Y Combinator

Y Combinator is a startup accelerator based in Mountain View, California, founded in 2005. It has pioneered a new funding model for early-stage startups by investing a modest amount of capital, typically around $150,000, in a large number of companies twice a year. Over a three-month program, Y Combinator collaborates closely with these startups to prepare them for investor pitches and enhance their business strategies. Each funding cycle concludes with Demo Day, where startups present to an exclusive audience of investors. Y Combinator focuses on various sectors, including business software, education, healthcare, and financial technology, among others. In addition to initial funding, it offers ongoing support through its extensive alumni network. Since its inception, Y Combinator has funded over 630 startups, contributing significantly to the entrepreneurial ecosystem in Silicon Valley and beyond.

Gustaf Alstromer

Group Partner

Matt Bogrand

Associate, YC Continuity Fund

Timothy Brady

Partner

Craig R. Cannon

Director of Marketing

Adora Cheung

Partner

Nic Dardenne

Principal

Aaron Epstein

Group Partner

Brad Flora

Group Partner

Jared Friedman

Managing Director, Software and Group Partner

Aaron Harris

Partner

Carolynn Levy

Partner

Bradford (Brad) Lightcap

Associate, YC Continuity

Kat Manalac

Managing Partner

Eric Migicovsky

Partner

Kirsty Nathoo

Partner

Verena Prescher

Director of Finance

Geoff Ralston

president

Ali Rowghani

Managing Partner

Arnav Sahu

Principal

Michael Seibel

Managing Director

Harj Taggar

Partner

Past deals in Pharmaceuticals

Remedial Health

Seed Round in 2022
Remedial Health is a company focused on enhancing access to medicines for healthcare retail businesses, including large pharmacies and small chemist shops. By utilizing advanced technology, it develops a pharmacy operations and procurement management platform that facilitates direct ordering from manufacturers and registered distributors. This platform supports both large and small retailers in streamlining their dispensing and workflow management processes, ensuring just-in-time stock availability. Additionally, Remedial Health provides financing options and a diverse selection of inventory, thereby improving the efficiency and effectiveness of medicine procurement for its clients.

Neurolytic Healthcare Ltd.

Pre Seed Round in 2022
Neurolytic Healthcare Ltd. is a company based in Oxford, United Kingdom, specializing in the design, development, manufacturing, and delivery of digital and genomic-based diagnostic tools and medical devices aimed at treating migraine and related neurological disorders. Established in 2016, the company focuses on personalized medicine by integrating genetic and biomarker data to enhance diagnostic accuracy and assist clinicians in determining optimal treatment strategies. Its product offerings include a diagnostic support tool, a pharmacogenetic test, and a mobile application designed for predicting migraine events. Through these innovative solutions, Neurolytic Healthcare aims to improve the management and treatment of neurological conditions.

MedMe

Seed Round in 2022
MedMe Health is a patient care platform that assists pharmacists in scheduling, conducting, and tracking clinical services both virtually and on-site. The platform employs proprietary algorithms to streamline various medical services, including online scheduling, digital diagnosis, documentation filing, and automated follow-up appointments. By facilitating these processes, MedMe Health enables pharmacies to enhance their workflows, strengthen patient relationships, and diversify revenue opportunities within clinical services.

Parallel Bio

Pre Seed Round in 2021
Accelerating the discovery of immunotherapies

SFA Therapeutics

Convertible Note in 2021
SFA Therapeutics, Inc. is a development-stage biopharmaceutical company located in Jenkintown, Pennsylvania. The company specializes in the manufacturing of microbiome-derived metabolites to be used as therapeutic agents for chronic inflammatory diseases. By focusing on innovative approaches in drug development, SFA Therapeutics aims to address unmet medical needs in this area.

Ophelia

Series A in 2021
Ophelia Health, Inc. specializes in medication-assisted treatment for individuals struggling with opioid dependence. The company employs a digital platform to facilitate teleconferenced consultations between patients and licensed clinicians, allowing for convenient access to treatment from home. Ophelia provides not only prescription medications but also therapeutic support, aiming to eliminate the stigma often associated with traditional rehabilitation programs. Founded in 2019 and based in Philadelphia, Pennsylvania, Ophelia emphasizes a patient-centered approach that respects individual choices and prioritizes privacy. The organization combines expertise from various fields, including medicine and technology, to deliver evidence-based care and support to those seeking to overcome opioid addiction.

PipeBio

Seed Round in 2021
Pipe | bio builds bioinformatics solutions to help optimize development of antibodies and antibody-like-therapeutics.

MedMe

Seed Round in 2021
MedMe Health is a patient care platform that assists pharmacists in scheduling, conducting, and tracking clinical services both virtually and on-site. The platform employs proprietary algorithms to streamline various medical services, including online scheduling, digital diagnosis, documentation filing, and automated follow-up appointments. By facilitating these processes, MedMe Health enables pharmacies to enhance their workflows, strengthen patient relationships, and diversify revenue opportunities within clinical services.

PipeBio

Pre Seed Round in 2021
Pipe | bio builds bioinformatics solutions to help optimize development of antibodies and antibody-like-therapeutics.

InpharmD

Seed Round in 2021
Every hospital hires clinical pharmacists to answer drug-related questions from doctors. They outsource this to us because we’re more efficient.

Neurolytic Healthcare Ltd.

Seed Round in 2021
Neurolytic Healthcare Ltd. is a company based in Oxford, United Kingdom, specializing in the design, development, manufacturing, and delivery of digital and genomic-based diagnostic tools and medical devices aimed at treating migraine and related neurological disorders. Established in 2016, the company focuses on personalized medicine by integrating genetic and biomarker data to enhance diagnostic accuracy and assist clinicians in determining optimal treatment strategies. Its product offerings include a diagnostic support tool, a pharmacogenetic test, and a mobile application designed for predicting migraine events. Through these innovative solutions, Neurolytic Healthcare aims to improve the management and treatment of neurological conditions.

Truepill

Series C in 2020
Truepill is a B2B pharmacy fulfillment service. They provide a pharmacy API and fulfillment of medications to 50 states from their own facilities. They work directly with D2C consumer brands (e.g. Hims, Nurx), digital health companies, and other healthcare organizations. They are a team of 150 employees and have raised funding from Initialized Capital, Y Combinator, Slow Ventures, Sound Ventures, Tuesday Capital, Foundation Capital, Index Ventures, Social Capital, Box Group, Joe Montana, and others. Founded in 2016 by Umar Afridi and Sid Viswanathan, Truepill is headquartered in San Mateo, California.

Farmako

Seed Round in 2020
Farmako Healthcare Private Limited develops health record maintenance application. The company’s application helps users to maintain lab reports, prescriptions, bills, and vaccinations information of patients from all doctors digitally at one place and offers access to medical history of patients to their doctors. The company was founded in 2019 and is based in Panaji, India.

Gilgamesh Pharmaceuticals

Seed Round in 2020
Gilgamesh Pharmaceuticals, Inc. is a preclinical biotechnology company founded in 2019 and based in New York, focused on developing innovative psychotropic drugs aimed at treating mental illnesses. The company specializes in oral arylcyclohexylamine and psychedelic medicines designed to address neuropsychiatric conditions such as depression, anxiety, substance use disorders, and stress-related issues. By leveraging a combination of medicinal chemistry, neuroscience, and drug development expertise, Gilgamesh Pharmaceuticals is committed to creating novel chemical entities that can effectively aid patients suffering from central nervous system disorders, thereby enhancing their recovery process.

Ophelia

Seed Round in 2020
Ophelia Health, Inc. specializes in medication-assisted treatment for individuals struggling with opioid dependence. The company employs a digital platform to facilitate teleconferenced consultations between patients and licensed clinicians, allowing for convenient access to treatment from home. Ophelia provides not only prescription medications but also therapeutic support, aiming to eliminate the stigma often associated with traditional rehabilitation programs. Founded in 2019 and based in Philadelphia, Pennsylvania, Ophelia emphasizes a patient-centered approach that respects individual choices and prioritizes privacy. The organization combines expertise from various fields, including medicine and technology, to deliver evidence-based care and support to those seeking to overcome opioid addiction.

1910 Genetics

Seed Round in 2020
AI for new drug discovery

Felix Biotechnology

Seed Round in 2020
Felix Biotechnology is working to accelerate the deployment of novel biotherapeutics to manage infectious diseases. Felix Biotechnology's bio-therapeutics targets antibiotic-resistant bacteria to manage infectious diseases precisely and effectively, allowing healthcare professionals to manage urgent microbial challenges in human health.

EncepHeal Therapeutics

Seed Round in 2019
EncepHeal Therapeutics is a Therapeutics company. EncepHeal Therapeutics is Non-addictive prescription substitutes have been a very popular solution for people addicted to drugs like tobacco and opioids. EncepHeal Therapeutics is creating medications to help the 2.5 million cocaine and methamphetamine addicts have a similar option.

1910 Genetics

Seed Round in 2019
AI for new drug discovery

Circumvent

Pre Seed Round in 2019
Circumvent Pharmaceuticals is focused on developing novel therapeutics to address the significant unmet needs of patients with neurodegenerative diseases. Founded in 2017 and based in Portland, Oregon, the company is dedicated to drug discovery and development for both rare and common heritable forms of neurodegeneration. Circumvent is particularly working on drug programs targeting Batten disease and other related disorders, aiming to provide precision medicines that can help patients overcome these challenging conditions. The company is supported by funding from various organizations, including the National Institutes of Health and private investors.

Truepill

Series A in 2019
Truepill is a B2B pharmacy fulfillment service. They provide a pharmacy API and fulfillment of medications to 50 states from their own facilities. They work directly with D2C consumer brands (e.g. Hims, Nurx), digital health companies, and other healthcare organizations. They are a team of 150 employees and have raised funding from Initialized Capital, Y Combinator, Slow Ventures, Sound Ventures, Tuesday Capital, Foundation Capital, Index Ventures, Social Capital, Box Group, Joe Montana, and others. Founded in 2016 by Umar Afridi and Sid Viswanathan, Truepill is headquartered in San Mateo, California.
Osh's Affordable Pharmceuticals produces generic drugs at low prices. It connects patients with pharmacies that sells low-cost medicines. Alex Oshmyansky founded Osh's Affordable Pharmaceuticals in 2016. Its headquarters is in Fremont in California.

Macromoltek Inc

Seed Round in 2018
Macromoltek does computational drug discovery for pharma companies, focusing on antibodies for therapeutics and diagnostics. This mother-daughter team’s approach aims to make research for everything from flu to cancer treatments an order of magnitude faster. With an accelerated process to discover antibodies, medical researchers can (1) craft targeted treatment plans for previously undruggable targets and (2) overcome patients’ drug resistance, a major challenge when treating diseases caused by bacteria, viruses, and parasites.

Avro

Seed Round in 2018
Avro Life Science is a Canadian company focused on developing transdermal drug delivery systems, specifically medicated skin patches designed for the pediatric and elderly populations. Utilizing a novel biopolymer as a platform, Avro's technology enables passive delivery of small molecules and drugs directly into the bloodstream, allowing for a slow-release mechanism. This innovative approach aims to enhance medication accessibility while minimizing the impact on the liver, ultimately improving health outcomes and quality of life for its patients.

NimbleRx

Series B in 2017
Provider of on demand drug delivery platform intended to create a better experience for patients at a lower price. Nimble partners with pharmacies nationwide to provide prescription delivery, as well as a mobile app for patients to manage and review prescriptions/orders from their phone.

Truepill

Seed Round in 2017
Truepill is a B2B pharmacy fulfillment service. They provide a pharmacy API and fulfillment of medications to 50 states from their own facilities. They work directly with D2C consumer brands (e.g. Hims, Nurx), digital health companies, and other healthcare organizations. They are a team of 150 employees and have raised funding from Initialized Capital, Y Combinator, Slow Ventures, Sound Ventures, Tuesday Capital, Foundation Capital, Index Ventures, Social Capital, Box Group, Joe Montana, and others. Founded in 2016 by Umar Afridi and Sid Viswanathan, Truepill is headquartered in San Mateo, California.

Nephrogen

Seed Round in 2017
Nephrogen is a biotechnology company dedicated to developing novel diagnostics and research tools for various life threatening diseases.

Multiply Labs

Seed Round in 2016
Multiply Labs manufactures personalized pharmaceutical capsules that are tailor-made to the unique needs of each patient. Multiply Labs’ product is enabled by the combination of pharmaceutical science with robotics technology. The company has built and operates a unique robotic pharmaceutical manufacturing facility. Multiply Labs is the first company ever to bring to the market 3D printed capsules.

NimbleRx

Seed Round in 2015
Provider of on demand drug delivery platform intended to create a better experience for patients at a lower price. Nimble partners with pharmacies nationwide to provide prescription delivery, as well as a mobile app for patients to manage and review prescriptions/orders from their phone.

20n

Seed Round in 2014
At 20n, They use algorithms to engineer microbes. Specifically, their algorithms engineer microbes to make chemicals. Like yeast produces alcohol during beer brewing, their engineered microbes will produce chemicals with therapeutic health and industrial biotech applications. The best illustration of this DARPA-backed technology is the bacteria They engineered to produce Paracetamol (also known as acetaminophen, and sold under the brand name Tylenol). Aside from this bacteria, there is no known natural way of producing acetaminophen. They are building data mining technology that will allow us to enable the bioproduction of a whole spectrum of valuable molecules. Below is the map of every chemical that can be made biologically, as discovered by 20n's algorithms.

Medmonk

Seed Round in 2012
Medmonk is based on the premise that it's in everyone's best interest for medications to be used regardless of price. Patients get the care and medications they need, insurers are protected against larger claims, and pharmaceutical companies and pharmacies get maximum use of their medications. Co-founder Somaira Punjwani, an HIV specialty pharmacist, had to invent a process as an alternative to turning away patients who struggled with their co-pay. She did this manually for over three years with overwhelming positive feedback from grateful patients who could now afford their medications.

Alphacare

Seed Round in 2009
Alphacare is a universal mental healthcare system for psychedelic medicine. Its primary operation is the integration of approved and proposed FDA psychedelic medicines into a new model, enabling mental health patients to get proper treatment.