OrbiMed

OrbiMed Advisors LLC is a healthcare-focused investment firm founded in 1989, managing approximately $5 billion in assets. The firm specializes in a range of investment strategies, including private equity, venture capital, and public equity, targeting companies across the healthcare spectrum—from startups to large multinational corporations. OrbiMed invests in various sectors within the healthcare industry, including pharmaceuticals, biotechnology, life sciences, medical devices, and health IT. The firm typically invests between $3 million and $150 million, often seeking majority stakes in its portfolio companies. With a global investment approach, OrbiMed operates from offices in New York, San Francisco, Mumbai, Herzliya, Shanghai, West Kowloon, and Luxembourg, focusing on opportunities in North America, Europe, Asia, and Israel. Its investment strategies are underpinned by fundamental analysis, encompassing investments in public equity, fixed income, and alternative markets.
601 Lexington Avenue (at 53rd Street), 54th Floor New York, NY 10022-4629
1700 Owens Street Suite 540 San Francisco, CA 94158
Suite F 27, Grand Hyatt Plaza Santacruz (East) Mumbai, 400055, India
89 Medinat HaYehudim St Building E, 11th Floor Herzliya 4614001, Israel
Unit 4706, Raffles City Shanghai Office Tower 268 Xizang Middle Road Shanghai 200001, P.R. China
12/F International Commerce Centre 1 Austin Road West, Unit 01 Kowloon, Hong Kong

Roy Amariglio

Principal

Mona Ashiya

Partner

David Bonita

General Partner

Sven H. Borho

Managing Partner

Vince Burgess

Venture Partner

Evan Caplan

Principal

Erez Chimovits

Partner, Private Equity

Nissim Darvish

Senior Managing Director

Ronny Ginor

Venture Partner

Carl L. Gordon

Managing Partner

Rishi Gupta

Partner

Geoffrey Hsu

General Partner

Samuel D. Isaly

Managing Partner

Mark Jelley

Partner

Chau Khuong

Partner

Kevin Koch

Venture Partner

Anat Naschitz

Managing Director

Carter Neild

Managing Partner

Trevor Polischuk

Partner

Matthew Rizzo

General Partner

William F. Sawyer

Partner

Sunny Sharma

Partner

Michael B. Sheffery

Partner & Co-Founder

Jonathan Silverstein

Partner

Stephen Squinto Ph.D

Partner

C. Scotland Stevens

General Partner

Kerrie Swingle

Director of Investor Services

David G. Wang

Partner

Steven D. Wang

Partner

Jonathan Wang Ph.D

Senior Managing Director

Tal Zaks

Partner

Past deals in Health Diagnostics

Adaptive Biotechnologies is a commercial-stage company focused on advancing immune-driven medicine by leveraging the biology of the adaptive immune system for disease diagnosis and treatment. Founded in 2009 and headquartered in Seattle, Washington, the company offers a range of products and services, including the immunoSEQ research service and kit, which aids in research and the discovery of diagnostic signals. Its FDA-authorized clonoSEQ diagnostic test is designed for the detection and monitoring of minimal residual disease in patients with specific blood cancers. Additionally, Adaptive Biotechnologies is developing a pipeline of clinical products aimed at diagnosing and treating cancer, autoimmune conditions, and infectious diseases. The company has formed strategic collaborations with notable partners, including Genentech for neoantigen-directed T cell therapies, Microsoft for early disease detection tests from blood samples, and Amgen for therapeutic development related to COVID-19.

Delfi Diagnostics

Series B in 2022
Delfi Diagnostics, Inc. is a biotechnology company based in Baltimore, Maryland, that specializes in early cancer detection through non-invasive blood tests. Founded in 2018, the company utilizes advanced artificial intelligence and genome sequencing technologies to identify unique patterns of DNA fragmentation in patients' blood, enabling the detection of cancer at its most treatable stage. By focusing on precision diagnostics, Delfi Diagnostics aims to improve patient outcomes and contribute to the evolving landscape of cancer care.

DarioHealth

Post in 2022
DarioHealth Corp. is a digital health company focused on developing and commercializing proprietary technologies that enable consumers to conduct laboratory testing using smartphones and mobile devices. Its primary product, the Dario Smart Diabetes Management Solution, integrates a mobile application with a pocket-sized blood glucose monitoring device. This real-time, cloud-based solution assists users in managing their diabetes by offering features such as monitoring of chronic conditions, coaching, digital communication, and real-time alerts for trends and patterns. DarioHealth markets its products through direct consumer sales, retail pharmacies, hospitals, distributors, and online platforms. The company, originally known as LabStyle Innovations Corp., was founded in 2011 and is headquartered in Caesarea, Israel.

Nucleix

Venture Round in 2022
Nucleix develops, manufactures, and markets non-invasive molecular cancer diagnostic tests. Its sensitive and specific tests are based on identification of subtle changes in methylation patterns. Nucleix offers a urine test for monitoring of bladder cancer called Bladder EpiCheck and a blood test for early detection of lung cancer called Lung EpiCheck. Adam Wasserstrom, Danny Frumkin, and Elon Ganor founded it in 2008, with its headquarters in Rehovot in Israel.

PierianDx

Venture Round in 2021
PierianDx, Inc. is a technology company that develops a genomic software-as-a-service (SaaS) solution designed to manage, analyze, and interpret complex genomic tests for clinical laboratories in the United States. The company offers the Clinical Genomicist Workstation, a platform that streamlines the workflow for patient cases, handling everything from sequencing and analysis to report generation and integration with electronic health records. PierianDx aims to enhance the adoption of genomic sequencing in healthcare, enabling physicians to diagnose and treat patients with cancer and other complex diseases more effectively. The company also provides consulting and technical services to support its clients, which include health systems, children's hospitals, comprehensive cancer centers, and reference laboratories. Founded in 2014 and headquartered in Saint Louis, Missouri, PierianDx has established itself as a trusted source for advanced genomic reporting and decision support in clinical care.

Adela

Series A in 2021
Adela is focused on the detection of cancer and other high-morbidity, high-mortality conditions through a routine blood test.

Binx Health

Series E in 2021
Binx Health Limited is an in vitro diagnostics company based in Trowbridge, United Kingdom, specializing in the development of diagnostic instruments and disposable cartridge systems for decentralized laboratory and point-of-care environments. The company's flagship products include the io System, which detects infectious diseases such as chlamydia and MRSA, and Callisto, designed to accommodate various testing throughput requirements. Binx Health focuses on providing solutions for sexually transmitted infections and hospital-acquired infections. The company aims to enhance healthcare accessibility by delivering on-demand testing directly to consumers, utilizing its proprietary, desktop, PCR-based platforms and mobile offerings. Established in 2005, Binx Health has formed a strategic partnership with Sherlock Biosciences to further advance its innovative healthcare solutions.

Nucleix

Venture Round in 2021
Nucleix develops, manufactures, and markets non-invasive molecular cancer diagnostic tests. Its sensitive and specific tests are based on identification of subtle changes in methylation patterns. Nucleix offers a urine test for monitoring of bladder cancer called Bladder EpiCheck and a blood test for early detection of lung cancer called Lung EpiCheck. Adam Wasserstrom, Danny Frumkin, and Elon Ganor founded it in 2008, with its headquarters in Rehovot in Israel.

Crossover Health

Series D in 2021
Crossover Health, Inc. specializes in workplace healthcare services aimed at enhancing the health and well-being of employees. Founded in 2010 and headquartered in Aliso Viejo, California, the company operates health centers across the United States, including Silicon Valley. Crossover Health provides a comprehensive range of services, including primary and urgent care, preventive care, chronic disease management, and various ancillary services such as physical therapy and health coaching. By focusing on customized health solutions based on health analytics, Crossover Health collaborates with employers to optimize benefit design and enhance employee engagement in their health. This approach aims to transform traditional healthcare models by reducing costs and improving care quality, ultimately fostering a healthier, more motivated workforce.

AnchorDx

Series C in 2021
Guangzhou Baseline Medical is committed to building a world-class clinical application of high-throughput sequencing and R & D platform to become the leading global provider of precision medical solutions. The company's core team has more than 20 years of senior industry experience, involved in cancer genomics, genetics and bioinformatics and other fields. Based on its core technical advantages, the Company aims at precision medicine, establishes a cooperative relationship with middle and downstream enterprises in the industry, and forms a complete industrial chain from academic research to clinical product transformation. It has also established close cooperation with many large-scale third-party inspection agencies including Illumina, Well-known domestic and foreign hospitals and research institutes to establish cooperative relations, the development of a series of independent intellectual property rights and international competitiveness of clinical testing products for patients, doctors and medical institutions to provide accurate, convenient and comprehensive services.

Delfi Diagnostics

Series A in 2021
Delfi Diagnostics, Inc. is a biotechnology company based in Baltimore, Maryland, that specializes in early cancer detection through non-invasive blood tests. Founded in 2018, the company utilizes advanced artificial intelligence and genome sequencing technologies to identify unique patterns of DNA fragmentation in patients' blood, enabling the detection of cancer at its most treatable stage. By focusing on precision diagnostics, Delfi Diagnostics aims to improve patient outcomes and contribute to the evolving landscape of cancer care.

MobileODT

Series C in 2020
MobileODT builds small, smart, connected visual diagnostic tools to enable any health provider, anywhere, to conduct examinations on the level of an expert practitioner. Empowering less-trained providers increases the reach of health systems, reducing costs, and improving outcomes. The Enhanced Visual Assessment (EVA) System is our first product, an FDA cleared internet-connected mobile colposcope and is growing rapidly in market share in the US, across Africa, and India. It is used in the world’s harshest environments and receives accolades from clinicians in the world’s leading hospitals (MD Anderson, Mount Sinai, Apollo). EVA has been used for over 40,000 procedures in 29 countries. Our customers include the world’s leading hospital groups West and East, and our fastest-growing market is the US, where we are becoming the standard for visualization (+20% of hospitals in New York State who offer Sexual Assault Forensic Examinations use EVA). We are growing rapidly in new geographies and have in the pipeline additional visual-based applications, including ENT, Oral disease, and Skin.

New Horizon Health

Series E in 2020
New Horizon Health, founded in 2015 and headquartered in Hangzhou, China, specializes in developing advanced technologies for the detection and screening of gastrointestinal cancers, particularly gastric and colorectal cancers. The company offers innovative products based on fecal gene analysis (FIT-DNA) technology, enabling users to conduct at-home tests that identify signs of colon cancer and significant adenomas. This technology facilitates earlier detection of precancerous lesions compared to conventional blood tests. By leveraging big data and artificial intelligence, New Horizon Health enhances its cancer screening solutions, aiming to improve public health outcomes. The company also emphasizes its commitment to making early cancer screening accessible to households, thereby striving to reduce the incidence and mortality associated with cancer.

TytoCare

Venture Round in 2020
TytoCare Ltd. develops handheld devices and application that connects people with doctor for an on-demand medical exam, diagnosis, and prescription if needed, anytime, and anywhere. The company’s tools help in examining the heart, lungs, skin, ears, throat, abdomen, and body temperature, and diagnose and treat various common conditions, such as ear infections, cold and flu, fever, headaches, eye irritation, congestion, sinus pain, allergies, sore throat, coughs and upper respiratory issues, bug bites and rashes, constipation, and stomachaches. TytoCare Ltd. has a strategic partnership with Novant Health. The company was incorporated in 2011 and is based in Netanya, Israel with an additional office in New York, New York.

TytoCare

Series C in 2018
TytoCare Ltd. develops handheld devices and application that connects people with doctor for an on-demand medical exam, diagnosis, and prescription if needed, anytime, and anywhere. The company’s tools help in examining the heart, lungs, skin, ears, throat, abdomen, and body temperature, and diagnose and treat various common conditions, such as ear infections, cold and flu, fever, headaches, eye irritation, congestion, sinus pain, allergies, sore throat, coughs and upper respiratory issues, bug bites and rashes, constipation, and stomachaches. TytoCare Ltd. has a strategic partnership with Novant Health. The company was incorporated in 2011 and is based in Netanya, Israel with an additional office in New York, New York.

MobileODT

Series B in 2017
MobileODT builds small, smart, connected visual diagnostic tools to enable any health provider, anywhere, to conduct examinations on the level of an expert practitioner. Empowering less-trained providers increases the reach of health systems, reducing costs, and improving outcomes. The Enhanced Visual Assessment (EVA) System is our first product, an FDA cleared internet-connected mobile colposcope and is growing rapidly in market share in the US, across Africa, and India. It is used in the world’s harshest environments and receives accolades from clinicians in the world’s leading hospitals (MD Anderson, Mount Sinai, Apollo). EVA has been used for over 40,000 procedures in 29 countries. Our customers include the world’s leading hospital groups West and East, and our fastest-growing market is the US, where we are becoming the standard for visualization (+20% of hospitals in New York State who offer Sexual Assault Forensic Examinations use EVA). We are growing rapidly in new geographies and have in the pipeline additional visual-based applications, including ENT, Oral disease, and Skin.

Guardant Health

Series E in 2017
Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

Suraksha Diagnostics

Venture Round in 2016
Established in 1992 as Suraksha Diagnostics & Eye Centre (P) Ltd. in Kolkata, they started as one of the first diagnostic centers in Kolkata to provide all pathology and radiology services under one roof. This convenience, along with their unwavering commitment to accuracy and service, resulted in steady growth and popularity. Within 3 years they could confidently open a second Center at Siliguri, in North Bengal, which remains the largest such facility in the region, and today serves not only to patients from North Bengal, but also neighbouring States and countries. Since then they have grown steadily across Bengal, Bihar, and Delhi NCR.

Nucleix

Seed Round in 2016
Nucleix develops, manufactures, and markets non-invasive molecular cancer diagnostic tests. Its sensitive and specific tests are based on identification of subtle changes in methylation patterns. Nucleix offers a urine test for monitoring of bladder cancer called Bladder EpiCheck and a blood test for early detection of lung cancer called Lung EpiCheck. Adam Wasserstrom, Danny Frumkin, and Elon Ganor founded it in 2008, with its headquarters in Rehovot in Israel.

Guardant Health

Series D in 2016
Guardant Health is committed to positively and significantly impacting patient health through technology breakthroughs that pointedly address long-standing unmet needs in oncology. Guardant is backed by Sequoia Capital, led by a seasoned management team comprising thought leaders and successful serial entrepreneurs in next-generation sequencing and rare-cell diagnostics and is closely advised by an oncologist-led medical steering committee from leading cancer centers across North America and abroad.

TytoCare

Series B in 2015
TytoCare Ltd. develops handheld devices and application that connects people with doctor for an on-demand medical exam, diagnosis, and prescription if needed, anytime, and anywhere. The company’s tools help in examining the heart, lungs, skin, ears, throat, abdomen, and body temperature, and diagnose and treat various common conditions, such as ear infections, cold and flu, fever, headaches, eye irritation, congestion, sinus pain, allergies, sore throat, coughs and upper respiratory issues, bug bites and rashes, constipation, and stomachaches. TytoCare Ltd. has a strategic partnership with Novant Health. The company was incorporated in 2011 and is based in Netanya, Israel with an additional office in New York, New York.

Natera

Series F in 2015
Natera is a diagnostic and research company specializing in genetic testing services, primarily focused on preconception and prenatal testing. Its flagship product, Panorama, is a non-invasive prenatal test that screens for chromosomal abnormalities in fetuses through a blood draw from the mother, including assessments for twin pregnancies. Other offerings include Vistara, which tests for single-gene disorders, and Horizon carrier screening to identify carrier status for various genetic diseases. Natera also provides the Anora test for analyzing fetal chromosomes in cases of miscarriage and non-invasive paternity testing. Additionally, the company has developed Signatera, a technology that detects circulating tumor DNA to monitor cancer recurrence. Natera utilizes a direct sales force and a network of approximately 100 laboratory and distribution partners for product distribution. The company was founded in 2003, has undergone several name changes, and is headquartered in San Carlos, California. Its collaborations with organizations like BGI Genomics and Foundation Medicine further enhance its capabilities in genetic testing and personalized medicine.

TytoCare

Series A in 2014
TytoCare Ltd. develops handheld devices and application that connects people with doctor for an on-demand medical exam, diagnosis, and prescription if needed, anytime, and anywhere. The company’s tools help in examining the heart, lungs, skin, ears, throat, abdomen, and body temperature, and diagnose and treat various common conditions, such as ear infections, cold and flu, fever, headaches, eye irritation, congestion, sinus pain, allergies, sore throat, coughs and upper respiratory issues, bug bites and rashes, constipation, and stomachaches. TytoCare Ltd. has a strategic partnership with Novant Health. The company was incorporated in 2011 and is based in Netanya, Israel with an additional office in New York, New York.

Natera

Series E in 2013
Natera is a diagnostic and research company specializing in genetic testing services, primarily focused on preconception and prenatal testing. Its flagship product, Panorama, is a non-invasive prenatal test that screens for chromosomal abnormalities in fetuses through a blood draw from the mother, including assessments for twin pregnancies. Other offerings include Vistara, which tests for single-gene disorders, and Horizon carrier screening to identify carrier status for various genetic diseases. Natera also provides the Anora test for analyzing fetal chromosomes in cases of miscarriage and non-invasive paternity testing. Additionally, the company has developed Signatera, a technology that detects circulating tumor DNA to monitor cancer recurrence. Natera utilizes a direct sales force and a network of approximately 100 laboratory and distribution partners for product distribution. The company was founded in 2003, has undergone several name changes, and is headquartered in San Carlos, California. Its collaborations with organizations like BGI Genomics and Foundation Medicine further enhance its capabilities in genetic testing and personalized medicine.

SuperDimension

Venture Round in 2010
SuperDimension is a privately-held medical device company that develops and markets minimally-invasive pulmonology devices that enable the diagnosis and potentially the treatment of distal lung disease. Our product line, the i·LogicTM System, includes both capital equipment and disposables, addressing a total available market of more than 8 million patients. Driven by our mission, "To be the world leader in the diagnosis and treatment of distal lung disease," we are focused on extending the capabilities of traditional bronchoscopy tools to help diagnose previously inaccessible lung lesions at an earlier stage when they may be easier to treat.

SuperDimension

Debt Financing in 2010
SuperDimension is a privately-held medical device company that develops and markets minimally-invasive pulmonology devices that enable the diagnosis and potentially the treatment of distal lung disease. Our product line, the i·LogicTM System, includes both capital equipment and disposables, addressing a total available market of more than 8 million patients. Driven by our mission, "To be the world leader in the diagnosis and treatment of distal lung disease," we are focused on extending the capabilities of traditional bronchoscopy tools to help diagnose previously inaccessible lung lesions at an earlier stage when they may be easier to treat.

SuperDimension

Series B in 2005
SuperDimension is a privately-held medical device company that develops and markets minimally-invasive pulmonology devices that enable the diagnosis and potentially the treatment of distal lung disease. Our product line, the i·LogicTM System, includes both capital equipment and disposables, addressing a total available market of more than 8 million patients. Driven by our mission, "To be the world leader in the diagnosis and treatment of distal lung disease," we are focused on extending the capabilities of traditional bronchoscopy tools to help diagnose previously inaccessible lung lesions at an earlier stage when they may be easier to treat.