CLI Ventures

Sentieon, Inc. is a biotechnology company founded in 2014 and headquartered in Mountain View, California, specializing in cloud-based bioinformatics solutions for the life sciences and clinical markets. The company develops a suite of bioinformatics tools designed for the efficient processing of genomics data, focusing on high accuracy and computational efficiency. Key products include Sentieon DNAseq, which facilitates germline DNA analysis, and Sentieon TNseq, used for detecting somatic variants in tumor-normal samples. Sentieon's software solutions are characterized by their scalability, deployability, and upgradability, allowing them to adapt to various user needs. The company's advanced algorithms and robust software implementation ensure rapid turnaround times and consistent results, benefiting scientists, clinicians, and patients by enhancing precision in genomic data analysis.

Synlogic, Inc. is a clinical-stage biopharmaceutical company based in Cambridge, Massachusetts, specializing in the development of synthetic biotic medicines aimed at treating metabolic, inflammatory, and cancer-related diseases. The company’s lead therapeutic program, SYNB1618, is currently undergoing Phase I/IIa clinical trials for the treatment of phenylketonuria, a rare genetic metabolic disorder. Additionally, Synlogic is advancing SYNB1891, an intratumoral synthetic biotic medicine in Phase I clinical trials targeting solid tumors and lymphoma. The company employs a proprietary approach that utilizes engineered probiotics, specifically Escherichia coli Nissle 1917, to create GI-restricted oral therapies that are non-colonizing and reversible, facilitating easier administration and storage. Synlogic is also exploring treatments for other conditions, including secondary hyperoxaluria, inflammatory bowel disease, and various metabolic disorders, and has established a collaboration with Ginkgo Bioworks to further its development efforts.

Immune-Onc Therapeutics, Inc. is a clinical-stage biopharmaceutical company based in Palo Alto, California, founded in 2016. The company specializes in the discovery and development of innovative biologic therapies aimed at treating cancer. Immune-Onc Therapeutics focuses on the tumor microenvironment and immune suppressive pathways, utilizing advanced scientific insights to create novel immuno-oncology products. The company employs a targeted approach to develop first-in-class therapeutic antibodies that disarm immune suppression in tumors, thereby enhancing the immune response against cancer. Through its differentiated pipeline, Immune-Onc Therapeutics aims to provide new treatment options for cancer patients, addressing critical needs in the field of immunology and oncology.

Eonite Perception Inc. specializes in developing advanced inside-out positional tracking software that enhances machines' ability to perceive and interact with the real world. Founded in 2015 and based in Palo Alto, California, the company provides a three-dimensional mapping and ego-tracking system utilizing commodity dense depth sensors. Eonite's technology serves various applications, including augmented and virtual reality, home-scale 3D scanning, and industries such as robotics, architecture, engineering, and construction. Their software development kit empowers developers to create applications that require high positional accuracy and low latency, facilitating innovations in robotics and drones. By leveraging proprietary computer vision algorithms, Eonite aims to redefine how devices localize and detect obstacles, contributing to the future of immersive technologies and intelligent machines.

Medigo, headquartered in Berlin, operates a digital platform that facilitates medical travel. It connects users with clinics worldwide, enabling them to search, compare, and coordinate medical procedures. The platform offers features like clinic browsing by procedure or country, filtering by facility type, sorting by price or rating, and clinic comparison based on staff expertise and patient reviews. Medigo also acts as a third-party administrator, supporting organizations in global healthcare navigation, cost containment, and member experience enhancement. It maintains an international provider network and is backed by prominent venture capital firms, employing a diverse team of over 50 individuals.

Aria Pharmaceuticals is a preclinical-stage pharmaceutical company focused on discovering and developing innovative small molecule therapies for complex and difficult-to-treat diseases. Utilizing an artificial intelligence-driven drug discovery platform, Aria aims to identify promising drug candidates and streamline the drug development process. The company emphasizes a redefined approach to drug discovery that significantly reduces the time required for development and increases success rates compared to traditional methods. With a diverse range of therapeutic areas in its pipeline, Aria addresses over 1,000 diseases and collaborates with biotechnology and pharmaceutical partners to enhance the discovery and development of novel drug candidates. Founded in 2014 and based in Mountain View, California, Aria Pharmaceuticals is committed to providing breakthrough treatments for patients in need.

Civil Maps is a geospatial technology company based in Berkeley, California, specializing in artificial intelligence-based mapping solutions. The company offers a sensor-agnostic platform that enables high-accuracy, low-cost 3D HD mapping and localization, catering to various industries including transportation, telecommunications, and energy. Civil Maps' technology is utilized by automotive original equipment manufacturers (OEMs), mapping companies, and mobility providers to enhance their autonomous driving capabilities. By integrating their localization technology with diverse sensor configurations, Civil Maps allows vehicles to develop a comprehensive understanding of their environment through its proprietary Fingerprint Basemap Technology. This innovative approach significantly reduces the costs and energy requirements for large-scale deployment of autonomous vehicles and delivery systems while ensuring safe and efficient navigation on all road types.

Flirtey Technology Pty Ltd specializes in drone delivery services, focusing on urgent medical supplies, retail items, and food delivery across the United States. Founded in 2013 and headquartered in Reno, Nevada, the company aims to enhance lifestyles by providing instant delivery solutions. Flirtey has achieved significant milestones in the drone delivery industry, being the first to conduct an FAA-approved drone delivery, the first to perform a fully autonomous delivery to a home, and the first to launch a commercial drone delivery service.

Genalyte, Inc. is a clinical and diagnostic life sciences company based in San Diego, California, that specializes in rapid diagnostic testing solutions for healthcare providers, patients, and researchers. Founded in 2007, Genalyte has developed a unique technology platform employing silicon photonic biosensors to quantify the interactions between biomolecules, such as antibodies and proteins. This innovative approach allows for the direct measurement of protein binding and nucleic acid hybridization, facilitating the monitoring of autoimmune diseases, cancer biomarker screening, and the detection of infectious agents, including Ebola. The company's Maverick platform enables rapid testing in various healthcare settings, with results typically available in under thirty minutes, thereby enhancing patient care and improving resource efficiency within the healthcare system.

Industrial Microbes designs and builds microbes that produce better chemicals with lower costs and lower carbon emissions. We use greenhouse gases as the raw materials, including biogas, natural gas, and carbon dioxide. We scale our process with global chemical producers.

CoPromote, Inc. operates a social exchange platform designed to assist content creators in expanding their audiences. The platform allows users to promote their content within a community, connect with other creators who can share their promotions, and discover content to share with their own networks. It facilitates real-time engagement with the fans of other influencers, encouraging the exchange of content through promotions. CoPromote serves a diverse range of users, including artists, bloggers, brands, businesses, musicians, and websites. Originally founded in 2009 as Headliner.fm Corp., the company rebranded to CoPromote, Inc. in February 2014 and is headquartered in New York, New York.

Propel(x), Inc. is an online investment platform that connects investors with early-stage companies in the life sciences, computer sciences, energy, clean technology, and materials sectors. Founded in 2014 and based in Palo Alto, California, Propel(x) focuses on facilitating investments in startups centered around scientific discovery and innovative technologies. The platform enables investors to interact with industry experts, startup executives, and customers, which helps clarify complex technologies and accelerates fundraising efforts for emerging companies. Propel(x) aims to support the growth of pioneering ventures that contribute to significant advancements in various fields.

InsideMaps Inc. is a technology company based in Mountain View, California, that specializes in creating photorealistic 3D models and floor plans of home interiors. Founded in 2013, InsideMaps offers a user-friendly app for smartphones and tablets, allowing users to generate immersive, web-based 3D environments of their homes. This platform enables potential home buyers to visualize interiors and assists homeowners in experimenting with furniture arrangements and home improvements, such as changing paint or flooring. By providing high-definition photography and detailed floor plans, InsideMaps facilitates virtual interior design, allowing users to customize furniture selections and finishes, thereby enhancing the home buying and improvement experience.

Aria Pharmaceuticals is a preclinical-stage pharmaceutical company focused on discovering and developing innovative small molecule therapies for complex and difficult-to-treat diseases. Utilizing an artificial intelligence-driven drug discovery platform, Aria aims to identify promising drug candidates and streamline the drug development process. The company emphasizes a redefined approach to drug discovery that significantly reduces the time required for development and increases success rates compared to traditional methods. With a diverse range of therapeutic areas in its pipeline, Aria addresses over 1,000 diseases and collaborates with biotechnology and pharmaceutical partners to enhance the discovery and development of novel drug candidates. Founded in 2014 and based in Mountain View, California, Aria Pharmaceuticals is committed to providing breakthrough treatments for patients in need.

HireTeamMate is an employment agency developing a recommended tool throughout the recruiting community.

Voxel is a company that specializes in a virtualization platform designed to enhance mobile application development. Founded in 2013 and based in Palo Alto, California, Voxel enables users to build applications that run in the cloud, streaming seamlessly to client devices. The company also focuses on transforming mobile advertising by allowing users to engage with apps before making a purchase decision. This "try before they buy" approach enhances the app discovery process, ensuring that each visit to the app store is intentional and contributes to a higher lifetime value for users.

Publet, Inc. is a content marketing software company based in San Francisco, California. The firm specializes in amplifying B2B white papers and collateral through social and mobile platforms to generate sales leads. Its software transforms static PDF reports into engaging multimedia content by extracting quotes and text snippets that can be easily shared on social media. When potential leads interact with these posts, Publet tracks their engagement and directs them to a traditional paywall and contact form upon clicking the link. This approach enhances the visibility and accessibility of professional publications while facilitating lead generation for organizations.

CStorePro Inc. is a software company based in Sugar Land, Texas, that specializes in providing online store management and back-office solutions for convenience store and gas station owners in the United States. Founded in 2013, the company offers a user-friendly software-as-a-service (SaaS) platform that enables operators to monitor sales, manage inventory, and generate daily reports directly from their smartphones or tablets. Its solutions facilitate the management of various operational tasks, including pricing adjustments, merchandise sales, and financial transactions, while ensuring compliance with regulatory standards. By integrating operational and sales data, CStorePro helps retailers optimize their pricing, purchasing, and human resources, making it an essential tool for thousands of store owners and operators seeking to streamline their retail operations.

Droplet Inc. specializes in developing a robotic water sprinkler system designed to optimize plant irrigation. By utilizing data from weather stations, soil samples, and biological plant information, the system intelligently decides when, where, and how much water to deliver. This innovative solution caters to a variety of plant types, including grass, trees, and potted plants, and is applicable for use in gardens and lawns by homeowners. Founded in 2013 and based in the United States, Droplet Inc. aims to enhance irrigation efficiency while conserving water, leveraging advancements in robotics and cloud computing to transform traditional sprinkler systems.

Arthena is a venture-backed financial technology company that specializes in art investment through a quantitative investment platform. By utilizing data science, Arthena provides investors access to the fine arts market, allowing them to invest in art as an asset class. The company enables investors to pool their capital to form small collections of fine art, referred to as syndicates, which cater to different risk tolerances. Arthena is dedicated to enhancing transparency in art investing, offering investors insights into acquired assets and artists, thus fostering informed investment decisions.

popSLATE Media, Inc., based in San Francisco, California, specializes in a smart digital case for smartphones. This case features an ePaper screen on the back, allowing users to display images from their gallery, camera, social media, or popSLATE's artist channels, providing an always-on, low-power display for personal content.

Weft, Inc. is a global logistics data company based in Cambridge, Massachusetts, that specializes in providing real-time asset intelligence to enhance supply chain operations. Established in 2013 and operating as a subsidiary of Genscape, Inc., Weft integrates various tracking technologies, including Wi-Fi, BLE, GPS, satellite, and GPRS, to offer insights into logistics processes. The company's platform allows users to monitor and manage their assets, setting alerts for conditions such as location, temperature, and vibrations. By leveraging predictive analytics, Weft helps shippers anticipate potential bottlenecks by analyzing current locations and planned routes against historical data, enabling proactive adjustments to improve delivery timelines. The platform is accessible through web and mobile applications, and it collaborates with ERP providers, telecommunications companies, and logistics firms to extend its reach and capabilities within the industry.

Ntirety, Inc. specializes in database management services and cloud hosting solutions for businesses. Founded in 2001 and based in Dedham, Massachusetts, the company provides a range of services including remote database administration, database monitoring, backup assurance, performance tuning, and advanced database technologies. Additionally, Ntirety offers data consulting services such as database consolidation, migration, and compliance audits. The company distinguishes itself by integrating compliant security into its offerings, ensuring that businesses can manage security and compliance effectively. With over 20 years of industry experience, Ntirety operates three US-based security operations centers that support comprehensive risk management and data protection solutions. As a subsidiary of Hostway Corporation, Ntirety emphasizes creating resilient IT operations and providing a unified approach to security and compliance.