Refactor Capital

Remedy Scientific is a pioneering environmental remediation technology firm. It strives to revolutionize how the world combats environmental contamination.

Pioneering a biologically enhanced future for humanity.

Causal Labs provides AI physics models to predict and control the weather.

MIIST Therapeutics focuses on advancing pulmonary drug delivery systems and digital platforms to improve inhaled drug therapies. The company is developing innovative technology aimed at facilitating smoking cessation and addressing the health risks associated with tobacco use. By creating inhaler technology that targets the deepest areas of the lungs, MIIST enables rapid absorption of medications. This approach aims to enhance the effectiveness of inhaled treatments for various health conditions, starting with smoking addiction, and ultimately seeks to reduce the significant health burdens related to tobacco consumption.

General Galactic revolutionize the energy supply chain by producing synthetic hydrocarbons from air and waste CO2 using renewable electricity, making clean fuel affordable and accessible. General Galactic is developing technology to enable democratization of access to critical fuels at the site of need through modular hardware.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

Hexium provides advance energy to medical industries by using isotope enrichment technology.

Pila Energy manufactures renewable energy equipment to power homes and businesses with sustainable solutions.

Bedrock Materials specializes in the development and production of sodium-ion battery materials aimed at enhancing the affordability and efficiency of electric vehicles. By leveraging innovative materials and advanced production techniques, the company enables battery manufacturers to produce these batteries at scale. This approach not only helps to lower the overall costs associated with battery production but also contributes to extending the driving range of electric vehicles. Bedrock Materials is committed to advancing energy storage solutions that support a more sustainable future.

Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing therapies that target senescent cells responsible for various age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of innovative therapeutic candidates. These candidates include novel small molecules designed to selectively address senescent cells, which contribute to the progression of several chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises experienced professionals from the fields of chemistry, technology, and life sciences, bringing a wealth of knowledge in drug development and commercialization.

Orchid is a reproductive technology startup founded in 2019 and headquartered in San Francisco, California. The company specializes in detecting rare genetic disorders through its preconception system, which analyzes the genomes of both partners to assess genetic predispositions to various diseases, including heart disease, Alzheimer’s, and certain types of cancer. Orchid provides a “Couple Report” that incorporates results from an at-home saliva test, allowing couples to understand the potential genetic risks for their future children. If elevated risks are identified, Orchid offers valuable insights to guide couples in monitoring health markers, adjusting their diets, or considering procedures such as in vitro fertilization. The company collaborates with experts in reproductive medicine and genetics to ensure the accuracy of its results.

General Galactic revolutionize the energy supply chain by producing synthetic hydrocarbons from air and waste CO2 using renewable electricity, making clean fuel affordable and accessible. General Galactic is developing technology to enable democratization of access to critical fuels at the site of need through modular hardware.

Hyfé is a feedstock processing company focused on transforming food waste into valuable chemicals, materials, fuels, and foods through fungal fermentation. By upcycling waste generated in food manufacturing, Hyfé aims to create sustainable, cost-competitive products that benefit various industries. This innovative approach not only maximizes profits for food manufacturers but also helps reduce the carbon footprint of the food industry, promoting a more sustainable future. The company is dedicated to unlocking the full value of crops, allowing for the production of essential goods without reliance on petroleum.

Modulo Bio simulates the neuroimmune system to find medication candidates that target microglia cells. The organization's proprietary neuroimmune platform combines the most recent developments in stem cell biology and neuroscience with software, automation, and artificial intelligence to create novel treatments.

Macro Oceans focuses on developing innovative technology that utilizes the restorative properties of seaweed to promote a cleaner, bio-based economy. The company has created a multi-product, zero-waste system aimed at revitalizing ocean ecosystems while offering sustainable alternatives for various industries. By employing a gentle extraction process, Macro Oceans preserves the unique bioactive compounds found in seaweed, resulting in high-quality, all-natural functional ingredients. These ingredients can be used to produce carbon-neutral, fully traceable bioplastics and other environmentally friendly products, enabling businesses to meet sustainability goals and consumer expectations. Through its efforts, Macro Oceans contributes to the restoration of ocean vitality and the advancement of sustainable practices.

Melonfrost is a biotechnology company located in Brooklyn, New York, that focuses on enhancing clinical research through an innovative platform. This platform utilizes machine learning and proprietary artificial intelligence to optimize biological strains by eliminating inefficiencies in the process. By steering the evolution of cells in real-time, Melonfrost enables clients to navigate the biological landscape more effectively. The company integrates advancements in robotics, sensing, fluidics, and environmental control to reduce the reliance on traditional scientific labor, significantly accelerating the development timeline for bioproducts. This approach not only streamlines the research process but also aids clients in bringing their bioproducts to market more efficiently.

Parallel Bio is a biotechnology company focused on transforming the discovery and development of immunotherapies. The company utilizes a platform that integrates advanced human immune organoids with computational techniques to provide valuable insights into human health and disease. By leveraging these innovative tools, Parallel Bio aims to overcome existing barriers in drug development, facilitating quicker pathways to effective treatments for various diseases, including the advancement of immunotherapies, cell therapies, antibody therapies, and vaccines. This approach enhances the ability of medical professionals to understand and address complex health challenges.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

YourChoice Therapeutics, Inc. is a biotechnology company focused on developing non-hormonal contraceptive products for women. Founded in 2018 and headquartered in Berkeley, California, the company has created a technology that employs an active compound to inhibit sperm motility, thereby preventing fertilization of the egg. This innovative approach is based on the concept of a "molecular condom," which aims to provide a contraceptive option that minimizes the risks and side effects associated with traditional hormonal methods. By blocking a specific protein required for sperm fertilization, YourChoice Therapeutics offers a safer and more effective birth control alternative.

FYTO, Inc. is a company based in Cambridge, Massachusetts, that focuses on developing plant-based feed production systems aimed at enhancing the sustainability of agriculture. Founded in 2019, FYTO specializes in creating nutrient-dense crops that require minimal resources, alongside cultivation and harvesting systems designed to ensure quality and consistency. The company's offerings include a variety of agricultural products such as animal feed, plant-based proteins, nutritional supplements, and bio-fertilizers. By adopting climate-friendly practices and methodologies, FYTO aims to support farmers globally in achieving improved economic and environmental outcomes in their agricultural operations.

Ness builds a credit card-first wedge into healthcare. It allows its user to earn rewards for healthy purchases and access exclusive perks to complement their lifestyle. It was established in 2021 and is based in New York, United States.

Evernow is a provider of women's health care services focused on supporting women before, during, and after menopause. The company offers an online teleconsultation platform that connects users with specialized doctors and provides access to science-backed information and treatments. Through this platform, Evernow facilitates conversations about effective care for managing changing hormones, empowering women to lead longer and healthier lives.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

64x Bio develops a platform aimed at accelerating the discovery and optimization of mammalian cell lines for biomanufacturing and therapeutics. The company employs a high-throughput discovery and screening approach combined with an integrated computational design loop to create genetically engineered cell lines tailored for the production of viral vectors. This focus is particularly relevant for cell and gene therapies, as it enhances the efficiency of viral vector production. By providing purpose-built cell lines, 64x Bio enables pharmaceutical and biotechnology companies to improve their manufacturing capacity and reduce costs, ultimately facilitating the timely delivery of innovative therapies to patients.

Phytoform Labs is a biotechnology company focused on revolutionizing plant breeding through advanced gene editing and artificial intelligence technologies. By significantly reducing the time required for developing new crop varieties from decades to years, Phytoform enables breeders to create diverse and resilient plants that maximize yields. Their innovative approach aims to enhance the economics of breeding while ensuring that farmers have access to sustainable crops that improve productivity and minimize environmental impact. Through this integration of cutting-edge technology, Phytoform is positioned to transform agricultural practices and contribute to more efficient food production systems.

Mythic Therapeutics is a biotechnology company dedicated to advancing cancer treatment through innovative antibody-drug conjugates (ADCs). The company specializes in a protein engineering approach that enhances the potency of ADCs while maintaining safety, allowing for more effective targeted therapies across various tumor types. By improving the uptake of these therapeutics in cancerous cells and minimizing payload release in healthy cells, Mythic Therapeutics aims to increase the efficacy of treatments without causing significant side effects or toxicity. This technology positions the company to make a meaningful impact in cancer care, enabling healthcare practitioners to better utilize ADCs for a wide array of patients.

Ophelia Health, Inc. specializes in medication-assisted treatment for individuals struggling with opioid dependence. The company employs a digital platform to facilitate teleconferenced consultations between patients and licensed clinicians, allowing for convenient access to treatment from home. Ophelia provides not only prescription medications but also therapeutic support, aiming to eliminate the stigma often associated with traditional rehabilitation programs. Founded in 2019 and based in Philadelphia, Pennsylvania, Ophelia emphasizes a patient-centered approach that respects individual choices and prioritizes privacy. The organization combines expertise from various fields, including medicine and technology, to deliver evidence-based care and support to those seeking to overcome opioid addiction.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Knowde operates an online marketplace focused on the chemical industry, enhancing the accessibility of trading chemicals, polymers, and industrial ingredients. Its platform utilizes advanced technologies, including deep learning and self-learning data models, to facilitate the search, filtering, sampling, quoting, and purchasing of products tailored to client specifications. By offering a comprehensive chemical taxonomy, Knowde empowers global chemical producers and distributors to transform their operations digitally. This innovative approach allows clients to compare and access products from suppliers worldwide, streamlining the procurement process in the chemical sector. The company has garnered support from prominent investors, highlighting its potential in revolutionizing how chemical transactions are conducted.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Ophelia Health, Inc. specializes in medication-assisted treatment for individuals struggling with opioid dependence. The company employs a digital platform to facilitate teleconferenced consultations between patients and licensed clinicians, allowing for convenient access to treatment from home. Ophelia provides not only prescription medications but also therapeutic support, aiming to eliminate the stigma often associated with traditional rehabilitation programs. Founded in 2019 and based in Philadelphia, Pennsylvania, Ophelia emphasizes a patient-centered approach that respects individual choices and prioritizes privacy. The organization combines expertise from various fields, including medicine and technology, to deliver evidence-based care and support to those seeking to overcome opioid addiction.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

Orchid is a reproductive technology startup founded in 2019 and headquartered in San Francisco, California. The company specializes in detecting rare genetic disorders through its preconception system, which analyzes the genomes of both partners to assess genetic predispositions to various diseases, including heart disease, Alzheimer’s, and certain types of cancer. Orchid provides a “Couple Report” that incorporates results from an at-home saliva test, allowing couples to understand the potential genetic risks for their future children. If elevated risks are identified, Orchid offers valuable insights to guide couples in monitoring health markers, adjusting their diets, or considering procedures such as in vitro fertilization. The company collaborates with experts in reproductive medicine and genetics to ensure the accuracy of its results.

Spora Health, Inc. is a telemedicine provider based in San Francisco, California, established in 2019. The company focuses on delivering primary care specifically designed for people of color, recognizing the importance of lived experiences in shaping health solutions. Spora Health offers treatments across various medical areas, including allergies, cold and flu, infections, digestive issues, musculoskeletal problems, reproductive health, and skin conditions. Its platform utilizes machine learning technology to assess patients' risk profiles and identify chronic conditions such as pre-diabetes, hypertension, and emphysema. This innovative approach facilitates communication between patients and a diverse care team of doctors, nurse practitioners, and nutritionists, enabling individuals to receive effective healthcare advice from convenient locations.

Brave Care, Inc. specializes in urgent pediatric health care services, treating a wide range of conditions, including allergies, asthma, cough, ear pain, eye issues, fever, minor fractures, and rashes. The company also offers pediatric-specific laboratory services, on-site x-ray, and light sedation for certain procedures. Founded in 2019 and based in Portland, Oregon, Brave Care operates clinics exclusively designed for children in Oregon and Texas. In addition to in-person care, the BraveCare.com website and mobile app provide nationwide pediatric advice to assist parents in supporting their children's health and development.

Rubedo Life Sciences, Inc. is a biopharmaceutical company based in Sunnyvale, California, focused on developing therapies that target senescent cells responsible for various age-related diseases. Established in 2018, the company utilizes its proprietary ALEMBIC drug discovery platform to create a pipeline of innovative therapeutic candidates. These candidates include novel small molecules designed to selectively address senescent cells, which contribute to the progression of several chronic conditions, including pulmonary, dermatological, oncological, neurodegenerative, and fibrotic diseases. Rubedo's leadership team comprises experienced professionals from the fields of chemistry, technology, and life sciences, bringing a wealth of knowledge in drug development and commercialization.

64x Bio develops a platform aimed at accelerating the discovery and optimization of mammalian cell lines for biomanufacturing and therapeutics. The company employs a high-throughput discovery and screening approach combined with an integrated computational design loop to create genetically engineered cell lines tailored for the production of viral vectors. This focus is particularly relevant for cell and gene therapies, as it enhances the efficiency of viral vector production. By providing purpose-built cell lines, 64x Bio enables pharmaceutical and biotechnology companies to improve their manufacturing capacity and reduce costs, ultimately facilitating the timely delivery of innovative therapies to patients.

Curative is a healthcare services company founded in 2020 that specializes in providing employer-based health insurance plans with a focus on affordability, engagement, and simplicity. The company aims to make essential healthcare more accessible by offering plans with competitive monthly premiums and no additional costs such as copays or deductibles. Curative's service offerings include COVID-19 testing through self-administered oral fluid swabs, vaccinations, baseline visits, virtual urgent care, and other health services designed to facilitate trusted relationships with providers and care navigators.

ANA Therapeutics Inc. is a biotechnology company focused on the research and development of niclosamide-based vaccines and therapeutics aimed at treating COVID-19. Founded in 2020 and headquartered in Foster City, California, the company is developing a proprietary formulation of niclosamide, which is designed to help medical practitioners effectively treat patients afflicted with the coronavirus. ANA Therapeutics is actively conducting human clinical trials to evaluate the efficacy of its product, ANA001, which comes in the form of capsules. The company's mission is to address the challenges posed by the coronavirus pandemic and contribute to patient care and recovery.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Magic is a technology company that specializes in password-less authentication solutions, providing an alternative login method that enhances security and user experience. Its innovative technology employs a plug-and-play kit combined with blockchain infrastructure, enabling developers to easily integrate customizable password-less login features into their applications. With just a few lines of code, developers can implement this scalable solution, allowing users to access services without traditional passwords, thus streamlining the login process and reducing security risks associated with password management.

Ophelia Health, Inc. specializes in medication-assisted treatment for individuals struggling with opioid dependence. The company employs a digital platform to facilitate teleconferenced consultations between patients and licensed clinicians, allowing for convenient access to treatment from home. Ophelia provides not only prescription medications but also therapeutic support, aiming to eliminate the stigma often associated with traditional rehabilitation programs. Founded in 2019 and based in Philadelphia, Pennsylvania, Ophelia emphasizes a patient-centered approach that respects individual choices and prioritizes privacy. The organization combines expertise from various fields, including medicine and technology, to deliver evidence-based care and support to those seeking to overcome opioid addiction.

Knowde operates an online marketplace focused on the chemical industry, enhancing the accessibility of trading chemicals, polymers, and industrial ingredients. Its platform utilizes advanced technologies, including deep learning and self-learning data models, to facilitate the search, filtering, sampling, quoting, and purchasing of products tailored to client specifications. By offering a comprehensive chemical taxonomy, Knowde empowers global chemical producers and distributors to transform their operations digitally. This innovative approach allows clients to compare and access products from suppliers worldwide, streamlining the procurement process in the chemical sector. The company has garnered support from prominent investors, highlighting its potential in revolutionizing how chemical transactions are conducted.

Red Leader Technologies, founded in 2018 and based in Palo Alto, California, specializes in developing hardware and software solutions for high-definition software-defined lidar systems aimed at 3D mapping. The company’s innovative lidar technology functions as a three-dimensional camera, offering full-depth information and controllable zoom capabilities without relying on beam steering techniques. This advanced system allows for the simultaneous imaging of hundreds of lasers, significantly enhancing image resolution and improving manufacturability while ensuring straightforward integration for clients.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Avail Medsystems, Inc. is a digital healthcare company that develops a platform designed to remotely connect healthcare experts with practitioners. The company's integrated audio/visual hardware and software system facilitates procedural support, observation, and clinical education services, allowing healthcare professionals to collaborate effectively. By enabling real-time access to clinical expertise, Avail aims to eliminate physical, economic, and logistical barriers in the healthcare industry. This approach promotes innovation and enhances the adoption of medical tools and techniques, ultimately improving patient care. Founded in 2017 and based in Palo Alto, California, Avail Medsystems was previously known as Nurep, Inc. and underwent a name change in March 2018.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

Uniform Teeth is an orthodontics practice focused on providing modern and accessible orthodontic care. The company operates dental clinics that specialize in clear teeth aligners, which are crafted from biocompatible, BPA-free plastic designed to fit the patient's teeth at each stage of treatment. By prioritizing quality and intuitiveness in their services, Uniform Teeth aims to simplify the orthodontic experience for patients seeking to straighten their teeth.

Redesign Science is a computational chemistry company focused on advancing early-stage small molecule drug discovery. By utilizing first-principles physics and artificial intelligence, the company simulates protein targets at the atomic level, uncovering subtle drug opportunities that traditional models may overlook. This innovative approach is designed to address emerging challenges in drug discovery, leveraging new scientific insights into biological pathways and disease mechanisms. Redesign Science aims to develop first-in-class small molecules targeting high unmet medical needs, thereby enhancing the efficiency of drug development processes and expanding the potential for therapeutic breakthroughs.

Tempest, Inc. operates an online recovery school that provides a digital program for individuals seeking to quit alcohol and improve their lives. Founded in 2014 and based in New York, the company offers an eight-week virtual course, email courses, and various counseling workshops aimed at addressing alcohol addiction and related mental health challenges. The program emphasizes the significance of purpose, meaning, and creativity in fostering a sober lifestyle. Tempest was previously known as Hip Sobriety, Inc. and rebranded in May 2019. By leveraging its digital platform, Tempest equips participants with the necessary tools and support to navigate their recovery journey and cultivate a healthier, more fulfilling life.

Brave Care, Inc. specializes in urgent pediatric health care services, treating a wide range of conditions, including allergies, asthma, cough, ear pain, eye issues, fever, minor fractures, and rashes. The company also offers pediatric-specific laboratory services, on-site x-ray, and light sedation for certain procedures. Founded in 2019 and based in Portland, Oregon, Brave Care operates clinics exclusively designed for children in Oregon and Texas. In addition to in-person care, the BraveCare.com website and mobile app provide nationwide pediatric advice to assist parents in supporting their children's health and development.

Mori, formerly known as Overlook Research, is a company that develops a natural biopolymer coating designed to extend the shelf life of perishable foods. Founded in 2016 and headquartered in Boston, Massachusetts, Mori's innovative coating is made from proteins extracted from natural silk using salt and water. This protective layer helps slow the spoiling process of various food items, including fruits, vegetables, meat, and seafood, thereby reducing food waste. By focusing on sustainable and economical solutions, Mori aims to transform the food supply and enhance the efficiency of the food, agriculture, and packaging industries.

Umbrella, Inc. is a Brooklyn-based company founded in 1995 that offers home maintenance services through a membership model. The company provides a range of services including home repair, seasonal tasks, and various maintenance needs such as plumbing, electrical updates, and cleaning. Additionally, Umbrella has developed a task management platform designed to connect senior citizens with local workers for small, temporary jobs around the house. This platform facilitates everyday chores and maintenance tasks, such as carpentry, changing light fixtures, fixing leaky faucets, and installing air conditioners. By focusing on these services, Umbrella aims to help seniors maintain their independence and continue living comfortably in their homes.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Kin Euphorics, founded in 2017 and based in New York, specializes in non-alcoholic beverages designed to serve as social tonics. The company offers ready-to-drink products that combine nourishing nootropics, balancing adaptogens, and replenishing botanics. These functional beverages aim to provide a focused relaxation experience by subtly influencing synaptic signaling in the brain, helping to promote relaxation while maintaining cognitive clarity. Kin Euphorics positions its offerings as a sophisticated alternative to traditional alcoholic drinks, allowing customers to enjoy social moments without compromising their well-being.

Vital Software Inc. specializes in cloud-based emergency department software designed to enhance patient experiences and improve operational efficiency in hospitals. Founded in 2017 and based in Atlanta, Georgia, the company utilizes artificial intelligence to streamline workflows, reduce the time clinicians spend on electronic health records, and predict patient admissions hours in advance. This innovative approach not only shortens patient length-of-stay but also provides real-time updates on next steps and estimated wait times, allowing healthcare providers to keep patients and their families informed with minimal additional effort. In addition to its software solutions, Vital offers personalized health plans tailored to individual needs, encompassing doctor consultations, checkups, and pharmacy services, thereby creating a comprehensive health management platform.

Culture Biosciences, Inc. is a biomanufacturing company based in South San Francisco, California, that offers a cloud-based platform for scientists to conduct, monitor, and analyze bioreactor experiments. Founded in 2016, the company focuses on automating bioprocesses to help biotech firms optimize their manufacturing processes and expedite product development. By utilizing robotic sample handling and cloud data monitoring, Culture Biosciences enhances the efficiency of fermentation and bioreactor operations, allowing researchers to achieve results more rapidly than with traditional methods.

AKASA is a leading developer of AI-powered automation solutions tailored for the healthcare revenue cycle. The company focuses on enhancing complex workflows, which allows healthcare providers to improve revenue outcomes and operational efficiency. By automating tasks such as prior authorization and claims processing, AKASA addresses time-consuming challenges that were previously difficult to resolve at scale. Their technology leverages advanced AI and machine learning to streamline revenue cycle management, resulting in significant performance improvements. Clients have reported a 13% reduction in accounts receivable days, an 86% increase in efficiency, and the saving of over 300 hours of staff time each month. With a commitment to data security and measurable results, AKASA has garnered substantial investment to advance its mission of simplifying the financial aspects of healthcare.

Cambridge Cancer Genomics Limited specializes in developing precision oncology solutions that enhance cancer treatment through advanced diagnostics. Founded in 2016 and based in Cambridge, United Kingdom, the company utilizes liquid biopsy and artificial intelligence to create personalized tests that monitor treatment responses in patients. By analyzing circulating tumor DNA from simple blood samples, Cambridge Cancer Genomics enables clinicians to detect relapses earlier than standard methods and predict responses to therapies. This approach allows for timely adjustments to treatment plans, minimizing unnecessary side effects and improving patient outcomes. The company's technology is designed for use by cancer clinics, academic institutions, biotech startups, and pharmaceutical companies, aiming to transform cancer care and optimize therapeutic strategies for patients.

Knowde operates an online marketplace focused on the chemical industry, enhancing the accessibility of trading chemicals, polymers, and industrial ingredients. Its platform utilizes advanced technologies, including deep learning and self-learning data models, to facilitate the search, filtering, sampling, quoting, and purchasing of products tailored to client specifications. By offering a comprehensive chemical taxonomy, Knowde empowers global chemical producers and distributors to transform their operations digitally. This innovative approach allows clients to compare and access products from suppliers worldwide, streamlining the procurement process in the chemical sector. The company has garnered support from prominent investors, highlighting its potential in revolutionizing how chemical transactions are conducted.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Hero is an innovative company that specializes in in-home medication management solutions. Its platform is designed to intuitively sort and dispense medications while offering audible and digital reminders to enhance patient adherence. Hero's technology automates prescription refills and provides both real-time and historical data on medication use, which is crucial for managing chronic conditions. By focusing on improving patient engagement, Hero aims to address the challenges faced by patients and caregivers in medication management, ultimately enhancing health outcomes.

Blockfolio, Inc. is a company that specializes in creating a mobile application for cryptocurrency portfolio tracking and management. Founded in 2014 and based in Marina Del Rey, California, the application allows users to manage their cryptocurrency holdings by providing real-time prices, market data, and news updates. Users can add various cryptocurrencies to their portfolios, receive alerts on market movements, and connect their accounts with exchanges for automated tracking. Blockfolio aims to keep millions of users informed about developments in the cryptocurrency and blockchain industry, while maintaining a commitment to free access for both users and token team partners. As of August 2020, Blockfolio operates as a subsidiary of FTX Trading LTD.

FactoryFour is a software company based in Baltimore, Maryland, founded in 2015, specializing in manufacturing execution systems (MES). Its solutions are designed to manage and automate manufacturing processes, particularly in the realm of digital fabrication, making it a viable service for mass manufacturing. The company's cloud-based software offers highly customizable and user-friendly tools that enhance productivity and profitability by providing real-time data on manufacturing operations. This enables clients to effectively plan production, prioritize orders, and automate scheduling with adaptable logic tailored to their specific needs. By facilitating the capture and analysis of operational data, FactoryFour empowers businesses to improve their manufacturing efficiency and decision-making capabilities.

Checkerspot, Inc. is a biotechnology company based in Berkeley, California, established in 2016. The company specializes in creating performance materials derived from microalgae, focusing on sustainable and high-performance applications. Checkerspot employs advanced techniques in molecular foundry, chemistry, material science, and fabrication technology to develop innovative products, including polyurethanes and textile finish materials. By leveraging the power of biotechnology, Checkerspot aims to expand the range of molecular building blocks available for various industrial applications, providing industries with access to a new generation of sustainable materials.

Shield Bio focuses on combating antibiotic resistance, which is projected to surpass cancer as a leading cause of death by 2050. With infections like gonorrhea becoming resistant to numerous antibiotics, resulting in over 820,000 new cases annually in the U.S., the urgency to address this crisis has escalated. Shield Bio has developed an innovative genomic testing platform that allows sexually transmitted infection (STI) clinics to identify antibiotic-resistant strains of pathogens. This technology enables healthcare providers to determine the most effective antibiotics for treatment, thereby improving patient outcomes and helping to prevent the further spread of antibiotic resistance. By enhancing the accuracy and speed of susceptibility testing, Shield Bio aims to tackle one of the most significant challenges in modern medicine.

Biobot Analytics, Inc. is a wastewater epidemiology company founded in 2017 and based in Cambridge, Massachusetts. The company has developed technology that transforms wastewater infrastructure into public health observatories by analyzing urine and stool samples. This technology provides health data that is independent of hospital reporting systems and is adaptable to emerging public health threats. Biobot Analytics offers a proprietary tool that measures health risks such as infectious disease outbreaks, antibiotic resistance, and drug consumption patterns, including its Opioid Consumption Monitoring Program, which estimates drug use in urban areas through sewage analysis. By generating anonymized public health data, Biobot delivers actionable insights to government officials, enabling them to prioritize interventions and address public health challenges effectively.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

BioRender is a Toronto-based company that develops a science visualization platform tailored for the pharmaceutical and life sciences industries. Founded in 2017, the platform allows scientists to create and share professional scientific figures without the need for drawing skills. BioRender's tool features a comprehensive library of icons and employs a standard visual language to ensure clear communication of scientific concepts. By enabling users to export custom images in various formats, the platform enhances the ability of researchers to effectively showcase their work. The service is designed to save time and reduce costs, ultimately empowering scientists to communicate their findings more efficiently and accessibly.

Uniform Teeth is an orthodontics practice focused on providing modern and accessible orthodontic care. The company operates dental clinics that specialize in clear teeth aligners, which are crafted from biocompatible, BPA-free plastic designed to fit the patient's teeth at each stage of treatment. By prioritizing quality and intuitiveness in their services, Uniform Teeth aims to simplify the orthodontic experience for patients seeking to straighten their teeth.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Solugen, Inc. is a specialty chemicals company based in Houston, Texas, that focuses on producing industrial chemicals through industrial biotechnology and green chemistry. Founded in 2016, Solugen develops a range of environmentally friendly products, including BioPeroxide, a carbon-negative hydrogen peroxide, and BioChelate, a biodegradable chelant. The company also offers ScavSol, a multivalent metal sequestrant for energy applications; ScaleSol, an alternative to phosphonates for scale control; and CorrSol, a corrosion and fouling control product. By utilizing fermentation and enzymatic technology to convert plant sugars into chemicals, Solugen aims to replace petroleum-based products with plant-derived alternatives. Its innovative solutions are designed to benefit various industries, including agriculture, cleaning, energy, and water, while also addressing critical issues such as clean water, sustainable materials, and healthier personal care products.

Octant Bio is a biotechnology company focused on developing synthetic technology aimed at enhancing health and treating diseases. The company employs a platform that integrates synthetic biology, genome engineering, next-generation sequencing, and computational tools to measure the activity of thousands of receptor pathways in human cells. This advanced technology allows scientists to utilize machine learning techniques to engineer small molecules capable of interacting with multiple receptors, thereby creating new possibilities for the treatment of complex diseases.

Enzyme develops a cloud-based platform that assists life sciences companies in navigating FDA approval and regulatory compliance. By automating and simplifying compliance workflows, the platform helps organizations reduce their reliance on expensive consultants, potentially cutting compliance costs by up to 50 percent. Additionally, it addresses the significant personnel burden associated with regulatory issues, which affects about 10 percent of the workforce in biopharma and life sciences, potentially lowering headcount requirements. Enzyme's software not only streamlines compliance monitoring but also ensures adherence to FDA standards, allowing medical device, diagnostic, and drug development businesses to expedite the process of bringing their products to market while minimizing legal risks.

Knowde operates an online marketplace focused on the chemical industry, enhancing the accessibility of trading chemicals, polymers, and industrial ingredients. Its platform utilizes advanced technologies, including deep learning and self-learning data models, to facilitate the search, filtering, sampling, quoting, and purchasing of products tailored to client specifications. By offering a comprehensive chemical taxonomy, Knowde empowers global chemical producers and distributors to transform their operations digitally. This innovative approach allows clients to compare and access products from suppliers worldwide, streamlining the procurement process in the chemical sector. The company has garnered support from prominent investors, highlighting its potential in revolutionizing how chemical transactions are conducted.

Cofactor Genomics is a biotechnology company that specializes in predictive immune modeling and RNA sequencing. By advancing precision medicine, Cofactor aims to address existing barriers in the healthcare sector, transitioning from single-analyte biomarkers to comprehensive multidimensional biomarkers through health expression models. The company operates one of the first CAP-certified clinical RNA sequencing laboratories, which enhances the efficiency and cost-effectiveness of clinical trials for their partners. Cofactor’s expertise encompasses molecular biology, informatics, and database management, allowing them to provide high-quality services tailored to the needs of the healthcare and pharmaceutical industries. Their focus on RNA biomarkers associated with responses to targeted therapeutics supports the commercialization of clinical diagnostic assays for oncologic, immunologic, and neurodegenerative diseases, ultimately contributing to medical research and improved patient outcomes.

Call9, Inc. operates a mobile technology platform designed to connect nursing home patients with emergency physicians for immediate care. Established in 2015 and based in Brooklyn, New York, Call9 offers a tele-EM platform that allows skilled nursing facility (SNF) nurses to activate clinical care specialists when a patient experiences an acute medical event. This platform enables rapid access to board-certified emergency medicine physicians, who provide bedside care and perform necessary point-of-care tests, such as labs and ultrasounds. By facilitating timely interventions, Call9 effectively keeps over 80% of patients in their nursing home beds during emergencies, thereby reducing the need for costly hospital transfers and significantly saving healthcare costs. The company aims to redefine telemedicine standards by ensuring 24/7 access to specialized medical care without the constraints of traditional healthcare facilities.

Gencove is a software platform that focuses on high-throughput and cost-effective genome sequencing through the use of low-pass sequencing technology. The company aims to revolutionize genomics research and diagnostics across various species by providing fast and affordable whole-genome sequencing solutions. Gencove develops both molecular and computational tools that facilitate low-cost genome sequencing, making genomic data accessible to researchers in diverse industries, including agriculture and pharmaceuticals.

Clover Health Inc. is a health insurance company that specializes in providing Medicare Advantage plans primarily for senior citizens. Founded in 2014 and headquartered in San Francisco, California, the company operates in several states, including New Jersey, Arizona, Georgia, Pennsylvania, South Carolina, Tennessee, and Texas. Clover Health utilizes a Preferred Provider Organization (PPO) platform to enhance the quality of life for its members and their healthcare providers. The company employs patient-centered analytics and a dedicated care management team to identify potential health risks and deliver preventive care, thereby aiming to minimize avoidable spending and manage chronic diseases. Its proprietary software platform, Clover Assistant, offers personalized insights to physicians, supporting early detection and effective management of chronic conditions. Clover Health generates the majority of its revenue from its insurance segment, which includes both PPO and HMO plans.

Plutoshift is an operational data platform founded in 2017 and based in Palo Alto, California. The company focuses on empowering operators to automate performance monitoring across various industrial workflows. By leveraging existing data collection systems, Plutoshift enhances data workflows and delivers a unified view of physical infrastructure performance. Its platform aims to drive return on investment for businesses by reducing resource consumption and operating costs. Additionally, Plutoshift facilitates data-driven operations by transferring insights and artificial intelligence from back-office functions to front-line operators, managers, and executives, enabling them to automatically monitor critical processes and access actionable information.

TL Biolabs Corp. is a biotechnology company based in Santa Clara, California, that specializes in automated genomic testing for livestock. Established in 2016, the company focuses on providing cost-effective genomic tests specifically for beef and dairy cattle. In addition to its testing services, TL Biolabs offers complimentary software designed to deliver actionable results, enhancing decision-making for livestock management.

Shield Bio focuses on combating antibiotic resistance, which is projected to surpass cancer as a leading cause of death by 2050. With infections like gonorrhea becoming resistant to numerous antibiotics, resulting in over 820,000 new cases annually in the U.S., the urgency to address this crisis has escalated. Shield Bio has developed an innovative genomic testing platform that allows sexually transmitted infection (STI) clinics to identify antibiotic-resistant strains of pathogens. This technology enables healthcare providers to determine the most effective antibiotics for treatment, thereby improving patient outcomes and helping to prevent the further spread of antibiotic resistance. By enhancing the accuracy and speed of susceptibility testing, Shield Bio aims to tackle one of the most significant challenges in modern medicine.

PathAI, Inc. is a technology company that specializes in developing artificial intelligence solutions for pathology laboratories. Founded in 2016 and headquartered in Boston, Massachusetts, with an additional office in Austin, Texas, PathAI focuses on enhancing the accuracy and efficiency of cancer diagnosis and treatment. The company's platform employs machine and deep learning techniques to analyze large datasets, assisting pathologists in making rapid and precise diagnoses for patients. By addressing complex challenges in pathology, PathAI aims to facilitate personalized medicine and improve patient outcomes by identifying individuals who may benefit from innovative therapies.

Legalist, Inc., founded in 2016 and based in San Francisco, provides data-driven litigation financing services. As an institutional alternative asset management firm, it focuses on helping companies manage legal risks and cover legal expenses. Legalist employs proprietary technology to source and underwrite litigation investments on a non-recourse basis, facilitating access to funding for plaintiffs and their attorneys. This approach enables clients to address legal challenges more effectively while aiming to generate risk-adjusted returns. By leveraging data-backed insights, Legalist aims to transform the way legal financing is approached, making it more efficient and accessible.

Finova Financial LLC, founded in 2015 and based in Palm Beach Gardens, Florida, offers a digital financial services platform that provides affordable loans to consumers based on the equity in their vehicles. Catering to approximately 70 million financially underserved Americans, Finova aims to reduce the high costs associated with traditional lending, offering its Car Equity Line of Credit (C-LOC) at significantly lower rates than the national average. The platform enables clients to access capital quickly, with instant approval decisions and same-day funding available through an online portal. This portal allows users to manage their financial health in real-time, facilitating payments from various devices and at numerous retail locations. Finova’s approach emphasizes building positive relationships with clients, focusing on financial education and support to improve their economic well-being.

Trace Genomics, Inc. is a company focused on advancing soil health and microbiome analysis through artificial intelligence-based diagnostic tools designed for farmers. The company provides a soil microbiome test that utilizes DNA sequencing and a comprehensive database of microbial species to predict soil diseases, assess soil health, and enhance crop quality. By analyzing the microbial composition and diversity within soil samples, Trace Genomics offers valuable insights that empower farmers to make informed decisions regarding soil management, crop selection, and the application of fertilizers. Founded in 2015 and headquartered in Burlingame, California, with an additional office in Ames, Iowa, Trace Genomics aims to support sustainable agricultural practices by providing actionable information that enhances soil productivity and sustainability.

Astranis is a satellite technology developer focused on providing high-speed internet access to underserved regions. The company aims to address the digital divide by launching satellites that can transmit data to specific terrestrial locations, facilitating internet connectivity for the estimated 4 billion people worldwide who currently lack access. By offering reliable internet services at significantly lower costs than traditional methods, Astranis enables governments and businesses to connect communities and expand internet access globally.

Clover Health Inc. is a health insurance company that specializes in providing Medicare Advantage plans primarily for senior citizens. Founded in 2014 and headquartered in San Francisco, California, the company operates in several states, including New Jersey, Arizona, Georgia, Pennsylvania, South Carolina, Tennessee, and Texas. Clover Health utilizes a Preferred Provider Organization (PPO) platform to enhance the quality of life for its members and their healthcare providers. The company employs patient-centered analytics and a dedicated care management team to identify potential health risks and deliver preventive care, thereby aiming to minimize avoidable spending and manage chronic diseases. Its proprietary software platform, Clover Assistant, offers personalized insights to physicians, supporting early detection and effective management of chronic conditions. Clover Health generates the majority of its revenue from its insurance segment, which includes both PPO and HMO plans.

Alloy.ai is a demand and inventory control platform designed to assist consumer goods brands in optimizing their supply chain operations. By providing daily insights at the SKU-store level, Alloy.ai enables brands to swiftly identify and address issues, enhancing their responsiveness to market changes. The platform integrates over 850 pre-built connectors that combine point-of-sale and inventory data with supply chain information, offering comprehensive visibility across networks. This capability allows brands to predict challenges that competitors may overlook. Trusted by a range of companies, from Fortune 500 firms to emerging digital brands, Alloy.ai helps clients achieve significant improvements, including over 35% reductions in out-of-stock situations and notable increases in their bottom line.

Finova Financial LLC, founded in 2015 and based in Palm Beach Gardens, Florida, offers a digital financial services platform that provides affordable loans to consumers based on the equity in their vehicles. Catering to approximately 70 million financially underserved Americans, Finova aims to reduce the high costs associated with traditional lending, offering its Car Equity Line of Credit (C-LOC) at significantly lower rates than the national average. The platform enables clients to access capital quickly, with instant approval decisions and same-day funding available through an online portal. This portal allows users to manage their financial health in real-time, facilitating payments from various devices and at numerous retail locations. Finova’s approach emphasizes building positive relationships with clients, focusing on financial education and support to improve their economic well-being.

Call9, Inc. operates a mobile technology platform designed to connect nursing home patients with emergency physicians for immediate care. Established in 2015 and based in Brooklyn, New York, Call9 offers a tele-EM platform that allows skilled nursing facility (SNF) nurses to activate clinical care specialists when a patient experiences an acute medical event. This platform enables rapid access to board-certified emergency medicine physicians, who provide bedside care and perform necessary point-of-care tests, such as labs and ultrasounds. By facilitating timely interventions, Call9 effectively keeps over 80% of patients in their nursing home beds during emergencies, thereby reducing the need for costly hospital transfers and significantly saving healthcare costs. The company aims to redefine telemedicine standards by ensuring 24/7 access to specialized medical care without the constraints of traditional healthcare facilities.

Verge Genomics is a biotechnology company focused on transforming drug discovery for neurodegenerative diseases through the application of artificial intelligence. Founded by experts in machine learning and seasoned drug developers in neuroscience, the company aims to leverage advances in computational genomics and insights into brain science to identify promising therapeutic targets. Its drug discovery platform utilizes machine learning algorithms to analyze large datasets, enabling the identification of effective drugs and accelerating the development of life-saving treatments. By improving the efficiency of the drug development process, Verge Genomics seeks to enhance patient outcomes and reduce the overall costs associated with pharmaceutical development.

Headspace is a company dedicated to enhancing mental healthcare through its digital platform, which focuses on meditation, mindfulness, and overall mental well-being. The Headspace app features a diverse array of guided meditations led by experts, including its co-founder Andy Puddicombe, aimed at helping users reduce stress, improve focus, and cultivate mindfulness. It also offers specialized tools for sleep, such as "Sleepcasts," soundscapes, and guided sleep meditations, to aid users in achieving better rest. In addition to these features, Headspace provides mindfulness programs that address various aspects of daily life, including work, relationships, and health, while also focusing on managing mental health challenges like anxiety and depression. Furthermore, the company collaborates with organizations through corporate wellness programs, supplying resources designed to enhance employee productivity and well-being.

PicnicHealth is a company focused on simplifying access to medical records and utilizing data to advance medical research. It provides patients with a secure online dashboard that consolidates their medical records from various healthcare providers across the United States. This innovative platform allows individuals to manage their health information efficiently while also giving them the option to contribute their anonymized data for scientific research. By doing so, PicnicHealth enables life sciences researchers to gain insights into real-world disease management and treatment practices, enhancing the understanding of patient experiences beyond traditional clinical trials. The company has successfully assisted tens of thousands of patients and established partnerships with major biopharmaceutical firms, positioning itself as a key player in the evolving healthcare landscape.