Ontario Brain Institute

Grey Matter Neurosciences is a neurotechnology company specializing in the development of innovative medical devices and drug-device combinations to address age-related brain disorders, with a primary focus on dementia. Their flagship technology is a portable ultrasound helmet, designed to non-invasively enhance brain function in seniors with Alzheimer's disease.

Yellowbird Diagnostics develops innovative imaging dyes that enhance popular medical imaging procedures. Their solutions improve early detection of disorders in the brain, heart, and kidneys by revealing previously invisible signs of disease, enabling physicians to make more informed decisions.

RetiSpec is developing a non-invasive eye scanner for the early detection of Alzheimer’s Disease pathology years before symptoms occur. This enables clinicians to intervene with emerging therapeutics at an earlier stage when there's a chance of impacting the disease.

Progress Place is a non-profit organization that provides treatment for mental illness, depression, and anxiety.

The Royal is a mental health care and academic health sciences center dedicated to providing comprehensive mental health services. The organization focuses on advocacy, research, and education, aiming to enhance the understanding and treatment of mental health disorders. Among its offerings is a geriatric outreach behavioral support program that specializes in the assessment, diagnosis, and treatment of complex mental health conditions in adults. Through its commitment to mental health care, The Royal seeks to improve the overall well-being of individuals while contributing to advancements in the field of mental health research and education.

Sonaro is a pioneering company specializing in AI-driven solutions for medical imaging. It focuses on enhancing the accuracy and efficiency of atherosclerotic plaque diagnosis and stroke risk assessment, particularly using ultrasound scans. The company's core technology transforms 2D ultrasound data into precise 3D models of carotid arteries, improving diagnostic precision, reducing operator workload, and providing rapid results. This innovation aims to make advanced vascular disease diagnosis more accessible and beneficial to patients and healthcare providers alike.

Savyn Tech operates a virtual neuroscience therapy platform focused on mental health management. The platform is designed to assist individuals dealing with post-traumatic stress disorder, anxiety, and depression by providing tools for self-management. Users can access features such as breathing exercises to alleviate panic attacks and guided eye motion therapy aimed at addressing the effects of negative memories. This approach enables individuals to take control of their mental health journey, allowing them to work through their symptoms and triggers at their own pace.

PragmaClin is a Canadian MedTech company transforming neurological care through PRIMS® (PragmaClin Intelligent Motor System), an AI-driven, depth camera-based assessment platform. Designed to address the critical gaps in neurological diagnosis and monitoring, PRIMS® automates the clinical evaluation of motor symptoms starting with Parkinson’s disease. PRIMS® enables objective, standardized, and remote assessments aligned with MDS-UPDRS scales. The platform supports clinicians, hospitals, and researchers with real-time insights, reducing the subjectivity, cost, and delay associated with current evaluations. PRIMS® is validated through global partnerships, including studies in North America, Europe, and Asia, and is advancing through a De Novo FDA regulatory pathway. Scalable to other motor conditions, PRIMS® represents the future of decentralized, equitable, and data-driven neurological care.

Foqus is an innovative company specializing in AI-driven quantitative imaging technologies. It develops software to enhance the speed and quality of Magnetic Resonance Imaging (MRI) scans, utilizing quantum information algorithms and machine learning techniques.

Axem Neurotechnology is dedicated to enhancing accessibility to neurotechnology and empowering individuals with information about their brain health to improve their quality of life. The company has developed a portable neuroimaging system that tracks and predicts recovery of movement function, particularly during rehabilitation for hemiparesis. Utilizing a proprietary optical imaging system, assessment software, and data analytics, Axem's technology measures neural biomarkers to support neurological rehabilitation. This innovative approach allows therapists to make informed treatment decisions. The services are delivered through video communication, combined with personalized home exercise programs facilitated by an intuitive brain sensor, ensuring that patients can engage in their rehabilitation from the comfort of their homes.

Think Self-Management is a company that equips medical professionals with tools and resources to help patients with chronic diseases manage their conditions more effectively. The company's platform offers evidence-based self-management interventions, focusing on reducing severe fatigue and cultivating essential self-management skills. By promoting self-management, Think Self-Management aims to enhance the quality of life for individuals living with chronic conditions, enabling them to lead happier, healthier lives.

Mesosil is a healthcare technology company specializing in the development of responsive antimicrobial materials designed to prevent infection at the interface between medical devices and tissues. Their primary focus is on dental applications, aiming to improve patient outcomes by reducing recurrent caries, detachment of dental restorations, and peri-implant infections. Mesosil's innovative technology offers long-lasting antimicrobial effects without disrupting practitioners' workflows.

Roga is a manufacturer of therapeutic wearables that aim to alleviate stress and anxiety. The company's discreet device resembles a set of headphones and works by delivering gentle electrical pulses to the brain, which signal a sense of safety to the nervous system. Utilizing a modified waveform, Roga's technology alters brain oscillation patterns and is supported by guided app-based therapies. This innovative approach enables users to experience relief and improved mental well-being.

Novela Neurotech is medical technology startup with a research legacy in neuromodulation originating in the University of Waterloo in Canada. Novela has developed the Neureka™ smart technology platform to accelerate the discovery & development of new safer treatments for epilepsy, narcotic addiction, depression, Alzheimer's, Parkinson's diseases, and many other neurological disorders

Cove Neurosciences is transforming the way data is used to understand the human brain.

Roga is a manufacturer of therapeutic wearables that aim to alleviate stress and anxiety. The company's discreet device resembles a set of headphones and works by delivering gentle electrical pulses to the brain, which signal a sense of safety to the nervous system. Utilizing a modified waveform, Roga's technology alters brain oscillation patterns and is supported by guided app-based therapies. This innovative approach enables users to experience relief and improved mental well-being.

Pearl Interactives specializes in developing interactive media for children of all abilities. Their flagship product, Bootle Blast™, is a mixed reality video game system designed to engage children and youth with neuromotor conditions in exercises that improve functional abilities.

Raft Digital Therapeutics is a company that develops a virtual support platform aimed at facilitating unsupervised, at-home rehabilitation programs. By providing patients with an affordable solution, Raft encourages sustainable adherence to physical therapy, making the process more enjoyable and effective. The company is composed of a team of industry experts, technical specialists, and business professionals dedicated to creating products with lasting appeal. Through its innovative approach, Raft Digital Therapeutics seeks to enhance the accessibility and effectiveness of rehabilitation for patients.

Eyful is a company focused on improving the vision of individuals affected by macular degeneration. It specializes in the development of augmented reality solutions that integrate advanced artificial intelligence technology to personalize and enhance the viewing experience. By analyzing ophthalmologic and optometric data, Eyful offers prescription eyeglasses equipped with smart features that allow users to regain lost sight and improve their overall vision. The company's innovative approach aims to empower those with vision loss by providing them with effective tools to navigate their daily lives.

Ora Medical develops rehabilitation technology focused on mobility impairments. The company offers smart walking aids that adapt in real time with artificial intelligence to improve patients' progress and support independent mobility. Its first device, Levity, is a pediatric gait trainer with a partial weight-bearing mechanism that lets children interact with their environment using their arms while providing real-time data for clinicians and caregivers to monitor progress.

NeuroQore, Inc. is a Canadian company based in Ottawa, founded in 2012, that specializes in developing innovative neuromodulation treatment systems aimed at addressing treatment-resistant depression and related neurobehavioral conditions. The company's flagship product is a monophasic repetitive transcranial magnetic stimulation system that utilizes a unique semiconductor switch to emit a novel magnetic pulse. This technology is designed to help patients overcome challenges associated with major depressive disorder and suicidality, ultimately improving their quality of life. NeuroQore collaborates with leading universities and research clinics globally, reflecting its commitment to advancing the field of neuromodulation and transforming the lives of those affected by these debilitating disorders.

QurCan Therapeutics develops nanotechnology-based drug delivery platforms for precision medicine in solid-tumor cancer therapy. Their platform efficiently delivers drugs, antibodies, and RNA to hard-to-reach tumors, including the brain, enhancing therapeutic outcomes.

VRapeutic develops virtual reality software for therapeutic purposes, focusing on autism, ADHD, and cerebral palsy. Its platform offers modules creating educational scenarios to instill essential life skills, supervised by therapists, tracking progress in a engaging manner.

Diamond Therapeutics is a Toronto-based company dedicated to developing novel therapies for mental health conditions. It focuses on harnessing the potential of psychedelic compounds, specifically sub-perceptual, non-hallucinogenic treatments, aiming to benefit a wide range of patients and maximize positive impact on global mental health.

Steadiwear is a company focused on developing innovative solutions for individuals suffering from hand tremors, particularly those with Parkinson's disease. Its flagship product, the Steadi-One, is the world's first battery-free glove designed to intelligently reduce tremors. This lightweight and compact glove employs a smart fluid mechanism that provides resistance against hand tremors, allowing users to regain independence and enhance their quality of life. The Steadi-One is classified as a Class I medical device and has received FDA registration. It became available for pre-order in August 2019, with the first batch of units delivered in December 2019, followed by a full-scale launch planned for March 2020.

Inteligex is focused on developing innovative stem cell-based therapeutics aimed at restoring function in patients with spinal cord injuries, a condition currently lacking effective therapies. The company specializes in novel stem cell technologies designed to treat both acute and chronic spinal cord injuries. By modifying the spinal microenvironment and providing regenerative therapeutic cells, Inteligex aims to replace essential cells lost due to injury. This approach offers the potential to enable healthcare providers to help patients regain lost functions and improve their quality of life. If successful, Inteligex could become a pioneer in delivering treatments for spinal cord injuries and other central nervous system diseases, impacting hundreds of thousands of patients globally.

CerebTalk is a company focused on developing innovative brain-computer interfaces (BCIs) to assist individuals with severe motor impairments, such as those affected by amyotrophic lateral sclerosis, spinal cord injuries, strokes, cerebral palsy, and non-verbal autism. The company offers a communication tool that enables users with limited voluntary movements to interact more effectively. In addition to its primary focus on aiding individuals with disabilities, CerebTalk also creates wireless in-ear EEG earphones that work in conjunction with an application. This technology allows users to monitor aspects of their physical and mental wellness, including stress levels, sleep quality, and physical activity, thereby enhancing overall well-being.

Epineuron Technologies, Inc. is a medical device company based in Hamilton, Canada, established in 2016. It specializes in developing innovative treatment strategies for peripheral nerve injuries through bioelectronic medicine. The company focuses on creating a suite of surgical solutions aimed at enhancing the repair and regeneration of peripheral nerves. Epineuron's flagship product is an electroceutical device that delivers targeted electrical stimulation to accelerate the natural healing processes of injured nerves. By leveraging this technology, Epineuron aims to set a new standard of care in the field of nerve injury treatment, aspiring to become a leader in bioelectronic nerve care.

NeuroQore, Inc. is a Canadian company based in Ottawa, founded in 2012, that specializes in developing innovative neuromodulation treatment systems aimed at addressing treatment-resistant depression and related neurobehavioral conditions. The company's flagship product is a monophasic repetitive transcranial magnetic stimulation system that utilizes a unique semiconductor switch to emit a novel magnetic pulse. This technology is designed to help patients overcome challenges associated with major depressive disorder and suicidality, ultimately improving their quality of life. NeuroQore collaborates with leading universities and research clinics globally, reflecting its commitment to advancing the field of neuromodulation and transforming the lives of those affected by these debilitating disorders.

Zentrela Inc. is a neurotechnology company based in Hamilton, Canada, established in 2015. It specializes in developing advanced EEG systems aimed at enhancing safety in environments where cognitive impairment due to substances like cannabis can lead to accidents. Zentrela's flagship product, the Zentrela wellness system, is a wearable device that employs artificial intelligence to analyze brain activity, helping to prevent incidents while driving or working. The company targets the legalized cannabis industry, utilizing its proprietary technology to create a comprehensive database of consumer experiences linked to various cannabis products. This innovative approach seeks to shift the focus in the cannabis sector from plant-based data to consumer experience data, ultimately transforming product development, marketing, and sales strategies within the industry.

Stabilo Medical is a manufacturer of medical equipment and wearable devices focused on enhancing rehabilitation outcomes for stroke victims. The company has developed an innovative wearable vest designed to improve the rate and quality of rehabilitation by providing repetitive exercise to core muscles. This device features sensors that detect when a patient is slouched and assists them in returning to an upright position, allowing for safe and effective exercise without the need for a therapist. Stabilo Medical also offers a range of products related to disability and death, and inquiries about their offerings can be made through an online form on their website.

QurCan Therapeutics develops nanotechnology-based drug delivery platforms for precision medicine in solid-tumor cancer therapy. Their platform efficiently delivers drugs, antibodies, and RNA to hard-to-reach tumors, including the brain, enhancing therapeutic outcomes.

TruReach Health is a developer of self-help applications focused on mental wellness. The company offers a platform that provides users with accessible cognitive behavioral therapy (CBT) lessons and tools. Through its application, users can engage in step-by-step exercises and track their symptoms, allowing them to monitor their mental health condition. This enables individuals to receive support for their mental wellness in a user-friendly format, bridging the gap until they can consult with a qualified psychologist.

Founded in 2017, Curv Health is a virtual clinic that empowers healthcare providers to establish and manage their own practices. It offers a platform connecting patients with registered professionals, including physiotherapists, dietitians, psychotherapists, and counselors, focusing on mental health and performance coaching.

Give your patient’s family the support they deserve, so that you can focus on providing the best comprehensive care to your patient.Supports Health will improve loved ones outcomes, reduce re-admittance rates and helps families feel cared for.

Cerebian develops a brain-computer interface-based operating system that enables users to interact with electronic devices using brainwaves. This innovative technology facilitates communication and rehabilitation, particularly benefiting stroke patients by allowing them to control electronics with their thoughts.

Welbi is a company focused on enhancing the quality of life for older adults residing in senior living communities. It offers a recreational platform that simplifies administrative processes, allowing staff to dedicate more time to engaging with residents. By providing personalized programming and real-time insights, Welbi enables these communities to create unique experiences tailored to the individual needs of residents. The platform equips resident experience teams with the tools necessary to develop a comprehensive understanding of their residents, fostering deeper connections and preventing social isolation. Through these innovations, Welbi aims to transform the care and engagement practices within senior living environments.

Steadiwear is a company focused on developing innovative solutions for individuals suffering from hand tremors, particularly those with Parkinson's disease. Its flagship product, the Steadi-One, is the world's first battery-free glove designed to intelligently reduce tremors. This lightweight and compact glove employs a smart fluid mechanism that provides resistance against hand tremors, allowing users to regain independence and enhance their quality of life. The Steadi-One is classified as a Class I medical device and has received FDA registration. It became available for pre-order in August 2019, with the first batch of units delivered in December 2019, followed by a full-scale launch planned for March 2020.

HiNT is developing a wearable point-of-care monitoring device that detects a stroke with EEG and alerts high-risk patients, Its care givers, and their medical support team when the patient is having a stroke.

KalGene Pharmaceuticals Inc. is a private biotechnology company based in Candiac, Canada, focused on developing precision medicine for the treatment of Alzheimer’s disease. Established in 2006, KalGene collaborates with leading clinician-scientists and academic institutions across North America and Europe. The company specializes in creating targeted therapeutics and companion diagnostics aimed at enhancing clinical outcomes and survival rates. Through personalized medicine, KalGene seeks to predict patient responses to specific therapies before treatment begins, enabling physicians to tailor interventions based on individual biological signatures and needs.

Sound Options Tinnitus Treatments Inc. is a health technology company based in Ancaster, Canada, specializing in the development of software for tinnitus management. Founded in 2012, the company offers clinically tested, individually tailored sound therapy designed to alleviate the symptoms of tinnitus, a challenging hearing disorder that affects approximately ten percent of the population. Utilizing advanced computational neuroscience and tinnitus research, the company's software creates customized treatment plans based on each client's audiogram and tinnitus profile. The effectiveness of Sound Options' approach has been validated through studies conducted at McMaster University. The company has also formed partnerships with various independent and franchised hearing clinics across Canada to enhance accessibility for tinnitus patients and hearing healthcare professionals.