25Madison

25Madison is a New York based early-stage venture platform and investment firm founded in 2018. It operates a general studio that builds companies across verticals, a healthtech initiative called 25m health developed in partnership with LifePoint Health, a ventures fund that backs pre-seed to series A startups in B2B software, fintech, and healthtech, and 25m create, a brand and experience agency providing brand strategy, visual identity, experience design, and digital marketing. The group maintains offices in New York, with additional offices in Miami, Atlanta, and Tel Aviv.

Matthew Fremont-Smith

Co-Founder, President and Board Member

Sara Garson

Investor

Kirk Posmantur

Co-Founder and Board Member, Chief Partnership Officer

Grant Silow

Managing Director

Alex Toporek

Associate, Incubations and Investments

57 past transactions

Ranger AI

Pre Seed Round in 2025
Ranger AI helps manufacturers decrease response time to win new business, increase bid throughput.

Keragon

Seed Round in 2025
Keragon operates a healthcare integration and automation platform designed to simplify and automate workflows. It connects disparate systems within healthcare organizations, automating tasks such as appointment scheduling, patient intake, billing, and more. This enables healthcare product teams to enhance efficiency, reduce costs, and improve patient care.

Paxton

Series A in 2025
Paxton is a legal tech company that utilizes cutting-edge AI technology to transform the way legal professionals work. Our robust AI platform ingests vast sources of legal information, including all state and federal laws and regulations, and provides precise, relevant, and insightful responses to user queries. From answering questions about regulations to drafting legal documents, Paxton AI transforms the legal research and analysis process, saving time and increasing efficiency.

Wilya

Seed Round in 2024
Wilya is a developer of workforce management software focused on transforming the future of work in industrial manufacturing and logistics. Leveraging extensive expertise in manufacturing and human resources, the company has identified the need for innovative technologies that support manufacturers in managing a flexible workforce. Wilya's software platform aims to enhance the work culture within factories by promoting diversity, minimizing mandatory overtime, and operationalizing flexibility. This approach challenges traditional rigid work schedules, enabling manufacturers to tap into diverse talent pools and effectively create and manage a more dynamic and engaged workforce. Through its solutions, Wilya seeks to address the evolving needs of the manufacturing sector while maximizing operational efficiency.

Quantivly

Seed Round in 2023
Quantivly, Inc., established in 2019 and headquartered in Somerville, Massachusetts, specializes in developing artificial intelligence-based solutions tailored for the field of radiology. The company focuses on enhancing data liquidity and providing analytical tools that enable radiology providers to make informed decisions, thereby increasing access to medical imaging services. Quantivly's platform is designed to manage and analyze MRI imaging workflows by cleaning and harmonizing scanner data, resulting in a vendor-neutral and comprehensive source of operational knowledge. This innovative approach supports radiology departments and imaging centers in utilizing data analytics to improve decision-making, facilitate new research initiatives, and enhance the overall patient experience in healthcare.

Midi Health

Series A in 2023
Midi Health is a virtual care clinic specializing in women's health. It offers personalized treatment protocols for depression, gynecological cancer, and menstrual issues, delivered by clinicians trained in female midlife health. The platform leverages at-home labs, prescription medications, supplements, and lifestyle coaching to provide comprehensive care.

Paxton

Seed Round in 2023
Paxton is a legal tech company that utilizes cutting-edge AI technology to transform the way legal professionals work. Our robust AI platform ingests vast sources of legal information, including all state and federal laws and regulations, and provides precise, relevant, and insightful responses to user queries. From answering questions about regulations to drafting legal documents, Paxton AI transforms the legal research and analysis process, saving time and increasing efficiency.

Croissant

Seed Round in 2023
Croissant provides Guaranteed Buybacks at Point of Sale and beyond, enabling retailers and consumers to benefit from the resale ecosystem.

Thrive Health Tech

Pre Seed Round in 2023
Thrive Health Tech is a healthcare-focused mobile company that develops a communication platform to close the digital divide and improve healthcare outcomes through sustained member engagement. The platform supports digital health strategies with a vertically integrated wireless service network, mobile devices, and a custom phone operating system, enabling healthcare organizations to reach and engage members efficiently and to drive better patient outcomes.

Novacy

Pre Seed Round in 2023
Novacy specializes in conversational intelligence, assisting businesses in closing more sales by analyzing audio, text, and body language data. Its platform automates the review of customer interactions, identifying each representative's strengths and areas for improvement at scale.

Pattern

Seed Round in 2023
Pattern is a financial services company that offers a modern membership combining access to a personal financial advisory team with a robo-advisory platform. It also develops financial software that helps users plan finances, manage assets, and access private equity and other financial services. The platform aims to maximize asset value while balancing risk, enabling clients to grow their wealth and achieve long-term financial goals.

Swap Health

Seed Round in 2022
Swap Health operates a telehealth platform that connects individuals with registered dietitians and health coaches for personalized nutrition guidance, tailored to chronic conditions and prevention. The service aims to improve access for households with low or moderate incomes to evidence-based nutrition support and affordable healthy food options, including cash back on groceries.

VineSight

Seed Round in 2022
Vinesight is a developer of a media analysis platform focused on identifying and combating misinformation and fake news on social media. Utilizing advanced artificial intelligence technology, the platform is designed to operate in a content-agnostic manner, allowing it to analyze a wide range of information across different networks. Vinesight provides clients with deep behavioral science insights, enabling them to swiftly detect viral misinformation and manage potential threats to their brand's reputation. Through its innovative approach, Vinesight aims to create accountability in the sharing of digital information.

Demoleap

Seed Round in 2022
Demoleap is an AI-powered platform designed to assist sales teams in conducting more effective product demonstrations. Founded in Israel with additional offices in Delaware and Ireland, the company's technology focuses on enhancing live demos by automating tracking and logging of demo activities. This allows sales representatives to concentrate on delivering value rather than managing the technical aspects of the demonstration. Demoleap is backed by several prominent investors, including 25madison, Ground Up Ventures, former Cisco CMO Blair Christie, Atrium Co-Founder Peter Kazanjy, Aforza CEO Dominic Dinard, Fourand CEO Chaim Lever, and David Magerman, managing partner and CTO at Differential Ventures.

Onda

Series B in 2022
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

ModernLTV

Pre Seed Round in 2022
10%+ of annual subscription revenue is lost to unnecessary customer churn. Increased cost of living, zero switching costs, and a lack of predictive insights make it harder than ever to combat churn. Introducing ModernLTV, a no-code retention platform for consumer billers (mobile, cable/tv, insurance) and subscription businesses (streaming, health & wellness, eLearning). Powered by proprietary Retention Intelligence and purpose-built for marketers, Modern delivers real-time predictive insights and automated workflows to combat churn and maximize LTV — all with zero engineering. Launch a FREE test drive in just minutes and get a complimentary Retention Health Check. Start reducing churn today www.modernltv.com/get-started

Handspring Health

Seed Round in 2022
Handspring Health redesigns family mental healthcare delivery. It integrates in-person, digital, and device-based care through technology, health plan partnerships, and trained clinicians to make quality mental healthcare more accessible.

Eon Health

Series A in 2022
Eon Health is a healthcare technology company based in Denver, Colorado, that specializes in providing software solutions for complex patient management. Established in 2015 as Matrix Analytics and rebranded in 2018, Eon Health focuses on revolutionizing the collection, curation, and sharing of healthcare data among professionals. Its flagship software platform, EonDirect, integrates with existing electronic health record (EHR) systems to deliver actionable insights through an online dashboard, enabling healthcare providers to effectively diagnose and treat complex diseases. The company currently collaborates with 31 hospitals and manages the care of over 12,000 patients, ensuring that critical data reaches the appropriate stakeholders in a timely manner.

Sagewell Financial

Seed Round in 2022
Sagewell Financial is a company comprised of professionals from technology, insurance, financial services, and operations sectors. It is dedicated to transforming the financial landscape for older adults in the United States. The company offers a platform designed to provide security and support during retirement. This includes features such as building a personalized retirement paycheck, free checking accounts, and access to a personal retirement success advocate for guidance.

Intellihealth

Seed Round in 2021
Intellihealth develops medical technology software to diagnose obesity-related diseases. The company's flagship product, Evolve, enables medical providers to offer effective medical obesity treatment to new and existing patients, both via telehealth and in person.

Intellihealth

Seed Round in 2021
Intellihealth develops medical technology software to diagnose obesity-related diseases. The company's flagship product, Evolve, enables medical providers to offer effective medical obesity treatment to new and existing patients, both via telehealth and in person.

Opsera

Series A in 2021
Opsera empowers software and DevOps engineers by offering a cloud-based continuous orchestration platform. This platform enables the use of preferred CI/CD tools, reduces manual scripting, and provides unified insights across the entire DevOps lifecycle. It aims to increase software velocity, improve operational efficiency, and offer unparalleled visibility for business leaders.

Boosted Commerce

Series A in 2021
Boosted Commerce is an e-commerce growth company that acquires, invests in, and grows consumer brands sold on Shopify and Amazon (FBA). It supports third-party sellers by acquiring brands, deploying capital, and driving product development across multiple verticals, enabling merchants to move on while delivering fair market-driven terms. Through strategic brand expansion, distribution optimization, and operational support, Boosted Commerce seeks to accelerate revenue growth and expand the reach of its portfolio on digital marketplaces.

Coterie

Seed Round in 2021
Coterie offers a curated selection of elevated party supplies. Customers can find everything they need to throw a memorable party with Coterie's curated collections. Coterie's sells everything from party sets to glitter candles. Customers can find exactly what they want by filtering by occasion, color, or product type.

OROS

Series A in 2021
OROS is a material technology company specializing in innovative thermal solutions for outerwear. The company has developed and integrated patented Aerogel-based Solarcore technology, which allows for efficient delayering of apparel. This technology, originally derived from NASA's insulation used in space suits and Mars Rovers, has been adapted by OROS to create outerwear that is thinner, warmer, and more flexible. By infusing Aerogel into their products, OROS aims to redefine the possibilities of outdoor clothing, enhancing performance while maintaining comfort.

Onda

Series A in 2021
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

Sourse

Seed Round in 2021
Sourse is a food technology company dedicated to setting high standards for efficacy and sustainability in the functional snacks category. It specializes in developing new formats for vitamins and supplements, with a mission to design clean, delicious, and functional snacks that serve both people and the planet. The company's first product is vitamin-infused chocolate.

US Bitcoin

Series A in 2021
US Bitcoin Corporation operates data centers that secure the Bitcoin network through mining activities. It offers cost-effective mining services to clients, enabling them to participate in Bitcoin validation processes. The company prioritizes sustainability by utilizing low- and no-carbon energy sources for its operations.

Truehold

Seed Round in 2021
Truehold offers a sale-leaseback service designed to provide senior citizens with an alternative housing option. The company purchases clients' homes for full value, allowing them to continue living there while relieving them of maintenance and financial responsibilities.

Onda

Series A in 2021
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

Great American Plant

Seed Round in 2021
Great American Plant offers plant-based protein solutions for user brands, menus, and restaurants. They provide plant-based meatballs, burger patties, and sausage patties. Their solutions reduce greenhouse gas emissions.

Ruby

Pre Seed Round in 2020
Ruby specializes in the health and wellness of seniors and their families with home maintenance and healthcare services for a living. Founded in 2020, Ruby's mission empowers seniors to maintain their independence by living in and loving their homes.

Park & Diamond

Venture Round in 2020
Park & Diamond, Inc. is a company that specializes in the design and manufacture of ultra-portable and collapsible cycling helmets. Founded in 2015, the company is headquartered in Brooklyn, New York. Park & Diamond's innovative helmet offers an alternative to traditional bulky designs, featuring a compact construction that is both lightweight and efficient in absorbing and dissipating impact energy. The helmet includes interchangeable skins, hand-washable layers, and ultraviolet protection, making it a practical choice for cyclists and kick scooter users.

Onda

Seed Round in 2020
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

harbor

Pre Seed Round in 2020
Harbor is a Los Angeles-based company founded in 2019 that specializes in retailing public safety equipment and providing disaster preparedness and planning services. The company has developed an app and readiness platform designed to help users assess and enhance their preparedness for emergencies. By curating expert advice and personalizing key aspects of home safety, Harbor seeks to simplify the process of getting ready for unexpected situations. The platform also incorporates elements of automation and gamification to make preparedness an engaging and integral part of daily life, ultimately promoting peace of mind for its users.

harbor

Seed Round in 2020
Harbor is a Los Angeles-based company founded in 2019 that specializes in retailing public safety equipment and providing disaster preparedness and planning services. The company has developed an app and readiness platform designed to help users assess and enhance their preparedness for emergencies. By curating expert advice and personalizing key aspects of home safety, Harbor seeks to simplify the process of getting ready for unexpected situations. The platform also incorporates elements of automation and gamification to make preparedness an engaging and integral part of daily life, ultimately promoting peace of mind for its users.

Noops

Pre Seed Round in 2020
Noops, Inc. is a manufacturer and retailer specializing in plant-based oat milk pudding products. Founded in 2019 and based in Roslyn, New York, the company offers a diverse range of flavors including mocha, cocoa, French toast, and sticky bun. Noops focuses on providing healthier snack alternatives made from clean ingredients such as organic oats, dates, and sunflower seed proteins. Its products are vegan, non-GMO, OU Kosher, and allergen-friendly, with no added sugar, making them appealing to health-conscious consumers. The company sells its offerings through an online platform, promoting immunity-boosting prebiotics and heart-healthy whole grains. Originally known as SuperBox Brands, Inc., the company rebranded to Noops, Inc. in October 2019.

Onda

Seed Round in 2020
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

Demoleap

Pre Seed Round in 2020
Demoleap is an AI-powered platform designed to assist sales teams in conducting more effective product demonstrations. Founded in Israel with additional offices in Delaware and Ireland, the company's technology focuses on enhancing live demos by automating tracking and logging of demo activities. This allows sales representatives to concentrate on delivering value rather than managing the technical aspects of the demonstration. Demoleap is backed by several prominent investors, including 25madison, Ground Up Ventures, former Cisco CMO Blair Christie, Atrium Co-Founder Peter Kazanjy, Aforza CEO Dominic Dinard, Fourand CEO Chaim Lever, and David Magerman, managing partner and CTO at Differential Ventures.

REWIRE

Pre Seed Round in 2020
REWIRE is a cutting-edge health and fitness training system specifically designed to upgrade whole-body performance. REWIRE's proprietary system combines five technologies into a full-stack exercise and recovery program that optimizes sleep, energy, focus, and cognitive and athletic performance.

Tigapo

Seed Round in 2020
Tigapo operates a digital platform that connects coin-operated machines to the cloud for data collection and analysis and provides a payment platform that enables services to be paid with smartphones and NFC tags. The platform supports remote control and management of machines, links devices to cloud services, and collects real-time data while profiling customers and using algorithms to autonomously manage machines remotely. This enables owners to reduce operational costs, increase revenues, improve customer engagement, streamline operations, and enhance the overall entertainment experience.

Onda

Pre Seed Round in 2020
Onda is a spirits brand that offers canned sparkling tequila beverages made with blanco tequila and real fruit juice. The drinks are crafted with sparkling water and all-natural ingredients to deliver a light, refreshing taste with a hint of tequila and zero carbs. Each can contains 5% ABV, 100 calories, zero sugar, and is gluten-free. The brand draws on 1990s surf culture for its aesthetic, positioning itself as a convenient, lower-calorie tequila option for consumers seeking a real-fruit, gluten-free beverage experience.

Forks Over Knives

Seed Round in 2019
Forks Over Knives is a multimedia brand promoting plant-based lifestyles. It offers ready-to-eat plant-based meals, online cookery courses, a meal planner, and resources for healthier living.

Park & Diamond

Seed Round in 2019
Park & Diamond, Inc. is a company that specializes in the design and manufacture of ultra-portable and collapsible cycling helmets. Founded in 2015, the company is headquartered in Brooklyn, New York. Park & Diamond's innovative helmet offers an alternative to traditional bulky designs, featuring a compact construction that is both lightweight and efficient in absorbing and dissipating impact energy. The helmet includes interchangeable skins, hand-washable layers, and ultraviolet protection, making it a practical choice for cyclists and kick scooter users.

Verifi Water

Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.

Parmela Creamery

Seed Round in 2019
Parmela Creamery is a New York City-based manufacturer specializing in plant-based cheese alternatives. It produces a range of products, including cashew and nut cheeses, sold through various food retail stores.

Steady

Series A in 2019
Steady removes barriers to earn through its income intelligence that supports over 3 million hourly, 1099 and mixed-earners in earning more, an average of over $5,500 per year. Steady's view of income also applies its technology for purposes of income measurement that fills the wage data gap for public and private sector entities that service this worker population in areas such as the administration of public sector benefits. Steady was founded in 2017.

The Great American Turkey

Seed Round in 2019
The Great American Turkey Co., LLC is a producer and distributor of turkey products based in Monsey, New York, established in 2017. The company specializes in offering a range of turkey items, including cutlets, strips, sausages, bratwursts, and hotdogs, catering to both retail stores and online consumers. Committed to health-conscious practices, The Great American Turkey Co. emphasizes better-for-you, sustainably sourced protein options, ensuring that its products are free from antibiotics, preservatives, and added hormones. By providing a diverse selection of turkey meat products, the company aims to meet the needs of consumers looking for nutritious alternatives for various meals.

Verifi Water

Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.

Skylark

Seed Round in 2019
Skylark Travel Group, Inc., founded in 2014 and based in New York, operates as an online luxury travel agency that offers a range of travel products and solutions. The company specializes in air tickets, customized holiday packages, and hotel bookings, combining technology with personalized service. Skylark's platform features a team of full-service travel advisors and privately negotiated airfare, enhancing the booking experience while providing clients with exceptional vacations. Through partnerships with luxury hotels and resorts, Skylark aims to deliver seamless amenities and unique experiences, ensuring clients receive both competitive pricing and expert advice.

Verifi Water

Seed Round in 2019
Verifi Water is a water-monitoring platform that delivers real-time water quality intelligence. Their water quality surveillance systems are based on proprietary, advanced material technologies that enable the rapid detection of pathogens, contaminants, and chemicals of concern.

Mud\Wtr

Pre Seed Round in 2018
Mud\Wtr is a producer of organic beverages focused on providing health-conscious alternatives to traditional coffee. The company offers a unique blend of ingredients, including adaptogenic mushrooms like reishi, lion's mane, and cordyceps, combined with cacao, chia, turmeric, cinnamon, and sea salt. These formulations aim to deliver energy, enhance focus, and support immune health without the jitters or crashes often associated with caffeine. Mud\Wtr is committed to promoting healthy minds through the establishment of beneficial habits, positioning itself as a suitable choice for consumers seeking natural beverage options that support overall well-being.

BOU Brands

Series B in 2018
BOU Brands, LLC is a New York-based company that specializes in producing bouillon cubes and ready-to-eat soups. Incorporated in 2016, BOU Brands offers a diverse range of products, including soups, risotto, dips, pies, pizza, and salad. The company is dedicated to creating flavorful, healthier, and high-quality food options that prioritize convenience. BOU Brands emphasizes the use of real and all-natural ingredients in their offerings, ensuring that consumers do not have to compromise on taste or quality.

Steady

Series A in 2018
Steady removes barriers to earn through its income intelligence that supports over 3 million hourly, 1099 and mixed-earners in earning more, an average of over $5,500 per year. Steady's view of income also applies its technology for purposes of income measurement that fills the wage data gap for public and private sector entities that service this worker population in areas such as the administration of public sector benefits. Steady was founded in 2017.

Tigapo

Seed Round in 2018
Tigapo operates a digital platform that connects coin-operated machines to the cloud for data collection and analysis and provides a payment platform that enables services to be paid with smartphones and NFC tags. The platform supports remote control and management of machines, links devices to cloud services, and collects real-time data while profiling customers and using algorithms to autonomously manage machines remotely. This enables owners to reduce operational costs, increase revenues, improve customer engagement, streamline operations, and enhance the overall entertainment experience.
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