Top investors in Massachussets
Showing 1-50 of 2209 investors
RA Capital Management
RA Capital Management is a Boston-based investment firm that pursues evidence-based investing across public and private healthcare, life sciences, and planetary health sectors. The firm supports the growth of innovative companies from seed to later-stage financings, focusing on drugs, medical devices, diagnostics, biotech services, and research tools. RA Capital combines a data-driven research platform, TechAtlas, with a collaborative investment approach and a healthcare incubator, Raven, to help management teams advance ideas from inception through development and commercialization. It frequently co-invests, takes board seats, and participates in follow-on financings, aiming to back ventures that improve patient outcomes and reduce costs. The firm emphasizes US and European opportunities, maintains a multi-stage investment scope, and is headquartered in Boston.
Made 115 investments in Massachussets
MassVentures
MassVentures is a Massachusetts-based venture capital firm founded in 1978 that provides seed and early-stage funding to high-growth startups. It supports ventures as they move from concept to commercialization and offers mentorship, strategic guidance, and access to industry connections to help build scalable businesses. The firm backs innovations across quantum computing, clean energy, artificial intelligence, biotechnology, advanced materials, advanced manufacturing, and robotics, and operates programs such as MV Capital, MV Accelerate, and MV Spinouts to fund companies, accelerate commercialization, and translate academic research into viable enterprises. By leveraging the Massachusetts innovation ecosystem, MassVentures aims to bolster entrepreneurs outside traditional hubs and foster sustained growth within the regional economy.
Made 177 investments in Massachussets
Alumni Ventures
Alumni Ventures is a venture capital firm headquartered in Manchester, New Hampshire, that expands access to venture investing for accredited individuals by co-investing with leading venture capital firms and enabling participation through various structures such as funds, syndicates, and investment clubs. It collaborates with top firms including Andreessen Horowitz, Sequoia, and Y Combinator and supports opportunities across pre-seed to growth stages, across multiple sectors and geographies. The firm emphasizes rigorous due diligence, transparency, and diversification, leveraging a broad network of alumni investors and partners to connect founders with strategic capital and resources. With a global footprint and active involvement in the venture ecosystem, Alumni Ventures aims to broaden participation in venture capital while maintaining disciplined, founder-friendly investing.
Made 122 investments in Massachussets
Atlas Venture
Atlas Venture is a Cambridge, Massachusetts-based biotechnology investment firm that partners with life science entrepreneurs to translate scientific discoveries into medicines. With more than 30 years of experience, the firm focuses on creating and building early-stage biotech companies, providing capital, mentorship, and strategic guidance to advance therapies from concept to clinic. Atlas Venture concentrates on biopharmaceuticals, therapeutics, and related life sciences technologies, seeking to lead and support companies through development milestones and to realize value through IPOs, acquisitions, or partnerships. The firm emphasizes collaboration with founders to build scalable businesses that address unmet medical needs and accelerate medical innovation.
Made 202 investments in Massachussets
Morningside Group
Morningside Group is a Boston-area venture capital firm founded in 1986 as a family office for the Chan family. It makes long-term investments in companies applying novel science and technology, with expertise in life sciences, digital health, AI, materials, and technology, and a commitment to ethical business practices. The firm supports education, research, and healthcare through charitable initiatives with partners including Harvard T.H. Chan School of Public Health, UMass Chan Medical School, and MIT Morningside Academy for Design.
Made 50 investments in Massachussets
General Catalyst
General Catalyst is a venture capital firm that backs technology-driven companies across stages, providing early-stage and growth equity investments, capital, and strategic guidance to help startups scale. Founded in 2000, it emphasizes resilience and applied AI, supporting entrepreneurs across healthcare, fintech, consumer technology, enterprise software, and other sectors. The firm aims to accelerate growth by pairing portfolio companies with experienced mentors and networks, operating globally from multiple offices and managing substantial assets to support scale.
Made 145 investments in Massachussets
Flagship Pioneering
Flagship Pioneering is a Cambridge, Massachusetts–based venture capital firm that conceives, creates, resources, and grows first‑in‑category companies to transform human health, biology, medicine, energy, and agriculture. It combines scientific capacity with entrepreneurial leadership and capital management to systematically build ventures from science, pursuing seemingly unreasonable ideas toward transformational outcomes through an evolutionary approach. The firm fosters a culture of exploration to invent medicines, intelligence solutions, and preemptive health strategies, alongside innovations in agriculture. Its portfolio includes Moderna, Tessera Therapeutics, Generate:Biomedicines, Inari Agriculture, Quotient Therapeutics, and Lila Sciences, and it collaborates with industry and research partners to accelerate innovation with companies and institutions such as AWS, Pfizer, GSK, IQVIA, and Thermo Fisher.
Made 138 investments in Massachussets
OrbiMed
OrbiMed is a global healthcare investment firm focused on supporting the development of therapies, medical devices, diagnostics, and health IT. Established in 1989, it manages a broad investment platform across venture capital, private equity, and public equity, targeting opportunities from early-stage startups to mature companies. The firm backs companies across biopharmaceuticals, biotechnology, life sciences, and digital health, providing financing and strategic resources to accelerate innovation. With a multinational presence and offices in New York, San Francisco, Mumbai, Herzliya, Shanghai, and beyond, OrbiMed pursues a diversified portfolio of healthcare companies worldwide.
Made 81 investments in Massachussets
Invus
Invus is a global investment firm established in 1985 that partners with owner-led and growth companies to create lasting value. It emphasizes long-term relationships, aligns incentives with management, and provides capital and strategic guidance through a flexible structure that supports a wide range of situations. The firm manages multi-billion-dollar evergreen capital and operates from offices in New York, London, Paris, and Hong Kong.
Made 55 investments in Massachussets
Mission BioCapital
Mission BioCapital is a life science venture capital firm that provides early-stage capital and hands-on support to founders from concept through clinical development. Its leadership team has a long history of collaboration and a track record of launching dozens of early-stage life science ventures, and the firm is known for its deep technical expertise and active, founder-friendly mentorship. With offices in San Francisco and Cambridge, Massachusetts, Mission BioCapital operates in regions rich in research, discovery, and venture activity. The firm offers programs such as the Platinum Program, which provides up to $500,000 in funding, lab space, mentorship, and access to drug discovery, legal, and financial services. It collaborates with corporate and strategic partners to accelerate development and help translate scientific discoveries into therapies, including relationships with AbbVie and Ono Venture Investment. Founded in 2009, Mission BioCapital focuses on early-stage life sciences and biotechnology companies and emphasizes collaboration, innovation, and support for founders to address unmet medical needs.
Made 19 investments in Massachussets
ARCH Venture Partners
ARCH Venture Partners is a Chicago-based venture capital firm founded in 1986 that concentrates on early-stage, technology- and science-driven startups, with a strong emphasis on life sciences, biotechnology, pharmaceuticals, healthcare, and related fields. The firm partners with scientists and entrepreneurs to bring academic innovations to market, offering strategic guidance, a deep network, and hands-on involvement beyond capital. It has funded and helped commercialize technologies developed at universities and national laboratories, and maintains a national and international investing footprint with offices in Chicago and Seattle. ARCH has raised multiple funds totaling over three billion dollars and backed more than 150 companies in the venture rounds, reflecting a track record of catalyzing discoveries and building durable companies in science sectors.
Made 82 investments in Massachussets
Founder Collective
Founder Collective is a venture capital firm that backs seed and early-stage technology startups across sectors, with a focus on founder alignment, capital efficiency, and a long-term partnership approach. It supports companies from idea stage through IPO, emphasizing authentic founder–investor relationships, intrinsic value, and pragmatic, stage-focused investing. The firm is headquartered in Cambridge, Massachusetts, with offices in Boston and New York City, including the SoHo area, and operates across the United States and beyond. Founded in 2009 by a group of successful entrepreneurs, it is led by general partners Micah Rosenbloom, Amanda Herson, and David Frankel.
Made 39 investments in Massachussets
New Enterprise Associates
New Enterprise Associates is a venture capital firm founded in 1977 and headquartered in Menlo Park, California. It provides funding and hands-on support to technology and healthcare startups across stages, from seed to growth and IPO. The firm partners with founders to address technical challenges, guide product development, and expand markets, offering domain expertise and long-term collaboration. Its investment focus spans software, consumer technology, medical devices, healthcare technology, life sciences, artificial intelligence, and related sectors across the United States, Asia, and other regions. NEA emphasizes enduring relationships and collaborates closely with portfolio companies to build transformational businesses.
Made 124 investments in Massachussets
Third Rock Ventures
Third Rock Ventures is a Boston-based venture capital firm that concentrates on early-stage investments in life sciences and healthcare. It backs biotechnology, pharmaceuticals, medical devices, diagnostics, and related information technology companies with high growth potential, providing substantial initial capital and active support to accelerate development and commercial success. The firm emphasizes strategic collaborations and seeks meaningful involvement in portfolio companies, including potential leadership roles, to advance medicines, therapies, and diagnostics. By positioning its investments within the U.S. life sciences landscape, Third Rock Ventures aims to help startups translate scientific breakthroughs into clinically meaningful products and outcomes.
Made 72 investments in Massachussets
Khosla Ventures
Khosla Ventures is a California-based venture capital firm that invests in technology companies across stages, with a focus on artificial intelligence, healthcare, sustainability, climate tech, digital health, and consumer technology. Based in Menlo Park, the firm seeks startups with innovative technologies or business models and provides strategic guidance to help build lasting companies, offering active support to founders to accelerate growth and scale in both early- and later-stage opportunities.
Made 49 investments in Massachussets
Accomplice
Accomplice is an early-stage venture capital firm headquartered in Cambridge, Massachusetts. It invests in technology startups across cybersecurity, esports, data analytics, SMB software, emerging hardware platforms, and marketplaces. The firm employs a community-driven approach, leveraging networks and platforms such as AngelList, Boston Syndicates, Maiden Lane, Spearhead, BOSS, Rev, and TUGG to identify and back founders. While the majority of its investments are in the Boston area, the portfolio spans the United States, Canada, and Europe. Formerly part of Atlas Venture, the technology group was renamed Accomplice in 2014 as the firm refined its focus on early-stage technology companies.
Made 82 investments in Massachussets
Spark Capital
Spark Capital is a venture capital firm founded in 2005 with offices in San Francisco, Boston, and New York City. It provides early-stage and growth funding to startups across sectors including consumer, software, fintech, media, and internet services. The firm emphasizes a founder-friendly, collaborative approach and seeks to back ambitious teams that aim to reshape markets. Its portfolio includes notable companies such as Twitter, Discord, Oculus, Warby Parker, and Tumblr, illustrating a track record of supporting product-driven ventures across stages.
Made 69 investments in Massachussets
SOSV
SOSV is a global venture capital firm headquartered in Princeton, New Jersey, that backs deep-tech startups across seed to growth stages with emphasis on human and planetary health. It provides founders with labs, offices, expert teams, mentorship, investor networks, and accelerator-style programs to accelerate product development, testing, commercialization, and fundraising. SOSV operates three deep-tech facilities, including SOSV SF & NY (IndieBio) and HAX in Newark, and supports a portfolio of more than 800 companies across 58 countries. The firm has a broad global footprint with offices in San Francisco, New York, Newark, and Princeton, has raised over 7.5 billion for its portfolio, and makes approximately 60 pre-seed investments annually alongside many follow-on rounds. It seeks co-investors and limited partners to join its network, and pursues cross-border opportunities, notably in Asia, to accelerate growth and fundraising for its startups.
Made 67 investments in Massachussets
Casdin Capital
Casdin Capital is a New York-based venture capital firm founded in 2012 by Eli Casdin. The firm focuses on life sciences and healthcare, including biotechnology, oncology, digital health, agtech, and related areas, and invests in private companies across stages from early to late, seeking opportunities that leverage data analysis, genomics, and precision medicine. It emphasizes partnerships with experienced teams and maintains a long-term investment horizon, and applies its data expertise to inform investment decisions while upholding ethical considerations in the industry.
Made 52 investments in Massachussets
Hyperplane Venture Capital
Hyperplane Venture Capital is a Boston-based early-stage technology investment firm that backs exceptional founders building machine intelligence and data-driven companies. The firm concentrates on startups leveraging artificial intelligence, machine learning, sensor technology, cloud computing, automation, robotics, and related areas, seeking solutions at the intersection of perception, communication, intelligence, and insight. It often makes early checks and emphasizes long-term partnerships to help portfolio companies scale from inception toward enduring market impact. Portfolio focus includes AI-enabled infrastructure, autonomous systems, robotics, secure collaboration, supply chain visibility, and other AI-powered workflows across diverse industries. The firm partners with founders to shape solutions and build durable, iconic businesses where AI intersects with real-world workflows and infrastructure.
Made 61 investments in Massachussets
.406 Ventures
.406 Ventures is a Boston-based venture capital firm that focuses on early-stage investments in information technology, security and infrastructure, software, and technology-enabled business services, with a strong emphasis on cybersecurity, cloud software, digital health, data analytics, fintech, AI and big data. The firm primarily backs B2B and enterprise IT companies and often acts as lead or first institutional investor, seeking to partner with founders to scale growth. It targets companies in the Northeast United States, beginning with initial commitments typically between $2 million and $5 million and total investments between $6 million and $10 million per company, with follow-on support as the company grows. The team emphasizes hands-on involvement, leveraging deep industry experience and networks to help portfolio companies succeed, including board representation. Founded in 2005 and headquartered in Boston, the firm combines operational know-how with capital to create value for entrepreneurs and investing partners.
Made 61 investments in Massachussets
TCG Crossover
TCG Crossover is a science-driven healthcare investment firm focused on supporting the development of disruptive medicines. It invests in both private and public companies led by entrepreneurs pursuing better treatment options and maintains a portfolio aimed at advancing innovative pharmaceutical solutions. Based in Palo Alto, California, with investment teams in Palo Alto and New York City, the firm targets investments in the United States and Europe, emphasizing healthcare, digital health, and health technology sectors.
Made 16 investments in Massachussets
Samsara BioCapital
Samsara BioCapital is a biotechnology-focused venture capital firm based in Palo Alto, California, established in 2016. The firm concentrates on funding and supporting biotechnology companies and transformative therapeutics across the United States, leveraging multidisciplinary expertise and strategic partnerships to accelerate clinical and commercial breakthroughs. As a registered investment adviser, Samsara BioCapital combines scientific insight with strategic resources to help entrepreneurs advance innovative medicines.
Made 30 investments in Massachussets
Deerfield Management
Deerfield Management is a New York–based healthcare investment firm focused on advancing health outcomes through investment, research, and philanthropy. It invests across public and private markets in biotechnology, pharmaceuticals, diagnostics, healthcare services, medical devices, and digital health, using flexible funding models and strategic partnerships to support companies at various stages and to foster innovation. The firm operates an internal research and development engine to accelerate discovery and development, and maintains a philanthropic foundation that funds education, healthcare access, and initiatives to improve health outcomes. Through collaboration with strategic partners and a commitment to data-driven insights, Deerfield Management seeks to advance healthcare technology and services while building a broader, sustainable health ecosystem.
Made 45 investments in Massachussets
Boston Seed Capital
Boston Seed Capital is a venture capital firm based in the Boston area, with a Wellesley Hills, Massachusetts office, that provides seed- and early-stage funding to internet-enabled startups across the United States. It focuses on consumer goods, business services, and technology, including information technology, SaaS, cybersecurity, e-commerce, big data, marketplaces, artificial intelligence and machine learning, and esports. The firm adopts a hands-on, founder-focused approach, collaborating with entrepreneurs from concept through scale, drawing on experience in supporting both consumer and business-to-business software ventures. Founded in 2010, it aims to help early-stage companies grow in a competitive technology landscape.
Made 49 investments in Massachussets
Beacon Angels
Beacon Angels is a Boston-based angel investment group that backs early-stage, fast-growing companies in New England. It provides capital and strategic support to entrepreneurs, with regular monthly meetings to review opportunities. Membership is open to accredited investors seeking portfolio growth, and the group is a member of the Angel Capital Association.
Made 18 investments in Massachussets
Safar Partners
Safar Partners is a venture capital investment firm based in Cambridge, Massachusetts, founded in 2018. It funds technology companies at seed to growth stages in sectors including cleantech, advanced materials, artificial intelligence and information technology, robotics, and life sciences. The firm sources opportunities through deep relationships with leading universities such as MIT, Harvard, and the University of Rochester, and provides guidance to portfolio companies as they scale. Safar Partners operates as a registered investment adviser and emphasizes applying ESG considerations within its investment approach.
Made 20 investments in Massachussets
Launchpad Venture Group
Launchpad Venture Group is a Boston-based angel investor network that provides financial and human capital to early-stage science and technology startups. Founded in 2001, it supports ventures across software, information technology, web and mobile sectors, medical devices and diagnostics, healthcare IT, networking and telecom, and clean-tech and renewable energy, with a focus on U.S. opportunities in New England. The group emphasizes mentorship alongside funding, seeking to build long-term relationships with innovative founders. Through its network, Launchpad Venture Group connects portfolio companies to potential customers, service providers, partners, and future sources of financing. It has invested more than $125 million in over 150 startups, aiming to help entrepreneurs scale and succeed.
Made 67 investments in Massachussets
Northpond Ventures
Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland, with additional offices in San Francisco and Cambridge. The firm focuses on investing in life sciences, diagnostics, digital health, health technology, AI and machine learning, and related technology sectors, supporting breakthrough science and technology-driven companies from early to growth stages. Its portfolio targets companies that aim to deliver meaningful advances in healthcare and technology, and the firm emphasizes building a better tomorrow through strategic capital and resources that help entrepreneurs develop and scale impactful solutions across life sciences, technology and affiliated industries.
Made 28 investments in Massachussets
Pillar VC
Pillar VC is an early-stage venture capital firm based in Boston, founded in 2016 by a group of CEOs who have built successful companies. It backs technically driven founders across artificial intelligence, biotechnology and deep tech from inception, partnering with teams to accelerate breakthrough technologies. The firm manages substantial capital, including around 500 million in assets and a 175 million Fund IV, and has invested in roughly 90 companies, about half with university roots. Notable portfolio companies include Wayfair, Ginkgo Bioworks, DraftKings, Abridge, ButcherBox and Flywire.
Made 41 investments in Massachussets
MPM BioImpact
MPM BioImpact is a venture capital firm based in Boston that invests in biotechnology, healthcare, and life sciences companies across the entire drug development process, from early research to public markets. With over 30 years of experience, the firm backs private and public companies aiming to translate scientific breakthroughs into life-saving medicines. It emphasizes building and supporting ventures that improve patient outcomes, drawing on a team of industry experts and entrepreneur partners. Its portfolio includes Orna Therapeutics, developing circular RNA medicines, Aktis Oncology, pioneering radio-pharmaceuticals, and Reunion Neuroscience, advancing psychedelic-inspired therapies for mental health. MPM BioImpact has demonstrated a track record of backing companies that produce FDA-approved drugs, engage in M&A activity, and pursue initial public offerings, reflecting a continued commitment to advancing innovative therapies.
Made 68 investments in Massachussets
CRV
CRV is a Palo Alto–based early-stage venture capital firm that traces its roots to 1970 as Charles River Ventures. The firm pursues a hands-on, value-added approach to back seed through Series B technology, consumer, healthcare and enterprise companies across North America. With a long history as one of the industry’s oldest venture firms, CRV emphasizes deep collaboration with founders, mentorship on strategy, product development, customer acquisition and IP protection to help portfolio companies reach growth milestones. It maintains offices in Cambridge, Massachusetts, and Menlo Park, California, and has supported a broad set of startups that have gone on to become category leaders. CRV aims to act as a trusted, long-term partner beyond capital, guiding companies from inception to IPO and beyond.
Made 76 investments in Massachussets
Prelude Ventures
Prelude Ventures is a venture capital firm based in San Francisco, California that funds early-stage startups developing solutions to mitigate climate change. The firm targets a broad range of sectors, including the built environment, carbon management, compute, energy, food and agriculture, manufacturing and industrials, and mobility, aiming to support category-defining companies at their earliest stages. By aligning investment with climate impact, Prelude Ventures seeks to accelerate innovation and foster impactful technologies that address climate challenges.
Made 24 investments in Massachussets
E14 Fund
E14 Fund is a Cambridge, Massachusetts-based venture capital firm that concentrates on seed and early-stage investments in deep technology companies, with a particular focus on startups originating from MIT. It supports portfolio companies from pre-seed to Series A, helping translate academic research into commercial products and scale technologies for real-world impact. Leveraging a broad network of advisors, industry experts, and entrepreneurs, it assists portfolio firms with strategy, fundraising, and market development. The firm backs ventures across sectors such as artificial intelligence, robotics, biotechnology, smart cities, and manufacturing, and aims to build inclusive communities by partnering with diverse founders. E14 Fund positions itself as an early partner that connects founders with resources and opportunities within its ecosystem.
Made 27 investments in Massachussets
EcoR1 Capital
EcoR1 Capital is a San Francisco-based investment firm focused on the biotechnology sector. As a venture capital investor and registered investment adviser, it partners with entrepreneurs developing novel medicines and life-saving therapeutics, supporting discovery and development through long-term collaborations. The firm emphasizes a molecular understanding of biology and chemistry to identify promising opportunities with potential patient impact, investing across early-stage and later-stage biotech companies. It backs innovative ventures addressing unmet medical needs and aims to accelerate translational research to bring transformative therapeutics to patients.
Made 33 investments in Massachussets
Lux Capital
Lux Capital is a venture capital firm based in New York City with a presence in Silicon Valley that backs early-stage and growth companies applying scientific research to commercial applications across sectors including artificial intelligence, biotechnology, advanced materials, electronics, aerospace, space technology, energy, infrastructure, and life sciences. The firm partners with technical founders and research-driven teams to translate complex innovations into scalable businesses, providing capital alongside strategic input on product development, company building, and long-term positioning. It evaluates opportunities based on underlying science, potential industry impact, and feasibility of execution over extended horizons.
Made 38 investments in Massachussets
Venrock
Venrock is a venture capital firm founded in 1969 as the venture capital arm of the Rockefeller family. It concentrates on technology and healthcare, investing in seed and early-stage companies as well as growth opportunities, and has backed influential firms such as Apple Computer, Intel, Illumina, Nest, and SlideShare. The firm supports portfolio companies across information technology, life sciences, software, cybersecurity, and emerging technologies, pursuing disruptive innovations and long-term growth through partnerships with entrepreneurs to build enduring companies.
Made 87 investments in Massachussets
CVP Management
CVP Management is a venture capital firm focused on early‑stage technology investments, including seed and early Series A rounds. It concentrates on information technology infrastructure with emphasis on software applications, internet, digital media, digital marketing, vertical SaaS, cloud, embedded software, mobile, and financial services technologies. The firm typically invests from $0.1 million to $1 million, and for seed and Series A rounds from $1 million to $3.5 million, in companies with an enterprise value around $5 million. It prefers to hold a seat on the portfolio company board and to invest in preferred stock. The firm funds companies located in the Northeast corridor, especially Boston, New York, and Toronto, and began operation on June 1, 1998, with headquarters in Cambridge, Massachusetts, and an additional office in Boston.
Made 79 investments in Massachussets
Boxer Capital
Boxer Capital is a biotechnology investment firm that serves as the corporate venture capital arm of Tavistock Group. Based in the United States, the firm invests in public and private biotechnology and life sciences companies across the drug development lifecycle, from early discovery to commercial stage, with a focus on precision medicine and transformative medical advancements. Boxer Capital combines fundamental research with a multidisciplinary analysis of scientific, clinical, regulatory, and commercial factors to translate innovation into opportunity. It pursues opportunities across the full drug lifecycle and provides financial capital and strategic guidance to portfolio companies. The firm notes partnerships with companies such as Mirati Therapeutics and Pandion Therapeutics as examples of its collaborative approach.
Made 19 investments in Massachussets
Founders Fund
Founders Fund is a San Francisco-based venture capital firm that supports science and technology companies across seed to late-stage investments, with a global reach and a focus on transformative technologies. It has backed notable companies such as SpaceX, Palantir, Facebook and Airbnb, and pursues a founder-friendly approach that provides substantial support with minimal interference across sectors including software, artificial intelligence, aerospace, energy, health, cybersecurity, biotechnology, quantum computing, and consumer internet.
Made 23 investments in Massachussets
NextView Ventures
NextView Ventures is a Boston-headquartered venture capital firm founded in 2010 that makes seed and early-stage investments and operates a hands-on accelerator program. With offices in New York and San Francisco, it pursues a thematic investing approach across North America, supporting founders with mentorship and resources to build impactful companies. Its portfolio spans fintech, health, consumer and software sectors, among others, and the accelerator provides an initial investment and operational support for select pre-seed and seed startups, with the aim of helping companies scale from inception to growth.
Made 40 investments in Massachussets
Omega Funds
Omega Funds operates as a Boston-based venture capital investment firm focused on early-stage life sciences and healthcare opportunities in North America and Western Europe. It backs companies across biotechnology, pharmaceuticals, digital health, immunology, rare diseases, precision medicine, oncology, cybersecurity, and SaaS, and manages multiple venture funds including Omega Fund IV, V, VI, and VII. With offices in Boston and Geneva, Omega Funds collaborates with researchers and entrepreneurs to advance medical innovations and bring new therapies and products to patients, pursuing value through strategic support, potential exits, and long-term partnerships.
Made 30 investments in Massachussets
Longwood Fund
Longwood Fund is a Boston-based venture capital firm that backs science-driven healthcare and life sciences companies. Founded in 2010, it targets solutions for serious medical problems and often collaborates with technology originating from leading labs such as Harvard and MIT. The firm positions itself as a value-add investor, working closely with portfolio companies to translate research into patient therapies, with partners actively engaging as co-founders or senior executives when appropriate. Its focus spans healthcare, pharmaceuticals, biotechnology, and oncology, aiming to accelerate the journey from lab discovery to clinical impact.
Made 23 investments in Massachussets
LaunchCapital
LaunchCapital is a venture capital firm founded in 2008 that provides seed and early-stage funding across diverse industries, with a hands-on approach that includes mentorship and ongoing support for portfolio companies. Backed by prominent family offices such as the Pritzker/Vlock Family Office, it has invested in over 200 companies and pursues opportunities nationwide. The firm operates via two investment vehicles: LaunchCapital Ventures, which provides equity for growth opportunities, and LaunchCapital Small Business, which blends equity and debt to support near-term revenue and local or regional growth. Based in New Haven, Connecticut, LaunchCapital focuses on technology, consumer, and medical sectors, and seeks opportunities in commerce, marketplace, media, enterprise software and services, data, finance, healthcare, and related fields.
Made 57 investments in Massachussets
5AM Ventures
5AM Ventures is a San Francisco-based venture capital firm founded in 2002 by John Diekman and Andrew Schwab. It focuses on seed- and early-stage investments in life sciences and healthcare, including biopharmaceuticals, medical technology, and related research instruments, with activities across the United States and an office in Boston. The firm backs companies developing innovative medicines and life science tools, aiming to advance therapies and diagnostic technologies through hands-on partnership with founders.
Made 33 investments in Massachussets
Sequoia Capital
Sequoia Capital is a venture capital firm founded in 1972 and based in Menlo Park, California. It provides capital and strategic guidance to a limited number of technology companies across early, growth, and later stages, supporting ventures from idea or formation through scale. The firm emphasizes long-term partnerships, working closely with leadership teams to help with product development, market expansion, and strategic direction. With a global footprint, Sequoia backs ambitious founders building transformative businesses across software, information technology, internet, and other technology sectors.
Made 24 investments in Massachussets
Refactor Capital
Refactor Capital is a Burlingame, California-based venture capital firm that makes seed-stage investments in hard-tech and biotechnology startups across the United States. Led by solo general partner Zal Bilimoria, the firm typically writes early checks in the range of $1–$2 million. It backs founders developing transformative technologies across sectors such as artificial intelligence, infrastructure, applied biology, energy, aerospace, earth systems, manufacturing, and critical materials. Its portfolio includes Solugen, Astranis, and Coinbase. Refactor Capital aims to be the first investment source for promising startups, focusing on backing founders who refactor the real world.
Made 5 investments in Massachussets
Arkin Capital
Arkin Capital is an Israeli investment firm based in Herzliya that operates a multi-asset platform spanning venture capital, private equity, and hedge funds. With an AUM of over $2 billion, it pursues opportunities across life sciences, biotechnology, digital health, cybersecurity, fintech, and real estate, deploying capital through four main arms: Arkin Health, Arkin Equity, Arkin Tech, and Arkin Real Estate. The firm has a global reach, investing in Israel, North America, and Europe, and has backed more than 100 companies with multiple exits, reflecting a hands-on approach to supporting entrepreneurs and growth-stage companies worldwide.
Made 17 investments in Massachussets
Dementia Discovery Fund
The Dementia Discovery Fund is a global venture capital initiative focused on financing companies developing novel therapeutics and enabling technologies for dementia. It leverages a broad network of venture partners, scientists, entrepreneurs, and strategic collaborators to identify, fund, and develop biotech ventures that advance dementia research and treatment. With offices in London and Boston, the initiative mobilizes capital and expertise to accelerate scientific progress and seeks meaningful patient impact alongside financial returns. It is supported by a diverse base of partners from the pharmaceutical industry and philanthropic organizations.
Made 13 investments in Massachussets
Deep Track Capital
Deep Track Capital is a Greenwich, Connecticut-based venture capital firm focused on the biotechnology and life sciences sectors. It invests in public and pre-IPO biotechnology companies and emphasizes partnering with management teams, offering time, expertise, and a broad network in addition to capital. The firm aims to lead transactions, form large syndicates, and participate in rounds led by other qualified investors, providing strategic guidance and resources to portfolio companies.
Made 12 investments in Massachussets