Pivotal bioVenture Partners

Pivotal bioVenture Partners, established in 2016, is a San Francisco-based venture capital firm focusing on early-stage investments in biotechnology companies. With a $300 million fund, they invest in privately held North American and European companies developing innovative therapeutic products and platforms to address significant unmet medical needs. Their investment strategy spans from company creation through mid and late-stage clinical development. The firm's team, with diverse experience in venture capital, company building, and drug discovery and development, works closely with entrepreneurs to advance their businesses.

Meng Gao

Managing Partner

Rob Hopfner

Managing Director and Partner

Ashish Khanna Ph.D

Partner

Ash Khanna

Partner, Board Member HotSpot Tx, Bolt Bio, Fountain Tx and Evommune

Jeni Lee

Partner

Simon Tsang

Operating Partner

Robert Hopfner Ph.D

Managing Director

Past deals in Cayman Islands

Stealth BioTherapeutics

Convertible Note in 2018
Stealth BioTherapeutics is a clinical-stage biotechnology company dedicated to the discovery, development, and commercialization of therapies targeting diseases linked to mitochondrial dysfunction. Founded in 2006 and based in George Town, Cayman Islands, the company is advancing its lead product candidate, Elamipretide, which aims to address both rare genetic and age-related mitochondrial diseases. Additionally, Stealth BioTherapeutics is developing SBT-20, a small peptide that stabilizes mitochondrial structure and function during oxidative stress, and SBT-272, a compound under evaluation for rare neurodegenerative diseases, including amyotrophic lateral sclerosis. Mitochondria play a crucial role in energy production and overall organ function, making the company's focus on these organelles significant in the biopharmaceutical landscape.
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