Ontario Brain Institute

Grey Matter Neurosciences is a neurotechnology company specializing in the development of innovative medical devices and drug-device combinations to address age-related brain disorders, with a primary focus on dementia. Their flagship technology is a portable ultrasound helmet, designed to non-invasively enhance brain function in seniors with Alzheimer's disease.

Yellowbird Diagnostics develops innovative imaging agents aimed at enhancing diagnostic imaging across various medical procedures. The company specializes in creating plug-and-play dyes that improve the detection of disorders affecting the brain, heart, and kidneys. By providing molecular information on conditions such as inflammation and cancer, Yellowbird's technologies reveal previously undetectable signs of disease. This advancement allows healthcare professionals to make more informed and effective medical decisions, ultimately facilitating earlier diagnosis and treatment for patients.

RetiSpec is a company focused on advancing early detection of Alzheimer’s Disease through its innovative non-invasive eye scanning technology. By employing AI-driven retinal imaging, RetiSpec's solution enables healthcare providers to identify neurodegenerative disease markers during a simple eye exam. This approach facilitates early diagnosis, allowing clinicians to intervene with emerging therapeutics before symptoms arise, thereby potentially impacting the progression of the disease. RetiSpec aims to make early detection accessible and affordable, contributing significantly to the management of Alzheimer's Disease.

Progress Place is a non-profit organization that provides treatment for mental illness, depression, and anxiety.

The Royal is a mental health care and academic health sciences center dedicated to providing comprehensive mental health services. The organization focuses on advocacy, research, and education, aiming to enhance the understanding and treatment of mental health disorders. Among its offerings is a geriatric outreach behavioral support program that specializes in the assessment, diagnosis, and treatment of complex mental health conditions in adults. Through its commitment to mental health care, The Royal seeks to improve the overall well-being of individuals while contributing to advancements in the field of mental health research and education.

Sonaro is a pioneering company specializing in AI-driven solutions for medical imaging. It focuses on enhancing the accuracy and efficiency of atherosclerotic plaque diagnosis and stroke risk assessment, particularly using ultrasound scans. The company's core technology transforms 2D ultrasound data into precise 3D models of carotid arteries, improving diagnostic precision, reducing operator workload, and providing rapid results. This innovation aims to make advanced vascular disease diagnosis more accessible and beneficial to patients and healthcare providers alike.

Savyn Tech operates a virtual neuroscience therapy platform focused on mental health management. The platform is designed to assist individuals dealing with post-traumatic stress disorder, anxiety, and depression by providing tools for self-management. Users can access features such as breathing exercises to alleviate panic attacks and guided eye motion therapy aimed at addressing the effects of negative memories. This approach enables individuals to take control of their mental health journey, allowing them to work through their symptoms and triggers at their own pace.

PragmaClin is a digital health innovator focused on transforming the management of Parkinson's Disease and other neurological disorders. The company develops advanced assessment tools that leverage cutting-edge technology to facilitate remote monitoring and management of movement disorders. By allowing patients to assess and track the severity of their symptoms from the comfort of their own homes, PragmaClin empowers individuals to take an active role in their health journey. This approach not only enhances the quality of care but also aims to improve the overall well-being of patients dealing with the challenges of Parkinson's Disease.

Foqus is an artificial intelligence and quantitative imaging technology company focused on enhancing magnetic resonance imaging (MRI) capabilities. The company develops advanced software that improves the speed and quality of MRI scans by leveraging quantum information algorithms and machine learning techniques. This innovative approach allows for the generation of higher-resolution medical images while enhancing the sensitivity of magnetic resonance technology. By offering these advancements, Foqus aims to enable healthcare organizations and medical professionals to perform scans more efficiently and at a lower cost, ultimately improving patient outcomes.

Axem Neurotechnology is dedicated to enhancing accessibility to neurotechnology and empowering individuals with information about their brain health to improve their quality of life. The company has developed a portable neuroimaging system that tracks and predicts recovery of movement function, particularly during rehabilitation for hemiparesis. Utilizing a proprietary optical imaging system, assessment software, and data analytics, Axem's technology measures neural biomarkers to support neurological rehabilitation. This innovative approach allows therapists to make informed treatment decisions. The services are delivered through video communication, combined with personalized home exercise programs facilitated by an intuitive brain sensor, ensuring that patients can engage in their rehabilitation from the comfort of their homes.

Think Self-Management is a company that equips medical professionals with tools and resources to help patients with chronic diseases manage their conditions more effectively. The company's platform offers evidence-based self-management interventions, focusing on reducing severe fatigue and cultivating essential self-management skills. By promoting self-management, Think Self-Management aims to enhance the quality of life for individuals living with chronic conditions, enabling them to lead happier, healthier lives.

Mesosil is a healthcare technology company specializing in the development of responsive antimicrobial materials designed to prevent infection at the interface between medical devices and tissues. Their primary focus is on dental applications, aiming to improve patient outcomes by reducing recurrent caries, detachment of dental restorations, and peri-implant infections. Mesosil's innovative technology offers long-lasting antimicrobial effects without disrupting practitioners' workflows.

Roga is a manufacturer of therapeutic wearables that aim to alleviate stress and anxiety. The company's discreet device resembles a set of headphones and works by delivering gentle electrical pulses to the brain, which signal a sense of safety to the nervous system. Utilizing a modified waveform, Roga's technology alters brain oscillation patterns and is supported by guided app-based therapies. This innovative approach enables users to experience relief and improved mental well-being.

Novela Neurotech is medical technology startup with a research legacy in neuromodulation originating in the University of Waterloo in Canada. Novela has developed the Neureka™ smart technology platform to accelerate the discovery & development of new safer treatments for epilepsy, narcotic addiction, depression, Alzheimer's, Parkinson's diseases, and many other neurological disorders

Cove Neurosciences is transforming the way data is used to understand the human brain.

Roga is a manufacturer of therapeutic wearables that aim to alleviate stress and anxiety. The company's discreet device resembles a set of headphones and works by delivering gentle electrical pulses to the brain, which signal a sense of safety to the nervous system. Utilizing a modified waveform, Roga's technology alters brain oscillation patterns and is supported by guided app-based therapies. This innovative approach enables users to experience relief and improved mental well-being.

Pearl Interactives is focused on co-creating interactive media that fosters wellness, play, and learning for children of all abilities. The company specializes in developing innovative platforms that incorporate musical play and learning experiences. Its flagship product, Bootle Blast, is a video game system utilizing mixed reality technology to engage children and youth with neuromotor conditions in exercises aimed at improving their functional abilities. By offering interactive games that are accessible and touch-free, Pearl Interactives aims to reduce anxiety and promote shared musical play, thereby enhancing the developmental experience for young children.

Raft Digital Therapeutics is a company that develops a virtual support platform aimed at facilitating unsupervised, at-home rehabilitation programs. By providing patients with an affordable solution, Raft encourages sustainable adherence to physical therapy, making the process more enjoyable and effective. The company is composed of a team of industry experts, technical specialists, and business professionals dedicated to creating products with lasting appeal. Through its innovative approach, Raft Digital Therapeutics seeks to enhance the accessibility and effectiveness of rehabilitation for patients.

Eyful is a company focused on improving the vision of individuals affected by macular degeneration. It specializes in the development of augmented reality solutions that integrate advanced artificial intelligence technology to personalize and enhance the viewing experience. By analyzing ophthalmologic and optometric data, Eyful offers prescription eyeglasses equipped with smart features that allow users to regain lost sight and improve their overall vision. The company's innovative approach aims to empower those with vision loss by providing them with effective tools to navigate their daily lives.

Ora Medical specializes in developing innovative rehabilitation technology targeted at children with mobility challenges. Its flagship product, Levity, is a smart pediatric gait trainer that employs a unique partial weight-bearing mechanism. This design not only supports children as they learn to walk but also allows them to engage with their environment using their arms, promoting greater independence. The device utilizes real-time data collection, which aids parents and clinicians in monitoring each child's rehabilitation progress. Additionally, Ora Medical's approach incorporates artificial intelligence to adapt the smart walking aid to the individual needs of each patient, facilitating personalized rehabilitation and helping them achieve optimal mobility at their own pace.

NeuroQore, Inc. is a Canadian company based in Ottawa, founded in 2012, that specializes in developing innovative neuromodulation treatment systems aimed at addressing treatment-resistant depression and related neurobehavioral conditions. The company's flagship product is a monophasic repetitive transcranial magnetic stimulation system that utilizes a unique semiconductor switch to emit a novel magnetic pulse. This technology is designed to help patients overcome challenges associated with major depressive disorder and suicidality, ultimately improving their quality of life. NeuroQore collaborates with leading universities and research clinics globally, reflecting its commitment to advancing the field of neuromodulation and transforming the lives of those affected by these debilitating disorders.

Qurcan Therapeutics is focused on developing innovative solutions for cancer treatment through advanced nanotechnology. The company is designing Manganescan®, a novel theranostic agent that serves as both an MRI contrast agent and a radio-sensitizer. This agent enhances the early detection of brain tumors by providing improved imaging capabilities, being three times more sensitive than traditional Gadolinium-based contrast agents. Manganescan® also sensitizes cancer cells, which leads to better outcomes in radiation therapy. In addition to Manganescan®, Qurcan Therapeutics is developing a drug delivery platform that aims to enhance precision medicine for solid tumors. This platform addresses challenges associated with drug release and liver accumulation seen in lipid nanoparticles, allowing for the efficient delivery of drugs, antibodies, and RNA to difficult-to-reach tumors, including those in the brain. By improving the tumor microenvironment, Qurcan Therapeutics seeks to increase therapeutic efficacy and extend patient survival rates in cancer treatment.

VRapeutic is a company dedicated to creating virtual reality software aimed at providing therapeutic support for individuals with learning disabilities and developmental disorders, including autism, ADHD, and cerebral palsy. The company's platform features software modules that deliver educational scenarios designed to instill essential life skills, such as motor, cognitive, social, and academic abilities. By integrating artificial intelligence and internet-of-things technologies, VRapeutic enhances the effectiveness of therapy sessions, allowing therapists to monitor and evaluate the impact of the treatment on users.

Diamond Therapeutics is a Toronto-based psychedelic drug development company dedicated to creating innovative therapies for mental health conditions. The company aims to harness the potential of psychedelic compounds, specifically focusing on sub-perceptual, non-hallucinogenic treatments that can be safely administered at home. By prioritizing these types of therapies, Diamond seeks to address the needs of a diverse patient population and enhance the efficacy of mental health treatments. The company’s approach includes psychopharmacology and biotechnology, with an emphasis on developing psilocybin-based medicines that may offer improved outcomes compared to existing first-line treatments, ultimately contributing to a positive impact on the global mental health crisis.

Steadiwear is a company focused on developing innovative solutions for individuals suffering from hand tremors, particularly those with Parkinson's disease. Its flagship product, the Steadi-One, is the world's first battery-free glove designed to intelligently reduce tremors. This lightweight and compact glove employs a smart fluid mechanism that provides resistance against hand tremors, allowing users to regain independence and enhance their quality of life. The Steadi-One is classified as a Class I medical device and has received FDA registration. It became available for pre-order in August 2019, with the first batch of units delivered in December 2019, followed by a full-scale launch planned for March 2020.

Inteligex is focused on developing innovative stem cell-based therapeutics aimed at restoring function in patients with spinal cord injuries, a condition currently lacking effective therapies. The company specializes in novel stem cell technologies designed to treat both acute and chronic spinal cord injuries. By modifying the spinal microenvironment and providing regenerative therapeutic cells, Inteligex aims to replace essential cells lost due to injury. This approach offers the potential to enable healthcare providers to help patients regain lost functions and improve their quality of life. If successful, Inteligex could become a pioneer in delivering treatments for spinal cord injuries and other central nervous system diseases, impacting hundreds of thousands of patients globally.

CerebTalk is a company focused on developing innovative brain-computer interfaces (BCIs) to assist individuals with severe motor impairments, such as those affected by amyotrophic lateral sclerosis, spinal cord injuries, strokes, cerebral palsy, and non-verbal autism. The company offers a communication tool that enables users with limited voluntary movements to interact more effectively. In addition to its primary focus on aiding individuals with disabilities, CerebTalk also creates wireless in-ear EEG earphones that work in conjunction with an application. This technology allows users to monitor aspects of their physical and mental wellness, including stress levels, sleep quality, and physical activity, thereby enhancing overall well-being.

Epineuron Technologies, Inc. is a medical device company based in Hamilton, Canada, established in 2016. It specializes in developing innovative treatment strategies for peripheral nerve injuries through bioelectronic medicine. The company focuses on creating a suite of surgical solutions aimed at enhancing the repair and regeneration of peripheral nerves. Epineuron's flagship product is an electroceutical device that delivers targeted electrical stimulation to accelerate the natural healing processes of injured nerves. By leveraging this technology, Epineuron aims to set a new standard of care in the field of nerve injury treatment, aspiring to become a leader in bioelectronic nerve care.

NeuroQore, Inc. is a Canadian company based in Ottawa, founded in 2012, that specializes in developing innovative neuromodulation treatment systems aimed at addressing treatment-resistant depression and related neurobehavioral conditions. The company's flagship product is a monophasic repetitive transcranial magnetic stimulation system that utilizes a unique semiconductor switch to emit a novel magnetic pulse. This technology is designed to help patients overcome challenges associated with major depressive disorder and suicidality, ultimately improving their quality of life. NeuroQore collaborates with leading universities and research clinics globally, reflecting its commitment to advancing the field of neuromodulation and transforming the lives of those affected by these debilitating disorders.

Zentrela Inc. is a neurotechnology company based in Hamilton, Canada, established in 2015. It specializes in developing advanced EEG systems aimed at enhancing safety in environments where cognitive impairment due to substances like cannabis can lead to accidents. Zentrela's flagship product, the Zentrela wellness system, is a wearable device that employs artificial intelligence to analyze brain activity, helping to prevent incidents while driving or working. The company targets the legalized cannabis industry, utilizing its proprietary technology to create a comprehensive database of consumer experiences linked to various cannabis products. This innovative approach seeks to shift the focus in the cannabis sector from plant-based data to consumer experience data, ultimately transforming product development, marketing, and sales strategies within the industry.

Stabilo Medical is a manufacturer of medical equipment and wearable devices focused on enhancing rehabilitation outcomes for stroke victims. The company has developed an innovative wearable vest designed to improve the rate and quality of rehabilitation by providing repetitive exercise to core muscles. This device features sensors that detect when a patient is slouched and assists them in returning to an upright position, allowing for safe and effective exercise without the need for a therapist. Stabilo Medical also offers a range of products related to disability and death, and inquiries about their offerings can be made through an online form on their website.

Qurcan Therapeutics is focused on developing innovative solutions for cancer treatment through advanced nanotechnology. The company is designing Manganescan®, a novel theranostic agent that serves as both an MRI contrast agent and a radio-sensitizer. This agent enhances the early detection of brain tumors by providing improved imaging capabilities, being three times more sensitive than traditional Gadolinium-based contrast agents. Manganescan® also sensitizes cancer cells, which leads to better outcomes in radiation therapy. In addition to Manganescan®, Qurcan Therapeutics is developing a drug delivery platform that aims to enhance precision medicine for solid tumors. This platform addresses challenges associated with drug release and liver accumulation seen in lipid nanoparticles, allowing for the efficient delivery of drugs, antibodies, and RNA to difficult-to-reach tumors, including those in the brain. By improving the tumor microenvironment, Qurcan Therapeutics seeks to increase therapeutic efficacy and extend patient survival rates in cancer treatment.

TruReach Health is a developer of self-help applications focused on mental wellness. The company offers a platform that provides users with accessible cognitive behavioral therapy (CBT) lessons and tools. Through its application, users can engage in step-by-step exercises and track their symptoms, allowing them to monitor their mental health condition. This enables individuals to receive support for their mental wellness in a user-friendly format, bridging the gap until they can consult with a qualified psychologist.

Curv Health is a multidisciplinary virtual clinic founded in 2017, with offices located in Toronto and Halifax. The company provides a health technology platform that enables healthcare providers to create and manage their own digital practices. Curv Health focuses on enhancing mental performance coaching accessibility, allowing young athletes to receive comprehensive support for their mental health. Through its platform, patients can schedule both virtual and in-person sessions with a range of allied healthcare professionals, including physiotherapists, dietitians, psychotherapists, and counselors. By facilitating this digital care network, Curv Health aims to improve the overall well-being of individuals and increase the number of meaningful years lived globally.

Give your patient’s family the support they deserve, so that you can focus on providing the best comprehensive care to your patient.Supports Health will improve loved ones outcomes, reduce re-admittance rates and helps families feel cared for.

Cerebian is a developer of a brain-computer interface-based operating system that revolutionizes human interaction with technology. This innovative system allows individuals, particularly those with disabilities, to control electronic devices using their brainwaves. By enabling incapacitated patients to communicate and rehabilitate, Cerebian's technology offers a significant advancement in the quality of life for individuals recovering from strokes and other neurological conditions. The company's focus is on expanding the possibilities of interaction between humans and computers, facilitating a new era of accessibility and empowerment for users.

Welbi is a company focused on enhancing the quality of life for older adults residing in senior living communities. It offers a recreational platform that simplifies administrative processes, allowing staff to dedicate more time to engaging with residents. By providing personalized programming and real-time insights, Welbi enables these communities to create unique experiences tailored to the individual needs of residents. The platform equips resident experience teams with the tools necessary to develop a comprehensive understanding of their residents, fostering deeper connections and preventing social isolation. Through these innovations, Welbi aims to transform the care and engagement practices within senior living environments.

Steadiwear is a company focused on developing innovative solutions for individuals suffering from hand tremors, particularly those with Parkinson's disease. Its flagship product, the Steadi-One, is the world's first battery-free glove designed to intelligently reduce tremors. This lightweight and compact glove employs a smart fluid mechanism that provides resistance against hand tremors, allowing users to regain independence and enhance their quality of life. The Steadi-One is classified as a Class I medical device and has received FDA registration. It became available for pre-order in August 2019, with the first batch of units delivered in December 2019, followed by a full-scale launch planned for March 2020.

HiNT is developing a wearable point-of-care monitoring device that detects a stroke with EEG and alerts high-risk patients, Its care givers, and their medical support team when the patient is having a stroke.

KalGene Pharmaceuticals Inc. is a private biotechnology company based in Candiac, Canada, focused on developing precision medicine for the treatment of Alzheimer’s disease. Established in 2006, KalGene collaborates with leading clinician-scientists and academic institutions across North America and Europe. The company specializes in creating targeted therapeutics and companion diagnostics aimed at enhancing clinical outcomes and survival rates. Through personalized medicine, KalGene seeks to predict patient responses to specific therapies before treatment begins, enabling physicians to tailor interventions based on individual biological signatures and needs.

Sound Options Tinnitus Treatments Inc. is a health technology company based in Ancaster, Canada, specializing in the development of software for tinnitus management. Founded in 2012, the company offers clinically tested, individually tailored sound therapy designed to alleviate the symptoms of tinnitus, a challenging hearing disorder that affects approximately ten percent of the population. Utilizing advanced computational neuroscience and tinnitus research, the company's software creates customized treatment plans based on each client's audiogram and tinnitus profile. The effectiveness of Sound Options' approach has been validated through studies conducted at McMaster University. The company has also formed partnerships with various independent and franchised hearing clinics across Canada to enhance accessibility for tinnitus patients and hearing healthcare professionals.