BoxOne Ventures

Spiderwort is a Canadian company based in Ottawa, founded in 2015, that specializes in developing biomaterials for regenerative medicine. The company focuses on creating plant-derived cellulose-based biomaterials, which are engineered to form various scaffold architectures. These innovative biomaterials aim to facilitate the repair and regeneration of tissues within the human body, including applications for spinal cord injury repair and soft tissue regeneration. Currently in the pre-clinical stage, Spiderwort's products show promising results in terms of biocompatibility and the ability to induce angiogenesis, which is the generation of new blood vessels within the scaffolds. By utilizing both biological and synthetic polymers, Spiderwort offers a range of product forms, including powders, gels, membranes, and pastes, contributing to advancements in healthcare and regenerative therapies.

Unravel Biosciences develops a vertically integrated computational platform to improve drug discovery. Unravel’s platform screens many drugs in parallel for their real-world impact (e.g., the complete gene expression profiles and resulting physiological changes), reversing this process to identify the likely target(s) a drug is interacting with.

DrugBank is a comprehensive online database that contains information on drugs and drug targets. They organize, collect, and curate all the important information about drugs into a single unified resource. It also combines detailed drug such as pharmacological, pharmaceutical, and chemical data with the comprehensive drug target sequence, structure, and pathway information. DrugBank is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students, and the general public. It was founded in 2015 and is headquartered in Edmonton, AB, USA.

Shakepay Inc. is a technology company based in Montreal, Canada, that offers financial applications aimed at helping users build wealth through digital currencies. Founded in 2015, Shakepay enables Canadians to buy and sell Bitcoin and facilitates peer-to-peer payments among users. Additionally, the company provides a VISA debit card that allows cardholders to load and spend Bitcoin for various transactions, including point of sale purchases, ATM withdrawals, and online orders. Through its mobile app, Shakepay aims to simplify the process of engaging with cryptocurrency for its users.

Coinmiles is the ultimate reward app that gives user cashback in cash or Bitcoin when they shop at our partner's locations.

Pathway is a health technology company focused on enhancing access to essential medical information for clinicians and patients during the care journey. The company develops a point-of-care reference tool that provides rapid access to evidence-based clinical guidelines. By organizing and condensing medical literature, Pathway aims to make critical information more accessible and easier to understand for healthcare professionals. This approach enables clinicians to work more efficiently, ultimately improving patient outcomes. Leveraging artificial intelligence and big data, Pathway creates a medical knowledge graph and software solutions that integrate evidence-based medicine into clinical practice.

Seqera Labs is a Barcelona-based business creating solutions for high-performance computing workloads across cloud and clusters. It was founded by the creators of the popular open-source workflow software Nextflow (http://www.nextflow.io).

Colabra specializes in enhancing the efficiency of scientific teams through its development of data integration and collaboration tools. The company provides a platform that facilitates real-time collaboration, allows for the integration of diverse data sources, and supports agile project management. This enables scientific researchers to effectively track their workflows, share data, and communicate outcomes. By streamlining these processes, Colabra aims to eliminate inefficiencies and boost research productivity, ultimately fostering a more innovative approach to scientific research and development.

Revelio Labs specializes in labor market analytics, providing detailed insights into the workforces of companies globally. The company utilizes advanced AI technologies to analyze vast amounts of online profiles, resumes, and job postings, transforming this data into actionable insights. Its platform standardizes public employment records to create a comprehensive HR database, which allows corporate strategists, HR professionals, venture capitalists, and investors to understand workforce dynamics, identify skill gaps, and uncover trends in human capital. By offering valuable workforce analytics, Revelio Labs enables clients to make informed, data-driven decisions in their strategic planning and workforce management.

Developer of neurological disorders therapy designed for critical mediators of inhibition within the brain. The company's platform has developed a proprietary neuron-specific K-Cl cotransporter (KCC2) discovery engine to improve the lives of people suffering from neurological disorders by fine-tuning inhibition to treat conditions such as epilepsy, pain, and other central nervous system pathologies, thereby enabling the healthcare industry to resist neurodegeneration, restore excitation, and regenerate neurons.

FabricNano Limited. manufactures supercharging biochemical cells to optimize chemical reaction speed, purity, and adaptability. The company was founded in 2018 and is based in London, United Kingdom.

Nvstr is a smarter, simpler, social online platform that empowers investors of all skill levels to enhance their profitability by 1) learning from other users' and experts' investment ideas and 2) improving how their ideas are translated into an intelligent portfolio. Their platform streamlines a common conversation topic - "What stocks do you like these days?" - by enabling users to browse friends' and experts' top ideas while preserving the privacy of their own portfolios and positions. Once a user finds investment ideas they like, an effortless, institutional-quality process assists in allocating the portfolio pursuant to their own specific investment objectives. The result is an investing experience that is simpler, more engaging, yet also substantially more sophisticated than that of traditional online brokerages.

Kenota Health develops next-generation rapid point-of-care system intended to be used for allergy testing in humans. Kenota's diagnostic tools are safe, simple, and offer a cheaper alternative to allergy testing using a thorough non-invasive technology, enabling physicians to improve patient outcomes.

Slingshot is a decentralized finance (DeFi) trading platform that facilitates the trading of crypto assets. Founded in 2018 and based in San Francisco, California, Slingshot helps users find the best prices for token trades and offers a mobile-friendly interface for seamless trading. The platform aggregates a wide variety of tokens, providing valuable insights that enhance the trading experience. By enabling clients to trade digital assets securely through their wallets, Slingshot aims to simplify and improve access to the growing crypto market. The company was previously known as DEXAG, Inc. before rebranding in November 2020.

Developer of a financial platform intended to trade options, futures, perpetual, and hedges all in one place. The company's platform offers crypto options and derivatives trading services on mobile, request for quote (RFQ), a powerful tool for traders to manage risk and obtain the prices for large and complex trades, enabling professional traders to optimize profits and reduce the risk of impermanent loss.

Injective Protocol Inc. is a company that develops and operates a decentralized derivatives exchange and trading platform. Founded in 2018 and based in New York, it offers a layer-2 exchange protocol designed to enhance borderless finance. The platform supports various trading options, including margin trading, derivatives, and futures, while also enabling decentralized lending and short or long margin trading. Notably, it features mechanisms to eliminate front-running, ensuring fair liquidity sharing among users.

DrugBank is a comprehensive online database that contains information on drugs and drug targets. They organize, collect, and curate all the important information about drugs into a single unified resource. It also combines detailed drug such as pharmacological, pharmaceutical, and chemical data with the comprehensive drug target sequence, structure, and pathway information. DrugBank is widely used by the drug industry, medicinal chemists, pharmacists, physicians, students, and the general public. It was founded in 2015 and is headquartered in Edmonton, AB, USA.

Sollum Technologies Inc. designs and manufactures lighting systems. Its lighting systems include LED hardware and programmable platform to provide the right light at various stages of crop growth; and a natural circadian rhythm to animals. The company was incorporated in 2015 and is based in Montreal, Canada.

Floating Point Group is a cryptocurrency firm based in New York City that specializes in smart-order-routing(SOR) technology. The system solves market illiquidity, allowing block trades that would normally be executed by OTC desks to be routed through cryptocurrency exchanges while intelligently avoid slippage- bolstering the markets and decreasing volatility. Similar to the evolution of the traditional financial markets, SOR systems are necessary for the successful maturation of cryptocurrency. Floating Point Group integrates technology for the digital currency markets into trading strategies through a single API. The platform is offering innovative, industry-leading trade execution and settlement. They help hedge funds, asset managers, and institutional investors adapt to rapidly evolving market structure with a platform of modular trading technology that lets them deploy customizable trading applications for order execution, market data, and trade settlement with just a couple lines of code.

Botpress, Inc. is a company that specializes in designing and developing an open-source chatbot development platform. Founded in 2016 and based in Newark, Delaware, Botpress provides software that enables the creation of various types of chatbots, including scripted, artificial intelligence, and application-based options. The platform is widely used by developers, organizations, and individuals, facilitating the building, deployment, and management of chatbots. Key features include a conversational flow management system and natural language understanding, allowing businesses to create customizable conversational experiences. Additionally, the platform is designed to be manageable by non-developers after deployment, making it accessible for a broader audience to enhance their conversational strategies.

Nvstr is a smarter, simpler, social online platform that empowers investors of all skill levels to enhance their profitability by 1) learning from other users' and experts' investment ideas and 2) improving how their ideas are translated into an intelligent portfolio. Their platform streamlines a common conversation topic - "What stocks do you like these days?" - by enabling users to browse friends' and experts' top ideas while preserving the privacy of their own portfolios and positions. Once a user finds investment ideas they like, an effortless, institutional-quality process assists in allocating the portfolio pursuant to their own specific investment objectives. The result is an investing experience that is simpler, more engaging, yet also substantially more sophisticated than that of traditional online brokerages.

ORA is a Montreal-based startup working with advanced nano-materials to produce unparalleled audio experiences. Their team of sound engineers, chemists and material scientists work with the exciting properties of *Graphene* (the strongest and lightest material known to man) to deliver smaller/lighter, more energy efficient speakers, all while remarkably improving sound quality. With a simple drop-in replacement of the speaker’s membrane, GrapheneQ can 1) extend the battery life of a portable audio device by up to 70% b) generate up to 4x the volume and c) significantly reduce the overall size of the speaker, allowing for bigger batteries/thinner devices. ORA's technology is disrupting a technology that has seen little innovation since its invention in 1921: the loudspeaker!

Wallit, Inc. operates as a rewards-based financial wellness platform and savings app tailored for families with teenagers. Founded in 2016 and based in Westbrook, Maine, the platform allows users to link their checking and savings accounts, providing a comprehensive view of their financial status. Wallit incentivizes savings and responsible spending by rewarding users for achieving specific financial goals, such as completing chores or maintaining good academic performance. The application is designed to facilitate money transfers from parents to teens, thereby addressing common financial challenges within families. Wallit partners with banks, credit unions, and other financial institutions to enhance its offerings, promoting a responsible approach to cashback through automated savings and real-time budgeting tools.

StreamingFast, formerly known as dfuse Platform Inc., specializes in developing blockchain applications and solutions that facilitate the creation of efficient, decentralized applications. Founded in 2013 and based in Montreal, Canada, the company offers a suite of robust APIs designed to help developers organize and access decentralized data. Key products include dfuse Stream, dfuse Lifecycle, dfuse Search, and dfuse On Demand Networks, which collectively enable real-time state updates, rapid searches, and reliable transaction guarantees. Through its low-latency architecture, StreamingFast empowers developers to create superior user experiences and supports the ongoing evolution of the blockchain ecosystem.

Developer of a health technology company delivering precision datasets from the gastrointestinal tract leveraging a capsule sampling technology and creating a paradigm shift in how GI health is diagnosed and treated. The company's product enables passive sampling of small bowel luminal fluid to leverage intestinal data to provide insights, enabling healthcare providers with direct sampling and analysis of targeted regions of the gastrointestinal tract.

Sollum Technologies Inc. designs and manufactures lighting systems. Its lighting systems include LED hardware and programmable platform to provide the right light at various stages of crop growth; and a natural circadian rhythm to animals. The company was incorporated in 2015 and is based in Montreal, Canada.