Spruce Capital Partners

Developer of a team formation platform designed to help companies adapt and build tech in areas outside of their core competencies. The company's platform is an invite-only community of independent tech talent with diverse expertise and backgrounds that help companies pivot their product and adapt to new methods of monetization by building to share and team up on meaningful missions, enabling companies to quickly connect and form a full-stack team.

GreenLight Biosciences is a biotechnology company that specializes in RNA-based solutions for agricultural and pharmaceutical applications. Founded in 2008 and headquartered in Medford, Massachusetts, with an additional location in North Carolina, the company utilizes its Unconstrained Metabolism technology platform to convert renewable substrates into valuable chemicals and fuels. This platform allows for significant flexibility and control in the production process. GreenLight is also focused on developing RNA products aimed at improving crop management, plant protection, and animal health, while advancing vaccine development and pandemic preparedness. In addition to these applications, the company is working on mRNA-based vaccine candidates targeting seasonal and pandemic influenza, as well as other emerging viruses, to enhance public health. Through its innovations, GreenLight aims to provide sustainable solutions that contribute to global food security and health.

Amfora is an emerging leader in the use of biotechnology to address the rapidly growing global demand for protein. Amfora is working to develop nutritionally enhanced forage crops for a market expected to have an annual value of as much as $12 billion a year. The company is based in San Francisco, California and is a portfolio company of Spruce Capital Partners LLC/MLS II Fund.

Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Pivot Bio is a biotechnology company founded in 2010 and based in Emeryville, California. The company specializes in advancing crop nutrition through a deep understanding of the microbiome. By leveraging engineering principles and data science, Pivot Bio develops innovative solutions that utilize naturally occurring microbes to enhance crop yield and quality. Their proprietary ON Technology aims to provide essential nutrients to crops, specifically focusing on enabling microbes to fix and supply nitrogen for corn. This approach seeks to offer a sustainable alternative to traditional chemical fertilizers and pesticides, helping farmers improve their yields while addressing the nutritional needs of the growing global population. Through collaboration and communication, Pivot Bio is dedicated to transforming agricultural practices and contributing to a healthier planet.

Crop Enhancement LLC, an early stage specialty materials company, develops anchoring and controlled-release formulation technologies for agricultural chemicals. The company’s formulation technologies enable release of chemical agents, such as pesticides, herbicides, and fertilizers into target microenvironments. Crop Enhancement LLC was founded in 2011 and is based in San Jose, California.

Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Inscripta, Inc. is a gene editing technology company focused on developing advanced CRISPR enzymes, specifically MADzymes, for precision gene editing. Founded in 2015 and headquartered in Boulder, Colorado, with additional offices in Pleasanton and San Diego, Inscripta aims to revolutionize genome engineering through its innovative benchtop platform. This platform integrates an instrument, consumables, software, and assays to facilitate fully automated and scalable editing of single cells, enabling researchers to conduct massively parallel experiments with unprecedented efficiency. By offering tools that simplify the editing process and making its MAD7 CRISPR nuclease available for research, Inscripta seeks to empower scientists in overcoming existing technical and licensing barriers, fostering a new era of biological discovery.

Provivi Inc. develops biopesticides for agriculture, commercial, household, and public health pest management. It develops research quantities of carbene/nitrene transferase enzymes that activate diazo and azide compounds to generate iron-carbenoids and iron-nitrenoids through a mode of activation. The company also develops a biocatalysis and fermentation technology, which is based on biocatalysts that enable efficient synthesis of biopesticides. Its technology has applications in industries, such as pharmaceuticals, nutrition, flavors, and fragrances. The company offers its products through distributors worldwide. Provivi Inc. was incorporated in 2012 and is based in Santa Monica, California.

Evolve Biosystems is a biotechnology company that specializes in providing microbiome-based products designed to develop, restore, and maintain. The company's platform focuses on solving the gut dysbiosis throughout the human life cycle as well as in various animal species, enabling physicians to maintain the healthy gut microbiome in newborn infants with a consumer-directed home use product, and a hospital-based neonatal ICU product. It was founded in 2011 and headquartered in Davis, California.

Amfora is an emerging leader in the use of biotechnology to address the rapidly growing global demand for protein. Amfora is working to develop nutritionally enhanced forage crops for a market expected to have an annual value of as much as $12 billion a year. The company is based in San Francisco, California and is a portfolio company of Spruce Capital Partners LLC/MLS II Fund.

Inscripta, Inc. is a gene editing technology company focused on developing advanced CRISPR enzymes, specifically MADzymes, for precision gene editing. Founded in 2015 and headquartered in Boulder, Colorado, with additional offices in Pleasanton and San Diego, Inscripta aims to revolutionize genome engineering through its innovative benchtop platform. This platform integrates an instrument, consumables, software, and assays to facilitate fully automated and scalable editing of single cells, enabling researchers to conduct massively parallel experiments with unprecedented efficiency. By offering tools that simplify the editing process and making its MAD7 CRISPR nuclease available for research, Inscripta seeks to empower scientists in overcoming existing technical and licensing barriers, fostering a new era of biological discovery.

Gevo, Inc. operates as a renewable fuels company. It commercializes gasoline, jet fuel, and diesel fuel to achieve zero carbon emissions, and reduce greenhouse gas emissions with sustainable alternatives. The company uses low-carbon renewable-resource-based carbohydrates as raw materials and is developing renewable electricity and renewable natural gas for use in production processes. It products also include renewable biodiesel, isooctane, isobutanol, sustainable aviation fuel, isobutylene, ethanol, and animal feed. The company was formerly known as Methanotech, Inc. and changed its name to Gevo, Inc. in March 2006. Gevo, Inc. was founded in 2005 and is headquartered in Englewood, Colorado.