PPD

Science 37, Inc. is a technology-driven clinical trial company focused on transforming clinical research through patient-centric models. It has developed NORA (Network Oriented Research Assistant), a cloud-based mobile research platform that facilitates communication between researchers and patients via videos, photographs, and surveys, enabling end-to-end networked clinical trial services. The company also offers the Science 37 Metasite, which enhances access to diverse patient populations for clinical studies, and the Science 37 Platform for decentralized clinical trials. By utilizing its virtual model, Science 37 has demonstrated faster enrollment and higher patient retention, reaching a broader and more representative patient demographic than traditional site-based research. The company serves a wide range of clients, including large pharmaceutical firms, biotechnology companies, universities, and startups. Since its incorporation in 2014, Science 37 has established itself as a leader in virtual clinical trials, leveraging an extensive network of telemedicine investigators and home-health nurses to conduct more decentralized interventional trials than any other organization.

Medable, Inc. operates a cloud-based platform that facilitates decentralized clinical trials, enabling healthcare providers, biopharma sponsors, and clinical research organizations to enhance trial design, recruitment, retention, and data quality. The platform integrates various digital tools and services, ensuring compliance with health regulations while improving patient access and experience. Key offerings include solutions for telemedicine, such as HIPAA-compliant video consultations and platforms for capturing clinical trial outcomes remotely. Medable's services support the creation of applications for mobile, desktop, and web use, addressing the needs of doctors, hospitals, and health technology companies. Founded in 2015 and headquartered in Palo Alto, California, Medable has been utilized in clinical trials across over 30 countries and 26 languages, contributing to more effective therapy delivery and patient outcomes.

Medable, Inc. operates a cloud-based platform that facilitates decentralized clinical trials, enabling healthcare providers, biopharma sponsors, and clinical research organizations to enhance trial design, recruitment, retention, and data quality. The platform integrates various digital tools and services, ensuring compliance with health regulations while improving patient access and experience. Key offerings include solutions for telemedicine, such as HIPAA-compliant video consultations and platforms for capturing clinical trial outcomes remotely. Medable's services support the creation of applications for mobile, desktop, and web use, addressing the needs of doctors, hospitals, and health technology companies. Founded in 2015 and headquartered in Palo Alto, California, Medable has been utilized in clinical trials across over 30 countries and 26 languages, contributing to more effective therapy delivery and patient outcomes.

Science 37, Inc. is a technology-driven clinical trial company focused on transforming clinical research through patient-centric models. It has developed NORA (Network Oriented Research Assistant), a cloud-based mobile research platform that facilitates communication between researchers and patients via videos, photographs, and surveys, enabling end-to-end networked clinical trial services. The company also offers the Science 37 Metasite, which enhances access to diverse patient populations for clinical studies, and the Science 37 Platform for decentralized clinical trials. By utilizing its virtual model, Science 37 has demonstrated faster enrollment and higher patient retention, reaching a broader and more representative patient demographic than traditional site-based research. The company serves a wide range of clients, including large pharmaceutical firms, biotechnology companies, universities, and startups. Since its incorporation in 2014, Science 37 has established itself as a leader in virtual clinical trials, leveraging an extensive network of telemedicine investigators and home-health nurses to conduct more decentralized interventional trials than any other organization.

Medable, Inc. operates a cloud-based platform that facilitates decentralized clinical trials, enabling healthcare providers, biopharma sponsors, and clinical research organizations to enhance trial design, recruitment, retention, and data quality. The platform integrates various digital tools and services, ensuring compliance with health regulations while improving patient access and experience. Key offerings include solutions for telemedicine, such as HIPAA-compliant video consultations and platforms for capturing clinical trial outcomes remotely. Medable's services support the creation of applications for mobile, desktop, and web use, addressing the needs of doctors, hospitals, and health technology companies. Founded in 2015 and headquartered in Palo Alto, California, Medable has been utilized in clinical trials across over 30 countries and 26 languages, contributing to more effective therapy delivery and patient outcomes.

Science 37, Inc. is a technology-driven clinical trial company focused on transforming clinical research through patient-centric models. It has developed NORA (Network Oriented Research Assistant), a cloud-based mobile research platform that facilitates communication between researchers and patients via videos, photographs, and surveys, enabling end-to-end networked clinical trial services. The company also offers the Science 37 Metasite, which enhances access to diverse patient populations for clinical studies, and the Science 37 Platform for decentralized clinical trials. By utilizing its virtual model, Science 37 has demonstrated faster enrollment and higher patient retention, reaching a broader and more representative patient demographic than traditional site-based research. The company serves a wide range of clients, including large pharmaceutical firms, biotechnology companies, universities, and startups. Since its incorporation in 2014, Science 37 has established itself as a leader in virtual clinical trials, leveraging an extensive network of telemedicine investigators and home-health nurses to conduct more decentralized interventional trials than any other organization.

Evidera specializes in health economics, outcomes research, and market access services, catering to life sciences organizations globally. The company focuses on optimizing patient access by providing evidence of the value, effectiveness, and safety of healthcare products. Its comprehensive offerings include evidence planning, strategic consulting, literature review, data analytics, health economics, modeling, and outcomes research. Evidera collaborates with a diverse clientele, from small biotechnology firms to large biopharmaceutical manufacturers, utilizing its deep understanding of the global payer and regulatory landscape to develop and communicate essential clinical and economic evidence. This commitment to high-quality research and consulting helps clients enhance the market access and commercial success of their products.

Synexus is a site network organization that continues to pioneer important developments in the clinical trials industry. Through a global network of 26 dedicated research centres (DRCs) in nine countries, Synexus provides first-class clinical trials data to its clients from pharma, biotechs and CROs. Synexus recruits patients and runs clinical trials at its own dedicated research centres staffed by full-time GCP investigators who work solely on clinical trials. It also expertise in trial planning, spanning patient recruitment, patient retention, and management. Synexus was founded in 1992 and is headquartered in Chorley, UK,

X-Chem, Inc. is a privately held biotechnology company located in Waltham, Massachusetts, founded in 2009. The company specializes in discovering small molecule leads for high-value therapeutic targets, utilizing its innovative DNA-Encoded Library (DEL) technology. This approach allows X-Chem to provide drug discovery services through the iterative combinatorial synthesis of small molecules, which are linked to DNA tags that document their synthetic history. By focusing on the generation of novel small molecule therapeutics, X-Chem aims to advance healthcare through its cutting-edge biotechnological services.

RCT Logic LLC develops and licenses clinical trial designs for use in trials sponsored by industry, non-profit entities, and governments in the United States. Its products include sequential parallel comparison design (SPCD), a clinical trial design that reduces the detrimental impact of placebo response and addresses the placebo response problem by utilizing placebo non-responders; and SPCD comparative analysis software calculator that allows a sponsor of a trial to calculate the design parameters for an SPCD trial under sponsor-provided specifications, and to analyze and understand the efficiency of SPCD in comparison to a conventional trial. The company was founded in 2007

BioDuro is a US-based, fully-integrated, end-to-end global life science outsourcing services company with a team of over 630 in Beijing, China. Their priority is providing the highest quality, FDA-compliant services at an affordable cost. Their clients are over 40 pharmaceutical and biotechnology companies, and their services span the entire range of drug discovery and development, from discovery chemistry, through pharmacology and drug safety and evaluation, to clinical trials. Today, BioDuro is working with 10 of the 12 largest pharmaceutical companies in the world.

Auven Therapeutics Management L.L.L.P formerly known as Celtic Therapeutics Holdings L.P. is a private equity firm specializing in acquiring and investing in proprietary therapeutic product candidates (small-molecules and biologics), drug development, and complementary technologies. The firm also invests in developing mid-stage pharmaceutical programs. It acquires ownership of clinical-stage therapeutic assets and potential new products, primarily mid-stage development programs, with all their associated intellectual property and proprietary preclinical and clinical data. Auven Therapeutics Management L.L.L.P was founded in 2007 and is based in Saint Thomas, Virgin Islands, with additional offices in Ft. Lauderdale, Bermuda, Florida and Lausanne, Switzerland.

Excel PharmaStudies Inc. (依格斯医疗科技有限公司) is a company focused on clinical research and contract research. It maintains close contact with government departments, industries, hospitals, and research institutes. PharmaStudies has conducted 123 clinical research projects from I to IV period in about 130 hospitals of 40 cities with the invovlment of 25,000 patients. It was founded in 1999, and is one of the earliest clinical research & contract research organizations in China.

AbCRO is a clinical research organization, provides clinical trial services to pharmaceutical and biotechnology companies in Southeastern Europe. It offers regulatory compliance, clinical monitoring, investigator recruitment, and project management services. The company was founded in 2000 and is based in Stamford, Connecticut. It was acquired in April 2009 by PPD.

Magen BioSciences is a Biotechnology company located in 100 Beaver Street, Suite 101, Waltham, MA, United States.