MassVentures

Electrified Thermal Solutions is a company focused on decarbonizing industrial processes by replacing fossil fuels with renewable heat. Founded in 2021 and based in Medford, Massachusetts, the company originated from research conducted at MIT's Department of Nuclear Science and Engineering. Its innovative approach involves developing energy storage technology that converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks. This technology enables various industrial sectors to utilize zero-carbon heat, contributing to a significant reduction in energy consumption's carbon footprint. Through its efforts, Electrified Thermal Solutions aims to facilitate an energy revolution that promotes sustainability in industrial applications.

Adden Energy is a company focused on the development of lithium-metal, solid-state batteries that offer significant advantages for electric vehicles. Their innovative technology is capable of achieving charge times as short as three minutes and maintaining capacity for over 10,000 cycles in lab-scale cells. By advancing solid-state battery technology, Adden Energy aims to facilitate the widespread adoption of electric vehicles globally, thereby playing a crucial role in promoting a cleaner and more sustainable future.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

Theromics Inc. is a biotechnology company focused on developing innovative cell therapies, particularly in the field of thermal ablation for cancer treatment. Founded in 2016 and based in West Bridgewater, Massachusetts, the company has created HeatSYNC Gel, a biopolymer thermal accelerant designed to enhance the effectiveness of microwave and radiofrequency ablation procedures. This gel improves the delivery and absorption of thermal energy in soft tissue and bone, optimizing the ablation zone's shape and volume. By increasing local tissue electrical conductivity, HeatSYNC Gel helps to prevent heat loss due to blood flow, allowing for more precise targeting of tumors and protecting surrounding healthy tissue. The gel can be administered through various methods, including syringe, laparoscope, and bronchoscope, and is intended to improve the overall efficacy of thermal ablation therapies while enabling personalized treatment approaches.

Electrified Thermal Solutions is a company focused on decarbonizing industrial processes by replacing fossil fuels with renewable heat. Founded in 2021 and based in Medford, Massachusetts, the company originated from research conducted at MIT's Department of Nuclear Science and Engineering. Its innovative approach involves developing energy storage technology that converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks. This technology enables various industrial sectors to utilize zero-carbon heat, contributing to a significant reduction in energy consumption's carbon footprint. Through its efforts, Electrified Thermal Solutions aims to facilitate an energy revolution that promotes sustainability in industrial applications.

Versatope Therapeutics is a preclinical-stage biotechnology company specializing in immunotherapy. The company has developed a unique bacterial factory nanoparticle technology that allows for the display of multiple epitopes, addressing the challenges of strain-specific immunity. This innovative approach aims to enhance vaccine potency and improve therapeutic delivery. By enabling the creation of a single vaccine capable of protecting against multiple strains of influenza, Versatope seeks to provide solutions that can significantly advance vaccine development for biotechnology companies.

Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Bloomer Tech, founded in 2015 and based in Cambridge, Massachusetts, is focused on enhancing women's health through innovative technology embedded in everyday clothing, specifically bras. The company develops fabric engineering technology that integrates biometric sensors to monitor vital health metrics, including electrocardiograms, pulse rates, respiratory rates, and heart rhythms. By leveraging machine learning and ordinary fabrics, Bloomer Tech creates a platform for personalized detection, monitoring, and treatment of chronic diseases, particularly those related to cardiovascular health. The collected data is analyzed and made accessible to users, healthcare providers, and medical professionals, fostering real-time healthcare solutions. Through its efforts, Bloomer Tech aims to build a comprehensive dataset on women’s heart health and contribute to addressing global cardiovascular health challenges.

Osmoses specializes in clean membrane technology aimed at decarbonizing gas separations, with a goal of eliminating one gigaton of carbon emissions annually. The company has developed advanced molecular filters that offer exceptional size selectivity, enabling the purification of hydrogen and natural gas. Additionally, these filters facilitate large-scale carbon capture, significantly transforming traditional chemical separation processes. By reducing energy consumption and carbon emissions in industrial operations, Osmoses provides a solution that helps businesses lower costs, minimize product loss, and create value for their clients, contributing to broader efforts in combating climate change.

PhagePro is an early-stage biotechnology therapeutics company focused on developing bacteriophage-based products aimed at preventing bacterial infections, particularly in vulnerable communities worldwide. By offering innovative alternatives for disease prevention, PhagePro seeks to control outbreaks in both clinical and community settings. Its products play a crucial role in addressing public health challenges, helping to prevent fatal diseases such as cholera and enhancing overall health outcomes.

ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.

Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Transcend Air is a company focused on the development and design of aircraft aimed at enhancing private air travel experiences. It specializes in vertical takeoff and landing (VTOL) aircraft, catering to commercial, private, and military sectors. In addition to manufacturing aircraft, Transcend Air operates a short-haul scheduled airline service that connects various cities, offering high-speed travel solutions for both passenger and military cargo transportation.

Guardion specializes in advanced sensor technology aimed at enhancing safety and security through innovative detection systems. The company has developed the world's first radiation detector that leverages the unique quantum properties of nanomaterials, resulting in low-cost, sensitive, and energy-efficient devices suitable for widespread deployment. Guardion's products include analytical instruments and portable chemical and radiation detectors, designed for use in challenging environments across various sectors, including aerospace, medical, and national security. Recognized for its contributions to technology and innovation, Guardion received the MassChallenge 2017 Gold Prize and the Technology in Space Prize from the Center for Advancement in Science in Space and Boeing. In early 2018, the company was selected for the inaugural cohort of the Techstars Autonomous Tech Accelerator, sponsored by the Air Force.

Notch Inc., located in Cambridge, Massachusetts, specializes in developing advanced metamaterial solutions that enhance antenna technology. The company's innovations enable electronically controlled beamforming, which improves communication ranges and performance. Additionally, Notch Inc. incorporates features that bolster cybersecurity, ensuring that their solutions not only optimize connectivity but also protect against potential threats. Through its cutting-edge technology, Notch Inc. aims to address the evolving needs of modern communication systems.

Emvolon is a technology company focused on developing a platform that facilitates the distributed production of chemicals from wasted resources, particularly natural gas at flare sites. By converting this wasted gas into usable chemicals, Emvolon addresses a variety of industrial applications and offers carbon-negative fuel alternatives. The company's innovative approach reimagines conventional diesel engines as miniature chemical reactors, allowing for efficient and localized chemical production. This method eliminates the need for large refineries and chemical plants, making it economically viable for smaller production facilities. Emvolon's technology aims to provide communities with the necessary raw materials while promoting sustainability and reducing waste.

BioSens8 is a developer of advanced biosensors designed to enhance health monitoring and prevent chronic diseases. The company's innovative platform offers real-time, quantitative biosensors that serve various applications. In healthcare, these biosensors assist women in assessing their fertility health, providing crucial information for family planning. In agriculture, BioSens8's technology enables farmers to manage herds effectively and optimize animal reproduction. Additionally, the biosensors can evaluate environmental health, contributing to the revitalization of fragile ecosystems. By catering to the healthcare, agriculture, military, and biomanufacturing sectors, BioSens8 aims to provide efficient solutions for holistic health monitoring.

Ortholevo develops joint injectable therapies that helps to cure tight, restrained joints.

Eyebot is a company focused on revolutionizing eye examination technology to enhance access to vision care. They have developed a freestanding self-service vision testing terminal that allows users to receive accurate eye prescriptions directly at the point of sale. This automated experience aims to reduce barriers to obtaining eye care, making it easier and more efficient for individuals to address their vision needs. By providing ophthalmologists with a proactive tool for eye examinations, Eyebot contributes to improved quality of life for patients while also facilitating cost savings within the healthcare system.

Cyvl.ai is a technology company focused on enhancing the management of physical infrastructure assets for civil engineers and government entities. Utilizing advanced 3D mapping technology and proprietary machine learning algorithms, Cyvl.ai provides a web-based software platform that enables users to efficiently gather and analyze data on various infrastructure elements such as roads, sidewalks, signs, and trees. Their vehicle-mounted mapping sensors streamline the process of infrastructure inspections, ultimately saving time and improving safety. The platform's capability for direct integration with other asset management tools further facilitates effective data utilization, making it a valuable resource for managing infrastructure assets more effectively and affordably.

Stata DX is a company based in Cambridge, Massachusetts, specializing in disease management technology. It has developed an innovative eRapid platform that facilitates at-home patient monitoring through custom biomarker panels for clinical studies. This platform employs a low-cost, affinity-based electrochemical sensing method capable of detecting a wide array of biomarkers in complex biological fluids, particularly liquid MRI for the brain. The technology allows for high sensitivity and selectivity, enabling researchers to gather real-time information about the composition of biological systems using just a single drop of blood.

We develop advanced AI inference technology that consumes only 1/10 the energy of existing solutions, enabling more sustainable and cost-effective artificial intelligence applications

Kytopen is a developer of a cell therapy platform that focuses on the non-viral delivery of molecules into challenging immune cells. The company's innovative technology integrates microfluidics and automation to streamline the delivery process, making it faster, easier, and more cost-effective. Kytopen's automated cell engineering platform enables researchers to produce healthy and functional engineered cells rapidly, maintaining their health and functionality. By combining continuous fluid flow with electric fields, Kytopen enhances the efficiency of payload delivery to primary cells, supporting advancements in biology and paving the way for innovative cell and gene therapies.

Feon develops new-molecule-based liquid electrolytes for lithium-ion and lithium-metal batteries.

River Otter Renewables is a recycling comany that produced biocrude oil from plant and waste as well as sewage and plastic waste.

Active Surfaces is commercializing MIT-developed ultra-thin-film solar technology. The company seeks to revolutionize the conventional energy sector by making solar power widespread and seamlessly integrating it into everyday materials. Its innovative manufacturing approach significantly reduces production expenses, presenting a transformational opportunity for semiconductor and electronics manufacturing.

A small school where you can actually get to know your professors and other students, Western New England University offers undergraduate and graduate academics, being particularly well known for its Pharmacy and Engineering programs. Western New England University is located in Springfield, Massachusetts, a small city about two hours from Boston and only 30 minutes from the beautiful Berkshire Mountains. Undergraduate programs at Western New England University are offered through the Arts and Sciences, Business and Engineering departments. There is also a Pre-Pharmacy major from which many students move into the graduate Pharmaceutical Sciences program, one of Western New England College’s strongest. Other graduate degrees are awarded in Law, Engineering and Business. Since Western New England is a small school, students have the chance to get to know one another through the numerous on-campus events. Traditional festivals are a big part of student life and include a Music Fest, and fall, winter and spring festivals. There are also performing arts groups, including a drama club, choir, and a school newspaper and other literary publications. There are also weekly campus parties and field trips throughout the Northeast. While students applying to the graduate programs will have to meet department-specific requirements, all undergraduate applicants submit the same materials, such as transcripts and an essay, regardless of their preferred major. Students may also apply for scholarships and other forms of financial aid to help with tuition costs.

Dottir Labs is a spectroscopy sensor technology that detects nutrients, metabolic markers, and organic and non-organic waste products.

Benchmark Labs, based in San Francisco, California, specializes in AI-driven weather forecasting tailored for the agricultural sector and other industries. The company delivers precise, asset-specific forecasts that help clients navigate the challenges posed by changing weather patterns. By utilizing Internet of Things (IoT) sensors from various manufacturers, Benchmark Labs provides critical data that enables organizations to optimize renewable energy generation and manage water allocation effectively. The accuracy of their forecasts is essential for maintaining infrastructure and operational efficiency in the face of increasing weather variability.

Adhesion Technologies is a bio-adhesive producer offers an alternative to toxic furniture glues, promoting to reduce chemical exposure.

Blaze Power operates as a lithium-ion battery materials manufacturer. It innovates and commercializes iron-based cathode materials to enable mass-market electrification in transportation and energy storage. The company is driven to industrialize these cathodes in purpose-built inflation reduction act-compliant facilities.

ThermoBionics specializes in the production of wearable cooling goods that leverage innovative technology to enhance cooling efficiency while reducing weight. The company's proprietary, patent-pending technology effectively manages the body's thermoregulatory functions, allowing users to minimize sweating and facilitate moisture evaporation, regardless of external temperature and humidity conditions. This advancement provides a practical solution for individuals seeking comfort in varying environmental conditions.

MacroCycle is developing a technology to curb the usage of fossil fuel derived plastic through a circular, sustainable and zero-carbon plastic upcycling process. The company's proprietary process based on the synthesis of cyclic macromolecules enables us to produce virgin-grade recycled PET from plastic waste at lower energy use than traditional processes.

WPI has a lot to offer - extraordinary students, world-renowned faculty members at the top of their fields, state-of-the-art research facilities, and a community teeming with activity. You have a lot to offer too - you're ambitious, you want to be challenged, you want to succeed, and you want to make a difference in the world. You know where you want to go; WPI can help you get there.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Aclarity, LLC is a cleantech startup established in 2017 and based in the United States. The company specializes in manufacturing and marketing advanced water purification devices designed for residential use. Aclarity's systems utilize innovative electrochemical technology to effectively eliminate a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. These devices provide customers with cost-effective and low-maintenance solutions for comprehensive water treatment, addressing the pressing need for clean water in homes and contributing to broader environmental sustainability efforts.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

Emvolon is a technology company focused on developing a platform that facilitates the distributed production of chemicals from wasted resources, particularly natural gas at flare sites. By converting this wasted gas into usable chemicals, Emvolon addresses a variety of industrial applications and offers carbon-negative fuel alternatives. The company's innovative approach reimagines conventional diesel engines as miniature chemical reactors, allowing for efficient and localized chemical production. This method eliminates the need for large refineries and chemical plants, making it economically viable for smaller production facilities. Emvolon's technology aims to provide communities with the necessary raw materials while promoting sustainability and reducing waste.

Florrent is a bio-based materials and energy storage company focused on addressing key challenges in global decarbonization and the electrification of transportation and buildings. It specializes in the development of energy-density ultracapacitors made from sustainable hemp biomass sourced from a network of BIPOC farmers. These ultracapacitors enhance the stability of electrical grids and facilitate the integration of renewable energy sources, electric vehicles, and net-zero buildings. By enabling communities to locally generate, store, and utilize renewable power, Florrent contributes to the transition towards a resilient, renewable, and equitable energy economy.

ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.

Southie Autonomy is a Boston-based company founded in 2017 that specializes in developing robot software allowing industrial robots to be easily re-purposed and re-deployed by individuals without robotics expertise or technical skills. The company's automation system facilitates quick setup and execution of new robotic tasks, making it feasible for businesses to justify the use of automation in a wider range of applications, such as kitting, palletizing, and simple assembly. By lowering the time, cost, and skill barriers associated with robotic automation, Southie Autonomy aims to help businesses achieve a faster return on investment.

Phoenix Tailings Inc. is a Massachusetts-based company that focuses on the recycling and re-mining of mining tailings and hazardous by-products, such as Bauxite Residue, to produce essential metal products. Founded in 2019, the company aims to extract strategic materials critical to various industries, including aerospace, defense, automotive, biotechnology, and electronics. By treating mining and refining waste as new ore, Phoenix Tailings provides an innovative solution to eliminate hazardous environmental waste while creating primary metals sustainably and economically. This approach not only addresses the demand for metals in multiple sectors but also promotes environmentally friendly practices by offering carbon-free alternatives.

Fourier is a thermal management solutions ranging from high power density electronics to renewable energy to space applications.

Rendever is a company focused on addressing social isolation among seniors through virtual reality experiences. Its platform is utilized in senior living communities and healthcare settings to alleviate feelings of depression and loneliness by promoting personal connections. Participants can engage in group sessions to fulfill bucket list items, revisit significant locations, and share stories, thereby enhancing their emotional well-being. Rendever collaborates with notable senior living operators and healthcare systems, and its initiatives are supported by research from organizations such as the NIH and NIA. The company also has commercial partnerships with prominent entities, including AARP and Verizon, to expand its reach and impact.

Notch Inc., located in Cambridge, Massachusetts, specializes in developing advanced metamaterial solutions that enhance antenna technology. The company's innovations enable electronically controlled beamforming, which improves communication ranges and performance. Additionally, Notch Inc. incorporates features that bolster cybersecurity, ensuring that their solutions not only optimize connectivity but also protect against potential threats. Through its cutting-edge technology, Notch Inc. aims to address the evolving needs of modern communication systems.

Feon develops new-molecule-based liquid electrolytes for lithium-ion and lithium-metal batteries.

AmberGen, Inc. is a privately-held company based in the Boston area, established in 1995 to commercialize innovative photonic technology originally developed at Boston University. The company focuses on advancing therapeutics and diagnostics by addressing significant challenges in medicine. AmberGen employs patented techniques in proteomics and utilizes light-based control of biomolecules to create photocleavable linkers and protein engineering reagents. Its services encompass drug discovery, the development of high-throughput multiplex immuno-diagnostic assays, and mass spectrometric imaging for advanced tissue and array scanning. These innovations enable medical practitioners to detect diseases at earlier stages, thereby enhancing diagnostic capabilities and improving patient outcomes.

Reveal Pharmaceuticals focuses on developing innovative MRI contrast agents that provide a gadolinium-free alternative to existing gadolinium-based contrast agents (GBCAs). The company aims to enhance medical imaging safety for all patients, particularly those at risk from gadolinium exposure. Its pipeline includes precision imaging agents designed to assist in the diagnosis and treatment of conditions such as pulmonary embolism and cancer. By integrating its patented gadolinium-free RVP platform with targeted molecular probes, Reveal Pharmaceuticals enables healthcare professionals to conduct safer scans without the need for biopsies, thereby supporting the advancement of targeted therapeutics and personalized medicine.

Kanda Industries designs and manufactures the custom furnitures for homes and Offices.

Irradiant Technologies, founded in 2020 and based in Cambridge, Massachusetts, specializes in advanced nanofabrication utilizing implosion fabrication lithography. The company focuses on developing a platform that facilitates the ultrafast three-dimensional assembly of mixed materials, such as conductors, semiconductors, dielectrics, proteins, and DNA, with nanoscale precision and gradient control. This innovative approach enables the creation of novel photonic and optical components, providing light-based alternatives for applications in telecommunications, computation, and sensing.

Advanced Silicon Group is a nanotechnology company established in 2015, focused on commercializing innovative silicon nanotechnology developed by its employees. The company specializes in measuring host cell proteins in biomanufacturing, offering a range of technologies that include photovoltaics, lithium-ion batteries, microfluidics, and micro-electromechanical systems (MEMS). By leveraging silicon nanowire arrays, Advanced Silicon Group aims to enhance the performance of its clients' products while reducing costs, particularly through the development of next-generation biosensors that enable the simultaneous measurement of multiple protein concentrations.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Haystack Ag supports growers and global carbon markets with tools for high-accuracy, cost-effective soil carbon measurement.

Seia Bio is a biotechnology research company that specilizes in producing non-model microbes.

AI platform producing compostable and biodegradable plastic alternatives

Northeastern University is an experiential and research institution located in Boston, Massachusetts, established in 1898. It offers a wide range of undergraduate and graduate programs, including doctorate degrees across nine colleges and schools. In addition to its primary campus in Boston, Northeastern has graduate campuses in Charlotte, North Carolina, and Seattle, providing advanced degrees tailored to various professional fields. The university emphasizes experiential learning and research, preparing students for successful careers while contributing to scholarly and public service initiatives.

Aclarity, LLC is a cleantech startup established in 2017 and based in the United States. The company specializes in manufacturing and marketing advanced water purification devices designed for residential use. Aclarity's systems utilize innovative electrochemical technology to effectively eliminate a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. These devices provide customers with cost-effective and low-maintenance solutions for comprehensive water treatment, addressing the pressing need for clean water in homes and contributing to broader environmental sustainability efforts.

Osmoses specializes in clean membrane technology aimed at decarbonizing gas separations, with a goal of eliminating one gigaton of carbon emissions annually. The company has developed advanced molecular filters that offer exceptional size selectivity, enabling the purification of hydrogen and natural gas. Additionally, these filters facilitate large-scale carbon capture, significantly transforming traditional chemical separation processes. By reducing energy consumption and carbon emissions in industrial operations, Osmoses provides a solution that helps businesses lower costs, minimize product loss, and create value for their clients, contributing to broader efforts in combating climate change.

Stitch3D is a cloud platform designed for hosting, viewing, analyzing, and sharing 3D files. The company focuses on streamlining the process of translating complex spatial data into actionable insights, significantly reducing the time required for such tasks. By utilizing artificial intelligence and machine learning algorithms, Stitch3D enables differential analysis, feature extraction, geometric search, and predictive maintenance. This technology allows enterprises to collect, aggregate, and manage 3D data in a more simplified and accessible manner.

Gel4Med LLC is a Boston-based medical technology company established in 2015, specializing in the development of innovative biomaterials for tissue treatment and regeneration. The company focuses on creating an antimicrobial tissue-scaffolding matrix designed to eliminate antibiotic-resistant bacteria while promoting tissue regeneration. By utilizing bioinspired and engineered materials, Gel4Med aims to address significant healthcare challenges, particularly in wound care. Their leading technology employs a self-assembling peptide mechanism that acts as both an antibacterial barrier and a promoter of tissue regeneration, thus enhancing patient outcomes and preventing infections during surgical procedures.

Loop CO2 is a company focused on developing innovative technology that transforms carbon dioxide into essential products, contributing to a sustainable future. By converting CO2 into items such as cosmetic oils, adhesives, and thermoplastic elastomers, Loop CO2 enables its customers to minimize their environmental impact through the use of eco-friendly alternatives. The company's solutions aim to address climate challenges while promoting the utilization of carbon emissions in a productive manner.

Z-Polymers is a clean-tech materials science company based in Lowell, Massachusetts, founded in 2021. It focuses on developing innovative polymer materials, particularly thin fiber polymers, to address fundamental challenges in mission-critical industries. The company's applications span areas such as 3D printing and the hydrogen economy, where it strives to enhance sustainability and environmental safety by replacing toxic substances with eco-friendly alternatives. Through its advanced polymer science, Z-Polymers aims to contribute to the development of sustainable solutions that support various industrial needs.

PathMaker Neurosystems is a neurotechnology company focused on developing non-invasive treatments for serious neurological disorders, particularly neuromotor conditions. The company is advancing a platform that employs neuronal hyperexcitability suppression, utilizing a multi-site, precision-targeted neuromodulatory approach. Initially, PathMaker is applying this innovative technology to address issues related to stroke and amyotrophic lateral sclerosis (ALS). They are in the process of manufacturing a non-invasive device specifically designed to treat post-stroke spasticity. This novel approach enables the regulation of motor neuron excitability, allowing patients to receive effective treatment without the need for drugs or surgery.

Electrified Thermal Solutions is a company focused on decarbonizing industrial processes by replacing fossil fuels with renewable heat. Founded in 2021 and based in Medford, Massachusetts, the company originated from research conducted at MIT's Department of Nuclear Science and Engineering. Its innovative approach involves developing energy storage technology that converts intermittent renewable electricity into constant heat using low-cost conductive ceramic blocks. This technology enables various industrial sectors to utilize zero-carbon heat, contributing to a significant reduction in energy consumption's carbon footprint. Through its efforts, Electrified Thermal Solutions aims to facilitate an energy revolution that promotes sustainability in industrial applications.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

Eden is focused on developing a sustainable platform for natural resource recovery, aiming to create a carbon-neutral future. The company has introduced a novel method known as Pulsed Electrical Well Stimulation (PEWS), which is a patent-pending technology designed to replace traditional hydraulic fracturing. This innovative approach eliminates the need for water injection and addresses the logistical challenges and environmental risks associated with conventional fracking methods. By utilizing high-voltage electricity and proprietary modeling techniques, Eden enhances rock permeability with precision, facilitating effective resource extraction across various geological settings. This technology not only reduces costs but also minimizes the negative impacts typically associated with hydraulic fracturing, positioning Eden as a leader in environmentally responsible resource recovery.

Atlantic Quantum is a company focused on developing scalable quantum computers to address complex computational challenges. Founded in 2022, the company emphasizes the importance of fault-tolerant quantum hardware as essential for advancing the field of quantum computing. By creating reliable and efficient quantum systems, Atlantic Quantum aims to enable engineers and researchers to make significant strides in solving difficult problems that traditional computing methods struggle to address.

Florrent is a bio-based materials and energy storage company focused on addressing key challenges in global decarbonization and the electrification of transportation and buildings. It specializes in the development of energy-density ultracapacitors made from sustainable hemp biomass sourced from a network of BIPOC farmers. These ultracapacitors enhance the stability of electrical grids and facilitate the integration of renewable energy sources, electric vehicles, and net-zero buildings. By enabling communities to locally generate, store, and utilize renewable power, Florrent contributes to the transition towards a resilient, renewable, and equitable energy economy.

Talking Heads Wireless is a telecommunication company that helps in energy savings for cellular networks.

The University of Massachusetts Amherst is a public research and land-grant university that offers undergraduate, master's, and doctoral programs. It serves as the flagship campus of the University of Massachusetts system. The university has multiple academic departments and research facilities that support a range of disciplines.

Aloft Systems specializes in maritime transportation by developing innovative wind propulsion technology aimed at enhancing the efficiency of existing vessels. The company focuses on creating self-contained wind propulsion units that can be integrated into ships, allowing for autonomous operation. This technology significantly reduces emissions and eliminates fuel costs, making it accessible for a wide range of vessels. By enabling shipping companies to utilize direct wind propulsion, Aloft Systems enhances cargo transportation on point-to-point routes, thereby improving delivery reliability and contributing to a more sustainable maritime industry.

Arrakis Materials converts CO₂ into carbon-negative minerals, enabling carbon storage and utilization.

Most of the world lacks risk mapping and risk modeling tools essential to insure resilience. And where such tools exist, emerging risks and a changing climate are rendering them obsolete. Prisere LLC aims to fill that gap by building capacity for climate and disaster resilience with improved risk tools, including risk communications, risk mapping and software apps, training and technical advisory services.

Stepwise specializes in home electrification services, focusing on the installation of electric vehicle (EV) chargers and heat pumps. The company has developed a software-defined smart device that connects to an electric panel, acting as an intermediary between the panel and the EV charger. This device monitors energy consumption and manages the charger, ensuring efficient and reliable charging services for clients. By leveraging this technology, Stepwise aims to enhance the accessibility and effectiveness of home electrification solutions.

Lithios is a technology company specializing in advanced lithium extraction through innovative electrochemical methods. The firm focuses on capturing and releasing lithium from complex mixtures, which are traditionally challenging to process. By leveraging breakthroughs in applied electrochemistry, Lithios offers solutions that facilitate low-cost and selective extraction of lithium from previously untapped brine resources. This approach not only enhances the efficiency of lithium recovery but also aligns with sustainable practices, supporting the growing demand for lithium in various industries, particularly in the context of an electric future.

Carbix is a company focused on converting atmospheric carbon dioxide into carbonates, which serve as raw materials for various industrial products. Utilizing innovative bioreactor technology, Carbix captures CO2 from industrial flue gas and rapidly transforms it, along with mineral inputs, into usable raw materials within hours. The company employs advanced weathering techniques powered by renewable energy or energy-from-waste, enhancing the sequestration of CO2 emissions. This process not only helps mitigate climate change by reducing atmospheric carbon but also enables businesses to source industrial materials sustainably.

InGel Therapeutics is a Cambridge, Massachusetts-based company founded in 2021 that focuses on developing stem cell therapeutics and biodegradable polymers. The company specializes in engineered cell therapy aimed at addressing neuroprotective pathways to treat retinal degeneration. By utilizing stem cells and their secretome, InGel Therapeutics seeks to provide neuroprotection for blinding diseases such as retinitis pigmentosa and macular degeneration. Their innovative approach involves using biodegradable polymers to isolate proteins of neuroprotective significance, first in vitro and subsequently in vivo, thereby enabling healthcare professionals to effectively treat patients suffering from retinal degeneration.

JETCOOL Technologies specializes in the development of microjet cooling modules aimed at enhancing the performance and longevity of high-power electronics. Founded in 2019 and based in Littleton, Massachusetts, the company leverages technology originally developed at MIT Lincoln Laboratory. By using small jets of fluid integrated into modular cooling components, JETCOOL’s solutions effectively reduce heat and power consumption in electronic devices. This innovation is particularly beneficial for industries such as aerospace, defense, and electronics, where managing heat is crucial for device reliability and efficiency.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

AeroShield specializes in the production of a super-insulating, nanoporous glass material designed for energy-efficient windows. This innovative material, made from silica aerogel, provides optical clarity akin to traditional glass while delivering insulation performance that is 50% superior to standard windows. By integrating AeroShield's technology between two glass panes, manufacturers can significantly enhance the thermal efficiency of their products. Additionally, the payback period for AeroShield-enhanced windows is up to five times faster than that of comparable high-performance windows, making it an attractive option for both manufacturers and consumers. This focus on sustainability and energy efficiency supports industry compliance goals and improves overall product performance.

Harmony is a biotechnology startup that creates human breast milk protein-based infant nutrition designed to help human babies thrive. It is the world’s first dairy-free, allergen-free and environmentally friendly infant nutrition. Harmony Baby Nutrition was established in 2018 and is based in Boston, MA.

Leuko Labs focuses on developing a non-invasive device for monitoring white blood cell counts, which is crucial for various medical situations, including chemotherapy management and the detection of severe infections. Their device, PointCheck, allows for frequent testing without the need for blood draws or laboratory infrastructure, making it more accessible for patients. This innovation aims to enhance the quality of life for immunosuppressed individuals and improve clinical outcomes by enabling healthcare providers to offer personalized treatment plans based on real-time data. By simplifying the process of white blood cell assessment, Leuko Labs contributes to more effective patient management and better survival rates.

Cyvl.ai is a technology company focused on enhancing the management of physical infrastructure assets for civil engineers and government entities. Utilizing advanced 3D mapping technology and proprietary machine learning algorithms, Cyvl.ai provides a web-based software platform that enables users to efficiently gather and analyze data on various infrastructure elements such as roads, sidewalks, signs, and trees. Their vehicle-mounted mapping sensors streamline the process of infrastructure inspections, ultimately saving time and improving safety. The platform's capability for direct integration with other asset management tools further facilitates effective data utilization, making it a valuable resource for managing infrastructure assets more effectively and affordably.

Kinto.Care is an online platform designed to enhance communication and support for caregivers, particularly those caring for loved ones with dementia. The platform offers user-generated content and digital tools that facilitate care team collaboration, medication management, and tracking of health data. By providing practical advice, care planning, and group learning opportunities, Kinto.Care aims to empower family members to effectively coordinate care and manage their loved ones' medical needs through a unified interface.

ActivSignal is a biotech company that develops protein profiling for diagnostics and other applications. The company was founded in 2016 and is headquartered in Natick, Massachusetts.

Pison is a human performance company focused on enhancing cognitive and physiological capabilities through gesture control technology. The company develops a wearable technology that utilizes patented electroneurography to create a gesture-controlled ecosystem. Its advanced biopotential sensor allows for highly sensitive interaction in various applications, including virtual reality, full-body prosthetics, and exoskeletons. By integrating hardware, software, and machine learning, Pison aims to transform human-computer interaction, thereby improving users' quality of life. The company collaborates with notable partners and investors, including Special Forces, the Air Force, and NASA.

Reveal Pharmaceuticals focuses on developing innovative MRI contrast agents that provide a gadolinium-free alternative to existing gadolinium-based contrast agents (GBCAs). The company aims to enhance medical imaging safety for all patients, particularly those at risk from gadolinium exposure. Its pipeline includes precision imaging agents designed to assist in the diagnosis and treatment of conditions such as pulmonary embolism and cancer. By integrating its patented gadolinium-free RVP platform with targeted molecular probes, Reveal Pharmaceuticals enables healthcare professionals to conduct safer scans without the need for biopsies, thereby supporting the advancement of targeted therapeutics and personalized medicine.

EnVision Endoscopy specializes in developing medical devices for endoscopic surgeries, focusing on enhancing clinical outcomes for patients and efficiency for healthcare providers. The company's flagship product is an image-guided suturing system that attaches to standard flexible endoscopes, facilitating tissue approximation during surgical procedures. This biodegradable, single-use device simplifies various surgical tasks, making it more accessible for gastroenterologists and surgeons. By streamlining procedures, EnVision Endoscopy aims to reduce both procedure times and associated mortality rates, thereby improving overall patient care in the medical field.

Eden is focused on developing a sustainable platform for natural resource recovery, aiming to create a carbon-neutral future. The company has introduced a novel method known as Pulsed Electrical Well Stimulation (PEWS), which is a patent-pending technology designed to replace traditional hydraulic fracturing. This innovative approach eliminates the need for water injection and addresses the logistical challenges and environmental risks associated with conventional fracking methods. By utilizing high-voltage electricity and proprietary modeling techniques, Eden enhances rock permeability with precision, facilitating effective resource extraction across various geological settings. This technology not only reduces costs but also minimizes the negative impacts typically associated with hydraulic fracturing, positioning Eden as a leader in environmentally responsible resource recovery.

Radical Plastics, Inc., based in Winchester, Massachusetts, develops biodegradable plastic compounds designed to address plastic pollution. Incorporated in 2018, the company utilizes a proprietary, naturally occurring catalyst to blend with conventional plastics, making them fully biodegradable in the natural environment. Their innovative technology offers soil degradable compounds specifically for agricultural film, providing an economically viable solution for brands seeking drop-in replacements for traditional plastics. Through its commitment to sustainability, Radical Plastics aims to contribute to reducing plastic waste and promoting environmental health.

Gradient is a developer of secure software that addresses fundamental issues of trust and authenticity in the digital landscape. The company's solutions focus on redefining identity and data authentication, providing a framework for establishing trust and facilitating the sharing of provable statements while ensuring privacy and security. This enables users to collaborate openly without sacrificing digital security or integrity. Gradient's infrastructure is designed to foster decentralized trust, contributing to safer and more reliable digital interactions.

Jaxon.AI is an artificial intelligence platform designed to assist data science teams throughout the research, design, and build process. By leveraging technologies such as ChatGPT, Jaxon addresses complex, use case-specific challenges and creates detailed blueprints that guide users in adhering to optimal development paths. Its proprietary reasoning engine simulates model performance to evaluate trade-offs, allowing teams to identify the most effective solutions for their projects. This structured approach enhances the likelihood of success in AI initiatives, streamlining the design cycle and ensuring that users can navigate the complexities of AI development effectively.

Leuko Labs focuses on developing a non-invasive device for monitoring white blood cell counts, which is crucial for various medical situations, including chemotherapy management and the detection of severe infections. Their device, PointCheck, allows for frequent testing without the need for blood draws or laboratory infrastructure, making it more accessible for patients. This innovation aims to enhance the quality of life for immunosuppressed individuals and improve clinical outcomes by enabling healthcare providers to offer personalized treatment plans based on real-time data. By simplifying the process of white blood cell assessment, Leuko Labs contributes to more effective patient management and better survival rates.

Extend Biosciences Inc. is an emerging biotechnology company developing a novel drug delivery platform technology that improves the pharmacokinetic properties of peptides and proteins. Peptides have been particularly challenging to bring to market because they are removed from circulation prior to administering therapeutic value. Their proprietary platform technology significantly improves the circulating half-life and bioavailability of peptides and proteins, enabling the scientific community to truly develop potent and specific drugs. Their mission is to revolutionize drug delivery and give patients a better quality of life.

AmberGen, Inc. is a privately-held company based in the Boston area, established in 1995 to commercialize innovative photonic technology originally developed at Boston University. The company focuses on advancing therapeutics and diagnostics by addressing significant challenges in medicine. AmberGen employs patented techniques in proteomics and utilizes light-based control of biomolecules to create photocleavable linkers and protein engineering reagents. Its services encompass drug discovery, the development of high-throughput multiplex immuno-diagnostic assays, and mass spectrometric imaging for advanced tissue and array scanning. These innovations enable medical practitioners to detect diseases at earlier stages, thereby enhancing diagnostic capabilities and improving patient outcomes.

Mesodyne is an engineering and manufacturing company focused on innovative electricity generation solutions, particularly through its patented LightCell technology, which converts various fuels into electricity using light. Founded in 2018 by Drs. Veronika Stelmakh and Walker Chan, the company aims to deliver portable and reliable power generation systems to military and commercial users. Mesodyne's compact power generators enhance the endurance of small autonomous systems, offering efficient and long-lasting energy sources that bridge the gap between traditional batteries and internal combustion engines. This technology is designed to alleviate the burden on dismounted warfighters and emergency responders while extending the operational range of unmanned vehicles, wearables, and other equipment.

Aclarity, LLC is a cleantech startup established in 2017 and based in the United States. The company specializes in manufacturing and marketing advanced water purification devices designed for residential use. Aclarity's systems utilize innovative electrochemical technology to effectively eliminate a wide range of contaminants, including pathogens, metals, volatile organic compounds (VOCs), per- and polyfluoroalkyl substances (PFAS), and ammonia from water. These devices provide customers with cost-effective and low-maintenance solutions for comprehensive water treatment, addressing the pressing need for clean water in homes and contributing to broader environmental sustainability efforts.

The principal mission of the Company is to provide technology and technology services to industry and public sector agencies for enhanced productivity, improved safety, and reduced costs.

PathMaker Neurosystems is a neurotechnology company focused on developing non-invasive treatments for serious neurological disorders, particularly neuromotor conditions. The company is advancing a platform that employs neuronal hyperexcitability suppression, utilizing a multi-site, precision-targeted neuromodulatory approach. Initially, PathMaker is applying this innovative technology to address issues related to stroke and amyotrophic lateral sclerosis (ALS). They are in the process of manufacturing a non-invasive device specifically designed to treat post-stroke spasticity. This novel approach enables the regulation of motor neuron excitability, allowing patients to receive effective treatment without the need for drugs or surgery.