Replay is a genome writing company focused on advancing genomic medicine by reprogramming biology through the writing and delivery of large DNA sequences. The company has developed a hypoimmunogenic induced pluripotent stem cell (iPSC) therapeutic platform, which aims to enhance the effectiveness of gene therapy and genome editing. By leveraging innovative technologies, Replay seeks to redefine the landscape of genetic treatments and improve patient outcomes in various therapeutic areas.
1859, Inc. is a biotechnology company that specializes in the discovery and development of next-generation therapeutics. Founded in 2019, the company is headquartered in San Diego, California. Its focus on innovative healthcare solutions positions it within the evolving landscape of biotechnology, where it aims to contribute to advancements in treatment options.
Mythic Therapeutics is a biotechnology company focused on a new generation of groundbreaking cancer therapeutics. The company is pioneering a powerful protein engineering-focused approach to improving the effectiveness of antibody-drug conjugates (ADCs) and other antibody-based therapeutics. Their technology dramatically increases therapeutic potency without compromising safety, thereby unlocking the full potential of targeted therapies against a broad array of tumor targets. Mythic Therapeutics was founded in 2017 and is headquartered in Waltham, MA, USA.
Developer of clinical-stage neuroscience therapeutics intended to harness novel neuroplasticity-promoting treatments for difficult-to-treat neuropsychiatric and neurological disorders. The company's compounds include non-hallucinogenic, non-psychotomimetic, and non-dissociative versions of psychedelic components, enabling healthcare service providers to address significant mental health challenges through phenotypic drug discovery across various chemotypes and mechanisms of action.
Developer of clinical-stage neuroscience therapeutics intended to harness novel neuroplasticity-promoting treatments for difficult-to-treat neuropsychiatric and neurological disorders. The company's compounds include non-hallucinogenic, non-psychotomimetic, and non-dissociative versions of psychedelic components, enabling healthcare service providers to address significant mental health challenges through phenotypic drug discovery across various chemotypes and mechanisms of action.
Operator of a biotechnology platform intended to increase binding affinity and improve consistency to help create personalized, precision cancer vaccines for patients of all backgrounds. The company's platform focuses on developing a single-molecule, massively parallel, de novo next-generation protein sequencing platform, enabling scientists and researchers to develop novel therapeutics and diagnostics and ultimately understand human biology and disease.
Sestina Bio, LLC is a biotechnology company founded in 2020 and based in Delaware. Formerly known as F-SynBio, the company focuses on developing a technology-centric research and development platform aimed at addressing significant global challenges. Sestina Bio seeks to provide innovative solutions to sustainably feed, clothe, and maintain the health of the growing world population. The company integrates cutting-edge advancements in synthetic biology, data sciences, and bio-analytical systems to achieve its mission.
Finch Therapeutics is a mission-driven microbiome engineering company, is developing novel microbial therapies to serve patients with serious and unmet medical needs.
The company uses machine learning algorithms to reverse engineer successful fecal transplantations and other clinical datasets, identifying the microbes that drive responses in patients. This human-centric discovery model leverages clinical data to focus on in-vitro and in-vivo efforts on cocktails of microbes that have already demonstrated safety and efficacy in humans. This enables early retirement of translational risk and avoids the challenges of extrapolating host-specific effects from animal models.
Finch Therapeutics was founded in 2017 and is headquartered in Somerville, Massachusetts.
Developer of clinical-stage neuroscience therapeutics intended to harness novel neuroplasticity-promoting treatments for difficult-to-treat neuropsychiatric and neurological disorders. The company's compounds include non-hallucinogenic, non-psychotomimetic, and non-dissociative versions of psychedelic components, enabling healthcare service providers to address significant mental health challenges through phenotypic drug discovery across various chemotypes and mechanisms of action.
TARA Biosystems, Inc. is a biotechnology company focused on developing organ-on-a-chip technology, specifically human cardiac tissue models, to enhance drug discovery and safety assessments. Founded in 2014 and based in the United States, the company utilizes stem cell-derived cardiac tissue that mimics adult physiological conditions, enabling precise measurement of cardiac functionality. This innovative platform aims to facilitate the faster and safer development of new therapies by providing predictive in vitro models that can assess the effects of drug compounds on heart function without the need for human testing. Through its advanced technology, TARA Biosystems seeks to improve the health of patients by enabling more reliable assessments of cardiac drug efficacy and safety.
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