Altis Biosystems
Altis Biosystems, LLC is a biotechnology company specializing in the development of innovative stem cell technologies aimed at enhancing research in human biology. Established in 2015 and based in Chapel Hill, North Carolina, the company has created a patent-pending system known as RepliGut, which effectively recreates the human intestinal epithelium and colonic epithelium. This advanced technology enables the generation of a layer of human or animal intestinal stem and differentiated cells from both the small and large intestines. Altis Biosystems' products are primarily utilized in preclinical studies for disease modeling, precision medicine, microbiome research, and compound screening, serving the needs of pharmaceutical and biotechnology companies. By utilizing normal human intestinal tissue, the company aims to improve drug development processes while minimizing reliance on animal testing.
Plakous Therapeutics
Grant in 2022
Plakous Therapeutics, based in Winston-Salem, North Carolina, specializes in producing restorative and regenerative healing products derived from post-delivery human placentas. Founded in 2016 by Seth Tomblyn and Scott Washburn, the company manufactures biotherapeutics, including its flagship product, Protego-PD, an orally delivered acellular therapy. Plakous Therapeutics focuses on utilizing placental cytokines and growth factors to create allografts that promote and support the body's natural healing processes. By enhancing the functionality of the amniotic membrane as a drug delivery device, the company aims to provide healthcare providers and patients with effective therapeutic options grounded in scientific research and clinical evidence.
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