Protembis GmbH, founded in 2017 and based in Aachen, Germany, specializes in manufacturing surgical equipment designed to enhance patient safety during transcatheter aortic valve replacement (TAVR) procedures. The company's ProtEmbo System addresses a significant complication associated with TAVR—cerebrovascular events—by utilizing an intra-aortic filter device that deflects potential embolic material away from the brain during the valve implantation process. As TAVR technology evolves and is increasingly performed on younger, lower-risk patients, Protembis aims to reduce the risk of adverse neurological outcomes, thereby improving overall patient care and outcomes in the treatment of valvular heart disease.