Xencor

Xencor, Inc. is a clinical-stage biopharmaceutical company headquartered in Monrovia, California, specializing in the discovery and development of engineered monoclonal antibodies and other protein therapeutics aimed at treating severe and life-threatening diseases. The company leverages its proprietary XmAb technology platform to create a range of antibody product candidates for various conditions, including cancer and autoimmune diseases. Notable candidates in its portfolio include XmAb5871 and AIMab7195, both targeting autoimmune disorders, and several bispecific antibodies currently in clinical trials, such as XmAb14045 for acute myeloid leukemia and plamotamab for B-cell malignancies. Additionally, Xencor is advancing therapies for neuroendocrine tumors and gastrointestinal stromal tumors, as well as developing preclinical bispecific antibodies for various cancers. The company generates revenue through research and development collaborations and licensing agreements with major pharmaceutical firms. Founded in 1997, Xencor is committed to addressing unmet medical needs through innovative therapeutic solutions.

Bart Cornelissen

CFO

1 past transactions

Zenas BioPharma

Series B in 2022
Zenas BioPharma is a clinical-stage biopharmaceutical company based in Florida, dedicated to developing immune-based therapies for patients. The company's lead product candidate, obexelimab, is a bifunctional monoclonal antibody that targets both CD19 and FcγRIIb, which are found on B cells. This innovative approach aims to inhibit the activity of B cells involved in various autoimmune diseases while preserving their overall population, thus offering a potential therapeutic advantage over traditional treatments that deplete these cells.
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