BioBrit

Creyon Bio is a pre-clinical stage company focused on advancing drug development through a data-driven methodology. It specializes in engineering RNA-based medicines and their components by creating proprietary datasets that inform advanced machine learning models. This innovative approach enables the rapid identification of design rules and engineering principles necessary for the development of safe and effective oligonucleotide-based medicines. By leveraging these insights, Creyon Bio aims to improve the efficiency of the drug development process, ultimately contributing to cost savings in the healthcare sector while catering to diverse patient populations.

Basilard BioTech specializes in a proprietary platform that revolutionizes the burgeoning cell-based therapies market. Its technology enables efficient gene delivery through a mechanical approach, enhancing cell viability and transfection performance.

Amplo Biotechnology is a biotechnology company developing adeno-associated viral therapies aimed at curing defects in neuromuscular junctions, with an initial focus on congenital myasthenic syndromes. Its lead program, AAV-Dok7, originated with a research team from the Institute of Medical Science at the University of Tokyo and is designed to be delivered via intravascular injection to trigger molecular events that address paralysis, breathing, and swallowing difficulties caused by neuromuscular junction defects.

Stuart Therapeutics is a biotechnology company focused on developing innovative therapies for ophthalmic conditions. The company's primary offering, PolyCol, is a synthesized peptide therapeutic platform designed to repair disease-damaged helical collagen in the eye. This platform facilitates accelerated healing of epithelial cells, restoration of nerve function, and reduction of inflammation, making it a promising treatment for various ophthalmic diseases, including dry eye disease, dry age-related macular degeneration, and glaucoma. PolyCol is based on patented research from a major U.S. university, supplemented by additional intellectual property acquired by the company. Beyond ophthalmic applications, Stuart Therapeutics is also exploring PolyCol's potential in treating gastrointestinal, inflammatory, and oncology conditions.

Primmune Therapeutics is a biotechnology company developing orally administered small molecule toll-like receptor 7 (TLR7) agonists to stimulate innate immunity in cancer immunotherapy. The TLR7 agonists aim to activate systemic innate immune responses, promoting cytokine and chemokine production, NK cell activation, and B-cell proliferation to support anti-tumor activity. The company intends to combine these agents with adaptive cancer therapies such as checkpoint inhibitors to improve response rates and durability, and targets metastatic cancers.

Primmune Therapeutics is a biotechnology company developing orally administered small molecule toll-like receptor 7 (TLR7) agonists to stimulate innate immunity in cancer immunotherapy. The TLR7 agonists aim to activate systemic innate immune responses, promoting cytokine and chemokine production, NK cell activation, and B-cell proliferation to support anti-tumor activity. The company intends to combine these agents with adaptive cancer therapies such as checkpoint inhibitors to improve response rates and durability, and targets metastatic cancers.

Castle Biosciences is a molecular diagnostics company headquartered in Friendswood, Texas, that develops and commercializes gene‑expression‑profile tests for dermatologic cancers, uveal melanoma, and Barrett’s esophagus. Its flagship product, DecisionDx‑Melanoma, predicts the risk of metastasis in stage I and II cutaneous melanoma by analyzing 31 tumor‑derived genes. The company also offers DecisionDx‑UM for uveal melanoma, DecisionDx‑SCC for cutaneous squamous cell carcinoma, MyPath Melanoma for diagnostically challenging melanocytic lesions, and TissueCypher for predicting progression of high‑grade dysplasia in Barrett’s esophagus. Tests are delivered to physicians, physician assistants, and nurse practitioners to support personalized treatment decisions. Founded in 2007, Castle Biosciences focuses on providing clinically actionable genomic information to improve cancer diagnosis and management.

SiteOne Therapeutics is a San Francisco-based company developing innovative therapeutics and diagnostics for acute and chronic pain. Their lead candidates are selective inhibitors of the Naᵥ1.7 ion channel, aiming to treat pain safely and effectively without relying on NSAIDs or opioids.

SiteOne Therapeutics is a San Francisco-based company developing innovative therapeutics and diagnostics for acute and chronic pain. Their lead candidates are selective inhibitors of the Naᵥ1.7 ion channel, aiming to treat pain safely and effectively without relying on NSAIDs or opioids.

SiteOne Therapeutics is a San Francisco-based company developing innovative therapeutics and diagnostics for acute and chronic pain. Their lead candidates are selective inhibitors of the Naᵥ1.7 ion channel, aiming to treat pain safely and effectively without relying on NSAIDs or opioids.