Boundless Bio, Inc., biopharma company, develops therapies and medicines for the treatment of cancers. It offers therapeutics based on extrachromosomal DNA (ecDNA) one of the drivers of the aggressive cancers, such as cancers characterized by high copy number amplification of oncogenes. The company was formerly known as Pretzel Therapeutics, Inc. Boundless Bio, Inc. was founded in 2018 and is based in LA Jolla, California.
Quince is a new e-commerce company that focuses on leveraging an M2C supply chain to deliver premium essentials at the lowest market price. It acts as a thin storefront to bring manufacturers and artisans closer to their customers through shared partnership in brand or marketing. The company was founded in 2018 and is headquartered in San Francisco, California.
AMP Robotics Corporation specializes in designing and manufacturing robotic systems for material recovery facilities and recycling operations, focusing on automating the identification, sorting, and processing of complex waste streams. The company's flagship product, AMP Cortex, utilizes advanced robotics and computer vision technology to efficiently pick and sort recyclable materials, significantly lowering sorting costs. Additionally, AMP Neuron, a software solution, captures and analyzes material data to identify features in a manner similar to human perception. By leveraging artificial intelligence and machine learning, AMP Robotics enhances recycling processes for various waste types, including municipal solid waste and e-waste. The modular design of its systems allows for easy integration into existing infrastructure, minimizing disruption and capital investment. Founded in 2014 and headquartered in Louisville, Colorado, AMP Robotics has formed strategic partnerships to further its mission of improving recycling rates and economic recovery of recyclables.
Saluda Medical Pty Ltd., established in 2013 and headquartered in Artarmon, Australia, focuses on developing innovative medical devices for the neuromodulation industry. The company's flagship product, Evoke, is an investigational closed-loop spinal cord stimulation system designed to measure and adapt to the spinal cord's response to stimulation. By adjusting the stimulation on every pulse, Evoke aims to optimize therapeutic outcomes for patients within their individualized treatment parameters. Saluda Medical's foundation is built on years of research from Australia's NICTA and is supported by a team of experienced engineers, clinicians, and professionals dedicated to advancing medical technologies. The company also has offices in Bloomington, Minnesota, and Harrogate, United Kingdom.
RayzeBio, Inc. is a biotechnology company based in San Diego, California, founded in 2020. The company specializes in developing tumor-targeted small molecule medicines that utilize radioisotopes, particularly focusing on alpha-emitting isotopes like Actinium-225 for the treatment of solid tumors. RayzeBio aims to improve cancer treatment outcomes by creating a robust pipeline of radiopharmaceuticals targeting validated oncology drug targets. Its portfolio includes multiple drug candidates at various stages of development, ranging from discovery to late-stage clinical programs, addressing significant market opportunities in the field of cancer therapeutics.
Meati, also known as Emergy Foods, is a consumer goods company based in Boulder, Colorado, founded in 2016. The company specializes in producing whole muscle, nutritious plant-based meats designed to promote healthier lifestyles and environmental sustainability. By utilizing proprietary, clean technologies, Meati offers nutrient-dense meat alternatives that aim to appeal to a wide audience, ensuring that consumers can enjoy meals that are both good for their health and the planet.
Moving Analytics. is a tele-health company dedicated to helping people thrive after heart disease. Our flagship product is Movn a virtual cardiac rehabilitation program that leverages evidence based guidelines, behavioral science, remote monitoring and personalized coaching to help patients recover to full health after a cardiac event. Movn is currently used by the Veterans Affairs Medical Center, Highmark Health Plan, Kaiser Permanente Northwest and many more health systems across the US.
FalconX, Ltd. is a digital asset trading platform based in San Francisco, California, that specializes in providing trading solutions using data science and blockchain technology. Founded in 2018, the company has rapidly established itself in the market, achieving $7 billion in global trading volume over a recent ten-month period, with a quarterly growth rate exceeding 600%. FalconX caters to a diverse clientele, including over 100 financial institutions such as hedge funds, proprietary trading firms, payment gateways, and cryptocurrency exchanges. The platform is designed to offer reliable execution for mid-to-large size trades, employing machine learning to optimize trade execution by smart routing orders across various liquidity sources. This approach helps clients minimize slippage and eliminate hidden fees, facilitating efficient currency exchange and transfer within the cryptocurrency markets.
Guild Education's lifelong learning platform offers classes, programs and degrees for working adults, with a path for them to move forward in their education and career. Guild offers these adults support from start to finish, with their technology platform for discovery, learning, and organizing the experience, and extra support with their tech-enabled student advising model.
Founded in 2015, the company is headquartered in Denver, Colorado, United States.
Arcadia, Inc. is an online platform based in Washington, D.C., that facilitates the management of energy accounts for residential and commercial users across the United States. Founded in 2013, the company connects subscribers to renewable energy sources, including wind farms and community solar projects. Through its application, users can easily sign up for clean energy options available in their area and monitor their energy usage and account activity. Arcadia aims to enhance the utility experience by providing seamless monthly billing and access to energy-efficient products, thereby promoting clean energy and cost savings for its customers.
Span.IO, Inc. specializes in renewable energy products for residential use, focusing on smart electrical panels that serve as the central hub for managing home energy. Founded in 2018 and headquartered in San Francisco, the company also offers an application called The Span, which allows homeowners to monitor and control their energy consumption remotely, schedule usage, and receive alerts. Span.IO aims to facilitate the transition to clean energy through innovative technology that enhances user experience while promoting sustainability. The company collaborates with installers, technology providers, and energy companies to reach homeowners and is driven by a team of engineers committed to creating impactful solutions in the energy sector.
Omada Health, Inc. is a digital healthcare company that develops online programs aimed at managing chronic conditions. Founded in 2011 and headquartered in San Francisco, with an additional office in Atlanta, the company collaborates with employers and health plans to identify individuals at risk for preventable chronic conditions such as prediabetes, diabetes, hypertension, and heart disease. Omada's programs are personalized to address the evolving needs of participants, offering support in areas like diabetes prevention, type 2 diabetes management, and behavioral health. The company integrates professional health coaching, connected health devices, real-time data, and personalized feedback to achieve clinically significant outcomes. Omada Health is recognized as the largest provider of the National Diabetes Prevention Program by the Centers for Disease Control and Prevention (CDC).
Somatus is a healthcare company that partners with health plans, health systems, and nephrology, and primary care groups. It provides integrated care for patients with or at risk of developing kidney disease. Somatus' is vertically integrated clinical services and technology delay or prevent disease progression, improve quality and care coordination, and increase the use of home dialysis modalities and rates of kidney transplantation.
The company is headquartered in McLean, Virginia, and founded by a team of world-class healthcare operators, successful entrepreneurs, and leading clinicians treating kidney disease.
Synthego is a genome engineering company that enables the acceleration of life science research and development in the pursuit of improved human health.
The company leverages machine learning, automation, and gene editing to build platforms for science at scale. With its foundations in engineering disciplines, the company’s full-stack platform vertically integrates proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance both basic research and therapeutic development programs.
By providing both commercial and academic researchers and therapeutic developers with unprecedented access to cutting-edge genome engineering, Synthego is at the forefront of innovation, accelerating the development of truly engineered biology.
The company was founded in 2012 and is based in Redwood City, California.
Creditas is a financial technology company based in São Paulo, Brazil, specializing in secured consumer loans. Founded by Sergio Furio, the company operates a digital platform that leverages credit scoring and borrower assets, such as homes and automobiles, as collateral to provide loans. This approach allows Creditas to offer affordable lending solutions by partnering with traditional financial institutions and utilizing investor-backed resources. The platform is designed to enable borrowers to repay their loans in manageable installments, thereby making financing more accessible.
CodeSee analyzes the data flowing through your system to maintain an updated map of your system architecture, its components, and the connections between them. Developers can explore at a high level, or dive in and see the data right next to the code. In other words...We make grokking a codebase easy. Developers stop feeling like outsiders and start feeling like high performers. Faster.
Go Digit General Insurance Limited is a digital insurance company based in Bengaluru, India, founded in 2016 by Kamesh Goyal. The company offers a wide range of insurance products, including car, travel, home, commercial vehicle, bike, health, mobile, and shop insurance, as well as flight delay coverage. Go Digit focuses on enhancing customer experience through its online platform, which facilitates claims, renewals, and provides information on motor vehicle and health insurance. The company is known for its innovative approach to insurance, aiming to simplify products and pricing processes. It operates as a subsidiary of Go Digit Infoworks Services Private Limited and generates significant revenue from its motor insurance offerings.
Dave Inc. is a financial services company based in Los Angeles, California, founded in 2015. The company has developed a mobile application designed to assist users in managing their finances by providing insights into bank overdrafts and predicting expenses. The app enables users to avoid overdraft fees and low balances by offering features such as paycheck advances, budgeting tools, and resources for finding side gigs. With a focus on helping users maintain financial stability, Dave serves approximately 7 million Americans by providing essential tools for budgeting and credit building. The application is accessible on both the App Store and Google Play, positioning Dave as a key player in the challenger bank space.
Rokt is a leading provider of e-commerce technology that enhances the customer buying experience by integrating marketing into the transaction moment. The company works with prominent brands like Live Nation, Groupon, and GoDaddy to deliver tailored advertising at critical points during the purchasing process. This approach enables e-commerce businesses to boost brand engagement, unlock new revenue streams, and improve overall customer experiences. Founded in Sydney, Rokt has expanded its operations globally, serving clients across various regions, including North America, Europe, and Asia. Its proprietary technology aims to connect advertisers with customers at opportune moments, facilitating effective upselling and cross-selling opportunities while keeping businesses competitive in the rapidly evolving e-commerce landscape.
Olist is an online e-commerce platform based in Curitiba, Brazil, that facilitates connections between sellers and major Brazilian marketplaces. Founded in 2015, the company provides a comprehensive platform for shopkeepers of various sizes and sectors to register and sell their products through prominent retailers. Olist aims to streamline the selling process for entrepreneurs by enabling them to advertise and sell their products without complications, thereby enhancing their reach to international marketplaces. The company emphasizes a sustainable and fair business model, focusing on delivering excellent services to both merchants and consumers.
Anchorage is the first crypto-native Qualified Custodian for institutional investors, offering a comprehensive platform complete with trading, staking, and governance. Co-founded by security engineers from Square and Docker, Anchorage has raised $57 million in funding from such leading investors as Visa and Andreessen Horowitz, and counts as clients many of crypto’s largest and best-known funds, including Blockchain Capital, BlockTower, Polychain, and Paradigm. It was founded in 2017 and is headquartered in San Francisco, California.
Learneo brands and platforms are pioneering advances in a wide range of applications for emergent technologies, including the use of AI to improve people's writing, reading and math skills, in school, professional and daily life. The platform of businesses includes CliffsNotes, the original and iconic study guide company; Course Hero, an online learning platform of academic resources; LitCharts, a creator of literature resources; QuillBot, an AI-powered writing companion helping anyone improve their writing skills; Scribbr, a multilingual academic proofreading service, and Symbolab, an AI-based mathematics resource. Learneo was established in Redwood City, California by Andrew Grauer and Gregor Carrigan.
Chroma Medicine is a new genomic medicine company working on epigenetic editing. Chroma Medicine is pioneering a new class of genomic medicines that harness epigenetics, nature’s innate mechanism for gene regulation, to revolutionize the treatment of genetically driven diseases.
Faire Wholesale, Inc. develops and operates an online marketplace which connects independent retailers with manufacturers of the products. It offers Indigo Fair, a wholesale marketplace that enables retailers to browse items from various makers, place wholesale orders, and track shipments online. Faire Wholesale, Inc. was founded in 2016 and is based in San Francisco, California with an additional office in Kitchener, Canada.
BetterUp Inc. is a leadership development platform based in San Francisco, California, founded in 2013. The company provides a mobile-based solution for organizations, including Fortune 500 companies, aimed at enhancing employee performance through a science-backed methodology. BetterUp's platform facilitates on-demand virtual coaching sessions, allowing users to identify and practice new behaviors and mindsets essential for achieving high performance in a rapidly changing environment. The platform tracks and measures individual growth, helping employees cultivate skills that support both personal and professional development. Its diverse clientele includes notable companies like Genentech, Logitech, and Workday, reflecting its commitment to fostering an adaptive workforce.
Ventyx Biosciences, Inc. is a biotechnology company based in Encinitas, California, focused on developing selective inhibitors of TYK2 for the treatment of autoimmune diseases. Incorporated in 2018, the company boasts a diverse portfolio of innovative clinical and pre-clinical programs aimed at high-value therapeutic targets. Through its research and development efforts, Ventyx is committed to advancing treatments that address unmet medical needs in the autoimmune disease space.
Archaea Energy is an emerging leader in developing renewable natural gas (“RNG”) which is a sustainable decarbonizing solution for high-carbon emission processes and industries that are impossible or inefficient to electrify.
Arcadia, Inc. is an online platform based in Washington, D.C., that facilitates the management of energy accounts for residential and commercial users across the United States. Founded in 2013, the company connects subscribers to renewable energy sources, including wind farms and community solar projects. Through its application, users can easily sign up for clean energy options available in their area and monitor their energy usage and account activity. Arcadia aims to enhance the utility experience by providing seamless monthly billing and access to energy-efficient products, thereby promoting clean energy and cost savings for its customers.
SpotOn is a payments and software company redefining the merchant services industry. The company brings together payment processing and customer engagement software, giving merchants richer data and tools that empower them to market more effectively to their customers. Its platform offers tools for small and medium businesses, including payments, marketing, reviews, analytics, and loyalty, backed by industry-leading customer care. Doron Friedman, Matt Hyman, and Zach Hyman co-founded SpotOn in 2017 and its headquarters is located in San Francisco, California.
Asher Biotherapeutics, Inc. is a biotechnology company focused on developing immunotherapy drugs for cancer treatment. Founded in 2019 and headquartered in South San Francisco, California, the company aims to create innovative therapeutic solutions to improve patient outcomes in oncology. Asher Bio leverages advanced technologies and research to enhance the effectiveness of immune-based therapies, positioning itself as a key player in the evolving field of cancer treatment.
Trove is a technology-driven platform based in Brisbane, California, that specializes in launching and reselling business and brands. The company provides a range of services, including storefront design, product photography, cleaning and repair, authentication, and customer service. By offering white-label technology and end-to-end operations, Trove empowers premium and luxury brands like Levi’s, Patagonia, and REI to manage their own resale marketplaces. This approach allows brands to reclaim items from customers while maintaining control over their brand equity and customer relationships. Committed to sustainability, Trove seeks to promote circular shopping, enabling consumers to access high-quality products with reduced waste.
Strata Oncology is a precision oncology company dedicated to transforming cancer care by expanding patient access to precision medicine clinical trials and accelerating drug approval.
Strata's national precision oncology platform serves the needs of patients, providers and drug developers by providing a link from patient screening to streamlined enrollment in mutation-matched clinical trials. Follow us on Twitter @StrataOncology.
Lucid Motors Inc. is an electric vehicle manufacturer based in Menlo Park, California, with a manufacturing facility in Casa Grande, Arizona. Founded in 2007 and initially known as Atieva, Inc., the company rebranded to Lucid Motors in 2016. Lucid Motors aims to enhance the driving experience by creating vehicles that prioritize performance, space, and intelligence. The company emphasizes intuitive design and user experience, striving to redefine mobility by focusing on the individual needs of drivers. To support its electric car production, Lucid Motors has established strategic partnerships with prominent battery manufacturers Samsung SDI and LG Chem.
Keeping technology at the core, Zinka Logistics is redefining the logistics landscape of India, making it reliable and efficient. Our comprehensive approach to problems creates impact on the entire ecosystem of transportation, which stitches across large number of livelihoods. The transportation sector is ripe for a revolution, and Zinka Logistics marks the beginning.
Sundae operates a home-selling platform designed to assist homeowners in selling houses that are outdated or in need of repairs. The company addresses the challenges faced by sellers in a traditional real estate market, where local investors often exploit homeowner distress to acquire properties at low prices. Sundae aims to provide a better outcome for these sellers by offering competitive off-market prices without the need for cleanup, repairs, or showings. Through a data-driven model, Sundae anticipates when homeowners may require assistance and employs a skilled sales and marketing team to effectively reach them. By prioritizing the needs of sellers and redistributing economic value, Sundae strives to become a leading buyer of homes that require significant attention across the United States.
HYZON Motors Inc manufactures hydrogen-powered trucks and buses. It offers city and coach buses, medium duty trucks, and heavy duty trucks. The company was founded in 2020 and is based in Honeoye Falls, New York.
Markforged, founded in 2013 and based in Watertown, Massachusetts, specializes in designing and manufacturing advanced 3D printers that utilize materials such as carbon fiber, metal, fiberglass, nylon, and PLA filament. The company's printers are engineered to produce durable parts, tooling, fixtures, and functional prototypes suitable for industrial applications. Markforged also offers EIGER, its proprietary 3D printing software, which enhances the printing process. With a global workforce of approximately 300 employees, the company has attracted significant investment, totaling around $137 million. Markforged has garnered recognition for its innovative contributions to manufacturing, including being featured in Forbes' Next Billion-Dollar Startups list and ranking as one of the fastest-growing hardware companies in the United States according to Deloitte's Fast 500.
Swiggy designs an on-demand food delivery platform that brings food from neighborhood restaurants directly to users' doors. The company's food delivery platform lists local restaurants and menu lists on an app for users to order from and track delivery of its delivery executives, enabling users to order food with speed and convenience. Its service is used to pick up and drop off a diverse array of items, including laundry and document or parcel deliveries to business clients and retail customers. Swiggy was founded by Sriharsha Majety, Nandan Reddy, and Rahul Jaiminiin in 2014 and is headquartered in Bangalore, Karnataka, India.
EVgo Services LLC owns and operates network of fast chargers for electric vehicles. It operates charging stations compatible with all fast charge capable electric vehicle models. The company was incorporated in 2010 and is based in Los Angeles, California.
Payoneer Inc. operates a cross-border payments platform designed to facilitate global commerce by connecting businesses, professionals, countries, and currencies. Founded in 2005 and headquartered in New York, the company offers products such as the Global Payment Service, which provides users with local receiving accounts in the United States, European Union, and Japan, allowing for direct local bank transfers. Additionally, Payoneer enables users to receive payments from various integrated partners, including those in freelance, e-commerce, and online advertising sectors. The company also provides mass payout services that assist Indian companies in transferring funds internationally. Serving millions of users across over 200 countries, Payoneer is a trusted partner for numerous prominent corporations, making cross-border payments as straightforward as local transactions.
Perella Weinberg Partners is an independent, privately-owned financial services firm that provides corporate advisory and asset management services to clients around the world. The Firm has assembled a group of talented and experienced professionals recruited from a wide variety of leading global financial institutions.
Launched in 2006, the company is divided into two business units: corporate advisory, which provides services to decision makers in business and government, and asset management, which consists of investment vehicles catering to institutional investors.
Lendbuzz Funding, LLC offers car loans to expats and international students. The company does not require Social Security Number (SSN) and provides loans to all visa holders from all nationalities. Its customers include students, international professionals, and other young professionals that have an international credit file. The company provides access and manages its loans through an online platform and data-intensive scoring technology. Lendbuzz Funding, LLC was founded in 2015 and is based in Boston, Massachusetts.
Faire Wholesale, Inc. develops and operates an online marketplace which connects independent retailers with manufacturers of the products. It offers Indigo Fair, a wholesale marketplace that enables retailers to browse items from various makers, place wholesale orders, and track shipments online. Faire Wholesale, Inc. was founded in 2016 and is based in San Francisco, California with an additional office in Kitchener, Canada.
Latch makes access easier for everyone at a modern building. The company specializes in manufacturing keyless entry security system giving property owners the ability to manage every door in a multi-family building. Moreover, residents can also give access to guests as well as service providers through time-limited access codes. Latch is headquartered in New York, New York, United States.
NiKang Therapeutics, Inc. is a biotechnology company established in 2017 and located in Wilmington, Delaware. The company is dedicated to discovering and developing innovative small molecule oncology medicines aimed at addressing unmet medical needs in cancer treatment. By employing a discovery approach that leverages target structure biology and structure-based drug design, NiKang Therapeutics aims to facilitate the rapid and efficient development of proprietary drug candidates with optimal pharmacological properties. The company seeks to enhance the treatment options available to healthcare providers, ultimately improving patient outcomes in the fight against cancer.
Snapdocs, Inc. is a real estate technology company that provides a digital platform designed to streamline the mortgage closing process. Founded in 2012 and based in San Francisco, California, Snapdocs connects lenders, title and escrow companies, notary publics, and home buyers to enhance collaboration and efficiency in real estate transactions. The platform features advanced automation and standardized workflows, allowing participants to choose their preferred closing methods while improving accuracy and consumer satisfaction. It also enables notary signing agents to showcase their qualifications, helping them attract potential clients. By simplifying mortgage loan closings and improving the overall borrower experience, Snapdocs empowers its users to operate more effectively and transparently in a competitive market.
Nuvalent is a biotechnology company that develops targeted therapies for clinically proven kinase targets in cancer. Leveraging deep expertise in structure-based design, Nuvalent develops innovative small molecules with exquisite target selectivity to overcome resistance, minimize adverse events, and drive more durable responses. It is advancing a robust pipeline with parallel lead programs in ROS1-positive and ALK-positive NSCLC, along with multiple discovery-stage research programs. It was founded in 2017 and is based in Cambridge, Massachusetts.
Oxford Nanopore Technologies Limited specializes in the development and commercialization of nanopore-based electronic systems for the analysis of single molecules, particularly in the fields of DNA and RNA sequencing. The company offers a range of products, including the portable MinION device for molecular analysis, the benchtop PromethION for large-scale sequencing projects, and the GridION system suitable for various molecular sensing applications. Their technology supports diverse scientific research areas such as genomics, cancer studies, microbiology, and environmental research, with applications extending to healthcare, agriculture, and food safety. The Flongle device caters to on-demand sequencing needs, while the MinIT accessory enhances the functionality of their sequencing devices. Oxford Nanopore’s innovative technology emphasizes accessibility and ease of use, with rapid library preparation and automated processes. Founded in 2005 and headquartered in Oxford, United Kingdom, the company operates additional offices worldwide, enabling its products to be utilized in over 80 countries.
Boundless Bio, Inc., biopharma company, develops therapies and medicines for the treatment of cancers. It offers therapeutics based on extrachromosomal DNA (ecDNA) one of the drivers of the aggressive cancers, such as cancers characterized by high copy number amplification of oncogenes. The company was formerly known as Pretzel Therapeutics, Inc. Boundless Bio, Inc. was founded in 2018 and is based in LA Jolla, California.
UrbanClap Technologies India Pvt. Ltd., now known as Urban Company, operates a leading online platform for home services in Asia, facilitating connections between customers and service professionals. Launched in November 2014 and based in Gurugram, India, the platform offers a diverse range of services, including beauty treatments, massage therapy, cleaning, plumbing, carpentry, appliance repair, and painting. Users can easily find and hire professionals such as wedding photographers, fitness trainers, and interior designers, among others. The platform provides features that allow customers to compare quotes, review profiles, and assess the experience of service providers. Urban Company serves major cities including Delhi NCR, Bengaluru, Mumbai, Chennai, Pune, and Hyderabad, and has expanded its reach to international markets like the UAE, Singapore, and Australia. The company is dedicated to empowering service professionals by offering them training, credit, and technological support.
Greenlight Financial Technology, Inc. is a financial services company that offers debit card solutions designed specifically for children, enabling parents to instill financial literacy from an early age. Founded in 2014 and headquartered in Atlanta, Georgia, Greenlight provides a mobile application that allows parents to manage their children’s spending by designating specific stores where the Greenlight debit card can be used. This patent-pending technology empowers families to create teachable moments around earning, saving, spending, and giving. By focusing on convenience and safety, Greenlight aims to help parents raise financially savvy children while also expanding its network across the United States.
Current is a leading U.S. challenger bank built to meet the needs of people with unique lives who have been overlooked by the traditional banking industry. Our proprietary Current Core technology allows us to provide premium banking services for everyone, regardless of age or income, and improve the financial outcomes of our members without overdraft fees, minimum balance requirements, or hidden fees. We give members up to two days faster direct deposit paychecks, free overdrafts up to $100 with Overdrive™ , points on purchases redeemable for cash back, access to 55,000 free ATMs worldwide as well as 24/7 member support 365 days a year.
Scale AI, Inc. is a data platform that specializes in providing high-quality training and validation data for artificial intelligence applications. Founded in 2016 and based in San Francisco, the company offers a range of annotation tools, including platforms for 3D sensor data, images, videos, text, and documents. Its products support various AI tasks such as content moderation, transcription, and data comparison, and are utilized across multiple sectors including autonomous vehicles, retail, conversational AI, and robotics. Scale AI's technology enables companies to streamline their machine learning processes, allowing teams to concentrate on developing innovative models rather than the labor-intensive task of data labeling. The company serves notable clients in the technology and transportation industries, enhancing the efficiency and effectiveness of AI development.
Patreon Inc. operates a membership platform designed to help content creators and artists fund their work. Founded in 2013 and based in San Francisco, California, Patreon.com facilitates connections between users and provides access to various types of content, including videos, photographs, artwork, audio clips, and more. The platform allows patrons to pledge support to their favorite creators on a recurring basis, thereby empowering a new generation of artists to earn a living from their passions. By enabling direct financial support from fans, Patreon fosters a sustainable ecosystem for creative individuals to thrive.
Swiggy designs an on-demand food delivery platform that brings food from neighborhood restaurants directly to users' doors. The company's food delivery platform lists local restaurants and menu lists on an app for users to order from and track delivery of its delivery executives, enabling users to order food with speed and convenience. Its service is used to pick up and drop off a diverse array of items, including laundry and document or parcel deliveries to business clients and retail customers. Swiggy was founded by Sriharsha Majety, Nandan Reddy, and Rahul Jaiminiin in 2014 and is headquartered in Bangalore, Karnataka, India.
Scribe Therapeutics Inc. engages in the engineering, delivery, and development of in vivo therapies and CRISPR molecules to rewrite and repair the underlying cause of genetic disorders. Its technology includes X-Editing (XE), an engineered molecule for therapeutic use and in vivo genetic modification. The company was incorporated in 2017 and is based in Berkeley, California.
Paidy Inc. is a Tokyo-based company that offers a cardless payment platform for online shopping. Founded in 2008 and formerly known as Exchange Corporation K.K., Paidy allows consumers to make purchases using just their name and email address, eliminating the need for credit cards or pre-registration. The service is designed for mobile and instant-checkout, enabling users to buy online and settle their payments through a consolidated monthly bill. Paidy employs proprietary technology to assess creditworthiness, underwrite transactions, and ensure payment to merchants. This innovative approach caters to Japanese consumers who prefer not to use credit cards, thereby helping online vendors enhance their conversion rates, increase average order values, and encourage repeat purchases.
Entrada Therapeutics, Inc., a biotechnology company, engages in the treatment of diseases through the intracellular delivery of biologic. The company enables intracellular delivery of proteins, peptides, and nucleic acids and allows development of programs across intracellular target classes. Its Intracellular enzyme replacement therapy (IC-ERT) is a medical treatment that corrects an enzyme deficiency in the cell, Protein-Protein Interaction Inhibitors. The company was founded in 2016 and is based in Boston, Massachusetts.
Cityblock Health is a healthcare provider focused on delivering primary care, behavioral health, and virtual care services to lower-income communities. Established in 2017 and based in Brooklyn, New York, Cityblock leverages technology to offer personalized, prevention-oriented care for urban residents with complex health needs. The company's platform facilitates access to preventive visits, mental health services, and social support programs. Additionally, Cityblock offers a communication tool called Commons, which enhances information sharing and task management among members and care teams. During the COVID-19 pandemic, Cityblock developed a model to identify individuals at high risk, highlighting its commitment to addressing urgent health challenges. By prioritizing upstream investments in health and social care, Cityblock aims to improve health outcomes while reducing overall costs.
Arrival Limited is a technology company based in London that specializes in manufacturing electric vehicles. Founded in 2015, the company focuses on developing software, materials, components, and scalable skateboard platforms, which serve as the foundation for its electric vehicles. Arrival's innovative approach includes the use of micro-factories, enabling efficient production and adaptation to various mobility ecosystems while minimizing capital expenditure. This model allows the company to produce zero-emission vehicles tailored to the needs of urban environments and aims to enhance public transportation through intelligent design. In addition to its headquarters in the United Kingdom, Arrival operates offices in Germany, the Netherlands, Israel, Russia, and the United States.
Artiva Biotherapeutics, Inc., a biotech company, develops and manufactures cellular immunotherapies for cancer patients. The company offers a pipeline of off-the-shelf, allogeneic natural killer (NK) cell therapies for the treatment of hematologic cancers or solid tumors. The company’s products target CD20 and CD19 in B-cell lymphomas and HER2 in various solid tumors. The company was founded in 2019 and is headquartered in San Diego, California. Artiva Biotherapeutics, Inc. operates as a subsidiary of Green Cross Holdings Corporation.
Centessa Pharmaceuticals is a next-generation biopharmaceutical company that aims to reshape the traditional drug development process. The company applies an asset-centric R&D model at scale to advance a portfolio of highly validated programs led by industry-leading teams. Each program is developed by a Centessa Subsidiary and supported by a centralized infrastructure and the Centessa management team.
Butterfly Network designs a medical imaging device that reduces the cost of real-time and three-dimensional imaging and treatment. Jonathan M. Rothberg, Nevada Sanchez, and Tyler S. Ralston founded it in 2011, with its headquarters in Guilford in Connecticut.
Gemini Therapeutics, Inc. is a precision medicine company established in 2015 and based in Cambridge, Massachusetts. The company specializes in developing therapies for patients with dry age-related macular degeneration (AMD) and related rare genetic diseases. Gemini's approach focuses on addressing genetically-defined conditions by creating therapeutic candidates that target specific molecular abnormalities prevalent in patients with significant clinical needs. Their diverse pipeline features a range of innovative treatment modalities, including monoclonal antibodies, recombinant proteins, and gene therapies. The company has secured funding from prominent life science investors and collaborates with academic institutions globally to advance its mission of delivering potentially first-in-class therapeutics.
Design Therapeutics, Inc. develops therapies for the treatment of degenerative disorders caused by nucleotide repeat expansions. The company engages in the development of a program for the treatment of Friedreich’s ataxia and degenerative diseases such as Fragile X syndrome and myotonic dystrophy. The company was incorporated in 2017 and is based in Solana Beach, California.
Private Equity Round in 2021
PPRO provides access, processing, and collection services for alternative payment methods and value added services. Founded in 2006, their vision from the start has been to simplify access to the many different payment methods required by consumers and businesses across the world. Today they offer a full range of flexible services for payment industry leaders as well as e-money issuing programs for consumers and corporate. Headquartered in the UK, they are FCA licensed to issue e-money, are principal members of Mastercard and VISA and continue to strengthen their links with alternative payment method schemes and banks around the world.
Verve Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to reduce the risk of coronary artery disease, a leading cause of death globally. Founded in 2018 and headquartered in Cambridge, Massachusetts, with a research facility in Philadelphia, the company leverages human genetic analysis and gene-editing technologies to create treatments that offer lifelong protection from this condition. Verve has established strategic alliances, including collaborations with Beam Therapeutics to advance delivery technologies targeting cardiovascular issues and with Verily for developing gene editing delivery vehicles. Formerly known as Endcadia, Verve Therapeutics rebranded in September 2019 to reflect its commitment to addressing heart disease through advanced genetic solutions.
Billtrust develops a payment cycle management platform designed to automate every step in the invoice-to-cash process. Its platform accelerates cash flow by automating invoice delivery, invoice payment, and cash application for remarkable cost savings, ease-of-use, and improved customer satisfaction rates, enabling businesses and corporate clients to improve operational efficiency. The company was founded in 2001 and is headquartered in Lawrenceville, New Jersey.
Affinivax, Inc. is a biotechnology company based in Lexington, Massachusetts, that specializes in developing vaccines using its innovative Multiple Antigen Presenting System (MAPS) technology. This approach allows for the combination of protective polysaccharides and proteins in a single vaccine, aiming to enhance the immune response against various infectious diseases. Affinivax focuses on a range of pathogens, including Streptococcus pneumoniae, which poses significant health risks to both children and adults. The company seeks to create vaccines that provide broader disease coverage and address infectious diseases lacking effective immunization strategies. Founded in 2014, Affinivax benefits from insights provided by leading experts in infectious diseases and vaccines, and it has secured support from the Bill & Melinda Gates Foundation, along with exclusive licensing rights from Boston Children’s Hospital for its MAPS technology.
Scorpion Therapeutics, Inc. is a biotechnology company based in Boston, Massachusetts, focused on developing advanced precision oncology therapies for cancer treatment. Founded in 2020, the company aims to enhance the accessibility and effectiveness of precision medicine for cancer patients. Scorpion Therapeutics specializes in creating drugs in three primary areas: therapies targeting known oncogenes, agents for currently undruggable cancer targets, and innovative drugs for new targets. By integrating state-of-the-art technologies in target discovery, medicinal chemistry, and translational medicine, the company is committed to delivering next-generation precision oncology solutions. Its experienced leadership team is dedicated to employing a tailored approach to efficiently advance the field of precision cancer treatment.
Porch.com, Inc. operates an online platform that connects homeowners with local home repair services. The company also facilitates customers to arrange set-up and installation for purchased goods through overstock e-commerce platform. In addition, it offers Service Attach, a tool that enables overstock customers to add installation or assembly services to online shopping carts. Porch.com, Inc. has a strategic partnership with Cinch Home Services Inc. The company as incorporated in 2011 and is based in Seattle, Washington.
Creditas is a financial technology company based in São Paulo, Brazil, specializing in secured consumer loans. Founded by Sergio Furio, the company operates a digital platform that leverages credit scoring and borrower assets, such as homes and automobiles, as collateral to provide loans. This approach allows Creditas to offer affordable lending solutions by partnering with traditional financial institutions and utilizing investor-backed resources. The platform is designed to enable borrowers to repay their loans in manageable installments, thereby making financing more accessible.
Cityblock Health is a healthcare provider focused on delivering primary care, behavioral health, and virtual care services to lower-income communities. Established in 2017 and based in Brooklyn, New York, Cityblock leverages technology to offer personalized, prevention-oriented care for urban residents with complex health needs. The company's platform facilitates access to preventive visits, mental health services, and social support programs. Additionally, Cityblock offers a communication tool called Commons, which enhances information sharing and task management among members and care teams. During the COVID-19 pandemic, Cityblock developed a model to identify individuals at high risk, highlighting its commitment to addressing urgent health challenges. By prioritizing upstream investments in health and social care, Cityblock aims to improve health outcomes while reducing overall costs.
Edgewise Therapeutics is a clinical-stage biopharmaceutical company based in Boulder, Colorado, specializing in the development of small molecule therapies for severe musculoskeletal diseases. Founded in 2017, the company leverages its expertise in skeletal muscle physiology to create innovative treatments for genetically defined muscle disorders, including Duchenne, Becker, and limb girdle muscular dystrophies. Edgewise Therapeutics employs a precision medicine platform to identify and target key muscle proteins and modulators, aiming to address the underlying causes of these conditions. Additionally, the company has established a state-of-the-art research facility to enhance its capabilities in understanding muscle adaptation and injury related to disease.
Current is a leading U.S. challenger bank built to meet the needs of people with unique lives who have been overlooked by the traditional banking industry. Our proprietary Current Core technology allows us to provide premium banking services for everyone, regardless of age or income, and improve the financial outcomes of our members without overdraft fees, minimum balance requirements, or hidden fees. We give members up to two days faster direct deposit paychecks, free overdrafts up to $100 with Overdrive™ , points on purchases redeemable for cash back, access to 55,000 free ATMs worldwide as well as 24/7 member support 365 days a year.
LianBio’s mission is to catalyze the development and accelerate availability of paradigm-shifting medicines to patients in China and major Asian markets through partnerships that provide access to the best science-driven therapeutic discoveries. LianBio collaborates with world-class partners across a diverse array of therapeutic and geographic areas to build out a pipeline based on disease relevance and the ability to impact patients with transformative mechanisms and precision-based therapeutics.
Gracell Biotechnologies Inc. is a clinical-stage biopharmaceutical company based in Shanghai, China, focused on discovering and developing innovative cell therapies for cancer treatment. The company's lead product candidates include GC012F, a dual-targeted CAR-T therapy for multiple myeloma currently in Phase I trials; GC019F, which targets adult B cell acute lymphoblastic leukemia and is also in Phase I trials; and GC007F, aimed at B cell non-Hodgkin’s lymphoma, also in Phase I. Additionally, Gracell is developing GC027, a CAR-T candidate targeting adult T cell acute lymphoblastic leukemia, and GC007g, an allogeneic CAR-T therapy for relapsed or refractory B-ALL, both in Phase I trials. Beyond these, Gracell has a pipeline of earlier-stage product candidates targeting various cancers, including ovarian and breast cancer. Founded in 2017, Gracell Biotechnologies is committed to advancing cellular therapeutics to improve patient outcomes in hematological malignancies and solid tumors.
Scopely, Inc. is a global interactive entertainment company specializing in mobile and tablet games for casual and core gamers. Founded in 2011 and headquartered in Culver City, California, Scopely creates and publishes a diverse range of immersive gaming experiences based on both original and established franchises. Notable titles in its portfolio include Star Trek Fleet Command, Looney Tunes World of Mayhem, WWE Champions, The Walking Dead: Road To Survival, YAHTZEE With Buddies, and Wheel of Fortune: Free Play. The company has garnered recognition for its rapid growth and innovation, achieving over $1 billion in lifetime revenue. With operations in various international locations, including Los Angeles, Barcelona, Dublin, and Tokyo, Scopely is supported by a skilled team and a proprietary technology platform that enhances its extensive portfolio of games.
Lordstown Motors Corporation is an American automobile manufacturer of electric vehicles.Lordstown Motors is completing the engineering and development of the first full-electric pickup truck.
Nuvation Bio Inc., a biopharmaceutical company, focuses on the development of therapies for oncology. Its portfolio includes various oncology programs with multiple drug development candidates. Nuvation Bio Inc.was formerly known as RePharmation Inc. and changed its name to Nuvation Bio Inc. in April 2019. The company was founded in 2018 and is based in New York, New York with an additional office in San Francisco, California.
Olema Oncology is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of therapies for women's cancers, particularly focusing on estrogen receptor-positive breast cancer. The company's lead candidate, OP-1250, is an estrogen receptor antagonist and selective degrader, currently undergoing Phase 1/2 clinical trials for the treatment of metastatic or locally advanced, estrogen receptor-positive, and human epidermal growth factor receptor 2-negative breast cancer. Olema Oncology aims to innovate targeted therapies by leveraging its expertise in endocrine-driven cancers and mechanisms of acquired resistance. The company seeks to enhance treatment options for both pre- and post-menopausal women with breast cancer, striving to transform the standard of care with more effective and convenient therapies. Founded in 2006 and headquartered in San Francisco, California, Olema was previously known as CombiThera, Inc. and rebranded in 2009.
Novellus is a biotechnology company working to develop engineered cellular medicines. The company uses its non-immunogenic mRNA molecules to reprogram and gene-edit cells safely, and with high efficiency. They engineer precision medicines for patient segments and select from its technology toolbox for in vivo, ex vivo, allogeneic and autologous delivery. Novellus platform enables the high-level expression of gene-editing and cell-reprogramming proteins for high-specificity gene repair and both autologous and allogeneic cell therapies. The company is advancing its lead program, a breakthrough therapy for a rare dermatologic disease, through pre-clinical studies. Novellus was founded in 2015 and is headquartered in Cambridge, Massachusetts, United States.
Attentive Mobile, Inc. is a personalized mobile messaging platform that enables companies to effectively acquire, retain, and engage with their mobile audiences. Founded in 2016 and headquartered in New York, the company serves a diverse range of industries, including e-commerce, retail, food and beverage, travel, hospitality, entertainment, media, publishing, education, and non-profit sectors. By leveraging real-time behavioral data, Attentive automates the delivery of tailored text messages throughout the customer lifecycle, which includes product recommendations, special promotions, payment notifications, and real-time customer service. With over 2,000 clients, including well-known brands like Sephora and Urban Outfitters, Attentive has demonstrated significant effectiveness, achieving impressive metrics such as over 30% click-through rates and more than 25 times return on investment.
Affirm is a financial technology company that offers installment loans to consumers at the point of sale, allowing them to make purchases from online merchants and pay for them in fixed monthly installments. Founded in 2012 and headquartered in San Francisco, with an additional office in Chicago, Affirm aims to provide transparent financial products that empower consumers and enhance their buying experience. Customers can select Affirm as a payment method at checkout, complete a real-time application, and choose a payment plan that aligns with their budget. The service stands out by offering upfront pricing with no hidden fees or compounding interest, unlike traditional credit options. Affirm partners with over 2,000 merchants across various sectors, including retail, travel, and electronics, to provide consumers with a flexible alternative to credit cards. Loans are facilitated through a partnership with Cross River Bank, ensuring a reliable financing option for users.
E-Scape Bio, Inc. is a clinical-stage biopharmaceutical company focused on the discovery and development of small molecule therapies for neurodegenerative diseases. Established in 2015 and headquartered in South San Francisco, California, the company aims to improve the lives of patients suffering from conditions such as Alzheimer’s disease, Parkinson’s disease, and sphingolipid storage disorders. E-Scape Bio is advancing a pipeline of therapeutics that target specific genetic drivers of these diseases, including ESB1609, a small molecule S1P5 receptor agonist for CNS lysosomal storage disorders, and ESB5070, a kinase inhibitor designed for Parkinson’s disease patients with the LRRK2 G2019S variant. Additionally, the company is developing a program targeting ApoE4 in Alzheimer’s disease, emphasizing its commitment to precision medicine in treating genetically defined subpopulations.
Patreon Inc. operates a membership platform designed to help content creators and artists fund their work. Founded in 2013 and based in San Francisco, California, Patreon.com facilitates connections between users and provides access to various types of content, including videos, photographs, artwork, audio clips, and more. The platform allows patrons to pledge support to their favorite creators on a recurring basis, thereby empowering a new generation of artists to earn a living from their passions. By enabling direct financial support from fans, Patreon fosters a sustainable ecosystem for creative individuals to thrive.
Skillz operates as a marketplace platform that connects mobile gamers, allowing them to discover and compete in various games against players globally. The company supports game developers in creating lucrative franchises by integrating social competition into their offerings. Utilizing patented technology, Skillz has facilitated over 2 billion tournament entries for approximately 30 million players worldwide, distributing over $60 million in prizes monthly. Notable games on its platform include Dominoes Gold, Blackout Bingo, 21 Blitz, and Solitaire Cube. Skillz primarily generates revenue through its eSports gaming platform, which enables developers to monetize their content via multiplayer competitions. The company's operations are mainly concentrated in the United States, with additional revenue from regions such as Israel, China, and Malta. Skillz has garnered recognition in the industry, being listed among Fast Company's Most Innovative Companies and CNBC's Disruptor 50, among other accolades.
Synthego is a genome engineering company that enables the acceleration of life science research and development in the pursuit of improved human health.
The company leverages machine learning, automation, and gene editing to build platforms for science at scale. With its foundations in engineering disciplines, the company’s full-stack platform vertically integrates proprietary hardware, software, bioinformatics, chemistries, and molecular biology to advance both basic research and therapeutic development programs.
By providing both commercial and academic researchers and therapeutic developers with unprecedented access to cutting-edge genome engineering, Synthego is at the forefront of innovation, accelerating the development of truly engineered biology.
The company was founded in 2012 and is based in Redwood City, California.
Dyne Therapeutics, Inc., a muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It develops various programs for myotonic dystrophy type 1, duchenne muscular dystrophy, and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapies. The company was founded in 2017 and is based in Waltham, Massachusetts.
PMV Pharma is developing first-in-class p53 and p53 pathway modulators for the treatment of cancer. Bringing together leaders in the field to utilize over three decades of p53 biology, PMV Pharma combines unique biological understanding with pharmaceutical development focus.
Olema Oncology is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of therapies for women's cancers, particularly focusing on estrogen receptor-positive breast cancer. The company's lead candidate, OP-1250, is an estrogen receptor antagonist and selective degrader, currently undergoing Phase 1/2 clinical trials for the treatment of metastatic or locally advanced, estrogen receptor-positive, and human epidermal growth factor receptor 2-negative breast cancer. Olema Oncology aims to innovate targeted therapies by leveraging its expertise in endocrine-driven cancers and mechanisms of acquired resistance. The company seeks to enhance treatment options for both pre- and post-menopausal women with breast cancer, striving to transform the standard of care with more effective and convenient therapies. Founded in 2006 and headquartered in San Francisco, California, Olema was previously known as CombiThera, Inc. and rebranded in 2009.
VelosBio, Inc. is a clinical-stage biopharmaceutical company based in San Diego, California, focused on developing innovative antibody-drug conjugates (ADCs) to treat hematological cancers and solid tumors. The company specializes in therapies targeting receptor tyrosine kinase-like orphan receptor 1 (ROR1), a cell-surface protein commonly found in various tumors but absent in normal tissues, making it a promising target for cancer treatment. Its lead product, VLS-101, is designed as a ROR1-directed ADC aimed at patients with both hematologic and solid tumor malignancies. Founded in 2017, VelosBio has demonstrated positive preclinical results for its ROR1-directed therapeutics, paving the way for potential use in monotherapy or in combination with other treatments across a wide range of cancers. As of late 2020, VelosBio operates as a subsidiary of Merck & Co., Inc.
Goldfinch Bio, Inc. is a clinical-stage biotechnology company dedicated to discovering and developing precision therapies for kidney diseases. The company focuses on researching and commercializing treatments for conditions such as focal segmental glomerulosclerosis, diabetic nephropathy, and polycystic kidney disease. Notable programs include GFB-887, a selective inhibitor of the TRPC5 channel, and GFB-024, a cannabinoid receptor 1 inverse agonist. Goldfinch Bio is also developing the Kidney Genome Atlas, a genomic registry aimed at identifying new disease targets and biomarkers, and utilizes a biology platform that leverages stem cell science to create human organoid models for target validation. Founded in 2016 and based in Cambridge, Massachusetts, Goldfinch Bio has established a strategic collaboration with Gilead Sciences to enhance its capabilities in kidney disease therapy development.
Freeline Therapeutics is a clinical-stage biotechnology company focused on developing liver-directed gene therapies for bleeding disorders and other diseases. Based in Stevenage, United Kingdom, Freeline's lead product candidate, FLT180a, is undergoing Phase 1/2 clinical trials aimed at treating moderate to severe hemophilia B. The company's pipeline also includes FLT190, which is in dose-escalating Phase 1/2 trials for Fabry disease, FLT201 for type 1 Gaucher disease, and FLT210 for hemophilia A. Freeline utilizes a next-generation proprietary adeno-associated virus (AAV) vector platform, enhancing its potential for systemic gene therapy applications. Since its founding in 2015, the company has been dedicated to advancing innovative treatments in the field of gene therapy.
Prove provides a phone-centric identity platform designed to enhance security and reduce fraud through the use of phone numbers. With over 1 billion identity tokens under management, Prove assists more than 1,000 companies and over 500 banks, including leading financial institutions, in securing their customer onboarding, digital services, and payment processes. The company offers two primary solutions: Prove Pre-fill™, which streamlines the onboarding process by authenticating consumer identities and auto-filling verified data, and Fonebook™, which provides a comprehensive identity authentication platform to manage customer phone numbers and create a unified customer view across various channels. Additionally, Prove offers multi-factor authentication options, including SMS and voice OTPs, instant link authentication, mobile authentication through cellular networks, voice biometrics, and app-based push authentication. These features enable secure transactions and enhance the overall customer experience across mobile, desktop, and in-store environments. Prove's services are available in 195 countries, underscoring its global reach in identity verification and fraud mitigation.
Verve Therapeutics, Inc. is a biotechnology company focused on developing innovative therapies aimed at editing the adult human genome to reduce the risk of coronary artery disease, a leading cause of death globally. Founded in 2018 and headquartered in Cambridge, Massachusetts, with a research facility in Philadelphia, the company leverages human genetic analysis and gene-editing technologies to create treatments that offer lifelong protection from this condition. Verve has established strategic alliances, including collaborations with Beam Therapeutics to advance delivery technologies targeting cardiovascular issues and with Verily for developing gene editing delivery vehicles. Formerly known as Endcadia, Verve Therapeutics rebranded in September 2019 to reflect its commitment to addressing heart disease through advanced genetic solutions.
Juspay is a developer of an online platform designed to be used for mobile-based payments. The company's online platform is a SaaS layer on top of payment gateways to simplify integration, improve robustness and ease the management of diverse and rapidly evolving payment options, enabling users to make electronic transactions securely and efficiently.
Kymera Therapeutics is a biopharmaceutical company based in Watertown, Massachusetts, established in 2015. It specializes in targeted protein degradation, developing innovative small molecule therapeutics that selectively degrade proteins associated with various diseases by utilizing the body's natural protein degradation mechanisms. The company is advancing several therapeutic programs, including the IRAK4 program aimed at treating immunology-inflammation diseases such as hidradenitis suppurativa, atopic dermatitis, and rheumatoid arthritis. Additionally, it is developing the IRAKIMiD program for MYD88-mutated diffuse large B cell lymphoma and the STAT3 program for hematologic malignancies and solid tumors, as well as autoimmune diseases. Through its proprietary predictive modeling platform, Kymera Therapeutics seeks to accelerate drug discovery and address previously untreatable conditions.
Nurix Therapeutics is a biopharmaceutical company dedicated to the discovery and development of small molecule therapies aimed at treating cancer and immune disorders. The company focuses on innovative approaches to modulate cellular protein levels, utilizing its expertise in the ubiquitin-proteasome system. Its lead preclinical candidates include NX-2127, an orally available Bruton’s tyrosine kinase (BTK) degrader targeting relapsed or refractory B-cell malignancies, and NX-1607, a Casitas B-lineage lymphoma proto-oncogene-B (CBL-B) inhibitor for immuno-oncology applications. Nurix also offers DELigase, a discovery platform that identifies and advances novel drug candidates by targeting E3 ligases, which play a crucial role in protein regulation. Founded in 2009 and based in San Francisco, the company has established strategic collaborations with major pharmaceutical firms, enhancing its potential in the competitive biopharmaceutical landscape.