MassVentures is a venture capital firm based in Waltham, Massachusetts, established in 1978 as a quasi-public corporation by the Massachusetts Legislature. The firm focuses on providing seed and early-stage funding to high-growth startups, facilitating their transition from concept to commercialization. MassVentures invests primarily in sectors such as information technology, healthcare, cybersecurity, e-commerce, mobile, manufacturing, and robotics. With a governance structure that includes an independent Board of Directors and management by experienced venture capitalists, MassVentures leverages the state's entrepreneurial spirit and innovation centers to support the Massachusetts innovation economy. The firm also offers accelerator programs to further assist emerging companies in their growth journey.

Founded in Boston in 2004, RA Capital is an investment firm specializing in life sciences and drug development. Its team, with backgrounds in biology, chemistry, medicine, and industry experience, invests in early-stage companies with promising technologies and products across healthcare and life science sectors.

Polaris Partners is a venture capital firm based in Boston, Massachusetts, with offices in San Francisco. Founded in 1996, it targets investments in technology and life science companies across the United States and Europe, supporting startups from early formation to profitable growth. The firm's healthcare and biotechnology focus encompasses digital health, consumer-centric care delivery, patient-provider solutions, data science and analytics, as well as therapeutics, genomics and other life science platforms. It backs companies across business-to-business and business-to-consumer models, software as a service, healthcare information technology and health tech sectors, partnering with repeat entrepreneurs to build durable, scale-ready businesses.

Atlas Venture is an early-stage venture capital firm based in Cambridge, Massachusetts, specializing in life sciences and biotechnology. It supports the translation of high-impact scientific discoveries into medicines for patients through a seed-led venture creation strategy that identifies and builds scalable companies with strong scientific foundations. The firm combines experienced scientists and career venture capitalists to select compelling opportunities and realize value, emphasizing early-stage investments in life sciences and technology. Atlas Venture also maintains a multi-disciplinary team able to advance startups from concept to clinical development and commercial viability.

Founded in 2000, General Catalyst is a venture capital firm specializing in early-stage and growth equity investments. It focuses on accelerating ideas, careers, and companies towards success by providing ongoing momentum and mentorship based on deep experience.

Alumni Ventures Group is a venture capital firm based in Manchester, New Hampshire, with offices across North America. It provides access to venture investing for individual accredited investors, particularly alumni networks, by offering diversified portfolios of venture opportunities and allowing members to invest alongside fellow alumni in ventures led by peers. The firm backs early-stage and later-stage opportunities across technology, consumer, healthcare, financial services, and other sectors, with a sector- and geography-agnostic approach. It typically invests between $10,000 and $3 million per deal and emphasizes the involvement of alumni connections and an institutional lead investor in opportunities. Alumni Ventures also offers focused funds to broaden participation, enabling accredited investors to access venture portfolios diversified by type, sector, stage, and geography. The model aims to democratize access to venture capital while maintaining rigorous selection standards through alumni networks.

Founder Collective is a venture capital firm founded in 2009 and headquartered in Cambridge, Massachusetts, with an office in New York. It focuses on seed- and early-stage technology companies, investing primarily in software, information technology, and TMT sectors across the United States and globally. The firm was established by successful entrepreneurs who have built and exited companies, and it emphasizes a founder-friendly approach that aims to minimize capital requirements while supporting portfolio companies. Although industry-agnostic, Founder Collective prefers opportunities with an information technology component and pursues a hands-on, founder-oriented investment style through multiple co-managed funds.

Founded in 1986, Morningside Group is a venture capital firm based in the greater Boston area. It invests in companies with innovative science and technology across life sciences, digital health, AI, materials, and technology sectors.

New Enterprise Associates is a venture capital firm founded in 1977 and based in Menlo Park, California, with offices in the United States, India and China. It makes investments across technology and healthcare startups at multiple stages, from seed to growth, including software, cloud, data, internet services, fintech, AI, e-commerce, and enterprise technology, as well as healthcare information technology, life sciences, medical devices, and biopharma. It also considers energy technology and infrastructure opportunities, such as solar, batteries and smart grids. The firm pursues a global approach, with activity in the United States, Asia and other regions, and supports companies through rounds of financing ranging from small to sizable investments as they scale. NEA focuses on building portfolios in software, IT services, consumer technology, and healthcare technology, backing ambitious entrepreneurs across sectors and geographies.

Founded in 1986, ARCH Venture Partners is a venture capital firm specializing in investments that bring innovations in life sciences to market. It focuses on companies co-founded by scientists and entrepreneurs, with a strong track record in commercializing technologies from academic research institutions and national laboratories.

Accomplice is a Boston-based venture capital firm, with an additional office in San Francisco, specializing in seed and early-stage investments in technology startups. It primarily invests in companies focused on cybersecurity, eSports, data analytics, SMB class software, emerging hardware platforms, and marketplaces. Accomplice uniquely leverages community platforms like AngelList, Boston Syndicates, and Maiden Lane to empower and fund exceptional founders. With a majority of its investments in Boston and additional investments throughout the U.S., Canada, and the E.U., Accomplice is one of the most active early-stage firms in New England.

Flagship Pioneering is a Cambridge, Massachusetts-based venture creation firm that conceives, creates, resources, and grows first-in-category companies across health technology, biotechnology, medicine, engineering, energy, and related fields. The organization aims to transform human health and sustainability by turning seemingly unreasonable ideas into transformational ventures through an evolutionary, science-driven approach. It combines inventive capacity, entrepreneurial leadership, and capital management within a single enterprise to systematically build new companies that pursue breakthrough advances in biology, engineering, and medicine. Since its founding in 2000, Flagship Pioneering has developed and nurtured a portfolio of ventures by integrating scientific discovery with disciplined entrepreneurship, seeking to accelerate innovations from concept to market.

Mission BioCapital is a life science venture capital firm investing in early-stage companies within the biotechnology sector. Founded in Cambridge, Massachusetts in 2009, the company is known for its experienced leadership team and deep support provided to portfolio companies.

Alexandria Venture Investments is the strategic venture capital arm of Alexandria Real Estate Equities. Based in Pasadena, California, it provides long-term strategic capital to innovative life sciences and technology companies developing breakthrough therapies, diagnostics, and platforms across biopharma, digital health, agrifoodtech, agtech, and related healthcare fields. Established in 1996, the firm invests across seed, early, and growth stages and leverages its deep industry knowledge, extensive investor networks, and scientific advisory resources to support portfolio companies. The unit also pursues opportunities at the intersection of real estate, life sciences, and technology, reflecting its parent company's sector focus and integrated ecosystem approach. It aims to help entities advance human health by partnering with founders to scale transformative technologies.

Spark Capital is a venture capital firm founded in 2005 and based in San Francisco with offices in Boston and New York. It invests in startups across the United States, spanning early-stage to growth opportunities, focusing on software, internet, media, consumer products and services, fintech, and information technology. The firm backs companies across sectors such as software-as-a-service, digital media, online platforms, and technology-driven consumer products, often supporting ventures at the intersection of entertainment and technology, e-commerce, and education technology. It typically makes investments from formative rounds up to larger growth rounds, and seeks to take a board seat in portfolio companies to help guide strategy and growth. Notable investments include Twitter, Discord, Anthropic, Cruise, Niantic, Oculus, Warby Parker, and Tumblr, illustrating a history of backing influential products and teams.

Casdin Capital is a New York‑based investment firm founded in 2012 by Eli Casdin. The firm specializes in fundamental research and long‑short equity strategies focused on the life sciences and healthcare sectors, including oncology, digital health, and agtech. In addition to its public‑market fund, Casdin Capital invests in early‑stage to late‑stage private companies within these industries. It operates as a Registered Investment Adviser and, as of October 2020, managed approximately $2.2 billion in assets.

Founded in 1989, OrbiMed is a New York-based healthcare-dedicated investment firm managing approximately $5 billion in assets. It invests across the spectrum of healthcare companies, from private start-ups to large multinational corporations, focusing on biopharmaceuticals, life sciences, digital health, medical devices, and diagnostics sectors globally.

Insight Partners is a global private equity and venture capital firm founded in 1995 that acts as a software investor, partnering with growth-stage technology and software companies. The firm concentrates on Fintech, Cybersecurity, AI/ML, DevOps, and Healthcare, providing capital and hands-on support to help management teams scale. Headquartered in New York City with offices in London, Tel Aviv, and Palo Alto, Insight Partners has more than $75 billion in assets under management, has invested in over 750 companies worldwide, and more than 55 portfolio companies have reached an IPO.

F-Prime Capital is a venture capital firm based in Cambridge, Massachusetts, affiliated with Fidelity Investments. It backs technology and life sciences entrepreneurs across the Americas, Europe, and Asia, drawing on Fidelity’s experience in funding early-stage companies. The firm focuses on sectors such as healthcare IT, medtech, therapeutics, fintech, frontier technologies, crypto, and broader information technology and technology-enabled services. With a global network of regional teams and affiliated funds, F-Prime provides domain expertise, strategic guidance, and industry connections to help founders build durable companies. It operates with a long-term, founder-centric approach, emphasizing value creation rather than external fundraising pressures.

Matrix is a San Francisco based venture capital firm founded in 1977 that backs early-stage companies across AI, B2B, consumer, fintech, health tech, and infrastructure. It works with product teams from idea through Series A, offering hands-on support and strategic guidance to help portfolio companies reach scale. The team comprises former founders and operators who bring practical insight to building startups. Matrix operates globally, including Matrix Partners China, which builds long-term relationships with entrepreneurs in China and abroad and invests across sectors and stages. Over its history, Matrix has backed companies that progressed to IPOs or acquisitions, reflecting a focus on durable growth and long-term value creation through close founder collaboration and a global network.

Boston-based venture capital firm founded in 2005 that focuses on early-stage and select growth investments in information technology and related services. The firm backs enterprise IT companies, emphasizing information security, cloud infrastructure, data analytics, and software-as-a-service models, as well as technology-enabled business services and digital health, and it also targets healthcare IT, fintech, mobile software, and next-generation software. It prefers open source and SaaS delivery. Typically investing initial rounds of 2 to 5 million and totaling 6 to 10 million per company, it seeks board representation and often serves as lead or first institutional investor, with minority to majority stakes ranging from 20 to 80 percent. The firm reserves capital for opportunistic investments in more mature companies where its team has prior experience and focuses on opportunities in the Northeast United States.

Khosla Ventures is a California-based venture capital firm founded in 2004 by Vinod Khosla. It provides capital and strategic guidance to startups across stages, focusing on technology-driven companies in areas such as artificial intelligence, climate and sustainability, enterprise software and services, fintech, digital health, medical technology and diagnostics, therapeutics, consumer products, and frontier technologies. The firm backs bold ventures with the potential to disrupt markets and improve lives, supporting companies from early to growth stages and working closely with entrepreneurs to apply science, technology and innovative business models. While primarily investing in North American technology companies, Khosla Ventures pursues opportunities globally and emphasizes experimentation and impact alongside financial returns. The firm also maintains related impact initiatives that support entrepreneurs addressing socio-economic challenges in emerging markets.

SV Health Investors is a venture capital and growth equity firm focused on healthcare and life sciences. Headquartered in the United States with offices in Boston, San Francisco and London, the firm supports entrepreneurs who develop breakthrough medicines, devices and related technologies. It manages multiple private healthcare funds and has a 20-year track record in the US and Europe, investing across North America and Western Europe to advance innovative treatments and diagnostics. SV Health Investors aims to transform healthcare by backing early-stage and growth opportunities in biotechnology, medical devices and related sectors.

Pillar VC is a Boston-based venture capital firm established in 2016 that provides early capital and supports founders from inception through growth. It backs university spinouts led by first-time founders as well as serial entrepreneurs, aiming to build meaningful, scalable companies. The firm focuses on high-potential ventures across machine intelligence, AI, hardware, enterprise software, blockchain, quantum, digital health, and synthetic biology, and offers connections, coaching, and a community to help founders develop personally and professionally. Pillar VC is open to ventures of various types and emphasizes hands-on support and collaboration to accelerate progress.

Eli Lilly and Company is a global pharmaceutical leader engaged in the discovery, development, manufacture, and sale of medicines. It operates facilities in the United States, Puerto Rico, and many other countries, with products sold in about 135 countries. The company focuses on therapies in neuroscience, cardiometabolic, cancer, and immunology, and also conducts research in animal health and animal agriculture. Lilly supports patient outcomes and education through a philanthropic foundation that funds programs in underserved communities, including STEM education in Indianapolis.

Highland Capital Partners is a Massachusetts-headquartered global venture capital firm that invests in seed, early and growth-stage consumer and enterprise technology companies. It maintains offices in Boston, Silicon Valley and Shanghai and has raised substantial capital and backed more than 225 companies across consumer and enterprise technology, supporting entrepreneurs with a focus on building lasting businesses. The firm also runs mentorship initiatives such as Summer@Highland. Its European presence, Highland Europe, founded in 2012, targets rapidly growing internet, mobile and software companies in Europe and works closely with the firm to pursue primary investments as well as acquisition finance or lead secondary transactions.

SOSV is a global venture capital firm that supports early-stage startups through active, founder-first development programs. Its flagship initiatives HAX and IndieBio provide facilities, engineering resources, services, and laboratory equipment to accelerate product development and prepare companies for subsequent funding rounds. SOSV focuses on deep technology across health, environmental, and cross-border software sectors, aiming to solve human and planetary health challenges. In addition to providing capital, the firm emphasizes intensive programmatic support to help portfolio companies move quickly from seed toward growth, including customer acquisition and scale. The firm operates globally with a bias toward startups targeting rapid international expansion, especially in Asia, and tends to back a small cohort of high-potential companies to accelerate their progress and attract leading investors.

Bessemer Venture Partners is a long-established venture capital firm based in Redwood City, California, founded in 1911. The firm makes early-stage and growth investments across software, cloud, fintech, cybersecurity, artificial intelligence, biotech, healthcare, consumer services, marketplaces and other technology sectors, with global reach in the United States, Israel, Canada and India. It supports founders from seed to scale, providing strategic guidance and capital to build durable businesses. The firm has backed notable companies such as Pinterest, LinkedIn, Shopify, Yelp, Twilio, DocuSign and Wix, among others, reflecting a history of funding transformative technology companies. Bessemer Venture Partners operates as a registered investment adviser and pursues opportunities across information technology, hardware and services worldwide.

Third Rock Ventures is a Boston-based venture capital firm that specializes in start-up and early-stage investments in life sciences companies, including biotechnology, pharmaceuticals, medical devices, diagnostics, therapeutics, and related information technology and data applications. Founded in 2007, the firm focuses on transformational ventures in the United States and commonly makes substantial initial investments, often leading rounds and pursuing strategic collaborations with larger pharmaceutical and biotechnology companies. It emphasizes active involvement in its portfolio, sometimes taking key management roles to accelerate development, and seeks to support companies through strategic partnerships, milestones, and scale-up efforts. While headquartered in Boston, it maintains a presence in San Francisco to engage with the broader life sciences ecosystem.

Hyperplane I, established in 2016, is a venture capital fund based in Boston, Massachusetts. It invests in exceptional founders developing machine intelligence and data companies, focusing on those that leverage AI, sensor technology, and cloud computing to tackle complex global challenges. The fund, managed by Hyperplane Venture Capital, was founded by Vivjan Myrto, John Murphy, and Brendan Kohler in 2015.

Morningside is a venture capital firm based in the greater Boston area, specializing in investments in companies that focus on innovative science and technology. Established in 1986 as a family office for the Chan family, Morningside emphasizes a long-term approach to company-building and maintains a strong commitment to ethical practices. The firm is staffed by a team of experienced investment professionals with expertise in various sectors, including life sciences, digital health, artificial intelligence, materials, and technology. In addition to its investment activities, Morningside is dedicated to philanthropic efforts, supporting education, research, and healthcare initiatives such as the Harvard T.H. Chan School of Public Health, UMass Chan Medical School, and the MIT Morningside Academy for Design.

Samsara BioCapital is a venture capital firm based in Palo Alto, California, that focuses on biotechnology and life sciences companies in the United States. The firm seeks to invest in pharmaceutical and biotechnology ventures, including oncology and other healthcare technologies, with a goal of supporting entrepreneurs in turning ideas into developed therapies. It emphasizes collaboration with ambitious partners and aims to advance biotech innovation and important new therapies by providing capital and advisory support. The organization also operates as a registered investment adviser, offering investment advisory services to guide portfolio companies through growth and development.

Launchpad Venture Group, based in Boston, Massachusetts, is an angel investment group that funds early-stage, technology-driven startups. They focus on innovative companies addressing substantial market opportunities, primarily in sectors like software, IT, healthcare, and clean-tech. The group offers both financial and human capital, leveraging its network of potential customers, service providers, and future financing sources to support entrepreneurs in building successful businesses.

Battery Ventures is a technology-focused investment firm founded in 1983 and based in Boston, Massachusetts. It engages in venture capital and private equity investments in technology companies, with emphasis on software (including application and infrastructure software), IT infrastructure technologies, consumer internet and mobile services, industrial technologies, and life science tools. The firm seeks to back category-defining businesses with potential for scalable growth, often supporting companies through multiple stages and across select global regions.

Accel is a venture capital firm founded in 1983 in Palo Alto, California, that backs early and growth-stage technology startups worldwide. It concentrates on software, cloud, data, mobile, digital media, and adjacent sectors, including consumer and enterprise technology, fintech, security, and healthcare. The firm supports entrepreneurs with long-term guidance and the resources needed to build world-class, category-defining companies. Accel maintains offices in Palo Alto, San Francisco, London, and Bangalore, and has backed a broad portfolio featuring notable companies such as Atlassian, Facebook, Dropbox, Slack, Spotify, and Cloudera.

Founded in 2015, Underscore.VC is a Boston-based venture capital firm focusing on seed to series A investments. It primarily invests in technology companies with an emphasis on sensor-related technologies, software for factories and home automation, healthcare infrastructure, data storage databases, and cloud-based marketing/commerce software.

Walnut Ventures is a venture capital firm headquartered in Boston, Massachusetts, that focuses on investing in seed and early-stage companies, primarily within the information technology sector. The firm is particularly interested in areas such as home entertainment software, data processing, online services, and internet marketing. It typically invests between $250,000 and $1 million in companies located in the New England region and aims to take an active role by seeking a board seat in its portfolio companies. Established in 1997, Walnut Ventures comprises a network of experienced entrepreneurs and investors who are dedicated to helping talented entrepreneurs build sustainable businesses in rapidly growing markets. The firm offers not only financial investment but also support in refining business plans, enhancing management teams, developing financing strategies, and facilitating strategic partnerships.

Venrock is a Palo Alto-based venture capital firm founded in 1969 as the venture capital arm of the Rockefeller family. It concentrates on seed and early-stage investments in technology and healthcare, with interests spanning information technology, life sciences and related sectors in the United States. The firm has supported a broad portfolio of companies, including Apple, Intel, Illumina, DoubleClick, Athenahealth, Gilead Sciences, Nest, SlideShare and Tudou. Venrock emphasizes long-term partnerships with entrepreneurs, combining hands-on venture support with rigorous data analysis to help startups grow into enduring companies.

LaunchCapital, established in 2008, is a venture capital firm headquartered in New Haven, Connecticut, with additional offices in Boston, New York, and San Francisco. The company invests in early-stage startups, focusing on seed rounds with investments typically ranging from $50,000 to $150,000. LaunchCapital supports entrepreneurs across various sectors, including commerce, marketplace, consumer, media, entertainment, enterprise software, emerging tech, data, finance, healthcare, and medical technology. The firm employs two distinct investment strategies: LaunchCapital Ventures, which follows a traditional equity model for high-growth opportunities, and LaunchCapital Small Business, which offers a blend of equity and debt financing for businesses with linear growth expectations and local or regional reach.

Clean Energy Ventures is a venture capital firm focused on seed and early-stage investments in climate technology and advanced energy innovations. The firm targets technologies and business model innovations that address climate change and greenhouse gas emissions, with emphasis on energy storage, grid connectivity, renewable energy production, clean transportation, and the water-energy nexus. It seeks scalable solutions ready for commercial deployment and supports them with capital and guidance to accelerate growth. Headquartered in Boston, Massachusetts, Clean Energy Ventures is the venture capital arm of Clean Energy Venture Group and concentrates its activity in the United States and Canada, drawing on the group’s network and operational experience to help portfolio companies scale.

Northpond Ventures is a science-driven venture capital firm based in Bethesda, Maryland, with additional offices in San Francisco, California, and Cambridge, Massachusetts. Founded in 2018, the firm concentrates its investments in life sciences, diagnostics, therapeutics, digital health, and related technologies, including AI and machine learning applications in biotech and medical fields, as well as environmental and other emerging technologies. It seeks to back early- and growth-stage companies that advance biomedical research, diagnostics, medical devices, and technology-enabled health solutions. The firm operates as a registered investment adviser and emphasizes building a better tomorrow through science-driven investing. It focuses on strategy, value creation, and supporting companies at the intersection of life sciences and technology, aiming to accelerate innovations that improve health outcomes.

Omega Funds is a Boston-based venture capital and private equity firm founded in 2004 that concentrates on early-stage investments in healthcare and biotech across North America and Western Europe, backing companies in life sciences, digital health, immunology, rare diseases, precision medicine, oncology, cybersecurity, and software-as-a-service.

Deerfield Management is a New York-based investment firm established in 1994 that focuses on healthcare. It operates across investment, information, and philanthropy to support the healthcare ecosystem. The firm provides private and public investments and offers long-term, structured capital to both public and private healthcare companies. Its portfolio spans life sciences, medical devices, diagnostics, digital health, and health services. As an investment adviser, it seeks opportunities in healthcare products and services and aims to accelerate innovation by combining capital with industry insight.

E14 Fund is a venture capital firm based in Cambridge, Massachusetts, that focuses on seed-stage investments in deep technology companies. It emphasizes commercializing MIT-originated ideas by providing capital, strategic guidance, and access to a broad network of advisors, including investors, industry experts, and entrepreneurs, to move technologies from lab to market and scale them for impact. The firm backs a diverse range of sectors, including biotechnology, smart cities, consumer electronics, and manufacturing, and seeks to connect founders with the resources needed to raise subsequent rounds and accelerate growth. Through its ecosystem, E14 Fund aims to bridge academia and industry, supporting entrepreneurs who leverage research and innovation to create scalable solutions.

Threshold Ventures is a venture capital firm based in Menlo Park, California. It pursues a high-conviction, early-stage investment strategy and partners with entrepreneurs to build technology-driven companies in consumer, enterprise, and healthcare sectors. The firm provides venture and growth capital to technology companies and has historical ties to the broader Draper Fisher Jurvetson network. Threshold focuses on supporting early-stage ventures across software, consumer, and healthcare technologies, and seeks to back innovative teams aiming to reach market leadership.

Founded in 2016, Glasswing Ventures is a venture capital firm based in Boston, Massachusetts. It specializes in investing in early-stage companies focused on artificial intelligence software, intelligent enterprise frontier tech, security software, and network security sectors. The firm typically invests between $2 million to $3 million in the United States, with a focus on the East Coast, particularly New York City Area and Boston Area.

Boston Seed Capital is a seed- and early-stage venture capital firm based in Massachusetts, with offices in Boston and Wellesley Hills. Founded in 2010, it focuses on funding internet-enabled and technology-driven startups across the United States, including consumer products, B2B software as a service, cybersecurity, e-commerce, big data, artificial intelligence and machine learning, marketplaces, and related services. The firm backs early-stage companies, often in information technology and SaaS, providing capital and strategic support to help companies scale from initial traction to growth.

Founded in 1996, MPM Capital is a global investment firm focused on the healthcare and life sciences sectors. It specializes in early-stage investments, typically ranging from $5 million to $50 million, with a primary focus on biotechnology, oncology, medical technology, and specialty pharma. The firm invests globally, with a concentration in North America, Europe, and Asia-Pacific.

Mass General Brigham Ventures is the venture capital arm of Mass General Brigham, an integrated academic health care system. Founded in 2008, it invests in early-stage healthcare companies, including drugs, devices, diagnostics, digital health, and other life science technologies developed within the Mass General Brigham ecosystem. The firm pursues both direct investments in incubation, seed, startup and early venture rounds and fund-of-fund investments in venture capital funds. Its aim is to translate internal research and technologies into commercial solutions that improve patient care and healthcare delivery, through partnerships and out-licensing to market players when appropriate. Based in the Boston area, with operations in Somerville and Cambridge, Massachusetts.

Longwood Fund is a Boston-based venture capital firm that creates and invests in science-based companies developing novel solutions for important medical problems. The firm concentrates on healthcare and life sciences, including biotechnology, pharmaceuticals, oncology, and healthtech, supporting ventures from discovery through development with capital and strategic guidance. Established in 2010, Longwood seeks to translate laboratory advances into clinically meaningful products by backing companies built on strong scientific foundations and collaborations with leading research institutions. Through its investments, the firm aims to advance therapies and technologies that address unmet medical needs and improve patient outcomes.