Upstate Carolina Angel Network

The Upstate Carolina Angel Network (UCAN) is a consortium of accredited investors based in Greenville, South Carolina, dedicated to investing in and supporting start-up and early-stage high-growth businesses in the Southeastern United States. Established in 2008, UCAN aims to foster entrepreneurship and innovation by providing financial resources and mentorship to emerging companies. The network focuses on identifying promising ventures and facilitating their growth, contributing to the economic development of the region.

J.B. Holeman

Co-Founder

Past deals in South Carolina

Friyay

Seed Round in 2019
Friyay.io is the next-generation collaboration platform for remote and flexible teams. Friyay turns remote working into an engaging social experience, with flexible, customizable tools, integrated information management, and real-time collaboration - all in one platform.

Proterra

Series F in 2017
Proterra Inc. designs and manufactures zero-emission electric buses, specializing in heavy-duty vehicles that enable fleet operators to reduce operating costs and eliminate fossil fuel dependency. The company’s product lineup includes 35-foot and 40-foot Catalyst transit vehicles, which are built to meet the diverse mileage needs of urban and regional routes on a single charge. Proterra also provides a range of services, including pre-delivery consultations, training programs, mid-life inspections, and battery management services. Their offerings extend to energy services such as fleet planning, charging infrastructure, and telematics. Founded in 2004 and headquartered in Burlingame, California, Proterra has additional offices in South Carolina and California, and its products are designed, engineered, and manufactured in the United States. By helping customers transition to battery-electric transit solutions, Proterra has contributed to significant reductions in greenhouse gas emissions and fuel consumption.

Proterra

Series E in 2017
Proterra Inc. designs and manufactures zero-emission electric buses, specializing in heavy-duty vehicles that enable fleet operators to reduce operating costs and eliminate fossil fuel dependency. The company’s product lineup includes 35-foot and 40-foot Catalyst transit vehicles, which are built to meet the diverse mileage needs of urban and regional routes on a single charge. Proterra also provides a range of services, including pre-delivery consultations, training programs, mid-life inspections, and battery management services. Their offerings extend to energy services such as fleet planning, charging infrastructure, and telematics. Founded in 2004 and headquartered in Burlingame, California, Proterra has additional offices in South Carolina and California, and its products are designed, engineered, and manufactured in the United States. By helping customers transition to battery-electric transit solutions, Proterra has contributed to significant reductions in greenhouse gas emissions and fuel consumption.

Atlas Organics

Seed Round in 2015
Atlas Organics Inc. specializes in organics recycling, focusing on the collection and processing of food and yard waste to create organic garden products. Founded in 2013 and headquartered in Spartanburg, South Carolina, the company operates in various regions, including San Antonio, Texas, and parts of South Carolina, North Carolina, and Tennessee. Atlas Organics collaborates with municipalities and serves a diverse clientele, including grocery stores, hospitals, schools, and restaurants, to promote sustainability and divert compostable waste from landfills. By facilitating the transformation of food waste into valuable compost, the company supports agricultural and landscaping applications, contributing to healthier soil and promoting the “table to farm” movement.

ActivEd

Seed Round in 2015
ActivEd, Inc. is an ed-tech company based in Greenville, South Carolina, that specializes in providing interactive online lessons designed to enhance educational standards in the United States. The company offers Walkabouts, which are engaging, movement-rich activities that transform fundamental concepts in math, language, and literacy into short lessons for Pre-K through Second Grade students. These research-based online tools enable teachers and parents to create dynamic lessons that incorporate physical activity, making learning both fun and effective. Additionally, Walkabouts align with state standards, facilitating seamless integration into existing lesson planning for educators. Founded in 2011, ActivEd aims to enrich the educational experience by making foundational learning more interactive and accessible.

The Iron Yard

Series A in 2014
The Iron Yard LLC is an accelerator based in Greenville, South Carolina, focused on seed and startup investments in technology, particularly in sectors such as healthcare, biotech, software, energy, and mobile technology. Founded in 2011, it offers a three-month program that typically accepts ten companies, providing an initial investment of $20,000, with the possibility of follow-up funding up to $1 million. The Iron Yard seeks to support teams of two or more founders, although solo founders may also be considered. The firm takes a six percent equity stake in the companies it funds. Additionally, The Iron Yard Academy provides intensive coding education across multiple campuses, aimed at developing skilled junior-level programmers with a focus on both technical abilities and character development. Through mentorship and education, The Iron Yard aims to address the growing demand for skilled professionals in the technology sector while fostering a community that encourages innovation and collaboration.

The Iron Yard

Series A in 2014
The Iron Yard LLC is an accelerator based in Greenville, South Carolina, focused on seed and startup investments in technology, particularly in sectors such as healthcare, biotech, software, energy, and mobile technology. Founded in 2011, it offers a three-month program that typically accepts ten companies, providing an initial investment of $20,000, with the possibility of follow-up funding up to $1 million. The Iron Yard seeks to support teams of two or more founders, although solo founders may also be considered. The firm takes a six percent equity stake in the companies it funds. Additionally, The Iron Yard Academy provides intensive coding education across multiple campuses, aimed at developing skilled junior-level programmers with a focus on both technical abilities and character development. Through mentorship and education, The Iron Yard aims to address the growing demand for skilled professionals in the technology sector while fostering a community that encourages innovation and collaboration.

The Iron Yard

Series A in 2014
The Iron Yard LLC is an accelerator based in Greenville, South Carolina, focused on seed and startup investments in technology, particularly in sectors such as healthcare, biotech, software, energy, and mobile technology. Founded in 2011, it offers a three-month program that typically accepts ten companies, providing an initial investment of $20,000, with the possibility of follow-up funding up to $1 million. The Iron Yard seeks to support teams of two or more founders, although solo founders may also be considered. The firm takes a six percent equity stake in the companies it funds. Additionally, The Iron Yard Academy provides intensive coding education across multiple campuses, aimed at developing skilled junior-level programmers with a focus on both technical abilities and character development. Through mentorship and education, The Iron Yard aims to address the growing demand for skilled professionals in the technology sector while fostering a community that encourages innovation and collaboration.

Proterra

Series C in 2014
Proterra Inc. designs and manufactures zero-emission electric buses, specializing in heavy-duty vehicles that enable fleet operators to reduce operating costs and eliminate fossil fuel dependency. The company’s product lineup includes 35-foot and 40-foot Catalyst transit vehicles, which are built to meet the diverse mileage needs of urban and regional routes on a single charge. Proterra also provides a range of services, including pre-delivery consultations, training programs, mid-life inspections, and battery management services. Their offerings extend to energy services such as fleet planning, charging infrastructure, and telematics. Founded in 2004 and headquartered in Burlingame, California, Proterra has additional offices in South Carolina and California, and its products are designed, engineered, and manufactured in the United States. By helping customers transition to battery-electric transit solutions, Proterra has contributed to significant reductions in greenhouse gas emissions and fuel consumption.

Selah Genomics

Seed Round in 2013
Selah Genomics Inc. is a clinical diagnostic specialist based in Greenville, South Carolina, that provides advanced molecular and genomic diagnostic services to healthcare providers and the pharmaceutical industry in the United States. Founded in 2006 and originally known as Lab21 Inc., the company focuses on enhancing diagnostic testing services particularly in women's health and personalized cancer treatment. Its offerings include molecular diagnostic testing, assay validation, and genomic profiling, which assist clinicians in treating and monitoring patients. Selah Genomics specializes in various areas such as next-generation sequencing, companion diagnostics, RNA sequencing, targeted sequencing, and bioinformatics. The company's services are designed to support early-stage drug development, clinical trials, and regulatory processes, thereby contributing to improved patient outcomes.

Pandoodle

Venture Round in 2013
Pandoodle Corp. specializes in video and imaging solutions that enhance the value of advertising. The company provides a Software-as-a-Service platform known as Dolo, which automates the analysis and dynamic insertion of branded content into videos and photos. This technology enables advertisers and publishers to achieve personalized branding in real-time, thereby increasing the effectiveness of their marketing efforts. Founded in 2008 and headquartered in Lexington, South Carolina, Pandoodle also has offices in major locations such as Silicon Valley, Los Angeles, New York, and Columbia. The company's innovative approach combines machine learning with deep analytics, allowing content owners to seamlessly integrate brand placements within their media. Through its platform, Pandoodle aims to revolutionize brand messaging and elevate the monetization potential for media and content publishers.

CharlestonPharma

Seed Round in 2013
CharlestonPharma, LLC focuses on developing therapeutic products for cancer patients and healthcare providers. It is developing human monoclonal antibodies (mAbs) to the cell surface receptor, nucleolin. The company has worldwide license for the method of production of the mAbs and use of the anti-nucleolin antibodies to treat cancer patients. CharlestonPharma was incorporated in 2010 is based in Charleston, South Carolina.

Cirtemo

Series A in 2012
Cirtemo specializes in the development of advanced optical filter technology aimed at enhancing chemical detection capabilities. The company's innovative multivariate optical elements utilize microscopic sensors to provide increased sensitivity and specificity in analyte detection, surpassing the limitations of traditional narrow band pass filters. By partnering with Optical Filter Manufacturers and Optical Component and System Manufacturers, Cirtemo enables these partners to offer differentiated products while maintaining a strong intellectual property position. This collaboration empowers clients to address new applications in chemical measurement that were previously unattainable, ultimately improving detection limits and minimizing crosstalk in their analytical processes.

Proterra

Series B in 2012
Proterra Inc. designs and manufactures zero-emission electric buses, specializing in heavy-duty vehicles that enable fleet operators to reduce operating costs and eliminate fossil fuel dependency. The company’s product lineup includes 35-foot and 40-foot Catalyst transit vehicles, which are built to meet the diverse mileage needs of urban and regional routes on a single charge. Proterra also provides a range of services, including pre-delivery consultations, training programs, mid-life inspections, and battery management services. Their offerings extend to energy services such as fleet planning, charging infrastructure, and telematics. Founded in 2004 and headquartered in Burlingame, California, Proterra has additional offices in South Carolina and California, and its products are designed, engineered, and manufactured in the United States. By helping customers transition to battery-electric transit solutions, Proterra has contributed to significant reductions in greenhouse gas emissions and fuel consumption.

Kiyatec

Series A in 2012
Kiyatec, LLC specializes in developing advanced 3D cell-based assays aimed at enhancing preclinical drug discovery and clinical therapy applications. The company’s innovative 3DKUBE technology platform facilitates the creation of perfused 3D cell-based models that simulate complex human biology, allowing for more accurate predictions of drug toxicity and efficacy. Kiyatec conducts both standard and custom cell-based assays for biopharmaceutical clients, and it is involved in research initiatives funded by the National Cancer Institute, focusing on cancer types such as breast cancer, glioblastoma, and lung cancer. Its services include drug response profiling using patients' own living tumor cells, which help in identifying effective treatments. Additionally, Kiyatec provides tools for researchers and clinicians to advance the development of medical devices, therapeutic drugs, and tissue implants. Founded in 2005 and based in Greenville, South Carolina, Kiyatec aims to improve patient outcomes by facilitating more personalized approaches to cancer treatment.

Proterra

Series A in 2011
Proterra Inc. designs and manufactures zero-emission electric buses, specializing in heavy-duty vehicles that enable fleet operators to reduce operating costs and eliminate fossil fuel dependency. The company’s product lineup includes 35-foot and 40-foot Catalyst transit vehicles, which are built to meet the diverse mileage needs of urban and regional routes on a single charge. Proterra also provides a range of services, including pre-delivery consultations, training programs, mid-life inspections, and battery management services. Their offerings extend to energy services such as fleet planning, charging infrastructure, and telematics. Founded in 2004 and headquartered in Burlingame, California, Proterra has additional offices in South Carolina and California, and its products are designed, engineered, and manufactured in the United States. By helping customers transition to battery-electric transit solutions, Proterra has contributed to significant reductions in greenhouse gas emissions and fuel consumption.

Sabal Medical

Debt Financing in 2010
Sabal Medical is a healthcare platform that connects nurses and pharmacists together. Sabal Medical was founded in 2006 by William Park and David Duranceau and is based in Scranton. It was acquired by Swisslog in 2011.

Selah Technologies

Series A in 2008
Selah Technologies, LLC is an advanced materials manufacturing company developing and commercializing two proprietary nanotechnologies. Selah Dotsâ„¢ are patent-pending photoluminescent carbon-based nanoparticles. Selah Tubesâ„¢ are enriched single-walled nanotubes with precisely engineered electronic properties protected under US Patent No. 7,374,685. Our mission is to consistently deliver high quality nanomaterials and nano-enabled products to the global marketplace. Our growth strategy is to leverage relationships with market leading companies to establish mutually beneficial joint research and development agreements. Our strategy is founded in the conviction that early successes in our target markets will occur via exploitation of nanomaterials in established applications in which their incorporation is both useful and compelling, and addresses needs that nanotechnology can fulfill either immediately or in the very short term.
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