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Comanche Biopharma is a biopharmaceutical company that develops siRNA therapy for the treatment of preeclampsia.

Cerevance is a developer of novel therapeutics intended to advance new medicines for serious neurological diseases.The company's therapeutics applies it's technology called NETSseq to reveal transcriptional and epigenetic differences between specific cell types in mature human brains, enabling healthcare providers to detect and tackle the early onset of various neurological diseases.

Pretzel was founded by some of the world’s foremost academics in mitochondrial biology, and we benefit from the leadership of accomplished experts in drug discovery, drug development, and company formation. Our name is inspired by the focal point of our science, the mitochondrion, whose highly folded inner membrane is one of many fascinating features that make it unlike any other organelle in the body.

Fractyl Health Inc. is a medical device company specializing in innovative therapies for metabolic diseases, particularly type 2 diabetes and obesity. The company's flagship product, Revita DMR, is a minimally invasive procedure that utilizes hydrothermal ablation to rejuvenate the lining of the duodenum, effectively addressing the underlying causes of these conditions. By focusing on transforming the treatment of metabolic diseases from merely managing symptoms to providing durable, disease-modifying solutions, Fractyl Health aims to significantly improve patient health outcomes. Founded in 2010 and based in Lexington, Massachusetts, the company is committed to developing curative therapies that lessen the burden on patients, healthcare providers, and payers.

Merlin Labs is building an autonomous infrastructure for the sky above us, enabling goods, and eventually people, to fly without pilots.

Areteia Therapeutics is a biotechnology company committed to putting asthma patients in better control of their disease. The company was spun out of Pennsylvania-based Knopp, which published results from its phase 2 clinical trial last year that showed its oral drug candidate could reduce the count of blood eosinophil, which is an indication of improving lung function and is found in several asthma-related treatments.

FYTO provides innovative solutions which improve the economic and environmental sustainability of agriculture for farmers around the world. FYTO is developing: NOVEL NUTRIENT-DENSE CROPS that have ultra-high yields and ultra-low resource requirements, STATE-OF-THE ART CULTIVATION AND HARVESTING SYSTEMS for exceptional quality and consistency, CLIMATE-FRIENDLY METHODOLOGIES for resiliency and long-term sustainability, and a range of GROUNDBREAKING AGRICULTURAL PRODUCTS such as animal feed and biofertilizer.

Courier provides an API designed for developers to enhance user notification delivery by intelligently routing messages across various existing channels, such as email and messaging platforms. The API takes into account factors like user online status and previous engagement levels to determine the most effective communication method. Over the years, Courier has evolved significantly, continuously adapting to technological advancements to better serve its customers while maintaining stability in its management and operational approach. The company emphasizes the importance of customer success, fostering long-term relationships with its largest clients and collaborating closely to prepare for future developments in the industry.

Sesame, Inc., operating as SesameCare, is a New York-based company that provides a platform for booking medical appointments and consultations. Founded in 2018, the company aims to simplify healthcare by connecting patients directly with doctors, offering transparent pricing and clear descriptions of medical services. SesameCare primarily serves uninsured individuals or those who prefer to pay for their healthcare services upfront. By addressing the complexities and hidden costs often associated with traditional healthcare, Sesame seeks to make quality medical care more accessible and affordable for a broader range of patients.

Nava is a New York-based company that specializes in health insurance brokerage services aimed at delivering high-quality, affordable healthcare solutions to employers and their employees. The firm provides a range of healthcare tools, year-round employee advocacy, and continuous measurement to assess and recommend healthcare plans. By focusing on these aspects, Nava helps clients manage their employee benefits effectively while reducing overall plan costs. This approach allows businesses to offer the necessary benefits to their workforce, ensuring both accessibility and affordability in healthcare coverage.

Strella Biotechnology, Inc. designs and manufactures sensors based device that maximizes the freshness of fresh produce throughout the supply chain. The company provides an ethylene-detection device that determines ripeness by calculating the ethylene gas produced by fruit and maximizes freshness and reduces spoilage of fruit. Strella Biotechnology, Inc. was founded in 2018 and is based in Philadelphia, Pennsylvania.

Invetx, Inc. is a biotechnology company based in Boston, Massachusetts, that specializes in developing protein-based therapeutics for animal health care. The company focuses on creating biopharmaceutical solutions that apply human biotechnology advancements to veterinary medicine. Invetx aims to build a premier innovation platform for veterinary therapeutics, collaborating with leading biotechnology firms, investors, and industry experts. Its team, which includes veterinary scientists and clinicians, is dedicated to discovering and developing a diverse portfolio of therapies and technologies. The company's vision is to enhance health outcomes for both pets and farm animals by leveraging biopharma technologies in the global animal health industry.

Celsius Therapeutics, Inc. is a biotechnology company based in Cambridge, Massachusetts, that focuses on the development and research of innovative drugs. Established in 2017, the company utilizes single-cell genomic analysis and machine learning to gain insights into the cellular ecosystems of diseases. This approach allows Celsius Therapeutics to identify critical biomarkers that can enhance patient care and contribute to the creation of transformative medicines. The company's commitment to advancing the understanding of complex diseases positions it as a key player in the biotechnology sector.

LifeMine Therapeutics, Inc., a biotechnology company, engages in the genomic discovery of new drug modalities from eukaryotic microbes. It utilizes an integrated genomically-enabled drug discovery platform to discover and develop a pipeline of new drugs from fungi. The company was incorporated in 2016 and is based in Cambridge, Massachusetts with an additional office in New York, New York.

Agolo summarizes information faster and with broader coverage than any human. It also uses artificial intelligence to create summaries from your information in real-time. The company helps analysts act strategically instead of processing information. Agolo’s technology replicates the ingenuity of the human mind by analyzing content through the identification of various subjects and drawing connections between them. The company’s AI platform can analyze thousands of documents and produce a summary of the five key points, specific to the reader’s interests, in real-time. Agolo was founded in 2012 and is headquartered in New York, NY, USA.

Fishtown Analytics Inc. develops and operates a software-as-a-service (SaaS) based open-source data engineering platform. The company offers data build tool (dbt), which enables data analysts and engineers to organize, cleanse, denormalize, filter, rename, and pre-aggregate data for analysis. It offers data modeling, data warehousing, KPI measurement, event tracking, data science, and training services and data analytics consulting services. Fishtown Analytics Inc. was founded in 2016 and is based in Philadelphia, Pennsylvania.

RightHand Robotics, Inc. specializes in manufacturing robotic order-picking systems designed for various industrial applications, including e-commerce, food handling, and flexible manufacturing. The company offers innovative products such as the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that enhances the robots' ability to grasp items gently and make adjustments to avoid errors. Their technology allows robots to automatically grasp a wide range of items from bins and cases, eliminating the need for extensive data-entry or parameter-tuning, thereby making the systems cost-effective and adaptable to the evolving needs of businesses. Founded in 2015, RightHand Robotics is headquartered in Cambridge, Massachusetts, with a sales and business development office located in Frankfurt, Germany.

Ventus Therapeutics U.S., Inc. is a biopharmaceutical company based in Natick, Massachusetts, with an additional location in Montreal, Canada. Founded in 2019, it focuses on discovering and developing novel small-molecule medicines that target the innate immune system to address autoimmune diseases, inflammatory diseases, and cancer. The company employs a structural immunology platform that integrates protein engineering to elucidate molecular structures and mechanisms of action. This platform facilitates the development of precise binding and functional screening assays, as well as structure-based modeling. Ventus Therapeutics is advancing an emerging pipeline of drug programs aimed at key targets within the innate immune system, leveraging its proprietary capabilities in rational and structure-based drug design.

Seismic Therapeutic is a biotechnology company focused on accelerating immunology drug development through the integration of machine learning in the biologics discovery process. Utilizing its IMPACT™ platform, Seismic Therapeutic aims to tackle key challenges in biologics discovery by combining structural biology, protein engineering, and translational immunology. This comprehensive approach facilitates the creation of optimized therapies that can reach patients more quickly. The company is developing a pipeline of innovative biologics targeting adaptive immune system dysregulation, with the goal of treating autoimmune diseases.

Scandit AG, established in 2009 and headquartered in Zurich, Switzerland, specializes in mobile computer vision and augmented reality solutions, focusing on barcode scanning software. Its offerings include the Scandit Keyboard Wedge, which enables enterprise-grade barcode scanning on mobile devices, and the Barcode Scanner SDK, which allows for barcode scanning integration in web applications. The MatrixScan technology enhances the speed of barcode and text recognition, making it valuable for industries such as retail, logistics, manufacturing, healthcare, and government. Scandit's solutions are designed to improve operational efficiency by enabling mobile shopping, self-checkout, inventory management, and asset tracking, while also facilitating patient and medication tracking in healthcare settings. The company serves a diverse clientele, including well-known organizations like 7-Eleven, Carrefour, and Toyota, among others, and has additional offices in San Francisco, Boston, London, and Warsaw.

Cockroach Labs, Inc. specializes in the development of open-source database software, notably CockroachDB, a cloud-native, distributed SQL database designed for modern application development. Founded in 2015 and headquartered in New York, with an additional office in Cambridge, Massachusetts, the company provides a robust solution that combines the functionality of SQL with the horizontal scalability typical of NoSQL systems. CockroachDB is engineered to support strongly-consistent ACID transactions and offers an SQL API for data management. Its architecture ensures minimal latency disruption and resilience against failures across various levels, including disk, machine, rack, and datacenter. Serving a diverse clientele from startups to Fortune 500 companies, Cockroach Labs enables organizations across multiple industries, including banking, retail, and media, to build applications that can scale efficiently and maintain operational continuity.

Wonder is a gaming company focused on developing an all-in-one gaming platform specifically for Android mobile devices. The platform enables users to play, stream, and share games seamlessly across different devices, thereby enhancing the overall gaming experience. Additionally, Wonder is exploring VR-ready gaming hardware to further enrich its offerings. Currently, the company operates in stealth mode, indicating that it is in the early stages of development and not yet publicly available.

Universe is a mobile-based website builder established in 2014 and headquartered in Brooklyn, New York. The platform aims to empower users to create customized websites quickly and easily, catering to the needs of small business owners and individuals who prefer mobile solutions. By offering a unique approach that eliminates complicated templates, Universe utilizes customizable website filters that allow users to arrange photos, videos, and icons on a grid pattern through a simple drag-and-drop interface. This enables users to build mobile-optimized websites in just minutes using the company's iOS app, providing them with full control over their online presence.

Quartet Health, Inc. develops and operates a cloud based platform that allows communication and collaboration between medical providers with behavioral health providers for patient care. Its platform works with health plans and health systems to provide actionable population insights and reports on behavioral health conditions to improve patient outcomes, as well as provides tools for patient self-management. The company was founded in 2014 and is based in New York, New York.

Mabl Inc. offers an automated testing service that leverages machine learning to identify regressions and automatically fix broken tests. Founded in 2016 and based in Boston, Massachusetts, the company provides a scriptless testing solution as part of its software-as-a-service (SaaS) offerings. Mabl facilitates machine-driven regression testing and integrates seamlessly into the continuous integration and continuous delivery (CI/CD) development lifecycle. Its platform allows software development teams to create, execute, and maintain auto-healing tests efficiently, ensuring the rapid delivery of high-quality applications. Mabl serves a range of enterprise clients, including Johnson Controls, Liberty Mutual, Molina Healthcare, JetBlue, Dollar Shave Club, and Charles Schwab, who rely on its services for testing their critical applications.

We believe everyone should have the opportunity to live their best lives and age with dignity. That’s why we’re reinventing primary care with an approach designed to profoundly improve the healthcare and aging experience for older adults and their loved ones.

Modern Age is a health and wellness platform focused on improving the aging process for individuals. It offers health monitoring software that employs computer vision and machine learning to assess skin, hair, and bone health. The platform also integrates data collected from smart bands to create a comprehensive digital record of an individual's well-being. By analyzing this information, Modern Age provides personalized insights and treatment recommendations, empowering users to manage their health more effectively and lead healthier lives as they age.

RightHand Robotics, Inc. specializes in manufacturing robotic order-picking systems designed for various industrial applications, including e-commerce, food handling, and flexible manufacturing. The company offers innovative products such as the ReFlex SF, which features a 3D-printed palm equipped with servos and compliant fingers, and the ReFlex TakkTile, a tactile sensor that enhances the robots' ability to grasp items gently and make adjustments to avoid errors. Their technology allows robots to automatically grasp a wide range of items from bins and cases, eliminating the need for extensive data-entry or parameter-tuning, thereby making the systems cost-effective and adaptable to the evolving needs of businesses. Founded in 2015, RightHand Robotics is headquartered in Cambridge, Massachusetts, with a sales and business development office located in Frankfurt, Germany.

Altana AI specializes in developing artificial intelligence software solutions focused on enhancing global trade. Founded in 2018 and based in New York, the company leverages comprehensive global economic data to provide visibility across borders and improve risk management for governments, enterprises, and financial institutions. Altana's offerings include AI-based data fusion and decision support tools, centered around the Altana Trade Knowledge Graph. This innovative platform delivers a real-time overview of transactions, ownership, movements, cyber activity, and associated risks within the global trade network. By facilitating better data-driven insights, Altana aims to make trade safer, more efficient, and more profitable for its clients, including regulators, businesses, financial service providers, and logistics companies.

ROME Therapeutics, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative therapies for cancer and autoimmune diseases. Established in 2019, ROME Therapeutics is pioneering the exploration of the repeatome, which consists of extensive regions of genetic material previously considered "junk DNA." The company has identified several drug targets and is actively advancing multiple discovery programs. To facilitate its research, ROME has assembled a team of experts across various disciplines, including oncology, immunology, virology, and machine learning, to harness this uncharted area of biology for therapeutic advancements.

Nym Health Inc. specializes in developing advanced medical coding technology aimed at enhancing revenue cycle processes within healthcare facilities. Its flagship product, Nym, offers a direct-to-billing autonomous coding solution that significantly reduces claims denials and operational costs while accelerating payment cycles and ensuring audit-readiness. The platform automatically identifies and captures relevant clinical information from patient charts, assigning codes only to fully understood cases; unhandled charts are sent back for human coding. Additionally, Nym provides a detailed audit-trail view that explains the rationale behind each coding decision, facilitating quick comprehension for validation, compliance, and appeals purposes. Founded in 2017 and headquartered in Boston, Massachusetts, the company also maintains a research and development center in Tel Aviv-Yafo, Israel.

Norby is an audience relationship toolkit built for creators and brands.

TMRW Life Sciences is a developer of a cryo-storage platform intended to improve the success rates of assisted reproductive technology. The company's platform offers an in-clinic robotic storage system and a fully digital chain of custody from clinic to offsite longterm storage, continuous remote and local monitoring and electronically integrated processes characterized by digital health signals received from every oocyte and embryo daily, enabling clients to streamline embryology lab operations, eliminate manual steps and integrates digital quality control.

Kindbody operates a health and tech company intended to offer fertility services and treatments for the modern woman. It offers a full range of services including intrauterine insemination, in-vitro fertilization, donor support, egg freezing, and embryo freezing, enabling women to improve their overall health and wellbeing.

Ribon Therapeutics, Inc. is a biotechnology company based in Lexington, Massachusetts, founded in 2015. The company is focused on developing innovative cancer therapies that target monoPARP proteins, which are essential regulators of cancer cell survival. Ribon's scientific founders have made significant contributions to the understanding of PARPs, or poly(ADP-ribose) polymerases, and their roles in cancer. Leveraging this expertise, Ribon is establishing a proprietary drug discovery platform aimed at exploring the molecular actions and biological functions of monoPARPs. This platform supports the creation of a pipeline of therapeutics that selectively target these proteins to potentially treat cancer and other diseases. Ribon Therapeutics is supported by notable life science investors, enhancing its capability to advance its research and development efforts.

Merlin Labs is building an autonomous infrastructure for the sky above us, enabling goods, and eventually people, to fly without pilots.

Bowery Farming Inc., a farming company, provides post-organic produce. The company offers baby kale, blend, lettuce, arugula, kale mix, and basil products. It sells its products through grocery stores and restaurants. The company was founded in 2014 and is based in New York, New York.

Overture Life, Inc. develops robots for in vitro fertilization applications. The company was incorporated in 2017 and is based in New York, New York.

Dyno Therapeutics Inc. specializes in the development of adeno-associated virus (AAV) vectors for in vivo delivery of gene therapies. Founded in 2018 and based in Cambridge, Massachusetts, the company utilizes an artificial intelligence-driven approach that integrates DNA synthesis, sequencing, and machine learning. This innovative methodology enables the design of novel gene vectors with an emphasis on cell-targeting capsid proteins derived from AAV, which is recognized as the most commonly used vector in gene therapy applications. By leveraging quantitative high-throughput in vivo experimentation, Dyno Therapeutics aims to enhance the effectiveness and precision of gene therapy solutions.

Headway is a mental healthcare system provider based in New York, established in 2019 by founders Andrew Adams, Jake Sussman, Dan Ross, and Kevin Chan. The company focuses on improving access to mental health services by developing a health insurance advisory platform that connects patients with therapists who traditionally do not accept insurance. In addition to facilitating these connections, Headway offers administrative support to therapists, enhancing their ability to provide care while navigating the complexities of insurance processes. Through this approach, Headway aims to make mental healthcare more accessible and efficient for both patients and providers.

Affinia Therapeutics Inc. is a biotechnology company focused on developing gene therapies for various diseases, particularly those affecting muscle and the central nervous system (CNS). Founded in 2019 and based in Waltham, Massachusetts, the company specializes in creating rationally designed adeno-associated virus (AAV) vectors. By integrating synthetic and systems biology with high-throughput screening and advanced resolution techniques, Affinia Therapeutics aims to address significant unmet medical needs. The company’s innovative approach allows for the development of novel gene therapies with enhanced properties, targeting the treatment of devastating diseases and improving the lives of affected individuals.

Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions. The company was founded in 2021 and is headquartered in Stamford, CT.

Outlier.org Inc. develops an online educational platform. It offers Outlier.org, a platform that provides online courses on calculus and psychology. The company’s platform also provides video content, online textbooks, one-on-one tutoring, artificial intelligence-proctored assessments, problem sets, and active learning techniques. Outlier.org Inc. was formerly known as Outlier School Inc. The company was incorporated in 2018 and is based in Brooklyn, New York.

Invivyd is a biotechnology company focused on developing advanced antibodies to neutralize SARS-CoV-2, SARS-CoV-1, and other potentially emerging coronaviruses. Founded in 2020 and headquartered in Waltham, Massachusetts, the company aims to create best-in-class therapeutic and prophylactic treatments that surpass the efficacy of existing antibody programs. Its innovative portfolio features multiple non-competing antibodies, each targeting distinct viral epitopes, which is designed to minimize the risk of viral escape. By leveraging cutting-edge antibody discovery technologies, Invivyd seeks to enhance the potency and durability of its antibody candidates, addressing a critical need in the ongoing fight against coronaviruses.

Tend provides hassle-free, personalized, and straightforward dental services with a focus on patient happiness. Tend studios offer a full range of dental services, from checkups to implants and veneers. Tend prioritizes safety with health checks, contactless check-in, enhanced PPE, and more.

Ventus Therapeutics U.S., Inc. is a biopharmaceutical company based in Natick, Massachusetts, with an additional location in Montreal, Canada. Founded in 2019, it focuses on discovering and developing novel small-molecule medicines that target the innate immune system to address autoimmune diseases, inflammatory diseases, and cancer. The company employs a structural immunology platform that integrates protein engineering to elucidate molecular structures and mechanisms of action. This platform facilitates the development of precise binding and functional screening assays, as well as structure-based modeling. Ventus Therapeutics is advancing an emerging pipeline of drug programs aimed at key targets within the innate immune system, leveraging its proprietary capabilities in rational and structure-based drug design.

Lightmatter, Inc. is an artificial intelligence (AI) hardware company based in Boston, Massachusetts, that specializes in integrated optical technology to develop advanced computing processors. Founded in 2017, the company has created a silicon chip that utilizes light signals for processing, offering a new approach to AI computation. This technology accelerates critical operations in deep neural networks by employing programmable photonic elements alongside traditional transistors, enhancing the speed and efficiency of data processing while minimizing power consumption. Lightmatter's innovations aim to improve various AI applications, including image recognition and natural language processing, contributing to the advancement of next-generation AI-powered computing solutions.

SecurityScorecard, Inc. is a cybersecurity ratings and continuous monitoring platform that evaluates the cybersecurity strength of businesses and third-party vendors. Founded in 2013, the company has developed a patented technology that provides instant risk ratings for over a million companies, helping organizations manage their cybersecurity risks more effectively. Its offerings include ThreatMarket, a cloud-based vulnerability search engine that assesses security posture across various risk categories, and Score Planner, which allows companies to explore remediation strategies. Additionally, SecurityScorecard provides tools for vendor risk management, board reporting, and cyber insurance underwriting through its Scorecard Event Log and Atlas platform for questionnaire management. The company serves a global clientele, including Fortune 1000 organizations, and collaborates with value-added resellers and service partners to deliver its solutions. Based in New York, SecurityScorecard aims to enhance organizational resilience by facilitating the identification and mitigation of cybersecurity risks.

Nanit team is a tight-knit collection of scientists, parents and designers—experts in the first beautiful months of human life. They have developed advanced computer vision and machine learning algorithms to help us measure human behavior. They use this knowledge and technology to create innovative products that are safer and smarter, for parents and babies everywhere. Their team comes from great companies like Applied Materials, Diapers.com, Philips, Time Warner and Tiny Love, where they've focused on building brands and products people love.

Dandelion Energy offers affordable geothermal heating and cooling installations. Dandelion Energy's home geothermal system replaces your home’s existing air conditioning and heating equipment with a powerful heat pump and safe, underground pipes that move heat between the earth and home. Kathleen Hannun and Rajeez Quazi founded it in 2017, with its headquarters in Palo Alto in California.

Hyperfine Research Inc. specializes in developing portable magnetic resonance imaging (MRI) scanners, aimed at making medical imaging more accessible. Founded in 2014 and based in Guilford, Connecticut, the company focuses on general anatomical brain imaging and addresses various medical conditions, including headaches, strokes, non-specific muscle weakness, encephalopathy, spinal cord compressions, diabetic foot disease, and musculoskeletal trauma. Within a year of its establishment, Hyperfine successfully produced its first images, and it has since improved the quality and functionality of its imaging technology. The company’s mission is to democratize healthcare by ensuring that medical imaging is available to people worldwide.

Hyperfine Research Inc. specializes in developing portable magnetic resonance imaging (MRI) scanners, aimed at making medical imaging more accessible. Founded in 2014 and based in Guilford, Connecticut, the company focuses on general anatomical brain imaging and addresses various medical conditions, including headaches, strokes, non-specific muscle weakness, encephalopathy, spinal cord compressions, diabetic foot disease, and musculoskeletal trauma. Within a year of its establishment, Hyperfine successfully produced its first images, and it has since improved the quality and functionality of its imaging technology. The company’s mission is to democratize healthcare by ensuring that medical imaging is available to people worldwide.

TScan Therapeutics is a biopharmaceutical company dedicated to developing innovative T cell therapies to treat various cancers, including liquid tumors and solid tumors. The company focuses on engineering T cell receptor (TCR) therapies, with specific candidates aimed at addressing hematologic malignancies and preventing relapse after hematopoietic stem cell transplantation. TScan utilizes a specialized platform that identifies shared T cell antigens and minimizes off-target effects, enhancing the safety and effectiveness of its treatments. The company’s pipeline includes both liquid tumor therapies and multiplexed TCR-T candidates for solid tumors. Founded in 2018, TScan Therapeutics is headquartered in Waltham, Massachusetts, and comprises a team of experts committed to expanding treatment options for patients with limited therapeutic alternatives.

Verve Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to reduce the risk of coronary artery disease, a leading cause of death globally. Founded in 2018 and headquartered in Cambridge, Massachusetts, with a research facility in Philadelphia, the company leverages human genetic analysis and gene-editing technologies to create treatments that offer lifelong protection from this condition. Verve has established strategic alliances, including collaborations with Beam Therapeutics to advance delivery technologies targeting cardiovascular issues and with Verily for developing gene editing delivery vehicles. Formerly known as Endcadia, Verve Therapeutics rebranded in September 2019 to reflect its commitment to addressing heart disease through advanced genetic solutions.

Cockroach Labs, Inc. specializes in the development of open-source database software, notably CockroachDB, a cloud-native, distributed SQL database designed for modern application development. Founded in 2015 and headquartered in New York, with an additional office in Cambridge, Massachusetts, the company provides a robust solution that combines the functionality of SQL with the horizontal scalability typical of NoSQL systems. CockroachDB is engineered to support strongly-consistent ACID transactions and offers an SQL API for data management. Its architecture ensures minimal latency disruption and resilience against failures across various levels, including disk, machine, rack, and datacenter. Serving a diverse clientele from startups to Fortune 500 companies, Cockroach Labs enables organizations across multiple industries, including banking, retail, and media, to build applications that can scale efficiently and maintain operational continuity.

EQRx operates as a biotechnology company, focused on re-engineering the process from drug discovery to patient delivery with the goal of offering a market-based solution for the rising cost of medicines. By bringing together stakeholders from across the healthcare system and utilizing the latest advances in science and technology, the company seeks to discover, develop and deliver high-quality, patent-protected medicines more efficiently and cost-effectively than ever before. The company was founded in 2019 and is based in Cambridge, Massachusetts, United States.

LifeMine Therapeutics, Inc., a biotechnology company, engages in the genomic discovery of new drug modalities from eukaryotic microbes. It utilizes an integrated genomically-enabled drug discovery platform to discover and develop a pipeline of new drugs from fungi. The company was incorporated in 2016 and is based in Cambridge, Massachusetts with an additional office in New York, New York.

FogPharma is a healthcare company founded in 2015 and headquartered in Gloucester, Massachusetts. The firm is dedicated to the pharmaceutical sector, with a primary focus on developing innovative treatments for cancer. It operates with the support of a diverse group of private and institutional investors, fostering collaboration among its founders, employees, and advisors. FogPharma aims to create a new class of medicines designed to extend and enhance the lives of cancer patients. The company's commitment to its mission drives its efforts to pioneer effective solutions in cancer treatment.

Warp is a developer of a Rust-based coding terminal aimed at enhancing productivity in coding and application development. Its software innovatively transforms the traditional command-line interface by dividing the terminal output into a sequence of commands, rather than presenting it as a single buffer. This approach replaces the standard character buffer with a comprehensive text editor, allowing software developers to efficiently navigate, copy, save, and share their work. Warp's terminal redefines the user experience by evolving from a single-user utility into a collaborative platform, where sessions, blocks, and environments are persistent, searchable, and easily shared via links.

Established in 2008, HODINKEE is the destination for all things in the world of horology. Over the past decade, ​founder Ben Clymer and team have​ grown HODINKEE into a robust media and retail platform by providing its respected point of view on industry news and releases, investing in engaging and creative storytelling, producing a designated podcast, printing a bi-annual publication, and launching and growing its own retail outlet, HODINKEE Shop. At its core, HODINKEE’s goal is to bring its readers and consumers the best in luxury products in a way that is approachable, authentic, and honest.

Headway is a mental healthcare system provider based in New York, established in 2019 by founders Andrew Adams, Jake Sussman, Dan Ross, and Kevin Chan. The company focuses on improving access to mental health services by developing a health insurance advisory platform that connects patients with therapists who traditionally do not accept insurance. In addition to facilitating these connections, Headway offers administrative support to therapists, enhancing their ability to provide care while navigating the complexities of insurance processes. Through this approach, Headway aims to make mental healthcare more accessible and efficient for both patients and providers.

Invivyd is a biotechnology company focused on developing advanced antibodies to neutralize SARS-CoV-2, SARS-CoV-1, and other potentially emerging coronaviruses. Founded in 2020 and headquartered in Waltham, Massachusetts, the company aims to create best-in-class therapeutic and prophylactic treatments that surpass the efficacy of existing antibody programs. Its innovative portfolio features multiple non-competing antibodies, each targeting distinct viral epitopes, which is designed to minimize the risk of viral escape. By leveraging cutting-edge antibody discovery technologies, Invivyd seeks to enhance the potency and durability of its antibody candidates, addressing a critical need in the ongoing fight against coronaviruses.

Decibel Therapeutics is a clinical-stage biotechnology company dedicated to discovering and developing therapies aimed at protecting, repairing, and restoring hearing. The company focuses on a range of hearing disorders, including those related to cancer treatments, cystic fibrosis, noise exposure, age-related and genetic hearing loss, as well as tinnitus. It utilizes advanced techniques such as single-cell genomics, bioinformatics, and precision gene therapy technologies to enhance its understanding of inner ear pathology and to develop effective treatments. Decibel Therapeutics also offers expertise in drug delivery to the inner ear, imaging, and pharmacokinetic modeling, contributing to innovative therapeutic approaches for patients experiencing various forms of hearing loss. Founded in 2013 and based in Boston, Massachusetts, Decibel Therapeutics was previously known as Hearing, Inc. before rebranding in 2014.

Superplastic, Inc. is a character-based product and entertainment company founded in 2017 and based in Burlington, Vermont. The company specializes in manufacturing and marketing limited edition art toys, apparel, games, and animation, featuring unique characters created in collaboration with renowned artists. Superplastic leverages the principles of effort and scarcity to enhance the value of its offerings, creating exclusive works of art for a select audience. The company also operates a platform that engages customers through various media, including animated videos and music, enabling interactions with its synthetic superstars in innovative ways. Products are primarily sold online, reflecting a modern approach to retail and entertainment.

Nym Health Inc. specializes in developing advanced medical coding technology aimed at enhancing revenue cycle processes within healthcare facilities. Its flagship product, Nym, offers a direct-to-billing autonomous coding solution that significantly reduces claims denials and operational costs while accelerating payment cycles and ensuring audit-readiness. The platform automatically identifies and captures relevant clinical information from patient charts, assigning codes only to fully understood cases; unhandled charts are sent back for human coding. Additionally, Nym provides a detailed audit-trail view that explains the rationale behind each coding decision, facilitating quick comprehension for validation, compliance, and appeals purposes. Founded in 2017 and headquartered in Boston, Massachusetts, the company also maintains a research and development center in Tel Aviv-Yafo, Israel.

Tend provides hassle-free, personalized, and straightforward dental services with a focus on patient happiness. Tend studios offer a full range of dental services, from checkups to implants and veneers. Tend prioritizes safety with health checks, contactless check-in, enhanced PPE, and more.

Our first app, HAGS: Yearbook Signatures, let let tens of thousands of students sign their yearbooks through Snapchat. HAGS will be relaunching as an entirely new space for high school students to interact with their class. Based in New York.

HAGS is a platform for high school students built on top of Snapchat. The company works with over 200+ high school ambassadors across the U.S. as they continue to deliver products and experiences created by and for Gen-Z. HAGS will launch its new digital classrooms in beta in six high schools in California, and students at these schools will be able to walk into their high school on HAGS and interact with their classmates.

Fractyl Health Inc. is a medical device company specializing in innovative therapies for metabolic diseases, particularly type 2 diabetes and obesity. The company's flagship product, Revita DMR, is a minimally invasive procedure that utilizes hydrothermal ablation to rejuvenate the lining of the duodenum, effectively addressing the underlying causes of these conditions. By focusing on transforming the treatment of metabolic diseases from merely managing symptoms to providing durable, disease-modifying solutions, Fractyl Health aims to significantly improve patient health outcomes. Founded in 2010 and based in Lexington, Massachusetts, the company is committed to developing curative therapies that lessen the burden on patients, healthcare providers, and payers.

Invivyd is a biotechnology company focused on developing advanced antibodies to neutralize SARS-CoV-2, SARS-CoV-1, and other potentially emerging coronaviruses. Founded in 2020 and headquartered in Waltham, Massachusetts, the company aims to create best-in-class therapeutic and prophylactic treatments that surpass the efficacy of existing antibody programs. Its innovative portfolio features multiple non-competing antibodies, each targeting distinct viral epitopes, which is designed to minimize the risk of viral escape. By leveraging cutting-edge antibody discovery technologies, Invivyd seeks to enhance the potency and durability of its antibody candidates, addressing a critical need in the ongoing fight against coronaviruses.

Kindbody operates a health and tech company intended to offer fertility services and treatments for the modern woman. It offers a full range of services including intrauterine insemination, in-vitro fertilization, donor support, egg freezing, and embryo freezing, enabling women to improve their overall health and wellbeing.

UJET, Inc. is a customer support software company that specializes in developing cloud-based contact center solutions. Founded in 2015 and headquartered in San Francisco, California, with additional offices in New York and Seoul, UJET focuses on enhancing customer communications through advanced voice and chat solutions. The platform integrates seamlessly with popular customer relationship management systems like Salesforce, Zendesk, and Kustomer, enabling support agents to efficiently manage client requests across various channels, including voice, chat, and mobile. UJET's technology provides features such as real-time wait time messaging and context-aware assistance, which enhance the overall customer experience and improve agent performance. The company prioritizes security and compliance, ensuring that its offerings meet SOC2 Type II and HIPAA standards.

Verve Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to reduce the risk of coronary artery disease, a leading cause of death globally. Founded in 2018 and headquartered in Cambridge, Massachusetts, with a research facility in Philadelphia, the company leverages human genetic analysis and gene-editing technologies to create treatments that offer lifelong protection from this condition. Verve has established strategic alliances, including collaborations with Beam Therapeutics to advance delivery technologies targeting cardiovascular issues and with Verily for developing gene editing delivery vehicles. Formerly known as Endcadia, Verve Therapeutics rebranded in September 2019 to reflect its commitment to addressing heart disease through advanced genetic solutions.

PatientPing, Inc. operates a national care coordination network designed to connect healthcare providers through real-time notifications when patients receive care. Founded in 2013 and headquartered in Boston, Massachusetts, the company offers technology solutions for various healthcare stakeholders, including Accountable Care Organizations, hospitals, payers, and post-acute care facilities. Its network comprises a range of healthcare professionals, such as emergency case managers, primary care physicians, and care coordinators, facilitating improved collaboration and information sharing. PatientPing also features a tool called Spotlights, which analyzes real-time data to identify trends in healthcare utilization and performance. The company has formed a strategic partnership with MedAllies, Inc. and operates as a subsidiary of SVB Leerink Holdings LLC, focusing on enhancing patient outcomes and experiences through coordinated care.

Scandit AG, established in 2009 and headquartered in Zurich, Switzerland, specializes in mobile computer vision and augmented reality solutions, focusing on barcode scanning software. Its offerings include the Scandit Keyboard Wedge, which enables enterprise-grade barcode scanning on mobile devices, and the Barcode Scanner SDK, which allows for barcode scanning integration in web applications. The MatrixScan technology enhances the speed of barcode and text recognition, making it valuable for industries such as retail, logistics, manufacturing, healthcare, and government. Scandit's solutions are designed to improve operational efficiency by enabling mobile shopping, self-checkout, inventory management, and asset tracking, while also facilitating patient and medication tracking in healthcare settings. The company serves a diverse clientele, including well-known organizations like 7-Eleven, Carrefour, and Toyota, among others, and has additional offices in San Francisco, Boston, London, and Warsaw.

SQZ Biotech is a developer of a cell engineering technology designed to deliver a diverse set of materials into patient cells. It is a privately held company that develops cellular therapies for multiple indications using the proprietary CellSqueeze technology. Through internal research programs and external partnerships, SQZ’s unique cell engineering capabilities are being used to develop a new generation of cell therapies by engineering the immune system both through immune activation and immune suppression for a wide range of clinical challenges.

Owkin is an artificial intelligence company founded in 2016, with headquarters in New York and an additional office in Paris. The company focuses on developing machine learning software for medical research, enabling researchers to test AI models on distributed data. Owkin's offerings include Owkin Lab, which facilitates data connectivity by therapeutic area; Owkin Loop, which provides validated and packaged models; and a comprehensive software stack for full-stack services. The company currently has 30 live models and an additional 40 in development. Owkin aims to empower medical researchers in hospitals, universities, and pharmaceutical companies to better understand variations in drug efficacy among patients, enhance the drug development process, and identify optimal treatments for individual patients, ultimately improving treatment outcomes. The company is supported by various investors and has a scientific board to guide its research initiatives.

Ventus Therapeutics U.S., Inc. is a biopharmaceutical company based in Natick, Massachusetts, with an additional location in Montreal, Canada. Founded in 2019, it focuses on discovering and developing novel small-molecule medicines that target the innate immune system to address autoimmune diseases, inflammatory diseases, and cancer. The company employs a structural immunology platform that integrates protein engineering to elucidate molecular structures and mechanisms of action. This platform facilitates the development of precise binding and functional screening assays, as well as structure-based modeling. Ventus Therapeutics is advancing an emerging pipeline of drug programs aimed at key targets within the innate immune system, leveraging its proprietary capabilities in rational and structure-based drug design.

Cockroach Labs, Inc. specializes in the development of open-source database software, notably CockroachDB, a cloud-native, distributed SQL database designed for modern application development. Founded in 2015 and headquartered in New York, with an additional office in Cambridge, Massachusetts, the company provides a robust solution that combines the functionality of SQL with the horizontal scalability typical of NoSQL systems. CockroachDB is engineered to support strongly-consistent ACID transactions and offers an SQL API for data management. Its architecture ensures minimal latency disruption and resilience against failures across various levels, including disk, machine, rack, and datacenter. Serving a diverse clientele from startups to Fortune 500 companies, Cockroach Labs enables organizations across multiple industries, including banking, retail, and media, to build applications that can scale efficiently and maintain operational continuity.

ROME Therapeutics, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative therapies for cancer and autoimmune diseases. Established in 2019, ROME Therapeutics is pioneering the exploration of the repeatome, which consists of extensive regions of genetic material previously considered "junk DNA." The company has identified several drug targets and is actively advancing multiple discovery programs. To facilitate its research, ROME has assembled a team of experts across various disciplines, including oncology, immunology, virology, and machine learning, to harness this uncharted area of biology for therapeutic advancements.

Accent Therapeutics, Inc. is a biopharmaceutical company based in Lexington, Massachusetts, focused on developing small molecule therapies for oncology through the innovative field of epitranscriptomics. Founded in 2017, the company explores post-transcriptional chemical modifications of RNA, which play a crucial role in regulating proteins essential for cellular growth and differentiation. By precisely targeting RNA-modifying proteins associated with cancer, Accent Therapeutics aims to translate advanced scientific research into effective treatments for patients, ultimately providing new therapeutic options in the fight against cancer.

Cerevance is a developer of novel therapeutics intended to advance new medicines for serious neurological diseases.The company's therapeutics applies it's technology called NETSseq to reveal transcriptional and epigenetic differences between specific cell types in mature human brains, enabling healthcare providers to detect and tackle the early onset of various neurological diseases.

Universe is a mobile-based website builder established in 2014 and headquartered in Brooklyn, New York. The platform aims to empower users to create customized websites quickly and easily, catering to the needs of small business owners and individuals who prefer mobile solutions. By offering a unique approach that eliminates complicated templates, Universe utilizes customizable website filters that allow users to arrange photos, videos, and icons on a grid pattern through a simple drag-and-drop interface. This enables users to build mobile-optimized websites in just minutes using the company's iOS app, providing them with full control over their online presence.

Dandelion Energy offers affordable geothermal heating and cooling installations. Dandelion Energy's home geothermal system replaces your home’s existing air conditioning and heating equipment with a powerful heat pump and safe, underground pipes that move heat between the earth and home. Kathleen Hannun and Rajeez Quazi founded it in 2017, with its headquarters in Palo Alto in California.

EQRx operates as a biotechnology company, focused on re-engineering the process from drug discovery to patient delivery with the goal of offering a market-based solution for the rising cost of medicines. By bringing together stakeholders from across the healthcare system and utilizing the latest advances in science and technology, the company seeks to discover, develop and deliver high-quality, patent-protected medicines more efficiently and cost-effectively than ever before. The company was founded in 2019 and is based in Cambridge, Massachusetts, United States.

TScan Therapeutics is a biopharmaceutical company dedicated to developing innovative T cell therapies to treat various cancers, including liquid tumors and solid tumors. The company focuses on engineering T cell receptor (TCR) therapies, with specific candidates aimed at addressing hematologic malignancies and preventing relapse after hematopoietic stem cell transplantation. TScan utilizes a specialized platform that identifies shared T cell antigens and minimizes off-target effects, enhancing the safety and effectiveness of its treatments. The company’s pipeline includes both liquid tumor therapies and multiplexed TCR-T candidates for solid tumors. Founded in 2018, TScan Therapeutics is headquartered in Waltham, Massachusetts, and comprises a team of experts committed to expanding treatment options for patients with limited therapeutic alternatives.

Merlin Labs is building an autonomous infrastructure for the sky above us, enabling goods, and eventually people, to fly without pilots.

SQZ Biotech is a developer of a cell engineering technology designed to deliver a diverse set of materials into patient cells. It is a privately held company that develops cellular therapies for multiple indications using the proprietary CellSqueeze technology. Through internal research programs and external partnerships, SQZ’s unique cell engineering capabilities are being used to develop a new generation of cell therapies by engineering the immune system both through immune activation and immune suppression for a wide range of clinical challenges.

Kindbody operates a health and tech company intended to offer fertility services and treatments for the modern woman. It offers a full range of services including intrauterine insemination, in-vitro fertilization, donor support, egg freezing, and embryo freezing, enabling women to improve their overall health and wellbeing.

Kindbody operates a health and tech company intended to offer fertility services and treatments for the modern woman. It offers a full range of services including intrauterine insemination, in-vitro fertilization, donor support, egg freezing, and embryo freezing, enabling women to improve their overall health and wellbeing.

Kitchen United, Inc. is a company that provides food production facilities specifically designed for restaurants and food service providers. Founded in 2017 and headquartered in Pasadena, California, it offers shared commercial kitchen spaces along with business intelligence solutions to support entrepreneurial caterers, pop-ups, mobile food vendors, and start-ups. By providing a turnkey solution, Kitchen United helps restaurant brands expand their operations with minimal risk and investment. Its facilities enable these businesses to efficiently produce food for pick-up and delivery, facilitating their entry into the food delivery market. The company operates locations in major cities across the United States, including Austin, Chicago, Los Angeles, San Francisco, New York City, and Scottsdale.

Snyk Ltd. is a software as a service company that assists organizations in identifying and addressing vulnerabilities in open-source dependencies and container images. Founded in 2015 and headquartered in London, Snyk offers a developer-first security platform that includes Snyk Code, which provides static application security testing to enhance security visibility and remediation across various components of modern applications. The platform empowers developers to scan their code for vulnerabilities, offering alerts and guidance on remediation within their existing code editors. Snyk also provides tools for container vulnerability management, application security management, licensing compliance, and infrastructure as code security. By leveraging an internal database of software security flaws, Snyk helps organizations secure their applications throughout the development lifecycle. The company has established a strategic partnership with Rapid7 and operates additional offices in Tel Aviv, Boston, and Ontario.

Cockroach Labs, Inc. specializes in the development of open-source database software, notably CockroachDB, a cloud-native, distributed SQL database designed for modern application development. Founded in 2015 and headquartered in New York, with an additional office in Cambridge, Massachusetts, the company provides a robust solution that combines the functionality of SQL with the horizontal scalability typical of NoSQL systems. CockroachDB is engineered to support strongly-consistent ACID transactions and offers an SQL API for data management. Its architecture ensures minimal latency disruption and resilience against failures across various levels, including disk, machine, rack, and datacenter. Serving a diverse clientele from startups to Fortune 500 companies, Cockroach Labs enables organizations across multiple industries, including banking, retail, and media, to build applications that can scale efficiently and maintain operational continuity.

TScan Therapeutics is a biopharmaceutical company dedicated to developing innovative T cell therapies to treat various cancers, including liquid tumors and solid tumors. The company focuses on engineering T cell receptor (TCR) therapies, with specific candidates aimed at addressing hematologic malignancies and preventing relapse after hematopoietic stem cell transplantation. TScan utilizes a specialized platform that identifies shared T cell antigens and minimizes off-target effects, enhancing the safety and effectiveness of its treatments. The company’s pipeline includes both liquid tumor therapies and multiplexed TCR-T candidates for solid tumors. Founded in 2018, TScan Therapeutics is headquartered in Waltham, Massachusetts, and comprises a team of experts committed to expanding treatment options for patients with limited therapeutic alternatives.

Quartet Health, Inc. develops and operates a cloud based platform that allows communication and collaboration between medical providers with behavioral health providers for patient care. Its platform works with health plans and health systems to provide actionable population insights and reports on behavioral health conditions to improve patient outcomes, as well as provides tools for patient self-management. The company was founded in 2014 and is based in New York, New York.

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Verve Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to reduce the risk of coronary artery disease, a leading cause of death globally. Founded in 2018 and headquartered in Cambridge, Massachusetts, with a research facility in Philadelphia, the company leverages human genetic analysis and gene-editing technologies to create treatments that offer lifelong protection from this condition. Verve has established strategic alliances, including collaborations with Beam Therapeutics to advance delivery technologies targeting cardiovascular issues and with Verily for developing gene editing delivery vehicles. Formerly known as Endcadia, Verve Therapeutics rebranded in September 2019 to reflect its commitment to addressing heart disease through advanced genetic solutions.

Arrakis Therapeutics is a biopharmaceutical company focused on developing innovative drugs that target ribonucleic acid (RNA) to treat a variety of diseases, including cancer and rare genetic disorders. The company employs a unique drug discovery platform that integrates advanced RNA bioinformatics and structural tools, allowing it to identify new RNA targets and create RNA-targeted small molecules (rSMs). Its proprietary pipeline consists of these rSMs aimed at genetically validated targets across multiple disease areas. Additionally, Arrakis offers SHAPEware, a software tool that assists in predicting RNA secondary structures and potential ligand-binding sites. Founded in 2015 and based in Waltham, Massachusetts, Arrakis Therapeutics aims to enhance therapeutic options for patients through its cutting-edge research and development efforts.

Lemonade operates as a full-stack insurance company powered by AI and behavioral economics and driven by social good. It is a licensed insurance carrier, offering homeowners and renters insurance. Lemonade replaces brokers and bureaucracy with bots and machine learning, delivering zero paperwork and instant everything. The company uses artificial intelligence and behavioral economics to set rates for the homes and renters it insures. Lemonade was founded in 2015 and is headquartered in New York, NY, United States.