Khosla Ventures

AliveCor has a device and application that will turn any smartphone into a clinical-quality electrocardiogram (ECG) recorder. AliveCor is pioneering the creation of FDA-cleared 'machine learning' techniques to enable proactive heart care and is recognized around the world for transforming cardiac care. It specializes in the fields of healthcare, mobile device, and medicine. It was founded in 2010 and headquartered in Mountain View, California.

Loop Health is a healthcare provider based in Pune, India, founded in 2018. The company offers a range of services including acute and urgent care, chronic condition management, women's health, health coaching, and preventive care. Loop Health aims to simplify the healthcare experience by connecting patients with family physicians, specialists, and hospitals, facilitating access to major medical treatments. Their team of Loop Coordinators assists patients in finding appropriate doctors, comparing treatment costs, obtaining second opinions, and managing admission procedures, thereby alleviating the stress associated with healthcare decisions. Additionally, Loop Health features a virtual medical practice that supports employees and their families, allowing them to consult with healthcare experts and medical advisors without delay, ultimately promoting better health management and cost-effectiveness.

Scipher Medicine is a biotechnology company based in Waltham, Massachusetts, that focuses on developing a molecular technology platform to predict patient responses to drug therapies, particularly in cardiovascular and autoimmune diseases. The company offers several diagnostic tests, including PrismDx, which identifies patients who may not respond to specific medications, PrismRA for patients with rheumatoid arthritis, and PrismUC for those with ulcerative colitis. These tests enable healthcare providers to prescribe more suitable alternative therapies for patients who are unlikely to benefit from traditional treatments. Scipher Medicine emphasizes the importance of providing scientifically backed data to improve patient outcomes and enhance treatment decisions. The company has also established a strategic partnership with Ambry Genetics Corporation to further advance its capabilities. Founded in 2014, Scipher Medicine was previously known as DZZOM Delaware Corporation before changing its name in 2015.

Viome, Inc. is a biotechnology company based in Bellevue, Washington, that specializes in wellness monitoring through at-home clinical-grade testing kits. Founded in 2016, the company combines analyses of blood, urine, saliva, and stool samples to create detailed profiles of an individual's biochemistry and gut microbiome. Utilizing proprietary RNA sequencing technology, Viome assesses the microbial communities in the digestive system and provides users with personalized insights related to their health. The findings are integrated into a smartphone application that offers tailored recommendations for diet and lifestyle adjustments aimed at preventing and reversing chronic diseases. Viome markets its products through various distributors and online platforms, operating as a subsidiary of BlueDot LLC.

Loop Health is a healthcare provider based in Pune, India, founded in 2018. The company offers a range of services including acute and urgent care, chronic condition management, women's health, health coaching, and preventive care. Loop Health aims to simplify the healthcare experience by connecting patients with family physicians, specialists, and hospitals, facilitating access to major medical treatments. Their team of Loop Coordinators assists patients in finding appropriate doctors, comparing treatment costs, obtaining second opinions, and managing admission procedures, thereby alleviating the stress associated with healthcare decisions. Additionally, Loop Health features a virtual medical practice that supports employees and their families, allowing them to consult with healthcare experts and medical advisors without delay, ultimately promoting better health management and cost-effectiveness.

Known Medicine is looking to take the experimentation of how tumors respond to cancer drugs out of the patient’s body and into the lab. The startup breaks down tumor samples into micro tumors, which they treat separately inside specialized micro-environments with different methods and see what works best.

Even is a health tech company that collaborates with leading hospitals to provide comprehensive healthcare services through a subscription model. Its offerings include unlimited diagnostics, consultations, and hospitalization coverage valued at up to 50 lakh. The company simplifies the reimbursement process by directly transferring funds to partner hospitals, ensuring a seamless experience for members. By charging a recurring monthly fee, Even aims to address critical long-term health needs for individuals, making healthcare more accessible and manageable.

Ellipsis Health, Inc. is a technology company based in San Francisco, California, that specializes in analytics solutions aimed at enhancing behavioral health. Founded in 2013, the company utilizes artificial intelligence to analyze patient speech and clinical data, enabling the prediction of health and well-being. By developing affective computing tools, Ellipsis Health creates real-time behavioral health metrics for patients, allowing health systems to continuously screen for conditions such as depression. This approach provides a simple and cost-effective method for healthcare providers to identify at-risk patients and ensure they receive the necessary support.

Hello Heart is a best in class solution that empowers people to understand and improve their heart health - the #1 cost factor for employers. The program is clinically based and targets people with high blood pressure. Each of our users receives a wireless blood pressure monitor and real-time personalized tips on their smartphone. It is easy to use and helps participants improve their heart health in a fun and engaging way.

Scipher Medicine is a biotechnology company based in Waltham, Massachusetts, that focuses on developing a molecular technology platform to predict patient responses to drug therapies, particularly in cardiovascular and autoimmune diseases. The company offers several diagnostic tests, including PrismDx, which identifies patients who may not respond to specific medications, PrismRA for patients with rheumatoid arthritis, and PrismUC for those with ulcerative colitis. These tests enable healthcare providers to prescribe more suitable alternative therapies for patients who are unlikely to benefit from traditional treatments. Scipher Medicine emphasizes the importance of providing scientifically backed data to improve patient outcomes and enhance treatment decisions. The company has also established a strategic partnership with Ambry Genetics Corporation to further advance its capabilities. Founded in 2014, Scipher Medicine was previously known as DZZOM Delaware Corporation before changing its name in 2015.

Inflammatix, Inc. is a molecular diagnostics company based in Burlingame, California, established in 2016. The company specializes in developing rapid tests that analyze the immune system to address significant clinical and public health challenges, particularly in the diagnosis of acute bacterial and viral infections, as well as sepsis. Utilizing patent-pending biomarkers exclusively licensed from Stanford University, Inflammatix aims to create clinically actionable results through proprietary machine-learning algorithms. In addition to its focus on acute infections and sepsis, the company is expanding its diagnostics pipeline to include tests for tropical infections, autoimmune diseases, transplant rejection, and other medical conditions, ultimately assisting healthcare providers in making informed diagnostic decisions.

AliveCor has a device and application that will turn any smartphone into a clinical-quality electrocardiogram (ECG) recorder. AliveCor is pioneering the creation of FDA-cleared 'machine learning' techniques to enable proactive heart care and is recognized around the world for transforming cardiac care. It specializes in the fields of healthcare, mobile device, and medicine. It was founded in 2010 and headquartered in Mountain View, California.

SiPhox offers a handheld testing device with RNA/DNA and protein testing for point-of-care and At-Home solutions. The company's kit is made by multiplexing RNA, antibody, and antigen tests on a single silicon photonic chip which is amplified by plasmon resonance and silicon photonic resonator readout, enabling users to undertake tests for disease safely and in a disposable point-of-care and at-home manner. SiPhox was founded in 2020 and is based in Cambridge, Massachusetts, USA.

HeartVista is a medical technology company that provides one-click diagnostic imaging. It brought in machine learning to make the scanning process faster, easier, and more consistent. Using AI to control the scanner minimizes the need for breath-holds, making MRI exams available for a broader base of patients and conditions.

Yes Health Inc. is a California-based company that specializes in mobile health solutions, focusing on diabetes prevention and management. Founded in 2015, it offers a comprehensive application that provides personalized nutrition and fitness advice, as well as support from health coaches. The program is designed to engage users actively, making it accessible and effective for individuals looking to adopt healthier lifestyles and prevent the onset of diabetes. Yes Health's team comprises physicians, health coaches, and engineers who work together to create a program that is both affordable and easy to follow. In addition to prevention, the application also aids individuals already diagnosed with diabetes in managing their symptoms effectively, with the overarching mission of promoting lasting health habits and reducing the impact of diabetes.

E25Bio specializes in the development of rapid diagnostic tests for epidemic fever viruses. It is dedicated to preventing severe downstream health outcomes with the use of mobile, fast, real-time reporting to create unprecedented large datasets to guide informed and timely responses for the control of disease spread. The company was founded in 2018 and is headquartered in Cambridge, Massachusetts.

Q Bio provides the first clinically relevant whole body analytics platform. In 60 minutes they analyze medical history, genetics, biochemistry, vitals, and perform a whole body MRI. The platform identifies changes over time associated with the earliest stages of disease before symptoms arise. The company was founded in 2015 and is headquartered in Redwood City, California.

Inflammatix, Inc. is a molecular diagnostics company based in Burlingame, California, established in 2016. The company specializes in developing rapid tests that analyze the immune system to address significant clinical and public health challenges, particularly in the diagnosis of acute bacterial and viral infections, as well as sepsis. Utilizing patent-pending biomarkers exclusively licensed from Stanford University, Inflammatix aims to create clinically actionable results through proprietary machine-learning algorithms. In addition to its focus on acute infections and sepsis, the company is expanding its diagnostics pipeline to include tests for tropical infections, autoimmune diseases, transplant rejection, and other medical conditions, ultimately assisting healthcare providers in making informed diagnostic decisions.

Ellipsis Health, Inc. is a technology company based in San Francisco, California, that specializes in analytics solutions aimed at enhancing behavioral health. Founded in 2013, the company utilizes artificial intelligence to analyze patient speech and clinical data, enabling the prediction of health and well-being. By developing affective computing tools, Ellipsis Health creates real-time behavioral health metrics for patients, allowing health systems to continuously screen for conditions such as depression. This approach provides a simple and cost-effective method for healthcare providers to identify at-risk patients and ensure they receive the necessary support.

Digi-Prex operates a monthly medication delivery platform that focuses on serving patients with chronic diseases in India. Founded in 2019 and headquartered in Hyderabad, with an additional office in San Francisco, the company enables patients to upload prescriptions and receive their medications at discounted rates from local pharmacies. In addition to medication delivery, Digi-Prex offers a comprehensive management solution tailored to individual health needs, providing a one-stop platform for chronic disease management. This approach aims to simplify access to necessary treatments while supporting patients in effectively managing their health conditions.

Hello Heart is a best in class solution that empowers people to understand and improve their heart health - the #1 cost factor for employers. The program is clinically based and targets people with high blood pressure. Each of our users receives a wireless blood pressure monitor and real-time personalized tips on their smartphone. It is easy to use and helps participants improve their heart health in a fun and engaging way.

Probably Genetic is on a mission to help get answers for those with rare genetic conditions that are commonly initially diagnosed as autism spectrum disorder. On average, a patient with a rare genetic condition waits up 7 years to find answers. In the meantime, they spend years bouncing around from doctors to specialists, often at an enormous personal financial cost, to understand if there is more to their, or their child's symptoms. They believe this is too long! Probably Genetic offers educational material and DNA sequencing tests to make it easy to find out if there is more to your symptoms. Their aim is to help those who fall through the cracks of the current healthcare system.

Scipher Medicine is a biotechnology company based in Waltham, Massachusetts, that focuses on developing a molecular technology platform to predict patient responses to drug therapies, particularly in cardiovascular and autoimmune diseases. The company offers several diagnostic tests, including PrismDx, which identifies patients who may not respond to specific medications, PrismRA for patients with rheumatoid arthritis, and PrismUC for those with ulcerative colitis. These tests enable healthcare providers to prescribe more suitable alternative therapies for patients who are unlikely to benefit from traditional treatments. Scipher Medicine emphasizes the importance of providing scientifically backed data to improve patient outcomes and enhance treatment decisions. The company has also established a strategic partnership with Ambry Genetics Corporation to further advance its capabilities. Founded in 2014, Scipher Medicine was previously known as DZZOM Delaware Corporation before changing its name in 2015.

Viome, Inc. is a biotechnology company based in Bellevue, Washington, that specializes in wellness monitoring through at-home clinical-grade testing kits. Founded in 2016, the company combines analyses of blood, urine, saliva, and stool samples to create detailed profiles of an individual's biochemistry and gut microbiome. Utilizing proprietary RNA sequencing technology, Viome assesses the microbial communities in the digestive system and provides users with personalized insights related to their health. The findings are integrated into a smartphone application that offers tailored recommendations for diet and lifestyle adjustments aimed at preventing and reversing chronic diseases. Viome markets its products through various distributors and online platforms, operating as a subsidiary of BlueDot LLC.

Q Bio provides the first clinically relevant whole body analytics platform. In 60 minutes they analyze medical history, genetics, biochemistry, vitals, and perform a whole body MRI. The platform identifies changes over time associated with the earliest stages of disease before symptoms arise. The company was founded in 2015 and is headquartered in Redwood City, California.

DiscernDx provides users with access to individual clinical and molecular data to proactively manage health and make informed decisions. The company offers regular health monitoring, early disease detection, and personalized care for every individual. DiscernDx was founded in 2017 and is based in Palo Alto, California.

Ellipsis Health, Inc. is a technology company based in San Francisco, California, that specializes in analytics solutions aimed at enhancing behavioral health. Founded in 2013, the company utilizes artificial intelligence to analyze patient speech and clinical data, enabling the prediction of health and well-being. By developing affective computing tools, Ellipsis Health creates real-time behavioral health metrics for patients, allowing health systems to continuously screen for conditions such as depression. This approach provides a simple and cost-effective method for healthcare providers to identify at-risk patients and ensure they receive the necessary support.

Totemic makes a device to monitor the health and safety of older adults in a completely passive way--with no wearables required. We are solving the problem of how society will take care of 50m+ older adults in the US in a scalable & humane manner. They can monitor the most salient pieces of information in an older adult's day to day: serious health events like falls, behavioral red flags such as changes in urination frequency, skipping meals, or being bedridden which can all correlate with health decline.

Viome, Inc. is a biotechnology company based in Bellevue, Washington, that specializes in wellness monitoring through at-home clinical-grade testing kits. Founded in 2016, the company combines analyses of blood, urine, saliva, and stool samples to create detailed profiles of an individual's biochemistry and gut microbiome. Utilizing proprietary RNA sequencing technology, Viome assesses the microbial communities in the digestive system and provides users with personalized insights related to their health. The findings are integrated into a smartphone application that offers tailored recommendations for diet and lifestyle adjustments aimed at preventing and reversing chronic diseases. Viome markets its products through various distributors and online platforms, operating as a subsidiary of BlueDot LLC.

MDAlgorithms uses smart algorithms, computer vision, and AI to provide real time mobile tools for people with health disorders. The company's mission is to disrupt the old physician centric medical system and put the patient in the center.

Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

Ontera develops a hand-held point of use diagnostic platform that examines DNA and RNA, and analytes (proteins, viruses, antibodies, etc) from any life form. Use in human and animal diagnostics, agriculture, food safety testing, environmental monitoring, and more. Our platforms use silicon nanopore chips and proprietary biochemistry to accurately detect and differentiate single molecules. We will help transform point-of-care testing and third generation sequencing.

MDacne mission is to disrupt the old physician-centric medical system and put the patient in the center. Using smart algorithms and computer vision to provide real-time mobile tools for people with health disorders. The company's first mobile app, MDacne, targets 500 million people suffering from Acne and provides them an immediate self-diagnosis personalized treatment plan in order to treat their Acne and enhance their quality of life.

Inflammatix, Inc. is a molecular diagnostics company based in Burlingame, California, established in 2016. The company specializes in developing rapid tests that analyze the immune system to address significant clinical and public health challenges, particularly in the diagnosis of acute bacterial and viral infections, as well as sepsis. Utilizing patent-pending biomarkers exclusively licensed from Stanford University, Inflammatix aims to create clinically actionable results through proprietary machine-learning algorithms. In addition to its focus on acute infections and sepsis, the company is expanding its diagnostics pipeline to include tests for tropical infections, autoimmune diseases, transplant rejection, and other medical conditions, ultimately assisting healthcare providers in making informed diagnostic decisions.

Vida Health is a virtual care platform designed from the ground up to treat multiple chronic health conditions simultaneously, through a balance of machine learning that personalizes each person’s treatment and a human connection with real life health coaches and therapists who bring the empathy and accountability people need to reach their goals.

Luminostics, Inc. develops a smartphone-based adaptor to access molecular-level health information through 15-minute DIY disease testing. It serves healthcare professionals and consumers. The company was incorporated in 2015 and is based in Houston, Texas.

Luminist, Inc. is a Newark, California-based company that focuses on developing a diagnostic platform for the early detection of liver disease. Founded in 2015, Luminist aims to provide a rapidly scalable and low-cost solution for screening various diseases, including liver conditions and cancer, through a data-driven approach. The company's technology transforms biochemical data into crucial health information, allowing patients to receive insights from a single test. Luminist operates as a subsidiary of DiscernDx.

Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

CrowdMed, Inc. is a healthcare technology company based in San Francisco, California, established in 2012. It utilizes a prediction market platform to address complex medical issues by tapping into the collective intelligence of a network of medical detectives, which includes licensed physicians, medical students, and other healthcare professionals. This innovative approach allows CrowdMed to provide patients with potential diagnoses and solutions for undiagnosed or chronic symptoms that have eluded traditional medical practices. By combining the insights of numerous contributors, CrowdMed aims to deliver accurate and timely medical suggestions, thereby streamlining the healthcare process. The company seeks to become a trusted resource for millions of patients facing challenging medical conditions.

Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

Vida Health is a virtual care platform designed from the ground up to treat multiple chronic health conditions simultaneously, through a balance of machine learning that personalizes each person’s treatment and a human connection with real life health coaches and therapists who bring the empathy and accountability people need to reach their goals.

Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

CrowdMed, Inc. is a healthcare technology company based in San Francisco, California, established in 2012. It utilizes a prediction market platform to address complex medical issues by tapping into the collective intelligence of a network of medical detectives, which includes licensed physicians, medical students, and other healthcare professionals. This innovative approach allows CrowdMed to provide patients with potential diagnoses and solutions for undiagnosed or chronic symptoms that have eluded traditional medical practices. By combining the insights of numerous contributors, CrowdMed aims to deliver accurate and timely medical suggestions, thereby streamlining the healthcare process. The company seeks to become a trusted resource for millions of patients facing challenging medical conditions.

HealthTap is a healthcare technology company that aims to enhance the accessibility and quality of primary healthcare for patients and doctors. By utilizing a doctor-trained augmented intelligence system, HealthTap connects users with the care they need, facilitating immediate access to medical expertise. The platform is designed for various stakeholders, including employers, insurance companies, and health systems, serving a global audience. With a network of over 100,000 doctors and hundreds of millions of users across 170 countries, HealthTap is committed to providing timely healthcare solutions, improving both patient experiences and operational efficiency in the healthcare sector.

CellScope is a company that specializes in diagnostic imaging solutions by leveraging smartphone technology. Founded in 2010 and based in Menlo Park, California, CellScope has developed a range of devices, including a mobile otoscope and a mobile dermascope, which attach to smartphones to facilitate at-home disease diagnosis. The CellScope Oto transforms a smartphone into a digital otoscope, allowing clinicians to capture and share images and videos securely, enabling effective remote consultations. This technology is particularly beneficial for pediatricians, as it helps create a visual history of conditions like ear infections. By improving remote telemedicine capabilities, CellScope's products enhance patient care, support watchful waiting, and reduce unnecessary antibiotic prescriptions, ultimately saving time and costs for both patients and healthcare providers.

AliveCor has a device and application that will turn any smartphone into a clinical-quality electrocardiogram (ECG) recorder. AliveCor is pioneering the creation of FDA-cleared 'machine learning' techniques to enable proactive heart care and is recognized around the world for transforming cardiac care. It specializes in the fields of healthcare, mobile device, and medicine. It was founded in 2010 and headquartered in Mountain View, California.

HeartVista is a medical technology company that provides one-click diagnostic imaging. It brought in machine learning to make the scanning process faster, easier, and more consistent. Using AI to control the scanner minimizes the need for breath-holds, making MRI exams available for a broader base of patients and conditions.