.406 Ventures

Bluebird Kids Health is a pediatric healthcare provider that aims to build a healthier future for children. It offers a value-based care model, delivering comprehensive, evidence-based care tailored to each family's needs. Services include nutrition support, sleep training, treatments for common ailments like rashes and viruses, all aimed at reducing medical costs and providing personalized care. The company is also developing a proprietary technology platform, enhanced by AI, to proactively manage and coordinate treatment, further simplifying the experience for its clinical team.

RAD Security is a developer of an AI-driven cloud security platform that focuses on securing AI workloads and cloud infrastructure. Its advanced Cloud Detection and Response (CDR) system continuously monitors the behavior of containerized environments across hybrid-cloud settings. By proactively alerting clients to security issues and automatically addressing suspicious configurations, RAD Security helps organizations maintain compliance and quickly remediate vulnerabilities. The company's platform is designed to provide seamless, scalable protection, allowing businesses to navigate the complexities of AI security with confidence. Through its commitment to proactive security and continuous adaptation, RAD Security supports enterprises as they grow and evolve in an increasingly digital landscape.

Lynx is a fintech healthcare company that focuses on integrating financial solutions with healthcare services. Its API-connected platform facilitates healthcare payments, banking, and e-commerce, allowing businesses to offer tailored health-fintech solutions. By bridging the gap between health and finances, Lynx aims to enhance affordability, drive health engagement, and improve financial security for consumers. The company's technology infrastructure empowers partners to provide a seamless consumer experience, ultimately helping healthcare professionals improve patient outcomes and reduce administrative inefficiencies.

Mindgard is an artificial intelligence security company dedicated to protecting enterprise AI systems from evolving cyber threats that conventional security tools cannot adequately address. The company offers a sophisticated platform that enables organizations to assess, detect, and manage vulnerabilities in their AI models, addressing critical questions about AI risk and mitigation strategies. Mindgard’s solutions include security auditing, automated attack detection and defense mechanisms, and realistic scenario generation, all designed to ensure the integrity of AI-driven applications. By seamlessly integrating with existing cybersecurity frameworks, Mindgard allows businesses to automate and streamline the testing of AI vulnerabilities, thereby conserving resources and enhancing overall security. With over four years of development rooted in advanced research, the Mindgard platform empowers clients to confidently adopt AI technologies while safeguarding their digital assets and reputation in an increasingly complex AI landscape.

Nema Health operates an online trauma care platform that delivers cognitive processing therapy and other PTSD treatments through a virtual care center. The service enables individuals with post-traumatic stress disorder and related stress disorders to receive therapy from home, administered by PTSD-trained therapists. The platform focuses on comprehensive, long-lasting relief through remote care, combining professional psychotherapy with convenient, privacy-conscious access to treatment.

Heartbeat Health, Inc. is a healthcare technology company based in New York that specializes in cardiology services. Founded in 2017, it provides virtual-first solutions for the prevention and management of cardiovascular disease. The company utilizes a data-powered platform to facilitate real-time consultations between patients and physicians, enabling secure communication and collaboration on treatment and dietary advice. By offering tools that allow patients to monitor their heart health, Heartbeat Health aims to reduce cardiovascular risk and the likelihood of adverse health events. Its comprehensive approach enhances patient care and supports at-risk organizations through a focus on higher-value healthcare delivery.

Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Indico Data Solutions, Inc. specializes in developing enterprise artificial intelligence solutions aimed at automating processes involving unstructured content. Founded in 2013 and based in Boston, Massachusetts, the company offers a platform that enables businesses to create customized machine learning models using smaller datasets. Its tools facilitate the extraction and analysis of information from a variety of non-standard formats, including documents and images. By leveraging deep learning, Indico's platform enhances document-based workflows, addressing applications such as contract analysis, regulatory compliance, customer support automation, and more. This focus on automating labor-intensive tasks allows organizations to efficiently process large volumes of unstructured data and gain meaningful insights.

OncoveryCare operates a specialized virtual clinic dedicated to supporting survivors of critical illnesses, initially focusing on cancer patients post-treatment. Their mission is to provide comprehensive, whole-person care and foster community among survivors, aiming to reduce disparities in survivorship outcomes. Through their tailored platform, they enable patients to navigate survivorship more easily, offering tools and support to enhance their quality of life.

Wayspring is a value-based healthcare organization dedicated to delivering medical, behavioral health, and social support services to individuals with complex needs, particularly those affected by substance use disorders. The company employs a comprehensive and longitudinal model that emphasizes targeted outreach to members, strategic partnerships with providers, and community-based peer support. By focusing on individualized care and ensuring that patients' basic needs—such as access to healthcare, economic stability, and community connections—are met, Wayspring facilitates improved adherence to evidence-based medical practices and enhances health outcomes. This unique approach not only reduces healthcare waste but also empowers patients on their journey to wellness.

InStride Health is an outpatient care platform focused on delivering evidence-based treatment for pediatric anxiety and obsessive-compulsive disorder (OCD). The company offers a tailored virtual care journey that includes individual and group therapy, coaching, and medication management. This comprehensive approach is facilitated by a coordinated team of experienced psychiatrists, therapists, and coaches, ensuring that children and teenagers receive effective and accessible care. InStride Health aims to engage young patients and their families in their treatment, making mental health support both affordable and effective.

FamilyWell Health is a digital health company that integrates behavioral health services into obstetric practices. It offers a tech-enabled, collaborative care approach to address the maternal mental health crisis in the U.S., focusing on equitable and affordable access to mental health services for pregnant and postpartum patients. The company provides in-person and virtual care, including psychiatric consultations, licensed therapy, health coaching, and peer-to-peer text message support throughout the perinatal journey. It also guides providers on medication management, ensuring easy access to mental health care for patients.

Nema Health operates an online trauma care platform that delivers cognitive processing therapy and other PTSD treatments through a virtual care center. The service enables individuals with post-traumatic stress disorder and related stress disorders to receive therapy from home, administered by PTSD-trained therapists. The platform focuses on comprehensive, long-lasting relief through remote care, combining professional psychotherapy with convenient, privacy-conscious access to treatment.

Diana Health operates a network of contemporary women’s health practices that collaborate with hospitals to transform maternity and women’s healthcare delivery. The company offers a personalized care platform that integrates clinical services, education, and wellness support, aiming to improve clinical outcomes and streamline operations. Its model places women at the center of decision‑making, empowering them to prepare for childbirth and parenting in a way that aligns with their individual needs and preferences.

Better Life Partners Inc. is a healthcare company based in Hanover, New Hampshire, dedicated to providing comprehensive support for individuals struggling with opioid use disorder in the United States. Established in 2018, the company offers a range of services, including medication-assisted treatment, counseling, peer coaching, and group sessions. Better Life Partners focuses on delivering personalized healthcare to vulnerable populations, utilizing technology to create customizable care plans that ensure effective and reliable service delivery. By integrating medical and behavioral healthcare, the company addresses the needs of those affected by addiction, facilitating their recovery through a combination of telehealth, community-based support, and innovative care approaches. With additional offices across New Hampshire, Better Life Partners aims to make a meaningful impact on the lives of individuals seeking to overcome substance abuse challenges.

Founded in 2018, Tausight is a technology company based in Sudbury, Massachusetts with an additional office in San Francisco. It specializes in developing software to reduce healthcare cyber incidents involving patient data theft.

Simon Data develops a customer data platform designed to enhance campaign performance via precise segmentation and personalization. Its platform identifies purchase intent, predicts churn, estimates customer lifetime value, and enables brands to deliver personalized experiences across channels.

Portrait Analytics develops an AI-driven tool designed to assist analysts in accelerating and enhancing investment research. The platform offers features such as Q&A-based search using filings and research, stock chart case studies, stock ideas and recommendations, and qualitative/quantitative screeners.

Sevco Security, Inc., established in 2020 and headquartered in Austin, Texas, specializes in cybersecurity products and services. The company offers a unified asset intelligence platform that addresses the challenges posed by an extended attack surface. This cloud-native platform focuses on cyber asset management and risk management, creating a trusted repository of an organization’s devices, users, and applications. By maintaining a continuously updated inventory that encompasses IT assets, cloud resources, IoT devices, operational technology, and external contractors, Sevco Security enables organizations to autonomously identify and mitigate security gaps. This capability not only helps clients uncover non-compliant assets but also enhances their incident response times, thereby strengthening their overall cybersecurity posture.

Telmai is a data observability platform that focuses on enhancing the quality and integrity of data within modern data environments. The company automates the scanning of complex data stored in data warehouses, data lakes, and event streams to identify anomalies in real time. By leveraging artificial intelligence, Telmai's platform monitors the entire data pipeline, ensuring completeness and correctness by automatically detecting duplicates and other issues. This proactive approach enables data teams to efficiently investigate and address data quality concerns, ultimately helping organizations build secure and scalable data systems.

Laudio LLC is a Boston-based company that offers a software-as-a-service platform focused on healthcare leadership and staff relationship management. Established in 2017, Laudio's platform employs artificial intelligence and predictive analytics to enhance employee engagement and retention while minimizing burnout. It provides healthcare executives and managers with an integrated management system that facilitates timely interactions with staff, digitizes workflows, and suggests proactive interventions based on individual risk factors for turnover. By streamlining processes and improving communication, Laudio aims to help healthcare organizations reduce turnover costs and foster a more engaged workforce.

Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

Portrait Analytics develops an AI-driven tool designed to assist analysts in accelerating and enhancing investment research. The platform offers features such as Q&A-based search using filings and research, stock chart case studies, stock ideas and recommendations, and qualitative/quantitative screeners.

Bobsled is a technology company that simplifies data sharing in the cloud. Its no-code platform automates various aspects of data distribution, ensuring security, version control, access management, and real-time tracking. This streamlined approach enables data teams to focus on strategic tasks rather than manual processes, enhancing efficiency and accuracy across different clouds and platforms.

Retrain.ai is a talent intelligence platform that leverages AI and machine learning algorithms to help organizations develop, upskill, and reskill their employees. It predicts future job roles, maps skills inventories, identifies talent gaps, and recommends personalized training pathways.

Trilio specializes in data protection solutions for Kubernetes, OpenStack, and Red Hat Virtualization environments. Its flagship product, TrilioVault, enables cloud infrastructure operators and developers to recover from disasters, migrate workloads, and move applications between different infrastructures or software distributions.

HYPR is a security technology company focused on providing passwordless authentication solutions. Backed by major investors such as Comcast, Samsung, and Mastercard, HYPR offers a cloud platform that combines the robust security of smart cards with the convenience of smartphones. This platform addresses the challenges of multi-factor authentication by enabling businesses to eliminate customer passwords and streamline login processes, enhancing user experience. Additionally, HYPR's biometric security technology decentralizes authentication, ensuring that personal credentials—such as biometrics, PINs, and passwords—are stored securely on user devices rather than in a centralized system. This approach reduces the risk of enterprise breaches while allowing clients to access information without traditional password barriers.

Oort is an identity threat detection and response platform focused on enhancing enterprise security. Recognizing that over 60% of security breaches involve the abuse of valid identity credentials, Oort positions identity as a critical aspect of cybersecurity. The company offers a Software as a Service (SaaS) platform that allows cybersecurity and IT professionals to efficiently manage their identity and access management (IAM) programs. With a quick deployment process and a focus on reducing identity vulnerabilities at scale, Oort provides organizations with enhanced visibility and control over their identity attack surface. It operates as a fully remote startup based in Boston, MA, and its innovative solutions help clients secure their digital supply chains. Oort is supported by prominent investors and aims to equip security teams with the tools needed to combat identity threats effectively.

InStride Health is an outpatient care platform focused on delivering evidence-based treatment for pediatric anxiety and obsessive-compulsive disorder (OCD). The company offers a tailored virtual care journey that includes individual and group therapy, coaching, and medication management. This comprehensive approach is facilitated by a coordinated team of experienced psychiatrists, therapists, and coaches, ensuring that children and teenagers receive effective and accessible care. InStride Health aims to engage young patients and their families in their treatment, making mental health support both affordable and effective.

ThreatX is a cybersecurity company that specializes in protecting application programming interfaces (APIs) from various threats, including DDoS attacks, bot attacks, and exploitations of vulnerabilities. Its cloud-based platform offers multi-layered detection capabilities that accurately identify malicious actors and dynamically respond to threats, ensuring comprehensive protection for organizations across diverse industries worldwide. By leveraging cloud-optimized infrastructure, ThreatX delivers effective bot management and DDoS mitigation services, enabling businesses to safeguard their networks and effectively manage cybersecurity risks.

Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Abacus Insights, established in 2017 with headquarters in New York City and an additional office in Boston, specializes in developing a cloud-based data integration platform tailored for healthcare companies. This platform organizes and exchanges data from diverse sources and formats, offering maintenance and support services to clients. By standardizing data across the healthcare ecosystem through a secure unified infrastructure, Abacus Insights enables healthcare providers to generate actionable insights, enhance member outcomes, and lower care costs.

Lynx is a fintech healthcare company that focuses on integrating financial solutions with healthcare services. Its API-connected platform facilitates healthcare payments, banking, and e-commerce, allowing businesses to offer tailored health-fintech solutions. By bridging the gap between health and finances, Lynx aims to enhance affordability, drive health engagement, and improve financial security for consumers. The company's technology infrastructure empowers partners to provide a seamless consumer experience, ultimately helping healthcare professionals improve patient outcomes and reduce administrative inefficiencies.

Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

RAD Security is a developer of an AI-driven cloud security platform that focuses on securing AI workloads and cloud infrastructure. Its advanced Cloud Detection and Response (CDR) system continuously monitors the behavior of containerized environments across hybrid-cloud settings. By proactively alerting clients to security issues and automatically addressing suspicious configurations, RAD Security helps organizations maintain compliance and quickly remediate vulnerabilities. The company's platform is designed to provide seamless, scalable protection, allowing businesses to navigate the complexities of AI security with confidence. Through its commitment to proactive security and continuous adaptation, RAD Security supports enterprises as they grow and evolve in an increasingly digital landscape.

Founded in 2018, Promethium develops AI-powered augmented data management software for enterprises. Its solutions enable data analysts to automatically discover, validate, assemble, and access data across multiple repositories using natural language processing and automated data prep. This facilitates self-service analytics, data discovery, data assembly, and DataOps.

Diana Health operates a network of contemporary women’s health practices that collaborate with hospitals to transform maternity and women’s healthcare delivery. The company offers a personalized care platform that integrates clinical services, education, and wellness support, aiming to improve clinical outcomes and streamline operations. Its model places women at the center of decision‑making, empowering them to prepare for childbirth and parenting in a way that aligns with their individual needs and preferences.

Reltio develops cloud-based enterprise data management solutions. It offers a modern data management platform that organizes complex data from various sources into a single, trusted information source. The platform leverages AI to integrate and consolidate data, enabling real-time views, duplicate entity resolution, and data-driven decision-making across industries.

Wayspring is a value-based healthcare organization dedicated to delivering medical, behavioral health, and social support services to individuals with complex needs, particularly those affected by substance use disorders. The company employs a comprehensive and longitudinal model that emphasizes targeted outreach to members, strategic partnerships with providers, and community-based peer support. By focusing on individualized care and ensuring that patients' basic needs—such as access to healthcare, economic stability, and community connections—are met, Wayspring facilitates improved adherence to evidence-based medical practices and enhances health outcomes. This unique approach not only reduces healthcare waste but also empowers patients on their journey to wellness.

Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

ClosedLoop is a healthcare data science platform that enables healthcare organizations to leverage artificial intelligence to enhance patient outcomes and reduce costs. The platform offers an intuitive end-to-end machine learning system, complemented by a library of healthcare-specific features and customizable model templates. By utilizing ClosedLoop's Explainable AI, clients can achieve clinical excellence, operational efficiency, and improved performance in value-based contracts. The company's focus on predictive modeling allows data scientists to create accurate and explainable models tailored to the needs of specific populations. Recognized for its innovation, ClosedLoop has won the CMS AI Health Outcomes Challenge and has been named Best in KLAS for Healthcare AI: Data Science Solutions in both 2022 and 2023. The company is headquartered in Austin, Texas.

Retrain.ai is a talent intelligence platform that leverages AI and machine learning algorithms to help organizations develop, upskill, and reskill their employees. It predicts future job roles, maps skills inventories, identifies talent gaps, and recommends personalized training pathways.

Cortica Inc. is a company dedicated to providing neurological therapies for children facing autism and other neurodevelopmental challenges. Founded in 2014 and based in San Diego, California, Cortica offers tailored treatment programs that are informed by a comprehensive understanding of each child's neurobiology and developmental profile. The company operates multiple centers across California, including locations in Carlsbad, Irvine, San Rafael, Torrance, and Westlake Village. Cortica's services encompass a wide range of assessments and therapies, including diagnoses for autism, ADHD, and developmental delays. Treatment options available include gene sequencing, metabolic testing, electroencephalography, nutrition evaluation, medication management, and various therapeutic interventions such as ABA therapy, parent coaching, speech-language therapy, occupational therapy, physical therapy, and music therapy. The company provides these services through in-home, in-clinic, and telehealth modalities.

ThreatX is a cybersecurity company that specializes in protecting application programming interfaces (APIs) from various threats, including DDoS attacks, bot attacks, and exploitations of vulnerabilities. Its cloud-based platform offers multi-layered detection capabilities that accurately identify malicious actors and dynamically respond to threats, ensuring comprehensive protection for organizations across diverse industries worldwide. By leveraging cloud-optimized infrastructure, ThreatX delivers effective bot management and DDoS mitigation services, enabling businesses to safeguard their networks and effectively manage cybersecurity risks.

Sevco Security, Inc., established in 2020 and headquartered in Austin, Texas, specializes in cybersecurity products and services. The company offers a unified asset intelligence platform that addresses the challenges posed by an extended attack surface. This cloud-native platform focuses on cyber asset management and risk management, creating a trusted repository of an organization’s devices, users, and applications. By maintaining a continuously updated inventory that encompasses IT assets, cloud resources, IoT devices, operational technology, and external contractors, Sevco Security enables organizations to autonomously identify and mitigate security gaps. This capability not only helps clients uncover non-compliant assets but also enhances their incident response times, thereby strengthening their overall cybersecurity posture.

Heartbeat Health, Inc. is a healthcare technology company based in New York that specializes in cardiology services. Founded in 2017, it provides virtual-first solutions for the prevention and management of cardiovascular disease. The company utilizes a data-powered platform to facilitate real-time consultations between patients and physicians, enabling secure communication and collaboration on treatment and dietary advice. By offering tools that allow patients to monitor their heart health, Heartbeat Health aims to reduce cardiovascular risk and the likelihood of adverse health events. Its comprehensive approach enhances patient care and supports at-risk organizations through a focus on higher-value healthcare delivery.

HYPR is a security technology company focused on providing passwordless authentication solutions. Backed by major investors such as Comcast, Samsung, and Mastercard, HYPR offers a cloud platform that combines the robust security of smart cards with the convenience of smartphones. This platform addresses the challenges of multi-factor authentication by enabling businesses to eliminate customer passwords and streamline login processes, enhancing user experience. Additionally, HYPR's biometric security technology decentralizes authentication, ensuring that personal credentials—such as biometrics, PINs, and passwords—are stored securely on user devices rather than in a centralized system. This approach reduces the risk of enterprise breaches while allowing clients to access information without traditional password barriers.

Corvus Insurance Agency, LLC, founded in 2017 and headquartered in Boston, Massachusetts, specializes in providing innovative insurance solutions informed by data-driven underwriting. The company offers its proprietary platform, CrowBar, which enables brokers and policyholders to access policy information, report claims, and receive insights on loss prevention and business intelligence. Corvus emphasizes dynamic loss prevention by delivering tailored recommendations aimed at reducing the total cost of risk for clients. The company has expanded its presence with additional offices in New York, Chicago, Los Angeles, Dallas, and Atlanta, positioning itself as a partner that equips brokers and insurance buyers with the knowledge and tools necessary to navigate complex risks effectively.

Founded in 2018, Tausight is a technology company based in Sudbury, Massachusetts with an additional office in San Francisco. It specializes in developing software to reduce healthcare cyber incidents involving patient data theft.

Founded in 2014, Redox is a Madison, Wisconsin-based company that accelerates healthcare software development and distribution. It offers a full-service integration platform enabling secure and efficient exchange of health data between delivery organizations and technology vendors. Redox aims to improve patient experiences by facilitating seamless interoperability across the healthcare network.

Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

Equip is a virtual program helping families recover from eating disorders at home with comprehensive, gold-standard care created by experts in the field and people in recovery. Equip’s five-person care teams include dieticians, physicians, therapists, and mentors who deliver wrap-around support to provide families progress and lasting recovery. Kristina Saffran and Erin Parks co-founded the company in San Diego, California in 2019.

Hurdle Health, Inc., established in 2020 and based in Washington, D.C., specializes in culturally intentional mental health services. The company operates a digital platform that connects diverse individuals, couples, and families with appropriate therapists, offering a suite of teletherapy services and self-mastery tools. Hurdle's approach is tailored to meet the unique needs of underserved populations, providing culturally responsive care for a wide range of stressors. The platform aims to create a safe and understanding space for patients, focusing on serving the BIPOC community and other minority groups.

ChaosSearch is a data platform company founded in 2017 and headquartered in Boston, Massachusetts, specializing in scalable log analytics. Its innovative platform indexes customer data stored in the cloud, making it fully searchable and facilitating data analytics at scale. By transforming cloud storage into a dynamic analytical database, ChaosSearch enables seamless integration of diverse data streams and streamlines complex data pipelines. The platform supports multiple query languages, including Elastic and SQL, and plans to incorporate machine learning capabilities in the future. This comprehensive approach allows businesses to derive actionable insights from their data while significantly reducing time, cost, and complexity, effectively turning cloud object storage into an efficient analytics engine.

Indico Data Solutions, Inc. specializes in developing enterprise artificial intelligence solutions aimed at automating processes involving unstructured content. Founded in 2013 and based in Boston, Massachusetts, the company offers a platform that enables businesses to create customized machine learning models using smaller datasets. Its tools facilitate the extraction and analysis of information from a variety of non-standard formats, including documents and images. By leveraging deep learning, Indico's platform enhances document-based workflows, addressing applications such as contract analysis, regulatory compliance, customer support automation, and more. This focus on automating labor-intensive tasks allows organizations to efficiently process large volumes of unstructured data and gain meaningful insights.

Trilio specializes in data protection solutions for Kubernetes, OpenStack, and Red Hat Virtualization environments. Its flagship product, TrilioVault, enables cloud infrastructure operators and developers to recover from disasters, migrate workloads, and move applications between different infrastructures or software distributions.

ClosedLoop is a healthcare data science platform that enables healthcare organizations to leverage artificial intelligence to enhance patient outcomes and reduce costs. The platform offers an intuitive end-to-end machine learning system, complemented by a library of healthcare-specific features and customizable model templates. By utilizing ClosedLoop's Explainable AI, clients can achieve clinical excellence, operational efficiency, and improved performance in value-based contracts. The company's focus on predictive modeling allows data scientists to create accurate and explainable models tailored to the needs of specific populations. Recognized for its innovation, ClosedLoop has won the CMS AI Health Outcomes Challenge and has been named Best in KLAS for Healthcare AI: Data Science Solutions in both 2022 and 2023. The company is headquartered in Austin, Texas.

River Search, Inc. is a content discovery platform that enables users to share and engage with stories from across the internet. Established in 2018 and headquartered in New York, the company offers a range of features designed to enhance user interaction, including real-time recommendations based on trending stories, video reaction recording and sharing, and a search tool for accessing breaking news. River Search focuses on creating an environment where users can easily discover and connect with relevant content.

River Search, Inc. is a content discovery platform that enables users to share and engage with stories from across the internet. Established in 2018 and headquartered in New York, the company offers a range of features designed to enhance user interaction, including real-time recommendations based on trending stories, video reaction recording and sharing, and a search tool for accessing breaking news. River Search focuses on creating an environment where users can easily discover and connect with relevant content.

Onapsis specializes in securing business-critical applications and infrastructure. It offers the Onapsis Security Platform, a SAP-certified solution combining preventative, behavioral-based, and context-aware approaches to detect and mitigate security risks. The company serves Global 2000 customers across various industries, including retailers, energy firms, and manufacturers.

MineralTree, Inc. is a Cambridge, Massachusetts-based company that specializes in developing cloud-based accounts payable (AP) and payment automation software. Founded in 2010, MineralTree’s solutions cater to various sectors, including technology, healthcare, consulting, and manufacturing. Its flagship product, Invoice-to-Pay, automates the entire invoice and payment processing workflow, allowing users to extract data from invoices, route them for approval, and execute payments securely from any device. The company also offers FlexPay, which optimizes payment processes with various methods, and SilverGuard, a solution designed to protect against online payment fraud. MineralTree's software integrates seamlessly with popular accounting systems such as Intacct, Microsoft Dynamics GP, NetSuite, and QuickBooks, facilitating improved cash flow management and operational efficiency for businesses, accountants, and banks. The platform is designed to streamline processes for AP managers and finance professionals, delivering cost savings and enhancing control over financial transactions.

Terbium Labs, Inc. is a data intelligence company based in Baltimore, Maryland, established in 2013. It specializes in providing proactive solutions for information security professionals, focusing on the detection and management of data breaches. The company's flagship product, Matchlight, is a comprehensive and fully private dark web monitoring solution that automates the detection of stolen data. It offers fingerprint monitoring, data feeds, and private search capabilities to quickly identify leaks of sensitive information. By alerting organizations when their data appears in unauthorized places on the internet, Terbium Labs enables companies to mitigate risks and protect their high-value information from theft and exploitation.

Retrain.ai is a talent intelligence platform that leverages AI and machine learning algorithms to help organizations develop, upskill, and reskill their employees. It predicts future job roles, maps skills inventories, identifies talent gaps, and recommends personalized training pathways.

Integrated Medical Case Solutions is the provider of work-related trauma prevention and treatment with a proven track record of transforming workers’ compensation cases with notable success in early return-to-work outcomes. Through innovation, best practices and a nationwide network of over 1,000 psychologists and psychiatrists, IMCS provides biopsychosocial assessments to assist patients, employers, and workers’ compensation and disability organizations to optimize chronic pain management and disability claims using an integrated, evidence-based medical approach. IMCS’s early identification and intervention program for high-risk cases has resulted in a 50% savings in many costly and complex workers’ compensation claims.

AristaMD is a digital health company based in La Jolla, California, founded in 2013. It specializes in enhancing the specialty referral process through its eConsult platform. This platform equips primary care providers with clinical workup checklists and enables electronic consultations with specialists. AristaMD's solution allows payers and providers to initiate specialist eConsults using their own specialists or those from AristaMD’s board-certified panel. The platform facilitates the transmission of patient clinical notes, history, lab results, and images, fostering collaboration on care plans within hours. This approach aims to improve patient outcomes by providing timely access to specialty care and reducing referral wait times.

Abacus Insights, established in 2017 with headquarters in New York City and an additional office in Boston, specializes in developing a cloud-based data integration platform tailored for healthcare companies. This platform organizes and exchanges data from diverse sources and formats, offering maintenance and support services to clients. By standardizing data across the healthcare ecosystem through a secure unified infrastructure, Abacus Insights enables healthcare providers to generate actionable insights, enhance member outcomes, and lower care costs.

Sevco Security, Inc., established in 2020 and headquartered in Austin, Texas, specializes in cybersecurity products and services. The company offers a unified asset intelligence platform that addresses the challenges posed by an extended attack surface. This cloud-native platform focuses on cyber asset management and risk management, creating a trusted repository of an organization’s devices, users, and applications. By maintaining a continuously updated inventory that encompasses IT assets, cloud resources, IoT devices, operational technology, and external contractors, Sevco Security enables organizations to autonomously identify and mitigate security gaps. This capability not only helps clients uncover non-compliant assets but also enhances their incident response times, thereby strengthening their overall cybersecurity posture.

Randori Inc., founded in 2018 and headquartered in Waltham, Massachusetts with an additional location in Denver, Colorado, specializes in providing an automated attack platform designed to enhance security programs. The company offers Randori Recon, which helps users identify unknown misconfigurations and process failures, prioritize findings, and reduce attack surfaces by continuously profiling external attack surfaces. Additionally, Randori Attack enables users to test defenses and build resilience by evaluating detection and response capabilities against trusted adversaries. These solutions are utilized in various scenarios, including continuous red teaming, attack surface management, cloud migration, shadow IT risk, and ransomware prevention. Randori serves a diverse range of industries, such as energy, financial services, healthcare, entertainment, and transportation.

Heartbeat Health, Inc. is a healthcare technology company based in New York that specializes in cardiology services. Founded in 2017, it provides virtual-first solutions for the prevention and management of cardiovascular disease. The company utilizes a data-powered platform to facilitate real-time consultations between patients and physicians, enabling secure communication and collaboration on treatment and dietary advice. By offering tools that allow patients to monitor their heart health, Heartbeat Health aims to reduce cardiovascular risk and the likelihood of adverse health events. Its comprehensive approach enhances patient care and supports at-risk organizations through a focus on higher-value healthcare delivery.

Wayspring is a value-based healthcare organization dedicated to delivering medical, behavioral health, and social support services to individuals with complex needs, particularly those affected by substance use disorders. The company employs a comprehensive and longitudinal model that emphasizes targeted outreach to members, strategic partnerships with providers, and community-based peer support. By focusing on individualized care and ensuring that patients' basic needs—such as access to healthcare, economic stability, and community connections—are met, Wayspring facilitates improved adherence to evidence-based medical practices and enhances health outcomes. This unique approach not only reduces healthcare waste but also empowers patients on their journey to wellness.

Iora Health, Inc. is a healthcare organization based in Boston, Massachusetts, that specializes in providing primary care services across the United States. Founded in 2010, Iora Health focuses on redesigning primary care to eliminate barriers and enhance patient experience. Each patient is assigned a personal physician and a health coach, ensuring continuous support and communication through various channels, including email, text, and video, in addition to in-person visits. The company employs a team-based approach to care, which includes a doctor or nurse practitioner, a nurse, a behavioral health specialist, and a health coach, all supported by a proprietary technology platform that integrates population health management into the primary care workflow. Iora Health also offers educational programs, such as group visits, to help patients stay engaged with their health and achieve their wellness goals.

WelbeHealth serves frail seniors through its PACE (Program of All-Inclusive Care for the Elderly) model, providing comprehensive medical and social care. This enables participants to live better, longer, and more independently. The company coordinates various aspects of care, including medical appointments, therapy sessions, transportation, meals, and personal care services.

Founded in 2018, Promethium develops AI-powered augmented data management software for enterprises. Its solutions enable data analysts to automatically discover, validate, assemble, and access data across multiple repositories using natural language processing and automated data prep. This facilitates self-service analytics, data discovery, data assembly, and DataOps.

Bend Financial, Inc. specializes in designing and developing health savings account management solutions. Founded in 2017 and headquartered in Boston, Massachusetts, the company offers a suite of services aimed at enhancing health plan management. As a next-generation provider of health savings accounts, Bend Financial focuses on delivering innovative tools that facilitate better management of health-related expenses for individuals and organizations.

Laudio LLC is a Boston-based company that offers a software-as-a-service platform focused on healthcare leadership and staff relationship management. Established in 2017, Laudio's platform employs artificial intelligence and predictive analytics to enhance employee engagement and retention while minimizing burnout. It provides healthcare executives and managers with an integrated management system that facilitates timely interactions with staff, digitizes workflows, and suggests proactive interventions based on individual risk factors for turnover. By streamlining processes and improving communication, Laudio aims to help healthcare organizations reduce turnover costs and foster a more engaged workforce.

HYPR is a security technology company focused on providing passwordless authentication solutions. Backed by major investors such as Comcast, Samsung, and Mastercard, HYPR offers a cloud platform that combines the robust security of smart cards with the convenience of smartphones. This platform addresses the challenges of multi-factor authentication by enabling businesses to eliminate customer passwords and streamline login processes, enhancing user experience. Additionally, HYPR's biometric security technology decentralizes authentication, ensuring that personal credentials—such as biometrics, PINs, and passwords—are stored securely on user devices rather than in a centralized system. This approach reduces the risk of enterprise breaches while allowing clients to access information without traditional password barriers.

Simon Data develops a customer data platform designed to enhance campaign performance via precise segmentation and personalization. Its platform identifies purchase intent, predicts churn, estimates customer lifetime value, and enables brands to deliver personalized experiences across channels.

Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

GreatHorn, Inc. is a cybersecurity company based in Waltham, Massachusetts, that specializes in protecting cloud communication infrastructure from sophisticated threats such as spear phishing and credential theft. Founded in 2015, GreatHorn offers a range of solutions including Inbound Email Security, which provides automated protection against phishing attacks; Collaboration and Chat Security, designed to help IT and security teams manage their communication security; Continuous Credential Monitoring for real-time threat detection; and Mailbox Protection, which equips users with insights to enhance their email interactions. The company's platform leverages advanced machine learning and anomaly-based threat detection to secure email communications from various types of cyberattacks, including malware and social engineering schemes, thereby enabling clients to maintain secure and efficient operations across multiple cloud platforms.

Edgewise Networks, Inc. is a cybersecurity software provider based in Burlington, Massachusetts, founded in 2016. The company specializes in Trusted Application Networking, focusing on cloud and data center security by preventing network-borne threats. Edgewise’s solutions ensure that only trusted applications communicate over approved network paths, significantly reducing the risk of application compromise. By leveraging machine learning, Edgewise models application communication patterns and generates optimal protection policies, effectively eliminating up to 98% of the network attack surface. This proactive approach allows businesses to secure critical applications without necessitating changes to the existing network infrastructure, thereby enhancing overall security even in scenarios where traditional firewall protections may fail. Edgewise Networks operates as a subsidiary of Zscaler, Inc. as of May 2020.

Abacus Insights, established in 2017 with headquarters in New York City and an additional office in Boston, specializes in developing a cloud-based data integration platform tailored for healthcare companies. This platform organizes and exchanges data from diverse sources and formats, offering maintenance and support services to clients. By standardizing data across the healthcare ecosystem through a secure unified infrastructure, Abacus Insights enables healthcare providers to generate actionable insights, enhance member outcomes, and lower care costs.

Founded in 2014, Redox is a Madison, Wisconsin-based company that accelerates healthcare software development and distribution. It offers a full-service integration platform enabling secure and efficient exchange of health data between delivery organizations and technology vendors. Redox aims to improve patient experiences by facilitating seamless interoperability across the healthcare network.

MineralTree, Inc. is a Cambridge, Massachusetts-based company that specializes in developing cloud-based accounts payable (AP) and payment automation software. Founded in 2010, MineralTree’s solutions cater to various sectors, including technology, healthcare, consulting, and manufacturing. Its flagship product, Invoice-to-Pay, automates the entire invoice and payment processing workflow, allowing users to extract data from invoices, route them for approval, and execute payments securely from any device. The company also offers FlexPay, which optimizes payment processes with various methods, and SilverGuard, a solution designed to protect against online payment fraud. MineralTree's software integrates seamlessly with popular accounting systems such as Intacct, Microsoft Dynamics GP, NetSuite, and QuickBooks, facilitating improved cash flow management and operational efficiency for businesses, accountants, and banks. The platform is designed to streamline processes for AP managers and finance professionals, delivering cost savings and enhancing control over financial transactions.

Better Life Partners Inc. is a healthcare company based in Hanover, New Hampshire, dedicated to providing comprehensive support for individuals struggling with opioid use disorder in the United States. Established in 2018, the company offers a range of services, including medication-assisted treatment, counseling, peer coaching, and group sessions. Better Life Partners focuses on delivering personalized healthcare to vulnerable populations, utilizing technology to create customizable care plans that ensure effective and reliable service delivery. By integrating medical and behavioral healthcare, the company addresses the needs of those affected by addiction, facilitating their recovery through a combination of telehealth, community-based support, and innovative care approaches. With additional offices across New Hampshire, Better Life Partners aims to make a meaningful impact on the lives of individuals seeking to overcome substance abuse challenges.

Corvus Insurance Agency, LLC, founded in 2017 and headquartered in Boston, Massachusetts, specializes in providing innovative insurance solutions informed by data-driven underwriting. The company offers its proprietary platform, CrowBar, which enables brokers and policyholders to access policy information, report claims, and receive insights on loss prevention and business intelligence. Corvus emphasizes dynamic loss prevention by delivering tailored recommendations aimed at reducing the total cost of risk for clients. The company has expanded its presence with additional offices in New York, Chicago, Los Angeles, Dallas, and Atlanta, positioning itself as a partner that equips brokers and insurance buyers with the knowledge and tools necessary to navigate complex risks effectively.

ChaosSearch is a data platform company founded in 2017 and headquartered in Boston, Massachusetts, specializing in scalable log analytics. Its innovative platform indexes customer data stored in the cloud, making it fully searchable and facilitating data analytics at scale. By transforming cloud storage into a dynamic analytical database, ChaosSearch enables seamless integration of diverse data streams and streamlines complex data pipelines. The platform supports multiple query languages, including Elastic and SQL, and plans to incorporate machine learning capabilities in the future. This comprehensive approach allows businesses to derive actionable insights from their data while significantly reducing time, cost, and complexity, effectively turning cloud object storage into an efficient analytics engine.

Randori Inc., founded in 2018 and headquartered in Waltham, Massachusetts with an additional location in Denver, Colorado, specializes in providing an automated attack platform designed to enhance security programs. The company offers Randori Recon, which helps users identify unknown misconfigurations and process failures, prioritize findings, and reduce attack surfaces by continuously profiling external attack surfaces. Additionally, Randori Attack enables users to test defenses and build resilience by evaluating detection and response capabilities against trusted adversaries. These solutions are utilized in various scenarios, including continuous red teaming, attack surface management, cloud migration, shadow IT risk, and ransomware prevention. Randori serves a diverse range of industries, such as energy, financial services, healthcare, entertainment, and transportation.

Founded in 2014, Redox is a Madison, Wisconsin-based company that accelerates healthcare software development and distribution. It offers a full-service integration platform enabling secure and efficient exchange of health data between delivery organizations and technology vendors. Redox aims to improve patient experiences by facilitating seamless interoperability across the healthcare network.

Simon Data develops a customer data platform designed to enhance campaign performance via precise segmentation and personalization. Its platform identifies purchase intent, predicts churn, estimates customer lifetime value, and enables brands to deliver personalized experiences across channels.

Virtudent, Inc. is a Boston-based company established in 2014 that specializes in providing dental services directly to workplaces. The company focuses on delivering basic preventative dental care, including cleanings, X-rays, dental sealants, and fluoride varnish applications. By utilizing a teledentistry platform, Virtudent aims to transform dental healthcare delivery through a scalable model that emphasizes accessibility and patient-centered care. Their mission is to ensure high-quality oral healthcare is seamlessly integrated into the daily lives of employees, making dental services more convenient and effective.

WelbeHealth serves frail seniors through its PACE (Program of All-Inclusive Care for the Elderly) model, providing comprehensive medical and social care. This enables participants to live better, longer, and more independently. The company coordinates various aspects of care, including medical appointments, therapy sessions, transportation, meals, and personal care services.

Reltio develops cloud-based enterprise data management solutions. It offers a modern data management platform that organizes complex data from various sources into a single, trusted information source. The platform leverages AI to integrate and consolidate data, enabling real-time views, duplicate entity resolution, and data-driven decision-making across industries.

Iora Health, Inc. is a healthcare organization based in Boston, Massachusetts, that specializes in providing primary care services across the United States. Founded in 2010, Iora Health focuses on redesigning primary care to eliminate barriers and enhance patient experience. Each patient is assigned a personal physician and a health coach, ensuring continuous support and communication through various channels, including email, text, and video, in addition to in-person visits. The company employs a team-based approach to care, which includes a doctor or nurse practitioner, a nurse, a behavioral health specialist, and a health coach, all supported by a proprietary technology platform that integrates population health management into the primary care workflow. Iora Health also offers educational programs, such as group visits, to help patients stay engaged with their health and achieve their wellness goals.

Gamalon is an artificial intelligence company that develops machine intelligence technologies centered on Bayesian probabilistic programming. Founded in 2013 and based in Boston, the company builds a conversational machine intelligence platform that reads customer text, interprets and summarizes it, and makes predictions to help enterprises understand customer needs and take action. Its technology accelerates machine learning by enabling systems to write and rewrite Bayesian programs and convert streams of text into structured data rows through linking, allowing organizations to train models with limited data while achieving strong accuracy. By extracting insights from customer messages and enabling proactive actions, Gamalon aims to improve customer experiences and support informed decision making.

Wellist operates an online platform that connects patients to local services in the greater Boston area. The company’s platform allows families and patients to find daily support services that range from rides and treatment to meal delivery, home cleaning, acupuncture, and more. Its platform also allows users to build and publish a registry of needed services to share with loved ones, as well as allows them to track activities and thank the loved ones for their support. Wellist was founded in 2013 and is headquartered in Boston, Massachusetts, United States.

Onapsis specializes in securing business-critical applications and infrastructure. It offers the Onapsis Security Platform, a SAP-certified solution combining preventative, behavioral-based, and context-aware approaches to detect and mitigate security risks. The company serves Global 2000 customers across various industries, including retailers, energy firms, and manufacturers.

Nomad Health, Inc. is an online marketplace that connects clinicians with freelance and permanent clinical job opportunities in the United States. Founded in 2015 and based in New York, the company provides a platform where doctors and nurses can search for employment based on various criteria such as location, pay rate, and medical specialty. Nomad Health aims to streamline the healthcare staffing process by replacing traditional methods with a modern, efficient technology platform. The service not only simplifies job searches but also manages digital resumes and credentials, facilitating communication between clinicians and healthcare facilities. This innovative approach addresses the complexities of healthcare staffing, enhancing the experience for both job seekers and providers.

Indico Data Solutions, Inc. specializes in developing enterprise artificial intelligence solutions aimed at automating processes involving unstructured content. Founded in 2013 and based in Boston, Massachusetts, the company offers a platform that enables businesses to create customized machine learning models using smaller datasets. Its tools facilitate the extraction and analysis of information from a variety of non-standard formats, including documents and images. By leveraging deep learning, Indico's platform enhances document-based workflows, addressing applications such as contract analysis, regulatory compliance, customer support automation, and more. This focus on automating labor-intensive tasks allows organizations to efficiently process large volumes of unstructured data and gain meaningful insights.

Pwnie Express is a company specializing in IoT security, focused on closing the security gaps created by the deployment of Internet of Things devices in enterprises. Founded by industry veterans in 2009, it offers a platform that provides comprehensive threat detection for all wired and wireless devices within and around the workplace. The company is unique in its ability to identify rogue, misconfigured, and unauthorized devices across various spectrums, thereby helping businesses prevent potential IoT threats that could disrupt operations. Pwnie Express emphasizes the importance of security assessment and simplifies the process of identifying vulnerabilities through its automated solutions and award-winning sensors, enabling security teams to obtain timely and effective insights into their networks.