Mayo Clinic

Vyriad, Inc. is a clinical-stage biotechnology company focused on developing targeted cancer therapies through the use of engineered viruses that selectively target cancer cells while stimulating immune responses to prevent recurrence. The company specializes in oncolytic immunovirotherapy products derived from engineered oncolytic vesicular stomatitis virus and oncolytic measles virus platforms, which aim to destroy cancer cells without damaging normal tissues. In addition to its therapeutic developments, Vyriad is also engaged in creating diagnostic and theranostic tests to accurately predict responses to immunovirotherapy. The company's innovative technologies stem from extensive research conducted by experts at Mayo Clinic and the University of Miami. Established in 2012 and headquartered in Rochester, Minnesota, Vyriad has entered into a strategic partnership with Regeneron Pharmaceuticals to enhance its offerings in the oncology sector.

Collider activates, connects, and empowers early-stage entrepreneurs in Rochester, Minnesota.

Laplace developing Transcatheter Tricuspid Valve Technology to offer an increase in life expectancy and an improvement to the quality of life to worldwide patients with tricuspid regurgitation.

nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.

StemoniX Inc. is a biotechnology company that specializes in stem cell technologies to enhance drug discovery and personalized medicine. Founded in 2014 and headquartered in Minneapolis, Minnesota, with an additional office in La Jolla, California, StemoniX provides innovative platforms for pharmaceutical and research institutions. Its flagship solution focuses on the three-dimensional printing of stem-cell-derived human tissue, enabling the creation of living cells in larger formats. This technology is particularly beneficial for studying various diseases, including heart disease, dementia, breast cancer, autism, and ALS. By advancing the production and application of stem cell technologies, StemoniX aims to meet the evolving needs of the healthcare sector.

Ambient Clinical Analytics is the creator of a software platform designed for data assimilation, communication and analytics. It is based on decision support tools initially deployed in the intensive care unit (ICU) or emergency department of hospitals. Our software consists of algorithms that mine data from electronic medical records (EMR). It then presents that data to the physicians and nurses so they may facilitate real-time clinical decision making and care delivery. These products are positioned as add on applications that are designed to easily integrate with the current major EMR providers.

Geneticure Inc. is a pharmacogenetic testing company focused on developing personalized medicine solutions for patients with hypertension. Founded in 2012 and based in Eden Prairie, Minnesota, the company offers a non-invasive genetic test that analyzes DNA from a cheek swab to identify genetic variants related to the renal, vascular, and cardiac systems. This information helps clinicians determine the most effective treatment options tailored to individual patients based on their unique genetic profiles. Geneticure's testing process includes DNA extraction, genotyping, and the provision of genetic results directly to healthcare providers, accompanied by a decision tree that prioritizes functional genes. This personalized approach aims to optimize blood pressure therapy and improve patient outcomes. Additionally, Geneticure is working on two more pharmacogenomic panels to expand its offerings in personalized medicine.

Torax Medical, Inc. develops and markets products/devices to restore the barrier function of sphincters. The company’s products include LINX, a reflux management system to treat patients diagnosed with gastroesophageal reflux disease; and FENIX, a continence restoration system for the treatment of fecal incontinence. It sells its products in Europe and the United States. Torax Medical, Inc. was founded in 2002 and is based in Shoreview, Minnesota. As of March 23, 2017, Torax Medical, Inc. operates as a subsidiary of Ethicon, Inc.

Ambient Clinical Analytics is the creator of a software platform designed for data assimilation, communication and analytics. It is based on decision support tools initially deployed in the intensive care unit (ICU) or emergency department of hospitals. Our software consists of algorithms that mine data from electronic medical records (EMR). It then presents that data to the physicians and nurses so they may facilitate real-time clinical decision making and care delivery. These products are positioned as add on applications that are designed to easily integrate with the current major EMR providers.

Torax Medical, Inc. develops and markets products/devices to restore the barrier function of sphincters. The company’s products include LINX, a reflux management system to treat patients diagnosed with gastroesophageal reflux disease; and FENIX, a continence restoration system for the treatment of fecal incontinence. It sells its products in Europe and the United States. Torax Medical, Inc. was founded in 2002 and is based in Shoreview, Minnesota. As of March 23, 2017, Torax Medical, Inc. operates as a subsidiary of Ethicon, Inc.

Torax Medical, Inc. develops and markets products/devices to restore the barrier function of sphincters. The company’s products include LINX, a reflux management system to treat patients diagnosed with gastroesophageal reflux disease; and FENIX, a continence restoration system for the treatment of fecal incontinence. It sells its products in Europe and the United States. Torax Medical, Inc. was founded in 2002 and is based in Shoreview, Minnesota. As of March 23, 2017, Torax Medical, Inc. operates as a subsidiary of Ethicon, Inc.

Kardia Health Systems is a healthcare information technology firm offering the delivery of specialty medicine, starting with cardiology. Using Internet technology and a Software-as-a-Service (SaaS) business model, Kardia makes this technology accessible to practices of varying sizes. Kardia Health Systems, Inc. was incorporated in 2006 and is based in Golden Valley, Minnesota.

Kardia Health Systems is a healthcare information technology firm offering the delivery of specialty medicine, starting with cardiology. Using Internet technology and a Software-as-a-Service (SaaS) business model, Kardia makes this technology accessible to practices of varying sizes. Kardia Health Systems, Inc. was incorporated in 2006 and is based in Golden Valley, Minnesota.

Torax Medical, Inc. develops and markets products/devices to restore the barrier function of sphincters. The company’s products include LINX, a reflux management system to treat patients diagnosed with gastroesophageal reflux disease; and FENIX, a continence restoration system for the treatment of fecal incontinence. It sells its products in Europe and the United States. Torax Medical, Inc. was founded in 2002 and is based in Shoreview, Minnesota. As of March 23, 2017, Torax Medical, Inc. operates as a subsidiary of Ethicon, Inc.