Johnnie-O, Inc. is a lifestyle apparel company founded in 2005 by John O'Donnell and headquartered in Santa Monica, California. The brand specializes in designing and selling a wide range of clothing for men, women, and children, including polos, button-downs, bottoms, T-shirts, outerwear, swimwear, and accessories. Johnnie-O aims to blend the relaxed Southern California vibe with elements of East Coast tradition and Southern charm, appealing to customers seeking modern and quality attire. The company's products are available through various retail stores across the United States and online, catering to a diverse clientele interested in a casual yet stylish lifestyle.
Frequency Therapeutics is a clinical-stage biotechnology company based in Woburn, Massachusetts, dedicated to leveraging the body's natural biology to repair or reverse damage from various degenerative diseases. The company employs a unique Progenitor Cell Activation approach, utilizing combinations of small molecules to stimulate progenitor cells to regenerate functional tissue. Its lead product candidate, FX-322, is currently undergoing phase 2a clinical trials aimed at addressing the underlying causes of sensorineural hearing loss. In addition to hearing loss, Frequency Therapeutics is developing therapies for a variety of degenerative conditions, including multiple sclerosis and ailments affecting muscle, skin, gastrointestinal tract, and bone health. The company has also established a collaboration agreement with Astellas Pharma for the development and commercialization of FX-322. Founded in 2014, Frequency Therapeutics is focused on disease modification through innovative therapeutic strategies.
Medallia is a provider of customer and employee experience solutions through its SaaS platform, which captures experience data from various sources, including human, digital, and Internet of Things interactions. The platform employs artificial intelligence to analyze both structured and unstructured data, enabling organizations to gain insights into customer and employee sentiments. By utilizing the Medallia Experience Cloud, businesses can enhance customer retention, convert detractors into advocates, and identify real-time opportunities for cross-selling and upselling. Founded in 2001 and based in San Francisco, Medallia positions itself as a leader in customer experience and text analytics software, helping companies improve their operational performance and achieve significant returns on investment.
Quess Corp Ltd., India’s largest business services provider established in 2007. Headquartered in Bengaluru, the company has over 1,10,000 employees, serves over 1500 customers across 8 countries in more than 8000 locations. It has presence across 5 segments namely, Global Technology Solutions Group, Industrial Asset Management Group, Integrated Facilities Management Group, People Services & Logistics Group and Growth Businesses Group.
DocuSign, Inc. is a cloud-based software company that specializes in electronic signature solutions, enabling users to prepare, execute, and manage agreements digitally. Its platform automates various manual and paper-based processes, facilitating identity management, authentication, digital signatures, and workflow automation across multiple devices. The company offers a range of services, including DocuSign CLM for automating agreement workflows, Intelligent Insights for analyzing legal documents, and tailored industry-specific solutions such as Rooms for Real Estate and FedRAMP for U.S. federal agencies. Additionally, DocuSign provides training and support to its clients, which span small- and medium-sized businesses, enterprises, and individual users across various sectors, including finance, healthcare, and government. Founded in 2003 and headquartered in San Francisco, DocuSign has expanded its operations internationally with offices in cities such as London, Sydney, and Dublin.
DataStax, Inc. specializes in providing database software tailored for cloud applications, serving a diverse clientele that includes Fortune 100 companies globally. Its flagship product, DataStax Enterprise, enhances the capabilities of Apache Cassandra, offering fast performance and reliability for online applications. The company also features DataStax OpsCenter, a management and monitoring tool for database administrators, and K8ssandra, an open-source solution for deploying Cassandra on Kubernetes. Additionally, DataStax Astra offers a database-as-a-service platform that significantly accelerates deployment times, while DataStax Constellation streamlines the development and operation of modern applications. The company also provides training, support, and consulting services to ensure effective database management. Founded in 2010 and headquartered in Santa Clara, California, DataStax maintains a global presence with offices in several countries, including the United Kingdom, Japan, France, Germany, Australia, and Ireland.
Tethys BioScience, Inc. engages in the discovery, development, and commercialization of biological markers. Its products are used to diagnosis the metabolic diseases, such as diabetes. The company offers PreDx Diabetes Risk Test, a diagnostic test that analyzes a set of multiple proteins and other blood borne biomarkers implicated in the development of diabetes. Tethys BioScience, Inc. was founded in 2002 and is based in Emeryville, California.
Incipient is a company that specializes in developing enterprise-class storage solutions, focusing on storage area networks (SAN), storage virtualization, and automated data migration software. Its offerings include Automated Data Migration Software, which assists in various data migration projects such as data center relocations and storage array upgrades, and Network Storage Platform Software, which integrates storage virtualization with management capabilities for efficient data movement across SAN environments. Additionally, Incipient provides services such as automated storage provisioning, data copy services, and data protection solutions. The company targets markets related to data migration and storage management and distributes its products through channel partners. Founded in 2001, Incipient is headquartered in Waltham, Massachusetts.
Ocera Therapeutics is a clinical-stage biopharmaceutical company dedicated to developing innovative treatments for acute and chronic liver diseases, addressing significant unmet medical needs. The company's lead product, OCR-002, is an ammonia scavenger available in both intravenous and oral formulations, specifically targeting hyperammonemia. Ocera recently completed a Phase 2b clinical trial, known as STOP-HE, which assessed the safety and efficacy of OCR-002 in alleviating neurocognitive symptoms associated with acute hepatic encephalopathy in hospitalized patients with elevated ammonia levels. The company is planning to engage with the FDA to explore potential development pathways for its intravenous program later this year.
Orqis Medical
Series D in 2007
ORQIS Medical Corporation operates as a medical device company. It develops and sells minimally invasive devices for improving cardiac performance through aortic flow therapy. It offers Cancion System, a heart failure treatment that uses continuous aortic flow augmentation technology to improve symptoms of heart failure and change the underlying course of the disease for patients hospitalized for de-compensated heart failure. The company’s products also include Exeleras System to treat chronic heart failure patients.
Fluidigm Corporation develops and markets innovative technologies and tools for life sciences research globally. The company specializes in integrated fluidic circuits that control fluids at the nanoscale, enabling a range of applications in biological research. Its product offerings include analytical systems such as the Helios CyTOF system, the Hyperion imaging system, and the Biomark HD system, along with various assays and reagents designed for immuno-oncology and genetic analysis. Fluidigm also provides preparatory instruments and single-cell microfluidics, such as the C1 and Polaris systems. The company serves a diverse clientele, including academic institutions, clinical research laboratories, biopharmaceutical, biotechnology, and agricultural biotechnology companies, focusing on non-diagnostic and non-clinical applications. Established in 1999 as Mycometrix Corporation, it adopted the name Fluidigm Corporation in 2001 and is headquartered in South San Francisco, California.
Orexigen Therapeutics, Inc. is a biopharmaceutical company dedicated to developing pharmaceutical products for the treatment of obesity. Founded in 2002 and based in La Jolla, California, Orexigen's lead candidates include Contrave and Empatic. Contrave, which has completed Phase III clinical trials, is a combination of bupropion, an antidepressant, and naltrexone, used for treating addiction. Empatic, having completed Phase II clinical trials, combines bupropion with zonisamide, a medication used for epilepsy. Orexigen focuses on leveraging existing drugs to create effective treatments for weight management, emphasizing a scientific approach to addressing obesity.
BlueArc is a prominent provider of high-performance unified network storage systems tailored for enterprise and data-intensive markets. The company specializes in delivering storage hardware that supports both network-attached storage (NAS) and storage area network (SAN) services on a converged network storage platform. Its offerings include SiliconFS, a file system engine designed for efficient data movement, and JetClone, which facilitates data storage in virtual environments using a VMDK file structure. Additionally, BlueArc provides a suite of software solutions aimed at optimizing the performance of its storage systems, as well as tiered storage options that allow for the consolidation and deployment of various storage types within the same network-attached storage framework. The company's products serve a diverse range of sectors, including entertainment, federal government, higher education, internet services, oil and gas, and life sciences.
Inteliquent is a provider of network-based voice and messaging services aimed at wireless carriers, cable companies, competitive local exchange carriers (CLECs), and broadband service providers. The company operates an extensive tandem network that enhances the reliability of the Public Switched Telephone Network (PSTN) through tandem switch diversity and offers a cost-effective alternative to traditional tandem networks. Inteliquent's services include local transit, long-distance, switched access, international voice, direct inward dialing, and toll-free services, all delivered via an all-IP network. This infrastructure not only facilitates market entry for service providers but also supports the growth of their existing operations by reducing competitive tensions among carriers.
Incipient is a company that specializes in developing enterprise-class storage solutions, focusing on storage area networks (SAN), storage virtualization, and automated data migration software. Its offerings include Automated Data Migration Software, which assists in various data migration projects such as data center relocations and storage array upgrades, and Network Storage Platform Software, which integrates storage virtualization with management capabilities for efficient data movement across SAN environments. Additionally, Incipient provides services such as automated storage provisioning, data copy services, and data protection solutions. The company targets markets related to data migration and storage management and distributes its products through channel partners. Founded in 2001, Incipient is headquartered in Waltham, Massachusetts.
Nanosys, Inc. specializes in developing and manufacturing quantum dot technology to enhance high-definition viewing experiences in the display industry. Founded in 2001 and based in Milpitas, California, the company offers a range of products, including Quantum Dot Concentrate material, quantum dot nanomaterials, and Quantum Dot Enhancement films. These products improve color performance and brightness in a variety of consumer electronics, such as tablets, televisions, smartphones, and automotive interiors. Nanosys' quantum dot technology is compatible with various display types, including LED-LCDs, OLEDs, and micro-LEDs, and has been integrated into over 20 million devices across more than 400 unique products. The company also explores applications of its nanotechnology in areas beyond displays, such as agriculture.
Ophthonix, Inc. manufactures and markets high resolution spectacle lenses for vision assessment and correction applications. It offers its high resolution lenses for single vision spectacle lenses for the correction of myopia, hyperopia, and mild astigmatism; and progressive addition spectacle lenses. The company sells its products through practitioners in the United States and European countries. Ophthonix, Inc. was founded in 2000 and is based in Vista, California.
TherOx, Inc. is a medical device company based in Irvine, California, focused on enhancing the treatment standards for heart attack patients. Founded in 1994, the company specializes in developing and manufacturing dissolved oxygen delivery systems, specifically through its proprietary SuperSaturated Oxygen Therapy (SSO2). The TherOx DownStream system is a mobile device that works in conjunction with a cartridge and console to create a superoxygenated solution mixed with the patient’s blood, which is then delivered to the coronary arteries. This innovative approach aims to restore blood flow and promote healing in damaged heart tissue. In addition to its primary application in heart attack treatment, TherOx has identified potential uses for its technology in other medical fields, including stroke, oncology, and wound care. The company holds 20 issued patents, with additional applications pending. As of June 2019, TherOx operates as a subsidiary of ZOLL Medical Corporation.
BlueArc is a prominent provider of high-performance unified network storage systems tailored for enterprise and data-intensive markets. The company specializes in delivering storage hardware that supports both network-attached storage (NAS) and storage area network (SAN) services on a converged network storage platform. Its offerings include SiliconFS, a file system engine designed for efficient data movement, and JetClone, which facilitates data storage in virtual environments using a VMDK file structure. Additionally, BlueArc provides a suite of software solutions aimed at optimizing the performance of its storage systems, as well as tiered storage options that allow for the consolidation and deployment of various storage types within the same network-attached storage framework. The company's products serve a diverse range of sectors, including entertainment, federal government, higher education, internet services, oil and gas, and life sciences.
Metro-Optix develops hardware for telecommunications companies that want to transition from circuit-based services to cell- and packet-based services. The hardware essentially reduces the number of hardware boxes needed, such as routers, which the networks feed into.
Verticore Technologies have been developing applications to improve the way organizations use and manage their knowledge and work processes. Leveraging this extensive experience, in June 1998 they launched the development of a unique framework designed to facilitate the rapid creation of a suite of browser-based applications to manage work processes and knowledge, and improve employee productivity. The framework addressed such critical factors as improved scorekeeping, clear goals, frequent feedback, participation, choice, and collaborative environments.
Metro-Optix develops hardware for telecommunications companies that want to transition from circuit-based services to cell- and packet-based services. The hardware essentially reduces the number of hardware boxes needed, such as routers, which the networks feed into.