Developer of an infrastructure technology designed to manage physical infrastructure assets. The company's technology has vehicle-mounted three-dimensional mapping sensors and a proprietary data processing algorithm to streamline infrastructure inspections, save time, and improve safety, enabling civil engineers and governments to collect data on their roads, sidewalks, signs, and trees which helps in various formats for direct integration into other asset management tools.
Operator of a near-commercial stage company intended to develop non-invasive systems for the treatment of serious neurological disorders. The company's platform is based on neuronal hyperexcitability suppression, they are initially applying their multi-site, precision-targeted neuromodulatory approach to stroke and ALS (amyotrophic lateral sclerosis) and are manufacturing a non-invasive device for the treatment of post-stroke spasticity, and represents a novel, non-invasive targeted-neuromodulation platform to regulate motor neuron excitability, enabling patients to receive treatment without the need for drugs or surgery.
Seaspire Skincare specializes in the development and manufacturing of multifunctional colorants and active ingredients derived from oceanic biodiversity. The company focuses on creating innovative solutions to address chronic and cosmetic hair and skin conditions while aiming to replace harmful components in traditional sunscreens. One of its key products features the biomolecule Xanthochrome, which provides enhanced protection against a wider spectrum of ultraviolet radiation compared to existing physical and chemical filters. This technology is designed for preventative skincare, promoting a healthier approach that minimizes adverse effects on both human and marine health. Through its sustainable and less toxic formulations, Seaspire Skincare contributes to advancing the skincare industry towards safer and environmentally friendly practices.
Aclarity, LLC is a manufacturer of innovative water purification devices aimed at improving water treatment processes for residential use. Founded in 2017 and headquartered in the United States, the company leverages patent-pending electrochemical technology to effectively remove a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. Aclarity's systems are designed to provide cost-effective, low-maintenance solutions, ensuring comprehensive purification while promoting safe and clean water for its customers and end-users.
Concerto Biosciences discovers and develops specific combinations of microbial ensembles. Using kChip, a patented, high-throughput platform that constructs and screens millions of defined microbial communities - Concerto creates massive data sets on how microbes function when growing in complex communities. From these data, Concerto directly discovers microbial ensembles that perform a desired task and learns design rules for ensemble engineering.
Paerpay is a financial application designed to enhance in-person payment experiences for merchants, particularly in the restaurant industry. By streamlining the payment process, Paerpay addresses the challenges faced by merchants, who can lose significant revenue due to payment friction and non-paying customers. The platform allows users to scan a code at their table to either create a new bill or connect to an existing one, facilitating payment, bill splitting, and tipping with ease. This contactless payment service aims to eliminate the frustrations associated with traditional payment methods, enabling a smoother and more efficient transaction experience for both merchants and their customers.
Kytopen Corp. is a biotechnology company based in Cambridge, Massachusetts, focused on advancing cell therapy through its innovative Flowfect technology. Established in 2017, Kytopen specializes in non-viral delivery systems for molecules into challenging immune cells that are typically hard to transfect. The company utilizes a combination of microfluidics and automation to streamline the delivery process, making it faster, more efficient, and cost-effective. By employing a unique platform that integrates continuous fluid flow with electric fields, Kytopen enables researchers to produce high-quality engineered cells in a matter of minutes while preserving their health and functionality. This approach supports the discovery of novel biological insights and the development of affordable cell and gene therapies.
Ascend Elements specializes in the sustainable manufacturing of battery materials by utilizing elements extracted from discarded lithium-ion batteries. The company employs advanced hydro process recycling and direct recycling techniques to deconstruct old cathode materials at the atomic level, facilitating the creation of new cathode materials. This innovative approach allows clients to achieve a favorable return on assets while promoting economically viable recycling and affordable battery materials. Ascend Elements' patented Hydro-to-Cathode™ technology enhances the efficiency of producing new cathode materials from spent lithium-ion cells compared to traditional methods, leading to reduced costs, improved performance, and lower greenhouse gas emissions. Founded in 2015, Ascend Elements is positioned as a leader in transforming battery resource processing and sustainability in the industry.
Kenmei Technologies SL is a Spanish company based in Paterna, founded in 2018 by experts in telecommunications and software. The company specializes in data intelligence through machine-based decision-making, focusing on automating network operations and enhancing customer assurance. Kenmei offers professional services that include network management, technology consulting, and data science and analytics. Its solutions feature autonomous decision-making and network intelligence, which automate the classification, segmentation, and resolution of network issues across various operational levels. By addressing the growing complexity of network environments, Kenmei aims to support operators in efficiently managing their operations.
InstantEye Robotics is a division of Physical Sciences Inc., both located in Andover Massachusetts, approximately a half-hour north of Boston. InstantEye Robotics’ tactical, unmanned aerial systems (UAS) are the systems of choice by the military, law enforcement, first responder, and commercial users around the world. Our products are characterized by their affordability, ruggedness, and ease of use. We provide full-spectrum solutions, from initial concepts through to products manufactured in our state-of-the-art production facility.
Unstack Inc. is a company based in Cambridge, Massachusetts, that specializes in developing a marketing platform tailored for Software as a Service (SaaS) businesses. Founded in 2019, Unstack provides a no-code solution that allows marketers, startups, and teams to create high-performance websites, landing pages, and blogs without requiring technical skills in coding or design. The platform is designed to facilitate the generation of traffic, leads, and sales by enabling users to publish engaging content that enhances their inbound marketing efforts. Unstack aims to streamline the process of website creation and management, making it accessible for users to effectively drive customer engagement and conversion.
Concerto Biosciences discovers and develops specific combinations of microbial ensembles. Using kChip, a patented, high-throughput platform that constructs and screens millions of defined microbial communities - Concerto creates massive data sets on how microbes function when growing in complex communities. From these data, Concerto directly discovers microbial ensembles that perform a desired task and learns design rules for ensemble engineering.
Kytopen Corp. is a biotechnology company based in Cambridge, Massachusetts, focused on advancing cell therapy through its innovative Flowfect technology. Established in 2017, Kytopen specializes in non-viral delivery systems for molecules into challenging immune cells that are typically hard to transfect. The company utilizes a combination of microfluidics and automation to streamline the delivery process, making it faster, more efficient, and cost-effective. By employing a unique platform that integrates continuous fluid flow with electric fields, Kytopen enables researchers to produce high-quality engineered cells in a matter of minutes while preserving their health and functionality. This approach supports the discovery of novel biological insights and the development of affordable cell and gene therapies.
Armored Things Inc. is a Boston-based company that specializes in security management software designed for security agencies. Founded in 2016, it offers the Armored Things Crowd Intelligence Platform, which consolidates data from various sources to enhance operational and security-related decision-making. This platform features analytics, reporting, and visualization tools that provide real-time insights into crowd dynamics and movement within a given space. Additionally, the software automates incident response by connecting with existing devices in venues, such as lights, cameras, locks, and sensors. Armored Things focuses on enhancing safety in large shared environments, including schools, stadiums, and public spaces, by utilizing its predictive incident and emergency response capabilities integrated with IoT and mobile devices.
iVexSol Inc. is a biotechnology company specializing in the development of lentiviral vector (LVV) manufacturing technology aimed at addressing the shortage of these crucial gene delivery vehicles. Established in 2018 and located in Worcester, Massachusetts, iVexSol focuses on streamlining the manufacturing process for cell and gene therapies (CGTs). The company’s innovative technology simplifies the creation of essential reagents, significantly reducing development time and complexity. This advancement not only accelerates the development of CGTs but also enhances access for researchers and manufacturers in the field.
MachineMetrics Inc. develops real-time production monitoring software tailored for manufacturing companies across various industries, including aerospace, automotive, and medical devices. Founded in 2014 and based in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes data from machines. This platform provides live visibility into production processes, enabling workers to respond to manufacturing issues with real-time dashboards and notifications. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics empowers manufacturers to make informed decisions and enhance operational efficiency. The solution boasts an average efficiency improvement of over 20% for its clients, driven by deep manufacturing analytics and artificial intelligence-based predictive notifications.
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
Syrg helps hourly workplaces make operations more efficient, compliant, and human. The company develops a management application platform for employers of hourly work who seek to transform and optimize their workforce. Syrg's technologies integrate with existing HR software with enterprise-grade security, allowing businesses to reduce cost, improve compliance, and increase engagement.
NanoView Biosciences is a biotechnology company based in Boston, Massachusetts, specializing in the characterization of extracellular vesicles, particularly exosomes. Utilizing its proprietary ExoView technology, the company provides high-throughput, cost-effective analysis solutions that facilitate the detection and multiparametric characterization of exosomes from complex biological samples such as whole blood, serum, plasma, and urine. NanoView Biosciences offers a range of products, including the ExoView R100 and ExoView Tetraspanin, as well as custom assays and sample services. The company's innovations support research and the advancement of precision medicine, enabling life science researchers to gain insights into the biological roles of exosomes as potential biomarkers for disease diagnosis, treatment, and monitoring. Founded in 2015, NanoView Biosciences is committed to enhancing the understanding of exosomes in the context of health and disease.
Blue Therapeutics was founded in 2014 by Ajay Yekkirala, David Roberson, Michio Painter and academic founder Phil Portoghese. Blue was born out of the desire to take decades of knowledge and technology from academic research and transform that work into therapeutic solutions that can have positive and lasting impacts for patients in the clinic. Working in New England where the opioid epidemic has struck particularly hard, this meant asking theirselves why better therapeutic options for pain don't exist.
PlenOptika, Inc. is a Massachusetts-based company that develops innovative optical technology to improve eye care accessibility. It manufactures a handheld device called QuickSee, which provides accurate refractive measurements for eyeglass prescriptions at the push of a button. This device is especially beneficial in rural and low-resource settings, addressing the vision needs of over one billion people globally. PlenOptika originated from research initiatives at the Massachusetts Institute of Technology and the Madrid–MIT M+Visión Consortium, where its founders aimed to tackle low vision issues through biomedical innovation. The company has received recognition from social innovation foundations and has collaborated with research centers in the United States, Spain, and India to refine its technology. By reducing the cost and space requirements of traditional autorefractors, PlenOptika enables more efficient and accessible eye care solutions for underserved communities.
SICdrone is an aerospace company based in Portland, Oregon, that specializes in the manufacture of high-speed, high-stability tilt rotor drones designed for commercial applications. Founded in 2016, the company focuses on creating all-weather aerial flight systems capable of conducting structural and energy asset inspections, as well as aerial operations in challenging environments. These drones are engineered for maximum flight efficiency and enhanced mission capabilities, approaching speeds close to the FAA limit of 100 mph. SICdrone has established partnerships with various organizations to support projects in government, security, and agriculture, making it a key player in the drone services sector. The company also offers modular and interchangeable camera systems, facilitating aerial imaging and mapping for defense agencies.
Textician is commercializing a patented breakthrough in machine learning on unstructured text. Called NoNLP(tm) technology, it outperforms both Natural Language Processing (NLP) and Deep Learning in some common use cases. Initial applications are in healthcare IT, specifically ICD-10 coding as a part of RCM applications, delivered either on-premises or via the cloud. In the latter case, no raw PHI is sent to or processed in the cloud, creating a uniquely secure service.
MSW Power Corporation, established in 2012 and based in Acton, Massachusetts, specializes in waste management solutions. The company offers innovative products such as the BWEC GEM, an integrated system that transforms various types of waste—including paper, wood, plastic, agricultural residues, and food—into electricity and heat. Additionally, MSW Power provides the HydroPactor, which efficiently reduces the weight of waste by extracting moisture, and a solid waste destruction system that utilizes mechanical and thermal methods to remove moisture from solid waste. Through these technologies, MSW Power aims to deliver environmentally beneficial and economically viable solutions for energy and waste management.
Realtime Robotics, Inc. specializes in developing motion planning and control processors that empower robots and vehicles to swiftly respond to their surroundings. Founded in 2016 and based in Boston, Massachusetts, the company offers a collision-free motion planning platform that adapts to changes in work environments, allowing for the safe operation of single or multiple robots in unstructured settings. Its RapidPlan processor utilizes advanced computer processing and software to eliminate the trade-off between speed and safety in automation, enabling machines to generate safe motion plans in milliseconds. This innovation facilitates collision avoidance around both static and dynamic objects, while performing various tasks in diverse locations. Realtime Robotics aims to transform automation across industries and enhance the functionality of autonomous vehicles, promoting broader applications and faster adoption of robotics technology.
Pison is a human performance company focused on enhancing cognitive and physiological capabilities through gesture control technology. The company develops a wearable technology that utilizes patented electroneurography to create a gesture-controlled ecosystem. Its advanced biopotential sensor allows for highly sensitive interaction in various applications, including virtual reality, full-body prosthetics, and exoskeletons. By integrating hardware, software, and machine learning, Pison aims to transform human-computer interaction, thereby improving users' quality of life. The company collaborates with notable partners and investors, including Special Forces, the Air Force, and NASA.
Kinto.Care is a provider of an online platform intended to improve communication and provide practical advice for caregivers. The company's platform features user-generated content and digital tools to improve care team collaboration, medication management and check-in data tracking, enabling the family members of a patient to coordinate care and manage medicines through a single platform.
Gencores provides a platform that reduces the risk of concussion with customizable, smart, shock-absorbing helmet inserts.
Flux Marine specializes in developing electric marine propulsion systems designed to enhance performance while minimizing environmental impact. The company focuses on creating electric boat motors that utilize solid-state components to achieve zero emissions, thereby reducing pollution in marine environments. By prioritizing efficiency and sustainability, Flux Marine's motors not only enhance transport capabilities but also significantly lower noise and air pollution. Additionally, these propulsion systems are virtually maintenance-free, contributing to a reduced carbon footprint and promoting cleaner practices within the marine industry.
Verdox is dedicated to reversing climate change through the development and deployment of advanced technology. The company’s proprietary electro-swing process, developed at MIT, enables carbon dioxide and other acid gases to be captured with up to 80% less energy and 70% less cost than conventional approaches.
Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.
Developer of a predictive diagnostic biomarker technology designed to predict patient response to specific chemotherapies. The company's technology specializes in advancing in vitro diagnostics tools and personalized medicine to diagnose and treat cancer and reduce unnecessary suffering, enabling physicians to detect cancerous cells.
14bis Supply Tracking specializes in enhancing supply chain management for the aerospace and defense sectors by mitigating the risks associated with unapproved parts and high administrative costs linked to traditional paper-based documentation. The company offers a platform that leverages blockchain technology and data analytics to ensure transparency and provide immutable lifecycle provenance tracking of assets. This system is designed to integrate seamlessly with various industry ERP platforms and tagging mechanisms, facilitating improved safety and efficiency. Recognized for its innovative approach, 14bis was a finalist in the Privacy/Security category at SXSW 2018, won the Accenture Innovate Award at Web Summit 2017, and was featured at the Paris Air Show 2017.
C-2 Innovations designs and builds all-weather amphibious robots for monitoring, sampling, and mapping various sea-floor terrains. It specializes in areas including; product development, low volume production, business development consulting, contract R&D, and 3-D Animation. C-2 Innovation was founded in 2007 and is based in Shrewsbury, Massachusetts, USA.
Lumme Inc. is a company that specializes in developing an addiction treatment platform that integrates wearable technology, machine learning, and behavioral psychology. Founded in 2014 and based in Amherst, Massachusetts, the platform is designed to function as a personal therapist, providing timely assistance to users. By utilizing sensors on smartphones and smartwatches, Lumme's technology detects, predicts, and prevents behaviors that negatively impact health, specifically targeting addictions to smoking, alcohol, and unhealthy diets. The company's innovative passive gesture recognition technology alleviates the challenges associated with self-monitoring, making it easier for users to manage their behaviors. Lumme Inc. markets its platform to health insurance companies and corporations, aiming to enhance wellness and support addiction recovery.
Giner Electrochemical Systems, LLC (GES) is a subsidiary of Giner, Inc., established May 2000, as an arms-length alliance between Giner, Inc. and General Motors Corporation (GM). GES is an independent business, majority-owned, controlled and operated by Giner, Inc. The alliance with GM allows us to help develop commercially-viable fuel cells for the next generation of transportation and stationary power systems. GES is also focused on the development and commercialization of related electrochemical technologies, including electrolyzers, sensors and capacitors for a range of applications.
Techstyle Materials develops multifunctional construction materials that increase energy efficiency, improve comfort, increase durability, and simplify the construction of buildings. The company was founded in 2018 and is headquartered in Somerville, Massachusetts.
ePaint Company develops specialty antifouling coatings for the United States Coast Guard, The United States Navy, NOAA, Woods Hole Oceanographic Institute, and the U.S Geological Survey. The ongoing research has resulted in three patents.
Students looking to enter the maritime, engineering, emergency management and environmental fields should look into the Massachusetts Maritime Academy in Buzzards Bay, Massachusetts—the second oldest maritime academy in the nation. Unique to the school is its “sea term,” a program conducted in January and February. This program gives aspiring cadets the opportunity to apply their education and training as they sail to ports along the Caribbean Sea. During the approximately 52-day voyage, students will also gain real-world experience in seafaring and ship operations like deck and engine watches, and learn how to properly maintain a vessel. Academics offered at the school include more than five bachelor’s degrees, including Emergency Management, Maritime Engineering, Marine Transportation and more. Two graduate degrees are available in Emergency Management and Facilities Management. The school also offers professional and continuing education courses. In addition to an application, admissions require students to submit official high school transcripts, two letters of recommendation, ACT/SAT test scores and proof of citizenship. Tuition is set lower for Massachusetts residents. Financial aid is determined for students on an individual basis. Students who complete a FAFSA will be considered for financial aid through the form of federal and state grants, loans and institutional scholarships.
Developer of a heat sink optimization platform designed to hybridize computational fluid dynamics. The company develops a compliant vapour chamber technology to eliminate thick thermal interface materials in the form of gap fillers and/or thermal grease in the aforementioned hardware, thereby using analytical, numerical, and experimental methods to consult on complex problems involving momentum, heat and mass transport phenomena.
Inkbit Corporation is a Medford, Massachusetts-based company focused on the research, development, and manufacturing of advanced 3D printers. Founded in 2017, the company has created a next-generation additive manufacturing platform that integrates machine learning and artificial intelligence with material jetting technology. By leveraging the expertise of MIT-trained scientists and engineers in industrial systems, design software, and material science, Inkbit aims to bridge the gap between prototyping and full-scale production. Its platform utilizes machine vision to offer rapid, on-demand manufacturing of multi-material and end-use polymer parts, catering to the needs of demanding industrial applications.
MicroContinuum offers precision micro-and nano-imprinting and patterning using patented roll-to-roll and batch manufacturing technologies. It y serves a range of clients, including Fortune 100 corporations, startups, and government labs, helping test and develop new nanostructured surfaces for the electronics, lighting, solar, energy harvesting, and health industries.
Pendar Technologies is a privately held company focused on developing advanced autonomous chemistry systems that integrate innovative hardware with machine learning algorithms. By leveraging expert knowledge of molecular spectroscopy, Pendar's technology combines a Raman platform with machine learning to quantify chemical reactants, products, and intermediates in real-time. This capability enables the discovery and scaling of new chemical processes, facilitates rapid responses to emergencies, and contributes to life-saving applications.
MachineMetrics Inc. develops real-time production monitoring software tailored for manufacturing companies across various industries, including aerospace, automotive, and medical devices. Founded in 2014 and based in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes data from machines. This platform provides live visibility into production processes, enabling workers to respond to manufacturing issues with real-time dashboards and notifications. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics empowers manufacturers to make informed decisions and enhance operational efficiency. The solution boasts an average efficiency improvement of over 20% for its clients, driven by deep manufacturing analytics and artificial intelligence-based predictive notifications.
Exact Lux builds LED lighting systems using our patent-pending Light Maintenance technology. It eliminates the typical light depreciation of LEDs.
Onvector develops non-chemical water treatment technologies that utilize plasma, advanced oxidation, and disinfection process (AOP) that is more robust than ozone or UV. Its Plasma Vortex technology is a plasma hydrocyclone harnessing the power of arc lightning in a controlled cyclone to destroy the most hard-to-treat contaminants in water and wastewater such as PFAS forever chemicals and other contaminants of emerging concern.
INroof.solar specializes in innovative solar roofing systems that seamlessly integrate solar technology into the architecture of homes. By combining premium roofing materials with a unique solar thermal collection system, INroof.solar transforms the roof into a solar panel, offering a streamlined and aesthetically pleasing appearance. Their Nor’easter solar metal roof panels are specifically designed for cool weather, featuring a smooth coating that facilitates snow shedding and can even heat the roof to melt ice when necessary. In addition to solar hot water and space heating, these panels support radiant floor heating and swimming pool heating, making them a versatile choice for various energy needs. Furthermore, INroof panels are compatible with geothermal heating systems, positioning them as a leading solution for homeowners seeking the benefits of solar energy without the conventional look of traditional solar panels.
Transaera is focused on creating a new generation of affordable and energy-efficient cooling systems designed to minimize energy consumption while providing effective climate control. Their technology aims to enhance indoor environments crucial for both business operations and personal comfort, benefiting human productivity. By offering environmentally friendly cooling solutions, Transaera addresses the need for systems that have a reduced impact on the global climate and local energy infrastructure. These innovative cooling systems are suitable for both residential and commercial applications, enabling consumers to choose options that use significantly less energy compared to traditional air conditioners.
Armored Things Inc. is a Boston-based company that specializes in security management software designed for security agencies. Founded in 2016, it offers the Armored Things Crowd Intelligence Platform, which consolidates data from various sources to enhance operational and security-related decision-making. This platform features analytics, reporting, and visualization tools that provide real-time insights into crowd dynamics and movement within a given space. Additionally, the software automates incident response by connecting with existing devices in venues, such as lights, cameras, locks, and sensors. Armored Things focuses on enhancing safety in large shared environments, including schools, stadiums, and public spaces, by utilizing its predictive incident and emergency response capabilities integrated with IoT and mobile devices.
Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.
Dynamo Micropower Corporation specializes in developing fuel-flexible gas turbines designed for small distributed generation applications in the oil and gas industry. The company's notable products include PowerCore, which provides continuous power for oilfield operations, and Infernocore, a flameless turboheater. Dynamo's innovative turbine-based solutions offer grid-like power quality while significantly reducing energy costs, with the capability to operate on local unrefined gas, achieving savings of up to 80%. The company also delivers custom power solutions tailored to the specific needs of its clients, facilitating plug-and-play installation on flare gas. Dynamo has established a network of distributors and service partners to support its offerings. Founded in 2011 and based in Somerville, Massachusetts, Dynamo has successfully deployed multiple turbines for prominent customers in the industry.
Horsepower Technologies Inc. is a Massachusetts-based company specializing in the manufacture of rehabilitative orthotics for horses. Founded in 2008, the company develops innovative products designed to promote safe movement and expedite recovery for injured horses. One of its key offerings, FastTrack, includes protective padding, a hard shell cuff for structural support, and a mechanism to limit excessive movement of the fetlock joint. By redirecting weight-bearing forces away from injured flexor tendons and ligaments, Horsepower Technologies' orthotics enable horses to engage in moderate exercise during their rehabilitation, thereby enhancing recovery outcomes. The company's products are available for purchase online.
Zylotech is a customer analytics company that specializes in developing a self-learning platform designed to enrich customer profiles, predict purchasing behavior, and deliver relevant recommendations. Founded in 2014 and headquartered in Cambridge, Massachusetts, with additional locations in Sunnyvale, California, and Bengaluru, India, Zylotech offers a comprehensive Customer Data Platform (CDP) that provides B2B organizations with a unified view of their customer data. This enables cross-functional teams to enhance their agility and efficiency. The platform leverages artificial intelligence and machine learning to create a data layer that organizes and standardizes customer profiles, while its analytics layer drives insights throughout the customer journey. Zylotech's Revenue Operations Framework further supports organizations in overcoming silos between marketing, sales, and customer operations, facilitating better alignment among customer-facing teams to adapt to evolving market demands.
Spero Devices, Inc. is a technology company specializing in artificial intelligence and nanotechnology, founded in 2015 and headquartered in Acton, Massachusetts. The company develops and manufactures a CMOS-based co-processor designed to enhance computational efficiency in mobile devices. This hardware accelerator targets edge applications that require real-time processing while adhering to mobile power constraints. Spero Devices focuses on multi-object detection, tracking, and segmentation, transforming edge data into actionable cloud intelligence. By leveraging their innovative hardware and software solutions, the company aims to enable advanced services, including the automated selection of AI training data from edge devices.
Kytopen Corp. is a biotechnology company based in Cambridge, Massachusetts, focused on advancing cell therapy through its innovative Flowfect technology. Established in 2017, Kytopen specializes in non-viral delivery systems for molecules into challenging immune cells that are typically hard to transfect. The company utilizes a combination of microfluidics and automation to streamline the delivery process, making it faster, more efficient, and cost-effective. By employing a unique platform that integrates continuous fluid flow with electric fields, Kytopen enables researchers to produce high-quality engineered cells in a matter of minutes while preserving their health and functionality. This approach supports the discovery of novel biological insights and the development of affordable cell and gene therapies.
Inq-ITS (www.inqits.com) are standards-aligned virtual labs for grades 5-10 science. They improve students' competency at science inquiry practices, and cut teachers' grading time by automatically scoring themselves. They want to help EVERY student learn science inquiry practices and critical thinking, and help empower EVERY educator to exceed new science standards. To be successful in the 21st Century, students need their education to go beyond rote memorization.The virtual science labs we create aim to help students to master the inquiry and critical thinking skills that will help them succeed in the classroom and beyond.
Uniqarta manufactures technologies that accommodate small, ultra-thin ICs and their inclusion within common materials such as paper or plastic. The result is a class of Smart Materials that eliminate the need for RFID label add-ons and accelerate the IoT evolution.
Ascend Elements specializes in the sustainable manufacturing of battery materials by utilizing elements extracted from discarded lithium-ion batteries. The company employs advanced hydro process recycling and direct recycling techniques to deconstruct old cathode materials at the atomic level, facilitating the creation of new cathode materials. This innovative approach allows clients to achieve a favorable return on assets while promoting economically viable recycling and affordable battery materials. Ascend Elements' patented Hydro-to-Cathode™ technology enhances the efficiency of producing new cathode materials from spent lithium-ion cells compared to traditional methods, leading to reduced costs, improved performance, and lower greenhouse gas emissions. Founded in 2015, Ascend Elements is positioned as a leader in transforming battery resource processing and sustainability in the industry.
Fairmarkit is an intelligent sourcing platform that empowers organizations to more efficiently purchase the goods and services they need. By equipping procurement and supply-chain teams with automation and data, Fairmarkit promotes competitive bidding while reducing manual work within existing processes. Leveraged by innovative procurement departments across a number of industries, such as Univision, ServiceNow, and the MBTA, Fairmarkit aims to revolutionize the way organizations make purchases.
ClearGov Inc. develops a Software-as-a-Service-based financial transparency and benchmarking platform for local governments and residents in California, Connecticut, Massachusetts, and New York. Its platform provides information on financial statements into an interactive infographic. The company’s software includes modules for financial forecasting, peer-to-peer financial benchmarking, collaborative government budgeting, public financial transparency, capital projects communications, and department-by-department public accountability. In addition, it offers data analysis tools that allow governments to compare their spending to municipalities of a similar size and demographic makeup. ClearGov Inc. was founded in 2015 and is based in Maynard, Massachusetts.
Veritas Genetics International Ltd. offers genetic testing services aimed at empowering individuals to improve their health and longevity. Based in Danvers, Massachusetts, the company collaborates with scientists, physicians, and patient advocates to develop comprehensive genetic testing solutions. Its advanced genetic technology surpasses traditional next-generation sequencing by detecting a broader range of gene variations. Veritas Genetics also provides a screening test focused on hereditary breast and ovarian cancer risk, facilitating informed decision-making for clinical researchers and healthcare providers. The company operates across North America, Asia, and Europe, striving to enhance the understanding of genetic health.
change:WATER Labs is developing disruptive technologies to expand safe and dignified sanitation to the poor and vulnerable non-sewered household and communities. change:WATER Labs creates a waterless, portable, compact toilet that was built with sustainability and global change in mind. The change:WATER Labs team is dedicated to developing and deploying safer, smarter, more dignified sanitation for communities in need.
Titan Advanced Energy Solutions specializes in developing advanced battery management systems for lithium-ion batteries, leveraging patented ultrasound technology to enhance battery performance. Their flagship product, ionView, delivers over 99% accuracy in state-of-health and state-of-charge assessments, which leads to a minimum 20% increase in charge capacity and a 125% extension of battery life. The systems also offer real-time monitoring, safety controls, and cell-level balancing. Titan's solutions cater to a diverse range of industries, including automotive, energy storage, mobile devices, and battery manufacturing, ultimately supporting the electrification and decarbonization efforts for a sustainable future. Founded in 2016 and located in Somerville, Massachusetts, the company was previously known as Titan Energy Analytics.
Developer of machine-learning software designed to support businesses in building software infrastructure and creation. The company specializes in developing software and API to collect, enrich and stream data from buildings to their digital products and services, enabling engineers to collect commercial building data, which powers their Building Optimization, Cx, RCx, MBCx, and M&V services.
ZwitterCo provides revolutionary membrane solutions for the treatment of highly-impaired wastewater.
Metalmark creates nanostructured materials that destroy submicron scale airborne pollutants and toxins to support healthy indoor air quality. It aims to address the challenges associated with air pollution and climate change. The company's air cleaning technology utilizes catalytic materials to filter the air with nanoscale precision.
It was founded in 2017 and is headquartered in Boston, Massachusetts.
Developer of thermal electric systems intended to deliver clean and low-cost power. The company's electrification system adds an electric boiler in parallel to the existing boiler system and uses dispatching software to manage fuel switching between the boilers without disruption to the supply of steam, enabling industries to offset higher power costs and more emissions-intensive fuels and switch to clean steam energy.
Watchtower Robotics specializes in developing advanced technology for detecting leaks in water distribution systems. Their innovative robot is designed to identify leaks early and accurately, minimizing the risk of water breaks and infrastructure damage. By operating without disrupting water service, the technology allows clients to implement preventative measures before significant leakage occurs. This proactive approach not only helps in preserving water resources but also reduces the potential for costly repairs and downtime associated with water infrastructure failures.
Manus Bio Inc. recreates plant processes in microorganisms to produce natural ingredients through fermentation. The company’s microbial platform converts sugar sources into ingredients with applications, such as flavors, fragrances, food ingredients, cosmetics, vitamins, pharmaceuticals, and agricultural chemicals. It merges metabolic engineering, protein engineering, and systems biology technologies to generate microbes that produce various plant-based ingredients. The company has a strategic partnership with BBGI Public Company Limited. Manus Bio Inc. was formerly known as Manus Biosynthesis, Inc. and changed its name to Manus Bio Inc. in June 2018. The company was founded in 2011 and is based in Cambridge, Massachusetts. It has manufacturing facilities in Cambridge, Massachusetts; and Augusta, Georgia.
Solchroma Technologies, Inc. specializes in the manufacture of full-color, reflective digital display screens designed for advertising applications. Founded in 2015 and headquartered in Somerville, Massachusetts, the company offers non-LED displays that possess sunlight reflective properties and high-quality color reproduction. These displays are particularly suitable for outdoor advertising and on-premise signage. Solchroma's innovative technology features a proprietary system utilizing electroactive polymer actuators, which function as hydraulic pumps to transfer colored ink from reservoirs to color filter chambers. By selectively absorbing ambient light through layered cyan, magenta, and yellow filters, the displays achieve grayscale effects by varying the visible amounts of ink, creating vibrant and dynamic visual presentations ideal for the smart cities of the future.
Developer of radar and arena systems intended to miniaturize radar-sensing and data collection and analysis systems. The company engages in systems capable of scanning through dust, clouds and darkness with high accuracy and has applications in hydrography, oceanography, topography and engineering, thereby providing users with network-based solid-state radar systems for ground and airborne applications.
Physical Sciences Inc. specializes in contract research and development services across various technical domains for both government and commercial clients. The company offers a diverse range of products, including adaptive infrared imaging spectroradiometers, compact adaptive optics retinal imagers, and miniature diode laser-based ambient gas sensors. Additionally, it provides engineering design services and commercial applications in areas such as pharmaceutical process analytical technology, aerospace measurements, and electrochemical engineering solutions. Physical Sciences serves multiple sectors, including aerospace, energy, environment, manufacturing, biomedical, security, and telecommunications, utilizing direct sales, strategic partnerships, and licensing arrangements. Founded in 1973 and headquartered in Andover, Massachusetts, the company operates several satellite offices across the United States, including locations in California, Maryland, Ohio, and New Jersey.
TelAztec is a manufacturer of surface relief microstructures that manipulate light.
Quantum Diamond Technologies, located in Somerville, Massachusetts, is focused on translating advanced quantum science into practical applications. Founded by a team of prominent quantum scientists from Harvard University, the company specializes in the commercialization of nanoscale devices that leverage the principles of quantum mechanics. These innovations enable new possibilities in various fields, including sensing, metrology, and computing. Additionally, Quantum Diamond Technologies is developing an ultrasensitive biomaterial detection and diagnostics platform, further expanding its impact on technology and healthcare.
Horsepower Technologies Inc. is a Massachusetts-based company specializing in the manufacture of rehabilitative orthotics for horses. Founded in 2008, the company develops innovative products designed to promote safe movement and expedite recovery for injured horses. One of its key offerings, FastTrack, includes protective padding, a hard shell cuff for structural support, and a mechanism to limit excessive movement of the fetlock joint. By redirecting weight-bearing forces away from injured flexor tendons and ligaments, Horsepower Technologies' orthotics enable horses to engage in moderate exercise during their rehabilitation, thereby enhancing recovery outcomes. The company's products are available for purchase online.
Spiro Technologies, Inc. is a Boston-based company that develops a relationship management platform designed to assist sales teams across various industries, including construction, finance, manufacturing, professional services, and technology. Founded in 2014, Spiro's platform operates in the background to automate data collection from emails, calls, and texts, eliminating the need for manual data entry. It creates and organizes contacts, prioritizes sales opportunities, and generates intelligent reports to enhance sales performance. Additionally, the platform offers features such as sales suggestions and tools for tracking and managing customer interactions, ultimately enabling businesses to optimize engagement and prevent lost opportunities.
Vata Verks offers non-invasive hi-res water and natural gas data acquisition solution for buildings.
Littoral Power Systems, established in 2015 by experts in the alternative energy sector, focuses on innovative and sustainable hydropower technologies. The company specializes in providing renewable power solutions deployable in remote, non-grid-connected areas. A key feature of Littoral's approach is the development of prefabricated, modular equipment, which simplifies assembly and maintenance, allowing local installation crews with limited resources to effectively implement hydropower systems. The firm produces equipment made from recycled materials, addressing challenges related to cost, environmental impact, and regulatory complexities in ocean energy. Their designs cater to various applications, from small configurations suitable for tight waterways to large energy farms, enabling clients to efficiently harness energy with minimal environmental footprint.
Radial Analytics focuses on addressing significant data challenges in healthcare through its innovative cloud-based planning system. The company's primary product is a decision support solution designed for hospital case managers and discharge planners, enabling them to identify the most appropriate post-acute care facilities for patients. This system utilizes an evidence-driven approach, taking into account each patient's unique clinical, functional, and behavioral needs. By capturing and processing extensive real-time patient data, Radial Analytics helps hospitals optimize the quality of care while reducing post-acute costs for shared-risk patients. The company is partially supported by the National Science Foundation, which aids in the development of technology aimed at creating positive societal and economic impacts.
Radial Analytics focuses on addressing significant data challenges in healthcare through its innovative cloud-based planning system. The company's primary product is a decision support solution designed for hospital case managers and discharge planners, enabling them to identify the most appropriate post-acute care facilities for patients. This system utilizes an evidence-driven approach, taking into account each patient's unique clinical, functional, and behavioral needs. By capturing and processing extensive real-time patient data, Radial Analytics helps hospitals optimize the quality of care while reducing post-acute costs for shared-risk patients. The company is partially supported by the National Science Foundation, which aids in the development of technology aimed at creating positive societal and economic impacts.
ClearGov Inc. develops a Software-as-a-Service-based financial transparency and benchmarking platform for local governments and residents in California, Connecticut, Massachusetts, and New York. Its platform provides information on financial statements into an interactive infographic. The company’s software includes modules for financial forecasting, peer-to-peer financial benchmarking, collaborative government budgeting, public financial transparency, capital projects communications, and department-by-department public accountability. In addition, it offers data analysis tools that allow governments to compare their spending to municipalities of a similar size and demographic makeup. ClearGov Inc. was founded in 2015 and is based in Maynard, Massachusetts.
Infinite Cooling Inc. is a company focused on water recovery systems designed for power plants and other industrial facilities. Founded in 2017 and based in Massachusetts, the company employs innovative technology utilizing high-voltage electric fields to capture and recycle water that evaporates from cooling towers. This process significantly reduces water waste and helps mitigate water scarcity. By implementing its systems, Infinite Cooling enables power plants, data centers, and factories to lower their water consumption and treatment costs, promoting sustainability in industrial operations.
Xilectric develops energy and environmental technologies with a focus on Li-ion technology.
Silverside Detectors Inc. is a technology company. They develop nuclear radiation detection technologies to protect cities and citizens from nuclear terrorism. It designs and develops advanced and adaptable radiation detectors. These detectors can be installed in urban and transit infrastructure for nuclear detection. The company develops inexpensive thermal neutron detectors that can be a building block for large-area networked scanning and other future solutions for nuclear threat reduction. Silverside Detectors Inc was founded by Sarah Haig and Andrew Inglis in 2013; and is headquartered in Boston, Massachusetts.
TACTAI is pioneering the world's first wearable device that enables users to touch and feel virtual objects with life-like realism. The company's patent-pending Dynamic Tactile Wave™ technology creates multi-modal experiences by fully engaging the user's senses and bringing touch, sound, and light together. The company's products help create compelling immersive experiences in Augmented Reality/Virtual Reality applications for gaming, e-commerce, training, film, architecture and education.
Developer of radiofrequency and microwave solutions intended to enhance the performance of mission-critical security, surveillance, and communication systems. The company's products include auto-tuning filters, power electronics cores, ferrite circulators and isolators, ferrite phase shifters, high-power microwave components, and microwave ferrite filters, enabling defense and commercial organizations to design and deploy innovative solutions.
Massachusetts Materials Technologies, founded in 2014 and based in Waltham, Massachusetts, is an MIT spin-off focused on transforming innovative ideas into commercially viable products in materials, mechanics, and manufacturing. The company specializes in nondestructive technologies that measure the strength and toughness of materials, particularly in the oil and gas sector. Its advanced instrumentation allows for the accurate assessment of the mechanical properties of pipelines without disrupting service or requiring pipe cutouts. This capability supports the energy industry in evaluating the integrity of natural gas pipelines, ensuring safety and efficiency in operations.
VocaliD's award-winning technology generates high-quality, natural sounding voices within hours rather than months using cutting-edge machine learning techniques, proprietary voice blending algorithms, and a crowdsourced Voicebank.
Spero Devices, Inc. is a technology company specializing in artificial intelligence and nanotechnology, founded in 2015 and headquartered in Acton, Massachusetts. The company develops and manufactures a CMOS-based co-processor designed to enhance computational efficiency in mobile devices. This hardware accelerator targets edge applications that require real-time processing while adhering to mobile power constraints. Spero Devices focuses on multi-object detection, tracking, and segmentation, transforming edge data into actionable cloud intelligence. By leveraging their innovative hardware and software solutions, the company aims to enable advanced services, including the automated selection of AI training data from edge devices.
Optodot Corporation develops components based on nanotechnology for energy storage, energy conservation, and energy generation markets. It offers NanoPore, a separator that utilizes a patented coating-based manufacturing process to make nano porous ceramic membranes; NPORE lithium ion battery separators; secure infrared coated films and laminates that are used for covert and forensic security applications in various asset security or product/document authentications; and window films. The company focuses on the development of products for lithium ion battery separator and organic solar cell markets; and optical communications, including optical switches, optical buffers, modulators, and photo detectors using optical chip and component technology to enhance optical transport networks. In addition, it provides intellectual property, product development, and contract services in the areas of coatings, as well as focuses on strategic partnerships and licensing to commercialize products for energy, security, and communications solutions. The company serves start-up companies, Global 50 companies, the Department of Defense, and the Department of Energy. It has a strategic partnership with Madico, Inc. The company was founded in 2000 and is based in Woburn, Massachusetts.
MachineMetrics Inc. develops real-time production monitoring software tailored for manufacturing companies across various industries, including aerospace, automotive, and medical devices. Founded in 2014 and based in Northampton, Massachusetts, the company offers an automated cloud solution that collects, analyzes, and visualizes data from machines. This platform provides live visibility into production processes, enabling workers to respond to manufacturing issues with real-time dashboards and notifications. By simplifying the integration of Internet of Things (IoT) technology on the shop floor, MachineMetrics empowers manufacturers to make informed decisions and enhance operational efficiency. The solution boasts an average efficiency improvement of over 20% for its clients, driven by deep manufacturing analytics and artificial intelligence-based predictive notifications.
Applause is a crowd-sourced digital quality testing enabling companies to deliver digital experiences to their customers. Software is at the heart of how all brands engage users, and digital experiences must work flawlessly everywhere. With 300,000+ testers available on-demand around the globe, Applause provides brands with a full suite of testing and feedback capabilities. This approach drastically improves testing coverage, eliminates the limitations of offshoring and traditional QA labs, and speeds time-to-market for websites, mobile apps, IoT, and in-store experiences. Thousands of leading companies — including Ford, Fox, Google, and Dow Jones — rely on Applause as a best practice to deliver high-quality digital experiences that customers love. It was founded in 2007 and is based in Framingham, Massachusetts, United States/
Via Separations, Inc. is a company based in Somerville, Massachusetts, focused on developing membrane-based products for the efficient separation of industrial liquids in complex environments. Incorporated in 2016, the company utilizes advanced materials technology that significantly reduces energy consumption—reportedly using ten times less energy than traditional separation methods. Via Separations specializes in industrial decarbonization through its innovative membrane filtration systems, improving selectivity between nano filtration solutes while enhancing temperature stability, solvent resistance, and oxidizer tolerance. This enables manufacturing facilities to increase productivity while minimizing their energy usage.
Upstream Tech conserving freshwater by powering informed water market transactions.
Heila Technologies is an MIT-born startup dedicated to simplifying the integration and operation of individual Distributed Energy Resources (DERs) and microgrids. It is focused on the commercialization of the Heila IQ Platform, a decentralized optimization system that reduces system complexity and cost. The company was founded in 2017 and is based in Somerville, Massachusetts.
Poly6 Technologies, Inc. offers digital manufacturing solutions to the biotechnology, aerospace, and electronics industry. The company manufactures its products through 3D printing technology. The company develops several stimuli-responsive materials systems that help hardware, software and materials to get integrated into established production processes. Poly6 Technologies, Inc. was incorporated in 2015 and is based in Boston, Massachusetts. As of September 30, 2019, Poly6 Technologies, Inc. operates as a subsidiary of WP CPP Holdings, LLC.
MTPV Power Corporation is a clean energy company based in Austin, Texas, that specializes in Micron-gap ThermalPhotoVoltaics (MTPV) technology. Founded in 2003, the company originated its technology from research at MIT and Draper Laboratory. MTPV Power develops semiconductor chips designed to convert waste heat from various sources into clean energy, primarily electricity. This innovation enables industrial businesses to harness alternative energy sources, thereby enhancing productivity and reducing operational costs. Through its advancements in semiconductor technology, MTPV Power aims to contribute to more sustainable energy solutions in the industrial sector.
NewGrid is a software firm in the utilities industry, focused on the development and commercialization of topology optimization technologies. NewGrid’s software supports power operations and operations planning decision making including outage scheduling and coordination, seasonal contingency planning, remedial action plan and operating guide (Op. Guide) development, and congestion management. Our team is made of engineers, researchers, software developers and economists with years of experience in power systems and markets analysis and design. NewGrid’s founders are thought-leaders in the applications of topology optimization technology to power system operations. With DOE ARPA-E support, they led the first team to ever produce security-constrained topology re-configurations on large-scale RTO systems automatically, with short calculation times acceptable to system operators.