Matrix Partners is a venture capital firm established in 1977, with offices in San Francisco, Cambridge, Shanghai, Beijing, Mumbai, and Bangalore. The firm focuses on seed, early-stage, late-stage, and growth capital investments across various sectors, including software, communications, artificial intelligence, fintech, digital health, and clean technology. With a commitment to building long-term relationships with entrepreneurs, Matrix Partners aims to support visionary founders in developing significant, industry-leading companies. The firm has a strong track record, having participated in hundreds of investments, with many of its portfolio companies achieving successful IPOs or profitable mergers and acquisitions. The team at Matrix Partners combines local insights with global expertise, comprising both former entrepreneurs and seasoned investors.
Zhangjiagang Onechip Bio-Technology Co.,Ltd. develops and manufactures new generations of biochemical sensor chips and nanomaterials for various applications. It offers pH chip, such as nano-electrodes; biochips; and nanometer materials, including oil absorption and sustained release products and battery protection products. The company’s products are based on the nanoscale electronic biochemical sensors and nanomaterial technologies. It sells its products online. Zhangjiagang Onechip Bio-Technology Co.,Ltd. was founded in 2014 and is based in Zhangjiagang, China.
Shanghai Yudao Biotechnology Co., Ltd. is a biopharmaceutical company established in 2013, headquartered in Shanghai, China. The company specializes in the development of platforms for drug development, alongside offering medical bioinformatics training. Through its innovative approaches, Yudao Bio aims to enhance biopharmaceutical products and contribute to advancements in the healthcare sector.
Ucello Therapeutics focuses on the development of allogeneic cell therapies utilizing its proprietary CAR-T cell technology platform, known as CBT-X20. The company aims to create universal CAR-T cell therapeutic drugs that address unmet clinical needs in cancer treatment. By leveraging advanced gene and cell therapy technologies, Ucello's therapies target cancer cells at the molecular level, making them accessible to patients with varying lymphocyte levels and those with a history of transplant relapse. This innovative approach allows for effective cancer gene therapies to be administered to individuals with specific pre-existing medical conditions.
Starfield Food and Science Technology Limited produces plant-based meat products. It sells its products through outlets and as well as online. The company was founded in 2017 and is based in Shenzhen, China.
Kyinno Biotechnology Co., Ltd. develops anti-tumor drugs and offers customized product development for immuno-oncology and kinase inhibitor discovery. It offers engineered cell lines and antibody products. The company offers services platforms, such as engineered custom cell line development, cell-based assay validation and compound screening, phage display library and hybridoma technology for antibody drug discovery, and cancer cell panel compound profiling and biomarker discovery. Kyinno Biotechnology Co., Ltd. was founded in 2017 and is based in Beijing, China.
Developer of artificial meat. The company develops artificial meat and cultured alternative protein products at the cellular level, committing to creating a new solution for future food supply.
RootPath Genomics, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. The company specializes in developing a personalized T-cell therapy platform that integrates precision medicine with cancer immunotherapy. By focusing on the analysis and manipulation of single immune cells, RootPath aims to enhance the understanding of anti-tumor immunity. Their innovative technologies enable drug developers, physicians, and patients to monitor, modulate, and direct the immune system, facilitating advancements in the diagnosis and treatment of cancer.
Bota Biosciences designs and develops synthetic bioengineering technology platform for bio-manufacturing. The company develops cloud databases and intelligent control software suitable for biotechnology development and production. Bota Biosciences was founded in 2019 and is based in Hangzhou, China.
PAQ Therapeutics is a biotechnology company focused on restoring health and curing diseases by harnessing autophagy, the body's natural process for cellular degradation. The company develops a novel class of small-molecule degraders using autophagosome-tethering compound technology. This innovative approach allows these compounds to bind a diverse array of substrates to the autophagy pathway, enabling healthcare providers to create effective treatments for serious diseases where traditional therapeutic options are often limited. Through its research and development efforts, PAQ Therapeutics aims to provide new solutions for patients in need of advanced medical therapies.
GRIT Biotechnology is engaged in research and development of tumor infiltration lymphocytes immunotherapy for curing solid tumors. The company is based in Shanghai, China.
Developer and manufacturer of diagnostic medical devices and reagents. The company is committed to research and development, manufacture and distribution of its diagnostic medical devices, IVD reagent kits and services, such as rapid test products, latex-enhanced immunoturbidimetry products and autoimmune antibodies.
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.
Qihan Biotech is a biomedical company specializing in genetic technology with a focus on xenotransplantation. The company aims to address the critical shortage of organ donors by utilizing advanced gene editing techniques to develop safe and effective cells, tissues, and organs for human transplantation. Their mission is to eliminate the waiting period associated with organ transplants, providing patients with access to life-saving organs. By harnessing cutting-edge genetic editing technology, Qihan Biotech seeks to create viable organs that can be transplanted into humans, thereby contributing to a solution for the global organ donor crisis.
Senti Biosciences is a clinical-stage biotechnology company based in South San Francisco, California, focused on developing innovative gene and cell therapies using its proprietary synthetic biology platform. Founded in 2016, the company aims to address complex diseases through advanced therapeutic solutions. Senti's technology includes engineered allogeneic chimeric antigen receptor natural killer (CAR-NK) cells, which are designed to target and eliminate cancer cells while minimizing damage to healthy tissue. Among its product candidates are SENTI-202, a Logic Gated CAR-NK cell therapy intended for cancer treatment, and SENTI-301A, which targets hepatocellular carcinoma. Senti Biosciences operates as a resident company at Johnson & Johnson Innovation's JLABS in South San Francisco, collaborating with experts in synthetic biology and computation to advance its therapeutic developments.
Developer of artificial meat. The company develops artificial meat and cultured alternative protein products at the cellular level, committing to creating a new solution for future food supply.
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.
NUANCE BIOTECH INC operates as a pharmaceutical development company. The company provides capsules, injections, and tubes. It also engages in research and development for drug development, commercial and academic platform for pharmaceuticals, and contract sales organization services. The company was founded in 2014 and is based in Shanghai, China.
GRIT Biotechnology is engaged in research and development of tumor infiltration lymphocytes immunotherapy for curing solid tumors. The company is based in Shanghai, China.
D3 Bio Inc. is a biotechnology company founded in 2020 and based in China. It specializes in the development and registration of innovative medicines, primarily focusing on oncology and immunology. The company adopts a unique approach to medicine development by first identifying significant unmet patient and market needs, particularly in areas where current treatments are inadequate. This understanding informs their research and guides the selection of appropriate scientific and technological methods to define their drug development strategy. Through this differentiated approach, D3 Bio aims to address critical health challenges and improve clinical outcomes for patients.
Starfield Food and Science Technology Limited produces plant-based meat products. It sells its products through outlets and as well as online. The company was founded in 2017 and is based in Shenzhen, China.
GeneCast Biotechnology Co., Ltd. is a Beijing-based company founded in 2014 that specializes in gene research and the development of advanced cancer diagnostic solutions. The company offers a technology platform for cell-free DNA next-generation sequencing (NGS) tests, which are used for companion diagnostics, genetic profiling, prognosis, and monitoring of various solid tumors, including lung, colorectal, liver, and breast cancers. GeneCast provides non-invasive and precise tumor diagnoses and personalized treatment guidance, leveraging high-throughput sequencing and bioinformatics. The company collaborates with hospitals and research institutions to enhance cancer treatment and genetic testing, aiming to improve patient outcomes and quality of life. GeneCast is also focused on advancing its research and clinical trials while expanding its distribution channels.
Beijing Advaccine Biotechnology Co., Ltd. is a biotechnology company dedicated to the discovery and development of innovative vaccines, both preventive and therapeutic. The company's product pipeline includes vaccines targeting respiratory syncytial virus (RSV), hepatitis B virus (HBV), and a therapeutic vaccine for type 1 diabetes (T1D). Advaccine's research focuses on addressing unmet clinical needs globally, with an emphasis on first-in-class products. The company aims to enhance patient care by inducing immuno-tolerance and stimulating T-cell responses for specific diseases. Based in Beijing, China, Advaccine is committed to advancing viral vaccine technology to improve health outcomes.
InventisBio Inc. is a biotechnology company focused on discovering and developing innovative therapeutics for cancer and metabolic diseases. Founded in 2013 and based in Pudong, China, the company is advancing a pipeline of small molecule drug candidates targeting lung cancer, breast cancer, and gout. Notably, it is developing D-0316, a third-generation EGFR-T790M tyrosine kinase inhibitor, and is exploring combinations of its drugs with other immuno-oncology therapies, such as PD-1 antibodies, for various cancer indications. Co-founded by Dr. Yaolin Wang and a team of scientists with prior experience at major pharmaceutical companies like Merck and Schering-Plough, InventisBio aims to leverage their expertise in oncology and metabolic diseases to bring effective treatments to market.
Bota Biosciences designs and develops synthetic bioengineering technology platform for bio-manufacturing. The company develops cloud databases and intelligent control software suitable for biotechnology development and production. Bota Biosciences was founded in 2019 and is based in Hangzhou, China.
Bota Biosciences designs and develops synthetic bioengineering technology platform for bio-manufacturing. The company develops cloud databases and intelligent control software suitable for biotechnology development and production. Bota Biosciences was founded in 2019 and is based in Hangzhou, China.
Bota Biosciences designs and develops synthetic bioengineering technology platform for bio-manufacturing. The company develops cloud databases and intelligent control software suitable for biotechnology development and production. Bota Biosciences was founded in 2019 and is based in Hangzhou, China.
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.
Starfield Food and Science Technology Limited produces plant-based meat products. It sells its products through outlets and as well as online. The company was founded in 2017 and is based in Shenzhen, China.
Rgenta Therapeutics develops a pipeline of oral, small-molecule RNA-targeting medicines with an initial focus on oncology. Its proprietary platform mines the massive genomics data to identify targetable RNA processing events and design small-molecule glue to modulate the interactions among the spliceosome, regulatory proteins, and RNAs. Its lead programs and unique approach are unlocking the therapeutic potential of historically undruggable targets in human diseases.
It was founded in 2018 and is headquartered in Cambridge, Massachusetts.
Starfield Food and Science Technology Limited produces plant-based meat products. It sells its products through outlets and as well as online. The company was founded in 2017 and is based in Shenzhen, China.
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.
RootPath Genomics, Inc. is a biotechnology company based in Cambridge, Massachusetts, founded in 2017. The company specializes in developing a personalized T-cell therapy platform that integrates precision medicine with cancer immunotherapy. By focusing on the analysis and manipulation of single immune cells, RootPath aims to enhance the understanding of anti-tumor immunity. Their innovative technologies enable drug developers, physicians, and patients to monitor, modulate, and direct the immune system, facilitating advancements in the diagnosis and treatment of cancer.
Lansion Biotechnology is specialized in research & development, production, sell, services of in vitro diagnostic reagents and devices. With its advanced technology concept, Lansionbio provides equioment, reagents and services to world-wild clients according to their needs.
GeneCast Biotechnology Co., Ltd. is a Beijing-based company founded in 2014 that specializes in gene research and the development of advanced cancer diagnostic solutions. The company offers a technology platform for cell-free DNA next-generation sequencing (NGS) tests, which are used for companion diagnostics, genetic profiling, prognosis, and monitoring of various solid tumors, including lung, colorectal, liver, and breast cancers. GeneCast provides non-invasive and precise tumor diagnoses and personalized treatment guidance, leveraging high-throughput sequencing and bioinformatics. The company collaborates with hospitals and research institutions to enhance cancer treatment and genetic testing, aiming to improve patient outcomes and quality of life. GeneCast is also focused on advancing its research and clinical trials while expanding its distribution channels.
Ansun BioPharma is a clinical-stage biopharmaceutical company focused on the development of unique host-directed anti-viral. The company is committed to developing safe and effective immuno-biologic therapies to treat the most vulnerable patients. Its founders were ingenious virologists and molecular biologists who realized that targeting a virus is difficult due to the virus’s ability to mutate and avoid the treatment. This ability to mutate also enables the virus to evade vaccines. So instead of trying to hit a moving target, they developed an innovative new approach to fight respiratory viruses: they targeted the host instead of the virus.
The company was founded in 2003 and is headquartered in San Diego, California.
Shenzhen Tiantian Xuenong Network Technology Co., Ltd. operates an agricultural technology knowledge learning platform in China, established in 2017 and headquartered in Shenzhen. The platform offers a range of agricultural technical knowledge courses aimed at enhancing the skills of farmers. These courses cover essential topics such as variety selection, cultivation management, pest control, nutrient fertilization, and harvesting. Tiantianxuenong serves farmers through various formats, including curriculum teaching, expert consultation, online and offline training, and public welfare activities. By providing valuable educational resources, the company aims to improve farming practices and management capabilities, thereby supporting the agricultural community in multiple dimensions.
Chameleon Biosciences Inc. specializes in developing gene therapy solutions using Adeno Associated Virus (AAV) technology to address rare genetic diseases. Founded in 2017 and based in San Anselmo, California, the company focuses on delivering therapeutic proteins to targeted tissues while minimizing immune responses to enhance gene delivery and reduce immunogenicity. Chameleon aims to transform the treatment landscape for genetic disorders, particularly in infants, where a significant percentage of fatalities are attributed to these conditions. The company is dedicated to ensuring that affected children receive accurate, lower-dose treatments that can be administered multiple times as needed. By masking foreign proteins and shielding the viral capsid from antibodies, Chameleon seeks to increase the range of diseases that can be treated effectively, thereby improving patient outcomes and quality of life.
Shenzhen Tiantian Xuenong Network Technology Co., Ltd. operates an agricultural technology knowledge learning platform in China, established in 2017 and headquartered in Shenzhen. The platform offers a range of agricultural technical knowledge courses aimed at enhancing the skills of farmers. These courses cover essential topics such as variety selection, cultivation management, pest control, nutrient fertilization, and harvesting. Tiantianxuenong serves farmers through various formats, including curriculum teaching, expert consultation, online and offline training, and public welfare activities. By providing valuable educational resources, the company aims to improve farming practices and management capabilities, thereby supporting the agricultural community in multiple dimensions.
Beijing Chemclin Biotech Co., Ltd. specializes in the development, production, and sales of diagnostic reagents and instruments for clinical use. Founded in 1999 and based in Beijing, China, the company focuses on in-vitro diagnostics, offering a range of products including reagents for infectious diseases, tumor markers, and thyroid and diabetes testing. Chemclin also provides semi-automated and fully automated chemiluminescent analyzers, which facilitate the performance of chemiluminescent assays. Additionally, the company offers commercial testing services for various health conditions, including liver fibrosis and fertility. As a subsidiary of China Diagnostics Medical Corporation, Chemclin is committed to delivering innovative diagnostic solutions and services to the Chinese healthcare market.
SA Biotech
Series B in 2018
SA Biotech is a Healthcare company.
Si'ao Biotechnology
Series A in 2018
Si'ao Biotechnology engages in the development and production of genetic engineering vaccines and test kits.
Grandomics Biosciences Co., Ltd. is a precision medical company based in Beijing, China, specializing in genetic sequencing and diagnosis. Founded in 2014, Grandomics offers a range of solutions for monogenic diseases, including Whole Exome Sequencing (WES), Whole Genome Sequencing (WGS), and multiplex ligation-dependent probe amplification. The company also focuses on specific disorders such as facioscapulohumeral muscular dystrophy. In addition to these diagnostic services, Grandomics provides advanced sequencing platforms like Oxford Nanopore and Pacbio Sequel, along with GrandBox™, a software suite for clinical sample management and data analysis. This integrated approach enables comprehensive genetic testing and carrier screening, positioning Grandomics as a key player in the field of molecular diagnosis and genetic research.
Adlai Nortye Biopharma Co., Ltd. is a biopharmaceutical company based in Hangzhou, China, focused on the research and development of innovative treatments for cancer and metabolic diseases. Founded in 2004 and formerly known as Sinopep Pharmaceutical Inc., the company has shifted its emphasis to oncology and immuno-oncology. Adlai Nortye is committed to improving patient outcomes through the discovery and commercialization of differentiated medicines. With a solid foundation in peptide and protein drug development, the company has broadened its scope to include small molecules and therapeutic antibodies. It holds 23 granted patents and has published 7 PCT applications. Through strategic collaborations with global partners, Adlai Nortye has established a diverse pipeline of programs ranging from early pre-clinical stages to those ready for phase 3 clinical trials.
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.
Ansun BioPharma is a clinical-stage biopharmaceutical company focused on the development of unique host-directed anti-viral. The company is committed to developing safe and effective immuno-biologic therapies to treat the most vulnerable patients. Its founders were ingenious virologists and molecular biologists who realized that targeting a virus is difficult due to the virus’s ability to mutate and avoid the treatment. This ability to mutate also enables the virus to evade vaccines. So instead of trying to hit a moving target, they developed an innovative new approach to fight respiratory viruses: they targeted the host instead of the virus.
The company was founded in 2003 and is headquartered in San Diego, California.
Shenzhen Tiantian Xuenong Network Technology Co., Ltd. operates an agricultural technology knowledge learning platform in China, established in 2017 and headquartered in Shenzhen. The platform offers a range of agricultural technical knowledge courses aimed at enhancing the skills of farmers. These courses cover essential topics such as variety selection, cultivation management, pest control, nutrient fertilization, and harvesting. Tiantianxuenong serves farmers through various formats, including curriculum teaching, expert consultation, online and offline training, and public welfare activities. By providing valuable educational resources, the company aims to improve farming practices and management capabilities, thereby supporting the agricultural community in multiple dimensions.
Chengdu 23Mofang Biotechnology Co., Ltd. specializes in genetic testing services, primarily focusing on saliva-based testing. Founded in 2015 and based in Chengdu, China, the company provides insights into ancestral origins, genetic risks, and traits by analyzing samples and delivering detailed reports through a mobile application. 23Mofang aims to leverage the Internet and genetic testing to create a comprehensive life data database, with a mission to enhance individual well-being through accessible genetic information. The company positions itself as a reliable technology enterprise that benefits society by enabling users and their families to proactively address potential health issues.
GeneCast Biotechnology Co., Ltd. is a Beijing-based company founded in 2014 that specializes in gene research and the development of advanced cancer diagnostic solutions. The company offers a technology platform for cell-free DNA next-generation sequencing (NGS) tests, which are used for companion diagnostics, genetic profiling, prognosis, and monitoring of various solid tumors, including lung, colorectal, liver, and breast cancers. GeneCast provides non-invasive and precise tumor diagnoses and personalized treatment guidance, leveraging high-throughput sequencing and bioinformatics. The company collaborates with hospitals and research institutions to enhance cancer treatment and genetic testing, aiming to improve patient outcomes and quality of life. GeneCast is also focused on advancing its research and clinical trials while expanding its distribution channels.
Qrativ is a developer of a drug purposing platform designed to reinvent the way treatments for diseases with unmet medical need are discovered and developed. The company's platform ,Darwin.ai, identifies new uses for existing molecules for diseases with unmet medical need and uses machine learning and artificial intelligence for research and development, enabling patient to get treatments for diseases for which drugs are not available in the market.
NUANCE BIOTECH INC operates as a pharmaceutical development company. The company provides capsules, injections, and tubes. It also engages in research and development for drug development, commercial and academic platform for pharmaceuticals, and contract sales organization services. The company was founded in 2014 and is based in Shanghai, China.
TopGene is a genomics technology company based in Guangzhou, China, founded in 2014. It specializes in genetic testing, molecular diagnostics, and companion diagnostics for various diseases, including chromosomal disorders, hereditary deafness, newborn genetic metabolic diseases, and cancers. The company provides a range of next-generation sequencing and DNA/RNA extraction services to academic, biotechnology, government, and pharmaceutical sectors. Its offerings include applications such as exome sequencing, transcriptome sequencing, and whole genome sequencing. TopGene focuses on patient-centered care and aims to enhance human health through an integrated service model that combines scientific research with clinical applications. By promoting precision medicine, TopGene contributes to advancements in the fields of genetics and cellular technology.
Grandomics Biosciences Co., Ltd. is a precision medical company based in Beijing, China, specializing in genetic sequencing and diagnosis. Founded in 2014, Grandomics offers a range of solutions for monogenic diseases, including Whole Exome Sequencing (WES), Whole Genome Sequencing (WGS), and multiplex ligation-dependent probe amplification. The company also focuses on specific disorders such as facioscapulohumeral muscular dystrophy. In addition to these diagnostic services, Grandomics provides advanced sequencing platforms like Oxford Nanopore and Pacbio Sequel, along with GrandBox™, a software suite for clinical sample management and data analysis. This integrated approach enables comprehensive genetic testing and carrier screening, positioning Grandomics as a key player in the field of molecular diagnosis and genetic research.
nference, Inc. operates an AI-based software platform that integrates and synthesizes biomedical knowledge from both unstructured and structured data sources, including scientific literature and real-world datasets. The platform utilizes advanced neural networks to automate the extraction of insights, facilitating real-time analysis for various applications within the life sciences sector, including drug discovery, development, and precision medicine. By addressing critical healthcare challenges, nference aims to enhance research and development efforts, as well as inform commercial strategies. Founded in 2013 and originally known as Lumen Biomics, nference is headquartered in Cambridge, Massachusetts, with additional offices in Bengaluru, India; Toronto, Canada; and Rochester, Minnesota.
GeneDock, founded in September 2014, is a national high-tech enterprise specializing in precision medical data technology. The company develops and provides a comprehensive SaaS platform that allows users to extract, analyze, and visualize medical records, facilitating improved research and studies for medical and scientific institutions. With industry-leading expertise, GeneDock has successfully built data platforms for numerous prominent facilities, including top three hospitals and leading industry organizations in China. The core team comprises members with backgrounds from renowned companies, and the firm has attracted investment from notable institutions. GeneDock aims to drive innovation in healthcare through advanced data technology solutions.
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