle Creek Biosciences, Inc. is a gene therapy company based in Exton, Pennsylvania, dedicated to developing and commercializing innovative, personalized gene therapies for rare and serious diseases, particularly those affecting the skin and connective tissue. Founded in 2015, the company aims to address significant unmet medical needs through its specialized pipeline of therapies targeted at these conditions.

Butterfly Network

Series D in 2018
Butterfly Network designs a medical imaging device that reduces the cost of real-time and three-dimensional imaging and treatment. Jonathan M. Rothberg, Nevada Sanchez, and Tyler S. Ralston founded it in 2011, with its headquarters in Guilford in Connecticut.

Compass

Series F in 2018
Compass is a real estate brokerage company based in New York City, founded in 2012 by Ori Allon, Robert Reffkin, and Ugo Di Girolamo. The company offers a comprehensive platform for residential real estate agents, equipping them with a suite of cloud-based software tailored for customer relationship management, marketing, and client service. This integrated approach enhances the ability of agents to provide exceptional service to buyers and sellers. In addition to its brokerage services, Compass has developed a mobile app for iOS and Android that facilitates buying, selling, and renting homes across the United States. The company operates primarily within the domestic market.

Fulcrum Therapeutics

Series B in 2018
Fulcrum Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing treatments for patients with genetically defined diseases, particularly in areas of high unmet medical need. Headquartered in Cambridge, Massachusetts, the company is advancing its lead product candidate, losmapimod, which is currently in a Phase 2b clinical trial for facioscapulohumeral muscular dystrophy, a rare and progressive muscle-wasting disorder. Additionally, Fulcrum is developing FTX-6058, a small molecule aimed at increasing fetal hemoglobin levels in patients with sickle cell disease and β-thalassemia. The company is also engaged in drug discovery efforts targeting conditions such as Duchenne muscular dystrophy, Friedreich ataxia, and α-synucleinopathies, as well as other neurological and pulmonary diseases. Fulcrum has established collaborations with Acceleron Pharma to explore biological targets in pulmonary diseases and with MyoKardia for the development of therapies for genetic cardiomyopathies. Founded in 2015, Fulcrum Therapeutics is committed to delivering innovative solutions for patients facing significant health challenges.

Kaleido BioSciences

Series C in 2018
Kaleido Biosciences is a clinical-stage healthcare company with a differentiated, chemistry-driven approach to leveraging the potential of the microbiome organ to treat disease and improve human health. The Company has built a human-centric proprietary product platform to enable the rapid and cost-efficient discovery and development of novel Microbiome Metabolic Therapies (MMT™). MMTs are designed to modulate the metabolic output and profile of the microbiome by driving the function and distribution of the organ’s existing microbes. Kaleido is advancing a broad pipeline of MMT candidates with the potential to address a variety of diseases and conditions with significant unmet patient needs.

Oscar Health

Venture Round in 2018
Oscar Health is a health insurance company that provides individual and family plans, Medicare Advantage, and small group products. Founded in 2012 and headquartered in New York, Oscar Health operates in several states, including New York, Texas, California, New Jersey, Ohio, and Tennessee. The company aims to enhance the healthcare experience by utilizing technology, design, and data to create user-friendly services. Its platform includes a software application that helps users find doctors based on location and ratings. Oscar Health primarily serves individuals and families who do not receive health insurance from their employers.

Generation Bio

Series B in 2018
Generation Bio is a genetic medicines company based in Cambridge, Massachusetts, that specializes in developing gene therapies aimed at treating both rare and prevalent diseases. Established in 2016, the company focuses on conditions affecting the liver, retina, skeletal muscle, central nervous system, and oncology. Generation Bio employs an innovative non-viral platform that includes a proprietary high-capacity DNA construct known as closed-ended DNA (ceDNA), a cell-targeted lipid nanoparticle delivery system (ctLNP), and a scalable, capsid-free manufacturing process. This approach allows for the targeted delivery of genetic materials, including large and multiple genes across various tissues, and enables redosable treatments tailored to individual patient needs. By enhancing access to therapies for rare diseases and addressing more common conditions, Generation Bio aims to provide durable and sustainable treatment options for patients throughout their lives.

Moderna

Series G in 2018
Moderna, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2010. It specializes in the development of therapeutics and vaccines utilizing messenger RNA technology, which instructs cells to produce proteins essential for various biological functions. The company's extensive pipeline includes 40 mRNA development candidates targeting a range of therapeutic areas such as infectious diseases, oncology, cardiovascular diseases, and rare genetic disorders. Moderna gained significant recognition with its COVID-19 vaccine, which was authorized for use in the United States in December 2020. The company maintains strategic partnerships with organizations such as AstraZeneca, Merck & Co., and the Bill & Melinda Gates Foundation, enhancing its research capabilities and manufacturing processes. Additionally, it has research collaborations with esteemed institutions like Harvard University.

Scholar Rock

Series C in 2018
Scholar Rock is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializing in the discovery and development of innovative therapies targeting growth factor signaling in serious diseases. The company’s lead product candidate, SRK-015, is a selective inhibitor of myostatin activation and is currently undergoing Phase II clinical trials for spinal muscular atrophy. Additionally, Scholar Rock is advancing SRK-181, which is in Phase I trials for treating cancers resistant to checkpoint inhibitors. The company employs a proprietary platform to design monoclonal antibodies that selectively modulate the activation of growth factors in disease microenvironments, addressing challenges associated with traditional growth factor inhibition. Scholar Rock is also developing a pipeline of candidates for a variety of conditions, including neuromuscular disorders, cancer, fibrosis, and anemia. Furthermore, the company has a collaboration with Gilead Sciences to explore specific inhibitors of transforming growth factor beta for fibrotic diseases. Founded in 2012, Scholar Rock aims to improve patient outcomes through its targeted therapeutic approach.

Neon Therapeutics

Series B in 2017
Neon Therapeutics is a clinical-stage biopharmaceutical company. It is focused in the field of neoantigen-targeted therapies, dedicated to transforming the treatment of cancer by directing the immune system towards neoantigens. The company's pipeline products are NEO-PV-01, NEO-PTC-01, and NEO-SV-01.

Translate Bio

Series C in 2017
Translate Bio is a clinical-stage biotechnology company based in Lexington, Massachusetts, that focuses on developing messenger RNA (mRNA) therapeutics aimed at treating diseases linked to protein or gene dysfunction. Since its founding in 2011, the company has been working on innovative treatments, including MRT5005, which is currently undergoing Phase I/II clinical trials for cystic fibrosis, and MRT5201, intended for the treatment of ornithine transcarbamylase deficiency. Translate Bio aims to create transformative medicines that address unmet medical needs in rare diseases.

resTORbio

Series A in 2017
resTORbio is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for the treatment of aging-related diseases.The Company develops medicines and therapies to treat aging-related diseases and conditions such as cancer, heart disease, neurodegenerative diseases, and diabetes mellitus. resTORbio serves clients in the State of Massachusetts.

resTORbio

Series B in 2017
resTORbio is a clinical-stage biopharmaceutical company focused on the development and commercialization of novel therapeutics for the treatment of aging-related diseases.The Company develops medicines and therapies to treat aging-related diseases and conditions such as cancer, heart disease, neurodegenerative diseases, and diabetes mellitus. resTORbio serves clients in the State of Massachusetts.

Compass

Series E in 2017
Compass is a real estate brokerage company based in New York City, founded in 2012 by Ori Allon, Robert Reffkin, and Ugo Di Girolamo. The company offers a comprehensive platform for residential real estate agents, equipping them with a suite of cloud-based software tailored for customer relationship management, marketing, and client service. This integrated approach enhances the ability of agents to provide exceptional service to buyers and sellers. In addition to its brokerage services, Compass has developed a mobile app for iOS and Android that facilitates buying, selling, and renting homes across the United States. The company operates primarily within the domestic market.

Wheels Up

Private Equity Round in 2017
Wheels Up is a membership-based private aviation company that focuses on reducing the upfront cost to fly privately, providing flexibility, service, and safety. Its mobile app enables members to book flights, manage their accounts, and participate in ride-share opportunities. Its members also have given access to the Wheels Down program. The company was founded in 2013 and headquartered in New York, United States.

Harmony Biosciences

Venture Round in 2017
Harmony Biosciences Holdings, Inc., a commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients living with rare neurological disorders. Its lead product includes WAKIX (pitolisant) for the treatment of pediatric patients suffering from narcolepsy. Harmony Biosciences Holdings, Inc. was formerly known as Harmony Biosciences II, Inc. and changed its name to Harmony Biosciences Holdings, Inc. in February 2020. The company was founded in 2017 and is based in Plymouth Meeting, Pennsylvania.
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Wheels Up

Series C in 2017
Wheels Up is a membership-based private aviation company that focuses on reducing the upfront cost to fly privately, providing flexibility, service, and safety. Its mobile app enables members to book flights, manage their accounts, and participate in ride-share opportunities. Its members also have given access to the Wheels Down program. The company was founded in 2013 and headquartered in New York, United States.

Dessa

Series A in 2017
Dessa is an artificial intelligence company that designs, develops, and implements AI systems and tools for enterprises. Founded in 2015 and based in Toronto, Canada, with an additional office in New York, Dessa aims to expand the possibilities of applied machine learning while maintaining a focus on responsible practices. Initially known as Deep Learning, the company rebranded in June 2018 and has since partnered with major organizations across various industries, including banking and telecommunications. Dessa's engineering product, Foundations, addresses significant challenges in machine learning, such as reproducibility and explainability, by creating user-friendly tools that integrate seamlessly into practitioners' workflows. In addition to its core offerings, the company also explores innovative applications of machine learning, showcasing its commitment to advancing technology responsibly. As of early 2020, Dessa operates as a subsidiary of Square, Inc.

Homology Medicines

Series B in 2017
Homology Medicines, Inc., a genetic medicines company, focuses on transforming the lives of patients suffering from rare genetic diseases. Its proprietary platform is designed to utilize its human hematopoietic stem cell derived adeno-associated virus vectors (AAVHSCs) to deliver genetic medicines in vivo either through a gene therapy or nuclease-free gene editing across a range of genetic disorders. The company’s various set of AAVHSCs allows company to target, through a single injection, a range of disease-relevant tissues, including the liver, central nervous system, peripheral nervous system, bone marrow, muscle, and eye. Its lead product candidate is HMI-102, which is in Phase 1/2 pheNIX clinical trial, a gene therapy for the treatment of phenylketonuria (PKU) in adults. The company also develops HMI-103 for the treatment of PKU in pediatric patients; and HMI-202 to treat metachromatic leukodystrophy. Homology Medicines, Inc. was founded in 2015 and is based in Bedford, Massachusetts.

WeWork

Series A in 2017
WeWork, known as The We Company, is a commercial real estate firm that specializes in providing flexible workspaces and office services primarily for entrepreneurs and technology startups. Founded in 2010 and headquartered in New York, the company transforms buildings into dynamic environments that foster creativity, collaboration, and productivity. Its offerings include a variety of workplace solutions such as private offices, shared workspaces, and on-demand access to workstations, catering to diverse member needs. In addition to physical spaces, WeWork provides a range of services through partnerships, enabling members to work, live, and grow. The company also operates WeWork Labs, which supports early-stage startups by providing community and programming to aid their development. With a focus on inclusivity and community, WeWork aims to create an environment where members can thrive and innovate together.

Peloton

Series E in 2017
Peloton is transforming the fitness landscape by integrating high-quality design with advanced technology to offer live and on-demand fitness classes led by top instructors. Founded in 2012 and headquartered in New York, the company operates an interactive fitness platform that includes two main segments: Connected Fitness Products and Subscription services. Revenue from Connected Fitness Products comes from the sale of its bikes and treadmills, along with accessories, delivery, installation, and extended warranties. The Subscription segment, which generates the majority of the company's revenue, includes monthly fees for connected fitness and digital subscriptions. Peloton's unique approach combines hardware, software, and engaging content, creating a socially connected workout experience that appeals to a wide audience. The company sells its products online and through an expanding network of showrooms, primarily serving customers in North America and select international markets.

Spring

Series C in 2017
Spring is a retail company that offers a diverse selection of products, including apparel and home and garden items. It operates as a shopping application designed for iOS devices, allowing users to follow their favorite brands and purchase new arrivals, exclusives, and unique products. Originally founded as Jello Labs, the company rebranded to Spring in July 2014. The founders of Spring are David Tisch, Alan Tisch, and Octavian Costache, and the company is based in New York.

Translate Bio

Series C in 2017
Translate Bio is a clinical-stage biotechnology company based in Lexington, Massachusetts, that focuses on developing messenger RNA (mRNA) therapeutics aimed at treating diseases linked to protein or gene dysfunction. Since its founding in 2011, the company has been working on innovative treatments, including MRT5005, which is currently undergoing Phase I/II clinical trials for cystic fibrosis, and MRT5201, intended for the treatment of ornithine transcarbamylase deficiency. Translate Bio aims to create transformative medicines that address unmet medical needs in rare diseases.

Neon Therapeutics

Series B in 2017
Neon Therapeutics is a clinical-stage biopharmaceutical company. It is focused in the field of neoantigen-targeted therapies, dedicated to transforming the treatment of cancer by directing the immune system towards neoantigens. The company's pipeline products are NEO-PV-01, NEO-PTC-01, and NEO-SV-01.

Rent the Runway

Series E in 2016
Rent the Runway is an e-commerce platform that enables women to rent, subscribe, or purchase designer apparel and accessories. Founded in 2008 and based in New York, the company offers a diverse selection of items including party dresses, gowns, jumpsuits, outerwear, and various accessories such as jewelry and handbags. Rent the Runway has transformed the fashion landscape by promoting the concept of renting over buying, aiming to make fashion more accessible and sustainable. The platform features options for different occasions, including work and special events, and operates through a subscription service, allowing users to access a "closet in the cloud." With partnerships with over 550 designers and a user base exceeding eight million, Rent the Runway employs approximately 1,200 people, with a significant proportion being women and minorities. The company has also established the Rent the Runway Foundation to support female entrepreneurs in their business endeavors.

Castle Creek Biosciences

Venture Round in 2016
Castle Creek Biosciences, Inc. is a gene therapy company based in Exton, Pennsylvania, dedicated to developing and commercializing innovative, personalized gene therapies for rare and serious diseases, particularly those affecting the skin and connective tissue. Founded in 2015, the company aims to address significant unmet medical needs through its specialized pipeline of therapies targeted at these conditions.

AppNexus

Venture Round in 2016
AppNexus Inc. develops a cloud-based software platform that enhances programmatic online advertising for both buyers and sellers of digital inventory. Founded in 2007 and headquartered in New York City, the company offers various tools that optimize campaign performance, including trading solutions and marketplaces for internet advertising. Its platform enables advertisers to create trading desks, advertising networks, and custom exchanges. Additionally, AppNexus provides a digital advertising delivery platform that helps publisher clients maximize revenue from multiple demand sources. Key offerings include the AppNexus Publisher Suite for ad serving and campaign management, as well as PriceCheck, a header bidding solution for various ad formats. The AppNexus Apps program allows third-party technology vendors and existing customers to develop features and expand their reach. AppNexus operates as a subsidiary of Xandr, Inc. and maintains offices in the U.S. and internationally.

Intarcia Therapeutics

Series E in 2016
Intarcia Therapeutics, Inc. is a biopharmaceutical company focused on developing innovative therapies for chronic conditions, particularly type 2 diabetes. The company is advancing its lead product, ITCA 650, through a phase 3 clinical program involving four separate clinical trials, aimed at providing patients with long-term stable dosing of an incretin mimetic therapy. Intarcia also offers the Medici Drug Delivery System, a subcutaneous platform designed to enhance the administration of drug therapies for various chronic diseases, including obesity and autoimmune disorders. Founded in 1997 as BioMedicines, the company rebranded to Intarcia Therapeutics in 2004. It is headquartered in Boston, Massachusetts, with additional facilities in Hayward, California, and a research and development center in Durham, North Carolina.

Oscar Health

Private Equity Round in 2016
Oscar Health is a health insurance company that provides individual and family plans, Medicare Advantage, and small group products. Founded in 2012 and headquartered in New York, Oscar Health operates in several states, including New York, Texas, California, New Jersey, Ohio, and Tennessee. The company aims to enhance the healthcare experience by utilizing technology, design, and data to create user-friendly services. Its platform includes a software application that helps users find doctors based on location and ratings. Oscar Health primarily serves individuals and families who do not receive health insurance from their employers.

Syros Pharmaceuticals

Series C in 2016
Syros Pharmaceuticals is a biopharmaceutical company dedicated to developing treatments for cancer and genetic disorders through innovative gene control medicines. The company is advancing its lead product candidates, including SY-1425, a selective retinoic acid receptor alpha agonist currently undergoing a Phase II clinical trial for specific patient subsets with acute myeloid leukemia and myelodysplastic syndrome, and SY-5609, a cyclin-dependent kinase 7 inhibitor in a Phase I clinical trial for select advanced solid tumors. Syros employs a unique approach that integrates gene regulatory circuit mapping and modulation of gene expression factors, supported by a proprietary platform of assay technologies and bioinformatics. The company collaborates with Incyte Corporation to discover therapeutic targets, particularly for myeloproliferative neoplasms, and has a licensing agreement with TMRC Co. Ltd. for the development of tamibarotene. Founded in 2011 and headquartered in Cambridge, Massachusetts, Syros Pharmaceuticals was previously known as LS22, Inc. and rebranded in 2012.

Scholar Rock

Series B in 2016
Scholar Rock is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializing in the discovery and development of innovative therapies targeting growth factor signaling in serious diseases. The company’s lead product candidate, SRK-015, is a selective inhibitor of myostatin activation and is currently undergoing Phase II clinical trials for spinal muscular atrophy. Additionally, Scholar Rock is advancing SRK-181, which is in Phase I trials for treating cancers resistant to checkpoint inhibitors. The company employs a proprietary platform to design monoclonal antibodies that selectively modulate the activation of growth factors in disease microenvironments, addressing challenges associated with traditional growth factor inhibition. Scholar Rock is also developing a pipeline of candidates for a variety of conditions, including neuromuscular disorders, cancer, fibrosis, and anemia. Furthermore, the company has a collaboration with Gilead Sciences to explore specific inhibitors of transforming growth factor beta for fibrotic diseases. Founded in 2012, Scholar Rock aims to improve patient outcomes through its targeted therapeutic approach.

Allena Pharmaceuticals

Series C in 2015
Allena Pharmaceuticals is developing and commercializing non-systemic protein therapeutics to treat metabolic and orphan diseases, with a particular focus on nephrology and urologic conditions. Its proprietary technological approach enables the design, formulation, and delivery of non-absorbed and stable enzymes orally and in sufficient doses for activity in the GI tract. It was founded in 2011 and headquartered in Newton, Massachusetts.