Intersouth Partners

Intersouth Partners is a venture capital firm based in Durham, North Carolina, specializing in seed and early-stage investments primarily within the technology and life sciences sectors. Established in 1985, the firm has invested in over 100 private companies and manages $780 million across seven limited partnerships, making it one of the largest venture capital funds in the Southeast. Intersouth focuses on technology areas such as software, semiconductors, digital media, clean technology, and security, while in life sciences, it targets medical devices, biopharmaceuticals, and agricultural biotechnology. The firm typically leads or co-leads investment rounds, making initial equity investments ranging from $0.5 million to $8 million, with an average total investment of $12 million per company over multiple financing rounds. It seeks to take a board seat in its portfolio companies and aims for exits within two to six years. Intersouth does not invest in industries such as airline, apparel, or real estate, and primarily focuses on companies located in the Southeast corridor from Baltimore to Florida.

Kay Burgess

CFO

Dennis Dougherty

Managing General Partner

Richard Kent

Venture Partner

Mitch Mumma

General Partner

Mitchell M. Mumma

Managing General Partner

163 past transactions

Advanced Animal Diagnostics

Venture Round in 2021
Advanced Animal Diagnostics, Inc. commercializes proprietary technology for the diagnosis of farm-animal diseases. It uses an animal's own immune response to detect and stage infections to improve the quality of life for producers, processors, animals, and consumers. The company offers QuickSmear, a rapid differential slide to speed and simplify production animal research using differential cell counts; and SCC+ System for early detection of mastitis. Advanced Animal Diagnostics was founded in 2001 and is based in Durham, North Carolina.

Lyra Therapeutics

Series C in 2020
Lyra Therapeutics, Inc. is a clinical-stage therapeutics company that specializes in developing and commercializing innovative drug and delivery solutions for the localized treatment of ear, nose, and throat diseases. Utilizing its proprietary XTreo technology platform, the company aims to deliver medications directly to affected tissues for extended periods with a single administration. Its lead product candidates, LYR-210 and LYR-220, are bioresorbable polymeric matrices designed for non-invasive in-office procedures, providing up to six months of continuous drug therapy specifically for chronic rhinosinusitis. The active ingredient in these formulations is mometasone furoate, which is recognized for its efficacy and safety in various FDA-approved therapies. Founded in 2005 and headquartered in Watertown, Massachusetts, Lyra Therapeutics was formerly known as 480 Biomedical, Inc. before rebranding in July 2018.

CSA Medical

Venture Round in 2019
CSA Medical, Inc. develops and manufactures innovative spray cryotherapy medical devices aimed at the destruction of unwanted tissue in various medical fields, including dermatology, gynecology, and general surgery. The company's flagship product, the truFreeze spray cryotherapy device, utilizes cold liquid nitrogen as a cryosurgical tool, allowing for the targeted destruction of tissue while promoting the regeneration of healthy tissue. Additionally, CSA Medical offers the Rapid AV Spray Kit, which enhances the truFreeze system by reducing the time required for liquid nitrogen application. Founded in 1993 and originally known as Crymed Technologies, the company rebranded to CSA Medical in 2006 and is headquartered in Baltimore, Maryland, with a research and development facility located in Lexington, Massachusetts.

Lyra Therapeutics

Series B in 2018
Lyra Therapeutics, Inc. is a clinical-stage therapeutics company that specializes in developing and commercializing innovative drug and delivery solutions for the localized treatment of ear, nose, and throat diseases. Utilizing its proprietary XTreo technology platform, the company aims to deliver medications directly to affected tissues for extended periods with a single administration. Its lead product candidates, LYR-210 and LYR-220, are bioresorbable polymeric matrices designed for non-invasive in-office procedures, providing up to six months of continuous drug therapy specifically for chronic rhinosinusitis. The active ingredient in these formulations is mometasone furoate, which is recognized for its efficacy and safety in various FDA-approved therapies. Founded in 2005 and headquartered in Watertown, Massachusetts, Lyra Therapeutics was formerly known as 480 Biomedical, Inc. before rebranding in July 2018.

Azalea Health

Series B in 2016
Azalea Health is a prominent provider of cloud-based healthcare technologies and services, catering to health systems, rural health clinics, billing companies, and community hospitals. The company offers a comprehensive suite of integrated solutions, including Electronic Health Records (EHR), Practice Management (PM), Revenue Cycle Management (RCM), and telehealth services. Azalea Health focuses on enhancing patient engagement through its mobile health application and patient health records portal, which are designed to improve workflow and revenue flow for practices of various sizes and specialties. Additionally, the solutions offered by Azalea Health assist clients in meeting regulatory requirements, such as Meaningful Use and ICD-10 standards, thereby streamlining operations and maximizing revenue.

6fusion

Venture Round in 2016
6fusion operates a cloud management platform that transforms public and private cloud resources into a pay-per-use utility model. Utilizing its proprietary Workload Allocation Cube, the company establishes a standardized method for measuring supply and demand of computing resources. This platform serves IT service providers, enterprises, independent software vendors, and infrastructure owners/operators by simplifying Infrastructure-as-a-Service management through a single console. It offers insights into consumption, performance benchmarking, and cost allocation, all while avoiding vendor lock-in. Additionally, 6fusion employs financial intelligence analytics to enhance the economic measurement of IT infrastructure operations, helping organizations analyze utilization rates, consumption patterns, and cost efficiencies effectively.

Locaid

Venture Round in 2015
Locaid, a leading provider in the Location-as-a-Service (LaaS) sector, specializes in cloud-based geolocation services that enable businesses to determine the physical location of customers, employees, or assets almost instantly. With access to over 5 billion connected devices worldwide and mobile location capabilities on more than 360 million devices, Locaid supports enterprises and developers in enhancing productivity, reducing fraud, and gaining valuable consumer insights. The company serves as a key location gateway for major telecommunications carriers in the Americas, making it a preferred partner for numerous global brands, financial institutions, and technology firms. Locaid's Omni-Location™ platform prioritizes privacy and compliance, allowing organizations to leverage location data effectively while ensuring user consent. By providing advanced reporting, geofencing, and messaging services, Locaid equips businesses with the tools necessary to optimize operations and engage customers in a hyper-local context.

CallMiner

Venture Round in 2015
CallMiner, Inc. specializes in providing speech analytics solutions designed to enhance agent performance and improve contact center operations. The company offers a range of products, including the Eureka platform, which enables conversational analytics to uncover insights from interactions between agents and customers. It features tools such as myEureka for automated performance management, Eureka Live for real-time call monitoring, and Eureka Essentials for smaller contact centers. CallMiner's solutions are delivered through both Software-as-a-Service and on-premise installations, catering to various industries including financial services, utilities, manufacturing, and travel. Since its founding in 2002, CallMiner has established a significant presence in the market, with over 2 billion hours of conversations analyzed and a commitment to continuous improvement through customer feedback. The company also provides support services, training programs, and an online community for users. Headquartered in Waltham, Massachusetts, with additional offices in Fort Myers and the United Kingdom, CallMiner remains agile in adapting to the evolving needs of its clients.

Arsenal Medical

Venture Round in 2015
Arsenal Medical, Inc., a platform technology company, develops polymer based foams and fibers for the treatment of vascular diseases. It develops in-situ forming foams to provide local therapy for acute hemorrhage and other critical clinical conditions, including vascular injury and repair. The company also provides AxioCore, a core-sheath nanofiber and microfiber technology constructed from known biomaterials, which is used for cell integration and tissue regeneration enabling controlled delivery of a range of biologics and therapeutics. Arsenal Medical, Inc. was founded in 2005 and is based in Watertown, Massachusetts.

480 Biomedical

Series C in 2015
480 Biomedical focuses on the development of a bioresorbable scaffold for treating occlusive disease in the superficial femoral artery (SFA). Its lead product, SFA scaffold, is a proprietary scaffold and delivery system for use in treating peripheral arterial disease in the SFA. The company was founded in 2011 and is based in Watertown, Massachusetts.

Vascular Pharmaceuticals

Series A in 2015
Vascular Pharmaceuticals, Inc., a biopharmaceutical company, engages in the development of therapeutics for treating patients with type 1 and type 2 diabetes. It focuses on the development of VPI-2690B, a subcutaneously administered monoclonal antibody that is stimulated by hyperglycemia for the treatment of diabetic nephropathy. The company was founded in 2005 and is based in Research Triangle Park, North Carolina.

Azalea Health

Venture Round in 2015
Azalea Health is a prominent provider of cloud-based healthcare technologies and services, catering to health systems, rural health clinics, billing companies, and community hospitals. The company offers a comprehensive suite of integrated solutions, including Electronic Health Records (EHR), Practice Management (PM), Revenue Cycle Management (RCM), and telehealth services. Azalea Health focuses on enhancing patient engagement through its mobile health application and patient health records portal, which are designed to improve workflow and revenue flow for practices of various sizes and specialties. Additionally, the solutions offered by Azalea Health assist clients in meeting regulatory requirements, such as Meaningful Use and ICD-10 standards, thereby streamlining operations and maximizing revenue.

Viamet Pharmaceuticals

Series D in 2014
Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allows them to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.

Proteon Therapeutics

Series D in 2014
Proteon Therapeutics, Inc is a biopharmaceutical company developing pharmaceuticals to address the medical needs of patients with renal and vascular diseases. The company leverages a unique understanding of tissue remodeling to develop a pipeline of proprietary therapeutics. Proteon Therapeutics’ first drug candidate (PRT-201) is in development for the improvement of blood flow following vascular surgery procedures. The company’s initial clinical focus is vascular access for hemodialysis and peripheral arterial disease (PAD).

CSA Medical

Series C in 2013
CSA Medical, Inc. develops and manufactures innovative spray cryotherapy medical devices aimed at the destruction of unwanted tissue in various medical fields, including dermatology, gynecology, and general surgery. The company's flagship product, the truFreeze spray cryotherapy device, utilizes cold liquid nitrogen as a cryosurgical tool, allowing for the targeted destruction of tissue while promoting the regeneration of healthy tissue. Additionally, CSA Medical offers the Rapid AV Spray Kit, which enhances the truFreeze system by reducing the time required for liquid nitrogen application. Founded in 1993 and originally known as Crymed Technologies, the company rebranded to CSA Medical in 2006 and is headquartered in Baltimore, Maryland, with a research and development facility located in Lexington, Massachusetts.

Zenph

Debt Financing in 2013
Learn to play the music you love in the Zenph Online Education Network (ZOEN). We deliver the perfect match between teachers and students through live online music lessons. Whether you’re looking to learn your favorite song, seeking advice on perfecting your technique or searching for the right music teacher for your kids, taking a live online music lesson from one of the ZOEN’s experienced, nationally renowned music teachers is just a matter of a few clicks! The ZOEN is brought to you by Zenph, Inc. – our award winning Re-Performance® technology was named one of the “Best Ideas of the Year” by The New York Times Magazine and has earned us accolades from music lovers and critics the world over, including multiple GRAMMY® nominations. Based in North Carolina’s Research Triangle Park, we are a venture-backed technology company led by a team of music and software professionals with expertise in music education, consumer software, social gaming and entertainment.

Argos Therapeutics

Series E in 2013
Argos Therapeutics, Inc., a biotechnology company, engages in developing immunotherapy treatments for cancer, infectious and autoimmune diseases, and transplantation rejection. The company has clinical trial programs in cancer and human immunodeficiency virus. Its products include AGS-0031 for metastatic renal cell carcinoma; AGS-0041 for HIV; CD83 soluble protein for transplant rejection/autoimmune disorders; Anti IFN-alpha monoclonal antibody2 for lupus; and regulatory T cell therapy3 for autoimmune disorders. The company was formerly known as MERIX Bioscience, Inc. Argos Therapeutics was founded in 1997 and is based in Durham, North Carolina.

PeopleMatter

Series E in 2013
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software designed to enhance the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company provides solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. PeopleMatter offers a comprehensive hire-to-retire system that simplifies the hiring process for hourly and shift workers, enabling managers to source, screen, and onboard employees more efficiently. By streamlining applicant tracking and onboarding, the platform aims to reduce friction in recruiting and improve overall efficiency, engagement, and customer satisfaction within the service industry. In June 2016, PeopleMatter was acquired by Snagajob.

Argos Therapeutics

Series E in 2013
Argos Therapeutics, Inc., a biotechnology company, engages in developing immunotherapy treatments for cancer, infectious and autoimmune diseases, and transplantation rejection. The company has clinical trial programs in cancer and human immunodeficiency virus. Its products include AGS-0031 for metastatic renal cell carcinoma; AGS-0041 for HIV; CD83 soluble protein for transplant rejection/autoimmune disorders; Anti IFN-alpha monoclonal antibody2 for lupus; and regulatory T cell therapy3 for autoimmune disorders. The company was formerly known as MERIX Bioscience, Inc. Argos Therapeutics was founded in 1997 and is based in Durham, North Carolina.

Locaid

Series D in 2013
Locaid, a leading provider in the Location-as-a-Service (LaaS) sector, specializes in cloud-based geolocation services that enable businesses to determine the physical location of customers, employees, or assets almost instantly. With access to over 5 billion connected devices worldwide and mobile location capabilities on more than 360 million devices, Locaid supports enterprises and developers in enhancing productivity, reducing fraud, and gaining valuable consumer insights. The company serves as a key location gateway for major telecommunications carriers in the Americas, making it a preferred partner for numerous global brands, financial institutions, and technology firms. Locaid's Omni-Location™ platform prioritizes privacy and compliance, allowing organizations to leverage location data effectively while ensuring user consent. By providing advanced reporting, geofencing, and messaging services, Locaid equips businesses with the tools necessary to optimize operations and engage customers in a hyper-local context.
Advanced Animal Diagnostics, Inc. commercializes proprietary technology for the diagnosis of farm-animal diseases. It uses an animal's own immune response to detect and stage infections to improve the quality of life for producers, processors, animals, and consumers. The company offers QuickSmear, a rapid differential slide to speed and simplify production animal research using differential cell counts; and SCC+ System for early detection of mastitis. Advanced Animal Diagnostics was founded in 2001 and is based in Durham, North Carolina.

PeopleMatter

Series D in 2013
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software designed to enhance the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company provides solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. PeopleMatter offers a comprehensive hire-to-retire system that simplifies the hiring process for hourly and shift workers, enabling managers to source, screen, and onboard employees more efficiently. By streamlining applicant tracking and onboarding, the platform aims to reduce friction in recruiting and improve overall efficiency, engagement, and customer satisfaction within the service industry. In June 2016, PeopleMatter was acquired by Snagajob.

AGTC

Series B in 2012
Applied Genetic Technologies Corporation is a clinical-stage biotechnology company focused on developing innovative genetic therapies for patients with rare and debilitating diseases. The company is advancing several product candidates in ophthalmology, including treatments for X-linked retinitis pigmentosa, which has completed Phase I/II clinical trials, and achromatopsia, currently in Phase I/II trials. Additionally, AGTC is working on an optogenetic therapy for patients with advanced retinal disease. The company has also initiated a preclinical program in otology and three preclinical programs targeting central nervous system disorders such as frontotemporal dementia, amyotrophic lateral sclerosis, and adrenoleukodystrophy. Collaborations with various organizations, including Synpromics Limited and the University of Florida, support its research efforts. Founded in 1999 and based in Alachua, Florida, AGTC employs advanced gene therapy techniques, aiming to replace defective genes with functional ones, thus improving patient outcomes with long-lasting treatments.

Zenoss

Series C in 2012
Zenoss Inc. develops IT operations and application monitoring solutions, focusing on ensuring the reliability of IT services for large organizations. The company's flagship product, Zenoss Cloud, is a software-as-a-service platform that normalizes machine data to help prevent service disruptions in complex IT environments. Additionally, Zenoss offers VxRail HCI integration, allowing users to monitor entire VxRail deployments as cohesive units. Their solutions cater to various domains, including IT services, virtualization, and network monitoring, and are utilized by industries such as federal, financial, and technology sectors, as well as service providers. Zenoss has established strategic partnerships with notable companies like Accenture and AWS, enhancing its service offerings. Founded in 2005 and headquartered in Austin, Texas, with an office in Coventry, United Kingdom, Zenoss continues to lead in software-defined IT operations by leveraging machine learning to predict and mitigate potential outages, thus reducing downtime and associated costs.

ABT Molecular Imaging

Series C in 2012
ABT Molecular Imaging, based in Knoxville, Tennessee, specializes in medical imaging by designing, manufacturing, and marketing biomarker generator systems and related accessories. The company’s flagship product, the BG-75 Biomarker Generator, produces unit doses of molecular imaging drugs for positron emission tomography (PET) at the point of use, allowing for on-demand generation of PET biomarkers and radioisotopes. This innovative platform incorporates quality control tests and maintains dose records for each generated dose, ensuring high standards in medical imaging. Founded in 2006 by industry experts Ron and Lynda Nutt, ABT Molecular Imaging distributes its products through a global network of sales and service partners.

Vascular Pharmaceuticals

Series A in 2012
Vascular Pharmaceuticals, Inc., a biopharmaceutical company, engages in the development of therapeutics for treating patients with type 1 and type 2 diabetes. It focuses on the development of VPI-2690B, a subcutaneously administered monoclonal antibody that is stimulated by hyperglycemia for the treatment of diabetic nephropathy. The company was founded in 2005 and is based in Research Triangle Park, North Carolina.

Locaid

Private Equity Round in 2012
Locaid, a leading provider in the Location-as-a-Service (LaaS) sector, specializes in cloud-based geolocation services that enable businesses to determine the physical location of customers, employees, or assets almost instantly. With access to over 5 billion connected devices worldwide and mobile location capabilities on more than 360 million devices, Locaid supports enterprises and developers in enhancing productivity, reducing fraud, and gaining valuable consumer insights. The company serves as a key location gateway for major telecommunications carriers in the Americas, making it a preferred partner for numerous global brands, financial institutions, and technology firms. Locaid's Omni-Location™ platform prioritizes privacy and compliance, allowing organizations to leverage location data effectively while ensuring user consent. By providing advanced reporting, geofencing, and messaging services, Locaid equips businesses with the tools necessary to optimize operations and engage customers in a hyper-local context.

Esanex

Venture Round in 2012
Esanex is a drug development company focused on advancing its highly selective, orally active Hsp90 inhibitors. SNX-5422, created from a novel chemical scaffold that is unique in the Hsp90 field, has shown outstanding pre-clinical activity in a number of tumor models and is currently completing Phase 1 trials.

Argos Therapeutics

Series D in 2012
Argos Therapeutics, Inc., a biotechnology company, engages in developing immunotherapy treatments for cancer, infectious and autoimmune diseases, and transplantation rejection. The company has clinical trial programs in cancer and human immunodeficiency virus. Its products include AGS-0031 for metastatic renal cell carcinoma; AGS-0041 for HIV; CD83 soluble protein for transplant rejection/autoimmune disorders; Anti IFN-alpha monoclonal antibody2 for lupus; and regulatory T cell therapy3 for autoimmune disorders. The company was formerly known as MERIX Bioscience, Inc. Argos Therapeutics was founded in 1997 and is based in Durham, North Carolina.
Advanced Animal Diagnostics, Inc. commercializes proprietary technology for the diagnosis of farm-animal diseases. It uses an animal's own immune response to detect and stage infections to improve the quality of life for producers, processors, animals, and consumers. The company offers QuickSmear, a rapid differential slide to speed and simplify production animal research using differential cell counts; and SCC+ System for early detection of mastitis. Advanced Animal Diagnostics was founded in 2001 and is based in Durham, North Carolina.

Adaptivity

Series B in 2012
Adaptivity is the IT Blueprint Company. Founded in late 2007 by veteran IT practitioners who have dedicated their careers to changing the way IT is delivered. Our efforts have resulted in numerous industry awards for leveraging real time infrastructure, virtual datacenters and cloud utility models to deliver business impact. Adaptivity was created to address the design challenges facing enterprise IT. We are leveraging our proven experience, industry partnerships and lessons learned to create a codified intelligent design platform to enable enterprise IT to optimize, re-design and create new systems in a dynamical, virtual and agile manner.

Semprius

Venture Round in 2012
Semprius, Inc. is focused on the design, development, and manufacture of high concentration photovoltaic (HCPV) solar modules aimed at generating solar energy for utility, commercial, and government applications in sunny and arid regions globally. The company utilizes a proprietary micro-transfer printing technology that enhances the performance and reliability of its solar modules while ensuring low production costs and scalability for high-volume output. In addition to its solar offerings, Semprius licenses its micro-transfer printing technology for various non-solar applications, including flat-panel displays, flexible electronics, and large-area sensors, which require lightweight and thin form factors. Founded in 2005 and headquartered in Durham, North Carolina, Semprius aims to make solar power generation more economically viable and supports diverse technology applications through its innovative solutions.

CSA Medical

Series B in 2011
CSA Medical, Inc. develops and manufactures innovative spray cryotherapy medical devices aimed at the destruction of unwanted tissue in various medical fields, including dermatology, gynecology, and general surgery. The company's flagship product, the truFreeze spray cryotherapy device, utilizes cold liquid nitrogen as a cryosurgical tool, allowing for the targeted destruction of tissue while promoting the regeneration of healthy tissue. Additionally, CSA Medical offers the Rapid AV Spray Kit, which enhances the truFreeze system by reducing the time required for liquid nitrogen application. Founded in 1993 and originally known as Crymed Technologies, the company rebranded to CSA Medical in 2006 and is headquartered in Baltimore, Maryland, with a research and development facility located in Lexington, Massachusetts.

simplifyMD

Series A in 2011
simplifyMD, an Alpharetta, GA-based electronic health records (EHR) provider. Founded in 2006, simplifyMD provides physician practices with a ONC-ATCB (Office of the National Coordinator-Authorized Testing and Certification Body) certified, web-based platform that offers EHR, medical-grade document management and Patient Health Record technologies.

480 Biomedical

Series A in 2011
480 Biomedical focuses on the development of a bioresorbable scaffold for treating occlusive disease in the superficial femoral artery (SFA). Its lead product, SFA scaffold, is a proprietary scaffold and delivery system for use in treating peripheral arterial disease in the SFA. The company was founded in 2011 and is based in Watertown, Massachusetts.

Adaptivity

Venture Round in 2011
Adaptivity is the IT Blueprint Company. Founded in late 2007 by veteran IT practitioners who have dedicated their careers to changing the way IT is delivered. Our efforts have resulted in numerous industry awards for leveraging real time infrastructure, virtual datacenters and cloud utility models to deliver business impact. Adaptivity was created to address the design challenges facing enterprise IT. We are leveraging our proven experience, industry partnerships and lessons learned to create a codified intelligent design platform to enable enterprise IT to optimize, re-design and create new systems in a dynamical, virtual and agile manner.

Arsenal Medical

Debt Financing in 2011
Arsenal Medical, Inc., a platform technology company, develops polymer based foams and fibers for the treatment of vascular diseases. It develops in-situ forming foams to provide local therapy for acute hemorrhage and other critical clinical conditions, including vascular injury and repair. The company also provides AxioCore, a core-sheath nanofiber and microfiber technology constructed from known biomaterials, which is used for cell integration and tissue regeneration enabling controlled delivery of a range of biologics and therapeutics. Arsenal Medical, Inc. was founded in 2005 and is based in Watertown, Massachusetts.

6fusion

Series B in 2011
6fusion operates a cloud management platform that transforms public and private cloud resources into a pay-per-use utility model. Utilizing its proprietary Workload Allocation Cube, the company establishes a standardized method for measuring supply and demand of computing resources. This platform serves IT service providers, enterprises, independent software vendors, and infrastructure owners/operators by simplifying Infrastructure-as-a-Service management through a single console. It offers insights into consumption, performance benchmarking, and cost allocation, all while avoiding vendor lock-in. Additionally, 6fusion employs financial intelligence analytics to enhance the economic measurement of IT infrastructure operations, helping organizations analyze utilization rates, consumption patterns, and cost efficiencies effectively.

Proteon Therapeutics

Series C in 2011
Proteon Therapeutics, Inc is a biopharmaceutical company developing pharmaceuticals to address the medical needs of patients with renal and vascular diseases. The company leverages a unique understanding of tissue remodeling to develop a pipeline of proprietary therapeutics. Proteon Therapeutics’ first drug candidate (PRT-201) is in development for the improvement of blood flow following vascular surgery procedures. The company’s initial clinical focus is vascular access for hemodialysis and peripheral arterial disease (PAD).

Semprius

Series C in 2011
Semprius, Inc. is focused on the design, development, and manufacture of high concentration photovoltaic (HCPV) solar modules aimed at generating solar energy for utility, commercial, and government applications in sunny and arid regions globally. The company utilizes a proprietary micro-transfer printing technology that enhances the performance and reliability of its solar modules while ensuring low production costs and scalability for high-volume output. In addition to its solar offerings, Semprius licenses its micro-transfer printing technology for various non-solar applications, including flat-panel displays, flexible electronics, and large-area sensors, which require lightweight and thin form factors. Founded in 2005 and headquartered in Durham, North Carolina, Semprius aims to make solar power generation more economically viable and supports diverse technology applications through its innovative solutions.

PeopleMatter

Series B in 2011
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software designed to enhance the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company provides solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. PeopleMatter offers a comprehensive hire-to-retire system that simplifies the hiring process for hourly and shift workers, enabling managers to source, screen, and onboard employees more efficiently. By streamlining applicant tracking and onboarding, the platform aims to reduce friction in recruiting and improve overall efficiency, engagement, and customer satisfaction within the service industry. In June 2016, PeopleMatter was acquired by Snagajob.
Advanced Animal Diagnostics, Inc. commercializes proprietary technology for the diagnosis of farm-animal diseases. It uses an animal's own immune response to detect and stage infections to improve the quality of life for producers, processors, animals, and consumers. The company offers QuickSmear, a rapid differential slide to speed and simplify production animal research using differential cell counts; and SCC+ System for early detection of mastitis. Advanced Animal Diagnostics was founded in 2001 and is based in Durham, North Carolina.

Locaid

Series C in 2011
Locaid, a leading provider in the Location-as-a-Service (LaaS) sector, specializes in cloud-based geolocation services that enable businesses to determine the physical location of customers, employees, or assets almost instantly. With access to over 5 billion connected devices worldwide and mobile location capabilities on more than 360 million devices, Locaid supports enterprises and developers in enhancing productivity, reducing fraud, and gaining valuable consumer insights. The company serves as a key location gateway for major telecommunications carriers in the Americas, making it a preferred partner for numerous global brands, financial institutions, and technology firms. Locaid's Omni-Location™ platform prioritizes privacy and compliance, allowing organizations to leverage location data effectively while ensuring user consent. By providing advanced reporting, geofencing, and messaging services, Locaid equips businesses with the tools necessary to optimize operations and engage customers in a hyper-local context.

CallMiner

Venture Round in 2010
CallMiner, Inc. specializes in providing speech analytics solutions designed to enhance agent performance and improve contact center operations. The company offers a range of products, including the Eureka platform, which enables conversational analytics to uncover insights from interactions between agents and customers. It features tools such as myEureka for automated performance management, Eureka Live for real-time call monitoring, and Eureka Essentials for smaller contact centers. CallMiner's solutions are delivered through both Software-as-a-Service and on-premise installations, catering to various industries including financial services, utilities, manufacturing, and travel. Since its founding in 2002, CallMiner has established a significant presence in the market, with over 2 billion hours of conversations analyzed and a commitment to continuous improvement through customer feedback. The company also provides support services, training programs, and an online community for users. Headquartered in Waltham, Massachusetts, with additional offices in Fort Myers and the United Kingdom, CallMiner remains agile in adapting to the evolving needs of its clients.

Adaptivity

Series A in 2010
Adaptivity is the IT Blueprint Company. Founded in late 2007 by veteran IT practitioners who have dedicated their careers to changing the way IT is delivered. Our efforts have resulted in numerous industry awards for leveraging real time infrastructure, virtual datacenters and cloud utility models to deliver business impact. Adaptivity was created to address the design challenges facing enterprise IT. We are leveraging our proven experience, industry partnerships and lessons learned to create a codified intelligent design platform to enable enterprise IT to optimize, re-design and create new systems in a dynamical, virtual and agile manner.

CallMiner

Series C in 2010
CallMiner, Inc. specializes in providing speech analytics solutions designed to enhance agent performance and improve contact center operations. The company offers a range of products, including the Eureka platform, which enables conversational analytics to uncover insights from interactions between agents and customers. It features tools such as myEureka for automated performance management, Eureka Live for real-time call monitoring, and Eureka Essentials for smaller contact centers. CallMiner's solutions are delivered through both Software-as-a-Service and on-premise installations, catering to various industries including financial services, utilities, manufacturing, and travel. Since its founding in 2002, CallMiner has established a significant presence in the market, with over 2 billion hours of conversations analyzed and a commitment to continuous improvement through customer feedback. The company also provides support services, training programs, and an online community for users. Headquartered in Waltham, Massachusetts, with additional offices in Fort Myers and the United Kingdom, CallMiner remains agile in adapting to the evolving needs of its clients.

6fusion

Series A in 2010
6fusion operates a cloud management platform that transforms public and private cloud resources into a pay-per-use utility model. Utilizing its proprietary Workload Allocation Cube, the company establishes a standardized method for measuring supply and demand of computing resources. This platform serves IT service providers, enterprises, independent software vendors, and infrastructure owners/operators by simplifying Infrastructure-as-a-Service management through a single console. It offers insights into consumption, performance benchmarking, and cost allocation, all while avoiding vendor lock-in. Additionally, 6fusion employs financial intelligence analytics to enhance the economic measurement of IT infrastructure operations, helping organizations analyze utilization rates, consumption patterns, and cost efficiencies effectively.

Arsenal Medical

Venture Round in 2010
Arsenal Medical, Inc., a platform technology company, develops polymer based foams and fibers for the treatment of vascular diseases. It develops in-situ forming foams to provide local therapy for acute hemorrhage and other critical clinical conditions, including vascular injury and repair. The company also provides AxioCore, a core-sheath nanofiber and microfiber technology constructed from known biomaterials, which is used for cell integration and tissue regeneration enabling controlled delivery of a range of biologics and therapeutics. Arsenal Medical, Inc. was founded in 2005 and is based in Watertown, Massachusetts.

Overture Networks

Venture Round in 2010
Overture Networks develops and manufactures high-speed carrier ethernet edge and aggregation solutions. Its products combine packet-switched and circuit-switched areas into a single architecture-at cost points to offer carrier Ethernet services to any size location over copper, fiber, or optical transport.

PeopleMatter

Venture Round in 2010
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software designed to enhance the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company provides solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. PeopleMatter offers a comprehensive hire-to-retire system that simplifies the hiring process for hourly and shift workers, enabling managers to source, screen, and onboard employees more efficiently. By streamlining applicant tracking and onboarding, the platform aims to reduce friction in recruiting and improve overall efficiency, engagement, and customer satisfaction within the service industry. In June 2016, PeopleMatter was acquired by Snagajob.

ABT Molecular Imaging

Series A in 2010
ABT Molecular Imaging, based in Knoxville, Tennessee, specializes in medical imaging by designing, manufacturing, and marketing biomarker generator systems and related accessories. The company’s flagship product, the BG-75 Biomarker Generator, produces unit doses of molecular imaging drugs for positron emission tomography (PET) at the point of use, allowing for on-demand generation of PET biomarkers and radioisotopes. This innovative platform incorporates quality control tests and maintains dose records for each generated dose, ensuring high standards in medical imaging. Founded in 2006 by industry experts Ron and Lynda Nutt, ABT Molecular Imaging distributes its products through a global network of sales and service partners.

MicroCHIPS

Venture Round in 2010
Microchips Biotech, Inc. is dedicated to improving the lives of patients by revolutionizing drug delivery. Our proprietary microchip-based implant can store and release precise doses of drugs over months and years. The implant, which is placed under the skin by a trained physician during a simple office procedure using local anesthesia, can be wirelessly activated or deactivated by a physician or patient, without requiring removal. In addition, physicians can wirelessly modify the frequency or dose of the drug to meet the individual needs of each patient.

PeopleMatter

Series A in 2009
PeopleMatter, Inc. is a workforce management platform that specializes in talent management software designed to enhance the performance of service-industry brands. Founded in 2001 and based in Charleston, South Carolina, the company provides solutions tailored for various sectors, including technology, transportation, healthcare, government, biotech, and recreation. PeopleMatter offers a comprehensive hire-to-retire system that simplifies the hiring process for hourly and shift workers, enabling managers to source, screen, and onboard employees more efficiently. By streamlining applicant tracking and onboarding, the platform aims to reduce friction in recruiting and improve overall efficiency, engagement, and customer satisfaction within the service industry. In June 2016, PeopleMatter was acquired by Snagajob.

Calibra Medical

Venture Round in 2009
Calibra Medical, Inc. develops medical devices and technologies in the diabetes sector. It offers insulin delivery devices. The company was formerly known as Seattle Medical Technologies, Inc. Calibra Medical, Inc. was founded in 2004 and is based in Redwood City, California.

Zenph Sound Innovations

Series A in 2009
Acquired by Steinway & Sons Inc., January 2015. Zenph Sound Innovations is a developer of musical analysis technology focused on software services and apps related to music. Zenph Sound Innovations offers technology that converts audio recordings into datasets, enabling a virtual artist play re-performances, precisely replicating a musician’s playing in an original recording.

TransEnterix

Post in 2009
TransEnterix, Inc. is a medical device company that focuses on the research, development, and sale of robotic systems designed to enhance minimally invasive surgery. Its primary products include the Senhance System, a multi-port robotic surgery system that utilizes multiple robotic arms for instrument control and camera operation, and the SurgiBot System, a single-port robotically enhanced laparoscopic surgical platform. These systems enable surgeons to perform complex procedures, such as gallbladder removal, with minimal scarring. TransEnterix markets its products directly and through distributors in various regions, including Europe, the United States, Japan, and Taiwan. Founded in 2006, the company is headquartered in Morrisville, North Carolina.

Alimera Sciences

Series C in 2009
Alimera Sciences is a pharmaceutical company that specializes in the research, development, and commercialization of prescription ophthalmic pharmaceuticals. They are presently focused on diseases affecting the back of the eye, or retina because these diseases are not well treated with current therapies and will affect millions of people in their aging populations. It was founded in 2003 and is headquartered in Alpharetta, Georgia.

Viamet Pharmaceuticals

Series B in 2009
Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allows them to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.

AGTC

Venture Round in 2009
Applied Genetic Technologies Corporation is a clinical-stage biotechnology company focused on developing innovative genetic therapies for patients with rare and debilitating diseases. The company is advancing several product candidates in ophthalmology, including treatments for X-linked retinitis pigmentosa, which has completed Phase I/II clinical trials, and achromatopsia, currently in Phase I/II trials. Additionally, AGTC is working on an optogenetic therapy for patients with advanced retinal disease. The company has also initiated a preclinical program in otology and three preclinical programs targeting central nervous system disorders such as frontotemporal dementia, amyotrophic lateral sclerosis, and adrenoleukodystrophy. Collaborations with various organizations, including Synpromics Limited and the University of Florida, support its research efforts. Founded in 1999 and based in Alachua, Florida, AGTC employs advanced gene therapy techniques, aiming to replace defective genes with functional ones, thus improving patient outcomes with long-lasting treatments.

Semprius

Series B in 2009
Semprius, Inc. is focused on the design, development, and manufacture of high concentration photovoltaic (HCPV) solar modules aimed at generating solar energy for utility, commercial, and government applications in sunny and arid regions globally. The company utilizes a proprietary micro-transfer printing technology that enhances the performance and reliability of its solar modules while ensuring low production costs and scalability for high-volume output. In addition to its solar offerings, Semprius licenses its micro-transfer printing technology for various non-solar applications, including flat-panel displays, flexible electronics, and large-area sensors, which require lightweight and thin form factors. Founded in 2005 and headquartered in Durham, North Carolina, Semprius aims to make solar power generation more economically viable and supports diverse technology applications through its innovative solutions.

Cempra

Series C in 2009
Cempra seeks to discover and develop well-differentiated medicines that cure bacterial infections and improve the quality of life for those with chronic illnesses. The company balances near-term product development opportunities, including the macrolide CEM-101, while investing in future products from new technologies to derive the next generation of antibiotics.

Proteon Therapeutics

Series B in 2009
Proteon Therapeutics, Inc is a biopharmaceutical company developing pharmaceuticals to address the medical needs of patients with renal and vascular diseases. The company leverages a unique understanding of tissue remodeling to develop a pipeline of proprietary therapeutics. Proteon Therapeutics’ first drug candidate (PRT-201) is in development for the improvement of blood flow following vascular surgery procedures. The company’s initial clinical focus is vascular access for hemodialysis and peripheral arterial disease (PAD).

Bright View Technologies

Series C in 2009
Bright View Technologies, Inc. is a leading developer of microstructure-based, optical films for the global display industry. They are leveraging patented and proprietary technologies that enable the production of unique optical film products with superior performance characteristics for Plasma, LCD, Rear Projection, Front Projection and OLED.

Ziptronix

Venture Round in 2009
Ziptronix, Inc. designs, develops, and markets semiconductor integration technologies to the electronics industry. The company offers chip stacking, three dimensional integrated circuits, and silicon substrate applications.

Biolex Therapeutics

Series D in 2008
Biolex is a clinical-stage biopharmaceutical company that uses their patented LEX SystemSM to develop hard-to-make therapeutic proteins and monoclonal antibodies that have been optimized to enhance their efficacy and potency. The LEX System is a technology that genetically transforms the aquatic plant Lemna to enable the production of biologic product candidates. Their main product aims at treating those afflicted with Hepatitis C.

Clarabridge

Series C in 2008
Clarabridge is a prominent Customer Experience Management platform that assists leading brands in enhancing their customer experience. The company employs advanced text analytics and enterprise survey tools to analyze various forms of customer feedback. By transforming this feedback into actionable insights, Clarabridge enables businesses to make informed decisions that improve customer satisfaction and engagement. Through its robust solutions, the company empowers organizations to understand their customers better and take decisive actions to elevate their overall experience.

Calibra Medical

Series B in 2008
Calibra Medical, Inc. develops medical devices and technologies in the diabetes sector. It offers insulin delivery devices. The company was formerly known as Seattle Medical Technologies, Inc. Calibra Medical, Inc. was founded in 2004 and is based in Redwood City, California.

Athenix

Series D in 2008
Athenix is a leader in agricultural and industrial biotechnology. They have built the infrastructure necessary to discover new genes and to develop them into products that meet real customer needs.

siXis

Series A in 2008
siXis is a semiconductor company.

Argos Therapeutics

Series C in 2008
Argos Therapeutics, Inc., a biotechnology company, engages in developing immunotherapy treatments for cancer, infectious and autoimmune diseases, and transplantation rejection. The company has clinical trial programs in cancer and human immunodeficiency virus. Its products include AGS-0031 for metastatic renal cell carcinoma; AGS-0041 for HIV; CD83 soluble protein for transplant rejection/autoimmune disorders; Anti IFN-alpha monoclonal antibody2 for lupus; and regulatory T cell therapy3 for autoimmune disorders. The company was formerly known as MERIX Bioscience, Inc. Argos Therapeutics was founded in 1997 and is based in Durham, North Carolina.

Aldagen

Series D in 2008
ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials. Our most advanced product candidate is ALD-101. We are currently conducting a pivotal Phase 3 clinical trial of ALD-101 to evaluate its efficacy in improving umbilical cord blood, or cord blood, transplants used to treat inherited metabolic diseases in pediatric patients. We are also conducting or supporting Phase 1 or Phase 1/2 clinical trials of three other product candidates ALD--151 to improve cord blood transplants used for the treatment of leukemia; ALD-301 to treat critical limb ischemia; and ALD-201 to treat ischemic heart failure.

Alimera Sciences

Series C in 2008
Alimera Sciences is a pharmaceutical company that specializes in the research, development, and commercialization of prescription ophthalmic pharmaceuticals. They are presently focused on diseases affecting the back of the eye, or retina because these diseases are not well treated with current therapies and will affect millions of people in their aging populations. It was founded in 2003 and is headquartered in Alpharetta, Georgia.

Ziptronix

Venture Round in 2008
Ziptronix, Inc. designs, develops, and markets semiconductor integration technologies to the electronics industry. The company offers chip stacking, three dimensional integrated circuits, and silicon substrate applications.

Mixx

Series B in 2008
Mixx is a user-driven social media platform founded by Chris McGill, who previously held positions at Yahoo News and USA Today. Launched in 2007, Mixx allows users to discover and share news tailored to their interests and geographical location, creating a personalized news experience. By enabling users to submit, bookmark, and categorize stories, photos, and videos, Mixx aims to provide a space for both popular and niche publishers, who often struggle for visibility on larger platforms. Each user receives a customized homepage featuring relevant news items, along with access to popular stories and categorized content such as business, sports, and health. Additionally, users can create and join topic-based groups to further refine their news feeds. In an effort to enhance interactivity, Mixx released an API that allows external web services to engage with its content. The platform competes with other emerging social media sites, seeking to carve out its niche in the evolving landscape of online news sharing.

Zenoss

Series B in 2008
Zenoss Inc. develops IT operations and application monitoring solutions, focusing on ensuring the reliability of IT services for large organizations. The company's flagship product, Zenoss Cloud, is a software-as-a-service platform that normalizes machine data to help prevent service disruptions in complex IT environments. Additionally, Zenoss offers VxRail HCI integration, allowing users to monitor entire VxRail deployments as cohesive units. Their solutions cater to various domains, including IT services, virtualization, and network monitoring, and are utilized by industries such as federal, financial, and technology sectors, as well as service providers. Zenoss has established strategic partnerships with notable companies like Accenture and AWS, enhancing its service offerings. Founded in 2005 and headquartered in Austin, Texas, with an office in Coventry, United Kingdom, Zenoss continues to lead in software-defined IT operations by leveraging machine learning to predict and mitigate potential outages, thus reducing downtime and associated costs.

NovaMin Technology

Series C in 2008
NovaMin Technology provides a range of oral hygiene solutions. The company was founded by Randy Scott in 2004 and is based in Alachua, Florida.

nContact

Series C in 2007
nContact is a medical device company founded in 2005 with a mission to develop devices for the endoscopic treatment of arrhythmias, including atrial fibrillation (AF). The Numeris® Coagulation System with VisiTrax® is based on the unique integration of suction, perfusion, and RF energy to ensure the creation of visible, nonconductive, continuous, bi-atrial lesions on the epicardium of a beating heart. To date, the Numeris® Coagulation System with VisiTrax® is indicated for endoscopic coagulation of cardiac tissue in the United States. nContact has initiated IDE clinical studies for the treatment of AF in both open and closed chest procedures. The Numeris Coagulation System with VisiTrax has CE Mark approval in Europe for the coagulation of cardiac tissue for the treatment of AF and atrial flutter.

Arsenal Medical

Series B in 2007
Arsenal Medical, Inc., a platform technology company, develops polymer based foams and fibers for the treatment of vascular diseases. It develops in-situ forming foams to provide local therapy for acute hemorrhage and other critical clinical conditions, including vascular injury and repair. The company also provides AxioCore, a core-sheath nanofiber and microfiber technology constructed from known biomaterials, which is used for cell integration and tissue regeneration enabling controlled delivery of a range of biologics and therapeutics. Arsenal Medical, Inc. was founded in 2005 and is based in Watertown, Massachusetts.

Overture Networks

Series C in 2007
Overture Networks develops and manufactures high-speed carrier ethernet edge and aggregation solutions. Its products combine packet-switched and circuit-switched areas into a single architecture-at cost points to offer carrier Ethernet services to any size location over copper, fiber, or optical transport.

Proteon Therapeutics

Series A in 2007
Proteon Therapeutics, Inc is a biopharmaceutical company developing pharmaceuticals to address the medical needs of patients with renal and vascular diseases. The company leverages a unique understanding of tissue remodeling to develop a pipeline of proprietary therapeutics. Proteon Therapeutics’ first drug candidate (PRT-201) is in development for the improvement of blood flow following vascular surgery procedures. The company’s initial clinical focus is vascular access for hemodialysis and peripheral arterial disease (PAD).

Aldagen

Series C in 2007
ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials. Our most advanced product candidate is ALD-101. We are currently conducting a pivotal Phase 3 clinical trial of ALD-101 to evaluate its efficacy in improving umbilical cord blood, or cord blood, transplants used to treat inherited metabolic diseases in pediatric patients. We are also conducting or supporting Phase 1 or Phase 1/2 clinical trials of three other product candidates ALD--151 to improve cord blood transplants used for the treatment of leukemia; ALD-301 to treat critical limb ischemia; and ALD-201 to treat ischemic heart failure.

Semprius

Series A in 2007
Semprius, Inc. is focused on the design, development, and manufacture of high concentration photovoltaic (HCPV) solar modules aimed at generating solar energy for utility, commercial, and government applications in sunny and arid regions globally. The company utilizes a proprietary micro-transfer printing technology that enhances the performance and reliability of its solar modules while ensuring low production costs and scalability for high-volume output. In addition to its solar offerings, Semprius licenses its micro-transfer printing technology for various non-solar applications, including flat-panel displays, flexible electronics, and large-area sensors, which require lightweight and thin form factors. Founded in 2005 and headquartered in Durham, North Carolina, Semprius aims to make solar power generation more economically viable and supports diverse technology applications through its innovative solutions.

Cempra

Series B in 2007
Cempra seeks to discover and develop well-differentiated medicines that cure bacterial infections and improve the quality of life for those with chronic illnesses. The company balances near-term product development opportunities, including the macrolide CEM-101, while investing in future products from new technologies to derive the next generation of antibiotics.

Serenex

Series D in 2007
Serenex is a medical drug discovery and development company that focuses on oncology. The company develops Hsp90 product platform that provides a collection of small molecule Hsp90 inhibitors for cancer, inflammatory diseases, fungal infection resistance, viral diseases, and neurodegenerative diseases, such as Alzheimer's. It also develops SNX-1012, a product for oral mucositis in solid tumor patients. Serenex is a U.S.-based company that was founded in 2000 and it was acquired in 2008 by Pfizer.

Argolyn Bioscience

Series A in 2007
Argolyn Bioscience is a biotechnology company that develops peptide drug candidates to treat serious diseases and disorders. The company’s products are based on amino acid analog substitution technology. The company's products include ABS201 for schizophrenia and ABS212 for pain.

Mixx

Series A in 2007
Mixx is a user-driven social media platform founded by Chris McGill, who previously held positions at Yahoo News and USA Today. Launched in 2007, Mixx allows users to discover and share news tailored to their interests and geographical location, creating a personalized news experience. By enabling users to submit, bookmark, and categorize stories, photos, and videos, Mixx aims to provide a space for both popular and niche publishers, who often struggle for visibility on larger platforms. Each user receives a customized homepage featuring relevant news items, along with access to popular stories and categorized content such as business, sports, and health. Additionally, users can create and join topic-based groups to further refine their news feeds. In an effort to enhance interactivity, Mixx released an API that allows external web services to engage with its content. The platform competes with other emerging social media sites, seeking to carve out its niche in the evolving landscape of online news sharing.

Viamet Pharmaceuticals

Series A in 2007
Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allows them to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.

Biolex Therapeutics

Series C in 2007
Biolex is a clinical-stage biopharmaceutical company that uses their patented LEX SystemSM to develop hard-to-make therapeutic proteins and monoclonal antibodies that have been optimized to enhance their efficacy and potency. The LEX System is a technology that genetically transforms the aquatic plant Lemna to enable the production of biologic product candidates. Their main product aims at treating those afflicted with Hepatitis C.

FlatBurger

Series A in 2007
FlatBurger, Inc. provides business infrastructure for supporting software developers working in hybrid software environments. It offers business infrastructure to complement the development tools employed in the Microsoft visual studio environment. The company focuses on serving the DotNetNuke community of software developers. FlatBurger, Inc. is based in Loudonville, New York with additional offices in northern Virginia and Troy.

Defywire

Venture Round in 2007
Defywire, Inc. develops wireless connections between teachers, administrators, students, and parents. The company offers Mobile Guardian, a web-based administration console that allows centralized management of mobile users, applications, and school configuration information. Its Mobile Guardian provides access to critical information, reconnecting through cellular, wireless fidelity, satellite, LAN or WAN, or other communication protocols, as well as supports blackberry and various Windows mobile devices, XP desktops, notebooks, and tablet PC's. The company was founded in 2003 and is based in Reston, Virginia.

6th Sense Analytics

Series A in 2007
6th Sense Analytics provides software solutions for automated collection and analysis of software engineering process and product data. The company was founded in 2004 and is based in Morrisville, North Carolina. As of January 12, 2009, 6th Sense Analytics operates as a subsidiary of Rally Software Development Corp.

Clarabridge

Series B in 2007
Clarabridge is a prominent Customer Experience Management platform that assists leading brands in enhancing their customer experience. The company employs advanced text analytics and enterprise survey tools to analyze various forms of customer feedback. By transforming this feedback into actionable insights, Clarabridge enables businesses to make informed decisions that improve customer satisfaction and engagement. Through its robust solutions, the company empowers organizations to understand their customers better and take decisive actions to elevate their overall experience.

Ziptronix

Series D in 2007
Ziptronix, Inc. designs, develops, and markets semiconductor integration technologies to the electronics industry. The company offers chip stacking, three dimensional integrated circuits, and silicon substrate applications.

Aldagen

Series C in 2006
ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. We have four product candidates in clinical trials. Our most advanced product candidate is ALD-101. We are currently conducting a pivotal Phase 3 clinical trial of ALD-101 to evaluate its efficacy in improving umbilical cord blood, or cord blood, transplants used to treat inherited metabolic diseases in pediatric patients. We are also conducting or supporting Phase 1 or Phase 1/2 clinical trials of three other product candidates ALD--151 to improve cord blood transplants used for the treatment of leukemia; ALD-301 to treat critical limb ischemia; and ALD-201 to treat ischemic heart failure.

Jacket Micro Devices

Venture Round in 2006
Jacket Micro Devices provides services and solutions for wireless modules. It offers a platform technology that reduces the size and cost of the radio frequency (RF) components used in wireless devices. The company also provides modules, design services, and substrates for integrated wireless products. In addition, it offers multi-layer organic (MLO) and low temperature laminated organic (LTLO) technologies for wireless system-in-package (SiP) designs. Jacket Micro Devices, Inc. was founded in 2004 and is based in Atlanta, Georgia.

nContact

Series B in 2006
nContact is a medical device company founded in 2005 with a mission to develop devices for the endoscopic treatment of arrhythmias, including atrial fibrillation (AF). The Numeris® Coagulation System with VisiTrax® is based on the unique integration of suction, perfusion, and RF energy to ensure the creation of visible, nonconductive, continuous, bi-atrial lesions on the epicardium of a beating heart. To date, the Numeris® Coagulation System with VisiTrax® is indicated for endoscopic coagulation of cardiac tissue in the United States. nContact has initiated IDE clinical studies for the treatment of AF in both open and closed chest procedures. The Numeris Coagulation System with VisiTrax has CE Mark approval in Europe for the coagulation of cardiac tissue for the treatment of AF and atrial flutter.

Zenoss

Series A in 2006
Zenoss Inc. develops IT operations and application monitoring solutions, focusing on ensuring the reliability of IT services for large organizations. The company's flagship product, Zenoss Cloud, is a software-as-a-service platform that normalizes machine data to help prevent service disruptions in complex IT environments. Additionally, Zenoss offers VxRail HCI integration, allowing users to monitor entire VxRail deployments as cohesive units. Their solutions cater to various domains, including IT services, virtualization, and network monitoring, and are utilized by industries such as federal, financial, and technology sectors, as well as service providers. Zenoss has established strategic partnerships with notable companies like Accenture and AWS, enhancing its service offerings. Founded in 2005 and headquartered in Austin, Texas, with an office in Coventry, United Kingdom, Zenoss continues to lead in software-defined IT operations by leveraging machine learning to predict and mitigate potential outages, thus reducing downtime and associated costs.

COVEGA

Venture Round in 2006
Covega Corporation has established world-class proprietary technologies in InP and LiNbO3 to produce high performance optical devices and modules at a low cost with very small footprints. With early focus on the telecom, datacom and CATV industries, Covega now generates over one-third of its revenue from serving the defense, medical, industrial and instrumentation industries.

CallMiner

Series B in 2006
CallMiner, Inc. specializes in providing speech analytics solutions designed to enhance agent performance and improve contact center operations. The company offers a range of products, including the Eureka platform, which enables conversational analytics to uncover insights from interactions between agents and customers. It features tools such as myEureka for automated performance management, Eureka Live for real-time call monitoring, and Eureka Essentials for smaller contact centers. CallMiner's solutions are delivered through both Software-as-a-Service and on-premise installations, catering to various industries including financial services, utilities, manufacturing, and travel. Since its founding in 2002, CallMiner has established a significant presence in the market, with over 2 billion hours of conversations analyzed and a commitment to continuous improvement through customer feedback. The company also provides support services, training programs, and an online community for users. Headquartered in Waltham, Massachusetts, with additional offices in Fort Myers and the United Kingdom, CallMiner remains agile in adapting to the evolving needs of its clients.

Nitronex

Venture Round in 2006
Nitronex, founded in 1999 by graduates of the wide bandgap program at North Carolina State University, is headquartered in Durham, North Carolina. The company specializes in the development and manufacturing of gallium nitride-on-silicon (GaN-on-Si) RF power devices, establishing itself as a global leader in this technology. Nitronex holds 21 patents and has 17 additional patents pending, reflecting its commitment to innovation in the field of RF power devices.