Medical Excellence Capital

Medical Excellence Capital is an early-stage venture capital firm based in Nissequogue, New York, founded in 2020. It focuses on investing in the life sciences sector, specifically targeting drug discovery, artificial intelligence, machine learning, cell and gene therapy, synthetic biology, regenerative medicine, and precision medicine. The firm leverages a unique global network of physician scientists, combined with a team of experienced investors and operators, to identify and support innovative companies in the United States and Canada. As a Registered Investment Adviser, Medical Excellence Capital aims to drive advancements in healthcare through strategic investments in emerging technologies and therapeutic solutions.

Kevin Emesiani

Senior Associate

Eric Heil

Managing Partner

Kim Kamdar Ph.D

Managing Partner

Joni Mancini

Managing Partner

John Prufeta

Founder, CEO, General Partner and Managing Partner

3 past transactions

Pleno

Seed Round in 2022
Developer of a multi-omic instrument designed for biological target detection for clinical testing and biomedical research. The company's platform provides monitoring of minimal residual disease and early multi-cancer screening, also detects a diverse collection of analytical targets that includes DNA, RNA, and protein biomarkers with unprecedented speed and precision, and leverages advanced microfluidics to automate all aspects of sample preparation and analysis, enabling healthcare providers to get access to diverse health monitoring technologies.

Aspen Neuroscience

Series B in 2022
Aspen Neuroscience, Inc. is a biotechnology company based in San Diego, California, focused on developing induced pluripotent stem cell therapies for neurological conditions, particularly Parkinson's disease. Founded in 2018, the company aims to create patient-specific restorative cell therapies that can alter the progression of the disease. Its product pipeline includes ANPD001, an autologous neuron replacement therapy designed for sporadic Parkinson's disease, and ANPD002, a gene-edited version targeting familial forms of the disease. By integrating innovative genomic approaches with stem cell biology, Aspen Neuroscience seeks to advance the field of personalized medicine and improve treatment outcomes for patients suffering from Parkinson's disease.

Immunitas Therapeutics

Series B in 2021
Immunitas Therapeutics, Inc. is focused on developing targeted therapies for cancer patients through innovative single-cell analyses. Founded in 2019 and based in Cambridge, Massachusetts, the company utilizes a single-cell sequencing platform to explore the biology of immune cells within human tumors. This approach allows Immunitas to identify novel drug targets rooted in human biology and create key biomarkers that assist in selecting patients who may benefit from their therapies. By translating laboratory findings into clinical applications, Immunitas aims to address longstanding challenges in oncology and improve treatment options for complex cancers. The company is advancing multiple programs toward early human studies, leveraging expertise in antibody discovery and engineering to develop effective treatments.
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