Y Combinator

Adaptyv Biosystems developing a protein engineering platform using cell-free synthetic biology and nanofluidics.

Benchling, Inc. is a developer of a cloud-based informatics platform tailored for life sciences research and development. The platform encompasses a range of integrated applications that enable scientists to design, share, and document experiments efficiently. Key offerings include an electronic lab notebook for experiment documentation, a biological registration system for managing inventory like plasmids and antibodies, and analytical tools for visualizing and collaborating on structured data. Benchling's software supports cutting-edge research techniques such as CRISPR and CAR-T immunotherapy, facilitating advancements in biotherapeutics, biofuels, and biomaterials. The company's solutions are utilized by researchers in biotech and pharmaceutical companies, as well as academic and government labs, streamlining workflows and enhancing collaboration across various research projects. Founded in 2012, Benchling is headquartered in San Francisco, California.

Cambridge Glycoscience is a biotechnology company based in London, United Kingdom, founded in 2017. The company specializes in developing sugar-free ingredients for the food industry, focusing on creating natural food components derived from agricultural resources. Their innovative products enable food manufacturers to reduce sugar content, enhance fiber levels, and improve gut health-promoting qualities in food items. By leveraging biotechnology, Cambridge Glycoscience aims to support healthier eating options and contribute to the evolving landscape of food production.

FitHub operates an e-commerce marketplace focused on the fitness and wellness industry, providing a diverse selection of healthy foods, supplements, and personal care products. The company aims to improve consumer habits through scientifically proven technologies and is dedicated to addressing major health issues related to nutrition, exercise, and lifestyle. By offering eco-friendly sourced products, FitHub enables consumers to adopt healthier lifestyles and cultivate positive habits, positioning itself as a comprehensive destination for those seeking to enhance their well-being.

Known Medicine is looking to take the experimentation of how tumors respond to cancer drugs out of the patient’s body and into the lab. The startup breaks down tumor samples into micro tumors, which they treat separately inside specialized micro-environments with different methods and see what works best.

Adaptyv Biosystems developing a protein engineering platform using cell-free synthetic biology and nanofluidics.

Pipe | bio builds bioinformatics solutions to help optimize development of antibodies and antibody-like-therapeutics.

Orbillion Bio, Inc., a food-tech company, develops cultured meat products using a small tissue sample from heritage cattle breeds. It develops premium cell-based meat products from heritage cell lines that are directly sourced from farmers. The company was incorporated in 2019 and is based in Fremont, California.

LiliumX discovers new bispecific antibodies against cancer by utilizing a protein technology platform to facilitate the scalable discovery of first-in-class bispecific biologics.

Pipe | bio builds bioinformatics solutions to help optimize development of antibodies and antibody-like-therapeutics.

FitHub operates an e-commerce marketplace focused on the fitness and wellness industry, providing a diverse selection of healthy foods, supplements, and personal care products. The company aims to improve consumer habits through scientifically proven technologies and is dedicated to addressing major health issues related to nutrition, exercise, and lifestyle. By offering eco-friendly sourced products, FitHub enables consumers to adopt healthier lifestyles and cultivate positive habits, positioning itself as a comprehensive destination for those seeking to enhance their well-being.

Cambridge Glycoscience is a biotechnology company based in London, United Kingdom, founded in 2017. The company specializes in developing sugar-free ingredients for the food industry, focusing on creating natural food components derived from agricultural resources. Their innovative products enable food manufacturers to reduce sugar content, enhance fiber levels, and improve gut health-promoting qualities in food items. By leveraging biotechnology, Cambridge Glycoscience aims to support healthier eating options and contribute to the evolving landscape of food production.

Future Fields is a Canadian company dedicated to advancing cellular agriculture by creating accessible consumer products. The company specializes in developing cost-effective and serum-free growth media essential for the production of cultured meat. Additionally, Future Fields focuses on insect-based recombinant protein to enhance sustainability in protein production. By producing vital growth components for cell culture, the company aims to reduce the environmental impact of agriculture while maximizing social benefits. Through these innovations, Future Fields seeks to enable the agriculture industry to produce cell-based foods in a more efficient and sustainable manner.

Atom Bioworks specializes in developing a pattern-recognition-enabled sensing and therapeutics platform aimed at enhancing medical applications for the early diagnosis and treatment of infectious diseases and cancer. The company's innovative platform leverages computational biology, quantum chemistry, software, and machine learning to identify diseased surface protein patterns. By creating corresponding pattern-matching constructs, Atom Bioworks provides researchers with advanced nano-pattern recognition capabilities, ultimately facilitating improved diagnostic and therapeutic strategies in the medical field.

FitHub operates an e-commerce marketplace focused on the fitness and wellness industry, providing a diverse selection of healthy foods, supplements, and personal care products. The company aims to improve consumer habits through scientifically proven technologies and is dedicated to addressing major health issues related to nutrition, exercise, and lifestyle. By offering eco-friendly sourced products, FitHub enables consumers to adopt healthier lifestyles and cultivate positive habits, positioning itself as a comprehensive destination for those seeking to enhance their well-being.

Hannah Life Technologies Pte. Ltd., founded in 2019 and based in Singapore, specializes in designing and developing innovative devices aimed at improving conception chances for couples during intercourse. The company seeks to transform the infertility treatment landscape by creating groundbreaking and safe fertility products that address significant unmet needs in this field. Guided by a Scientific Advisory Board composed of leading fertility clinicians, Hannah Life Technologies is committed to advancing solutions that enhance reproductive health and support individuals facing infertility challenges.

Tappity, Inc. designs and develops an education science app that provides fun interactive lessons on science topics. The company's application teaches science topics with fun, experiments, stories, and games to children of age group 4 to 10 years. Tappity, Inc. was founded in 2018 and is based in Palo Alto, California.

Future Fields is a Canadian company dedicated to advancing cellular agriculture by creating accessible consumer products. The company specializes in developing cost-effective and serum-free growth media essential for the production of cultured meat. Additionally, Future Fields focuses on insect-based recombinant protein to enhance sustainability in protein production. By producing vital growth components for cell culture, the company aims to reduce the environmental impact of agriculture while maximizing social benefits. Through these innovations, Future Fields seeks to enable the agriculture industry to produce cell-based foods in a more efficient and sustainable manner.

Known Medicine is looking to take the experimentation of how tumors respond to cancer drugs out of the patient’s body and into the lab. The startup breaks down tumor samples into micro tumors, which they treat separately inside specialized micro-environments with different methods and see what works best.

Lambda Inc., doing business as Lambda School, provides online coding and computer science education training services in the United States. It provides training in computer science, software engineering, neural networks, artificial intelligence, and machine learning. The company also offers courses in JavaScript and website development. It provides online and live training sessions with instruction, hands-on projects, pair programming, and code reviews from instructors. The company was founded in 2016 and is based in San Francisco, California.

54gene develops a pan-African biobank to identify new drug targets, and develop diagnostics and treatments for diseases. The company targets multiple disease states, including cancer, cardiovascular disease, and neuro-degenerative disease. It also provides genetic testing and molecular diagnostics services. The company was founded in 2019 and is based in San Francisco, California with an additional offices in Lagos, Nigeria.

Operator is building a low-code platform that makes it easy to build business applications. With Operator, analysts can build software solutions to common problems and bottlenecks without worrying about managing data or setting up integrations.

Abalone Bio, Inc. is a biotechnology company focused on developing antibody drugs for various medical conditions, including pain, inflammatory diseases, rare cancers, and rare kidney diseases. Founded in 2017 and based in Richmond, California, the company aims to create treatments for peripheral neuropathy. Abalone Bio employs advanced techniques such as yeast cell libraries to generate billions of antibody variants, which can either activate or inhibit specific drug targets. Additionally, the company utilizes gene sequencing, machine learning, and synthetic biology to produce recombinant protein versions of its antibodies and to validate their efficacy through human cell assays. This innovative approach allows Abalone Bio to address rare diseases with distinct mechanisms of action.

Ochre Bio develops genomic medicines to rejuvenate donors' livers before transplant, so that everyone who needs a new liver gets one. They use genomics to find and shut down over-active genes driving disease and then go directly to testing therapies in discarded donor livers that keep alive outside of the body. Ochre Bio is within the heart of Oxford’s biotech innovation hub. Their scientific roots can be traced back to over 15 years leading liver genomics research and experience in bringing advanced therapies to market.

Culture Biosciences, founded in 2016 and headquartered in San Francisco, California, specializes in developing automated bioreactors and tools for fermentation. The company provides a digital bio-manufacturing platform that allows biotech companies to optimize their manufacturing processes, enabling them to bring products to market more efficiently. By utilizing robotic sample handling and cloud-based data monitoring and analysis, Culture Biosciences helps scientists run, monitor, and analyze bioreactors more quickly than traditional methods. This innovative approach supports the biotechnology sector in enhancing productivity and streamlining workflows.

Sequence Bio is a data-driven biotechnology company in Newfoundland and Labrador. We're leading the NL Genome Project, a large-scale genomics project studying Newfoundland’s unique genetic makeup by combining multi-omic data with longitudinal health records to improve how we understand, treat, and prevent disease. Our goal is to use data and new computational approaches to enable better healthcare and transform drug discovery.

Gen1E Lifesciences is a developer of a platform designed to accelerate cures for inflammatory and age-related diseases.The company's services include a pipeline of preclinical stage products that includes a P38 kinase inhibitor for the treatment of various inflammatory diseases, enabling medical researchers to optimize existing regulatory incentives, reduce the required R&D time and cost, truncate the time to exit and improve the success rate in receiving FDA approval and commercial success.

Benchling, Inc. is a developer of a cloud-based informatics platform tailored for life sciences research and development. The platform encompasses a range of integrated applications that enable scientists to design, share, and document experiments efficiently. Key offerings include an electronic lab notebook for experiment documentation, a biological registration system for managing inventory like plasmids and antibodies, and analytical tools for visualizing and collaborating on structured data. Benchling's software supports cutting-edge research techniques such as CRISPR and CAR-T immunotherapy, facilitating advancements in biotherapeutics, biofuels, and biomaterials. The company's solutions are utilized by researchers in biotech and pharmaceutical companies, as well as academic and government labs, streamlining workflows and enhancing collaboration across various research projects. Founded in 2012, Benchling is headquartered in San Francisco, California.

54gene develops a pan-African biobank to identify new drug targets, and develop diagnostics and treatments for diseases. The company targets multiple disease states, including cancer, cardiovascular disease, and neuro-degenerative disease. It also provides genetic testing and molecular diagnostics services. The company was founded in 2019 and is based in San Francisco, California with an additional offices in Lagos, Nigeria.

Sequence Bio is a data-driven biotechnology company in Newfoundland and Labrador. We're leading the NL Genome Project, a large-scale genomics project studying Newfoundland’s unique genetic makeup by combining multi-omic data with longitudinal health records to improve how we understand, treat, and prevent disease. Our goal is to use data and new computational approaches to enable better healthcare and transform drug discovery.

Volta Labs, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on engineering and developing tools for biological automation. Founded in 2018, the company specializes in creating scalable automation solutions for genetic engineering, aiming to enhance efficiency and precision in biological research and applications.

54gene develops a pan-African biobank to identify new drug targets, and develop diagnostics and treatments for diseases. The company targets multiple disease states, including cancer, cardiovascular disease, and neuro-degenerative disease. It also provides genetic testing and molecular diagnostics services. The company was founded in 2019 and is based in San Francisco, California with an additional offices in Lagos, Nigeria.

Synova Life Sciences is developing a novel non-enzymatic device to obtain stem cells from adipose tissue for medical research and therapy. They help physicians and patients harvest autologous stem cells and use their regenerative ability to enhance the quality of life. Synova Life Sciences is the winner of Cal State Fullerton Business Plan Competition 2013, MD&M West "Shark Tank" 2015, TriTech Funding the Big Idea 2015 and was the First Runner Up at TCVN Survivor 8. Synova Life Sciences was founded in 2013.

Lambda Inc., doing business as Lambda School, provides online coding and computer science education training services in the United States. It provides training in computer science, software engineering, neural networks, artificial intelligence, and machine learning. The company also offers courses in JavaScript and website development. It provides online and live training sessions with instruction, hands-on projects, pair programming, and code reviews from instructors. The company was founded in 2016 and is based in San Francisco, California.

Lambda Inc., doing business as Lambda School, provides online coding and computer science education training services in the United States. It provides training in computer science, software engineering, neural networks, artificial intelligence, and machine learning. The company also offers courses in JavaScript and website development. It provides online and live training sessions with instruction, hands-on projects, pair programming, and code reviews from instructors. The company was founded in 2016 and is based in San Francisco, California.

Dorian Therapeutics is focused on developing innovative therapeutics aimed at combating cellular aging and enhancing medical conditions. The company specializes in creating treatments that inhibit the aging process at the cellular level, particularly targeting T cells to improve their function, fitness, and longevity. By rejuvenating these cells, Dorian Therapeutics enables medical practitioners to restore youthful characteristics and regenerative capabilities in patients, ultimately contributing to improved health outcomes.

Cambridge Glycoscience is a biotechnology company based in London, United Kingdom, founded in 2017. The company specializes in developing sugar-free ingredients for the food industry, focusing on creating natural food components derived from agricultural resources. Their innovative products enable food manufacturers to reduce sugar content, enhance fiber levels, and improve gut health-promoting qualities in food items. By leveraging biotechnology, Cambridge Glycoscience aims to support healthier eating options and contribute to the evolving landscape of food production.

Data Driven Bioscience is a company based in Durham, North Carolina, that specializes in providing integrated kits and software designed for cancer diagnosis. Their products enable clinical laboratories to utilize genomics in the diagnosis and treatment of cancer. The kits are equipped to connect with machine learning software and a comprehensive database of cancer cases, allowing for the generation of detailed molecular reports for individual tumors. This innovative approach aims to enhance the accuracy and effectiveness of cancer diagnostics, facilitating better treatment decisions for patients.

64x Bio is a biotechnology company based in San Francisco, California, founded in 2017 by Alexis Rovner, George Church, Jeffrey Way, and Pamela Silver. The company specializes in designing microorganisms with enhanced properties to facilitate advanced applications in biomanufacturing, bioremediation, and health. By creating cells tailored for specific purposes, 64x Bio aims to enable innovative solutions that were previously unattainable in these fields.

Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production. The company's throughput screening and strain construction facilitate the rapid optimization of pathways to convert cheap and renewable feedstock to high-value chemicals. Founded in 2011, Lygos is headquartered in Berkeley, California.

Mind emulation enables your mind to continue to live on after your body has died. Their mission is to fund and conduct scientific research in order to accelerate their path toward human mind emulation.

Lambda Inc., doing business as Lambda School, provides online coding and computer science education training services in the United States. It provides training in computer science, software engineering, neural networks, artificial intelligence, and machine learning. The company also offers courses in JavaScript and website development. It provides online and live training sessions with instruction, hands-on projects, pair programming, and code reviews from instructors. The company was founded in 2016 and is based in San Francisco, California.

Culture Biosciences, founded in 2016 and headquartered in San Francisco, California, specializes in developing automated bioreactors and tools for fermentation. The company provides a digital bio-manufacturing platform that allows biotech companies to optimize their manufacturing processes, enabling them to bring products to market more efficiently. By utilizing robotic sample handling and cloud-based data monitoring and analysis, Culture Biosciences helps scientists run, monitor, and analyze bioreactors more quickly than traditional methods. This innovative approach supports the biotechnology sector in enhancing productivity and streamlining workflows.

Avro Life Science is a Canadian company focused on developing transdermal drug delivery systems, specifically medicated skin patches designed for the pediatric and elderly populations. Utilizing a novel biopolymer as a platform, Avro's technology enables passive delivery of small molecules and drugs directly into the bloodstream, allowing for a slow-release mechanism. This innovative approach aims to enhance medication accessibility while minimizing the impact on the liver, ultimately improving health outcomes and quality of life for its patients.

Sixfold Bioscience is a preclinical-stage biotech company that engineers targeted therapeutic delivery systems. Their programmable oligonucleotide delivery systems are able to deliver gene therapy molecules exclusively to diseased cells. It also provides a solution to the drug delivery challenge, bringing cures for genetically-driven diseases to patients. Sixfold Bioscience was founded on 2017 and is headquartered in London.

Ginkgo Bioworks, founded in 2008 and based in Boston, Massachusetts, specializes in biological engineering by designing, developing, and licensing custom microbes and organisms. The company focuses on discovering and producing a variety of molecules for applications in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, Ginkgo Bioworks offers probiotic bacteria aimed at protecting against harmful infections and creates libraries of molecules for various uses. Its market reach includes sectors such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Forever Labs, Inc. is a biomedical research company that cryogenically freeze the stem cells, allowing them to use those cells to fight their age-related diseases in the future. The company is based in Ann Arbor, Michigan.

Life Bot is the only voice app you need to complete daily activities with your voice. Life Bot is a team of voice designers and developers making it their mission to build the best voice apps for Alexa and Google home.

Lambda Inc., doing business as Lambda School, provides online coding and computer science education training services in the United States. It provides training in computer science, software engineering, neural networks, artificial intelligence, and machine learning. The company also offers courses in JavaScript and website development. It provides online and live training sessions with instruction, hands-on projects, pair programming, and code reviews from instructors. The company was founded in 2016 and is based in San Francisco, California.

TL Biolabs Corp. is a biotechnology company based in Santa Clara, California, that specializes in automated genomic testing for livestock. Established in 2016, the company focuses on providing cost-effective genomic tests specifically for beef and dairy cattle. In addition to its testing services, TL Biolabs offers complimentary software designed to deliver actionable results, enhancing decision-making for livestock management.

Nephrogen is a biotechnology company dedicated to developing novel diagnostics and research tools for various life threatening diseases.

Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production. The company's throughput screening and strain construction facilitate the rapid optimization of pathways to convert cheap and renewable feedstock to high-value chemicals. Founded in 2011, Lygos is headquartered in Berkeley, California.

Luminostics, Inc. develops a smartphone-based adaptor to access molecular-level health information through 15-minute DIY disease testing. It serves healthcare professionals and consumers. The company was incorporated in 2015 and is based in Houston, Texas.

An Adaptive Learning Platform for Science and Social Studies. Rocketlit serves adaptive reading from the 3rd-12th grade reading levels to students in Science and Social Studies, to help both struggling readers and challenge advanced students.

Ginkgo Bioworks, founded in 2008 and based in Boston, Massachusetts, specializes in biological engineering by designing, developing, and licensing custom microbes and organisms. The company focuses on discovering and producing a variety of molecules for applications in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, Ginkgo Bioworks offers probiotic bacteria aimed at protecting against harmful infections and creates libraries of molecules for various uses. Its market reach includes sectors such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Lygos is providing biotechnology solutions for today’s renewable chemical challenges. They engineer microbes to convert sugars into high-value, industrial chemicals, targeting compounds where biological production is cost-advantaged over petrochemical production. The company's throughput screening and strain construction facilitate the rapid optimization of pathways to convert cheap and renewable feedstock to high-value chemicals. Founded in 2011, Lygos is headquartered in Berkeley, California.

Cryopreserving people's healthy young cells for use with future medical technologies.

Ginkgo Bioworks, founded in 2008 and based in Boston, Massachusetts, specializes in biological engineering by designing, developing, and licensing custom microbes and organisms. The company focuses on discovering and producing a variety of molecules for applications in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, Ginkgo Bioworks offers probiotic bacteria aimed at protecting against harmful infections and creates libraries of molecules for various uses. Its market reach includes sectors such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

BuildScience is a team of University of Waterloo Engineering alumni with a passion for cutting-edge technology. Having worked at Fortune 500 companies, startups and institutions, they understand that tackling the challenges faced by today's buildings requires a diverse team. Over the years they've gained extensive experience working with hardware, software and power systems. They’ve built data-driven analytics that shaped display technology, designed a meteorological station that landed on Mars, and improved electricity system reliability.

At 20n, They use algorithms to engineer microbes. Specifically, their algorithms engineer microbes to make chemicals. Like yeast produces alcohol during beer brewing, their engineered microbes will produce chemicals with therapeutic health and industrial biotech applications. The best illustration of this DARPA-backed technology is the bacteria They engineered to produce Paracetamol (also known as acetaminophen, and sold under the brand name Tylenol). Aside from this bacteria, there is no known natural way of producing acetaminophen. They are building data mining technology that will allow us to enable the bioproduction of a whole spectrum of valuable molecules. Below is the map of every chemical that can be made biologically, as discovered by 20n's algorithms.

Ginkgo Bioworks, founded in 2008 and based in Boston, Massachusetts, specializes in biological engineering by designing, developing, and licensing custom microbes and organisms. The company focuses on discovering and producing a variety of molecules for applications in flavors, sweeteners, cosmetic ingredients, crop treatments, and pharmaceuticals. Additionally, Ginkgo Bioworks offers probiotic bacteria aimed at protecting against harmful infections and creates libraries of molecules for various uses. Its market reach includes sectors such as cultured ingredients, carbon mitigation, probiotics, and natural product discovery.

Benchling, Inc. is a developer of a cloud-based informatics platform tailored for life sciences research and development. The platform encompasses a range of integrated applications that enable scientists to design, share, and document experiments efficiently. Key offerings include an electronic lab notebook for experiment documentation, a biological registration system for managing inventory like plasmids and antibodies, and analytical tools for visualizing and collaborating on structured data. Benchling's software supports cutting-edge research techniques such as CRISPR and CAR-T immunotherapy, facilitating advancements in biotherapeutics, biofuels, and biomaterials. The company's solutions are utilized by researchers in biotech and pharmaceutical companies, as well as academic and government labs, streamlining workflows and enhancing collaboration across various research projects. Founded in 2012, Benchling is headquartered in San Francisco, California.

Experiment Inc. operates as an online crowdfunding site that focuses on science. Its platform enables users to discover and experience new scientific discoveries in the areas of biology, ecology, paleontology, art and design, chemistry, physics, medicine, political science, social science, materials science, neuroscience, data science, economics, earth science, psychology, engineering, computer science, education, anthropology, and mathematics. Experiment Inc. was formerly known as Microryza Inc. and changed its name to Experiment Inc. in February 2014. The company was founded in 2010 and is based in San Francisco, California.

Science Exchange, Inc. operates an online marketplace designed to facilitate collaboration between researchers and scientific service providers, including academic and government laboratories. Founded in 2011 and headquartered in Palo Alto, California, the platform allows researchers to search for scientific services, compare pricing, and access quality testimonials, streamlining the procurement process. Additionally, Science Exchange offers an enterprise dynamic report tool that helps pharmaceutical and biotechnology companies track key performance indicators related to their outsourced research and development investments. By automating various collaborative tasks such as obtaining quotes, managing projects, and processing payments, the marketplace enhances R&D productivity while ensuring data security and regulatory compliance.