Alafi Capital

Alafi Capital Company LLC is a venture capital firm specializing in early and mid stage investments. The firm seeks to invest in healthcare with a focus on product oriented biotechnology, life science technologies, imaging and diagnostics, and medical devices sectors. It targets companies based in the United States and Europe. Alafi Capital Company LLC is headquartered in Berkeley, California with an additional office in San Francisco, California.

Moshe Alafi

General Partner

Christopher (Chris) Alafi

Managing Partner

Bill Weiss

CFO

17 past transactions

Leegur Oy

Venture Round in 2002
Leegur Oy develops real time adaptation software tools for mobile and fixed Internet services. The company also offers planning, implementation, and customer support services.
Direct Conversion provides detectors into imaging systems that are used across the globe
Direct Conversion provides detectors into imaging systems that are used across the globe

Bolt Threads Inc.

Series C in 2016
Bolt is a materials company that invents and scales materials that put the planet on a path towards a better future. Biofabricated silk fibers MicrosilkTM - based on proteins found in nature, produced using Bolt Threads proprietary technology and revolutionary bioengineering concepts. Next-generation of performance fibers, fabrics and luxury products that represent cutting-edge technology in science, while raising the bar for quality, performance, and design.

Natera

Series B in 2009
Natera is driven by a passion for elevating the science and utility of prenatal testing. The advent of the Information Age has created a paradigm shift in the fields of computing and informatics. Surprisingly, medical diagnostics have been slow to integrate these advances into genetic testing.
Direct Conversion provides detectors into imaging systems that are used across the globe

Assurex Health

Series D in 2015
Assurex Health is a personalized medicine company dedicated to helping clinicians determine the right medication for individual patients with medical conditions. Assurex Health’s proprietary Genesight® technology is based on pharmacogenomics – the study of the genetic factors that influence an individual’s response to drug treatments – as well as evidence-based medicine and clinical pharmacology.

Arcxis Biotechnologies

Series B in 2009
Arcxis Biotechnologies is focused on developing elegant, integrated and compact solutions to molecular diagnostic challenges. From proprietary microfluidics to advanced detection methods; streamlined sample preparation to comprehensive automation technology, we are in the business of making molecular methods more reliable, robust and accessible.

Hybrigenics

Series B in 2001
Hybrigenics Pharma is a bio-pharmaceutical company with a focus on research and development of new targets and therapies against cancer.Hybrigenics Pharma has stopped the development of inecalcitol, a vitamin D receptor agonist.Hybrigenics Pharma's research program investigates the action of enzymes called Deubiquitinating Enzymes (DUBs) in the recycling of onco-proteins and the potential activity of proprietary patented DUB inhibitors against various cancer indications.

Stereotaxis, Inc.

Venture Round in 2003
Stereotaxis focuses on the development of robotic cardiology instrument navigation systems designed to enhance the treatment of arrhythmias and coronary disease, as well as information management solutions for the interventional lab. With over 100 patents for use in a hospital's interventional surgical suite, Stereotaxis helps physicians around the world provide unsurpassed patient care with robotic precision and safety, improved lab efficiency and productivity, and enhanced collaboration of life-saving information. Stereotaxis' core technologies are the Niobe® ES Remote Magnetic Navigation system, the Odyssey™ portfolio of lab optimization, networking and patient information management systems and the Vdrive™ Robotic Mechanical Navigation system and consumables.
Coley Pharmaceutical Group operates as a biopharmaceutical company developing therapeutics and drug candidates that direct the human immune system to fight cancers, asthma and allergy, autoimmune disorders, and to enhance the effectiveness of vaccines. The company was formerly known as CpG ImmunoPharmaceuticals, Inc. and in August 2000 it changed its name to Coley Pharmaceutical Group, Inc. The company was founded in 1997 and is based in Wellesley, Massachusetts. As of December 28, 2007, Coley Pharmaceutical Group, Inc. operates as a subsidiary of Pfizer Inc.

Direct Conversion AB (publ)

Venture Round in 2002
Direct Conversion provides detectors into imaging systems that are used across the globe

Isto Technologies

Series E in 2007
ISTO Technologies, Inc., an orthobiologics company, develops biologic products to regenerate and restore function to damaged cartilage and bone. It offers InQu, a resorbable bone graft extender and substitute; NuQu, a cell-based injectable therapy for disc regeneration; and DeNovo ET, an engineered cartilage implant for the repair and regeneration of knee cartilage. The company provides its products through distributors. ISTO Technologies, Inc. was founded in 1997 and is based in St. Louis, Missouri.

Kreatech Diagnostics

Series B in 2010
Kreatech Holding BV is a molecular diagnostics company focused on the development and commercialization of innovative detection products. These are used for diagnostic and research applications in the life sciences and healthcare industry.

Bolt Threads Inc.

Series B in 2015
Bolt is a materials company that invents and scales materials that put the planet on a path towards a better future. Biofabricated silk fibers MicrosilkTM - based on proteins found in nature, produced using Bolt Threads proprietary technology and revolutionary bioengineering concepts. Next-generation of performance fibers, fabrics and luxury products that represent cutting-edge technology in science, while raising the bar for quality, performance, and design.

Resolve BioSciences GmbH

Private Placement in 2020
Resolve BioSciences GmbH designs and develops a spatial multiomics analysis platform which helps in the view of single-cell spatial biology. Its platform provides full spatial highest-resolution view of subcellular gene expression activity. Resolve BioSciences GmbH was founded in 2016 and is based in Monheim am Rhein, Germany.

Kreatech Diagnostics

Venture Round in 2009
Kreatech Holding BV is a molecular diagnostics company focused on the development and commercialization of innovative detection products. These are used for diagnostic and research applications in the life sciences and healthcare industry.