E12 Venture Capital

First Resonance, Inc. is a manufacturing software company based in Los Angeles, California, founded in 2018. The firm focuses on developing a factory operating system that enhances day-to-day operations for modern manufacturers. Its platform enables engineers to manage, execute, analyze, and share hardware tests, supporting the product development cycle from prototype to full-scale production. By providing tools to track parts and processes, First Resonance helps companies in various sectors, including aviation, energy, and automation, to streamline their manufacturing processes and quickly identify bottlenecks. The system ultimately facilitates rapid iterations and improved time-to-market outcomes, offering decision-makers immediate insights into their operations.

One.bio is an emerging biotechnology company spun out from UC Davis, specializing in the development of naturally-derived oligosaccharides for food, agriculture, and biopharmaceutical applications. Utilizing proprietary technology, the company creates novel oligosaccharides from natural products aimed at positively influencing the microbiome and enhancing immune function. One.bio's innovative ingredients provide clients with access to prebiotics and therapies that support both human and animal health, positioning the company as a significant player in the fields of nutrition and longevity.

Unspun, Inc. is a digital apparel company based in San Francisco, California, founded in 2015. It specializes in creating custom jeans tailored to individual consumers using advanced body scanning technology, fit algorithms, and additive manufacturing. The company aims to address environmental challenges by minimizing pattern-cutting waste and unsold inventory, thus contributing to a reduction in global carbon emissions. Unspun's innovative approach enables on-demand production of jeans in under ten minutes, utilizing localized manufacturing processes designed to be zero-waste. Its technology has gained recognition, including being named one of TIME's Best Inventions of 2019, and supports a B2B platform that facilitates digital customization for major apparel brands.

Ciba Health is a personalized digital therapeutics and virtual care platform that focuses on treating and reversing chronic conditions through a precision health approach. The company empowers patients by promoting self-care and offering a patient-centered, root-cause methodology. Ciba Health emphasizes a value-based care delivery model that integrates full-spectrum care, providing convenient access to multidisciplinary teams. By leveraging advanced technology, it implements individualized treatment plans that address the physical, mental, and lifestyle needs of patients, fostering improvements in overall well-being.