New Enterprise Associates

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an investigational therapy. The company's lead product, Haduvio, is an oral extended-release formulation of nalbuphine currently undergoing Phase IIb/III clinical trials. Trevi Therapeutics is focused on addressing serious neurologically mediated conditions, including chronic pruritus, chronic cough associated with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in Parkinson's disease patients. The ongoing PRISM trial evaluates Haduvio's effectiveness in treating severe pruritus related to prurigo nodularis, highlighting its potential in managing conditions linked by a common pathophysiology involving opioid receptors in the nervous system. Founded in 2011, Trevi Therapeutics aims to provide innovative therapeutic solutions for patients with significant unmet medical needs.

Plaid Inc. is a technology platform that enables users to connect their bank accounts to various financial applications, facilitating a more modern and digitally-enabled financial system. Founded in 2012 and headquartered in San Francisco, the company offers a suite of APIs that allows developers to create innovative financial products. Its offerings include tools for accessing transaction histories, authenticating bank accounts, verifying user identities, confirming real-time account balances, and assessing borrowers' assets and income. Plaid's solutions cater to a wide range of financial activities, including personal finances, consumer payments, lending, and business transactions. The platform serves a diverse clientele, including Fortune 50 companies, and aims to democratize financial services by providing the necessary infrastructure for both small startups and large financial institutions to enhance their service offerings.

New Wave Foods, Inc. specializes in producing and selling plant-based seafood products, focusing primarily on sustainable shrimp alternatives. Founded in 2015 and headquartered in San Francisco, California, the company offers a variety of items, including sautéed, grilled, breaded, and fried shrimp, as well as shrimp tacos and salads. Its products are made from sustainably sourced seaweed and soy protein, enriched with natural flavors and essential amino acids, providing a healthy, low-calorie, and zero-cholesterol option for consumers. Targeting the culinary market in the United States, New Wave Foods aims to preserve and enrich seafood traditions through its innovative plant-based offerings.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an investigational therapy. The company's lead product, Haduvio, is an oral extended-release formulation of nalbuphine currently undergoing Phase IIb/III clinical trials. Trevi Therapeutics is focused on addressing serious neurologically mediated conditions, including chronic pruritus, chronic cough associated with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in Parkinson's disease patients. The ongoing PRISM trial evaluates Haduvio's effectiveness in treating severe pruritus related to prurigo nodularis, highlighting its potential in managing conditions linked by a common pathophysiology involving opioid receptors in the nervous system. Founded in 2011, Trevi Therapeutics aims to provide innovative therapeutic solutions for patients with significant unmet medical needs.

Plaid Inc. is a technology platform that enables users to connect their bank accounts to various financial applications, facilitating a more modern and digitally-enabled financial system. Founded in 2012 and headquartered in San Francisco, the company offers a suite of APIs that allows developers to create innovative financial products. Its offerings include tools for accessing transaction histories, authenticating bank accounts, verifying user identities, confirming real-time account balances, and assessing borrowers' assets and income. Plaid's solutions cater to a wide range of financial activities, including personal finances, consumer payments, lending, and business transactions. The platform serves a diverse clientele, including Fortune 50 companies, and aims to democratize financial services by providing the necessary infrastructure for both small startups and large financial institutions to enhance their service offerings.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an investigational therapy. The company's lead product, Haduvio, is an oral extended-release formulation of nalbuphine currently undergoing Phase IIb/III clinical trials. Trevi Therapeutics is focused on addressing serious neurologically mediated conditions, including chronic pruritus, chronic cough associated with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in Parkinson's disease patients. The ongoing PRISM trial evaluates Haduvio's effectiveness in treating severe pruritus related to prurigo nodularis, highlighting its potential in managing conditions linked by a common pathophysiology involving opioid receptors in the nervous system. Founded in 2011, Trevi Therapeutics aims to provide innovative therapeutic solutions for patients with significant unmet medical needs.

Trevi Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in New Haven, Connecticut, dedicated to developing and commercializing nalbuphine ER, an investigational therapy. The company's lead product, Haduvio, is an oral extended-release formulation of nalbuphine currently undergoing Phase IIb/III clinical trials. Trevi Therapeutics is focused on addressing serious neurologically mediated conditions, including chronic pruritus, chronic cough associated with idiopathic pulmonary fibrosis, and levodopa-induced dyskinesia in Parkinson's disease patients. The ongoing PRISM trial evaluates Haduvio's effectiveness in treating severe pruritus related to prurigo nodularis, highlighting its potential in managing conditions linked by a common pathophysiology involving opioid receptors in the nervous system. Founded in 2011, Trevi Therapeutics aims to provide innovative therapeutic solutions for patients with significant unmet medical needs.

Plaid Inc. is a technology platform that enables users to connect their bank accounts to various financial applications, facilitating a more modern and digitally-enabled financial system. Founded in 2012 and headquartered in San Francisco, the company offers a suite of APIs that allows developers to create innovative financial products. Its offerings include tools for accessing transaction histories, authenticating bank accounts, verifying user identities, confirming real-time account balances, and assessing borrowers' assets and income. Plaid's solutions cater to a wide range of financial activities, including personal finances, consumer payments, lending, and business transactions. The platform serves a diverse clientele, including Fortune 50 companies, and aims to democratize financial services by providing the necessary infrastructure for both small startups and large financial institutions to enhance their service offerings.

Spine Wave, Inc. manufactures and markets medical equipment for the treatment of spinal disorders. It offers expandable PEEK spacers and expandable interbody devices for posterior surgery; pivoting spacer systems; lateral spacer systems, XDL expandable devices, and lateral access systems for lateral stabilization; Leva PX, an expandable interbody device for the treatment of spinal disorders; GraftMag Graft Delivery System to deliver large amounts of bone graft; and fixation products, such as spine systems for treating degeneration, deformity, tumor, and trauma of the thoracolumbar spine, as well as adjacent level systems. The company also offers anterior cervical plate systems that provide stabilization as an adjunct to spinal fusion from C2-C7 through anterior screw fixation; and cervical spacer systems to treat degenerative disc disease from C2-T1. It offers its products through distributors. Spine Wave, Inc. was founded in 2001 and is based in Shelton, Connecticut.

Plaid Inc. is a technology platform that enables users to connect their bank accounts to various financial applications, facilitating a more modern and digitally-enabled financial system. Founded in 2012 and headquartered in San Francisco, the company offers a suite of APIs that allows developers to create innovative financial products. Its offerings include tools for accessing transaction histories, authenticating bank accounts, verifying user identities, confirming real-time account balances, and assessing borrowers' assets and income. Plaid's solutions cater to a wide range of financial activities, including personal finances, consumer payments, lending, and business transactions. The platform serves a diverse clientele, including Fortune 50 companies, and aims to democratize financial services by providing the necessary infrastructure for both small startups and large financial institutions to enhance their service offerings.

Loxo Oncology, Inc., a biopharmaceutical company, develops and sells medicines for patients with genetically defined cancers in the United States. Its lead product candidate comprises larotrectinib, an oral selective inhibitor of tropomyosin receptor kinase (TRK), which is in adult Phase 1 trial, a pediatric Phase 1/2 trial, and an adult/adolescent Phase 2 trial for the treatment of patients with tumor types, such as lung, head and neck, melanoma, colorectal, sarcoma, and breast cancer. The company’s preclinical programs include LOXO-195, a drug candidate in preclinical development to address predicted acquired resistance mechanisms; RET inhibitor that optimizes potency for rearranged during transfection (RET) fusion proteins, mutations, and anticipated mechanisms of acquired resistance; and FGFR inhibitor that enables potently inhibiting FGFR isoforms comprising four isoforms with tyrosine kinase domains. It has a drug discovery collaboration agreement with Array BioPharma, Inc.; strategic partnership agreement with Illumina, Inc.; research collaboration agreement with Veracyte, Inc.; and strategic partnership agreement with Amoy Diagnostics Co., Ltd. and PREMIA Holdings (HK) Ltd. Loxo Oncology, Inc. was founded in 2013 and is headquartered in Stamford, Connecticut. Loxo Oncology, Inc. is a subsidiary of Eli Lilly and Company.

Plaid Inc. is a technology platform that enables users to connect their bank accounts to various financial applications, facilitating a more modern and digitally-enabled financial system. Founded in 2012 and headquartered in San Francisco, the company offers a suite of APIs that allows developers to create innovative financial products. Its offerings include tools for accessing transaction histories, authenticating bank accounts, verifying user identities, confirming real-time account balances, and assessing borrowers' assets and income. Plaid's solutions cater to a wide range of financial activities, including personal finances, consumer payments, lending, and business transactions. The platform serves a diverse clientele, including Fortune 50 companies, and aims to democratize financial services by providing the necessary infrastructure for both small startups and large financial institutions to enhance their service offerings.

Spine Wave, Inc. manufactures and markets medical equipment for the treatment of spinal disorders. It offers expandable PEEK spacers and expandable interbody devices for posterior surgery; pivoting spacer systems; lateral spacer systems, XDL expandable devices, and lateral access systems for lateral stabilization; Leva PX, an expandable interbody device for the treatment of spinal disorders; GraftMag Graft Delivery System to deliver large amounts of bone graft; and fixation products, such as spine systems for treating degeneration, deformity, tumor, and trauma of the thoracolumbar spine, as well as adjacent level systems. The company also offers anterior cervical plate systems that provide stabilization as an adjunct to spinal fusion from C2-C7 through anterior screw fixation; and cervical spacer systems to treat degenerative disc disease from C2-T1. It offers its products through distributors. Spine Wave, Inc. was founded in 2001 and is based in Shelton, Connecticut.

Spine Wave, Inc. manufactures and markets medical equipment for the treatment of spinal disorders. It offers expandable PEEK spacers and expandable interbody devices for posterior surgery; pivoting spacer systems; lateral spacer systems, XDL expandable devices, and lateral access systems for lateral stabilization; Leva PX, an expandable interbody device for the treatment of spinal disorders; GraftMag Graft Delivery System to deliver large amounts of bone graft; and fixation products, such as spine systems for treating degeneration, deformity, tumor, and trauma of the thoracolumbar spine, as well as adjacent level systems. The company also offers anterior cervical plate systems that provide stabilization as an adjunct to spinal fusion from C2-C7 through anterior screw fixation; and cervical spacer systems to treat degenerative disc disease from C2-T1. It offers its products through distributors. Spine Wave, Inc. was founded in 2001 and is based in Shelton, Connecticut.

Spine Wave, Inc. manufactures and markets medical equipment for the treatment of spinal disorders. It offers expandable PEEK spacers and expandable interbody devices for posterior surgery; pivoting spacer systems; lateral spacer systems, XDL expandable devices, and lateral access systems for lateral stabilization; Leva PX, an expandable interbody device for the treatment of spinal disorders; GraftMag Graft Delivery System to deliver large amounts of bone graft; and fixation products, such as spine systems for treating degeneration, deformity, tumor, and trauma of the thoracolumbar spine, as well as adjacent level systems. The company also offers anterior cervical plate systems that provide stabilization as an adjunct to spinal fusion from C2-C7 through anterior screw fixation; and cervical spacer systems to treat degenerative disc disease from C2-T1. It offers its products through distributors. Spine Wave, Inc. was founded in 2001 and is based in Shelton, Connecticut.

Mission Critical Software provides systems administration and operations management software productsvfor corporate and Internet-based Windows NT networks. Their OnePoint productvsuite is designed to improve the reliability, performance and security of even the largest and most complex computing environments by simplifying andvautomating key systems management functions.

Mission Critical Software provides systems administration and operations management software productsvfor corporate and Internet-based Windows NT networks. Their OnePoint productvsuite is designed to improve the reliability, performance and security of even the largest and most complex computing environments by simplifying andvautomating key systems management functions.