Bioventus
Bioventus LLC is a medical technology company specializing in orthobiologic solutions aimed at enhancing bone healing and managing osteoarthritis. The company offers a range of products, including active healing therapies that support the recovery of bone fractures and alleviate chronic pain associated with osteoarthritis. Its portfolio features injection therapies for osteoarthritic joints, surgical orthobiologics, and bone healing solutions that promote the body’s natural healing processes. Key offerings include the EXOGEN Ultrasound Bone Healing System and various joint fluid therapies. Bioventus is recognized for its innovative and effective products, which adhere to high quality standards and evidence-based practices. Headquartered in Durham, North Carolina, Bioventus employs around 500 people and generates approximately $240 million in annual revenue. The company operates a distribution network to make its products available to healthcare providers. Bioventus was established in 2011, evolving from the Biologics Division of Smith & Nephew.
Trice Medical, Inc. specializes in developing orthopedic diagnostic devices that incorporate camera-enabled technologies and needle-based systems. Founded in 2011 and based in Malvern, Pennsylvania, the company aims to enhance orthopedic diagnostics by providing instant and accurate visual insights for patients, physicians, and payors. Trice Medical's innovative products facilitate minimally invasive procedures that can be performed in an office setting, offering painless and cosmetically undetectable solutions for both diagnostic and therapeutic purposes. The company's technology addresses the shortcomings of traditional diagnostic methods, significantly reducing false readings and overall healthcare costs, while optimizing the delivery of patient care.
Misonix has long been at the forefront of ultrasound technology and is a world leader in the design, development, manufacturing, and marketing of ultrasonic surgical devices. Their innovative, ultrasonic platforms for surgical applications include aspirators for the removal of both soft and hard tissue, instruments for laparoscopic cutting and coagulation, devices for wound cleansing and debridement, products for precision bone cutting and sculpting, liposuction instrumentation for improving body aesthetics, and High Intensity Focused Ultrasound (HIFU) systems for the ablation of tumors.
Vaporox, Inc. specializes in developing a therapeutic delivery system aimed at treating various skin wounds. The company's core offering, Vaporous Hyperoxia Therapy (VHT), utilizes low-frequency ultrasonic waves to create anti-microbial particles that are delivered non-contact and non-thermally to the wound bed. This innovative approach is designed to address a range of conditions, including diabetic foot ulcers, burns, frostbite, gangrene, pressure ulcers, and skin grafts. Founded in 2016 and headquartered in Denver, Colorado, Vaporox aims to establish VHT as the preferred treatment for diabetic foot ulcers while exploring opportunities to extend its technology to other skin ailments or license it to medical device companies. The company was previously known as Wound Care, Inc. before rebranding in January 2019.
Bioness Inc. designs, develops, and distributes medical devices for people with stroke, multiple sclerosis, traumatic brain injury, cerebral palsy, and spinal cord injury. It offers L300, a foot drop system for people with various neurological conditions; L300 Plus for foot drop and thigh weakness, which delivers programmed, low-level electrical stimulation to activate the nerves controlling the muscles of the leg; H200, a wireless hand rehabilitation system for reaching, grasping, opening, and closing the hand; and StimRouter, an implantable neuromodulation device designed to treat intractable pain of peripheral nerve origin. The company also offers StimRouter, an implantable neuromodulation device to treat chronic intractable pain of peripheral nerve origin as an adjunct to other modes of therapy. Bioness Inc. was founded in 2004 and is based in Valencia, California.
Cartiheal Ltd., a medical device company, develops implants for the regeneration of cartilage and bone disorders. The company offers Agili-C, an off the shelf and cell-free implant that regenerates hyaline cartilage and its underlying subchondral bone. Its implant is used for the treatment of focal articular cartilage and osteochondral defects. The company was founded in 2009 and is based in Kfar Sava, Israel.
Cartiheal Ltd., a medical device company, develops implants for the regeneration of cartilage and bone disorders. The company offers Agili-C, an off the shelf and cell-free implant that regenerates hyaline cartilage and its underlying subchondral bone. Its implant is used for the treatment of focal articular cartilage and osteochondral defects. The company was founded in 2009 and is based in Kfar Sava, Israel.
BioStructures, LLC is a medical device company based in Newport Beach, California, specializing in bioresorbable bone graft products for spinal surgical applications. Founded in 2009 by Russell Cook, the company develops and commercializes a range of synthetic and allograft implants aimed at enhancing bone regeneration and remodeling for various clinical procedures. Its product portfolio includes offerings such as Signafuse bioactive bone graft putty, Interface bioactive bone graft, Osteomatrix mineralized collagen scaffold, Osteoplus bone graft composite, Exponent demineralized bone matrix, Purebone demineralized cancellous tissue, Extractor bone marrow aspiration needle, and Prohesion hydrolyzed surgical powder. As of late 2015, BioStructures operates as a subsidiary of Bioventus LLC.
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