Creative Destruction Lab

Rehabtronics is a technology development firm that focuses on solutions for physical rehab.

Developer of nanotechnology-based medical products intended to provide biocompatible and bio-selective wound dressings. The company commercializes nanotechnology in the health and decontamination sectors beginning with chronic wounds like diabetic foot ulcers, providing clinicians with small and mighty components to address unmet health needs.

Summit Nanotech Corporation is a business-to-business company based in Calgary, Canada, founded in 2018. It specializes in nanotechnology to develop innovative solutions for lithium extraction, aiming to optimize operations for lithium producers while minimizing environmental impact. The company's patented extraction technology is designed to deliver economically competitive, battery-grade lithium, addressing the industry's demand for sustainable practices. By focusing on modular commercial systems, Summit Nanotech seeks to upscale and commercialize its advanced concepts in lithium extraction, positioning itself as a leader in the energy development sector.

4pi Lab specializes in early wildfire detection, geolocation, and monitoring solutions aimed at mitigating the impacts of catastrophic wildfires. The company leverages its proprietary services platform and the EPiC satellite constellation to provide real-time detection and monitoring of wildfires with exceptional accuracy, offering AI-alerted reporting at a resolution of 5 meters. This technology enables organizations to identify very small fires quickly, facilitating data-driven responses within minutes and addressing the growing global wildfire epidemic. By employing advanced satellite technology, 4pi Lab aims to enhance the effectiveness of wildfire management and response efforts.

Path Therapeutics, Inc. develops a novel neurometabolic, phenotypic drug discovery platform that lifts the hood of the cell and identifies novel targets to jump-start stalled drug discovery programs. The company through its phenotypic-screening technology screen repurposed libraries for which the molecular target is well-characterized to enable reverse identification of druggable proteins. The platform enables drug discovery across CNS disorders, including epilepsy, autism, and aging. Path Therapeutics, Inc. was incorporated in 2013 and is based in Calgary, Canada.

Developer of an imaging and medical platform designed to revolutionize the effective and non-invasive vitreoretinal treatments of various eye diseases. The company's platform leverages advanced imaging technology, embedded machine learning and laser technology to diagnose, plan, and treat diseased areas within the eye such as age-related macular degeneration, diabetic retinopathy, branch retinal vein occlusion, and glaucoma, enabling patients to reduce disease progression and receive effective treatment options get a cure for retinal diseases.

Developer of cryopreservation system designed to preserve small molecules used in clinical research and studies. The company designs and manufactures patented ice recrystallization inhibitors for use in the cryopreservation of cells, and tissues that maintain cellular function after extended frozen storage, thereby enabling physicians to use less costly storage and transportation systems for cell therapeutics.

Developer of a data management platform designed to help the energy industry optimize its emission reduction strategies. The company's platform focuses on enterprise management of methane data, collating and synthesizing data from any emissions sensor, automatically generating regulatory compliance reports, and suggesting steps to reduce pollution, enabling energy firms to gain insights into methane measurement data, and emissions reductions at lower costs.

Bidali is a payment platform that facilitates next-generation payments for businesses of all sizes, enabling them to accept digital currencies. The platform employs proprietary blockchain technology to enhance security and inclusivity in the financial system. It provides developer-friendly APIs and e-commerce plugins for seamless integration of digital currency payments into applications and websites. Additionally, Bidali offers a mobile wallet that allows users to easily send, receive, and store cryptocurrencies. Users can also purchase gift cards for online and in-store transactions, with cashback incentives that can be reinvested in further purchases. This approach helps businesses increase sales while reducing fraud risks associated with traditional payment methods.

Developer of a technology-based platform designed to enhance performance via sustainable and economic carbon nanofibers. The company's platform has developed a proprietary chemical process technology to convert carbon dioxide and waste heat from power plants into high-strength carbon fiber, enabling industries to use greenhouse gas feedstocks annually and turning them into sustainable and valuable solid commodities.

EnviCore is an innovative research and development company focused on sustainable wastewater treatment solutions, particularly in the context of mining operations. The company has developed technologies that aim to transform the treatment of mining tailings, offering environmentally friendly and cost-effective alternatives that enhance performance and efficiency. By utilizing low-cost, eco-friendly reagents, EnviCore's solutions can be seamlessly integrated into existing tailings treatment facilities, thereby reducing the demand for freshwater resources. This approach not only minimizes the environmental impact associated with mining waste but also supports mining operators in pursuing resource development in a more responsible manner.

Provision Analytics Inc., founded in 2018 and headquartered in Calgary, Canada, provides a cloud-based solution designed to enhance food safety by tracing and tracking food products throughout the supply chain. The company's software automates food safety processes for food processors and manufacturers, significantly minimizing the time required for data input and recall procedures. By linking detailed process data with production results, Provision Analytics generates analytics that help reduce food loss and improve product quality.

Copperstone Technologies specializes in providing innovative solutions for large mining companies to manage the liabilities and safety costs associated with tailings ponds. The company has developed a specialized field robot, known as HELIX, which can safely access tailings ponds to deploy sensors and sampling payloads. This technology minimizes human risk by keeping personnel out of hazardous areas, while also enhancing operational efficiency and reducing costs. Additionally, Copperstone's expertise in electrical and mechanical design, along with advanced robotic systems, allows it to offer robotics-as-a-service for data collection in remote or dangerous environments. This capability enables clients to monitor the performance of their equipment effectively, ensuring operational integrity in challenging locations.

Convrg is a company focused on providing remote power generation services aimed at enhancing environmental sustainability in the Canadian upstream oil and gas sector. By developing innovative power generation and air compression packages, Convrg eliminates methane venting and complies with stringent methane regulations. Their technology offers an efficient solution for power and instrument air, which helps operators reduce both capital and operating costs. Through its services, Convrg addresses the challenges faced by businesses in remote locations while promoting a more sustainable approach to energy generation.

DrugBank is a comprehensive online database that contains information on drugs and drug targets. They organize, collect, and curate all the important information about drugs into a single unified resource. It also combines detailed drug such as pharmacological, pharmaceutical, and chemical data with the comprehensive drug target sequence, structure, and pathway information. DrugBank is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students, and the general public. It was founded in 2015 and is headquartered in Edmonton, AB, USA.

Smart Access Inc. is a Canadian company based in Edmonton, Alberta, founded in 2015, that specializes in designing and developing knowledge-based system software aimed at enhancing workforce efficiency in retail and warehouse environments. The company's platform offers a range of software services that include onboarding, user management, content management, mobile experience building, integrated applications, and operational intelligence. Smart Access focuses on providing employers with essential insights into workforce performance through intuitive, on-demand access to critical information, thereby facilitating improved competence and productivity among employees.

G2V's founding mission is to develop and commercialize technology that will enable food production for a growing population while significantly reducing fresh water and land use. We do this by improving yield, quality, and operating costs for commercial growers by providing efficient 'engineered sunlight'​. Our advanced technology provides greenhouses, vertical farms, and home growers with multi-zone lighting and plant monitoring, allowing a grower to keep tabs on their entire crop. We are obsessed with using new technology to make a difference and continue to develop some of the most dynamic and innovative new products for the horticulture market.

Producer of gourmet mushrooms intended to offer several varieties of oyster mushrooms and are continuously testing new species. The company uses wasted brewery and agricultural byproducts as a growing medium for specialty mushroom cultivation and operates on a truly sustainable and circular model, supporting local breweries, chefs, food processors, and ranchers, enabling clients to get sustainable food.

Developer of downhole tools designed for multistage completions in unconventional oil and gas wells. The company's tools enable oil and gas producers to access multiple well sections from a single wellbore, enabling businesses to reduce drilling costs and environmental impact by minimizing the surface footprint required for well development.

Developer of a real-time IoT (Internet of Things) broadband seismic and vibration remote sensing system designed to provide critical insights to support earthquake monitoring, microseismic monitoring, critical infrastructure monitoring, proactive maintenance, and efficient operation optimization. The company's system combines sensor hardware, connectivity, and data analysis components to provide real-time wireless remote data, enabling earthquake and impact assessment, infrastructure, facility, and machinery industries to provide high-accuracy high-resolution insights, without the need for infrastructure, power, cables, on-site operations.

CleanO2 Carbon Capture Technologies is set to change the heating industry. In 2007, the founders of CleanO2 CCT began developing technology that would have a positive impact in the industry. Now, 9 years later, the company have deployed the residential carbon capture device in Alberta, Canada and have expanded the technology on a global scale. The company has developed an aggregated commercial carbon capture device called CARBiNX, a sleek, carbon munching addition to businesses. Reducing energy demands through heat recovery and using the carbon capture process to create a valuable by-product. CleanO2 Carbon Capture Technologies was founded on 2013 and is headquartered in Calgary, Alberta, Canada.

Fluid Biomed Inc. is a Calgary-based company that specializes in the development of innovative implantable vascular stents aimed at enhancing patient well-being. Established in 2012, the company focuses on creating a stent designed to gently divert blood flow away from brain aneurysms, facilitating their healing process. Through its commitment to innovation, Fluid Biomed seeks to improve health outcomes and overall quality of life for patients.

Developer of a health technology company delivering precision datasets from the gastrointestinal tract leveraging a capsule sampling technology and creating a paradigm shift in how GI health is diagnosed and treated. The company's product enables passive sampling of small bowel luminal fluid to leverage intestinal data to provide insights, enabling healthcare providers with direct sampling and analysis of targeted regions of the gastrointestinal tract.

Wyvern Incorporated, founded in 2018 and based in Edmonton, Canada, specializes in the manufacturing of hyperspectral satellites designed for earth observation. The company's satellites are compact yet deliver high spatial resolution and superior spectral content. This technology allows various industries, including agriculture, forestry management, and environmental monitoring, to capture detailed image data across multiple bands. By providing affordable access to this advanced data, Wyvern enables organizations to make informed decisions more efficiently.

Eavor Technologies Inc. is a geothermal technology company based in Calgary, Canada, founded in 2017. It focuses on creating a clean and reliable energy future through its innovative Eavor-Loop™ system, which extracts heat from deep within the Earth for commercial heating and electricity generation. This system employs advanced drilling techniques and integrates existing commercial components in a novel configuration, allowing for scalable and steady green power production. Eavor's technology circulates a benign working fluid in a closed loop, isolating it from the environment while harvesting heat from geologically accessible rock temperatures. The company also operates the Eavor-Lite™ Demonstration Project as a prototype for its technology suite, addressing challenges traditionally associated with geothermal energy.

EnerSoft Inc. develops and offers real optimization software that automates well placement and scenario planning directly in petrel. was founded in 2013 and is headquartered in Calgary, Canada.

Synthiam is an industry-defining robot software development and technology distribution platform for everyone, regardless of previous software programming experience. Our customers include R&D PoC, DIY, enterprise businesses, manufacturers, and educational institutions. Synthiam's platform focuses on the democratization and distribution of technologies to be effortlessly added to robots. It is our mission to democratize robotics by making robot programming easy and accessible to anyone with an idea. Synthiam's software products give the power of easy robot programming tools to the hands of everyone; paving the way for a safer and healthier future of robot products.

At True Angle, we want to help people break perceived barriers, feel great, and find joy in the life they are living. For people who have lost the ability to eat because of a swallowing disorder, the Mobili-T is the first mobile device that they will actually be able to take home with them so that they can complete their exercises wherever and whenever they like, all through an engaging app that provides feedback on how hard and how long their muscles are contracting, and how close they are to meeting the specific targets set for them by our “smart” software. True Angle Medical Technologies is an Alberta-based privately held corporation located in Edmonton, Alberta, Canada.

Systolik Digital Health is a medical device manufacturer providing solutions for cardiologists.

Orpyx Medical Technologies Inc. specializes in the development of mobility sensor devices aimed at diabetic patients. The company's flagship product, the Orpyx SI sensory insoles, utilizes advanced sensor technology to monitor pressure, temperature, and movement, thereby aiding in the management and prevention of diabetic foot ulcers and limb loss. In addition to the insoles, Orpyx offers Kinetyx, a mobile in-shoe pressure management system that collects clinical plantar pressure data for applications in sports medicine, therapeutic interventions, and footwear design. Another product, SurroGait Rx, is designed to enhance mobility and balance for multiple sclerosis patients suffering from loss of protective sensation in their feet. Founded in 2010 and headquartered in Calgary, Canada, Orpyx Medical Technologies is committed to empowering individuals with diabetes to maintain their mobility while promoting a prevention-focused healthcare approach.

EZ-Robot Inc. is a Canadian company founded in 2011, specializing in an integrated robotics and IoT platform designed to facilitate learning in technology and robotics. The company targets a wide audience, ranging from middle school students to industry professionals, offering educational tools that support STEAM (Science, Technology, Engineering, Arts, and Mathematics) concepts. By using robotics as a means to impart practical knowledge, EZ-Robot aims to inspire lifelong learning and problem-solving skills. The company's focus is on providing creative and accessible content that enhances the educational experience, encouraging students to engage with technology through innovative applications.

TikTiks operates a fan-to-fan secondary ticket marketplace designed to enhance the buying and selling experience for ticket holders. The platform aggregates tickets from trusted season ticket holders, local businesses, and reputable ticket brokers, allowing users to transact safely on mobile devices. With a focus on no-fee ticketing and mobile-only distribution, TikTiks facilitates direct transactions between fans. The team behind TikTiks has extensive experience in ticketing technology and is currently developing a blockchain-enabled system aimed at ensuring secure and transparent transactions across various market segments, including B2B, B2C, and P2P. The recently launched Smartiks platform further empowers venues, promoters, and entertainers by capturing value and data from after-sale transactions, ensuring that all stakeholders benefit from dynamic ticket pricing.

Carbon Upcycling Technologies (“CUT”) was formed to use the pollution of today to build the materials of tomorrow by converting CO2 gas into solid products. CUT sells advanced solid products derived from greenhouse emissions and cheaply available solids. Since 2014, CUT has scaled its ability to capture CO2 emissions from point sources, such as power plants, by over a million times and has technically validated the performance of its end products in over 10 different industrial markets. Through its portfolio of CO2-derived solid nanoparticles, CUT has technically validated its solutions for use in the plastics, coatings, epoxy, adhesives, concrete, lithium-ion battery, and pharmaceutical industries. CUT commercialized a corrosion-resistant coating, utilizing its nanoparticles, in 2017, becoming the youngest CO2 utilization company to generate commercial revenue (<2.5 years since inception) and has since been confirmed as one of the top CO2 utilization companies in the world as one of the 10 Carbon X-Prize Finalists. CUT has been named as a Solar Impulse Efficient Solution label recipient, a funding recipient of Fundación Repsol Entrepreneurs Fund, and a winner of the 2019 76West Clean Technology Competition.

SensorUp Inc. is a Calgary-based company established in 2011 that specializes in developing and operating an Internet of Things (IoT) platform. The company provides solutions for sensor data, analytics, and mapping through a unified API, enabling the interconnection of IoT devices, data, and applications over the web. The SensorUp IoT Software Platform facilitates integration with the SensorUp Cloud, allowing devices to communicate with one another and with third-party web applications. Among its offerings is the Smart Cities Starter Kit, designed for air quality monitoring. SensorUp aims to empower users by enabling intelligent automation and enhancing safety and productivity in various sectors.

Unsist is a predictive analytics company creating technology for the oil & gas industry that never stops. It is composed of a team of international scientists and engineers, part of the NextAI Program, a global innovation hub for artificial intelligence. The program is partnered with Next Canada, Google Canada, IBM Canada, and NVIDIA to leverage Canada's leadership position in artificial intelligence.

Zept is a company focused on assisting international students in finding suitable educational institutions in Canada. By utilizing a search engine that indexes various university and college programs, Zept enables students to input their high school grades and preferred fields of study. The platform then recommends universities that align with the students' academic profiles and aspirations, thereby enhancing their chances of gaining admission to desirable schools. This service is designed to simplify the process of selecting the right educational path for students seeking higher education in Canada.

Swirltex Inc. specializes in the design and supply of custom wastewater treatment systems for various applications, including wastewater treatment, produced water treatment, dairy processing, mining wastewater, and beverage clarification. Founded in 2015 and located in Calgary, Canada, Swirltex utilizes a patented membrane technology that separates solids and liquids based on buoyancy. This innovative approach enables the treatment of water that would otherwise be deemed unusable, allowing for enhanced production while minimizing environmental pollution. By effectively manipulating the buoyancy of different contaminants, Swirltex provides efficient solutions for complex water treatment challenges.

Terrapin Geothermics focuses on harnessing heat to create profitable energy solutions, specifically targeting industrial waste heat and deep geothermal resources. By employing advanced technology and expertise, the company maps available waste heat and aligns it with state-of-the-art technologies to generate emission-free energy. Terrapin's approach not only helps industries optimize their processes but also supports their transition to a net-zero world. The company builds robust financial models to facilitate sound investment decisions, enabling clients to leverage renewable energy sources effectively while enhancing their environmental, social, and governance (ESG) commitments. Through these initiatives, Terrapin aims to drive value for its clients and partners in an increasingly challenging economic landscape.

Interface Fluidics is an international technology company that specializes in reservoir fluid analysis services. Utilizing a proprietary nanofluidic technology platform, the company provides innovative solutions for oil and gas producers to enhance their understanding of reservoir properties. By focusing on microfluidic reservoir modeling and fluid characterization, Interface Fluidics evaluates the effectiveness of new processes and fluid interactions. This comprehensive analysis helps clients make informed production decisions and ultimately aims to optimize oil production and increase overall productivity in the industry.

Vivametrica Ltd. is a Calgary-based company that specializes in predictive health data analytics by analyzing information from wearable sensor devices. Founded in 2013, Vivametrica provides businesses with tools to assess health and wellness programs through its vBioAge application, which determines biological age based on physical attributes and lifestyle, and vScore, which measures overall health. The company offers health intelligence solutions for various sectors, including insurance, health providers, and device manufacturers. Its platform enables standardized data collection and management, facilitating actionable insights for consumers, enterprises, healthcare professionals, and researchers. Additionally, Vivametrica provides the InteractiveRisk Tool, which calculates combined risk for various health conditions. The company operates as a subsidiary of SPROUT Wellness Solutions Inc. as of August 2020.

KRS Biopharma

ReWatt Power Inc. develops and operates sensor to cash platform that helps users to manage their generation assets. The company's platform utilizes site aggregation for smaller generators, along with their proprietary distributed ledger (blockchain) technology, to transact on any service – saving significant time, costs and effort throughout the full-cycle process. ReWatt Power Inc. was founded in 2016 and is based in Calgary, Canada.

Neuraura Biotech Inc., founded in 2017 and based in Calgary, Canada, focuses on developing neuro sensors for neuro-modulation and brain-machine interfacing to assist individuals with neurological, psychiatric, and sensory disorders. The company’s flagship product is a brain monitoring platform designed for epilepsy surgery, which integrates proprietary electrodes, wireless EEG hardware, and 3D visualization software. This platform aims to enhance patient experiences and outcomes while alleviating the workload of clinicians and reducing healthcare costs. In addition to its work in epilepsy, Neuraura is utilizing its advanced micro-electrodes to explore personalized bio-electronic medicine, targeting conditions such as polycystic ovary syndrome to improve women's metabolic and reproductive health through wearable devices. By leveraging unique electrophysiological data from patients, Neuraura seeks to advance the field of neuromodulation for broader applications.

Roshan Water Solutions is a spinoff company out of the University of Alberta. Their aim is to provide safe, clean water while protecting the environment.

VizworX Inc. is a custom software development company based in Calgary, Canada, established in 2012. The firm specializes in creating tailored interactive visual solutions, including virtual reality, augmented reality, and mixed reality applications that enhance immersion and communication. VizworX also offers artificial intelligence services, focusing on facial recognition, data management, site security, and business optimization. Their expertise extends to data visualization, web and mobile application development, and the creation of dynamic information exchanges that facilitate better engagement with data. By leveraging advanced technology, VizworX aims to improve operational efficiencies, enhance team communication, and support informed decision-making for organizations across various sectors.

Cohesic is a developer of a Care Intelligence Platform that aims to enhance clinical decision-making and patient care, particularly in cardiovascular health. The platform utilizes data-driven insights to streamline diagnostic workflows and structured reporting. By equipping diagnostic test providers and clinicians with tools that improve reporting efficiency and reduce medical errors, Cohesic facilitates a deeper understanding of patients' health conditions. This focus on efficiency and accuracy in cardiovascular care positions Cohesic as a key player in advancing healthcare technology and improving patient outcomes.

Ingu Solutions Inc., based in Calgary, Canada, specializes in the development of miniaturized mobile sensors designed for pipeline inspection. The company has introduced Pipers, an innovative screening tool that identifies risks and performance issues in pipelines. This technology is capable of detecting and locating leaks, geometric defects, magnetic anomalies, and deposits in pipelines as small as 2 inches in diameter. By facilitating inline inspections that can occur more frequently and at a lower cost, Ingu Solutions addresses the challenges posed by aging pipeline infrastructure and the limitations of traditional inspection methods. Their self-serve inspection model significantly reduces engineering and downtime costs, making pipeline integrity programs more accessible for a diverse range of clients. Ingu Solutions' approach enables continuous access to real-time condition-critical data, empowering clients to enhance their planning and decision-making processes.

FREDsense is a Canadian company founded in 2014 and headquartered in Waterloo. It specializes in manufacturing portable testing kits designed to detect water-borne chemicals and contaminants, including arsenic, iron, manganese, and acidity. The company’s flagship product, FRED, combines biology and engineering to provide autonomous, electrochemical outputs that utilize genetically engineered bacteria for sensing heavy metals and other pollutants. FREDsense also offers custom field-based solutions tailored to specific monitoring needs of its clients, enabling environmental consultants and engineers to efficiently and cost-effectively analyze water quality.