Y Combinator is a startup accelerator based in Mountain View, California, founded in 2005. It has pioneered a new funding model for early-stage startups by investing a modest amount of capital, typically around $150,000, in a large number of companies twice a year. Over a three-month program, Y Combinator collaborates closely with these startups to prepare them for investor pitches and enhance their business strategies. Each funding cycle concludes with Demo Day, where startups present to an exclusive audience of investors. Y Combinator focuses on various sectors, including business software, education, healthcare, and financial technology, among others. In addition to initial funding, it offers ongoing support through its extensive alumni network. Since its inception, Y Combinator has funded over 630 startups, contributing significantly to the entrepreneurial ecosystem in Silicon Valley and beyond.

Techstars Central LLC, founded in 2006 and based in Boulder, Colorado, operates as a startup accelerator and venture capital firm focused on supporting early-stage technology-oriented companies. It specializes in a mentorship-driven accelerator program, selecting ten startups each summer to participate in a three-month incubation period, offering funding of $120,000 in exchange for equity. Techstars invests primarily in sectors such as fintech, artificial intelligence, blockchain, augmented reality, and IoT, while avoiding investments in medical devices, healthcare technology, and local service-oriented businesses. In addition to its primary accelerator, Techstars has various specialized programs, including those focused on music, retail, mobility, and social impact, with global reach extending to regions such as Africa, Asia, and Latin America. The firm prefers taking minority stakes, typically between six and ten percent, without seeking board representation or investor rights. Techstars has built a robust network of entrepreneurs, mentors, and corporate partners to foster innovation and growth within its portfolio, which includes over 1,000 companies with a significant collective market capitalization.

SOSV is a global venture capital firm founded in 1995 and headquartered in Princeton, New Jersey. Specializing in seed-to-growth stage investments, SOSV operates multiple accelerator programs worldwide, including HAX for hardware, IndieBio and RebelBio for life sciences, Chinaccelerator and MOX for cross-border internet ventures, Food-X for innovative food solutions, and dlab for blockchain technology. The firm focuses on investments in revolutionary deep technologies aimed at improving human and planetary health, as well as cross-border markets, particularly in Asia. SOSV invests in approximately 150 startups annually, providing support through its resources to accelerate product development and scaling. Over its two-decade history, SOSV has established a strong reputation, consistently ranking among the top venture capital firms globally.

Plug and Play, founded in 2006 and based in Sunnyvale, California, operates as a business accelerator and venture capital firm that focuses on early-stage and seed investments in technology startups. The firm runs 12 industry-specific accelerator programs annually, connecting startups with corporate partners and investors to foster collaboration and growth. Plug and Play's investment strategy encompasses a wide range of sectors, including fintech, health and wellness, travel, cybersecurity, and sustainability, allowing it to support diverse startups from any country. The firm provides various resources, including funding, mentorship, office space, and networking opportunities, and has a global presence with offices in North America, Europe, and Asia. Plug and Play has a strong track record, having helped numerous startups secure over $9 billion in funding since its inception. Its programs aim to refine business models and facilitate introductions to potential investors, ultimately contributing to the growth of the startup ecosystem.

Sequoia Capital is a prominent venture capital firm founded in 1972 and based in Menlo Park, California. The firm specializes in investing across various stages of startups, including seed, early, and growth stages, and focuses on sectors such as technology, healthcare, financial services, internet, and mobile. Sequoia typically invests between $100,000 and $1 million in seed companies, $1 million to $10 million in early-stage ventures, and $10 million to $100 million in growth investments. The firm operates globally, with significant activities in regions like Israel, China, and India, where it partners with dynamic founders to build successful companies. Sequoia's extensive portfolio includes notable firms and offers valuable insights and resources, benefiting from decades of experience in the venture capital landscape.

StartUp Health is dedicated to improving global health and well-being through its long-term mission to collaborate with entrepreneurs, known as Health Transformers, in pursuing ambitious health goals termed "health moonshots." Since its inception in 2011, StartUp Health has cultivated a diverse portfolio, currently comprising over 330 companies spanning six continents and 26 countries. These companies focus on various critical health areas, including access to care, reducing costs, curing diseases, addressing women's and children's health, promoting nutrition and fitness, enhancing brain health, mental well-being, addiction recovery, longevity, and pandemic response. The organization is supported by a network of prominent investors and health organizations, positioning it as a leader in health innovation.

General Catalyst Group Management, LLC is a private equity and venture capital firm founded in 2000 and based in Cambridge, Massachusetts, with additional offices in North America and Europe. The firm specializes in early-stage and growth equity investments, focusing on a diverse range of sectors including technology, advanced materials, clean energy, cybersecurity, healthcare, and consumer services. General Catalyst seeks to invest in companies that demonstrate strong growth potential, typically targeting those with an EBITDA between $3 million and $30 million and minimum revenues of $10 million. The firm has managed eight venture capital funds with approximately $3.75 billion in capital commitments. It emphasizes building lasting relationships with entrepreneurs and provides mentorship to foster success, enabling companies to scale effectively. General Catalyst primarily invests in North America and Australia, with a preference for seed investments in Silicon Valley, New York, and Boston.

500 Global, formerly known as 500 Startups, is a venture capital firm and incubator based in Mountain View, California, founded in 2010. The firm specializes in seed investments, primarily focusing on early-stage technology and financial services startups across various sectors, including biotech, e-commerce, fintech, and digital healthcare. 500 Global operates a four-month accelerator program, where it typically invests between $0.05 million and $1 million for a 5 to 10 percent equity stake in companies with at least $100,000 in monthly revenue. The firm targets a global market, with particular emphasis on regions such as the Middle East, Asia, Europe, and Latin America. Since its inception, it has invested in over 2,200 startups and supports the growth of innovation ecosystems through educational programs and partnerships. 500 Global also prioritizes investments in companies led by minority founders, reflecting its commitment to diverse entrepreneurial leadership.

Khosla Ventures is a venture capital firm established in 2004 by Vinod Khosla, a co-founder of Sun Microsystems. Based in Menlo Park, California, the firm manages over $5 billion and primarily invests in early-stage technology companies throughout the United States. Khosla Ventures provides capital, strategic advice, and venture assistance to entrepreneurs focused on breakthrough innovations across various sectors, including consumer technology, enterprise solutions, health, education, agriculture, and sustainable energy. The firm has a particular interest in high-risk, high-reward opportunities, often acting as a sole investor in "science or innovation experiments." Investment sizes typically range from $100,000 to over $20 million, allowing Khosla Ventures to support both traditional ventures and unconventional projects.

Alumni Ventures Group, LLC is a venture capital firm founded in 2013 and based in Manchester, New Hampshire, with additional offices in North America. The firm specializes in seed, early-stage, and late-stage pre-IPO investments, focusing on companies that have an alumni connection and an institutional lead investor with relevant expertise. It offers high-quality, diversified venture portfolios to individual investors, particularly accredited alumni from top entrepreneurial schools, who previously lacked access to venture capital opportunities. Alumni Ventures Group invests between $0.01 million and $3 million in various sectors and geographies, without seeking board or observer seats. Additionally, the firm provides focused funds that enable any accredited investor to access a diverse venture portfolio, allowing for investment across different types, sectors, stages, and geographical locations.