Bill & Melinda Gates Foundation

The Bill & Melinda Gates Foundation is a grant-making foundation that supports initiatives in education, world health and population, and community giving in the Pacific Northwest. In its local region, the foundation promotes strategies and programs that help low income families.The Bill & Melinda Gates Foundation was co-founded by Bill Gates and Melinda Gates in 2000 and is based in Seattle, Washington, with regional offices in Washington, D.C.; New Delhi, India; Beijing, China; and London, United Kingdom. Its trustees are Bill and Melinda Gates, and Warren Buffett.

Past deals in Healthcare and Biotech

Kallyope

Grant in 2023
Kallyope is pioneering the science and understanding of gut and gut-brain biology to create medicines that transform human health. Based in New York City, Kallyope is home to some of the world’s most intrepid scientific minds from the world’s top institutions, working alongside a seasoned team with a proven track record of success in drug discovery and development. Kallyope leverages a unique combination of leading technologies and a foundation of internally-developed capabilities to bring fundamentally new solutions to some of the most pressing unmet needs in human health – from diabetes, obesity, and gut disorders to inflammatory disease, migraine, allergies, and more.

Vir

Grant in 2023
Vir Biotechnology is a commercial-stage immunology company developing therapeutic products to treat and prevent serious infectious diseases. The company brings together cutting-edge innovations with scientific expertise and management. It seeks to take a new approach, using breakthroughs in immune programming to manipulate pathogen-host interactions. Vir Biotechnology also focused on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. The company four current technology platforms are designed to, either individually or in combination, stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Their vision is that one day, diseases like hepatitis B, influenza A, HIV, and tuberculosis become a thing of the past.

Audere

Grant in 2023
Audere is a digital health nonprofit developing software to improve global health in underserved communities.

Smart Immune

Grant in 2023
Smart Immune is a clinical-stage biotechnology company focused on developing the next generation of hematopoietic stem cell-based biotherapies to change the prognosis and life quality of patients with devastating diseases. The company's first cell therapy program is based on T cell progenitors or ProTcellsTM (CD7+/CD34-; CD5- cells) curative power to enable a short, polyclonal, and safe post-transplantation immune recovery. This program be completed by integrative developments from targeted conditioning to gene therapy and genome editing enabling clinicians to access new-generation treatments for a wide variety of inherited blood disorders and blood cancers.

SpyBiotech

Grant in 2023
SpyBiotech Operators of a biotechnology platform intended to generate next-generation vaccines.The company's biotechnology platform develops bonding vaccines which are made from the proprietary protein superglue which is used to bond antigens to viruses and other particles to make vaccines, enabling medical institutions and research centers with a new and modified technology to develop vaccines which give better results in lesser time.

Sapient

Grant in 2022
Sapient enables the discovery of circulating small molecule biomarkers at unprecedented speed and scale. Leveraging next-generation mass spectrometry, biocomputational analysis, and large-scale human biology databases, its platform supports the rapid identification and validation of circulating biomarkers of health, disease, and drug response which are needed to align patients, disease biology, and specific therapies.
Yemaachi Biotechnology uses cutting-edge immunogenomics, bioinformatics, and artificial intelligence to accelerate the development of cancer detection and cure strategies for lowering the economic burden of cancer.
Aridis Pharmaceuticals discovers and develops anti-infectives to be used as add-on treatments to standard-of-care antibiotics. The company is utilizing its proprietary ʎPEXTM and MabIgX technology platforms to rapidly identify rare, potent antibody-producing B-cells from patients who have successfully overcome infection and to rapidly manufacture monoclonal antibodies (mAbs) for the therapeutic treatment of critical infections. These mAbs are already of human origin and functionally optimized for high potency by the donor's immune system; hence, they technically do not require genetic engineering or further optimization to achieve full functionality.
Particles for Humanity transforms early-stage medical technology into products for people living in low-resource settings. Its development plans include a portfolio of products for improving vaccination and reducing malnutrition. Its rigorous product development process is based on end-user input and is focused on financially sustainable product opportunities.

Evotec

Grant in 2021
Evotec is a drug discovery alliance and development partnership rapidly progressing innovative product approaches with pharmaceutical and biotechnology companies, academics, patient advocacy groups, and venture capitalists. Drug discovery solutions are provided in the form of fee-for-service work, integrated drug discovery alliances, development partnerships, licencing of innovative drug candidates, and consulting arrangements.

Elarex

Grant in 2021
Elarex is a Canadian healthcare technology company commercializing its proprietary PT120 formulation technology which has proven to stabilize biologicals (including live vaccines!) so that they are as effective when stored at 40C as if they had been stored at -80C.
Providence Therapeutics is a biotechnology company that develops a personalized mRNA cancer vaccine designed to treat advanced ovarian cancer. The company's vaccine identifies tumor mutations and elicits an immune response against the tumor cells, enabling users to treat themselves and live life to the fullest. It aims to provide safe and effective medicines for people suffering from diseases with unmet medical needs. Scott Leary, Eric Marcusson, and Bradley Sorenson established the company in Toronto, Ontario in 2015.

Schrödinger

Grant in 2021
Schrödinger develops a computational platform that facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas. Schrödinger is deeply committed to investing in the science and talent that drive its computational platform.

Brightseed

Grant in 2021
Brightseed is a pioneer in biosciences and artificial intelligence that illuminates nature to restore human health. Through Forager® A.I. and clinical evaluation, Brightseed helps companies gain the deepest insight into bioactives and their innovation potential. Forager A.I. accelerates bioactive discovery and biological validation from years to months – and is rapidly revealing new connections between nature and humanity. Brightseed partners with companies across the consumer health continuum to provide novel insights and science-backed health solutions. Bioactives are small molecule compounds produced by plants, fungi, and microbes that grow in and adapt to environments that present a wide range of challenges to their survival. Bioactives also benefit the health of humans – they are the enlivening caffeine in tea, the powerful antioxidant lycopene in tomatoes, and they inform active ingredients in medicines like Taxol, Aspirin, and Metformin, a first-line treatment for Type 2 diabetes, derived from the French lilac flower. Science has long known that bioactives are critical to human health, yet the vast majority remain unknown and uncharted. Brightseed’s A.I., Forager®, discovers bioactives in nature and maps them to human health outcomes at a rate and accuracy that was previously impossible.
Titan Pharmaceuticals, Inc. is a biopharmaceutical Company developing proprietary therapeutics primarily for the treatment of serious medical disorders. Titan’s principal asset is Probuphine®, the first slow-release implant formulation of buprenorphine hydrochloride (“buprenorphine”), designed to maintain a stable, round-the-clock blood level of the medicine in patients for up to six months following a single treatment. The outpatient treatment of opioid dependence with daily dosed sublingual buprenorphine formulations represents a $1.3 billion market in the U.S., and a seven day transdermal patch formulation of buprenorphine for the treatment of chronic pain was launched in the U.S. in 2011. This novel implant formulation is inserted subdermally in a patient’s upper arm providing continuous medication, and has the potential to enhance patient compliance to treatment, and limit diversion for illicit use and accidental exposure to the sublingual formulations. The New Drug Application (NDA) was submitted to the FDA in October, 2012 seeking approval for treatment of opioid dependence. In December 2012, Titan entered into a license agreement with Braeburn Pharmaceuticals Sprl (“Braeburn”) that grants Braeburn exclusive commercialization rights to Probuphine® in the United States and Canada. Titan received a non-refundable up-front license fee of $15.75 million and will receive a $50 million milestone payment upon the approval of the NDA by the FDA. Additionally, Titan will be eligible to receive up to $130 million upon achievement of specified sales milestones and up to $35 million in regulatory milestones in the event of future NDA submissions and approvals for additional indications, including chronic pain. Titan will receive tiered royalties on net sales of Probuphine ranging from the mid-teens to the low twenties. Probuphine is the first product to utilize ProNeura™, a novel, proprietary, long-term drug delivery technology. The ProNeura technology has the potential to be used in developing products for the treatment of other chronic conditions, such as Parkinson’s disease, where maintaining stable, round-the-clock blood levels of a drug can benefit the patient and improve medical outcomes. Finally, Titan is also entitled to royalty revenue of 8-10% of net sales of Fanapt® (iloperidone), an atypical antipsychotic compound being marketed in the U.S. for the treatment of schizophrenia by Novartis Pharma AG (“Novartis”) under a sub-license agreement based on a licensed U.S. patent that expires in October 2016 (does not include a possible six month pediatric extension). Substantially all of this future royalty revenue has been sold to Deerfield Management (“Deerfield”), a healthcare investment fund, in exchange for cash and debt considerations which have been used to advance the development of Probuphine and for general corporate purposes.

Biotalys

Grant in 2021
Biotalys is an Agricultural Technology (AgTech) company that employs its proprietary Agrobody technology platform to develop crop and food protection products. The company develops a new generation of protein-based biocontrol solutions, shaping the future of sustainable and safe food supply. Biotalys' unique protein-based biocontrols combine the high-performance characteristics of chemicals with the clean safety profile of biologicals, making them ideal crop protection agents for both pre- and post-harvest applications. It was incorporated in 2013 and is based in the Biotech hub in Ghent, Belgium.

Eleven Therapeutics

Grant in 2021
Eleven Therapeutics is a biotechnology company at the forefront of the artificial intelligence revolution in medicinal nucleic acids. The new generation of RNAi therapies is introduced by merging artificial intelligence, parallel functional testing, and combinatorial chemistry. SCSI-RNA is a programmable molecule that can be used to target any disease or biological target of interest.
Particles for Humanity transforms early-stage medical technology into products for people living in low-resource settings. Its development plans include a portfolio of products for improving vaccination and reducing malnutrition. Its rigorous product development process is based on end-user input and is focused on financially sustainable product opportunities.

Dare Bioscience

Grant in 2020
Daré Bioscience is a healthcare company committed to the development and commercialization of innovative products in women’s reproductive health.

Sapient

Grant in 2020
Sapient enables the discovery of circulating small molecule biomarkers at unprecedented speed and scale. Leveraging next-generation mass spectrometry, biocomputational analysis, and large-scale human biology databases, its platform supports the rapid identification and validation of circulating biomarkers of health, disease, and drug response which are needed to align patients, disease biology, and specific therapies.

E25Bio

Grant in 2020
E25Bio specializes in the development of rapid diagnostic tests for epidemic fever viruses. It is dedicated to preventing severe downstream health outcomes with the use of mobile, fast, real-time reporting to create unprecedented large datasets to guide informed and timely responses for the control of disease spread. The company was founded in 2018 and is headquartered in Cambridge, Massachusetts.

Dynavax Technologies

Grant in 2020
Dynavax is a commercial stage biopharmaceutical company developing and commercializing novel vaccines. The Company's first commercial product, HEPLISAV-B® [Hepatitis B Vaccine (Recombinant), Adjuvanted], is approved in the U.S. and the European Union for prevention of infection caused by all known subtypes of hepatitis B virus in adults age 18 years and older. Dynavax is also advancing CpG 1018TM adjuvant as a premier vaccine adjuvant through research collaborations and partnerships. Current collaborations are focused on adjuvanted vaccines for COVID-19, pertussis and universal influenza.
Particles for Humanity transforms early-stage medical technology into products for people living in low-resource settings. Its development plans include a portfolio of products for improving vaccination and reducing malnutrition. Its rigorous product development process is based on end-user input and is focused on financially sustainable product opportunities.

Immunocore

Series B in 2020
Immunocore is focused on the discovery and development of novel T cell receptor-based drugs to treat diseases with a high unmet need, including cancer and viral disease. The company’s expertise in engineering T Cell Receptors (TCRs) and linking them to an antibody fragment (scFv) known as anti-CD3, has led to its first product candidate, IMCgp100, entering clinical trials in patients with metastatic melanoma. The proprietary T Cell Receptor technology platform is well validated and can easily be manufactured for clinical and commercial supply in microbial systems. Immunocore is a biotechnology company that specializes in the development of TCR bispecific immunotherapies.

Biological Dynamics

Grant in 2020
Biological Dynamics, Inc. is a healthcare company committed to improving global health outcomes by detecting diseases in their earliest stages. The company's proprietary platform simplifies access to native-state biomarkers and nanoparticles, enabling multiomics applications. The company is focused on detecting cancers by applying its platform technology along with its machine learning capabilities. For more information, please visit www.biologicaldynamics.com and follow us at @BiodynSD on Twitter. It was founded in 2008 and is headquartered in San Diego, California.
Pendulum Systems is an AI company building the first intelligent supply chain planning platform. Pendulum AI predicts demand, optimizes supply, and puts assets on the map, all while continuously improving on its own. Our technology is the result of a decade of rigorous research and development and has been deployed across some of the most demanding environments on Earth. Today, Pendulum is at work for corporations and governments across six continents, driving margins and saving lives. In 2023, Macro-Eyes became Pendulum, shifting from an R&D focus to productization and commercial growth.

Almac Group

Grant in 2019
Almac Group is a prominent contract development and manufacturing organization based in Craigavon, United Kingdom, specializing in a comprehensive array of services for the pharmaceutical and biotech sectors. With over 40 years of organic growth, the company employs more than 4,500 skilled professionals and operates facilities in the UK, Ireland, the United States, and Asia. Almac Group's offerings encompass research and development, biomarker discovery and development, active pharmaceutical ingredient (API) manufacture, formulation development, clinical trial supply, and companion diagnostic development. The group also includes Almac Diagnostics, which focuses on biomarker discovery and validation, providing services such as bioinformatics solutions and genomic analyses. Additionally, Almac Discovery is dedicated to oncology, concentrating on innovative cancer treatment approaches during the discovery and preclinical stages. Through continuous investment in state-of-the-art technology and services, Almac Group supports clients throughout the entire biopharmaceutical product lifecycle, from preclinical development to commercialization.

RJH Biosciences

Grant in 2019
RJH Biosciences focus on development of transfection reagents and delivery agents for nucleic acids. The company distributes its products via its website and undertakes projects on new medical treatments.

Vedanta Biosciences

Series C in 2019
Vedanta Biosciences is a developer of immunotherapies designed to treat immune-mediated and infectious diseases. It includes a suite of proprietary assays to select pharmacologically potent strains, vast proprietary datasets from human interventional studies, and facilities for cGMP-compliant manufacturing of rationally defined bacterial consortia in powder form to help physicians have access to live bacteria drugs to treat autoimmune and inflammatory diseases easily.

BioNTech

Post in 2019
BioNTech is a next-generation immunotherapy company pioneering novel therapies for cancer and other serious diseases. It contains several classes of drugs, including mRNA-based drugs to encode antigens, neoantigens, cytokines, and antibodies; cell therapies; bispecific antibodies; and antibody-drug conjugates.

Lyndra Therapeutics

Grant in 2019
Lyndra Therapeutics is a company that develops medicines for long-term drug release in an oral dose form. The company is developing oral ultra-long-acting and sustained-release therapies for central nervous system (CNS) disorders for broad applicability across multiple therapeutic areas, including approved drugs, allowing the medical community to ensure improved medication adherence and health outcomes while also helping to lower healthcare costs.

Biological Dynamics

Grant in 2019
Biological Dynamics, Inc. is a healthcare company committed to improving global health outcomes by detecting diseases in their earliest stages. The company's proprietary platform simplifies access to native-state biomarkers and nanoparticles, enabling multiomics applications. The company is focused on detecting cancers by applying its platform technology along with its machine learning capabilities. For more information, please visit www.biologicaldynamics.com and follow us at @BiodynSD on Twitter. It was founded in 2008 and is headquartered in San Diego, California.
Integrated BioTherapeutics is a biotechnology company that focuses on discovering novel vaccines and therapeutics for emerging infectious diseases. Its antiviral pipeline includes unique pan-filovirus antibody candidates, vaccines, and a variety of other product candidates for emerging viruses.

Univercells

Grant in 2019
Univercells is a One-stop-shop for high-density low-cost biomanufacturing "end-to-end" solutions, with innovative engineering able to decrease the needs for investments of over 75% and the cost of goods of up to 90%. Univercells' technologies, aimed at low cost manufacturing of antibodies/proteins/vaccines, is based on single-use technologies, and chaining of three manufacturing steps into simulated continuous mode : cell culture under perfusion, clarification and capture.
Emory Investment Management is responsible for the asset allocation, investment management, and oversight of the more than $7 billion portfolio of diversified investments owned by Emory University and Emory Healthcare, along with their associated retirement plans and affiliated entities. Our leading-edge strategies produce superior long-term investment results, positioning the portfolio in a way that maintains purchasing power after spending and inflation, generates growth via generous returns, and enables Emory to be a commanding global university attracting top-flight students and faculty alike.

Qloudlab

Grant in 2019
Qloudlab specializes in innovative healthcare solutions, particularly through its development of Sceptre, the world's first touchscreen-based biosensor. This modular platform facilitates a wide range of diagnostic tests, including blood, urine, saliva, and skin analyses, all within a single mobile system. By integrating smartphone technology with healthcare and cloud computing, Qloudlab aims to streamline diagnostics at the Point-of-Care, making testing more accessible and efficient. The company's technology is designed to be cost-effective, enhancing the user experience for both patients and healthcare professionals. Through its advancements, Qloudlab is positioned to transform the diagnostics landscape, ensuring that essential health information is readily available and easily obtainable.

AbCellera

Grant in 2019
AbCellera is an antibody discovery and development engine that’s specifically designed to address the barriers of conventional discovery, finding the optimal clinical candidate with greater precision and speed, getting to the clinic – and patients – sooner. With the integrated AbCellera platform, our experts search a wide range of diverse antibodies to select the most effective and developable leads fast and set our partners up for enduring success. We have extensive experience forging partnerships with emerging biotechs and leading pharmaceutical companies. AbCellera leverages proprietary hardware, software, tools along with the latest data science, to operate as strategic partners and help develop optimized solutions faster for any program.

Schrödinger

Series E in 2019
Schrödinger develops a computational platform that facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas. Schrödinger is deeply committed to investing in the science and talent that drive its computational platform.
Particles for Humanity transforms early-stage medical technology into products for people living in low-resource settings. Its development plans include a portfolio of products for improving vaccination and reducing malnutrition. Its rigorous product development process is based on end-user input and is focused on financially sustainable product opportunities.

Vedanta Biosciences

Series C in 2018
Vedanta Biosciences is a developer of immunotherapies designed to treat immune-mediated and infectious diseases. It includes a suite of proprietary assays to select pharmacologically potent strains, vast proprietary datasets from human interventional studies, and facilities for cGMP-compliant manufacturing of rationally defined bacterial consortia in powder form to help physicians have access to live bacteria drugs to treat autoimmune and inflammatory diseases easily.
Pendulum Systems is an AI company building the first intelligent supply chain planning platform. Pendulum AI predicts demand, optimizes supply, and puts assets on the map, all while continuously improving on its own. Our technology is the result of a decade of rigorous research and development and has been deployed across some of the most demanding environments on Earth. Today, Pendulum is at work for corporations and governments across six continents, driving margins and saving lives. In 2023, Macro-Eyes became Pendulum, shifting from an R&D focus to productization and commercial growth.

Lyell Immunopharma

Series A in 2018
Lyell is a T cell reprogramming company dedicated to the mastery of T cells to cure patients with solid tumors. Lyell focuses on addressing what it believes are the primary barriers that limit consistent, reliable and curative responses with adoptive T cell therapy: T cell exhaustion and loss of durable stemness, which includes proliferative capacity, ability to self-renew and ability to differentiate and eliminate solid tumors. Lyell is applying its proprietary ex vivo genetic and epigenetic reprogramming technology platforms, Gen-R and Epi-R, to address these barriers in order to develop new medicines with improved, durable, and potentially curative clinical outcomes.

Evolve Biosystems

Series C in 2018
Evolve Biosystems is a biotechnology company that specializes in providing microbiome-based products designed to develop, restore, and maintain. The company's platform focuses on solving the gut dysbiosis throughout the human life cycle as well as in various animal species, enabling physicians to maintain the healthy gut microbiome in newborn infants with a consumer-directed home use product, and a hospital-based neonatal ICU product.
Recursion is a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, data science, and engineering, with the goal of radically improving the lives of patients and industrializing drug discovery. Central to our mission is the Recursion Operating System, or Recursion OS, that combines an advanced infrastructure layer to generate what we believe is one of the world's largest and fastest-growing proprietary biological and chemical datasets and the Recursion Map, a suite of custom software, algorithms, and machine learning tools that we use to explore foundational biology unconstrained by human bias and navigate to new biological insights which may accelerate our programs. We are a biotechnology company scaling more like a technology company.

Scripps Research

Grant in 2018
Scripps Research is a leading not-for-profit organization dedicated to advancing biomedical research and education to enhance human health. Established in 1924, it originated from the Scripps Metabolic Clinic founded by philanthropist Ellen Browning Scripps. The institute is recognized globally for its significant contributions to health science, including the development of treatments for cancer, rheumatoid arthritis, and hemophilia. With approximately 3,000 employees across its campuses in La Jolla, California, and Jupiter, Florida, Scripps Research is home to renowned scientists, including three Nobel laureates, who are engaged in groundbreaking discoveries. Additionally, its graduate program in biology and chemistry is consistently ranked among the top ten in the United States, reflecting the institute's commitment to education and innovation in the biomedical sciences.

Novartis

Grant in 2018
Novartis is a Switzerland-based multinational healthcare company that focuses on developing innovative pharmaceuticals and healthcare solutions to meet the evolving needs of patients globally. Their product portfolio includes treatments in key therapeutic areas such as oncology, rare diseases, neuroscience, immunology, respiratory conditions, and cardio-metabolic diseases. The company is also a leader in animal health, creating medicines for pets, farm animals, and farmed fish to enhance their health and welfare. With a commitment to scientific research, Novartis employs a substantial workforce of scientists and engineers dedicated to advancing drug discovery through advanced technologies and high-throughput screening. They aim to address unmet medical needs, demonstrated by their extensive pipeline of new molecular entities targeting various diseases. Novartis operates globally, with the United States being a significant market, and emphasizes responsible practices within its business strategy to improve overall public health.

Manus Bio

Grant in 2018
Manus Bio Inc. recreates plant processes in microorganisms to produce natural ingredients through fermentation. The company’s microbial platform converts sugar sources into ingredients with applications, such as flavors, fragrances, food ingredients, cosmetics, vitamins, pharmaceuticals, and agricultural chemicals. It merges metabolic engineering, protein engineering, and systems biology technologies to generate microbes that produce various plant-based ingredients. The company has a strategic partnership with BBGI Public Company Limited. Manus Bio Inc. was formerly known as Manus Biosynthesis, Inc. and changed its name to Manus Bio Inc. in June 2018. The company was founded in 2011 and is based in Cambridge, Massachusetts. It has manufacturing facilities in Cambridge, Massachusetts; and Augusta, Georgia.
Pendulum Systems is an AI company building the first intelligent supply chain planning platform. Pendulum AI predicts demand, optimizes supply, and puts assets on the map, all while continuously improving on its own. Our technology is the result of a decade of rigorous research and development and has been deployed across some of the most demanding environments on Earth. Today, Pendulum is at work for corporations and governments across six continents, driving margins and saving lives. In 2023, Macro-Eyes became Pendulum, shifting from an R&D focus to productization and commercial growth.

IMMUNETHEP

Grant in 2017
Immunethep is a biotechnology company focused on drug development for Immune System related pathologies. Immunethep is a spin-off from the University of Porto that uses its proprietary technology to address unmet medical needs. Immunethep discovered a novel mechanism used by different pathogenic bacteria to suppress host immune response. By targeting this mechanism we are developing broad coverage anti-bacterial immunotherapies.

Ventria Bioscience

Grant in 2017
Ventria Bioscience is a privately held biopharmaceutical company with a product pipeline enabled by ExpressTec. ExpressTec is a patented, plant-based recombinant protein manufacturing technology that delivers a ten-fold higher recombinant protein yield than other plant-based systems. Ventria Bioscience's platform technology delivers meaningful and sustainable economic advantages by enabling new product opportunities that were not previously available. It can be used to develop new biotherapeutics, novel vaccines, reagents for biomanufacturing, and industrial and biofuel enzymes.

Visterra

Series C in 2017
Visterra, Inc. engages in pharmaceutical drug research and development of therapeutic and diagnostic products for infectious diseases. It also provides structure-based design of therapeutics and diagnostic platforms, based on an understanding of glycobiology and glycochemistry. The company was formerly known as Parasol Therapeutics, Inc. and changed its name in May 2010. Visterra, Inc. was founded in 2007 and is based in Cambridge, Massachusetts.

PnuVax

Grant in 2017
PnuVax Incorporated is dedicated to the production of high quality biopharmaceuticals for the promotion of public health worldwide. Their team has over 30 years of experience in the pharmaceutical industry, from research to full scale production.

Immunocore

Series B in 2017
Immunocore is focused on the discovery and development of novel T cell receptor-based drugs to treat diseases with a high unmet need, including cancer and viral disease. The company’s expertise in engineering T Cell Receptors (TCRs) and linking them to an antibody fragment (scFv) known as anti-CD3, has led to its first product candidate, IMCgp100, entering clinical trials in patients with metastatic melanoma. The proprietary T Cell Receptor technology platform is well validated and can easily be manufactured for clinical and commercial supply in microbial systems. Immunocore is a biotechnology company that specializes in the development of TCR bispecific immunotherapies.

Qloudlab

Grant in 2017
Qloudlab specializes in innovative healthcare solutions, particularly through its development of Sceptre, the world's first touchscreen-based biosensor. This modular platform facilitates a wide range of diagnostic tests, including blood, urine, saliva, and skin analyses, all within a single mobile system. By integrating smartphone technology with healthcare and cloud computing, Qloudlab aims to streamline diagnostics at the Point-of-Care, making testing more accessible and efficient. The company's technology is designed to be cost-effective, enhancing the user experience for both patients and healthcare professionals. Through its advancements, Qloudlab is positioned to transform the diagnostics landscape, ensuring that essential health information is readily available and easily obtainable.

Vaxess Technologies

Grant in 2017
Vaxess Technologies is developing the MIMIX™ sustained release patch technology, the easiest and most effective way to administer vaccines and therapeutics. For vaccines, the controlled release simulates the pace of a natural infection, helping the body produce a slow, strong, and enduring ramp-up of immune response, ultimately boosting a vaccine’s effectiveness. Engineered for stability, Vaxess’s patch does not require refrigeration and can be shipped to and applied in low resource settings.

AbCellera

Grant in 2017
AbCellera is an antibody discovery and development engine that’s specifically designed to address the barriers of conventional discovery, finding the optimal clinical candidate with greater precision and speed, getting to the clinic – and patients – sooner. With the integrated AbCellera platform, our experts search a wide range of diverse antibodies to select the most effective and developable leads fast and set our partners up for enduring success. We have extensive experience forging partnerships with emerging biotechs and leading pharmaceutical companies. AbCellera leverages proprietary hardware, software, tools along with the latest data science, to operate as strategic partners and help develop optimized solutions faster for any program.

Kymab

Grant in 2017
Kymab is a clinical-stage biopharmaceutical company developing fully human monoclonal antibody therapeutics with a focus on immune-mediated diseases and immuno-oncology using its proprietary, integrated platforms collectively called IntelliSelect®. Kymab’s IntelliSelect Transgenic platforms contain a full diversity of human antibodies, making them the most comprehensive antibody platforms available. The company was founded in 2010 and is based in Cambridge, the United Kingdom.

Vir

Venture Round in 2017
Vir Biotechnology is a commercial-stage immunology company developing therapeutic products to treat and prevent serious infectious diseases. The company brings together cutting-edge innovations with scientific expertise and management. It seeks to take a new approach, using breakthroughs in immune programming to manipulate pathogen-host interactions. Vir Biotechnology also focused on combining immunologic insights with cutting-edge technologies to treat and prevent serious infectious diseases. The company four current technology platforms are designed to, either individually or in combination, stimulate and enhance the immune system by exploiting critical observations of natural immune processes. Their vision is that one day, diseases like hepatitis B, influenza A, HIV, and tuberculosis become a thing of the past.

Univercells

Grant in 2016
Univercells is a One-stop-shop for high-density low-cost biomanufacturing "end-to-end" solutions, with innovative engineering able to decrease the needs for investments of over 75% and the cost of goods of up to 90%. Univercells' technologies, aimed at low cost manufacturing of antibodies/proteins/vaccines, is based on single-use technologies, and chaining of three manufacturing steps into simulated continuous mode : cell culture under perfusion, clarification and capture.

AgBiome

Grant in 2016
AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on developing innovative biological products for the agriculture industry. Founded in 2012, AgBiome utilizes advanced genomics and screening technologies to identify plant-associated microbes that enhance plant health, pest resistance, and crop yields. The company manufactures fungicides to protect crops from soil-borne and foliar diseases while also employing a platform that captures and screens diverse microbes for their effectiveness against insects, diseases, and nematodes. AgBiome collaborates with leading agricultural firms to accelerate its discovery process and deliver solutions that address critical challenges in global food production. With a workforce of approximately 87 employees and a state-of-the-art laboratory and greenhouse facility in the Research Triangle Park, AgBiome aims to provide sustainable and effective solutions for farmers facing significant agricultural issues.

Kymab

Series C in 2016
Kymab is a clinical-stage biopharmaceutical company developing fully human monoclonal antibody therapeutics with a focus on immune-mediated diseases and immuno-oncology using its proprietary, integrated platforms collectively called IntelliSelect®. Kymab’s IntelliSelect Transgenic platforms contain a full diversity of human antibodies, making them the most comprehensive antibody platforms available. The company was founded in 2010 and is based in Cambridge, the United Kingdom.

Masimo

Grant in 2016
Masimo Corporation, founded in 1989 and headquartered in Irvine, California, is a medical technology company that develops, manufactures, and markets innovative non-invasive patient monitoring measurements, sensors and devices, hospital automation and connectivity solutions, telehealth solutions, and consumer health and wellness devices. Masimo is best known for its pulse oximetry technology, Masimo Signal Extraction Technology® (SET®) — which today is considered to be modern pulse oximetry. Masimo SET® addresses the limitations of conventional pulse oximetry, such as its poor performance during patient motion or low perfusion. Founder and CEO Joe Kiani was inspired to develop more reliable, accurate technology after observing ineffective pulse oximetry in the neonatal care unit (NICU). Masimo’s pulse oximetry is at the heart of many of its monitoring devices and products. In 2023, SET®’s origin — as a way to more reliably monitor NICU babies — came full circle with the introduction of Masimo Stork™, a baby monitor that uses SET® and other advanced technologies to help parents track their babies’ health indicators at home. In addition to Masimo SET®, the company has developed numerous noninvasive measurements (collectively known as the rainbow SET® family of measurements), a suite of advanced devices like the Root® patient monitoring and connectivity platform, many other innovative bedside, handheld, and tetherless devices, and remote patient monitoring and management solutions like Masimo Patient SafetyNet™ and Masimo SafetyNet These devices and solutions help caregivers monitor numerous physiological parameters including blood oxygen saturation (SET® SpO2), total hemoglobin (SpHb®) carboxyhemoglobin (SpCO®), fluid responsiveness (PVi®), methemoglobin (SpMet), respiration rate from the pleth (RRp®), brain function while sedated (SedLine®), regional and cerebral oximetry (O3®), cardiac output (LiDCO™), end-tidal carbon dioxide and other capnography measurements (NomoLine®), acoustic respiratory rate (RRa®), and more. Masimo also develops therapeutic products like Masimo softFlow™ which delivers respiratory support to patients with spontaneous breathing. Additionally, Bridge™ by Masimo is a non-drug device that alleviates symptoms of opioid withdrawal through neuromodulation — making recovery safer and easier. Masimo also offers the first FDA-authorized device to alert users in the event of an opioid overdose, Opioid Halo™, and wearable devices like the Masimo W1™ advanced health tracking watch. The company sells its products to end-users through direct sales and distributors, as well as to original equipment manufacturers (OEMs) and other partners to incorporate into their products.

Batavia Biosciences

Grant in 2016
Batavia Biosciences focuses on accelerating the transition of biopharmaceutical product candidates from discovery to the clinic with improved success and lower cost. Our services cover candidate selection, production of research materials, upstream and downstream process development, assay development, product characterization and clinical manufacturing and release. Batavia Biosciences has successfully worked on viral and bacterial vaccines, recombinant proteins, antibodies and gene therapy products. Unique technologies such as STEP® protein expression technology and SCOUT® high throughput process technology accelerate timelines and reduce costs.

Just - Evotec Biologics

Series A in 2016
Just Evotec Biologics was founded in 2014 and acquired by Evotec in 2019. The company has an intense focus on the design of innovative and integrated technologies to accelerate the development of biotherapeutics and reduce their manufacturing cost. Core strengths include antibody discovery, molecular design, process and product design and manufacturing plant design.
Hangzhou Just Biotherapeutics is a comprehensive high-tech design company dedicated to accelerating the development of bio-medicine and significantly reducing manufacturing costs. Their core strengths are molecular design, process design, drug product design and manufacturing plant design.

Takeda

Grant in 2016
Takeda Pharmaceutical Company Limited, founded in 1781 and based in Tokyo, Japan, is a leading research-based pharmaceutical firm. It operates primarily in the pharmaceutical sector, focusing on five core therapeutic areas: oncology, gastroenterology, neuroscience, rare diseases, and plasma-derived therapies, which collectively contribute to over 80% of its revenue. The company markets a range of original products, including treatments for cancer, ulcers, hypertension, and diabetes. Takeda's venture capital arm, Takeda Ventures, Inc., specializes in direct and fund of fund investments, primarily targeting therapeutic innovations in cardiometabolic disorders, central nervous system diseases, chronic inflammatory conditions, and oncology. The firm invests globally, with a preference for the United States, Canada, and Europe, aiming to support early-stage companies and foster collaborations that leverage Takeda's extensive research and development capabilities. With a diversified revenue stream—50% from the US, 20% from Japan, and 20% from Europe and Canada—Takeda continues its transformation into an agile global leader in pharmaceuticals.

Moderna

Grant in 2016
Moderna Therapeutics is a biotechnology company that develops messenger RNA therapeutics. Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. It provides in vivo drug modality that produces human proteins or antibodies inside patient cells. Moderna Therapeutics also develops various patent applications with various claims ranging from novel nucleotide chemistries to specific drug compositions. It focuses on disease areas, such as inherited genetic disorders, hemophilia, and blood factors, and oncology. Moderna Therapeutics in 2010 and is headquartered in Cambridge in Massachusetts. It has strategic option agreements with AstraZeneca and Alexion Pharmaceuticals and strategic collaborations with Karolinska Institutet, Institut Pasteur, Karolinska University Hospital, and Merck.

Atreca

Series A in 2015
Atreca is a biopharmaceutical that develops a technology to identify the set of antibodies produced during an immune response, without prior knowledge of an antigen. Its product candidate, ATRC-101, is a monoclonal antibody in preclinical development with a novel mechanism of action and target-derived from an antibody identified using its discovery platform.

AgBiome

Series B in 2015
AgBiome, LLC is a biotechnology company based in Durham, North Carolina, that focuses on developing innovative biological products for the agriculture industry. Founded in 2012, AgBiome utilizes advanced genomics and screening technologies to identify plant-associated microbes that enhance plant health, pest resistance, and crop yields. The company manufactures fungicides to protect crops from soil-borne and foliar diseases while also employing a platform that captures and screens diverse microbes for their effectiveness against insects, diseases, and nematodes. AgBiome collaborates with leading agricultural firms to accelerate its discovery process and deliver solutions that address critical challenges in global food production. With a workforce of approximately 87 employees and a state-of-the-art laboratory and greenhouse facility in the Research Triangle Park, AgBiome aims to provide sustainable and effective solutions for farmers facing significant agricultural issues.

Ceres Nanosciences

Grant in 2015
Ceres Nanosciences Inc. (“Ceres”) is a privately held life sciences company engaged in the research, development, and commercialization of innovative sample preparation products, based on its proprietary Nanotrap® technology, which captures, enriches and preserves analytes/biomarkers. Early detection of biomarkers, in particular those of low abundance, is key to the diagnosis and treatment of diseases such as cancer, cardiac, and infectious diseases, resulting in improved patient benefit and reduced health care costs. Ceres has a broad product pipeline of advanced sample collection technologies and diagnostics, funded through federal agency grants and industry collaboration funding. Ceres’ lead product in development is a direct antigen test for the diagnosis of Lyme disease, which will be available commercially in 2015.

Schrödinger

Series D in 2015
Schrödinger develops a computational platform that facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger also has wholly-owned and collaborative drug discovery programs in a broad range of therapeutic areas. Schrödinger is deeply committed to investing in the science and talent that drive its computational platform.
Hangzhou Just Biotherapeutics is a comprehensive high-tech design company dedicated to accelerating the development of bio-medicine and significantly reducing manufacturing costs. Their core strengths are molecular design, process design, drug product design and manufacturing plant design.

Synlogic

Series A in 2014
Synlogic is a biotechnology company that develops synthetic biotic medicines to perform metabolic functions to treat diseases. The company's lead programs target patients with rare genetic metabolic diseases, including phenylketonuria and secondary hyperoxaluria. Synlogic is also hard at work on synthetic biotics to address more prevalent conditions, including inflammatory bowel disease, cancer, and other metabolic conditions.

Genocea Biosciences

Grant in 2014
Genocea Biosciences is a biopharmaceutical company which is engaged in developing novel vaccines and immunotherapies to address diseases with significant unmet needs.Its product candidate includes GEN-003 which is an immunotherapy for the treatment of genital herpes as well as it owns pre-clinical immuno-oncology program focused on personalized cancer vaccines. The company focuses on developing vaccines and immunotherapies for unmet needs through its AnTigen Lead Acquisition System, which is used to design vaccines and immunotherapies. Genocea operates its business through the single segment being Developing and Commercializing vaccines.
Oregon Health & Science University is dedicated to improving the health and quality of life for all Oregonians through excellence, innovation and leadership in health care, education and research. OHSU is the kind of place where the big news doesn't always involve sports, politics, fashion or even weather. The big news is always about health — health care, health education, health-related research. And various organizations and publications that rank American institutions, programs and faculty in a variety of categories have taken note. Nearly one million patient visits each year. Educating thousands of future health care providers. You get the picture. Immerse yourself in more facts and stats than you probably need about Portland's largest employer, Oregon's provider of care to every corner of the state, and one of the nation's top 28 biomedical research institutions. Oregon Health & Science University is the state’s only academic health center. It provides an uncommon array of services from providing the state’s most comprehensive health care, to educating the next generation of clinicians and biomedical researchers, to achieving breakthroughs and innovations.

SomaLogic

Grant in 2014
SomaLogic operates as a protein biomarker discovery and clinical diagnostics company. It offers SOMAmers (Slow-Offrate Modified Aptamers), which are modified nucleic acid-based protein-binding reagents that are specific for their cognate protein; and SOMAscan that provides protein detection and equipment. The company’s SOMAmer/SOMAscan technology enables to discover protein biomarker signatures; drug discovery and development; and clinical diagnostics. Its products have applications in the diagnostics of various diseases in oncology, neurology, cardiovascular and metabolic disease, and other diseases and conditions. SomaLogic was founded in 1999 and is headquartered in Boulder, Colorado.

Kymab

Series B in 2014
Kymab is a clinical-stage biopharmaceutical company developing fully human monoclonal antibody therapeutics with a focus on immune-mediated diseases and immuno-oncology using its proprietary, integrated platforms collectively called IntelliSelect®. Kymab’s IntelliSelect Transgenic platforms contain a full diversity of human antibodies, making them the most comprehensive antibody platforms available. The company was founded in 2010 and is based in Cambridge, the United Kingdom.

Visterra

Series A in 2013
Visterra, Inc. engages in pharmaceutical drug research and development of therapeutic and diagnostic products for infectious diseases. It also provides structure-based design of therapeutics and diagnostic platforms, based on an understanding of glycobiology and glycochemistry. The company was formerly known as Parasol Therapeutics, Inc. and changed its name in May 2010. Visterra, Inc. was founded in 2007 and is based in Cambridge, Massachusetts.

ZYOMYX

Series B in 2013
Zyomyx has a unique expertise in and passion for tackling difficult “outside-the-box” problems. Highly user-friendly, instrument-free point-of-care tests need to be designed with an advanced level of cartridge engineering and reagent stability, and aligned with aggressive cost targets. Zyomyx specializes in exactly these demanding product requirements. Our immediate focus is an advanced, but simple to use and inexpensive CD4 T-cell point-of-care test that will be launched globally and configured to especially meet the demanding specifications for use in low and middle income countries.

Tetragenetics

Grant in 2013
Tetragenetics is an early-stage biotechnology company meeting the needs of customers who seek a cost-effective alternative platform technology for the production of genetically engineered proteins. Their technology is particularly well suited to the production of eucaryotic membrane and secretory proteins that are difficult to express in conventional systems. Such proteins include vaccine antigens, monoclonal antibodies, and a variety of therapeutic proteins for the treatment and prevention of human and animal disease.

Visterra

Series A in 2012
Visterra, Inc. engages in pharmaceutical drug research and development of therapeutic and diagnostic products for infectious diseases. It also provides structure-based design of therapeutics and diagnostic platforms, based on an understanding of glycobiology and glycochemistry. The company was formerly known as Parasol Therapeutics, Inc. and changed its name in May 2010. Visterra, Inc. was founded in 2007 and is based in Cambridge, Massachusetts.

Genocea Biosciences

Series C in 2012
Genocea Biosciences is a biopharmaceutical company which is engaged in developing novel vaccines and immunotherapies to address diseases with significant unmet needs.Its product candidate includes GEN-003 which is an immunotherapy for the treatment of genital herpes as well as it owns pre-clinical immuno-oncology program focused on personalized cancer vaccines. The company focuses on developing vaccines and immunotherapies for unmet needs through its AnTigen Lead Acquisition System, which is used to design vaccines and immunotherapies. Genocea operates its business through the single segment being Developing and Commercializing vaccines.

Atreca

Venture Round in 2012
Atreca is a biopharmaceutical that develops a technology to identify the set of antibodies produced during an immune response, without prior knowledge of an antigen. Its product candidate, ATRC-101, is a monoclonal antibody in preclinical development with a novel mechanism of action and target-derived from an antibody identified using its discovery platform.

YourBio Health

Grant in 2011
YourBio Health is developing novel products to optimize the interface of diagnostic medicine and the healthcare consumer by dramatically simplifying blood sampling and testing. By eliminating the barriers to the acquisition of critical diagnostic information, Seventh Sense is contributing to the future of informed, effective healthcare delivery and patient participation in their own well-being. The Seventh Sense On Vivo™ platform will enable diagnostic testing to be performed safely and painlessly by virtually anyone, anywhere. Their proprietary, single-step Touch Activated Phlebotomy™ (TAP™) technology can be combined with a variety of diagnostic assays for rapid results. TAP's revolutionary sampling capabilities may also integrate with analytical systems to vastly improve the patient and clinician experience.

Liquidia Technologies

Venture Round in 2011
Liquidia Technologies is a late-stage clinical biopharmaceutical company based in Morrisville, North Carolina, that specializes in the development and commercialization of human therapeutics. The company utilizes its proprietary PRINT technology, a particle engineering platform that allows for the precise production of uniform drug particles, aimed at improving the safety, efficacy, and performance of various therapies. Liquidia is currently advancing two key product candidates: LIQ861 for the treatment of pulmonary arterial hypertension and LIQ865 for addressing local post-operative pain. In addition to its internal pipeline, Liquidia collaborates with leading pharmaceutical companies to leverage its PRINT technology across multiple therapeutic areas and drug types. The company also offers strategy and commercialization services for rare disease pharmaceutical products, including a generic formulation of treprostinil for pulmonary arterial hypertension. Founded in 2004, Liquidia Technologies continues to focus on transforming patient care through innovative therapeutic solutions.

BlueWillow Biologics

Grant in 2010
BlueWillow Biologics operates as a clinical-stage, privately-held biopharmaceutical company. It focuses on developing and commercializing topical antiseptic and anti-infective products and intranasal vaccines using its patented nanotechnology platform. Its platform employs novel oil-in-water nano-droplets for products administered to the skin and nose. The company was founded as a spin-off from the University of Michigan and is headquartered in Ann Arbor, Michigan.

Tetragenetics

Grant in 2009
Tetragenetics is an early-stage biotechnology company meeting the needs of customers who seek a cost-effective alternative platform technology for the production of genetically engineered proteins. Their technology is particularly well suited to the production of eucaryotic membrane and secretory proteins that are difficult to express in conventional systems. Such proteins include vaccine antigens, monoclonal antibodies, and a variety of therapeutic proteins for the treatment and prevention of human and animal disease.
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