Higin Capital

KAICO, Ltd. is a biotechnology company based in Fukuoka, Japan, established in 2018. It specializes in the manufacture of hard-to-express proteins utilizing a unique silkworm-baculovirus expression system. This innovative approach allows KAICO to produce high-quality proteins that are crucial for the development of various healthcare applications, including drugs, vaccines, diagnostic agents, and reagents. The company's focus on protein design and processing technology enables drug researchers to create new treatments and advancements in regenerative medicine. Through its expertise, KAICO plays an essential role in supporting the pharmaceutical industry by offering contract expression reagents and pharmaceutical raw materials.

AMI Co., Ltd is a Japanese company based in Minamata-shi, established in 2015, that specializes in the manufacturing of medical equipment, primarily stethoscopes. In addition to producing medical devices, AMI is involved in healthcare consulting, offering services such as hospital management and clinical research. The company is also focused on developing telehealth solutions, including a telemedicine system that enhances remote medical consultations. Among its innovations is a video chat platform designed for remote auscultation, which allows for the separate transmission of heart sounds as both audible and visible data, thereby improving patient access to medical services through telemedicine initiatives.

F.MED is a manufacturing company that designs and develops robotic microsurgical devices for the healthcare industry.

Revorn Co., Ltd., based in Tokyo, Japan, specializes in manufacturing and providing odor sensing solutions. The company leverages its proprietary 'iinioi AI' technology to collect and analyze scent data globally. Revorn's product portfolio includes a range of odor sensors and related software, such as investor software, revorn instance management, insense, kaorino tabibit, omoi deno kaori, and attention bias modification trainer. Additionally, Revorn offers consultation services that address various levels of odor-related issues, from identification to solution development.

Manpuku Holdings operates a diverse food service business in Japan, managing multiple restaurant brands that specialize in sushi, yakiniku, fried chicken, bento, and rice balls. The company aims to invigorate Japan's culinary scene by offering a range of dining experiences, thereby enriching the country's gastronomic culture.

ByWill specializes in brand consulting and green transformation services, aiming to foster sustainability and enhance corporate value. Its offerings include market research, execution support, organizational strengthening consulting, cultural surveys, and environmental value creation assistance, empowering clients to strive towards carbon neutrality.

StapleBio is a biotechnology company focused on the research and development of pharmaceuticals utilizing advanced staple nucleic acid technology. The company has developed a unique platform that selectively hybridizes with target messenger ribonucleic acid (mRNA) to create an artificial ribonucleic acid higher-order structure, known as RNA G-quadruplex (RGq). This innovative approach allows for the modulation of protein expression levels without relying on enzymatic bioprocesses commonly used in RNA interference or antisense technologies. By enabling the introduction of artificial nucleic acids into various sequences, StapleBio's technology has significant potential applications in detecting and treating conditions such as cancer, neurological disorders, autoimmune diseases, and viral infections.

Liberaware specializes in developing non-GPS small drones tailored for industrial use, with a focus on indoor confined-space inspections. The company offers IoT and AI-driven solutions to enhance the capabilities of these drones. Additionally, Liberaware provides inspection services, drone rentals and sales, as well as data processing and analysis services for the information collected by their equipment.

Restore Vision is a biotechnology company focused on developing innovative therapies for eye diseases, particularly retinitis pigmentosa. The company specializes in gene therapy that employs advanced chimeric rhodopsin genes, which enhance the functionality of conventional rhodopsins. This technology aims to address the limitations of traditional treatments, providing high sensitivity and improved outcomes for patients suffering from intractable eye conditions. Through its research and development efforts, Restore Vision seeks to create effective therapeutic agents that significantly contribute to the field of ocular health.

Vivid Garden Inc. is an agriculture company based in Minato, Japan, founded in 2016. It operates as an online marketplace that connects producers with consumers and restaurants, enabling direct sales of farm products, ingredients, and flowers. The company manages several platforms, including Tabe Choku, which facilitates consumer-to-consumer sales of agricultural products, and Tabe Choku Pro, a specialized service for restaurants to order ingredients. Additionally, Vivid Garden offers Eat Chok, a platform designed to support farmers in delivering their products to office locations. Through these initiatives, Vivid Garden aims to streamline the distribution of fresh produce while enhancing access for both consumers and businesses.

KitchHike, Inc. is an online platform that facilitates connections between cooks and travelers seeking authentic culinary experiences. Founded in 2012 and headquartered in Tokyo, Japan, the company enables users to enjoy home-cooked meals prepared by local chefs, cooks, and homemakers. By inviting travelers into their kitchens, these hosts offer a chance to savor traditional dishes while fostering a sense of community and cultural exchange. KitchHike's service allows users to experience local cuisine in a personal and intimate setting, enhancing their travel experience through shared meals and interactions with local residents.

Timee, established in 2017 and headquartered in Shibuya-ku, Japan, specializes in developing and operating applications. Its flagship product is a work sharing platform that connects available workers with businesses facing labor shortages, addressing the issue of fluctuating work demands. As Japan's leading gig work platform, Timee aims to expand work opportunities and alleviate labor market imbalances.

AMI Co., Ltd is a Japanese company based in Minamata-shi, established in 2015, that specializes in the manufacturing of medical equipment, primarily stethoscopes. In addition to producing medical devices, AMI is involved in healthcare consulting, offering services such as hospital management and clinical research. The company is also focused on developing telehealth solutions, including a telemedicine system that enhances remote medical consultations. Among its innovations is a video chat platform designed for remote auscultation, which allows for the separate transmission of heart sounds as both audible and visible data, thereby improving patient access to medical services through telemedicine initiatives.

Kokopelli Inc. is a technology solutions provider based in Tokyo, Japan, focused on serving small and medium-sized enterprises. Founded in 2007, the company develops and offers the management support platform "Big Advance," along with the AI module "FAI," which enhances credit assessments for financial institutions. In addition to these core products, Kokopelli provides a range of services that include management support, task management, productivity tools, bookkeeping, payroll accounting, and web production assistance. Through its innovative solutions, Kokopelli aims to streamline operations and improve efficiency for its clients in Japan's competitive business landscape.

AMI Co., Ltd is a Japanese company based in Minamata-shi, established in 2015, that specializes in the manufacturing of medical equipment, primarily stethoscopes. In addition to producing medical devices, AMI is involved in healthcare consulting, offering services such as hospital management and clinical research. The company is also focused on developing telehealth solutions, including a telemedicine system that enhances remote medical consultations. Among its innovations is a video chat platform designed for remote auscultation, which allows for the separate transmission of heart sounds as both audible and visible data, thereby improving patient access to medical services through telemedicine initiatives.