Amgen

Quantinuum is a leading quantum computing company focused on advancing quantum computers and developing software solutions for various applications, including materials discovery, cybersecurity, chemistry, finance, and optimization. With a team of nearly 500 professionals, including over 370 scientists and engineers, Quantinuum aims to drive the global quantum computing revolution. The company offers an open-access, architecture-independent quantum software stack and a development platform that allows researchers and developers to work seamlessly across different platforms. This approach enables the tackling of complex challenges and fosters innovation in next-generation quantum artificial intelligence.

Generate Biomedicines, Inc. is a biotechnology company based in Cambridge, Massachusetts, focused on developing innovative therapies through its unique platform. The company specializes in Generative Biology, a machine learning-driven approach that analyzes known proteins to understand the relationship between genetic sequences, protein structure, and function. This enables the creation of novel therapeutic proteins, including antibodies, enzymes, and receptors, which are designed to interact specifically and effectively with various therapeutic targets. Founded in 2018 and rebranded from Generate Biologics in 2020, Generate Biomedicines aims to streamline the drug discovery process by generating new biological molecules with significant therapeutic potential.

Neumora Therapeutics is a clinical-stage biotechnology company focused on developing precision medicines for brain diseases by combining data science with neuroscience. Founded to address the global brain disease crisis, Neumora takes an innovative approach to treatment development. The company has established a robust therapeutic pipeline that includes seven clinical and preclinical neuroscience programs targeting novel mechanisms of action for various underserved neuropsychiatric and neurodegenerative disorders. Neumora plans to advance its pipeline further by initiating multiple clinical trials across its programs in the upcoming 12 to 18 months.

ChemoCentryx, Inc. is a clinical-stage biopharmaceutical company based in Mountain View, California, focused on developing and commercializing innovative medications for inflammatory disorders, autoimmune diseases, and cancer. The company's lead drug candidate, Avacopan, is an orally-administered complement inhibitor currently undergoing Phase III trials for anti-neutrophil cytoplasmic auto-antibody-associated vasculitis and a Phase IIb trial for moderate-to-severe hidradenitis suppurativa and complement 3 glomerulopathy. Additionally, ChemoCentryx is advancing other drug candidates, including CCX140, an inhibitor targeting the CCR2 chemokine receptor, which has completed Phase II trials for diabetic nephropathy and is being developed for focal segmental glomerulosclerosis; CCX507, a second-generation CCR9 inhibitor that has completed Phase I trials; and CCX872, a selective CCR2 inhibitor currently in Phase Ib trials for stage 3 and 4 pancreatic cancer. ChemoCentryx aims to address the underlying immune system dysfunction associated with various conditions through its targeted therapeutics.

Accure Health is a privately held precision medicine company dedicated to developing AI-powered solutions that utilize patients' biomarker profiles. The company aims to enhance the delivery of precision therapies by ensuring that treatments are directed to the appropriate cells for the right patients. Accure Health's patented technologies integrate advanced protein design, an automated biomarker device, and a scalable, food-based production system. This innovative approach focuses on improving the targeted delivery of RNA and protein therapeutics, thereby facilitating access to more effective treatments tailored to individual patient needs.

Neumora Therapeutics is a clinical-stage biotechnology company focused on developing precision medicines for brain diseases by combining data science with neuroscience. Founded to address the global brain disease crisis, Neumora takes an innovative approach to treatment development. The company has established a robust therapeutic pipeline that includes seven clinical and preclinical neuroscience programs targeting novel mechanisms of action for various underserved neuropsychiatric and neurodegenerative disorders. Neumora plans to advance its pipeline further by initiating multiple clinical trials across its programs in the upcoming 12 to 18 months.

TeneoBio, Inc. is a biotechnology company focused on developing human heavy chain antibodies, known as UniAbs, for therapeutic applications in cancer, autoimmunity, and infectious diseases. Since its founding in 2009 and headquartered in Menlo Park, California, the company has advanced several products targeting conditions such as multiple myeloma, prostate cancer, immune disorders, and AIDS. TeneoBio utilizes its proprietary antibody discovery platform, which includes genetically engineered animals and advanced technologies like next-generation sequencing and bioinformatics. This platform enables the rapid identification of unique binding molecules, facilitating the development of bispecific and trispecific antibodies as well as immune checkpoint inhibitors. The company aims to enhance patients' immune responses to overcome various diseases and disorders.

Rodeo Therapeutics is a drug development company focused on novel enzyme target and biological pathway that play a critical role in tissue repair and regeneration. Rodeo’s initial goal is to develop novel small molecules therapies for the treatment of inflammatory bowel disease and the promotion of blood cell reconstitution following bone marrow transplant.

Five Prime Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, specializing in the discovery and development of innovative protein therapeutics. The company is advancing several product candidates, including Bemarituzumab, an antibody targeting fibroblast growth factor receptor 2b (FGFR2b), currently in Phase 3 clinical trials for gastric and gastroesophageal junction cancer. Other candidates include FPA150, a CD8 T cell checkpoint inhibitor in Phase 1a/1b trials for various cancers, and FPT155, a soluble CD80 fusion protein enhancing T cell co-stimulation, also in Phase 1a/1b trials. Additionally, Cabiralizumab, which inhibits colony stimulating factor-1 receptor, is undergoing Phase Ia/Ib trials in combination with other therapies. The company employs its ProScreen Engine to systematically screen all relevant human proteins, enabling rapid and high-quality therapeutic development. Five Prime Therapeutics has established collaborations and license agreements with several pharmaceutical companies, enhancing its research and development capabilities. Founded in 2001, the company continues to focus on advancing novel therapies for challenging cancer indications.

Science 37, Inc. is a technology-enabled clinical trial company based in Los Angeles, California, focused on advancing biomedical research through innovative, patient-centric models. The company has developed NORA, a cloud-based mobile research platform that facilitates end-to-end networked clinical trial services, allowing researchers to interact with patients and mobile nurses remotely via videos, photographs, and surveys. By utilizing a decentralized approach, Science 37 enhances patient engagement and access, making it possible to reach populations typically underserved by traditional trial methods. The company operates an extensive in-house network of telemedicine investigators and home-health nurses, enabling it to conduct a significant number of virtual interventional trials efficiently. Science 37 serves a diverse clientele, including pharmaceutical companies, device manufacturers, universities, and biotech firms, thereby contributing to the acceleration of clinical research and the development of new treatments.

Keck Graduate Institute (KGI) is part of the prestigious Keck is one of the few graduate schools exclusively dedicated to the study of biosciences. The school’s graduate programs blend academics with business-oriented approaches to the field.

Otezla® is a prescription medicine approved for the treatment of patients with moderate

BeiGene, Ltd. is a global biotechnology company founded in 2010, focused on discovering and developing innovative oncology treatments to improve accessibility and affordability for cancer patients worldwide. Headquartered in Beijing, the company operates in the U.S., China, and internationally, employing over 9,200 individuals and housing one of the largest oncology research teams globally. BeiGene's commercial products include BRUKINSA, a BTK inhibitor for blood cancers, and Tislelizumab, an anti-PD-1 antibody, which is under regulatory review in the U.S. and EU for advanced esophageal cancer. The company's extensive pipeline targets various malignancies, including acute myeloid leukemia, multiple myeloma, and solid tumors, with potential to address numerous cancer types. In addition to its product portfolio, BeiGene sponsors initiatives to support the broader needs of oncology patients, such as mental health awareness programs. The company has established collaborations with several biotechnology and pharmaceutical firms to enhance its research and development capabilities.

Nuevolution is a small molecule lead discovery company founded in 2001 and based in Copenhagen, Denmark. The company has developed Chemetics®, a patented hybrid technology that combines wet chemistry and molecular biology to accelerate drug discovery. This platform facilitates the rapid synthesis and DNA-tagging of over 1 billion diverse small molecule compounds, allowing for efficient screening and identification of potent drug leads. Nuevolution partners with pharmaceutical and biotechnology companies, having established agreements with major firms such as Merck, GlaxoSmithKline, and Novartis. The company is also involved in a joint venture with EpiTherapeutics and ExpreS2ion Biotechnologies to develop small molecule drugs targeting epigenetic factors, supported by a project budget from the Danish High Technology Fund. Nuevolution focuses on developing treatments for oncology and inflammatory diseases and also provides contract research services, generating revenue from multiple countries, including Denmark, Sweden, and the USA. The company is privately owned by several key Scandinavian investors.

Oxford Nanopore Technologies is a biotechnology company specializing in nanopore-based sequencing technology for analyzing DNA, RNA, proteins, and small molecules. Its diverse product line includes the portable MinION device, the benchtop PromethION, the GridION system, and Flongle, which caters to on-demand sequencing needs. The technology enables real-time data streaming and is applicable across various fields such as human genomics, cancer research, microbiology, plant science, and environmental studies. Additionally, Oxford Nanopore's products support rapid and accessible molecular analysis, making them suitable for both laboratory and field use. The company's innovations are backed by a robust patent portfolio and are utilized in over 80 countries, addressing needs in healthcare, agriculture, and education. Founded in 2005 and headquartered in Oxford, United Kingdom, Oxford Nanopore also maintains offices in several other countries, enhancing its global reach in advancing genomic research and applications.

immatics is a biopharmaceutical company focused on the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors. The company's customized Adoptive Cell Therapies (ACTengine) and antibody-like TCR Bispecifics are the two main product classes in the pipeline (TCER). With a focus on particularly difficult-to-treat solid malignancies, each therapy modality has unique characteristics to create the desired therapeutic impact for patients at various disease stages and with various types of tumors. immatics biotechnologies was established in 2000 by Hans Rammensee, Harpreet Singh, and Steffen Walter in Tübingen, Baden-Wurttemberg.

Darmiyan has developed a novel, proprietary, patent-protected technology called The Virtual Microscope (Software Algorithm). Using a non-invasive routine clinical brain MRI scan, The Virtual Microscope technology looks into the human brain and localizes and quantifies cell distortion (neurodegeneration) in every voxel of brain MRI generating new brain maps. The first clinical product of this technology is BrainSee, an AI-powered algorithm that has completed a successful third-party validation in the US and Canada establishing a remarkable accuracy and consistency for prognosis of mild cognitive impairment. It is built on over 40 years of cutting-edge neuroscience research combined with advanced medical image analysis and AI, and has received official approval from the late Prof. Paul Greengard, Nobel Laureate in Physiology/ Medicine 2000.

immatics is a biopharmaceutical company focused on the discovery of true targets for cancer immunotherapies with the development of the right T cell receptors. The company's customized Adoptive Cell Therapies (ACTengine) and antibody-like TCR Bispecifics are the two main product classes in the pipeline (TCER). With a focus on particularly difficult-to-treat solid malignancies, each therapy modality has unique characteristics to create the desired therapeutic impact for patients at various disease stages and with various types of tumors. immatics biotechnologies was established in 2000 by Hans Rammensee, Harpreet Singh, and Steffen Walter in Tübingen, Baden-Wurttemberg.

SiteOne Therapeutics is a San Francisco-based company focused on developing innovative therapeutics and diagnostics for the treatment of acute and chronic pain. The company aims to address the limitations of existing pain management therapies, such as non-steroidal anti-inflammatory drugs (NSAIDs) and opioids, by creating safer and more effective alternatives. Their lead candidates are highly selective inhibitors of the voltage-gated sodium ion channel Naᵥ1.7, which is crucial in the generation and conduction of pain signals. By targeting this channel, SiteOne Therapeutics seeks to provide healthcare professionals with advanced treatment options for neuropathic pain, ultimately improving patient outcomes and efficiency in pain management.

Unilife is a U.S-based medical device and technology company that designs, develops, manufactures and supplies innovative, differentiated delivery systems for injectable drugs and vaccines.

In April 2010, Medigene assigned its development program of oncolytic (cancer-killing) herpes simplex viruses (oHSV), to Catherex, Inc.

Dezima Pharma B.V., founded in 2012 and based in Naarden, the Netherlands, focuses on developing protein-based compounds aimed at treating cardiovascular diseases associated with dyslipidemia. The company is known for its innovative approach in creating a cholesteryl ester transfer protein inhibitor, which serves as a pharmacological therapy to reduce low-density lipoprotein cholesterol levels. By lowering these cholesterol levels, Dezima Pharma aims to provide clinicians with effective treatment options for patients suffering from dyslipidemia and related cardiovascular conditions.

Onyx Pharmaceuticals is a biopharmaceutical company committed to improving the lives of people with cancer. Their lead product is Nexavar (sorafenib), a novel, oral multiple kinase inhibitor that targets proteins involved in both tumor cell proliferation and angiogenesis.

DeCODE Genetics is a biopharmaceutical company that develops and offers diagnostic tests for variants in genes. DeCODE was established to identify human genes associated with common diseases using population studies, and apply the knowledge gained to guide the development of candidate drugs. The company has discovered key genetic risk factors for many common diseases ranging from cardiovascular disease to cancer. DeCODE Genetics was founded in 1996 and is based in Reykjavik, Iceland.

MN is the leading supplier of pharmaceuticals to hospitals in Turkey and garnered sales of about $200 million last year, according to the statement. It was the first Turkish pharmaceutical company to win a license from the Food and Drug Administration to sell products in the U.S.

KAI Pharmaceuticals is a drug discovery and development company with multiple, novel clinical-stage programs in the areas of cardiovascular disease, kidney disease and pain. KAI lead product candidate, KAI-9803, is currently in a Phase 2b study (PROTECTION AMI) designed to assess the effect of KAI-9803 on reducing myocardial injury in heart attack patients. KAI second core program, KAI-4169 for the treatment of secondary hyperparathyroidism (SHPT) in kidney disease patients, is expected to enter human clinical trials in 2010. KAI also has an ongoing pain program, KAI-1678, which is currently in Phase 2a testing.

Micromet is a biotechnology company focused on the research, development and commercialization of novel biological products for the treatment and control of cancer. Their lead product candidate, Canvaxin, is one of a new class of products being developed in the area of specific active immunotherapy, also known as therapeutic cancer vaccines.

Bergamo facilitates access and provides treatments in key therapeutic fields like onco-hematology, general medicine, and hospital segment.

Laboratorio Quimico Farmaceutico Bergamo is operates as a pharmaceutical company.

BioVex is a biotechnology company dedicated to developing and commercializing biological therapies for cancer treatment and the prevention of infectious diseases. Its primary focus is OncoVEXGM-CSF, an oncolytic vaccine that selectively targets and destroys cancer cells while sparing surrounding healthy tissue. This vaccine operates by replicating within solid tumors, leading to cancer cell death, and also stimulates a robust systemic immune response against tumors. OncoVEXGM-CSF has undergone clinical testing in over 110 patients across various solid tumors, including melanoma, head and neck cancer, breast cancer, and pancreatic cancer. The treatment has demonstrated significant efficacy, routinely eliminating tumors at the injection site and achieving overall disease responses during Phase II trials, with no reported recurrences of resolved tumors. Additionally, BioVex is developing ImmunoVEXHSV2, a vaccine aimed at preventing genital herpes.

Alantos Pharmaceuticals is a biopharmaceutical company focused on the discovery and development of small molecule drugs targeting conditions such as osteoarthritis, inflammation, and type II diabetes. Established in 2002 and located in Cambridge, Massachusetts, the company specializes in innovative therapeutic approaches, including Dipeptidyl and Peptidase IV inhibitors. In addition to its core areas, Alantos explores various tissue remodeling pathways to address a range of medical issues, including rheumatoid arthritis, liver fibrosis, cardiovascular conditions, chronic wound healing, and cancer.

Ilypsa is a company focused on discovering and developing pharmaceutical products for renal care, specifically targeting complications associated with chronic kidney diseases. Established in 2002 and based in Santa Clara, California, Ilypsa specializes in creating non-absorbed polymeric compounds that act as binders for phosphate and potassium. These compounds work by binding to phosphorus in the digestive tract, preventing its absorption into the body and thereby helping patients manage high blood levels of phosphorus, a condition known as hyperphosphatemia. The company's innovations are aimed at improving the quality of life for individuals suffering from kidney-related health issues.

Avidia, Inc. is a biopharmaceutical company based in Mountain View, California, that focuses on the discovery and development of therapeutic proteins. Founded in 2003, the company specializes in creating Avimer therapeutic proteins designed to treat a range of conditions, including autoimmunity, inflammation, oncology, and neurology. Avidia aims to innovate in the field of protein therapeutics to address significant medical needs across these therapeutic areas.

Abgenix is a biopharmaceutical company engaged in the discovery, development, and manufacture of human therapeutic antibodies for the treatment of various disease conditions such as cancer, inflammation, and metabolic disease. Its antibody therapeutic product candidates, which are in clinical trials include Panitumumab (ABX-EGF), a human antibody therapeutic product candidate directed against the epidermal growth factor receptor and a candidate for the treatment of various solid tumors. It also includes ABX-10241 (ABX-PTH), which isa fully human antibody therapeutic product candidate directed against parathyroid hormone for the treatment of a secondary hyper-para-thyroidism. Abgenix was established in 1996 and is headquartered in Fremont, California. It currently operates as a subsidiary of Amgen, Inc.

Tularik is a drug discovery and development company based in South San Francisco, California, founded in 1991 by David Goeddel, Steve McKnight, and Robert Tjian. The company focuses on creating orally available medicines that influence gene expression and is recognized as a pioneer in the field of cell signaling. Tularik's research and development efforts primarily target three key areas: inflammation, metabolic diseases, and oncology. The company's portfolio includes programs addressing a range of health issues, such as cancer, cytomegalovirus, diabetes, obesity, immune disorders, and hypercholesterolemia, as well as targeting orphan nuclear receptors. In 2004, Tularik was acquired by Amgen for $1.3 billion.

Immunex Corporation is a biopharmaceutical company that specializes in the development, manufacturing, and marketing of therapeutic products aimed at treating cancer, infectious diseases, and autoimmune disorders. Founded in 1981 and based in Seattle, Washington, the company is known for its products such as Enbrel, used for rheumatoid arthritis; Novantrone, for acute nonlymphocytic leukemia and prostate cancer pain; and Leukine, which assists bone marrow transplant patients. Immunex's therapeutic offerings primarily consist of immune system proteins that function as hormones within the body. The company also had a strategic alliance with American Home Products before it was acquired by Amgen, Inc. in 2002.

Filgrastim and pegfilgrastim are a supportive part of treatment for many patients receiving cancer chemotherapy. Some cancer drugs, in addition to attacking the cancer, destroy the patient's white blood cells, which are extremely important in fighting infection. Consequently, these patients are prone to developing severe, and even life-threatening, infections. Filgrastim and pegfilgrastim restore the number of white blood cells and thus improve their ability to kill infecting micro-organisms.

A company that specializes in discovering small molecules in the field of protein kinase inhibition.

Synergen offers revenue cycle management optimization solutions, consulting services and analytics to the healthcare industry. It utilizes technology, analytics, and expertise to help partners maximize and realize their organization’s full revenue potential. The company is driven by a mission to achieve quality outcomes with high economic value. Since its foundation, Synergen has grown exponentially while adding value to its clients. It has expanded its expertise to diverse specialties and large enterprise clients in revenue cycle management and analytics. Synergen was founded in 2011 and is headquartered in Dallas, Texas.