Osiris Therapeutics, Inc. is a biotechnology company specializing in regenerative medicine, focusing on the development and marketing of cellular products aimed at treating various medical conditions, including those related to inflammation, cardiovascular health, orthopedics, and wound healing. The company operates through two main segments: Therapeutics and Biosurgery. Its Therapeutics segment emphasizes the development of biologic stem cell drug candidates sourced from readily available and non-controversial materials. Osiris markets its products under several brand names, including Grafix, GrafixPL, Stravix, Cartiform, and BIO4. Founded in 1992 and based in Columbia, Maryland, Osiris has established partnerships with organizations such as the Department of Veterans Affairs, Department of Defense, Howmedica Osteonics Corp., and Mesoblast Limited. As of April 2019, Osiris operates as a subsidiary of Smith & Nephew plc, enhancing its capacity to improve patient health while aiming to reduce overall healthcare costs.