Principia SGR is an Italian venture capital firm established in 2002, managing over EUR 80 million in assets. The firm focuses on early-stage investments in small and mid-sized technology companies, primarily within Italy. Principia operates two funds that target digital startups and expansion capital opportunities, with a particular interest in seed investments in select cases.
Silk Biomaterials is an Italian based medical device startup founded by four life sciences professionals. The proprietary technology platform is based on pure silk fibroin and targets a wide range of clinical needs, from regenerative medicine to drug release applications. As of 2018, it's about to enter the clinic with a first-in-human trial on a nerve guide application. The rich R&D pipeline is advancing in parallel several assets: bone grafting, bladder drug release, vascular grafting, etc.
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.
Enterome SA is a biotechnology company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, it specializes in disease management solutions that leverage its understanding of the gut microbiome. The company focuses on developing biomarkers, companion diagnostics, and therapeutics aimed at treating various microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. Enterome's innovative approach involves identifying bioactive molecules differentially expressed by the gut microbiome, which are crucial for regulating human physiology and immune responses. The company has established a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts. By integrating its expertise in the gut microbiome with therapeutic development, Enterome aims to create targeted solutions for complex health challenges.
COMPASS Pathways is a mental health care company focused on developing innovative treatments for mental health conditions. It specializes in the formulation of COMP360, a psilocybin-based therapy currently undergoing Phase IIb clinical trials aimed at treating patients with treatment-resistant depression. The company operates across multiple sites in Europe and North America, conducting large-scale clinical trials to evaluate the efficacy and safety of its psilocybin therapy. Founded in 2016 and incorporated in 2020, COMPASS Pathways is headquartered in Altrincham, Cheshire, United Kingdom. The company's mission is to enhance patient access to evidence-based mental health solutions.
ComfTech s.r.l. develops and markets wearable monitoring systems based on sensorized garments for the babies. The company’s product includes new born monitoring system which offers unique and wireless solution for the newborns. It enables accurate measurement of a range of physiological parameters and offer reliable, continuous, and non-invasive monitoring. ComfTech s.r.l. was founded in 2010 and is headquartered in Monza, Italy.
CrestOptics specializes in the development of advanced microscopy instruments primarily for fluorescence microscopy. The company focuses on creating high-performance optical and electrooptical systems tailored to meet the needs of both the research community and industrial applications. Based in Rome, Italy, CrestOptics benefits from proximity to numerous prestigious research institutions, allowing for collaboration on innovative projects, such as those with CNR – FISBAT, which aim to enhance technologies for live cell imaging and laser-activated experiments. With over 15 years of experience in the field, CrestOptics leverages the expertise of its partner company, Crisel Instruments, to provide customized services and solutions that improve sensitivity, image quality, and clarity, addressing the growing demands of scientific inquiry and industrial research.
Enterome SA is a biotechnology company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, it specializes in disease management solutions that leverage its understanding of the gut microbiome. The company focuses on developing biomarkers, companion diagnostics, and therapeutics aimed at treating various microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. Enterome's innovative approach involves identifying bioactive molecules differentially expressed by the gut microbiome, which are crucial for regulating human physiology and immune responses. The company has established a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts. By integrating its expertise in the gut microbiome with therapeutic development, Enterome aims to create targeted solutions for complex health challenges.
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.
Enterome SA is a biotechnology company based in Paris, France, with an additional office in Cambridge, Massachusetts. Founded in 2008, it specializes in disease management solutions that leverage its understanding of the gut microbiome. The company focuses on developing biomarkers, companion diagnostics, and therapeutics aimed at treating various microbiome-related diseases, including inflammatory bowel diseases and metabolic disorders. Enterome's innovative approach involves identifying bioactive molecules differentially expressed by the gut microbiome, which are crucial for regulating human physiology and immune responses. The company has established a strategic collaboration with Takeda Pharmaceutical Company to enhance its research and development efforts. By integrating its expertise in the gut microbiome with therapeutic development, Enterome aims to create targeted solutions for complex health challenges.
AnaBios specializes in enabling human-focused drug discovery. As a CRO, AnaBios provides products and services for every stage of drug discovery. Through proprietary technology based on the use of human donor organs and tissues, it studies ex vivo human responses to drugs and further investigate the molecular and functional basis of relevant human physiology. Its research focuses primarily on the areas of high, unmet medical need, including cardiac disease and safety, pain, PKD kidney disease, and neurodegeneration.
In partnership with Fortune 500 pharmaceutical companies, contract research organizations, and universities, the company's mission is to develop therapeutic advancements to help patients live longer, healthier, and more productive lives.
Pedius srl provides a communication system to enable the deaf to make phone calls. It offers Pedius, an application for iPhone and Android that allows hearing impaired people to make normal phone calls using speech recognition and synthesis technologies. The company offers Pedius in Italian, English, and Spanish languages. Pedius srl is based in Rome, Italy.
Ixaltis SA is a specialty pharmaceutical company based in Archamps, France, focused on developing therapeutics for genitourinary tract disorders that have significant unmet medical needs. Founded in 2012, the company leverages the expertise of a team comprising scientists and pharmaceutical professionals to identify and repurpose drugs that have already reached clinical stages for new applications in this field. Its product pipeline includes IXA-001, an oral mixed serotonin agonist-antagonist, IXA-002, an MAO A-B inhibitor, and IXA-003, an MAO B inhibitor, each targeting specific genitourinary conditions. Through its innovative approach, Ixaltis aims to provide effective treatments for patients suffering from these disorders.
RigeneranD is committed to develop biomedical devices supporting the culture of stem cells for pre-clinical and clinical applications.Founded in 2009 by Prof. Massimo Dominici and Prof. Pierfranco Conte, as a spin-off resulting from a joint venture between biomedical company RanD and researchers from the University of Modena and Reggio Emilia, Rigenerand owns proprietary technology to develop and produce biomedical tools to empower the ex-vivo phase of stem cells expansion combining the need of high cell yield with innovative biocompatible materials.
Silk Biomaterials is an Italian based medical device startup founded by four life sciences professionals. The proprietary technology platform is based on pure silk fibroin and targets a wide range of clinical needs, from regenerative medicine to drug release applications. As of 2018, it's about to enter the clinic with a first-in-human trial on a nerve guide application. The rich R&D pipeline is advancing in parallel several assets: bone grafting, bladder drug release, vascular grafting, etc.
Comecer S.P.A. is a prominent Italian company specializing in the design and manufacture of products and solutions for nuclear medicine, isolation technologies, and nuclear power plant equipment. Established in 1974 and headquartered in Castel Bolognese, Italy, the company develops a range of systems including hot cells, dispensing systems, and workflow management tools for radiopharmaceuticals. Its isolation technology solutions encompass aseptic containment and laboratory isolators, while its nuclear power plant offerings include shielded transport containers and waste management equipment. Comecer serves a diverse clientele that includes hospitals, universities, research institutions, and pharmaceutical companies, providing tailored solutions for the handling of toxic and hazardous substances. The company operates production sites in Italy and Holland, with additional locations in the Czech Republic, Germany, the United States, India, and China, and it markets its products through a direct sales network.
DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.
Tacatì, an Asti, Italy-based online grocery shopping platform. Created in 2012 by Giulia Valente and Stefano Cravero, Tacatì allows users to do grocery shopping online and receive local bio products at home, office or wherever they want. They can pay either online or at the time of receipt of items.
Affaredelgiorno provides online discount coupons on food and non-food products. Antonio Folino founded it in 2013, with its headquarters in Itá in Brazil.
Rysto srl operates a social platform designed to connect job-seekers with employers in the food and beverage service industry, facilitating recruitment and training processes. Founded in 2013 and based in Naples, Italy, Rysto offers job listings and hiring services across various roles, including bartenders, chefs, waitstaff, and hotel personnel. The platform also provides online training courses aimed at enhancing staff skills, ensuring compliance with food regulations, and obtaining necessary certifications such as occupational HACCP. By offering geo-located, real-time solutions, Rysto addresses staffing challenges such as employee absences and fluctuating demand in the hospitality sector, positioning itself as a key player in the restaurant and hospitality labor market.
Weekend-a-gogo is a company based in Naples, Italy, specializing in offering weekend packages for tourists. These packages are designed to enhance the travel experience by providing curated options that cater to various interests and preferences. The company focuses on creating memorable weekend getaways, allowing visitors to explore the rich culture and attractions of the region. By targeting both local and international tourists, Weekend-a-gogo aims to capitalize on the growing demand for short-term travel experiences.
D-Share is an international company focused on digital publishing and media. Combining technological skills, comprehensive expertise in publishing business and unparalleled experience, D-Share collaborates with clients to explore new, advanced business models based on next generation technologies. We provide worldwide publishers with end-to-end solutions, user experience development and services through our offices in Italy (D-Share Srl) and the United States of America (D-Share U.S.A., Corp.).
DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).
im3D specializes in developing advanced technologies for 3D screening, particularly in cancer prevention. The company employs proprietary algorithms and methodologies rooted in extensive scientific, clinical, and technical research. With a commitment to collaboration, im3D works closely with doctors and researchers to identify their needs and create innovative diagnostic and investigative tools. These tools are designed to be less invasive, more flexible, reliable, and user-friendly, thereby enhancing the overall diagnostic process. Since its inception, im3D has prioritized high-quality standards and continuous improvement, ensuring both the development of effective solutions and the satisfaction of its customers.
im3D specializes in developing advanced technologies for 3D screening, particularly in cancer prevention. The company employs proprietary algorithms and methodologies rooted in extensive scientific, clinical, and technical research. With a commitment to collaboration, im3D works closely with doctors and researchers to identify their needs and create innovative diagnostic and investigative tools. These tools are designed to be less invasive, more flexible, reliable, and user-friendly, thereby enhancing the overall diagnostic process. Since its inception, im3D has prioritized high-quality standards and continuous improvement, ensuring both the development of effective solutions and the satisfaction of its customers.
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.
Bangbite S.r.l. offers online soccer management games. It provides OFootball, website and mobile phone application game about management of a virtual football team. The company was founded in 2009 and is based in Sassari, Italy.
Jusp S.p.A. offers mobile-POS solutions and value-added services. The company offers a card reader that can be connected via a mini jack audio lead to any smart device; and an application, which receives data and manages the transaction process. It serves merchants, small businesses, and large corporations. The company was founded in 2011 and is headquartered in Cagliari, Italy.
StreetLib (www.streetlib.com) is a publishing facilitator and a global gateway to the $143 billion international book market, 70% of which is happening outside the USA, for publishers big and small.
Whether you are an independent author or a multinational publisher, StreetLib offers unrivalled global reach through our worldwide network of retail, digital library and subscription service outlets.
StreetLib distributes ebooks, audiobooks, comics, magazines and print-on-demand paperbacks. StreetLib’s standard model is no up-front fees and it takes just a 10% commission per sale made.
Itsworld Sicilia
Venture Round in 2012
Itsworld Sicilia operates digital system that monitors photovoltaic facilities. The company is based in Milan, Italy.
Eco4Cloud S.R.L. offers a solution to reduce power consumption of data centers. It analyzes user’s data center or cloud infrastructure; feeds simulator with data for analyses; and balances the load among the servers and prevents overload events. The company was founded in 2011 and is based in Rende, Italy.
4w MarketPlace è il network pubblicitario leader del mercato digitale italiano.
Con oltre 12.000 editori, 500 siti web e mobile tra i più prestigiosi, raggiunge una reach pari al 70%, e un volume di impression mensili di oltre 7 miliardi. offre agli investitori pubblicitari un range completo di formati native per desktop, tablet e smartphone – dagli annunci contestuali, ai video, ai formati display – utilizzando una suite proprietaria che integra le migliori tecnologie disponibili. dal 2009 gestisce in esclusiva spazi adv sui siti del consorzio premium publisher network (ppn), fondato da gruppo rcs e gruppo editoriale l’espresso.
A cloud-based service that allows any company to provide live support to online customers.
Vivocha enables businesses to seamlessly communicate with prospects and customers right on the website, using any combination of VoIP (audio and video), chat, audio callbacks and collaboration tools, like assisted browsing, form & document sharing.
Vivocha.com is the simplest and most effective multi-channel online customer engagement service.
Online customer interactions made easy
Moneyfarm is an independent financial services provider operating in Italy, Germany, and the United Kingdom, offering online financial advisory and execution services. Founded in 2011 and headquartered in Milan, with an additional office in Cagliari, the company enables users to create and manage diversified investment portfolios tailored to their individual investor profiles, which are determined through an online questionnaire. Moneyfarm's platform facilitates investment in index funds and allows clients to track their investments and receive personalized advice. Revenue is generated solely from client fees, as the company does not accept back-end fees or commissions from financial institutions, ensuring transparency in its services. The platform aims to provide an efficient and cost-effective way for users to grow and protect their wealth.
Eco4Cloud S.R.L. offers a solution to reduce power consumption of data centers. It analyzes user’s data center or cloud infrastructure; feeds simulator with data for analyses; and balances the load among the servers and prevents overload events. The company was founded in 2011 and is based in Rende, Italy.
6sicuro S.p.A. is an insurance brokerage company based in Milan, Italy, specializing in online insurance comparison services. Established in 2000, the company operates a digital platform that allows users to compare free quotes from various partner insurance companies and purchase suitable insurance policies directly online. The platform facilitates comparisons for a wide range of insurance products, including car, motorcycle, truck, life, travel, marriage, home, mobile phone, and mortgage insurance. Additionally, 6sicuro provides information and advice on related services such as ADSL, pay TV, tires, and auto liability rates. With an additional office located in Selargius, the company aims to simplify the insurance purchasing process for consumers in Italy.
Neodata Group is an Italian company that specializes in optimizing digital content delivery for online dealers and publishers. Founded in 2004 and headquartered in Milan, with additional offices in Catania and Los Angeles, Neodata offers a comprehensive suite of solutions, including advanced ad-serving technologies, personalized news delivery systems, and content performance alert systems. Its products, such as the Articles Recommendation System and Neo-TM text-mining engine, utilize proprietary algorithms and semantic analysis to recommend content to readers based on their preferences and behaviors. Neodata's platform effectively collects and analyzes diverse data to create detailed audience profiles, enabling publishers to engage their audience with tailored marketing messages and enhance content relevance.
Docebo Inc. is a provider of a cloud-based learning management system (LMS) designed to enhance training for external workforces, partners, and customers across North America, Europe, and the Asia-Pacific region. Established in 2005 and headquartered in Toronto, Canada, Docebo offers a comprehensive platform that centralizes and organizes learning materials, facilitating the training process and improving productivity. Key components of its platform include Docebo Learn, which enables administrators to manage content and track certifications; Docebo Discover, Coach & Share, which promotes personalized and social learning; and Docebo Extended Enterprise, which supports multiple audience portals. The company also features integrations like Docebo for Salesforce and provides a mobile application platform, AI-powered virtual coaching, and tools for creating customized learning environments. Docebo serves various industries, including technology, media, manufacturing, and retail, catering to the needs of midsize to large organizations globally.
Neodata Group is an Italian company that specializes in optimizing digital content delivery for online dealers and publishers. Founded in 2004 and headquartered in Milan, with additional offices in Catania and Los Angeles, Neodata offers a comprehensive suite of solutions, including advanced ad-serving technologies, personalized news delivery systems, and content performance alert systems. Its products, such as the Articles Recommendation System and Neo-TM text-mining engine, utilize proprietary algorithms and semantic analysis to recommend content to readers based on their preferences and behaviors. Neodata's platform effectively collects and analyzes diverse data to create detailed audience profiles, enabling publishers to engage their audience with tailored marketing messages and enhance content relevance.
Applix, founded in 2010, specializes in mobile solutions tailored for brands, publishers, and institutions seeking to establish a digital presence. The company focuses on two primary areas: Digital Publishing and Mobile & Apps. In Digital Publishing, Applix transforms traditional paper-based publications into interactive digital editions accessible on smartphones, tablets, and computers, while also enabling clients to monitor reader engagement. In the Mobile & Apps sector, the company develops customized mobile solutions to meet specific client needs, leveraging its technological expertise and innovation. Applix has expanded its capabilities through acquisitions, including Xorovo, which specializes in mobile solutions, and bSmart, focused on digital publishing for educational purposes. Its applications have garnered international recognition, with millions of downloads across more than 120 countries, achieving top rankings in app stores in over 50 regions.
GADA Spa offers cardiovascular, blood and infusion management, and critical and intensive care product technology solutions. The company offers integrated healthcare services. It serves hospital centers. The company was founded in 2005 and is based in Rome, Italy.
Citynews is an Italian-based network of local newspaper websites, currently operating in nine cities with plans to expand to the 30 largest cities in Italy. The platform produces daily news stories and offers editions that are accessible online from any device, allowing readers and local communities to stay informed and share knowledge. With approximately 1.4 million monthly visits, Citynews serves as a vital source of information for its audience, focusing on issues relevant to various Italian provinces.
X2TV is owned by Beeweeb and participated by Quantica Sgr – Venture Capital through the Principia II fund. Beeweeb is a privately-owned company that has designed and developed Mobile and web 2.0 solutions for over 10 years. X2TV board of directors is composed by Giampiero Recco (Chairman), Enrico Donati (Chief Executive Officer) and Stefano Peroncini (Quantica SGR). The board of statutory auditors is composed by Giovanni Pinna Parpaglia (President) Andrea Bonelli and Marco Gramegna. X2TV’s first partner to launch an “augmented†TV broadcast in Italy was RAI with Voyager, hosted by Roberto Giacobbo at dinner time. Incorporated in November 2010, X2TV Srl is dedicated to the digital entertainment service X2TV; it was born as a spinoff of Beeweeb S.p.A. with the goal of developing and managing the service given in partnership with TV broadcasters. The Headquarters is located in Roma, via Giacomo Peroni 400/402. X2TV department is located in Sardinia Technology Park.
Altilia S.r.l. is a provider of a cloud-based data management platform known as MANTRA, which transforms big data into smart data for organizations. The platform enables users to collect, consolidate, and manage both structured and unstructured data from diverse sources to enhance decision-making and streamline business processes. MANTRA employs advanced algorithms and natural language processing techniques for tasks such as semantic data annotation, sentiment analysis, and data integration. Its applications cater to various industries, including finance, healthcare, telecommunications, and eCommerce, addressing needs like fraud detection, risk profiling, and cyber security. By offering a user-friendly interface and extensive API capabilities, Altilia's platform supports organizations in automating operational processes and improving data-driven insights. Founded in 2010 and based in Rende, Italy, Altilia has gained recognition for its innovative solutions in the field of data management.
Kee Square S.r.l., based in Milano, Italy, specializes in the design and development of advanced techniques for video and audio signal processing. The company focuses on biometric identification and tracking, as well as the detection of hazardous events and security applications. Its product lineup includes Morpheus AC, which provides physical access protection through facial analysis; Morpheus PC, aimed at securing logical access to workstations via video camera facial recognition; Morpheus SDK, a software development kit for building and comparing biometric templates; and Morpheus ICAO, which evaluates facial images to ensure compliance with specific requirements. Kee Square caters primarily to law enforcement and commercial markets, offering tailored solutions to meet their unique security needs.
Correlec engages in searching, extracting, updating, and classifying data originating from various sources and grouping it into logical categories. The company is headquartered in Legnano, Italy.
Dialectica
Series A in 2006
Dialectica is a biotechnological company that produces neuronal cellular models. The company was founded in 2004 and is based in Milan, Italy.