PMV Pharmaceuticals

PMV Pharmaceuticals, Inc. is a precision oncology company focused on the discovery and development of small molecule therapies targeting p53 mutations in cancer. Its lead candidate, PC14586, aims to correct and restore the function of the p53 protein, which is critical in regulating cell growth and preventing tumor formation. In addition to PC14586, the company is developing therapies for various p53 hotspot mutations, including the R273H mutation. Founded in 2013 and headquartered in Cranbury, New Jersey, PMV Pharmaceuticals leverages extensive expertise in p53 biology to advance its innovative treatment options for cancer patients.

Michael Carulli

CFO

2 past transactions

Apitope

Series B in 2015
Apitope is a biotechnology company dedicated to discovering and developing disease-modifying therapies for autoimmune and allergic diseases. Its research primarily targets conditions such as multiple sclerosis, Graves’ disease, Factor VIII intolerance, and uveitis. Utilizing a proprietary platform technology, Apitope develops antigen-specific therapeutic peptides aimed at addressing the underlying causes of these diseases. The company’s innovative approach seeks to enhance patients' quality of life by providing treatments that minimize the risk of secondary infections and complications. Apitope's first product candidate has been licensed to a major pharmaceutical partner, Merck Serono, while the company continues to advance its remaining portfolio of therapeutic candidates.

FF Pharma

Series A in 2013
FF Pharma is a biopharmaceutical company focused on developing innovative therapies for chronic inflammatory diseases, specifically targeting conditions such as primary biliary cirrhosis and Crohn’s disease. The company is advancing an anti-CD40 monoclonal antibody therapy that acts as a negative allosteric modulator of the CD40 pathway. This therapy serves as a reversible switch for B cell activation, inhibiting aberrant immune responses associated with autoimmune diseases. By targeting the CD40 pathway, FF Pharma aims to provide effective treatment options for patients suffering from chronic inflammation and related disorders.
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