Principia SGR

Principia SGR is an Italian venture capital firm established in 2002, managing over EUR 80 million in assets. The firm focuses on early-stage investments in small and mid-sized technology companies, primarily within Italy. Principia operates two funds that target digital startups and expansion capital opportunities, with a particular interest in seed investments in select cases.

Alessandro Damiano

Fund Manager

Michele Fodde

Investment Manager

Past deals in Italy

KLISBio

Convertible Note in 2021
Silk Biomaterials is an Italian based medical device startup founded by four life sciences professionals. The proprietary technology platform is based on pure silk fibroin and targets a wide range of clinical needs, from regenerative medicine to drug release applications. As of 2018, it's about to enter the clinic with a first-in-human trial on a nerve guide application. The rich R&D pipeline is advancing in parallel several assets: bone grafting, bladder drug release, vascular grafting, etc.

WISE

Series C in 2020
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.

ComfTech s.r.l.

Venture Round in 2018
ComfTech s.r.l. develops and markets wearable monitoring systems based on sensorized garments for the babies. The company’s product includes new born monitoring system which offers unique and wireless solution for the newborns. It enables accurate measurement of a range of physiological parameters and offer reliable, continuous, and non-invasive monitoring. ComfTech s.r.l. was founded in 2010 and is headquartered in Monza, Italy.

CrestOptics

Venture Round in 2018
CrestOptics specializes in the development of advanced microscopy instruments primarily for fluorescence microscopy. The company focuses on creating high-performance optical and electrooptical systems tailored to meet the needs of both the research community and industrial applications. Based in Rome, Italy, CrestOptics benefits from proximity to numerous prestigious research institutions, allowing for collaboration on innovative projects, such as those with CNR – FISBAT, which aim to enhance technologies for live cell imaging and laser-activated experiments. With over 15 years of experience in the field, CrestOptics leverages the expertise of its partner company, Crisel Instruments, to provide customized services and solutions that improve sensitivity, image quality, and clarity, addressing the growing demands of scientific inquiry and industrial research.

Clinical Trial Center S.P.A.

Venture Round in 2017
Clinical Trial Center S.P.A. offers clinic research and trial services.

TRIFARMA SpA

Acquisition in 2017
TRIFARMA SpA manufactures and distributes active pharmaceutical ingredients (APIs). Its product categories includes anti-osteoporosis, progestogen, expectorant, antipneumocystic, anticonvulsant, cr3+ supplement, glucocorticoid, antibacterial, antidepressant, anthelmintic, antigonadotropin, antiparkinsonian, antihistaminic, antineoplastic, antipsychotic, antiviral, diuretic, solvent, anti-inflammatory, analgesic, cardiotonic, antihypertensive, antianginal, androgen, narcotic, uricosuric, antiemetic, androgen, antidiabetic, and anticoagulant.

WISE

Series B in 2017
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.

Pedius

Series A in 2016
Pedius srl provides a communication system to enable the deaf to make phone calls. It offers Pedius, an application for iPhone and Android that allows hearing impaired people to make normal phone calls using speech recognition and synthesis technologies. The company offers Pedius in Italian, English, and Spanish languages. Pedius srl is based in Rome, Italy.

Rigenerand Srl

Venture Round in 2016
RigeneranD is committed to develop biomedical devices supporting the culture of stem cells for pre-clinical and clinical applications.Founded in 2009 by Prof. Massimo Dominici and Prof. Pierfranco Conte, as a spin-off resulting from a joint venture between biomedical company RanD and researchers from the University of Modena and Reggio Emilia, Rigenerand owns proprietary technology to develop and produce biomedical tools to empower the ex-vivo phase of stem cells expansion combining the need of high cell yield with innovative biocompatible materials.

KLISBio

Series A in 2016
Silk Biomaterials is an Italian based medical device startup founded by four life sciences professionals. The proprietary technology platform is based on pure silk fibroin and targets a wide range of clinical needs, from regenerative medicine to drug release applications. As of 2018, it's about to enter the clinic with a first-in-human trial on a nerve guide application. The rich R&D pipeline is advancing in parallel several assets: bone grafting, bladder drug release, vascular grafting, etc.

Comecer

Venture Round in 2015
Comecer S.P.A. is a prominent Italian company specializing in the design and manufacture of products and solutions for nuclear medicine, isolation technologies, and nuclear power plant equipment. Established in 1974 and headquartered in Castel Bolognese, Italy, the company develops a range of systems including hot cells, dispensing systems, and workflow management tools for radiopharmaceuticals. Its isolation technology solutions encompass aseptic containment and laboratory isolators, while its nuclear power plant offerings include shielded transport containers and waste management equipment. Comecer serves a diverse clientele that includes hospitals, universities, research institutions, and pharmaceutical companies, providing tailored solutions for the handling of toxic and hazardous substances. The company operates production sites in Italy and Holland, with additional locations in the Czech Republic, Germany, the United States, India, and China, and it markets its products through a direct sales network.

DoveConviene

Series C in 2015
DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).

WISE

Series A in 2015
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.

WISE

Venture Round in 2014
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.

Tacatì

Seed Round in 2013
Tacatì, an Asti, Italy-based online grocery shopping platform. Created in 2012 by Giulia Valente and Stefano Cravero, Tacatì allows users to do grocery shopping online and receive local bio products at home, office or wherever they want. They can pay either online or at the time of receipt of items.

Rysto

Venture Round in 2013
Rysto srl operates a social platform designed to connect job-seekers with employers in the food and beverage service industry, facilitating recruitment and training processes. Founded in 2013 and based in Naples, Italy, Rysto offers job listings and hiring services across various roles, including bartenders, chefs, waitstaff, and hotel personnel. The platform also provides online training courses aimed at enhancing staff skills, ensuring compliance with food regulations, and obtaining necessary certifications such as occupational HACCP. By offering geo-located, real-time solutions, Rysto addresses staffing challenges such as employee absences and fluctuating demand in the hospitality sector, positioning itself as a key player in the restaurant and hospitality labor market.

Weekend-a-gogo

Seed Round in 2013
Weekend-a-gogo is a company based in Naples, Italy, specializing in offering weekend packages for tourists. These packages are designed to enhance the travel experience by providing curated options that cater to various interests and preferences. The company focuses on creating memorable weekend getaways, allowing visitors to explore the rich culture and attractions of the region. By targeting both local and international tourists, Weekend-a-gogo aims to capitalize on the growing demand for short-term travel experiences.

D-Share

Venture Round in 2013
D-Share is an international company focused on digital publishing and media. Combining technological skills, comprehensive expertise in publishing business and unparalleled experience, D-Share collaborates with clients to explore new, advanced business models based on next generation technologies. We provide worldwide publishers with end-to-end solutions, user experience development and services through our offices in Italy (D-Share Srl) and the United States of America (D-Share U.S.A., Corp.).

DoveConviene

Series A in 2013
DoveConviene S.R.L. designs and develops a digital platform which helps people to shop by saving money through offers and leaflets presented georeferenced manner. The company was founded in 2010 and is based in Sestu, Italy. The startup trades under the brand DoveConviene in Italy and ShopFully in the U.S., as well as various other names in Spain, Brazil, Mexico and Indonesia (TechCrunch).

im3D

Seed Round in 2013
im3D specializes in developing advanced technologies for 3D screening, particularly in cancer prevention. The company employs proprietary algorithms and methodologies rooted in extensive scientific, clinical, and technical research. With a commitment to collaboration, im3D works closely with doctors and researchers to identify their needs and create innovative diagnostic and investigative tools. These tools are designed to be less invasive, more flexible, reliable, and user-friendly, thereby enhancing the overall diagnostic process. Since its inception, im3D has prioritized high-quality standards and continuous improvement, ensuring both the development of effective solutions and the satisfaction of its customers.

im3D

Venture Round in 2013
im3D specializes in developing advanced technologies for 3D screening, particularly in cancer prevention. The company employs proprietary algorithms and methodologies rooted in extensive scientific, clinical, and technical research. With a commitment to collaboration, im3D works closely with doctors and researchers to identify their needs and create innovative diagnostic and investigative tools. These tools are designed to be less invasive, more flexible, reliable, and user-friendly, thereby enhancing the overall diagnostic process. Since its inception, im3D has prioritized high-quality standards and continuous improvement, ensuring both the development of effective solutions and the satisfaction of its customers.

WISE

Venture Round in 2013
WISE Srl, established in 2011 and headquartered in Milan, Italy, specializes in the manufacture of implantable biomedical devices for biotechnology and biomedicine applications. The company employs advanced supersonic cluster beam implantation technology to integrate biocompatible, flexible, and stretchable conductive micro-electrodes into polymers, particularly elastomers. This innovative approach is primarily utilized in developing leads for neurostimulation, which are implanted in the spinal cord or brain to address neurodegenerative conditions such as chronic pain and Parkinson's disease. WISE aims to create a new generation of neuromodulation leads that are unbreakable, less invasive, and more cost-effective, enhancing treatment options for patients.

Bangbite

Venture Round in 2013
Bangbite S.r.l. offers online soccer management games. It provides OFootball, website and mobile phone application game about management of a virtual football team. The company was founded in 2009 and is based in Sassari, Italy.

Jusp

Series A in 2013
Jusp S.p.A. offers mobile-POS solutions and value-added services. The company offers a card reader that can be connected via a mini jack audio lead to any smart device; and an application, which receives data and manages the transaction process. It serves merchants, small businesses, and large corporations. The company was founded in 2011 and is headquartered in Cagliari, Italy.

Itsworld Sicilia

Venture Round in 2012
Itsworld Sicilia operates digital system that monitors photovoltaic facilities. The company is based in Milan, Italy.

eco4cloud

Venture Round in 2012
Eco4Cloud S.R.L. offers a solution to reduce power consumption of data centers. It analyzes user’s data center or cloud infrastructure; feeds simulator with data for analyses; and balances the load among the servers and prevents overload events. The company was founded in 2011 and is based in Rende, Italy.

4w MarketPlace

Venture Round in 2012
4w MarketPlace è il network pubblicitario leader del mercato digitale italiano. Con oltre 12.000 editori, 500 siti web e mobile tra i più prestigiosi, raggiunge una reach pari al 70%, e un volume di impression mensili di oltre 7 miliardi. offre agli investitori pubblicitari un range completo di formati native per desktop, tablet e smartphone – dagli annunci contestuali, ai video, ai formati display – utilizzando una suite proprietaria che integra le migliori tecnologie disponibili. dal 2009 gestisce in esclusiva spazi adv sui siti del consorzio premium publisher network (ppn), fondato da gruppo rcs e gruppo editoriale l’espresso.

CicerOOs

Series A in 2012
CicerOOs (beta) is the funniest way to promote destinations and their attractions all over the world!

Moneyfarm

Venture Round in 2012
Moneyfarm is an independent financial services provider operating in Italy, Germany, and the United Kingdom, offering online financial advisory and execution services. Founded in 2011 and headquartered in Milan, with an additional office in Cagliari, the company enables users to create and manage diversified investment portfolios tailored to their individual investor profiles, which are determined through an online questionnaire. Moneyfarm's platform facilitates investment in index funds and allows clients to track their investments and receive personalized advice. Revenue is generated solely from client fees, as the company does not accept back-end fees or commissions from financial institutions, ensuring transparency in its services. The platform aims to provide an efficient and cost-effective way for users to grow and protect their wealth.

eco4cloud

Seed Round in 2012
Eco4Cloud S.R.L. offers a solution to reduce power consumption of data centers. It analyzes user’s data center or cloud infrastructure; feeds simulator with data for analyses; and balances the load among the servers and prevents overload events. The company was founded in 2011 and is based in Rende, Italy.

6sicuro

Venture Round in 2012
6sicuro S.p.A. is an insurance brokerage company based in Milan, Italy, specializing in online insurance comparison services. Established in 2000, the company operates a digital platform that allows users to compare free quotes from various partner insurance companies and purchase suitable insurance policies directly online. The platform facilitates comparisons for a wide range of insurance products, including car, motorcycle, truck, life, travel, marriage, home, mobile phone, and mortgage insurance. Additionally, 6sicuro provides information and advice on related services such as ADSL, pay TV, tires, and auto liability rates. With an additional office located in Selargius, the company aims to simplify the insurance purchasing process for consumers in Italy.

Neodata Group

Venture Round in 2012
Neodata Group is an Italian company that specializes in optimizing digital content delivery for online dealers and publishers. Founded in 2004 and headquartered in Milan, with additional offices in Catania and Los Angeles, Neodata offers a comprehensive suite of solutions, including advanced ad-serving technologies, personalized news delivery systems, and content performance alert systems. Its products, such as the Articles Recommendation System and Neo-TM text-mining engine, utilize proprietary algorithms and semantic analysis to recommend content to readers based on their preferences and behaviors. Neodata's platform effectively collects and analyzes diverse data to create detailed audience profiles, enabling publishers to engage their audience with tailored marketing messages and enhance content relevance.

Neodata Group

Venture Round in 2012
Neodata Group is an Italian company that specializes in optimizing digital content delivery for online dealers and publishers. Founded in 2004 and headquartered in Milan, with additional offices in Catania and Los Angeles, Neodata offers a comprehensive suite of solutions, including advanced ad-serving technologies, personalized news delivery systems, and content performance alert systems. Its products, such as the Articles Recommendation System and Neo-TM text-mining engine, utilize proprietary algorithms and semantic analysis to recommend content to readers based on their preferences and behaviors. Neodata's platform effectively collects and analyzes diverse data to create detailed audience profiles, enabling publishers to engage their audience with tailored marketing messages and enhance content relevance.

Applix

Series A in 2011
Applix, founded in 2010, specializes in mobile solutions tailored for brands, publishers, and institutions seeking to establish a digital presence. The company focuses on two primary areas: Digital Publishing and Mobile & Apps. In Digital Publishing, Applix transforms traditional paper-based publications into interactive digital editions accessible on smartphones, tablets, and computers, while also enabling clients to monitor reader engagement. In the Mobile & Apps sector, the company develops customized mobile solutions to meet specific client needs, leveraging its technological expertise and innovation. Applix has expanded its capabilities through acquisitions, including Xorovo, which specializes in mobile solutions, and bSmart, focused on digital publishing for educational purposes. Its applications have garnered international recognition, with millions of downloads across more than 120 countries, achieving top rankings in app stores in over 50 regions.

GADA

Venture Round in 2011
GADA Spa offers cardiovascular, blood and infusion management, and critical and intensive care product technology solutions. The company offers integrated healthcare services. It serves hospital centers. The company was founded in 2005 and is based in Rome, Italy.

Citynews

Series A in 2011
Citynews is an Italian-based network of local newspaper websites, currently operating in nine cities with plans to expand to the 30 largest cities in Italy. The platform produces daily news stories and offers editions that are accessible online from any device, allowing readers and local communities to stay informed and share knowledge. With approximately 1.4 million monthly visits, Citynews serves as a vital source of information for its audience, focusing on issues relevant to various Italian provinces.

X2TV

Venture Round in 2010
X2TV is owned by Beeweeb and participated by Quantica Sgr – Venture Capital through the Principia II fund. Beeweeb is a privately-owned company that has designed and developed Mobile and web 2.0 solutions for over 10 years. X2TV board of directors is composed by Giampiero Recco (Chairman), Enrico Donati (Chief Executive Officer) and Stefano Peroncini (Quantica SGR). The board of statutory auditors is composed by Giovanni Pinna Parpaglia (President) Andrea Bonelli and Marco Gramegna. X2TV’s first partner to launch an “augmented” TV broadcast in Italy was RAI with Voyager, hosted by Roberto Giacobbo at dinner time. Incorporated in November 2010, X2TV Srl is dedicated to the digital entertainment service X2TV; it was born as a spinoff of Beeweeb S.p.A. with the goal of developing and managing the service given in partnership with TV broadcasters. The Headquarters is located in Roma, via Giacomo Peroni 400/402. X2TV department is located in Sardinia Technology Park.

Altilia

Venture Round in 2010
Altilia S.r.l. is a provider of a cloud-based data management platform known as MANTRA, which transforms big data into smart data for organizations. The platform enables users to collect, consolidate, and manage both structured and unstructured data from diverse sources to enhance decision-making and streamline business processes. MANTRA employs advanced algorithms and natural language processing techniques for tasks such as semantic data annotation, sentiment analysis, and data integration. Its applications cater to various industries, including finance, healthcare, telecommunications, and eCommerce, addressing needs like fraud detection, risk profiling, and cyber security. By offering a user-friendly interface and extensive API capabilities, Altilia's platform supports organizations in automating operational processes and improving data-driven insights. Founded in 2010 and based in Rende, Italy, Altilia has gained recognition for its innovative solutions in the field of data management.

Kee Square

Venture Round in 2008
Kee Square S.r.l., based in Milano, Italy, specializes in the design and development of advanced techniques for video and audio signal processing. The company focuses on biometric identification and tracking, as well as the detection of hazardous events and security applications. Its product lineup includes Morpheus AC, which provides physical access protection through facial analysis; Morpheus PC, aimed at securing logical access to workstations via video camera facial recognition; Morpheus SDK, a software development kit for building and comparing biometric templates; and Morpheus ICAO, which evaluates facial images to ensure compliance with specific requirements. Kee Square caters primarily to law enforcement and commercial markets, offering tailored solutions to meet their unique security needs.

Correlec

Venture Round in 2006
Correlec engages in searching, extracting, updating, and classifying data originating from various sources and grouping it into logical categories. The company is headquartered in Legnano, Italy.

Dialectica

Series A in 2006
Dialectica is a biotechnological company that produces neuronal cellular models. The company was founded in 2004 and is based in Milan, Italy.