Creative Destruction Lab

The Creative Destruction Lab (CDL) is a seed-stage acceleration program founded in 2012 at the Rotman School of Management in Toronto, Canada. It is dedicated to supporting massively scalable, science- and technology-based ventures by providing a unique coaching process focused on specific objectives. CDL connects startups with experienced entrepreneurs and leading scientists across various sectors, including artificial intelligence, healthcare, quantum computing, blockchain, energy, and cleantech. The program has expanded its reach, operating in six cities: Vancouver, Calgary, Toronto, Montreal, Halifax, and New York City, and emphasizes the commercialization of scientific and technological advancements.

Malcolm Fraser

Associate

Dennis Kavelman

Founding Partner

Anthony Lacavera

Founding Partner

758 past transactions

Radom

Non Equity Assistance in 2022
Radom is a suite of crypto payment products that allow businesses to grow faster with APIs, Webhooks and a customisable SDK. Bringing zero chargebacks, blockchain scalability, and instantaneous settlement to the payments industry and empowering businesses to accept cryptocurrency payments from their customers.

frenter

Pre Seed Round in 2021
Online rental marketplace providing owners with all the tools they need to rent out items around their home and allows renters to rent out items in their city.

SunGreenH2

Non Equity Assistance in 2021
SunGreenH2 is a developer of breakthrough modular green hydrogen technology to transform hydrogen production. The company is building a ground-breaking, modular, high-efficiency electrolyzer system without using any platinum group novel, ground-breaking technology as a result of years of cutting-edge research and innovation in electrochemistry and nanomaterials to support a vision for decarbonized energy sources available globally at scale. SunGreenH2 was founded in 2020 and is headquartered in Singapore.

Arkangel AI

Non Equity Assistance in 2021
Arkangel AI is a company focused on improving global health outcomes by utilizing an artificial intelligence platform designed to detect preventable diseases quickly and accurately. By achieving a detection accuracy of 90%, the platform generates results in seconds, making it a scalable and cost-effective solution for identifying diseases, especially in remote areas with limited healthcare infrastructure. Founded in 2019, Arkangel AI aims to reduce the death rate from viral diseases by combining scientific advancements with community knowledge, ensuring that equal health conditions are accessible to everyone worldwide. The company operates offices in Canada and Colombia.

Finclude

Non Equity Assistance in 2021
Finclude offers financial well being services that empower EU citizens fair access to credit and expand the retail credit markets for financial institutions.

Nanology Labs

Seed Round in 2021
Nanology Labs has designed and is developing Manganescan®, a novel theranostic agent (MRI contrast agent/Radio-sensitizer) that allows detection of brain tumors at early stages using MRI. Simultaneously, it sensitizes cancer cells which improves radiation therapy outcomes. The agent is 3x more sensitive than current Gadolinium contrast agents (GBCAs), can cross the blood brain barrier and enables early and precise detection and targeting of brain cancer.
Stockholm Water Technology specializes in creating innovative and sustainable water purification solutions, focusing on capacitive deionization technology. The company combines advanced nanotechnology materials with smart engineering to develop a patented, membrane-free approach to water desalination. This technology is designed to achieve high water recovery rates while minimizing energy consumption and costs, making it a viable option for clients seeking efficient water cleansing and desalination methods. By integrating both hardware and software, Stockholm Water Technology enhances the overall functionality of its systems, promoting environmentally friendly practices in water management.

Milk Moovement

Seed Round in 2021
Milk Moovement is a Developer of a dairy supply chain management platform designed to track milk pick-ups and monitoring milk production. The company's platform is a comprehensive tool that tracks dairy production and quality by using a cloud-based web and mobile solution, giving users access to key information in real-time, enabling all supply chain stakeholders (producers, processors, transporters, testing labs, and cooperatives) to have access to milk performance metrics and in-depth information on current production, quality, and historical data right at their fingertips.

TrustLayer

Seed Round in 2021
TrustLayer is an insurtech solutions company that automates insurance verification with machine learning & AI and provides real-time updates on the R3 Corda distributed ledger ecosystem. TrustLayer helps companies eliminate error-prone, manual processes and streamline existing workflows to increase insurance compliance and decrease organizational risk. Customers in multiple billion dollar industries such as construction and property management rely on TrustLayer for its ease of use, tracking and verifying certificates of insurance & other business documents, increased vendor compliance, and the ability to utilize their platform for multiple use cases.

IntelliSports

Non Equity Assistance in 2021
IntelliSports is a Montreal based technology company that is combining real world sports with a digitally engaging experience and A.I. to create real world gaming.At IntelliSports they firmly believe that getting healthy should be as much fun as Levelling Up in your favourite video game. They are using their experience in Sports Analytics, Machine Learning, Video Games and mass market consumer technology to create a fitness platform where users can train, group up, compete and enjoy many of the most engaging elements of modern video games.

Arkion

Seed Round in 2021
SkyQraft AB specializes in aerial inspections of power lines using long-range drones equipped with advanced imaging technology. Founded in 2019 and based in Stockholm, Sweden, the company employs fixed-wing unmanned aircraft to survey electric grids, capturing comprehensive 360-degree views of power lines. This data is processed through a machine learning-based risk assessment system, enabling the identification of potential issues. When problems are detected, SkyQraft dispatches ground crews to address the repairs. The innovative use of drones and automated analytics positions SkyQraft as a leader in enhancing the safety and efficiency of power line maintenance in northern Europe.

PulSenics

Non Equity Assistance in 2021
PulSenics is a provider of real-time electrochemical system monitoring and control solutions. It utilizes artificial intelligence technology for electrochemical system monitoring and provides insights about electrolyte concentration, membrane health, power consumption, electrode adsorption, and others.

Remora

Non Equity Assistance in 2021
Remora offers technology innovations to solve challenging marine issues affecting marine conservation and sustainability. REMORA won first prize on Fishackathon Costa Rica 2016, in the framework of the global event endorsed by the US Department of State.

Hyivy Health

Non Equity Assistance in 2021
Hyivy Health creates an intelligent and holistic pelvic rehabilitation device for the 1 in 3 women worldwide who will experience a pelvic health complication in their lifetime. Our device provides the first quantifiable data set on the pelvic floor and 3 different therapies from multiple sensors and mechanical functions to help keep track of progress, adapt treatment plans and provide more effective, comfortable rehab experiences.

SpinDrive

Non Equity Assistance in 2021
Spindrive creates customized levitation technology pushing energy efficiency to the maximum level and promoting oil-free solutions.

AdHash

Non Equity Assistance in 2021
AdHash is a company based in Bulgaria that operates a decentralized protocol designed to enhance transparency and efficiency in the digital advertising marketplace. By eliminating ad tech middlemen, AdHash enables advertisers and publishers to manage their data directly on their servers, facilitating campaign setup, data analysis, and reliable targeting. The AdHash Protocol redefines the real-time bidding framework, incorporating first-party data to reduce ad fraud and ensure a more privacy-focused experience for users. This approach allows advertisers to gain greater control over their campaigns while providing users with enhanced privacy and browsing options.

Audio Design Desk

Non Equity Assistance in 2021
National Association of Broadcasters 2020 Best of Show Award Winner 2020 SXSW Innovation Awards Finalist 2020 Startupfest $100K Prize Top Tier 2020 SaaS Awards Shortlist Audio Design Desk is an AI-Assisted content creation tool that reinvents the process of connecting audio to video, turning hours of frustrating work into minutes of inspired fun. It is an entirely new breed of Digital Audio Workstation that artists can play like an instrument, revolutionizing how sound for video is produced, refined and delivered. Our powerful AI engine notices users’ likes and dislikes, so over time, Audio Design Desk gets to know each user’s taste. It comes bundled with over 20,000 sounds embedded with patent-pending Sonic Intelligence™, which makes our groundbreaking technology possible. Audio Design Desk’s intuitive and innovative content creation tools empower filmmakers, sound designers, composers, and creators to produce cinema-quality compositions at the speed of thought, giving them a level of creative control that is unmatched by any other software. Here’s how it works: Every sound in the add.app library is assigned identifying characteristics and carries an embedded sync point, which means that as sounds are previewed and chosen, they automatically land on the timeline in the exact right position relative to the video. The user simply imports a video file into the app and presses keys on their keyboard—H for hits, R for rises, D for drones, or users can assign sets of sounds to their numeric keys. The user can then strike the keys to position sound elements in real-time while watching the video playback—in effect, using the QWERTY keyboard like a Smart Sampler. For users who would rather select audio manually, add.app can search, audition and place sounds right from the timeline, completely eliminating the need to parse through libraries, import sounds and then find where they sync. Once a composition is set, add.app understands where sound connects to video and, by adjusting replacement criteria such as intensity, complexity, genre or feel, Audio Design Desk can use its Sonic Intelligence™ to instantly turn a single composition into infinite alternates without losing sync. Perhaps the most mind-blowing of all, add.app uses Artificial Intelligence (AI) and has built the foundation for Machine Learning (ML) to understand which sounds a user likes and which sounds they reject so, over time, add.app will learn and adjust to its user’s taste. add.app seamlessly integrates with the industry’s leading NLE software, including Adobe Premiere Pro, Apple Final Cut Pro, Apple Logic, DaVinci Resolve, Avid Pro Tools, and Avid Media Composer, with frame.io integration coming soon. add.app also works with hardware controllers like the Elgato Stream Deck, which makes the process of adding sound effects via keystrokes even easier. Audio Design Desk is a SXSW Innovation Awards Finalist and winner of a 2020 NAB Show / Pro Sound News Best of Show Award. Already being used by editors at Netflix, Hulu, and Amazon Prime Originals, add.app is fueling creativity everywhere. WHAT PEOPLE ARE SAYING Academy Award-nominated editor Matthew Cooke: “There isn't another piece of software that allows you to instantly create at this level of professionalism.” Sound Effects Editor of ZERO DARK THIRTY Jamie Hardt: “Audio Design Desk is the tool I’ve been looking for my entire career.” Mix Magazine: “Expertly designed,” “groundbreaking application that significantly speeds up the act of accurately adding sound effects and music to picture” ProAudioFiles: “A new paradigm for audio post production” Redshark News: “A breathtakingly effective idea for sound designers” Pro Video Coalition: “Represents an entirely new breed of Digital Audio Workstation—or DAW—that uses AI-assisted content creation tools to enable filmmakers, editors, sound designers and creators to produce cinema-quality sound in seconds"

Alan AI

Non Equity Assistance in 2021
Alan AI, Inc. is a Sunnyvale, California-based company that specializes in voice-based artificial intelligence solutions for enterprise applications. The company has developed the Alan Platform, which focuses on Spoken Language Understanding (SLU), enabling businesses to create, implement, and oversee conversational voice experiences within their applications. By facilitating seamless voice interactions, Alan AI aims to enhance user engagement and improve operational efficiency in various enterprise settings.

Continuum Industries

Non Equity Assistance in 2021
Continuum Industries Ltd is a technology company based in Edinburgh, United Kingdom, founded in 2018, that specializes in developing automation and optimization tools for the infrastructure sector. Its AI-driven software enables engineers and planners to enhance the design and delivery of infrastructure projects, including railways, roads, pipelines, and power lines. The platform allows users to automate their existing design processes while capturing extensive geospatial and engineering details. Central to its offering is a cloud-based optimization engine powered by evolutionary algorithms, which allows users to create custom design rules and maintain control over their projects. This innovative approach significantly reduces the time required for early-stage design work, supporting professionals in efficiently evaluating millions of design options to identify the most effective solutions.

Ascribe Bioscience

Non Equity Assistance in 2021
Ascribe Bioscience develops products that enable farmers to combat crop pathogens without negative impacts on the environment. The company is currently developing a seed treatment product that acts by boosting crops’ natural defenses.

Brilliant Matters

Non Equity Assistance in 2021
Brilliant Matters was created by passionate material scientists to answer the need for a reliable supply of a new generation of organic semiconductors. By using innovative chemical processes, we provide value-added and environmentally friendly solutions to emerging printed electronics technologies.

Moon

Non Equity Assistance in 2021
Moon Technologies, Inc. is a company based in Whitestone, New York, that operates a payment platform enabling the use of major cryptocurrencies for online purchases. The platform allows users to link their accounts or preferred wallets to facilitate transactions at various online retailers. It includes a browser extension that provides secure virtual cards tailored for consumer use, focusing on know-your-customer compliance. Additionally, the platform offers an application programming interface for card issuance, streamlining the shopping experience for users who wish to pay with cryptocurrency.

AdeptMind

Non Equity Assistance in 2021
AdeptMind is an AI company that innovates in e-commerce product discovery using active learning and deep learning. Its co-founders recently came out of a quite successful sale of their previous company, Maluuba. This time around, they are looking to grow a kick-ass Silicon Valley style team right here in downtown Toronto, Ontario, Canada.

Turbodega

Non Equity Assistance in 2021
TURBODEGA S.A.C. develops the mobile application platform for retailers and distributors to digitize and optimize the inventory and supply chains. Its platform uses artificial intelligence (AI) that automates orders, optimizes inventory using AI and tracks daily sales in real-time. TURBODEGA S.A.C. was incorporated in 2019 and is based in Santiago de Surco, Peru.

HazardHub

Non Equity Assistance in 2021
HazardHub aggregates risk data for addresses around the United States. HazardHub’s third-generation geospatial risk files are created by converting very large data sets of long-run hazard data into meaningful analog information that can be used to make informed decisions about the probability and severity of specific risks. The company aims to create the best geographic hazard data available and make it free for every person in the United States to see the risks around their property.

Labrador Systems

Non Equity Assistance in 2021
Labrador Systems is a robotics company building a new generation of personal robots to improve the quality of life for millions of people. They are taking the latest tech from those fields to create pragmatic but meaningful applications to support people in everyday life. The company driving the design and implementation of advanced robotics hardware and software systems. Labrador Systems is based in Oak Park, California, USA.

Kraken Sense

Non Equity Assistance in 2021
Kraken Sense develops an automated pathogen detection platform that includes sensors to detect bacterial contamination in real-time, using cutting edge nanotechnology and state of the art calibration techniques. The company's solution makes monitoring low-cost and easy to use with an IoT enabled dashboard and analytics tools.

AIKO

Non Equity Assistance in 2021
Aiko develops and commercializes algorithms based on Artificial Intelligence to increase the autonomy of satellite missions.

Hydromea

Non Equity Assistance in 2021
A scalable multi-robot inspection and sensing system that is permanently installed out at sea, or deployable from mobile autonomous crafts, and can be tasked remotely to carry out regular inspections, environmental measurements and emergency response. Focus is on portability, affordability and ruggedness (to withstand hostile underwater environment).

Compatio AI

Non Equity Assistance in 2021
Compatio LLC is a software company based in Springfield, Missouri, that focuses on developing solutions for dealers and merchants to sell customized products and services online, particularly in the realm of bicycle tools, gear, and components. Founded in 2016, Compatio specializes in eCommerce and recommendation systems, offering software that can be integrated into various web platforms and applications. Its technology enhances the online shopping experience by providing tailored product recommendations, which help increase transaction revenue and minimize product return costs. By connecting manufacturers, dealers, and consumers, Compatio aims to streamline the sales process and optimize inventory management for its clients.

Dive Technologies Inc.

Non Equity Assistance in 2021
Drift provides a roadmap of stitched content that streamlines your learning process using machine learning and AI.

Nectar Technologies

Non Equity Assistance in 2021
Nectar's mission is to ensure the health of honey bees by helping beekeepers apply the right care at the right time through bee-friendly and human technology. They aim to bring bees and beekeepers closer together by enabling communication between two species.w

Botlhale AI

Non Equity Assistance in 2021
Botlhale AI allows to build, train, test, and deploy multilingual conversational AI. Botlhale AI is a research and innovation start-up that specializes in conversational AI. Computer systems have become an integral part of everyday lives and as a result, natural spoken language is the desired form of human-computer interaction.

Circuit Mind

Non Equity Assistance in 2021
Circuit Mind Limited develops designing of electronic circuits using artificial technology. The design of electronic circuits includes features such as, faster magnitude and low cost. The company was incorporated in 2018 and is based in London, United Kingdom.

Opterrix

Non Equity Assistance in 2021
Developer of a software platform designed for insurers to identify and assess risk in real time. The company's cloud-based platform allows users to explore, visualize and access massive data sets in real-time by leveraging machine learning algorithms, enabling clients and organizations to decrease the latency in decision-making and maximize speed-to-value.

Inchfab

Non Equity Assistance in 2021
Inchfab specializes in custom microchip manufacturing, offering proprietary tools that cater to the microelectromechanical systems (MEMS) market. The company's microfabrication platform enables clients to prototype and produce low volumes of highly customized microchips economically. By focusing on the semiconductor and micromechanical Internet of Things (IoT) chip markets, Inchfab provides essential manufacturing capabilities that facilitate the design and production of specialized devices.

Diadem Biotherapeutics

Non Equity Assistance in 2021
Diadem Biotherapeutics is a biotechnology company that focuses on creating bio-therapeutical materials produced using organic means. Diadem develops exosomes to treat chronic inflammatory and auto-immune conditions.

BioHuntress Therapeutics

Non Equity Assistance in 2021
BioHuntress Therapeutics is a nature-inspired, scientifically validated, patent-protected drug development platform. BioHuntress was founded and incorporated in August 2016 and works in collaboration with advanced laboratories in Atlantic Canada. BioHuntress was born out of the desire to see valuable research being applied outside of academia. Its current long-term vision is to establish itself as a life science incubator that strives to bring academia-born inventions out of the lab and to the public.

DeepSpin

Non Equity Assistance in 2021
DeepSpin GmbH, founded in 2019 and headquartered in Berlin, Germany, specializes in the development of an innovative artificial intelligence (AI)-based magnetic resonance imaging (MRI) system. This next-generation imaging machine is designed to be significantly smaller, lighter, and more affordable than conventional MRI systems. By utilizing generative topological design for its hardware and deep learning algorithms for image processing, DeepSpin aims to enhance the accessibility of medical imaging, making it available to patients worldwide. The company's technology seeks to modernize medical imaging, providing a standard of care that can reach previously underserved medical domains.

DeepLife

Non Equity Assistance in 2021
DeepLife uses deep learning on multi-omics data to model cells and efficiently engineer their behavior. DeepLife is a biotech company with a mission to build the next generation of system biology. The company works in a highly collaborative translational manner, to facilitate the transition of discoveries from the laboratory to patients. The company operates through collaboration with academic groups in their respective areas of expertise.

Albus Health

Non Equity Assistance in 2021
Albus Health is a medical device company that develops a passive and non-contact, nocturnal symptom monitoring device. The company develops Albus Home RD, a completely passive and non-contact home monitoring device that enables a high quantity and quality of data from remote monitoring in research and clinical care.

XFlow Energy

Non Equity Assistance in 2021
XFlow Energy manufactures vertical-axis wind turbines (VAWTs) that reduce the cost of wind energy generation. XFlow Energy’s unique rotor design eliminates the structural failure modes common to VAWTs while simultaneously maintaining high efficiency and low manufacturing costs. XFlow also offers engineering consulting, prototyping, and testing services for renewable energy systems.

Modality.AI

Non Equity Assistance in 2021
Modality.AI, Inc. specializes in AI-driven healthcare screening solutions that focus on monitoring and assessing patients' health through conversational interactions. The company's platform utilizes audio-visual biomarkers and engages patients via dialogue and video to provide continuous health assessments. This technology is particularly beneficial for pharmaceutical companies, as it enhances the efficiency of clinical trials for therapies targeting neurological and mental health conditions. By analyzing multimodal data, Modality.AI delivers objective measures that correlate with clinical outcomes, facilitating self-driven neurological assessments. Founded in 2018 and headquartered in San Francisco, California, Modality.AI aims to improve health evaluations and streamline the clinical trial process.

Rise & Shine Technology

Non Equity Assistance in 2021
Rise and Shine is an interactive content platform that focuses on empowering GenZ. The platform features short-form video content, interactive challenges, and exciting real-world and digital rewards to be earned.

Ariel Precision Medicine

Non Equity Assistance in 2021
Ariel Precision Medicine, Inc. operates as an integrated genomics and digital health company that provides precision medicine solutions for the diagnosis, monitoring, and treatment of complex chronic diseases and disorders. It also offers ArielDx, a cloud-based clinical decision support tool that simplifies the diagnosis and treatment of pancreatic disease. The company was incorporated in 2013 and is headquartered in Pittsburgh, Pennsylvania.

ViroCarb

Non Equity Assistance in 2021
Virocarb is a science-driven biotech company focused on the development and commercialization of innovative drugs for viral infections with urgent unmet therapeutic needs.

Spark Thermionics

Non Equity Assistance in 2021
Spark Thermionics offers an energy-generation device that displaces conventional power production methods. The device utilizes heat-to-electricity converters that are based on thermionic energy conversion technology, can produce power from any fuel source at high efficiency, in a quiet package, and can scale from watts to megawatts, enabling people around the world to have cleaner, cheaper, and more secure electricity.

Iris Dynamics Ltd.

Non Equity Assistance in 2021
Iris Dynamics Ltd. is a privately-owned Canadian technology startup with headquarters on Vancouver Island, British Columbia, Canada. Iris has invented a process for magnetic force controlled actuator motors that improves the human-machine interface. This technology has been deployed in a diverse range of markets to help clients improve their processes that previously utilized low performance, less reliable, and more expensive technologies. The company is also using this technology to develop high performance stabilization platforms in several different client-led applications. Iris sponsors advanced theoretical and applied electromagnetic research at two major Canadian universities. Applications for our technology include aircraft controls, flight simulation, remotely piloted vehicles, heavy equipment, submersibles, automotive, industrial automation, robotics, platform/sensor stabilization, and semiconductor manufacturing. Iris Dynamics is actively seeking industry partners to advance this technology.

VYouPoint Aero

Non Equity Assistance in 2021
VYouPoint Aero is a start-up company that develops web applications for regional and low-cost airlines.

Alpenglow Biosciences

Non Equity Assistance in 2021
Alpenglow Biosciences, based in Seattle, Washington, specializes in advanced imaging technology for biological research. The company manufactures flatbed scanners designed for tissue analysis, which generate rich 3D molecular datasets. Its flagship product is an open-top light-sheet microscopy system that allows for the 3D scanning of intact biological samples, enhancing the capabilities of pathologists and researchers. Founded in 2018, Alpenglow aims to modernize pathology and improve the understanding of complex biological processes through its innovative imaging solutions.

Aquark Technologies

Non Equity Assistance in 2021
Aquark Technologies specializes in the development of compact cold-atom systems aimed at advancing quantum applications such as atomic clocks, sensors, and navigation systems. The company employs a unique laser geometry technique, stemming from over a decade of proprietary research at the University of Southampton, to miniaturize these systems to the size of a matchbox. This innovation enables the creation of plug-and-play quantum devices that offer portability and support the integration of quantum technologies into everyday life, paving the way for the next generation of quantum sensing and computing solutions.

Slingshot Simulations

Non Equity Assistance in 2021
Slingshot Simulations Limited owns and operates a simulation-as-a-Service platform. The company’s platform enables the rapid simulation of complex massive scale systems. The company’s software also provides tools for the automated configuration, deployment, management, and analysis of simulations. Slingshot Simulations Limited was founded in 2015 and is based in Leeds, United Kingdom.

Simporter

Non Equity Assistance in 2021
Simporter is an AI tool that predicts sales for products before they enter the market. With up to 93% accuracy, Simporter helps retailers & manufacturers sell the products that consumers want, by analyzing historical sales, social media sentiment, customer reviews, and micro-variables. On average, companies generate 12% more revenue with these predictions.

ECOncrete

Non Equity Assistance in 2021
ECOncrete Tech LTD. is a company based in Tel-Aviv, Israel, that specializes in developing and manufacturing innovative concrete products aimed at enhancing the ecological and biological value of coastal and marine infrastructures. The company's offerings include precast units, concrete additives, and ecological armoring units designed to protect against sea wave forces. Additionally, ECOncrete provides tide pools that mimic natural water ponds, enhanced sea walls that integrate with coastal infrastructure, ecological pile encapsulation as an alternative to standard methods, and bio-active walls that promote rapid plant growth on buildings. These products not only contribute to environmental sustainability but also offer structural benefits, increasing stability and longevity while reducing maintenance costs.

AdaViv

Non Equity Assistance in 2021
Urban (controlled) agriculture is on the rise! Vertical and Container farms are popping up here and there and there is increasing need to make urban agriculture more sustainable. AdaViv is a hardware-enabled, predictive agriculture company. Keeping “24/7 eyes on the plants”, our sensing and AI + computer vision uncovers hidden plant biometrics and translates data into actionable insights for growers. From disease prevention to rapid experimentation, improving yields and quality optimization, AdaViv helps producers grow smarter. Founded by an interdisciplinary team of MIT researchers and alumni, AdaViv recently emerged from MIT Delta V, the capstone entrepreneurship accelerator at MIT , and the MIT DesignX accelerator. In 2018, AdaViv was selected as one of the first grantees of Microsoft AI for Earth.

FTEX

Non Equity Assistance in 2021
FTEX Develops next-generation GaNFET based Electric Vehicle (EV) powertrains that extend the range and power of EVs by up to 30%.

Juvena Therapeutics

Non Equity Assistance in 2021
Juvena Therapeutics, Inc., a biopharmaceutical company, develops protein-based tissue rejuvenation therapeutics for elderly people. Its products are used for treatment of sarcopenia, wound healing, and neural regeneration. Juvena Therapeutics, Inc. was founded in 2017 and is headquartered in San Mateo, California.

MinervaAI

Non Equity Assistance in 2021
MinervaAI predicts who poses money laundering and terrorist financing risk to banks. We provide automated, accurate and audit-proof AML investigations at a fraction of the cost of compliance.

Nia Therapeutics

Non Equity Assistance in 2021
Nia Therapeutics, Inc. is focused on developing neurostimulation therapies aimed at treating memory impairment, particularly in patients who have suffered traumatic brain injuries. Founded in 2016 and based in Philadelphia, Pennsylvania, the company emerged from research at the University of Pennsylvania and was influenced by the United States BRAIN Initiative. Nia Therapeutics specializes in creating devices that analyze complex brain activity linked to memory function, delivering personalized therapy through deep-brain stimulation. This innovative approach seeks to enhance memory by restoring the brain activity essential for effective memory recall.

Connektica

Non Equity Assistance in 2021
Connektica offers telecommunications testing services solutions for RF component measurements in space and terrestrial applications. The company reduces test costs through the use of machine learning and offers decentralized traceability and diagnostic tool.

Aegiq

Non Equity Assistance in 2021
Aegiq Ltd. specializes in the development of semiconductor-based quantum photonic chips, utilizing III-V materials such as Gallium, Indium, and Arsenic. Founded in 2019 and headquartered in Sheffield, United Kingdom, the company focuses on creating technology that supports various applications, including broadband quantum communication, imaging, and scalable quantum computing. Aegiq's innovative platform employs a hybrid integrated photonics approach, facilitating economies of scale for quantum technology while enabling multi-million qubit operations. This positions Aegiq to offer a comprehensive range of products and systems in quantum cybersecurity, networking, and computing, significantly enhancing reliability and security compared to traditional silicon-based solutions.

Lucent Biosciences

Non Equity Assistance in 2021
Lucent Biosciences specializes in the development of innovative biofertilizers aimed at enhancing agricultural sustainability. The company offers a unique class of micronutrient fertilizers that promote higher crop yields and nutrient levels while being environmentally friendly. Their products are designed to improve soil health and sequester carbon, contributing to climate-positive farming practices. By utilizing sustainable bioactive crop nutrition, Lucent Biosciences enables farmers to cultivate nutrient-dense crops without polluting groundwater, thereby supporting regenerative agriculture and reducing overall costs per hectare.

Ki3 Photonics Technologies

Non Equity Assistance in 2021
Ki3 Photonics Technologies is an optical quantum technology that targets the generation and manipulation of non-classical photons, necessary for the development and commercial success of quantum technologies.

Renaissance Fusion

Non Equity Assistance in 2021
Developer of superconductors designed to make the stellarator simple, fusion electricity cheap and MRI a routine medical check-up. The company's high-temperature superconductors (HTS) for use in stellarator plasma devices and medical imaging, put fusion electricity in the grid, enabling clients to make the stellarator simple and fusion electricity cheap.

Navega Therapeutics

Non Equity Assistance in 2021
Navega Therapeutics is a preclinical stage company pursuing a radically different approach to treat chronic pain and tackle the opioid epidemic. At Navega, we have developed a novel gene therapy to treat severe chronic pain that is non-addictive, highly specific, and long lasting. We were inspired by nature: there are humans that have a mutation in their genome that feel no pain whatsoever. We have imitated this process by developing a novel gene therapy to target pain in a non-addictive way. In our proof of concept, we demonstrated that the mice that received our therapy have an increased pain tolerance and lower pain levels during weeks. We validated our approach in three preclinical animal models: inflammatory pain, chemotherapy-induced neuropathic pain and BzATP-induced pain. We also have safety studies demonstrating that our therapy has no neurological, motor, or olfactory side-effects. We have been awarded two SBIR grants, one from the National Cancer Institute and another one from the National Institute of Neurological Disorders and Stroke, and licensed three patents from UCSD.

Blue Ocean Gear

Non Equity Assistance in 2021
Blue Ocean Gear’s team of world-class submarine and rocket scientists designs and builds GPS tracking buoys capable of surviving the brutal operational demands of the modern fixed gear fisher. Our patented SmartBuoy product suite allows fishers to track and monitor data from their gear anytime and anywhere, enhancing operational efficiency and profitability by reducing both fuel costs and lost gear. Our products also directly address the environmental impacts of lost gear and entanglements.

LGN

Non Equity Assistance in 2021
LGN Innovations, Inc. specializes in developing artificial intelligence-based perception systems aimed at achieving human-level perception for autonomous systems. Founded in 2018 and headquartered in San Francisco, California, with additional offices in London and Zagreb, the company offers products such as LGN Auto-Calibrate, which integrates AI with sensor arrays, and LGN Intelligent Select, designed to efficiently filter and compress data. LGN's technology enhances the resolution and imaging capabilities of electronic devices, making it applicable across various sectors, including automotive, retail, and satellite industries. By optimizing data capture and processing, LGN's solutions reduce costs and power consumption while enabling high-level autonomy even with lower-cost sensors.

Unravel Biosciences

Non Equity Assistance in 2021
Unravel Biosciences develops a vertically integrated computational platform to improve drug discovery. Unravel’s platform screens many drugs in parallel for their real-world impact (e.g., the complete gene expression profiles and resulting physiological changes), reversing this process to identify the likely target(s) a drug is interacting with.

Altay Therapeutics

Non Equity Assistance in 2021
Altay Therapeutics Inc. is a biotechnology company dedicated to discovering innovative treatments for chronic inflammatory liver diseases and cancers. Founded in 2019 and based in San Bruno, California, the company specializes in developing small molecule therapies targeting transcriptional regulators known to drive various chronic conditions. Its research primarily focuses on curative therapies for diseases such as fibrosis, non-alcoholic steatohepatitis (NASH), rheumatoid arthritis, ulcerative colitis, and liver cancer. Altay's approach involves creating small molecules that inhibit the DNA interaction domain of transcriptional regulators, effectively turning off their target genes and addressing the underlying mechanisms of these diseases.

Yields.io

Non Equity Assistance in 2021
Yields NV operates as a disruptive model validation service provider. It develops and operates a model risk management platform that improves model test efficiency, coverage, and model accuracy. The platform engages in monitoring, regression testing, and model validation. The company was founded in 2017 and is headquartered in Ghent, Belgium.

AQT

Non Equity Assistance in 2021
AQT specializes in the development of quantum computer technology aimed at processing information through innovative methods. The company utilizes electric fields and single charged atoms trapped in vacuum chambers to create its quantum systems. Each quantum bit, or qubit, is represented by an ion and is manipulated and measured using precisely timed laser pulses. This technology provides clients with a clear pathway toward large-scale quantum computing solutions, ranging from scalable ion-trap processors to photonic networks that interconnect quantum computers. AQT's advancements position it at the forefront of the quantum computing landscape, offering significant potential for future applications.

InfiSense

Non Equity Assistance in 2021
For businesses that help buildings operate more efficiently, cost-effectively and sustainably, yet struggle to integrate wireless sensing into their workflow, we provide a remote, real-time wireless sensing platform that is purpose-built for their needs and drives down data collection and analysis costs, increases revenue, enables new service lines, and offers previously unavailable data for analytics. The InfiSense IoT platform leverages a revolutionary technology called LoRaWAN to provide our customers an unlimited selection of long-life wireless sensors, removes the pain of ingesting, organizing, securing, contextualizing and storing data in the cloud, and delivers data to any analytics application or business intelligence (BI) tool.

Capacitech Energy

Non Equity Assistance in 2021
Capacitech Energy is an energy storage component company that makes cable-based energy storage products such as the cable-based capacitor. The cable-based capacitor (CBC) can be easily customized, helps miniaturize electronics, reduce their cost, and compliment batteries to have a longer operating life. It was founded in 2016 and is headquartered in Orlando, Florida.

UnBound Chemicals

Non Equity Assistance in 2021
We're developing the technology and equipment to become the world's leaders in pharmaceutical ingredient recovery. ​ Pharmaceuticals enter the environment from all areas of the supply chain, from manufactures to patients. The active ingredients are very stable and often pass though waste treatment facilities intact. We have developed processes to capture and rework these products back into raw materials that can be reused by the pharmaceutical industry.

Bubo.AI

Non Equity Assistance in 2021
Bubo.AI Ltd, founded in 2019 and based in Middlesbrough, United Kingdom, specializes in developing software for customer value-based pricing. The company offers a price optimization platform that utilizes artificial intelligence to analyze customer behavior, determining their willingness to pay. This platform provides sales staff with recommendations for optimal pricing, enhancing their ability to meet profit targets efficiently. By tracking customer behavior over time, Bubo.AI aligns its optimization models to deliver dynamic pricing solutions tailored to both wholesalers and distributors.

Sublime Energie

Non Equity Assistance in 2021
Sublime Energie provides transportation of biogas.

Orbillion Bio

Non Equity Assistance in 2021
Orbillion Bio, Inc., a food-tech company, develops cultured meat products using a small tissue sample from heritage cattle breeds. It develops premium cell-based meat products from heritage cell lines that are directly sourced from farmers. The company was incorporated in 2019 and is based in Fremont, California.

HEARTio

Non Equity Assistance in 2021
Heart I/O is a digital diagnostic startup using artificial intelligence to help emergency providers identify heart abnormalities more quickly, more accurately, and for orders of magnitude less. It was started in 2018 and is headquartered in Pittsburgh, Pennsylvania.

Flox

Non Equity Assistance in 2021
Flox.ai offers machine vision and algorithms technology and software for broiler industry. It provides Flox-cam, offers images from multiple cameras streamed to office monitors and smartphones; FLOX-box, provides artificial intelligence processor; and FLOX-alert, a tracker that track smothering and bird activities. The company was founded in 2018 and is based in London, United Kingdom.

Neurolytic Healthcare Ltd.

Non Equity Assistance in 2021
Neurolytic Healthcare Ltd. is a company based in Oxford, United Kingdom, specializing in the design, development, manufacturing, and delivery of digital and genomic-based diagnostic tools and medical devices aimed at treating migraine and related neurological disorders. Established in 2016, the company focuses on personalized medicine by integrating genetic and biomarker data to enhance diagnostic accuracy and assist clinicians in determining optimal treatment strategies. Its product offerings include a diagnostic support tool, a pharmacogenetic test, and a mobile application designed for predicting migraine events. Through these innovative solutions, Neurolytic Healthcare aims to improve the management and treatment of neurological conditions.

Liberum Biotech

Non Equity Assistance in 2021
Liberum offers next generation protein manufacturing. Taking advantage of our suite of proprietary molecular and hardware technologies, we bring speed, scalability and cost reduction to disrupt current biologics manufacturing practices. Our vision is to democratize access to the fruits of synthetic biology.

Last Lock

Non Equity Assistance in 2021
Last Lock, founded in 2019 and based in Milwaukee, Wisconsin, specializes in manufacturing secure smart locks that enhance the functionality of traditional mechanical lock systems for homes and businesses. By integrating electronic sensors into smart cylinders, the company enables the scanning and storage of physical key profiles, allowing owners to manage, track, and grant access digitally. Last Lock's products offer various access methods, control over entry points, and self-powered battery cylinders, providing efficient installation solutions for users seeking improved security.

Total Flow Cannula

Non Equity Assistance in 2021
Total Flow Cannula is a novel, specialized tubing that ensures blood flow to a patient’s leg during extracorporeal circulation procedures. The new design enables surgeons to pursue preventive treatment or implement an immediate rescue strategy without additional devices or surgical procedures.

Quantum Dice

Non Equity Assistance in 2021
Quantum Dice is an award-winning spin-out from the University of Oxford specializing in quantum technology. The company develops quantum random number generators (QRNGs) that produce unbiased, true random numbers essential for modern communication technologies. These devices generate cryptographically secure random numbers that enhance security across various commercial applications. Quantum Dice's self-certified QRNGs are designed to function solely from quantum processes, ensuring improved encryption systems while safeguarding against external influences. This technology aims to provide enhanced security for an increasingly connected future.

BioForm Solutions

Non Equity Assistance in 2021
BioForm Solutions provides brands with an inexpensive and simple way to create a wide range of home compostable products. The company develops a series of unique extrusion printing devices that provide customers the freedom to rapidly create compostable products in the shape of films, tubes, and threads.

Watermarq

Non Equity Assistance in 2021
Watermarq specializes in providing data-driven insights focused on water security, utilizing artificial intelligence and machine learning to analyze satellite imagery. By extracting relevant information from this imagery, the company offers operational insights into environmental, social, and governance risks associated with large fixed-capital assets. This approach enables clients in both the public and private sectors to make informed estimates about future risks based on concrete observed data, rather than relying on speculation. Watermarq's services support investment decisions and collective actions aimed at enhancing water security, thereby addressing critical challenges related to resource management and sustainability.

Circadian Positioning Systems

Non Equity Assistance in 2021
Circadian Positioning Systems develops circadian solutions for optimizing performance in mission-critical scenarios.

DeepOpinion

Non Equity Assistance in 2021
DeepOpinion is delivering the future of text analysis/NLU for the industry. With DeepOpinion Studio and AutoNLU framework it is democratizing state-of-the-art natural language understanding for everyone - business users, developers and data scientists. DeepOpinion offers a growing library of pretrained models with world-leading accuracy as well as a range of tools to use them in production and create custom models - from DeepOpinion Studio and AutoNLU framework to an enterprise stack for on-premise deployments.

CyberOwl

Non Equity Assistance in 2021
CyberOwl Limited, founded in 2016 and based in Richmond, United Kingdom, specializes in developing network security software solutions. The company focuses on creating an innovative early warning system that employs real-time monitoring of high-value targets to detect malicious behavior. This technology, which is grounded in research shortlisted for a prestigious risk prize, addresses the increasing challenges posed by anonymous and persistent cyber threats, particularly in the context of Smart Cities and the Internet of Things. By utilizing a Bayesian-based framework, CyberOwl's system efficiently analyzes various indicators to identify potential security risks at an early stage, significantly reducing the processing overhead associated with monitoring extensive networks. The solution is designed to scale to networks with over one billion devices, enhancing visibility of threats and aiding in decision-making for countermeasures. CyberOwl is currently working on its minimum viable product and seeks strategic industry partners for validation and further development.

Magnomer

Non Equity Assistance in 2021
Magnomer is a manufacturer of novel magnetic inks for plastic packaging for the circular economy. It introduces Design2Recycle™, a revolutionary way of thinking about production. Central to their innovation are printable magnetizable inks: a design tool which allows consumer brands and manufacturers to enable better packaging recyclability without changes to manufacturing. It was founded in 2017 and is headquartered in Boston, Massachusetts.

Legit Fish

Non Equity Assistance in 2021
Legit Fish Company develops software tools and mobile applications for seafood products traceability and management. The company offers vessel hail and electronic vessel trip report (EVTR) applications, dealer/offloader system, and product verification labeling system. The company’s products provides third party product verification, traceability, and reporting services to ensure that the product meets all specifications and certifications associated with it. It serves seafood supply chain industry. The company was founded in 2018 and is based in Boston, Massachusetts.

Disa

Non Equity Assistance in 2021
Disa is an innovative materials liberation company providing solutions that optimize the world’s use of resources and radically disrupt best practices in the mining and reclamation industries. Disa utilizes patented liberation technology and other equipment to isolate targeted materials in order to deliver efficiencies, reduce costs, and mitigate environmental impacts to its users. Disa platforms isolate a vast array of geologic material ranging from precious and industrial metals, to hydrocarbons and abandoned uranium mine material.

HiGeorge

Non Equity Assistance in 2021
Reconnecting Labs is the creator of "HiGeorge", a civic action tool that empowers constituents to take action on issues that matter most.