Spruce Capital Partners

Spruce Capital Partners is a California-based private equity firm that focuses on venture opportunities within the biogreentech sector. The firm was established by experienced investors and thought leaders who have collaborated for over a decade, bringing extensive expertise in guiding entrepreneurs to develop successful biogreentech companies. In addition to managing venture funds, Spruce Capital Partners is dedicated to nurturing new talent in the industry, fostering innovation, and providing strategic insights. The firm's principals are actively involved in advising and shaping the life sciences sector on a global scale, with a particular emphasis on markets in Malaysia and the United States.

Ganesh Kishore

Managing Partner

Roger Wyse

Managing Partner

Greg Young

Managing Partner

20 past transactions

Amfora

Series B in 2021
Amfora is an emerging leader in the use of biotechnology to address the rapidly growing global demand for protein. Amfora is working to develop nutritionally enhanced forage crops for a market expected to have an annual value of as much as $12 billion a year. The company is based in San Francisco, California and is a portfolio company of Spruce Capital Partners LLC/MLS II Fund.

Provivi

Private Placement in 2017
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Inscripta

Private Placement in 2018
Inscripta, Inc. operates as a gene editing technology company. The company engages in developing CRISPR enzymes (MADzymes) for precision gene editing. Inscripta, Inc. was formerly known as Muse Biotechnology, Inc. The company was founded in 2015 and is based in Boulder, Colorado. It has additional offices in Pleasanton and San Diego, California.

Provivi

Private Placement in 2020
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Gevo

Series D in 2010
Gevo, Inc. operates as a renewable fuels company. It commercializes gasoline, jet fuel, and diesel fuel to achieve zero carbon emissions, and reduce greenhouse gas emissions with sustainable alternatives. The company uses low-carbon renewable-resource-based carbohydrates as raw materials and is developing renewable electricity and renewable natural gas for use in production processes. It products also include renewable biodiesel, isooctane, isobutanol, sustainable aviation fuel, isobutylene, ethanol, and animal feed. The company was formerly known as Methanotech, Inc. and changed its name to Gevo, Inc. in March 2006. Gevo, Inc. was founded in 2005 and is headquartered in Englewood, Colorado.

Provivi

Series C in 2020
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Pivot Bio

Private Placement in 2020
Pivot Bio, Inc. operates as a biotechnology company that provides genome-scale programming of microbes. The company was founded in 2010 and is based in Emeryville, California.

Crop Enhancement

Series B in 2020
Crop Enhancement LLC, an early stage specialty materials company, develops anchoring and controlled-release formulation technologies for agricultural chemicals. The company’s formulation technologies enable release of chemical agents, such as pesticides, herbicides, and fertilizers into target microenvironments. Crop Enhancement LLC was founded in 2011 and is based in San Jose, California.
GreenLight Biosciences, Inc., a biotechnology company, develops RNA-based solutions for agriculture and pharmaceutical applications. The company provides technology for the biological conversion of renewable substrates to valuable products. It offers Unconstrained Metabolism, a technology platform that delivers solutions for the production of chemicals and fuels from renewable resources. It also engages in developing mRNA-based vaccine candidates to potentially prevent individuals from contracting SARS-CoV-2. The company also provides research and analysis services. GreenLight Biosciences, Inc. was incorporated in 2008 and is based in Medford, Massachusetts. It has an additional location in North Carolina.

Evolve Biosystems

Private Placement in 2018
Evolve Biosystems is a biotechnology company that specializes in providing microbiome-based products designed to develop, restore, and maintain. The company's platform focuses on solving the gut dysbiosis throughout the human life cycle as well as in various animal species, enabling physicians to maintain the healthy gut microbiome in newborn infants with a consumer-directed home use product, and a hospital-based neonatal ICU product. It was founded in 2011 and headquartered in Davis, California.

Pivot Bio

Series C in 2020
Pivot Bio, Inc. operates as a biotechnology company that provides genome-scale programming of microbes. The company was founded in 2010 and is based in Emeryville, California.

Provivi

Series B in 2017
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Crop Enhancement

Private Placement in 2020
Crop Enhancement LLC, an early stage specialty materials company, develops anchoring and controlled-release formulation technologies for agricultural chemicals. The company’s formulation technologies enable release of chemical agents, such as pesticides, herbicides, and fertilizers into target microenvironments. Crop Enhancement LLC was founded in 2011 and is based in San Jose, California.

Provivi

Series C in 2019
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Amfora

Series A in 2017
Amfora is an emerging leader in the use of biotechnology to address the rapidly growing global demand for protein. Amfora is working to develop nutritionally enhanced forage crops for a market expected to have an annual value of as much as $12 billion a year. The company is based in San Francisco, California and is a portfolio company of Spruce Capital Partners LLC/MLS II Fund.

Provivi

Private Placement in 2019
Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Evolve Biosystems

Series B in 2017
Evolve Biosystems is a biotechnology company that specializes in providing microbiome-based products designed to develop, restore, and maintain. The company's platform focuses on solving the gut dysbiosis throughout the human life cycle as well as in various animal species, enabling physicians to maintain the healthy gut microbiome in newborn infants with a consumer-directed home use product, and a hospital-based neonatal ICU product. It was founded in 2011 and headquartered in Davis, California.

Inscripta

Series C in 2018
Inscripta, Inc. operates as a gene editing technology company. The company engages in developing CRISPR enzymes (MADzymes) for precision gene editing. Inscripta, Inc. was formerly known as Muse Biotechnology, Inc. The company was founded in 2015 and is based in Boulder, Colorado. It has additional offices in Pleasanton and San Diego, California.

Inscripta

Series B in 2017
Inscripta, Inc. operates as a gene editing technology company. The company engages in developing CRISPR enzymes (MADzymes) for precision gene editing. Inscripta, Inc. was formerly known as Muse Biotechnology, Inc. The company was founded in 2015 and is based in Boulder, Colorado. It has additional offices in Pleasanton and San Diego, California.